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Journal Articles Nanomedicine Year : 2015

Comparative bone tissue integration of nanostructured and microroughened dental implants

Abstract

AIM: The aim was to compare osteointegration of nanostructured implants to a microsurface widely used for titanium dental implants. MATERIALS & METHODS: Commercial titanium dental implants with smooth or microroughened surfaces were nanostructured. Implants were inserted into the femoral condyles of rabbits. After 2 and 4 weeks, histomorphometry calculation was performed. RESULTS: Nanotubes measuring 60 nm in diameter were observed on both S-NANO (roughness: 0.05 μm) and R-NANO (roughness: 0.40 μm) surfaces. The MICRO surface exhibited typical random cavities (roughness: 2.09 μm). At 4 weeks, bone-to-implant contact values were significantly higher for the R-NANO than for the MICRO surface while no differences were observed at 2 weeks. CONCLUSION: Overall, this study shows that the nanostructured surfaces improved osteointegration similar or higher than the MICRO.
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Dates and versions

inserm-01793585 , version 1 (16-05-2018)

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Laëtitia Salou, Alain Hoornaert, Julien Stanovici, Sylvain Briand, Guy Louarn, et al.. Comparative bone tissue integration of nanostructured and microroughened dental implants. Nanomedicine, 2015, 10 (5), pp.741 - 751. ⟨10.2217/NNM.14.223⟩. ⟨inserm-01793585⟩
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