A global action agenda for turning the tide on fatty liver disease - Inserm - Institut national de la santé et de la recherche médicale
Article Dans Une Revue Hepatology Année : 2023

A global action agenda for turning the tide on fatty liver disease

Jeffrey V Lazarus (1, 2) , Henry E Mark (3, 4) , Alina M Allen (5) , Juan Pablo Arab (6, 7, 8) , Patrizia Carrieri (9, 10) , Mazen Noureddin (11) , William Alazawi (12) , Naim Alkhouri (13) , Saleh A Alqahtani (14) , Quentin M Anstee (15) , Marco Arrese (8) , Ramon Bataller (16) , Thomas Berg (17) , Paul N Brennan (18) , Patrizia Burra (19) , Graciela E Castro-Narro (20, 21) , Helena Cortez-Pinto (22) , Kenneth Cusi (23) , Nikos Dedes (24) , Ajay Duseja (25) , Sven M Francque (26, 27) , Amalia Gastaldelli (28) , Hannes Hagström (29) , Terry T K Huang (2) , Dana Ivancovsky Wajcman (1) , Achim Kautz (30) , Christopher J Kopka (31) , Aleksander Aleksander Krag (32) , Philip N Newsome (33, 34) , Mary E Rinella (35) , Diana Romero (2) , Shiv Kumar Sarin (36) , Marcelo Silva (37) , C Wendy Spearman (38) , Norah A Terrault (39) , Emmanuel A Tsochatzis (40) , Luca Valenti (41, 42) , Marcela Villota-Rivas (1) , Shira Zelber-Sagi (43, 44) , Jörn M Schattenberg (45) , Vincent Wai-Sun Wong (46) , Zobair M Younossi (47)
1 University of Barcelona
2 The Graduate Center - CUNY Graduate Center
3 ILF - EASL International Liver Foundation [Geneva, Switzerland]
4 IC - Independent consultant [Nottingham, UK]
5 Mayo Clinic [Rochester]
6 LONDON ONTARIO - Med - Department of Medicine
7 Schulich School of Medicine and Dentistry
8 UC - Pontificia Universidad Católica de Chile
9 SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD - Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale
10 ISSPAM - Institut des sciences de la santé publique [Marseille]
11 The Houston Methodist Research Institute
12 QMUL - Queen Mary University of London
13 ALH - Arizona Liver Health [Phoenix, Arizona, USA]
14 KFSH & RC - King Faisal Specialist Hospital and Research Centre
15 Newcastle University [Newcastle]
16 IDIBAPS - Institut d'Investigacions Biomèdiques August Pi i Sunyer
17 Leipzig University / Universität Leipzig
18 University of Dundee
19 Unipd - Università degli Studi di Padova = University of Padua
20 Hospital Medica Sur [Mexico City, Mexico]
21 Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán - National Institute of Medical Science and Nutrition Salvador Zubiran [Mexico]
22 ULISBOA - Universidade de Lisboa = University of Lisbon = Université de Lisbonne
23 UF - University of Florida [Gainesville]
24 GPA - Greek Patients Association [Athens, Greece]
25 PIMER - Postgraduate Institute of Medical Education and Research [Chandigarh, India]
26 UZA - Antwerp University Hospital [Edegem]
27 UA - University of Antwerp
28 National Council of Research [Pisa, Italy]
29 Karolinska Institutet [Stockholm]
30 Kautz 5 gUG [Köln, Germany]
31 IR - Independent researcher [Ponte de Lima, Portugal]
32 OUH - Odense University Hospital
33 Birmingham Women's and Children's NHS Foundation Trust
34 University of Birmingham [Birmingham]
35 University of Chicago
36 ILBS - Institute of Liver and Biliary Sciences [New Delhi, India]
37 Hospital Universitario Austral
38 University of Cape Town
39 USC - University of Southern California
40 Royal Free Hospital [London, UK]
41 Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico
42 UNIMIB - Università degli Studi di Milano-Bicocca = University of Milano-Bicocca
43 University of Haifa [Haifa]
44 Tel Aviv Sourasky Medical Center [Tel Aviv]
45 University Medical Center [Mainz]
46 CUHK - The Chinese University of Hong Kong [Hong Kong]
47 IHVI - Inova Heart and Vascular Institute [Falls Church, VA, USA]
Jeffrey V Lazarus
University of Barcelona
CUNY Graduate Center
Henry E Mark
EASL International Liver Foundation [Geneva, Switzerland]
Independent consultant [Nottingham, UK]
Alina M Allen
Mayo Clinic [Rochester]
Juan Pablo Arab
Department of Medicine
Schulich School of Medicine and Dentistry
Pontificia Universidad Católica de Chile
Patrizia Carrieri
Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale
Institut des sciences de la santé publique [Marseille]
Mazen Noureddin
The Houston Methodist Research Institute
William Alazawi
Queen Mary University of London
Naim Alkhouri
Arizona Liver Health [Phoenix, Arizona, USA]
Saleh A Alqahtani
King Faisal Specialist Hospital and Research Centre
Quentin M Anstee
Newcastle University [Newcastle]
Marco Arrese
  • Fonction : Auteur
Pontificia Universidad Católica de Chile
Ramon Bataller
Institut d'Investigacions Biomèdiques August Pi i Sunyer
Thomas Berg
Leipzig University / Universität Leipzig
Paul N Brennan
University of Dundee
Patrizia Burra
Università degli Studi di Padova = University of Padua
Graciela E Castro-Narro
Hospital Medica Sur [Mexico City, Mexico]
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán - National Institute of Medical Science and Nutrition Salvador Zubiran [Mexico]
Helena Cortez-Pinto
Universidade de Lisboa = University of Lisbon = Université de Lisbonne
Kenneth Cusi
University of Florida [Gainesville]
Nikos Dedes
  • Fonction : Auteur
Greek Patients Association [Athens, Greece]
Ajay Duseja
Postgraduate Institute of Medical Education and Research [Chandigarh, India]
Sven M Francque
Antwerp University Hospital [Edegem]
University of Antwerp
Amalia Gastaldelli
National Council of Research [Pisa, Italy]
Hannes Hagström
Karolinska Institutet [Stockholm]
Terry T K Huang
CUNY Graduate Center
Dana Ivancovsky Wajcman
University of Barcelona
Achim Kautz
  • Fonction : Auteur
Kautz 5 gUG [Köln, Germany]
Christopher J Kopka
Independent researcher [Ponte de Lima, Portugal]
Aleksander Aleksander Krag
Odense University Hospital
Philip N Newsome
Birmingham Women's and Children's NHS Foundation Trust
University of Birmingham [Birmingham]
Mary E Rinella
  • Fonction : Auteur
University of Chicago
Diana Romero
CUNY Graduate Center
Shiv Kumar Sarin
Institute of Liver and Biliary Sciences [New Delhi, India]
Marcelo Silva
  • Fonction : Auteur
Hospital Universitario Austral
C Wendy Spearman
University of Cape Town
Norah A Terrault
University of Southern California
Emmanuel A Tsochatzis
Royal Free Hospital [London, UK]
Luca Valenti
Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico
Università degli Studi di Milano-Bicocca = University of Milano-Bicocca
Marcela Villota-Rivas
University of Barcelona
Shira Zelber-Sagi
  • Fonction : Auteur
University of Haifa [Haifa]
Tel Aviv Sourasky Medical Center [Tel Aviv]
Jörn M Schattenberg
University Medical Center [Mainz]
Vincent Wai-Sun Wong
The Chinese University of Hong Kong [Hong Kong]
Zobair M Younossi
Inova Heart and Vascular Institute [Falls Church, VA, USA]

Résumé

Background and aims: Fatty liver disease is a major public health threat due to its very high prevalence and related morbidity and mortality. Focused and dedicated interventions are urgently needed to target disease prevention, treatment, and care. Approach and results: We developed an aligned, prioritized action agenda for the global fatty liver disease community of practice. Following a Delphi methodology over 2 rounds, a large panel (R1 n = 344, R2 n = 288) reviewed the action priorities using Qualtrics XM, indicating agreement using a 4-point Likert-scale and providing written feedback. Priorities were revised between rounds, and in R2, panelists also ranked the priorities within 6 domains: epidemiology, treatment and care, models of care, education and awareness, patient and community perspectives, and leadership and public health policy. The consensus fatty liver disease action agenda encompasses 29 priorities. In R2, the mean percentage of "agree" responses was 82.4%, with all individual priorities having at least a super-majority of agreement (> 66.7% "agree"). The highest-ranked action priorities included collaboration between liver specialists and primary care doctors on early diagnosis, action to address the needs of people living with multiple morbidities, and the incorporation of fatty liver disease into relevant non-communicable disease strategies and guidance. Conclusions: This consensus-driven multidisciplinary fatty liver disease action agenda developed by care providers, clinical researchers, and public health and policy experts provides a path to reduce the prevalence of fatty liver disease and improve health outcomes. To implement this agenda, concerted efforts will be needed at the global, regional, and national levels.

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AASLD American Association

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Santé publique et épidémiologie
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Soumis le : vendredi 12 avril 2024-17:51:59

Dernière modification le : mercredi 2 octobre 2024-11:40:04

Archivage à long terme le : lundi 15 juillet 2024-11:57:56

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inserm-04544391 , version 1 (12-04-2024)

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Jeffrey V Lazarus, Henry E Mark, Alina M Allen, Juan Pablo Arab, Patrizia Carrieri, et al.. A global action agenda for turning the tide on fatty liver disease. Hepatology, 2023, 79, pp.502 - 523. ⟨10.1097/hep.0000000000000545⟩. ⟨inserm-04544391⟩

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