Synthesis of N-(iodophenyl)-amides via an unprecedented Ullmann-Finkelstein tandem reaction
Résumé
Using a new Ullmann-Finkelstein tandem reaction, N-(iodophenyl)-amides were synthesized from the corresponding amides and iodo-bromobenzenes. The catalyst/ligand couple CuI/N,N'-dimethyl-cyclohexane-1,2-diamine was used for this reaction in dioxane with K3PO4 as base.
Domaines
Sciences pharmaceutiques
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