Search - Inserm - Institut national de la santé et de la recherche médicale Access content directly

Filter your results

4 Results
authIdHal_s : vincent-levacher

Synthesis, radiosynthesis and biological evaluation of 1,4-dihydroquinoline derivatives as new carriers for specific brain delivery.

Lénaïg Foucout , Fabienne Gourand , Martine Dhilly , Pierre Bohn , Georges Dupas , et al.
Organic & Biomolecular Chemistry, 2009, 7 (18), pp.3666-73. ⟨10.1039/b909650g⟩
Journal articles istex inserm-00467196v1
Image document

Solid phase synthesis of a redox delivery system with the aim of targeting peptides into the brain.

Claudine Patteux , Lénaïg Foucout , Pierre Bohn , Georges Dupas , Jérôme Leprince , et al.
Organic & Biomolecular Chemistry, 2006, 4 (5), pp.817-25. ⟨10.1039/b516737j⟩
Journal articles istex inserm-00475858v1

Rational design of central selective acetylcholinesterase inhibitors by means of a "bio-oxidisable prodrug" strategy.

Pierre Bohn , Nicolas Le Fur , Guillaume Hagues , Jean Costentin , Nicolas Torquet , et al.
Organic & Biomolecular Chemistry, 2009, 7 (12), pp.2612-8. ⟨10.1039/b903041g⟩
Journal articles istex inserm-00467214v1
Image document

Dihydroquinoline Carbamate DQS1-02 as a Prodrug of a Potent Acetylcholinesterase Inhibitor for Alzheimer’s Disease Therapy: Multigram-Scale Synthesis, Mechanism Investigations, in Vitro Safety Pharmacology, and Preliminary in Vivo Toxicology Profile

Florent Alix , Vincent Gembus , Laurent Coquet , Marie Hubert-Roux , Philippe Chan , et al.
ACS Omega, 2018, 3 (12), pp.18387-18397. ⟨10.1021/acsomega.8b02121⟩
Journal articles hal-03134333v1