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Synthesis, radiosynthesis and biological evaluation of 1,4-dihydroquinoline derivatives as new carriers for specific brain delivery.
Lénaïg Foucout
,
Fabienne Gourand
,
Martine Dhilly
,
Pierre Bohn
,
Georges Dupas
,
et al.
Journal articles
istex
inserm-00467196v1
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Solid phase synthesis of a redox delivery system with the aim of targeting peptides into the brain.
Claudine Patteux
,
Lénaïg Foucout
,
Pierre Bohn
,
Georges Dupas
,
Jérôme Leprince
,
et al.
Journal articles
istex
inserm-00475858v1
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Rational design of central selective acetylcholinesterase inhibitors by means of a "bio-oxidisable prodrug" strategy.
Pierre Bohn
,
Nicolas Le Fur
,
Guillaume Hagues
,
Jean Costentin
,
Nicolas Torquet
,
et al.
Journal articles
istex
inserm-00467214v1
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Dihydroquinoline Carbamate DQS1-02 as a Prodrug of a Potent Acetylcholinesterase Inhibitor for Alzheimer’s Disease Therapy: Multigram-Scale Synthesis, Mechanism Investigations, in Vitro Safety Pharmacology, and Preliminary in Vivo Toxicology Profile
Florent Alix
,
Vincent Gembus
,
Laurent Coquet
,
Marie Hubert-Roux
,
Philippe Chan
,
et al.
Journal articles
hal-03134333v1
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