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Récepteurs nucléaires et rythmes circadiens : Implications dans les maladies inflammatoires

Hélène Duez , Benoit Pourcet
Médecine/Sciences, 2022, 38 (8-9), pp.669-678. ⟨10.1051/medsci/2022102⟩
Journal articles hal-03778841v1
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Heterogeneous Effects of Calorie Content and Nutritional Components Underlie Dietary Influence on Pancreatic Cancer Susceptibility

James Dooley , Vasiliki Lagou , Jermaine Goveia , Anna Ulrich , Katerina Rohlenova , et al.
Cell Reports, 2020, 32, pp.107880 -. ⟨10.1016/j.celrep.2020.107880⟩
Journal articles hal-03491313v1
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Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association–European Society of Cardiology

Christoph Maack , Michael Lehrke , Johannes Backs , Frank R Heinzel , Jean-Sebastien Hulot , et al.
European Heart Journal, 2018, 39 (48), pp.4243-4254. ⟨10.1093/eurheartj/ehy596⟩
Journal articles hal-04050735v1

A tool to predict progression of non‐alcoholic fatty liver disease in severely obese patients

Pierre Bauvin , Claire Delacôte , Guillaume Lassailly , Line Carolle Ntandja Wandji , Viviane Gnemmi , et al.
Liver International, 2021, 41 (1), pp.91-100. ⟨10.1111/liv.14650⟩
Journal articles hal-03818871v1

GnRH replacement rescues cognition in Down syndrome

Maria Manfredi-Lozano , Valerie Leysen , Michela Adamo , Isabel Paiva , Renaud Rovera , et al.
Science, 2022, 377 (6610), pp.eabq4515. ⟨10.1126/science.abq4515⟩
Journal articles inserm-03841247v1
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Istradefylline protects from cisplatin-induced nephrotoxicity and peripheral neuropathy while preserving cisplatin antitumor effects

Edmone Dewaeles , Kévin Carvalho , Sandy Fellah , Jaewon Sim , Nihad Boukrout , et al.
The Journal of clinical investigation, 2022, 132 (22), pp.e152924. ⟨10.1172/JCI152924⟩
Journal articles inserm-03865945v1
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Effects of proprotein convertase subtilisin kexin type 9 modulation in human pancreatic beta cells function

Stéphane Ramin-Mangata , Aurélie Thedrez , Brice Nativel , Nicolas Diotel , Valentin Blanchard , et al.
Atherosclerosis, 2021, 326, pp.47-55. ⟨10.1016/j.atherosclerosis.2021.03.044⟩
Journal articles hal-03353494v1
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An unusual left anterior descending artery myocardial bridging

Marjorie Richardson , Guillaume Schurtz , Valentina Silvestri , François Pontana , Gilles Lemesle
Journal of Cardiovascular Computed Tomography, 2020, 14, pp.e78 - e79. ⟨10.1016/j.jcct.2019.05.008⟩
Journal articles hal-03491264v1

Shared genetic predisposition in rheumatoid arthritis-interstitial lung disease and familial pulmonary fibrosis

Pierre-Antoine Juge , Raphaël Borie , Caroline Kannengiesser , Steven Gazal , Patrick Revy , et al.
European Respiratory Journal, 2017, 49 (5), ⟨10.1183/13993003.02314-2016⟩
Journal articles hal-01595463v1

Type I IFN Receptor Signaling Controls IL7-Dependent Accumulation and Activity of Protumoral IL17A-Producing γδT Cells in Breast Cancer

Emmanuel Patin , Daphnée Soulard , Sébastien Fleury , Maya Hassane , David Dombrowicz , et al.
Cancer Research, 2018, 78 (1), pp.195-204. ⟨10.1158/0008-5472.CAN-17-1416⟩
Journal articles inserm-02436039v1
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Farnesoid X Receptor Activation in Brain Alters Brown Adipose Tissue Function via the Sympathetic System

Benjamin Deckmyn , Dorothée Domenger , Chloé Blondel , Sarah Ducastel , Emilie Nicolas , et al.
Frontiers in Molecular Neuroscience, 2022, 14, pp.808603. ⟨10.3389/fnmol.2021.808603⟩
Journal articles inserm-03542610v1

The hypothalamus as a hub for SARS-CoV-2 brain infection and pathogenesis

Sreekala Nampoothiri , Florent Sauve , Gaëtan Ternier , Daniela Fernandois , Caio Coelho , et al.
2021
Preprints, Working Papers, ... hal-03454404v1
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Liver X receptor activation stimulates iron export in human alternative macrophages.

Gael Bories , Sophie Colin , Jonathan Vanhoutte , Bruno Derudas , Corinne Copin , et al.
Circulation Research, 2013, 113 (11), pp.1196-205. ⟨10.1161/CIRCRESAHA.113.301656⟩
Journal articles inserm-00870992v1
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Les lésions de l’endothélium vasculaire

Annabelle Dupont , Mickaël Rosa , Antoine Rauch , Sophie Susen
Médecine/Sciences, 2022, 38 (2), pp.145-147. ⟨10.1051/medsci/2021257⟩
Journal articles hal-03581000v1
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Modulators of hERAP2 discovered by High-Throughput Screening

Laura Medve , Ronan Gealageas , Vy Lam Bao , Valentin Guillaume , Omar Castillo-Aguilera , et al.
European Journal of Medicinal Chemistry, 2020, 211, pp.113053. ⟨10.1016/j.ejmech.2020.113053⟩
Journal articles hal-03059990v1
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Peroxisome proliferator-activated receptor γ regulates genes involved in insulin/insulin-like growth factor signaling and lipid metabolism during adipogenesis through functionally distinct enhancer classes.

Frederik Oger , Julie Dubois-Chevalier , Celine Gheeraert , Stephane Avner , Emmanuel Durand , et al.
Journal of Biological Chemistry, 2014, 289 (2), pp.708-22. ⟨10.1074/jbc.M113.526996⟩
Journal articles inserm-00912805v1
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The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression

Tiffany Fougeray , Arnaud Polizzi , Marion Régnier , Anne Fougerat , Sandrine Ellero-Simatos , et al.
Cell Reports, 2022, 39 (2), pp.110674. ⟨10.1016/j.celrep.2022.110674⟩
Journal articles hal-03647009v1
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NR1D1 controls skeletal muscle calcium homeostasis through myoregulin repression

Alexis Boulinguiez , Christian Duhem , Alicia Mayeuf-Louchart , Benoit Pourcet , Yasmine Sebti , et al.
JCI Insight, 2022, 7 (17), ⟨10.1172/jci.insight.153584⟩
Journal articles hal-03828260v1
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Uncovering the Role of Glycogen in Brown Adipose Tissue

Alicia Mayeuf-Louchart
Pharmaceutical Research, 2021, 38, pp.9-14. ⟨10.1007/s11095-020-02979-6⟩
Journal articles inserm-03121019v1
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Rare causes of hypoglycemia in adults

Claire Douillard , Arnaud Jannin , Marie-Christine Vantyghem
Annales d'Endocrinologie, 2020, 81, pp.110 - 117. ⟨10.1016/j.ando.2020.04.003⟩
Journal articles hal-03490466v1
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CD3(bright) signals on γδ T cells identify IL-17A-producing Vγ6Vδ1(+) T cells.

Christophe Paget , M T Chow , N A Gherardin , P A Beavis , a P Uldrich , et al.
Immunology and Cell Biology, 2015, 93 (2), pp.198-212. ⟨10.1038/icb.2014.94⟩
Journal articles inserm-01116326v1

Lysosomal degradation of newly formed insulin granules contributes to beta cell failure in diabetes

Adrien Pasquier , Kevin Vivot , Eric Erbs , Coralie Spiegelhalter , Zhirong Zhang , et al.
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-11170-4⟩
Journal articles hal-03679172v1
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Hepatic molecular signatures highlight the sexual dimorphism of Non-Alcoholic SteatoHepatitis (NASH)

Jimmy Vandel , Julie Dubois-Chevalier , Celine Gheeraert , Bruno Derudas , Violetta Raverdy , et al.
Hepatology, 2020, ⟨10.1002/HEP.31312⟩
Journal articles inserm-02617094v1
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DNA damage and the activation of the p53 pathway mediate alterations in metabolic and secretory functions of adipocytes Running title: DNA damage and p53 in obese adipocytes

Bastien Vergoni , Pierre-Jean Cornejo , Jérôme Gilleron , Mansour Dedjani , Franck Ceppo , et al.
Diabetes, 2016, 65 (10), pp.3062-3074. ⟨10.2337/db16-0014⟩
Journal articles inserm-01345698v1
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Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants

Alan Hegron , Eunna Huh , Xavier Deupi , Badr Sokrat , Wenwen Gao , et al.
ACS Pharmacology & Translational Science, 2021, 4 (5), pp.1614-1627. ⟨10.1021/acsptsci.1c00157⟩
Journal articles hal-03583044v1
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Non-Alcoholic Steatohepatitis (NASH) and Liver Fibrosis: Molecular and Multicellular Control of Evolving Diseased States

Jérôme Eeckhoute
Cells, 2022, 11 (16), pp.2551. ⟨10.3390/cells11162551⟩
Journal articles hal-03752605v1
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The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

Jan Wenzel , Josephine Lampe , Helge Müller-Fielitz , Raphael Schuster , Marietta Zille , et al.
Nature Neuroscience, 2021, 24 (11), pp.1522-1533. ⟨10.1038/s41593-021-00926-1⟩
Journal articles inserm-03741941v1
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PPAR control of metabolism and cardiovascular functions

David Montaigne , Laura Butruille , Bart Staels
Nature Reviews Cardiology, 2021, Online ahead of print. ⟨10.1038/s41569-021-00569-6⟩
Journal articles inserm-03321273v1
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Preclinical Assessment of Leptin Transport into the Cerebrospinal Fluid in Diet‐Induced Obese Minipigs

Alexandra Chmielewski , Thomas Hubert , Amandine Descamps , Daniele Mazur , Mehdi Daoudi , et al.
Obesity, 2019, 27 (6), pp.950-956. ⟨10.1002/oby.22465⟩
Journal articles inserm-03204359v1
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Acetate Improves the Killing of Streptococcus pneumoniae by Alveolar Macrophages via NLRP3 Inflammasome and Glycolysis-HIF-1α Axis

Marina Gomes Machado , Thiago Andrade Patente , Yves Rouillé , Severine Heumel , Eliza Mathias Melo , et al.
Frontiers in Immunology, 2022, 13, pp.773261. ⟨10.3389/fimmu.2022.773261⟩
Journal articles inserm-03741919v1