Adipocyte extracellular vesicles: new rescuers of mitochondrial stress in the heart - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Trends in Endocrinology and Metabolism = Trends in Endocrinology & Metabolism Year : 2022

Adipocyte extracellular vesicles: new rescuers of mitochondrial stress in the heart

Abstract

Nutrient excess induces mitochondrial dysfunction which participates to obesityrelated complications. Obesity also associates with high cardiac oxidative stress that contributes to myocardial dysfunction. Crewe et al. recently evidenced the pivotal role of adipocyte-derived extracellular vesicles in cardiac oxidative stress responses and revealed their unexpected protective effect against ischemia/reperfusion injury.
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inserm-03620375 , version 1 (25-03-2022)

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Xavier Loyer, Chantal Boulanger, Soazig Le Lay. Adipocyte extracellular vesicles: new rescuers of mitochondrial stress in the heart. Trends in Endocrinology and Metabolism = Trends in Endocrinology & Metabolism , 2022, 33 (1), pp.1-3. ⟨10.1016/j.tem.2021.11.001⟩. ⟨inserm-03620375⟩
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