Application of click-click chemistry to the synthesis of new multivalent RGD conjugates. - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Organic & Biomolecular Chemistry Year : 2010

Application of click-click chemistry to the synthesis of new multivalent RGD conjugates.

Abstract

New multivalent RGD-containing macromolecules were designed by exploiting two orthogonal chemoselective ligations. They were next applied to a competitive cell adhesion assay and used for the non invasive optical imaging of tumour in small animals.

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Dates and versions

inserm-00559554 , version 1 (25-01-2011)

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Mathieu Galibert, Lucie Sancey, Olivier Renaudet, Jean-Luc Coll, Pascal Dumy, et al.. Application of click-click chemistry to the synthesis of new multivalent RGD conjugates.. Organic & Biomolecular Chemistry, 2010, 8 (22), pp.5133-8. ⟨10.1039/c0ob00070a⟩. ⟨inserm-00559554⟩
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