Parafilm-assisted microdissection: a sampling method for mass spectrometry-based identification of differentially expressed prostate cancer protein biomarkers - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Chemical Communications Year : 2015

Parafilm-assisted microdissection: a sampling method for mass spectrometry-based identification of differentially expressed prostate cancer protein biomarkers

Abstract

Mass spectrometry-based methods for prostate cancer biomarker discovery are hampered by their low-throughput capabilities because of extensive sample preparation. We present the parafilm-assisted microdissection technique coupled with label-free quantification and bioinformatics analysis as a means to evaluate directly protein expression changes on benign and tumor regions.
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inserm-02940232 , version 1 (16-09-2020)

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J. Quanico, J. Franck, J. Gimeno, R. Sabbagh, Michel Salzet, et al.. Parafilm-assisted microdissection: a sampling method for mass spectrometry-based identification of differentially expressed prostate cancer protein biomarkers. Chemical Communications, 2015, 51 (22), pp.4564-4567. ⟨10.1039/c4cc08331h⟩. ⟨inserm-02940232⟩
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