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Journal Articles Journal of Experimental Medicine Year : 2020

Switch hitter: Bcl11b in T cells and ILC2s

Abstract

In this issue of JEM, Hosokawa et al. (https://doi-org.proxy.insermbiblio.inist.fr/10.1084/jem.20190972) establish that transcription factor Bcl11b regulates almost completely distinct sets of genes in T cell precursors and ILC2s. To understand how this occurs, they identify multiple levels of functional regulation for Bcl11b that are used differently by T cell precursors and ILC2s.

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Cancer
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Dates and versions

inserm-02541576 , version 1 (14-04-2020)

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Christelle Harly, Avinash Bhandoola. Switch hitter: Bcl11b in T cells and ILC2s. Journal of Experimental Medicine, 2020, 217 (1), pp.e20191739. ⟨10.1084/jem.20191739⟩. ⟨inserm-02541576⟩
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