Article Dans Une Revue eJHaem Année : 2023

Cerebral localization of chronic myelomonocytic leukemia and improvement with high‐dose cytarabine: A case report

Résumé

Abstract Chronic myelomonocytic leukemia (CMML) is a myelodysplastic/myeloproliferative neoplasm characterized by the infiltration of blood and bone marrow by immature monocytes, in which extra‐hematopoietic localization is uncommon. We report the case of a 69‐year‐old‐man with highly likely ectopic brain CMML involvement by MRI. Without the possibility of cerebral biopsy and with a negative infectious disease assessment, high‐dose cytarabine‐based chemotherapy was successfully administered. The favorable evolution in this case highlights the potential benefit of such treatment, even without a cerebral biopsy to confirm the disease. This case can aid clinical decision‐making in the future.

Dates et versions

inserm-04920440 , version 1 (30-01-2025)

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Citer

Clémence Haméon, Antoine Machet, Laurianne Drieu La Rochelle, Nicolas Vallet, Julien Lejeune, et al.. Cerebral localization of chronic myelomonocytic leukemia and improvement with high‐dose cytarabine: A case report. eJHaem, 2023, 4 (3), pp.844-847. ⟨10.1002/jha2.740⟩. ⟨inserm-04920440⟩
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