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Structure: Internal structure identifier : 39179
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Evaluation of different tests based on observations for external model evaluation of population analyses.

Karl Brendel , Emmanuelle Comets , Céline M. Laffont , France Mentré
Journal of Pharmacokinetics and Pharmacodynamics, 2010, 37 (1), pp.49-65. ⟨10.1007/s10928-009-9143-7⟩
Journal articles inserm-00448559v1
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Optimal sampling times for a drug and its metabolite using SIMCYP(®) simulations as prior information.

Cyrielle Dumont , France Mentré , Clare Gaynor , Karl Brendel , Charlotte Gesson , et al.
Clinical Pharmacokinetics, 2013, 52 (1), pp.43-57. ⟨10.1007/s40262-012-0022-9⟩
Journal articles inserm-00769804v1
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Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide.

Karl Brendel , Emmanuelle Comets , Céline M. Laffont , Christian Laveille , France Mentré
Pharmaceutical Research, 2006, 23 (9), pp.2036-49. ⟨10.1007/s11095-006-9067-5⟩
Journal articles inserm-00189557v1
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Are population pharmacokinetic and/or pharmacodynamic models adequately evaluated? A survey of the literature from 2002 to 2004.

Karl Brendel , Céline Dartois , Emmanuelle Comets , Annabelle Lemenuel-Diot , Christian Laveille , et al.
Clinical Pharmacokinetics, 2007, 46 (3), pp.221-34
Journal articles inserm-00159124v1
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Computing normalised prediction distribution errors to evaluate nonlinear mixed-effect models: The npde add-on package for R.

Emmanuelle Comets , Karl Brendel , France Mentré
Computer Methods and Programs in Biomedicine, 2008, 90 (2), pp.154-66. ⟨10.1016/j.cmpb.2007.12.002⟩
Journal articles inserm-00274332v1
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Why should prediction discrepancies be renamed standardized visual predictive check?

Emmanuelle Comets , Karl Brendel , France Mentré
Journal of Clinical Pharmacology, 2012, 52 (8), pp.1284-5. ⟨10.1177/0091270011412963⟩
Journal articles inserm-00627625v1
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Overview of model-building strategies in population PK/PD analyses: 2002-2004 literature survey.

Céline Dartois , Karl Brendel , Emmanuelle Comets , Céline M. Laffont , Christian Laveille , et al.
British Journal of Clinical Pharmacology, 2007, 64 (5), pp.603-12. ⟨10.1111/j.1365-2125.2007.02975.x⟩
Journal articles inserm-00159122v1