Spastic co-contraction is directly associated with altered cortical beta oscillations after stroke - Inserm - Institut national de la santé et de la recherche médicale Accéder directement au contenu
Article Dans Une Revue Clinical Neurophysiology Année : 2020

Spastic co-contraction is directly associated with altered cortical beta oscillations after stroke

Résumé

Objective: Spastic co-contraction is a motor-disabling form of muscle overactivity occurring after a stroke, contributing to a limitation in active movement and a certain level of motor impairment. The cortical mechanisms underlying spastic co-contraction remain to be more fully elucidated, the present study aimed to investigate the role of the cortical beta oscillations in spastic co-contraction after a stroke. Method: We recruited fifteen post-stroke participants and nine healthy controls. The participants were asked to perform active elbow extensions. In the study, multimodal analysis was performed to combine the evaluation of three-dimensional elbow kinematics, the elbow muscles electromyographic activations, and the cortical oscillatory activity. Results: The movement-related beta desynchronization was significantly decreased in post-stroke participants compared to healthy participants. We found a significant correlation between the movement-related beta desynchronization and the elbow flexors activation during the active elbow extension in post-stroke participants. When compared to healthy participants, post-stroke participants exhibited significant alterations in the elbow kinematics and greater muscle activation levels. Conclusions: Cortical beta oscillation alterations may reflect an important neural mechanism underlying spastic co-contraction after a stroke. Significance: Measuring the cortical oscillatory activity could be useful to further characterize neuromuscular plasticity induced by recovery or therapeutic interventions.
Fichier sous embargo
Fichier sous embargo
Fichier sous embargo
Date de visibilité indéterminée
Fichier sous embargo
Date de visibilité indéterminée

Dates et versions

inserm-03223335 , version 1 (10-05-2021)
inserm-03223335 , version 2 (14-05-2021)

Identifiants

Citer

Alexandre Chalard, David Amarantini, Joseph Tisseyre, Philippe Marque, D. Gasq. Spastic co-contraction is directly associated with altered cortical beta oscillations after stroke. Clinical Neurophysiology, 2020, 131 (6), pp.1345 - 1353. ⟨10.1016/j.clinph.2020.02.023⟩. ⟨inserm-03223335v1⟩
65 Consultations
70 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More