Hidden variant of ChREBP in fat links lipogenesis to insulin sensitivity. - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Cell Metab Year : 2012

Hidden variant of ChREBP in fat links lipogenesis to insulin sensitivity.

Abstract

The ChREBP transcription factor is regulated by glucose and plays a role in insulin sensitivity, but the mechanism underlying these effects remains unclear. In a recent Nature article, Herman et al. (2012) show that a shorter ChREBP isoform (ChREBP-β) links glucose transport to lipogenesis in white adipose tissue.

Dates and versions

inserm-00726503 , version 1 (30-08-2012)

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Renaud Dentin, Dominique Langin, Catherine Postic. Hidden variant of ChREBP in fat links lipogenesis to insulin sensitivity.. Cell Metab, 2012, 15 (6), pp.795-7. ⟨10.1016/j.cmet.2012.05.007⟩. ⟨inserm-00726503⟩
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