Prevalence of sleep-disordered breathing in a 316-patient French cohort of stable congestive heart failure. - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Archives of cardiovascular diseases Year : 2009

Prevalence of sleep-disordered breathing in a 316-patient French cohort of stable congestive heart failure.

Abstract

BACKGROUND: Heart failure with systolic dysfunction occurs frequently. Studies in North America and Germany have shown a high prevalence of sleep-disordered breathing in patients with heart failure. AIMS: To assess the prevalence of sleep-disordered breathing and its associated risk factors in French patients with heart failure. METHODS: A total of 316patients with stable heart failure and a left ventricular ejection fraction less or equal to 45% underwent polygraphy prospectively to diagnose sleep apnoea syndrome, defined as an apnoea-hypopnoea index greater or equal to 10events/h. RESULTS: Mean age, left ventricular ejection fraction, and body mass index were 59+/-13years, 30+/-11% and 28+/-6kg/m(2), respectively. The prevalence of sleep breathing disorder was 81% (n=256); 30% of syndromes were classified as central and 70% as obstructive. The mean apnoea-hypopnoea index was high (30+/-3events/h) and a large proportion (41%) of syndromes had an apnoea-hypopnoea index greater or equal to 30events/h. A central sleep apnoea syndrome pattern was associated with more severe heart failure and a more elevated apnoea-hypopnoea index than an obstructive pattern. The prevalence of sleep-disordered breathing was lower in women than in men (64% versus 85%; chi(2)=0.0003) as was its severity (mean apnoea-hypopnoea index 15+/-13events/h versus 27+/-19events/h, p=0.0001). CONCLUSION: The prevalence of sleep-disordered breathing was high in a French heart failure population, with most syndromes having an obstructive pattern. Prevalence and severity were higher in men than in women.
Embargoed file
Embargoed file
Visibility date is undetermined
Loading...

Dates and versions

inserm-00387859 , version 1 (26-05-2009)

Identifiers

Cite

Alexandra Paulino, Thibaud Damy, Laurent Margarit, Maria Stoïca, Guillaume Deswarte, et al.. Prevalence of sleep-disordered breathing in a 316-patient French cohort of stable congestive heart failure.. Archives of cardiovascular diseases, 2009, 102 (3), pp.169-75. ⟨10.1016/j.acvd.2008.12.006⟩. ⟨inserm-00387859⟩

Collections

INSERM IMRB UPEC
124 View
0 Download

Altmetric

Share

Gmail Facebook X LinkedIn More