Production of infectious hepatitis C virus in tissue culture: a breakthrough for basic and applied research. - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Journal of Hepatology Year : 2006

Production of infectious hepatitis C virus in tissue culture: a breakthrough for basic and applied research.

Mirjam B. Zeisel
Thomas F. Baumert
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Abstract

Hepatitis C virus (HCV) is a major cause of posttransfusion and community-acquired hepatitis in the world [1]. The majority of HCV-infected individuals develop chronic hepatitis that may progress to liver cirrhosis and hepatocellular carcinoma. Treatment options for chronic HCV infection are limited and a vaccine to prevent HCV infection is not available [1]. The development of efficient antivirals and a vaccine has been hampered by the lack of an efficient tissue culture model for HCV infection.
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Dates and versions

inserm-00395790 , version 1 (16-06-2009)

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Mirjam B. Zeisel, Thomas F. Baumert. Production of infectious hepatitis C virus in tissue culture: a breakthrough for basic and applied research.. Journal of Hepatology, 2006, 44 (2), pp.436-9. ⟨10.1016/j.jhep.2005.11.031⟩. ⟨inserm-00395790⟩

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