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Article Dans Une Revue International Journal of Bipolar Disorders Année : 2023

Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder

Michael Bauer (1, 2) , Tasha Glenn (3) , Eric D Achtyes (4) , Martin Alda (5) , Esen Agaoglu (6) , Kürsat Altınbaş (7) , Ole A Andreassen (8, 9, 10, 11) , Elias Angelopoulos (12, 13) , Raffaella Ardau (14) , Memduha Aydin (7) , Yavuz Ayhan (6) , Christopher Baethge (15) , Rita Bauer (1, 2) , Bernhard T Baune (16, 17, 18) , Ceylan Balaban (19, 20) , Claudia Becerra-Palars (21) , Aniruddh P Behere (4) , Prakash B Behere (22, 23) , Habte Belete (24) , Tilahun Belete (24) , Gabriel Okawa Belizario (25) , Frank Bellivier (26, 27, 28) , Robert H Belmaker (29) , Francesco Benedetti (30, 31) , Michael Berk (32, 33, 34, 18) , Yuly Bersudsky (29) , Şule Bicakci (35, 6) , Harriet Birabwa-Oketcho (36) , Thomas D Bjella (10, 11, 9, 8) , Conan Brady (37, 38) , Jorge Cabrera (39) , Marco Cappucciati (40) , Angela Marianne Paredes Castro (32, 34) , Wei-Ling Chen (41) , Eric y W Cheung (42) , Silvia Chiesa (40) , Marie Crowe (43) , Alessandro Cuomo (44) , Sara Dallaspezia (31) , Maria del Zompo (14) , Pratikkumar Desai (4) , Seetal Dodd (32, 33, 34) , Bruno Etain (26, 27, 45) , Andrea Fagiolini (44) , Frederike T Fellendorf (46) , Ewa Ferensztajn-Rochowiak (47) , Jess G Fiedorowicz (48, 49) , Kostas N Fountoulakis (50) , Mark A Frye (51) , Pierre A Geoffroy (52, 53, 54, 55, 56) , Michael J Gitlin (57, 58) , Ana Gonzalez-Pinto (59, 60, 61, 62) , John F Gottlieb (63) , Paul Grof (64) , Bartholomeus C M Haarman (65, 66) , Hirohiko Harima (67) , Mathias Hasse-Sousa (68) , Chantal Henry (53) , Lone Hoffding (69) , Josselin Houenou (70, 71, 72, 27) , Massimiliano Imbesi (40) , Erkki T Isometsä (73, 74, 75) , Maja Ivkovic (76) , Sven Janno (77) , Simon Johnsen (78) , Flávio Kapczinski (68) , Gregory N Karakatsoulis (50) , Mathias Kardell (79, 80) , Lars Vedel Kessing (81) , Seong Jae Kim (82) , Barbara König (83) , Timur L Kot (84) , Michael Koval (85) , Mauricio Kunz (68) , Beny Lafer (25) , Mikael Landén (79, 86, 80, 87) , Erik R Larsen (69) , Melanie Lenger (46) , Rasmus W Licht (88, 78) , Carlos Lopez-Jaramillo (89, 90) , Alan Mackenzie (91, 92) , Helle Østergaard Madsen (93) , Simone Alberte Kongstad A Madsen (78) , Jayant Mahadevan (94) , Agustine Mahardika (95) , Mirko Manchia (5, 14) , Wendy Marsh (96) , Monica Martinez-Cengotitabengoa (97, 60, 59, 98) , Julia Martini (1, 2) , Klaus Martiny (93) , Yuki Mashima (99) , Declan M Mcloughlin (37, 38) , Ybe Meesters (65, 66) , Ingrid Melle (8, 10, 9, 11) , Fátima Meza-Urzúa (100) , Pavol Mikolas (1, 2) , Yee Ming Mok (101) , Scott Monteith (4) , Muthukumaran Moorthy (102) , Gunnar Morken (103, 104) , Enrica Mosca (14) , Anton A Mozzhegorov (105) , Rodrigo Munoz (106) , Starlin V Mythri (107) , Fethi Nacef (108) , Ravi K Nadella (102) , Takako Nakanotani (109) , René Ernst Nielsen (88, 78) , Claire O’donovan (5) , Adel Omrani (110) , Yamima Osher (29) , Uta Ouali (108, 111) , Maja Pantovic-Stefanovic (76) , Pornjira Pariwatcharakul (112, 113) , Joanne Petite (5) , Johannes Petzold (1, 2) , Andrea Pfennig (1, 2) , Yolanda Pica Ruiz (114) , Marco Pinna (14, 115) , Maurizio Pompili (116, 117) , Richard J Porter (118) , Danilo Quiroz (119) , Francisco Diego Rabelo-Da-Ponte (120) , Raj Ramesar (121) , Natalie Rasgon (122) , Woraphat Ratta-Apha (112) , Michaela Ratzenhofer (46) , Maria Redahan (37, 38) , M S Reddy (123, 124) , Andreas Reif (19, 125) , Eva Z Reininghaus (46) , Jenny Gringer Richards (126) , Philipp Ritter (1, 2) , Janusz K Rybakowski (47) , Leela Sathyaputri (126) , Angela M Scippa (127) , Christian Simhandl (83, 128) , Daniel Smith (129) , José Smith (130) , Paul W Stackhouse (131) , Dan J Stein (121) , Kellen Stilwell (4) , Sergio Strejilevich (130) , Kuan-Pin Su (132, 133) , Mythily Subramaniam (101) , Ahmad Hatim Sulaiman (134) , Kirsi Suominen (135) , Andi J Tanra (136) , Yoshitaka Tatebayashi (109) , Wen Lin Teh (101) , Leonardo Tondo (137, 138) , Carla Torrent (139, 140, 141) , Daniel Tuinstra (4) , Takahito Uchida (99, 33) , Arne E Vaaler (103, 104) , Eduard Vieta (139, 140, 141) , Biju Viswanath (102) , Maria Yoldi-Negrete (21) , Oguz Kaan Yalcinkaya (6) , Allan H Young (142) , Yosra Zgueb (108, 111) , Peter C Whybrow (58)
1 University Hospital Carl Gustav Carus [Dresden, Germany]
2 TU Dresden - Technische Universität Dresden = Dresden University of Technology
3 CRA - ChronoRecord Association [Fullerton, CA, USA]
4 MSUCUM - Michigan State University College of Human Medicine [Grand Rapids, MI, USA]
5 Dalhousie University [Halifax]
6 Faculty of Medicine [Hacettepe University]
7 Selçuk University = Selçuk Üniversitesi
8 NORMENT - Norwegian Centre for Mental Disorders Research [Oslo]
9 Institute of Clinical Medicine [Oslo]
10 Oslo University Hospital [Oslo]
11 UiO - University of Oslo
12 UOA - Université d'Athènes
13 Eginition Hospital
14 UniCa - Università degli Studi di Cagliari = University of Cagliari
15 University Hospital of Cologne [Cologne]
16 WWU - Westfälische Wilhelms-Universität Münster = University of Münster
17 Melbourne Medical School [Melbourne]
18 The Florey Institute of Neuroscience and Mental Health
19 Frankfurt University Hospital
20 Goethe-Universität Frankfurt am Main
21 INPRF - National Institute of Psychiatry Ramón de la Fuente Muñiz [Mexico City]
22 Deemed University - Datta Meghe Institute of Medical Sciences [Wardha, India]
23 Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
24 BDU - Bahir Dar University
25 USP - Universidade de São Paulo = University of São Paulo
26 OPTeN (UMR_S 1144 / U1144) - Optimisation thérapeutique en Neuropsychopharmacologie
27 Fondation FondaMental [Créteil]
28 Pôle de Psychiatrie [Hôpital Henri Mondor]
29 BGU - Ben-Gurion University of the Negev
30 UniSR - Universita Vita Salute San Raffaele = Vita-Salute San Raffaele University [Milan, Italie]
31 San Raffaele Scientific Institute
32 Deakin University [Burwood]
33 University of Melbourne
34 Barwon Health - IMPACT Strategic Research Centre [VIC, Australia]
35 Başkent University Hospital [Adana, Turkey]
36 Butabika Hospital [Kampala, Uganda]
37 Trinity College Dublin
38 StPUH - St. Patrick's University Hospital [Dublin, Ireland]
39 Mood Disorders Clinic, Dr. Jose Horwitz Psychiatric Institute,
40 DMHSA - Department of Mental Health and Substance Abuse [Piacenza, Italy]
41 TVGH - Taichung Veterans General Hospital [Chiayi, Taiwan]
42 P2C - Private Practice, Central [Hong Kong, China ]
43 University of Otago [Dunedin, Nouvelle-Zélande]
44 UNISI - Università degli Studi di Siena = University of Siena
45 Hôpital Albert Chenevier
46 Medical University Graz
47 PUMS - Poznan University of Medical Sciences [Poland]
48 University of Ottawa [Ottawa]
49 The Ottawa Hospital
50 Aristotle University of Thessaloniki
51 Mayo Clinic [Rochester]
52 GHU AP-HP Nord - Université Paris Cité
53 GHU Paris Psychiatrie et Neurosciences
54 NeuroDiderot (UMR_S_1141 / U1141) - Maladies neurodéveloppementales et neurovasculaires
55 CIC Hôpital Bichat
56 FHU I2-D2 - FHU I2 - D2 [Paris]
57 Semel Institute for Neuroscience and Human Behavior [Los Angeles, Ca]
58 UCLA - University of California [Los Angeles]
59 UPV / EHU - University of the Basque Country = Euskal Herriko Unibertsitatea
60 Bioaraba Health Research Institute
61 Hospital Universitario de Araba = Araba University Hospital
62 CIBER-SAM - Centro de Investigación Biomédica en Red Salud Mental [Madrid]
63 Feinberg School of Medicine
64 University of Toronto
65 UMCG - University Medical Center Groningen [Groningen]
66 University of Groningen [Groningen]
67 Tokyo Metropolitan Matsuzawa Hospital [Tokyo, Japan]
68 UFRGS - Universidade Federal do Rio Grande do Sul [Porto Alegre]
69 SDU - University of Southern Denmark
70 IMRB - Institut Mondor de Recherche Biomédicale
71 NEUROSPIN - Service NEUROSPIN
72 CHU Henri Mondor [Créteil]
73 Helsingin yliopisto = Helsingfors universitet = University of Helsinki
74 HUS - Helsinki University Hospital [Finland]
75 National Institute for Health and Welfare [Helsinki]
76 University Clinical Centre of Serbia
77 University of Tartu
78 AUH - Aalborg University Hospital [Aalborg, Denmark]
79 GU - Göteborgs Universitet = University of Gothenburg
80 Institute of Neuroscience and Physiology [Göteborg]
81 CADIC - Copenhagen Affective Disorder Research Center [Copenhagen, Denmark]
82 CUSM - Chosun University School of Medicine [Gwangju, Republic of Korea]
83 BIPOLAR Zentrum Wiener Neustadt [Wiener Neustadt, Austria]
84 Khanty-Mansiysk Clinical Psychoneurological Hospital [Khanty-Mansiysk, Russia]
85 Michigan State University [East Lansing]
86 Karolinska Institutet [Stockholm]
87 Sahlgrenska Academy at University of Gothenburg [Göteborg]
88 AAU - Aalborg University [Denmark]
89 Universidad de Antioquia = University of Antioquia [Medellín, Colombia]
90 HSVFM - Hospital San Vicente Fundación - Medellín [Antioquia, Colombia]
91 University of Glasgow
92 NHSGGC - NHS Greater Glasgow & Clyde [Glasgow]
93 Copenhagen University Hospital
94 National Institute of Mental Health and Neurosciences [Bagalore, India]
95 UM - Universitas Mataram [Mataram, Indonesia]
96 UMASS - University of Massachusetts Medical School [Worcester]
97 Osakidetza-Basque Health Service
98 PCEA - The Psychology Clinic of East Anglia [Norwich, UK]
99 Keio University School of Medicine [Tokyo, Japan]
100 SHGK - SHG Klinikum [Idar-Oberstein, Germany]
101 Institute of Mental Health [Singapore]
102 NIMHANS - National Institute of Mental Health and Neurosciences [Bangalore, Inde]
103 NTNU - Norwegian University of Science and Technology
104 St. Olav's University Hospital - St. Olavs Hospital HF
105 Soviet Psychoneurological Hospital [Urai, Russia]
106 UC San Diego - University of California [San Diego]
107 MCLGH - Makunda Christian Leprosy and General Hospital [Assam, India]
108 University of Tunis El Manar
109 TMHH - Tokyo Metropolitan Hiroo Hospital [Tokyo, Japan]
110 TBF - Tunisian Bipolar Forum [Tunis, Tunisia]
111 Hopital de Razi - Razi Hospital [Tunis]
112 Mahidol University [Bangkok]
113 Siriraj Hospital, Mahidol University
114 Hospital Ángeles del Pedregal [Mexico City, Mexico]
115 Centro Lucio Bini [Cagliari, Italy]
116 Azienda Ospedaliera Sant'Andrea [Roma]
117 UNIROMA - Università degli Studi di Roma "La Sapienza" = Sapienza University [Rome]
118 UO - University of Otago [Christchurch, New Zealand]
119 UDP - Universidad Diego Portales [Santiago - Chili]
120 UCLAN - University of Central Lancashire [Preston]
121 University of Cape Town
122 Stanford School of Medicine [Stanford]
123 ABC - Asha Bipolar Clinic [Hyderabad, Telangana, India]
124 AH - Asha Hospital [Telangana, India]
125 Goethe University Frankfurt
126 University of Iowa [Iowa City]
127 UEFS - Universidade Estadual de Feira de Santana [Bahia]=State University of Feira de Santana
128 SFU - Sigmund Freud University
129 Edin. - University of Edinburgh
130 AREA - Assistance and Research in Affective Disorders [Buenos Aires, Argentina]
131 LaRC - NASA Langley Research Center [Hampton]
132 China Medical University Hospital [Taichung]
133 TCMAH - Tainan City Municipal Annan Hospital [Tainan, Taiwan]
134 Faculty of Medicine, University of Malaya [Kuala Lumpur, Malaisie]
135 Department of Psychiatry [Helsinki]
136 Unhas - Hasanuddin University
137 McLean Hospital [Belmont, Ma.]
138 HMS - Harvard Medical School [Boston]
139 University of Barcelona
140 IDIBAPS - Institut d'Investigacions Biomèdiques August Pi i Sunyer
141 CIBERSAM - Centro de Investigación Biomédica en Red de Salud Mental [Barcelona, Spain]
142 Institute of Psychiatry, Psychology & Neuroscience, King's College London
Paul Grof
  • Fonction : Auteur
Sven Janno
  • Fonction : Auteur

Résumé

Background: Sunlight contains ultraviolet B (UVB) radiation that triggers the production of vitamin D by skin. Vitamin D has widespread effects on brain function in both developing and adult brains. However, many people live at latitudes (about > 40 N or S) that do not receive enough UVB in winter to produce vitamin D. This exploratory study investigated the association between the age of onset of bipolar I disorder and the threshold for UVB sufficient for vitamin D production in a large global sample. Methods: Data for 6972 patients with bipolar I disorder were obtained at 75 collection sites in 41 countries in both hemispheres. The best model to assess the relation between the threshold for UVB sufficient for vitamin D production and age of onset included 1 or more months below the threshold, family history of mood disorders, and birth cohort. All coefficients estimated at P ≤ 0.001. Results: The 6972 patients had an onset in 582 locations in 70 countries, with a mean age of onset of 25.6 years. Of the onset locations, 34.0% had at least 1 month below the threshold for UVB sufficient for vitamin D production. The age of onset at locations with 1 or more months of less than or equal to the threshold for UVB was 1.66 years younger. Conclusion: UVB and vitamin D may have an important influence on the development of bipolar disorder. Study limitations included a lack of data on patient vitamin D levels, lifestyles, or supplement use. More study of the impacts of UVB and vitamin D in bipolar disorder is needed to evaluate this supposition.
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Origine : Publication financée par une institution
Licence : CC BY - Paternité

Dates et versions

inserm-04165238 , version 1 (18-07-2023)

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Citer

Michael Bauer, Tasha Glenn, Eric D Achtyes, Martin Alda, Esen Agaoglu, et al.. Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder. International Journal of Bipolar Disorders, 2023, 11 (1), pp.22. ⟨10.1186/s40345-023-00303-w⟩. ⟨inserm-04165238⟩
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