Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients. - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Annales Françaises d'Anesthésie et de Réanimation Year : 2009

Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients.

Abstract

OBJECTIVES: Traumatic brain injury (TBI) is still a major cause of mortality and morbidity. Recent trials have failed to demonstrate a beneficial outcome from therapeutic treatments such as corticosteroids, hypothermia and hypertonic saline. We investigated the effect of a new hyperosmolar solution based on sodium lactate in controlling raised intracranial pressure (ICP). DESIGN AND SETTING: Prospective open randomized study in an adult ICU. PATIENTS: Thirty-four patients with isolated severe TBI (Glasgow Coma Scale

Dates and versions

inserm-00388527 , version 1 (26-05-2009)

Identifiers

Cite

Carole Ichai, Guy Armando, Jean-Christophe Orban, Fréderic Berthier, Laurent Rami, et al.. Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients.. Annales Françaises d'Anesthésie et de Réanimation, 2009, 35 (3), pp.471-9. ⟨10.1007/s00134-008-1283-5⟩. ⟨inserm-00388527⟩

Collections

INSERM UGA LBFA
139 View
0 Download

Altmetric

Share

Gmail Facebook X LinkedIn More