Transcriptomic analysis of one patient with lupus skin lesions treated with anifrolumab
Résumé
Transcriptomic analysis of one patient with lupus skin lesions treated with anifrolumab
Dear Editor, Discoid lupus (DLE), a subtype of chronic cutaneous lupus erythematosus (CCLE), is the most common CCLE subtype and presents as erythematous, scaly and atrophic plaques of uncovered skin. CCLE may be refractory to conventional therapies, resulting in major aesthetic damage and representing a therapeutic challenge. The pivotal role of type I interferons (IFN-I) in the pathogenesis of systemic