Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand. - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Malaria Journal Year : 2011

Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand.

Bruce Russell
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  • PersonId : 914111
Atis Muehlenbachs
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  • PersonId : 916566
Laurent Rénia
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  • PersonId : 916568
Pratap Singhasivanon
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  • PersonId : 916569

Abstract

Chloroquine (CQ) resistant vivax malaria is spreading. In this case, Plasmodium vivax infections during pregnancy and in the postpartum period were not satisfactorily cleared by CQ, despite adequate drug concentrations. A growth restricted infant was delivered. Poor susceptibility to CQ was confirmed in-vitro and molecular genotyping was strongly suggestive of true recrudescence of P. vivax. This is the first clinically and laboratory confirmed case of two high-grade CQ resistant vivax parasite strains from Thailand.
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Dates and versions

inserm-00654581 , version 1 (22-12-2011)

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Marcus Rijken, Machteld Boel, Bruce Russell, Mallika Imwong, Mara Leimanis, et al.. Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand.. Malaria Journal, 2011, 10 (1), pp.113. ⟨10.1186/1475-2875-10-113⟩. ⟨inserm-00654581⟩
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