Switch hitter: Bcl11b in T cells and ILC2s
Abstract
In this issue of JEM, Hosokawa et al. (https://doi-org.proxy.insermbiblio.inist.fr/10.1084/jem.20190972) establish that transcription factor Bcl11b regulates almost completely distinct sets of genes in T cell precursors and ILC2s. To understand how this occurs, they identify multiple levels of functional regulation for Bcl11b that are used differently by T cell precursors and ILC2s.
Domains
Cancer
Origin : Publication funded by an institution
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