%0 Journal Article %T Prevalence of sleep-disordered breathing in a 316-patient French cohort of stable congestive heart failure. %+ Fédération de cardiologie %+ Institut Mondor de Recherche Biomédicale (IMRB) %+ Service de physiologie, explorations fonctionnelles [Mondor] %+ Service de chirurgie thoracique et cardio-vasculaire [Mondor] %A Paulino, Alexandra %A Damy, Thibaud %A Margarit, Laurent %A Stoïca, Maria %A Deswarte, Guillaume %A Khouri, Latifa %A Vermes, Emmanuelle %A Meizels, Anouk %A Hittinger, Luc %A d'Ortho, Marie-Pia %Z Alexandra Paulino is a recipient of grants from the Frances Dominica Society of Santo Domingo, the Frances Foundation Hospital of Santo Domingo and from Creteil, Paris-12 University. %< avec comité de lecture %@ 1875-2136 %J Archives of cardiovascular diseases %I Elsevier/French Society of Cardiology %V 102 %N 3 %P 169-75 %8 2009-03 %D 2009 %R 10.1016/j.acvd.2008.12.006 %M 19375670 %K Sleep apnoea syndromes %K Prevalence %K Congestive heart failure %Z Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemJournal articles %X BACKGROUND: Heart failure with systolic dysfunction occurs frequently. Studies in North America and Germany have shown a high prevalence of sleep-disordered breathing in patients with heart failure. AIMS: To assess the prevalence of sleep-disordered breathing and its associated risk factors in French patients with heart failure. METHODS: A total of 316patients with stable heart failure and a left ventricular ejection fraction less or equal to 45% underwent polygraphy prospectively to diagnose sleep apnoea syndrome, defined as an apnoea-hypopnoea index greater or equal to 10events/h. RESULTS: Mean age, left ventricular ejection fraction, and body mass index were 59+/-13years, 30+/-11% and 28+/-6kg/m(2), respectively. The prevalence of sleep breathing disorder was 81% (n=256); 30% of syndromes were classified as central and 70% as obstructive. The mean apnoea-hypopnoea index was high (30+/-3events/h) and a large proportion (41%) of syndromes had an apnoea-hypopnoea index greater or equal to 30events/h. A central sleep apnoea syndrome pattern was associated with more severe heart failure and a more elevated apnoea-hypopnoea index than an obstructive pattern. The prevalence of sleep-disordered breathing was lower in women than in men (64% versus 85%; chi(2)=0.0003) as was its severity (mean apnoea-hypopnoea index 15+/-13events/h versus 27+/-19events/h, p=0.0001). CONCLUSION: The prevalence of sleep-disordered breathing was high in a French heart failure population, with most syndromes having an obstructive pattern. Prevalence and severity were higher in men than in women. %G English %2 https://inserm.hal.science/inserm-00387859/document %2 https://inserm.hal.science/inserm-00387859/file/SAS_prevalence_Paulino_ACVD_2009.pdf %L inserm-00387859 %U https://inserm.hal.science/inserm-00387859 %~ INSERM %~ APHP %~ CARDIO %~ IMRB %~ UPEC