Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder
Michael Bauer
(1, 2)
,
Tasha Glenn
(3)
,
Eric D Achtyes
(4)
,
Martin Alda
(5)
,
Esen Agaoglu
(6)
,
Kürsat Altınbaş
(7)
,
Ole A Andreassen
(8, 9, 10, 11)
,
Elias Angelopoulos
(12, 13)
,
Raffaella Ardau
(14)
,
Memduha Aydin
(7)
,
Yavuz Ayhan
(6)
,
Christopher Baethge
(15)
,
Rita Bauer
(1, 2)
,
Bernhard T Baune
(16, 17, 18)
,
Ceylan Balaban
(19, 20)
,
Claudia Becerra-Palars
(21)
,
Aniruddh P Behere
(4)
,
Prakash B Behere
(22, 23)
,
Habte Belete
(24)
,
Tilahun Belete
(24)
,
Gabriel Okawa Belizario
(25)
,
Frank Bellivier
(26, 27, 28)
,
Robert H Belmaker
(29)
,
Francesco Benedetti
(30, 31)
,
Michael Berk
(32, 33, 34, 18)
,
Yuly Bersudsky
(29)
,
Şule Bicakci
(35, 6)
,
Harriet Birabwa-Oketcho
(36)
,
Thomas D Bjella
(10, 11, 9, 8)
,
Conan Brady
(37, 38)
,
Jorge Cabrera
(39)
,
Marco Cappucciati
(40)
,
Angela Marianne Paredes Castro
(32, 34)
,
Wei-Ling Chen
(41)
,
Eric y W Cheung
(42)
,
Silvia Chiesa
(40)
,
Marie Crowe
(43)
,
Alessandro Cuomo
(44)
,
Sara Dallaspezia
(31)
,
Maria del Zompo
(14)
,
Pratikkumar Desai
(4)
,
Seetal Dodd
(32, 33, 34)
,
Bruno Etain
(26, 27, 45)
,
Andrea Fagiolini
(44)
,
Frederike T Fellendorf
(46)
,
Ewa Ferensztajn-Rochowiak
(47)
,
Jess G Fiedorowicz
(48, 49)
,
Kostas N Fountoulakis
(50)
,
Mark A Frye
(51)
,
Pierre A Geoffroy
(52, 53, 54, 55, 56)
,
Michael J Gitlin
(57, 58)
,
Ana Gonzalez-Pinto
(59, 60, 61, 62)
,
John F Gottlieb
(63)
,
Paul Grof
(64)
,
Bartholomeus C M Haarman
(65, 66)
,
Hirohiko Harima
(67)
,
Mathias Hasse-Sousa
(68)
,
Chantal Henry
(53)
,
Lone Hoffding
(69)
,
Josselin Houenou
(70, 71, 72, 27)
,
Massimiliano Imbesi
(40)
,
Erkki T Isometsä
(73, 74, 75)
,
Maja Ivkovic
(76)
,
Sven Janno
(77)
,
Simon Johnsen
(78)
,
Flávio Kapczinski
(68)
,
Gregory N Karakatsoulis
(50)
,
Mathias Kardell
(79, 80)
,
Lars Vedel Kessing
(81)
,
Seong Jae Kim
(82)
,
Barbara König
(83)
,
Timur L Kot
(84)
,
Michael Koval
(85)
,
Mauricio Kunz
(68)
,
Beny Lafer
(25)
,
Mikael Landén
(79, 86, 80, 87)
,
Erik R Larsen
(69)
,
Melanie Lenger
(46)
,
Rasmus W Licht
(88, 78)
,
Carlos Lopez-Jaramillo
(89, 90)
,
Alan Mackenzie
(91, 92)
,
Helle Østergaard Madsen
(93)
,
Simone Alberte Kongstad A Madsen
(78)
,
Jayant Mahadevan
(94)
,
Agustine Mahardika
(95)
,
Mirko Manchia
(5, 14)
,
Wendy Marsh
(96)
,
Monica Martinez-Cengotitabengoa
(97, 60, 59, 98)
,
Julia Martini
(1, 2)
,
Klaus Martiny
(93)
,
Yuki Mashima
(99)
,
Declan M Mcloughlin
(37, 38)
,
Ybe Meesters
(65, 66)
,
Ingrid Melle
(8, 10, 9, 11)
,
Fátima Meza-Urzúa
(100)
,
Pavol Mikolas
(1, 2)
,
Yee Ming Mok
(101)
,
Scott Monteith
(4)
,
Muthukumaran Moorthy
(102)
,
Gunnar Morken
(103, 104)
,
Enrica Mosca
(14)
,
Anton A Mozzhegorov
(105)
,
Rodrigo Munoz
(106)
,
Starlin V Mythri
(107)
,
Fethi Nacef
(108)
,
Ravi K Nadella
(102)
,
Takako Nakanotani
(109)
,
René Ernst Nielsen
(88, 78)
,
Claire O’donovan
(5)
,
Adel Omrani
(110)
,
Yamima Osher
(29)
,
Uta Ouali
(108, 111)
,
Maja Pantovic-Stefanovic
(76)
,
Pornjira Pariwatcharakul
(112, 113)
,
Joanne Petite
(5)
,
Johannes Petzold
(1, 2)
,
Andrea Pfennig
(1, 2)
,
Yolanda Pica Ruiz
(114)
,
Marco Pinna
(14, 115)
,
Maurizio Pompili
(116, 117)
,
Richard J Porter
(118)
,
Danilo Quiroz
(119)
,
Francisco Diego Rabelo-Da-Ponte
(120)
,
Raj Ramesar
(121)
,
Natalie Rasgon
(122)
,
Woraphat Ratta-Apha
(112)
,
Michaela Ratzenhofer
(46)
,
Maria Redahan
(37, 38)
,
M S Reddy
(123, 124)
,
Andreas Reif
(19, 125)
,
Eva Z Reininghaus
(46)
,
Jenny Gringer Richards
(126)
,
Philipp Ritter
(1, 2)
,
Janusz K Rybakowski
(47)
,
Leela Sathyaputri
(126)
,
Angela M Scippa
(127)
,
Christian Simhandl
(83, 128)
,
Daniel Smith
(129)
,
José Smith
(130)
,
Paul W Stackhouse
(131)
,
Dan J Stein
(121)
,
Kellen Stilwell
(4)
,
Sergio Strejilevich
(130)
,
Kuan-Pin Su
(132, 133)
,
Mythily Subramaniam
(101)
,
Ahmad Hatim Sulaiman
(134)
,
Kirsi Suominen
(135)
,
Andi J Tanra
(136)
,
Yoshitaka Tatebayashi
(109)
,
Wen Lin Teh
(101)
,
Leonardo Tondo
(137, 138)
,
Carla Torrent
(139, 140, 141)
,
Daniel Tuinstra
(4)
,
Takahito Uchida
(99, 33)
,
Arne E Vaaler
(103, 104)
,
Eduard Vieta
(139, 140, 141)
,
Biju Viswanath
(102)
,
Maria Yoldi-Negrete
(21)
,
Oguz Kaan Yalcinkaya
(6)
,
Allan H Young
(142)
,
Yosra Zgueb
(108, 111)
,
Peter C Whybrow
(58)
1
University Hospital Carl Gustav Carus [Dresden, Germany]
2 TU Dresden - Technische Universität Dresden = Dresden University of Technology
3 CRA - ChronoRecord Association [Fullerton, CA, USA]
4 MSUCUM - Michigan State University College of Human Medicine [Grand Rapids, MI, USA]
5 Dalhousie University [Halifax]
6 Faculty of Medicine [Hacettepe University]
7 Selçuk University = Selçuk Üniversitesi
8 NORMENT - Norwegian Centre for Mental Disorders Research [Oslo]
9 Institute of Clinical Medicine [Oslo]
10 Oslo University Hospital [Oslo]
11 UiO - University of Oslo
12 UOA - Université d'Athènes
13 Eginition Hospital
14 UniCa - Università degli Studi di Cagliari = University of Cagliari = Université de Cagliari
15 University Hospital of Cologne [Cologne]
16 WWU - Westfälische Wilhelms-Universität Münster = University of Münster
17 Melbourne Medical School [Melbourne]
18 The Florey Institute of Neuroscience and Mental Health
19 Frankfurt University Hospital
20 Goethe-Universität Frankfurt am Main
21 INPRF - National Institute of Psychiatry Ramón de la Fuente Muñiz [Mexico City]
22 Deemed University - Datta Meghe Institute of Medical Sciences [Wardha, India]
23 Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
24 BDU - Bahir Dar University
25 USP - Universidade de São Paulo = University of São Paulo
26 OPTeN (UMR_S 1144 / U1144) - Optimisation thérapeutique en Neuropsychopharmacologie
27 Fondation FondaMental [Créteil]
28 Pôle de Psychiatrie [Hôpital Henri Mondor]
29 BGU - Ben-Gurion University of the Negev
30 UniSR - Universita Vita Salute San Raffaele = Vita-Salute San Raffaele University [Milan, Italie]
31 San Raffaele Scientific Institute
32 Deakin University [Burwood]
33 University of Melbourne
34 Barwon Health - IMPACT Strategic Research Centre [VIC, Australia]
35 Başkent University Hospital [Adana, Turkey]
36 Butabika Hospital [Kampala, Uganda]
37 Trinity College Dublin
38 StPUH - St. Patrick's University Hospital [Dublin, Ireland]
39 Mood Disorders Clinic, Dr. Jose Horwitz Psychiatric Institute,
40 DMHSA - Department of Mental Health and Substance Abuse [Piacenza, Italy]
41 TVGH - Taichung Veterans General Hospital [Chiayi, Taiwan]
42 P2C - Private Practice, Central [Hong Kong, China ]
43 University of Otago [Dunedin, Nouvelle-Zélande]
44 UNISI - Università degli Studi di Siena = University of Siena
45 Hôpital Albert Chenevier
46 Medical University of Graz = Medizinische Universität Graz
47 PUMS - Poznan University of Medical Sciences [Poland]
48 University of Ottawa [Ottawa]
49 The Ottawa Hospital
50 Aristotle University of Thessaloniki
51 Mayo Clinic [Rochester]
52 GHU AP-HP Nord - Université Paris Cité
53 GHU Paris Psychiatrie et Neurosciences
54 NeuroDiderot (UMR_S_1141 / U1141) - Maladies neurodéveloppementales et neurovasculaires
55 CIC Hôpital Bichat
56 FHU I2-D2 - FHU I2 - D2 [Paris]
57 Semel Institute for Neuroscience and Human Behavior [Los Angeles, Ca]
58 UCLA - University of California [Los Angeles]
59 UPV / EHU - Universidad del País Vasco [Espainia] / Euskal Herriko Unibertsitatea [España] = University of the Basque Country [Spain] = Université du pays basque [Espagne]
60 Bioaraba Health Research Institute
61 Hospital Universitario de Araba = Araba University Hospital
62 CIBER-SAM - Centro de Investigación Biomédica en Red Salud Mental [Madrid]
63 [Northwestern University Medical School] - Feinberg School of Medicine [Northwestern University, Evanston]
64 University of Toronto
65 UMCG - University Medical Center Groningen [Groningen]
66 University of Groningen [Groningen]
67 Tokyo Metropolitan Matsuzawa Hospital [Tokyo, Japan]
68 UFRGS - Universidade Federal do Rio Grande do Sul [Porto Alegre]
69 SDU - University of Southern Denmark
70 IMRB - Institut Mondor de Recherche Biomédicale
71 NEUROSPIN - Service NEUROSPIN
72 CHU Henri Mondor [Créteil]
73 Helsingin yliopisto = Helsingfors universitet = University of Helsinki
74 HUS - Helsinki University Hospital [Finland]
75 National Institute for Health and Welfare [Helsinki]
76 University Clinical Centre of Serbia
77 University of Tartu
78 AUH - Aalborg University Hospital [Aalborg, Denmark]
79 GU - Göteborgs Universitet = University of Gothenburg
80 Institute of Neuroscience and Physiology [Göteborg]
81 CADIC - Copenhagen Affective Disorder Research Center [Copenhagen, Denmark]
82 CUSM - Chosun University School of Medicine [Gwangju, Republic of Korea]
83 BIPOLAR Zentrum Wiener Neustadt [Wiener Neustadt, Austria]
84 Khanty-Mansiysk Clinical Psychoneurological Hospital [Khanty-Mansiysk, Russia]
85 Michigan State University [East Lansing]
86 Karolinska Institutet [Stockholm]
87 Sahlgrenska Academy at University of Gothenburg [Göteborg]
88 AAU - Aalborg University [Denmark]
89 Universidad de Antioquia = University of Antioquia [Medellín, Colombia]
90 HSVFM - Hospital San Vicente Fundación - Medellín [Antioquia, Colombia]
91 University of Glasgow
92 NHSGGC - NHS Greater Glasgow & Clyde [Glasgow]
93 Copenhagen University Hospital
94 National Institute of Mental Health and Neurosciences [Bagalore, India]
95 UM - Universitas Mataram [Mataram, Indonesia]
96 UMASS - University of Massachusetts Medical School [Worcester]
97 Osakidetza-Basque Health Service
98 PCEA - The Psychology Clinic of East Anglia [Norwich, UK]
99 Keio University School of Medicine [Tokyo, Japan]
100 SHGK - SHG Klinikum [Idar-Oberstein, Germany]
101 Institute of Mental Health [Singapore]
102 NIMHANS - National Institute of Mental Health and Neurosciences [Bangalore, Inde]
103 NTNU - Norwegian University of Science and Technology
104 St. Olav's University Hospital - St. Olavs Hospital HF
105 Soviet Psychoneurological Hospital [Urai, Russia]
106 UC San Diego - University of California [San Diego]
107 MCLGH - Makunda Christian Leprosy and General Hospital [Assam, India]
108 University of Tunis El Manar
109 TMHH - Tokyo Metropolitan Hiroo Hospital [Tokyo, Japan]
110 TBF - Tunisian Bipolar Forum [Tunis, Tunisia]
111 Hopital de Razi - Razi Hospital [Tunis]
112 Mahidol University [Bangkok]
113 Siriraj Hospital, Mahidol University
114 Hospital Ángeles del Pedregal [Mexico City, Mexico]
115 Centro Lucio Bini [Cagliari, Italy]
116 Azienda Ospedaliera Sant'Andrea [Roma]
117 UNIROMA - Università degli Studi di Roma "La Sapienza" = Sapienza University [Rome]
118 UO - University of Otago [Christchurch, New Zealand]
119 UDP - Universidad Diego Portales [Santiago - Chili]
120 UCLAN - University of Central Lancashire [Preston]
121 University of Cape Town
122 Stanford School of Medicine [Stanford]
123 ABC - Asha Bipolar Clinic [Hyderabad, Telangana, India]
124 AH - Asha Hospital [Telangana, India]
125 Goethe University Frankfurt
126 University of Iowa [Iowa City]
127 UEFS - Universidade Estadual de Feira de Santana [Bahia]=State University of Feira de Santana
128 SFU - Sigmund Freud University
129 Edin. - University of Edinburgh
130 AREA - Assistance and Research in Affective Disorders [Buenos Aires, Argentina]
131 LaRC - NASA Langley Research Center [Hampton]
132 China Medical University Hospital [Taichung]
133 TCMAH - Tainan City Municipal Annan Hospital [Tainan, Taiwan]
134 Faculty of Medicine, University of Malaya [Kuala Lumpur, Malaisie]
135 Department of Psychiatry [Helsinki]
136 Unhas - Hasanuddin University
137 McLean Hospital [Belmont, Ma.]
138 HMS - Harvard Medical School [Boston]
139 UB - Universitat de Barcelona
140 IDIBAPS - Institut d'Investigacions Biomèdiques August Pi i Sunyer
141 CIBERSAM - Centro de Investigación Biomédica en Red de Salud Mental [Barcelona, Spain]
142 Institute of Psychiatry, Psychology & Neuroscience, King's College London
2 TU Dresden - Technische Universität Dresden = Dresden University of Technology
3 CRA - ChronoRecord Association [Fullerton, CA, USA]
4 MSUCUM - Michigan State University College of Human Medicine [Grand Rapids, MI, USA]
5 Dalhousie University [Halifax]
6 Faculty of Medicine [Hacettepe University]
7 Selçuk University = Selçuk Üniversitesi
8 NORMENT - Norwegian Centre for Mental Disorders Research [Oslo]
9 Institute of Clinical Medicine [Oslo]
10 Oslo University Hospital [Oslo]
11 UiO - University of Oslo
12 UOA - Université d'Athènes
13 Eginition Hospital
14 UniCa - Università degli Studi di Cagliari = University of Cagliari = Université de Cagliari
15 University Hospital of Cologne [Cologne]
16 WWU - Westfälische Wilhelms-Universität Münster = University of Münster
17 Melbourne Medical School [Melbourne]
18 The Florey Institute of Neuroscience and Mental Health
19 Frankfurt University Hospital
20 Goethe-Universität Frankfurt am Main
21 INPRF - National Institute of Psychiatry Ramón de la Fuente Muñiz [Mexico City]
22 Deemed University - Datta Meghe Institute of Medical Sciences [Wardha, India]
23 Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
24 BDU - Bahir Dar University
25 USP - Universidade de São Paulo = University of São Paulo
26 OPTeN (UMR_S 1144 / U1144) - Optimisation thérapeutique en Neuropsychopharmacologie
27 Fondation FondaMental [Créteil]
28 Pôle de Psychiatrie [Hôpital Henri Mondor]
29 BGU - Ben-Gurion University of the Negev
30 UniSR - Universita Vita Salute San Raffaele = Vita-Salute San Raffaele University [Milan, Italie]
31 San Raffaele Scientific Institute
32 Deakin University [Burwood]
33 University of Melbourne
34 Barwon Health - IMPACT Strategic Research Centre [VIC, Australia]
35 Başkent University Hospital [Adana, Turkey]
36 Butabika Hospital [Kampala, Uganda]
37 Trinity College Dublin
38 StPUH - St. Patrick's University Hospital [Dublin, Ireland]
39 Mood Disorders Clinic, Dr. Jose Horwitz Psychiatric Institute,
40 DMHSA - Department of Mental Health and Substance Abuse [Piacenza, Italy]
41 TVGH - Taichung Veterans General Hospital [Chiayi, Taiwan]
42 P2C - Private Practice, Central [Hong Kong, China ]
43 University of Otago [Dunedin, Nouvelle-Zélande]
44 UNISI - Università degli Studi di Siena = University of Siena
45 Hôpital Albert Chenevier
46 Medical University of Graz = Medizinische Universität Graz
47 PUMS - Poznan University of Medical Sciences [Poland]
48 University of Ottawa [Ottawa]
49 The Ottawa Hospital
50 Aristotle University of Thessaloniki
51 Mayo Clinic [Rochester]
52 GHU AP-HP Nord - Université Paris Cité
53 GHU Paris Psychiatrie et Neurosciences
54 NeuroDiderot (UMR_S_1141 / U1141) - Maladies neurodéveloppementales et neurovasculaires
55 CIC Hôpital Bichat
56 FHU I2-D2 - FHU I2 - D2 [Paris]
57 Semel Institute for Neuroscience and Human Behavior [Los Angeles, Ca]
58 UCLA - University of California [Los Angeles]
59 UPV / EHU - Universidad del País Vasco [Espainia] / Euskal Herriko Unibertsitatea [España] = University of the Basque Country [Spain] = Université du pays basque [Espagne]
60 Bioaraba Health Research Institute
61 Hospital Universitario de Araba = Araba University Hospital
62 CIBER-SAM - Centro de Investigación Biomédica en Red Salud Mental [Madrid]
63 [Northwestern University Medical School] - Feinberg School of Medicine [Northwestern University, Evanston]
64 University of Toronto
65 UMCG - University Medical Center Groningen [Groningen]
66 University of Groningen [Groningen]
67 Tokyo Metropolitan Matsuzawa Hospital [Tokyo, Japan]
68 UFRGS - Universidade Federal do Rio Grande do Sul [Porto Alegre]
69 SDU - University of Southern Denmark
70 IMRB - Institut Mondor de Recherche Biomédicale
71 NEUROSPIN - Service NEUROSPIN
72 CHU Henri Mondor [Créteil]
73 Helsingin yliopisto = Helsingfors universitet = University of Helsinki
74 HUS - Helsinki University Hospital [Finland]
75 National Institute for Health and Welfare [Helsinki]
76 University Clinical Centre of Serbia
77 University of Tartu
78 AUH - Aalborg University Hospital [Aalborg, Denmark]
79 GU - Göteborgs Universitet = University of Gothenburg
80 Institute of Neuroscience and Physiology [Göteborg]
81 CADIC - Copenhagen Affective Disorder Research Center [Copenhagen, Denmark]
82 CUSM - Chosun University School of Medicine [Gwangju, Republic of Korea]
83 BIPOLAR Zentrum Wiener Neustadt [Wiener Neustadt, Austria]
84 Khanty-Mansiysk Clinical Psychoneurological Hospital [Khanty-Mansiysk, Russia]
85 Michigan State University [East Lansing]
86 Karolinska Institutet [Stockholm]
87 Sahlgrenska Academy at University of Gothenburg [Göteborg]
88 AAU - Aalborg University [Denmark]
89 Universidad de Antioquia = University of Antioquia [Medellín, Colombia]
90 HSVFM - Hospital San Vicente Fundación - Medellín [Antioquia, Colombia]
91 University of Glasgow
92 NHSGGC - NHS Greater Glasgow & Clyde [Glasgow]
93 Copenhagen University Hospital
94 National Institute of Mental Health and Neurosciences [Bagalore, India]
95 UM - Universitas Mataram [Mataram, Indonesia]
96 UMASS - University of Massachusetts Medical School [Worcester]
97 Osakidetza-Basque Health Service
98 PCEA - The Psychology Clinic of East Anglia [Norwich, UK]
99 Keio University School of Medicine [Tokyo, Japan]
100 SHGK - SHG Klinikum [Idar-Oberstein, Germany]
101 Institute of Mental Health [Singapore]
102 NIMHANS - National Institute of Mental Health and Neurosciences [Bangalore, Inde]
103 NTNU - Norwegian University of Science and Technology
104 St. Olav's University Hospital - St. Olavs Hospital HF
105 Soviet Psychoneurological Hospital [Urai, Russia]
106 UC San Diego - University of California [San Diego]
107 MCLGH - Makunda Christian Leprosy and General Hospital [Assam, India]
108 University of Tunis El Manar
109 TMHH - Tokyo Metropolitan Hiroo Hospital [Tokyo, Japan]
110 TBF - Tunisian Bipolar Forum [Tunis, Tunisia]
111 Hopital de Razi - Razi Hospital [Tunis]
112 Mahidol University [Bangkok]
113 Siriraj Hospital, Mahidol University
114 Hospital Ángeles del Pedregal [Mexico City, Mexico]
115 Centro Lucio Bini [Cagliari, Italy]
116 Azienda Ospedaliera Sant'Andrea [Roma]
117 UNIROMA - Università degli Studi di Roma "La Sapienza" = Sapienza University [Rome]
118 UO - University of Otago [Christchurch, New Zealand]
119 UDP - Universidad Diego Portales [Santiago - Chili]
120 UCLAN - University of Central Lancashire [Preston]
121 University of Cape Town
122 Stanford School of Medicine [Stanford]
123 ABC - Asha Bipolar Clinic [Hyderabad, Telangana, India]
124 AH - Asha Hospital [Telangana, India]
125 Goethe University Frankfurt
126 University of Iowa [Iowa City]
127 UEFS - Universidade Estadual de Feira de Santana [Bahia]=State University of Feira de Santana
128 SFU - Sigmund Freud University
129 Edin. - University of Edinburgh
130 AREA - Assistance and Research in Affective Disorders [Buenos Aires, Argentina]
131 LaRC - NASA Langley Research Center [Hampton]
132 China Medical University Hospital [Taichung]
133 TCMAH - Tainan City Municipal Annan Hospital [Tainan, Taiwan]
134 Faculty of Medicine, University of Malaya [Kuala Lumpur, Malaisie]
135 Department of Psychiatry [Helsinki]
136 Unhas - Hasanuddin University
137 McLean Hospital [Belmont, Ma.]
138 HMS - Harvard Medical School [Boston]
139 UB - Universitat de Barcelona
140 IDIBAPS - Institut d'Investigacions Biomèdiques August Pi i Sunyer
141 CIBERSAM - Centro de Investigación Biomédica en Red de Salud Mental [Barcelona, Spain]
142 Institute of Psychiatry, Psychology & Neuroscience, King's College London
Michael Bauer
- Fonction : Auteur
- PersonId : 940391
Bruno Etain
- Fonction : Auteur
- PersonId : 757741
- IdHAL : bruno-etain
- ORCID : 0000-0002-5377-1488
- IdRef : 074181106
Ana Gonzalez-Pinto
- Fonction : Auteur
Josselin Houenou
- Fonction : Auteur
- PersonId : 760514
- ORCID : 0000-0003-3166-5606
- IdRef : 078696046
Monica Martinez-Cengotitabengoa
- Fonction : Auteur
Gunnar Morken
- Fonction : Auteur
Arne E Vaaler
- Fonction : Auteur
Résumé
Background: Sunlight contains ultraviolet B (UVB) radiation that triggers the production of vitamin D by skin. Vitamin D has widespread effects on brain function in both developing and adult brains. However, many people live at latitudes (about > 40 N or S) that do not receive enough UVB in winter to produce vitamin D. This exploratory study investigated the association between the age of onset of bipolar I disorder and the threshold for UVB sufficient for vitamin D production in a large global sample.
Methods: Data for 6972 patients with bipolar I disorder were obtained at 75 collection sites in 41 countries in both hemispheres. The best model to assess the relation between the threshold for UVB sufficient for vitamin D production and age of onset included 1 or more months below the threshold, family history of mood disorders, and birth cohort. All coefficients estimated at P ≤ 0.001.
Results: The 6972 patients had an onset in 582 locations in 70 countries, with a mean age of onset of 25.6 years. Of the onset locations, 34.0% had at least 1 month below the threshold for UVB sufficient for vitamin D production. The age of onset at locations with 1 or more months of less than or equal to the threshold for UVB was 1.66 years younger.
Conclusion: UVB and vitamin D may have an important influence on the development of bipolar disorder. Study limitations included a lack of data on patient vitamin D levels, lifestyles, or supplement use. More study of the impacts of UVB and vitamin D in bipolar disorder is needed to evaluate this supposition.
Domaines
Psychiatrie et santé mentale
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