[Cranberry (Vaccinium macrocarpon) and urinary tract infections: study model and review of literature] - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Pathologie Biologie Year : 2007

[Cranberry (Vaccinium macrocarpon) and urinary tract infections: study model and review of literature]

Abstract

Cranberries (Vaccinium macrocarpon) have long been the focus of interest for their beneficial effects in preventing urinary tract infections. Among cranberry compounds, a group of proanthocyanidins (PACs) with A-type linkages were isolated which exhibit bacterial anti-adhesion activity against uropathogenic Escherichia coli strains. These PAC inhibit P-fimbriae synthesis and induce a bacterial deformation. This activity was demonstrated on both antibiotic susceptible and resistant bacteria. This review focused on the last discoveries in the knowledge of cranberry effects.
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Dates and versions

inserm-00258570 , version 1 (22-02-2008)

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Jean-Philippe Lavigne, G. Bourg, Henri Botto, Albert Sotto. [Cranberry (Vaccinium macrocarpon) and urinary tract infections: study model and review of literature]. Pathologie Biologie, 2007, 55 (8-9), pp.460-4. ⟨10.1016/j.patbio.2007.07.005⟩. ⟨inserm-00258570⟩
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