Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells. - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles OncoImmunology Year : 2012

Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells.

Abstract

Although primarily defined by their cardinal antigen-presenting function, dendritic cells (DCs) are also equipped with cytotoxic properties. We have recently reported that DCs activated by IFNγ-secreting Th-1 lymphocytes can kill cancer cells and subsequently present the acquired tumor-derived antigens to T lymphocytes both in vitro and in vivo.

Domains

Immunology
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Dates and versions

inserm-00723079 , version 1 (30-06-2013)

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Nicolas Larmonier, Bernard Bonnotte, Emmanuel Katsanis. Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells.. OncoImmunology, 2012, 1 (4), pp.566-568. ⟨10.4161/onci.19370⟩. ⟨inserm-00723079⟩
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