A global action agenda for turning the tide on fatty liver disease - Inserm - Institut national de la santé et de la recherche médicale Accéder directement au contenu
Article Dans Une Revue Hepatology Année : 2023

A global action agenda for turning the tide on fatty liver disease

1 University of Barcelona
2 The Graduate Center - CUNY Graduate Center
3 ILF - EASL International Liver Foundation [Geneva, Switzerland]
4 IC - Independent consultant [Nottingham, UK]
5 Mayo Clinic [Rochester]
6 LONDON ONTARIO - Med - Department of Medicine
7 Schulich School of Medicine and Dentistry
8 UC - Pontificia Universidad Católica de Chile
9 SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD - Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale
10 ISSPAM - Institut des sciences de la santé publique [Marseille]
11 The Houston Methodist Research Institute
12 QMUL - Queen Mary University of London
13 ALH - Arizona Liver Health [Phoenix, Arizona, USA]
14 KFSH & RC - King Faisal Specialist Hospital and Research Centre
15 Newcastle University [Newcastle]
16 IDIBAPS - Institut d'Investigacions Biomèdiques August Pi i Sunyer
17 Leipzig University / Universität Leipzig
18 University of Dundee
19 Unipd - Università degli Studi di Padova = University of Padua
20 Hospital Medica Sur [Mexico City, Mexico]
21 Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán - National Institute of Medical Science and Nutrition Salvador Zubiran [Mexico]
22 Universidade de Lisboa
23 UF - University of Florida [Gainesville]
24 GPA - Greek Patients Association [Athens, Greece]
25 PIMER - Postgraduate Institute of Medical Education and Research [Chandigarh, India]
26 UZA - Antwerp University Hospital [Edegem]
27 UA - University of Antwerp
28 National Council of Research [Pisa, Italy]
29 Karolinska Institutet [Stockholm]
30 Kautz 5 gUG [Köln, Germany]
31 IR - Independent researcher [Ponte de Lima, Portugal]
32 OUH - Odense University Hospital
33 Birmingham Women's and Children's NHS Foundation Trust
34 University of Birmingham [Birmingham]
35 University of Chicago
36 ILBS - Institute of Liver and Biliary Sciences [New Delhi, India]
37 Hospital Universitario Austral
38 University of Cape Town
39 USC - University of Southern California
40 Royal Free Hospital [London, UK]
41 Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico
42 UNIMIB - Università degli Studi di Milano-Bicocca = University of Milano-Bicocca
43 University of Haifa [Haifa]
44 Tel Aviv Sourasky Medical Center [Te Aviv]
45 University Medical Center [Mainz]
46 CUHK - The Chinese University of Hong Kong [Hong Kong]
47 IHVI - Inova Heart and Vascular Institute [Falls Church, VA, USA]
Jeffrey V Lazarus
Alina M Allen
William Alazawi
Quentin M Anstee
Thomas Berg
Paul N Brennan
Helena Cortez-Pinto
Kenneth Cusi
Hannes Hagström
Terry T K Huang
Dana Ivancovsky Wajcman
Aleksander Aleksander Krag
Diana Romero
C Wendy Spearman
Norah A Terrault
Emmanuel A Tsochatzis
Marcela Villota-Rivas
Jörn M Schattenberg

Résumé

Background and aims: Fatty liver disease is a major public health threat due to its very high prevalence and related morbidity and mortality. Focused and dedicated interventions are urgently needed to target disease prevention, treatment, and care. Approach and results: We developed an aligned, prioritized action agenda for the global fatty liver disease community of practice. Following a Delphi methodology over 2 rounds, a large panel (R1 n = 344, R2 n = 288) reviewed the action priorities using Qualtrics XM, indicating agreement using a 4-point Likert-scale and providing written feedback. Priorities were revised between rounds, and in R2, panelists also ranked the priorities within 6 domains: epidemiology, treatment and care, models of care, education and awareness, patient and community perspectives, and leadership and public health policy. The consensus fatty liver disease action agenda encompasses 29 priorities. In R2, the mean percentage of "agree" responses was 82.4%, with all individual priorities having at least a super-majority of agreement (> 66.7% "agree"). The highest-ranked action priorities included collaboration between liver specialists and primary care doctors on early diagnosis, action to address the needs of people living with multiple morbidities, and the incorporation of fatty liver disease into relevant non-communicable disease strategies and guidance. Conclusions: This consensus-driven multidisciplinary fatty liver disease action agenda developed by care providers, clinical researchers, and public health and policy experts provides a path to reduce the prevalence of fatty liver disease and improve health outcomes. To implement this agenda, concerted efforts will be needed at the global, regional, and national levels.

Mots clés

Fichier principal
Vignette du fichier
AASLD2023_Lazarus.pdf (2.2 Mo) Télécharger le fichier
Origine : Publication financée par une institution
Licence : CC BY - Paternité

Dates et versions

inserm-04544391 , version 1 (12-04-2024)

Identifiants

Citer

Jeffrey V Lazarus, Henry E Mark, Alina M Allen, Juan Pablo Arab, Patrizia Carrieri, et al.. A global action agenda for turning the tide on fatty liver disease. Hepatology, 2023, 79, pp.502 - 523. ⟨10.1097/hep.0000000000000545⟩. ⟨inserm-04544391⟩
5 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More