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Poster De Conférence Année : 2023

The effect of nutritional parameters on the prognosis of childhood interstitial lung diseases

Steve Cunningham
Marijke Proesmans
  • Fonction : Auteur
  • PersonId : 907125
Andy Bushby
  • Fonction : Auteur
  • PersonId : 877121
Ayse Tana Aslan
  • Fonction : Auteur

Résumé

Background-Aim: Data on malnutrition in childhood interstitial lung diseases (chILD) are scarce. We aimed to evaluate malnutrition in chILD and to investigate factors leading to poor nutritional status. Methods: Data source Kids Lung Register. From baseline and follow-up data we analyzed nutritional parameters, severity scores, treatment modalities, PFT data (ppFEV1 and ppFVC) and disease severity (using Fan severity score). Results: Data of 3,334 register visits from 759 children were included. At baseline, 94/759 children (12%) had PEG/fundoplication. For children <2 years, at baseline, malnutrition was present in 144/326 (44%) individuals. Among these children, the most common ILD categories were DPLD: related to alveolar surfactant region (n=38, 26%), growth abnormalities deficient alveolarisation (n=28, 19%), and infant conditions of undefined etiology (n=26, 18%). At one year follow up, malnutrition decreased to 32/144 (22%) children. Disease severity was higher in patients with malnutrition (p<0.001). For children >2 years, at baseline, malnutrition was present in 157/427 (37%) children. The most common ILD categories in these children were DPLD: related to alveolar surfactant region (n=49, 31%), exposures (n=26, 17%), and systemic disease processes (n=26; 17%). At one year follow up, malnutrition decreased to 90/365 (25%) children. Lower ppFEV1 (p<0.001), ppFVC (p<0.001) and disaese severity (p=0.047) were correlated with malnutrition. Conclusion: Malnutrition is common in chILD. Further studies are needed to determine if early nutritional intervention improves the prognosis of patients with child (CRC chILD-EU).

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Dates et versions

inserm-04219720 , version 1 (27-09-2023)

Identifiants

  • HAL Id : inserm-04219720 , version 1

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Nagehan Emiralioglu, Tugba Ramaslı Gursoy, Matthias Griese, Elias Seidl, Nicolaus Schwerk, et al.. The effect of nutritional parameters on the prognosis of childhood interstitial lung diseases. European Respiratory Society, Sep 2023, Milan (Italie), France. ⟨inserm-04219720⟩
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