Synthesis of ferulic ester dimers, functionalisation and biological evaluation as potential antiatherogenic and antiplasmodial agents. - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Bioorganic and Medicinal Chemistry Year : 2007

Synthesis of ferulic ester dimers, functionalisation and biological evaluation as potential antiatherogenic and antiplasmodial agents.

Abstract

Oxidative dimerization of ferulic acid methyl ester afforded dihydrobenzofuran derivative and new linear compound identified by X-ray crystallography. The gallate derivatized dihydrobenzofuran analogue was obtained and all compounds were evaluated for potential antiatherogenic, antiplasmodial (best IC(50)=0.8 microM) and cytotoxic activities.

Dates and versions

inserm-00409724 , version 1 (12-08-2009)

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D. L. A. Rakotondramanana, Mélanie Delomenède, Michel Baltas, Hubert Duran, Florence Bedos-Belval, et al.. Synthesis of ferulic ester dimers, functionalisation and biological evaluation as potential antiatherogenic and antiplasmodial agents.. Bioorganic and Medicinal Chemistry, 2007, 15 (18), pp.6018-26. ⟨10.1016/j.bmc.2007.06.047⟩. ⟨inserm-00409724⟩
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