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Article Dans Une Revue (Article De Synthèse) Hematology Année : 2019

Inflammation in deep vein thrombosis: a therapeutic target?

Résumé

Deep vein thrombosis is a common disease associated with a variety of complications including post-thrombotic syndrome as a late complication. It is now clear that in addition to classical deep vein thrombosis triggers such as blood flow disturbance, hypercoagulability, and vessel wall changes, inflammation has a key role in the pathophysiology of deep vein thrombosis, and there is a close relationship between inflammation and coagulation. As attested by changes in several plasma biomarkers, inflammation may have a significant role in the development of post-thrombotic syndrome. Here, we review the link between inflammation and deep vein thrombosis and thus the potential value of anti-inflammatory and/or anticoagulant drugs in the treatment of deep vein thrombosis and the prevention of post-thrombotic syndrome.
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Origine : Publication financée par une institution
Licence : CC BY - Paternité

Dates et versions

inserm-04455174 , version 1 (13-02-2024)

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Delphine Borgel, Elsa Bianchini, Dominique Lasne, Tiffany Pascreau, François Saller. Inflammation in deep vein thrombosis: a therapeutic target?. Hematology, 2019, 24 (1), pp.742-750. ⟨10.1080/16078454.2019.1687144⟩. ⟨inserm-04455174⟩
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