Search - Inserm - Institut national de la santé et de la recherche médicale Access content directly

Filter your results

15 Results
authIdHal_s : christophe-romier
Image document

The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination

Elizabeth Ramos Morales , Efil Bayam , Jordi del Pozo Rodriguez , Thalia Salinas-Giegé , Martin Marek , et al.
Nucleic Acids Research, 2021, 49 (11), pp.6529-6548. ⟨10.1093/nar/gkab436⟩
Journal articles hal-03282247v1

Automated unrestricted multigene recombineering for multiprotein complex production.

Christoph Bieniossek , Yan Nie , Daniel Frey , Natacha Olieric , Christiane Schaffitzel , et al.
Nature Methods, 2009, 6 (6), pp.447-450. ⟨10.1038/nmeth.1326⟩
Journal articles inserm-00420401v1

Zinc-finger UBPs: regulators of deubiquitylation.

Jacques Bonnet , Christophe Romier , László Tora , Didier Devys
Trends in Biochemical Sciences, 2008, 33 (8), pp.369-75. ⟨10.1016/j.tibs.2008.05.005⟩
Journal articles istex inserm-00311071v1
Image document

Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1

Ehab Ghazy , Patrik Zeyen , Daniel Herp , Martin Hügle , Karin Schmidtkunz , et al.
European Journal of Medicinal Chemistry, 2020, 200, pp.112338. ⟨10.1016/j.ejmech.2020.112338⟩
Journal articles hal-02999300v1
Image document

Characterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly

Benjamin Rothé , Régis Back , Marc Quinternet , Jonathan Bizarro , Marie-Cécile Robert , et al.
Nucleic Acids Research, 2014, 42 (3), pp.2015-2036. ⟨10.1093/nar/gkt1091⟩
Journal articles hal-01452718v1
Image document

Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni

Martin Marek , Srinivasaraghavan Kannan , Alexander-Thomas Hauser , Marina Moraes Mourão , Stéphanie Caby , et al.
PLoS Pathogens, 2013, 9, ⟨10.1371/journal.ppat.1003645⟩
Journal articles hal-03542658v1
Image document

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation

Daniil Alpern , Diana Langer , Benoit Ballester , Stephanie Le Gras , Christophe Romier , et al.
eLife, 2014, 3, pp.308-312. ⟨10.7554/eLife.03613.001⟩
Journal articles hal-01404987v1
Image document

A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing

Conrad Simoben , Dina Robaa , Alokta Chakrabarti , Karin Schmidtkunz , Martin Marek , et al.
Molecules, 2018, 23 (3), pp.566. ⟨10.3390/molecules23030566⟩
Journal articles hal-02391176v1
Image document

Binding Free Energy (BFE) Calculations and Quantitative Structure-Activity Relationship (QSAR) Analysis of Schistosoma mansoni Histone Deacetylase 8 (smHDAC8) Inhibitors

Conrad V. Simoben , Ehab Ghazy , Patrick Zeyen , Salma Darwish , Matthias Schmidt , et al.
Molecules, 2021, 26 (9), ⟨10.3390/molecules26092584⟩
Journal articles hal-03709508v1

Schistosome sirtuins as drug targets

Julien Lancelot , Alejandro Cabezas Cruz , Stéphanie Caby , Martin Marek , Johan Schultz , et al.
Future Medicinal Chemistry, 2015, 7 (6), pp.765-782. ⟨10.4155/fmc.15.24⟩
Journal articles hal-02630766v1
Image document

Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity

Hany S. Ibrahim , Mohamed Abdelsalam , Yanira Zeyn , Mathes Zessin , Al-Hassan Mustafa , et al.
International Journal of Molecular Sciences, 2021, 23 (1), pp.369. ⟨10.3390/ijms23010369⟩
Journal articles hal-03821847v1
Image document

NF-Y recruitment of TFIID, multiple interactions with histone fold TAF(II)s

Mattia Frontini , Carol Imbriano , Alberto Disilvio , Brendan Bell , Alessia Bogni , et al.
Journal of Biological Chemistry, 2002, 277 (8), pp.5841-5848. ⟨10.1074/jbc.M103651200⟩
Journal articles hal-04146335v1

The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.

Zita Nagy , Anne Riss , Christophe Romier , Xavier Le Guezennec , Ashok R. Dongre , et al.
Molecular and Cellular Biology, 2009, 29 (6), pp.1649-60. ⟨10.1128/MCB.01076-08⟩
Journal articles inserm-00370154v1
Image document

Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation

Sébastien Coassolo , Guillaume Davidson , Luc Negroni , Giovanni Gambi , Sylvain Daujat , et al.
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-21960-4⟩
Journal articles hal-03445292v1
Image document

Crystal Structure of a Subcomplex of Human Transcription Factor TFIID Formed by TATA Binding Protein-associated Factors hTAF4 (hTAF II 135) and hTAF12 (hTAF II 20)

Sebastiaan Werten , André Mitschler , Christophe Romier , Yann-Gaël Gangloff , Sylvie Thuault , et al.
Journal of Biological Chemistry, 2002, 277 (47), pp.45502-45509. ⟨10.1074/jbc.M206587200⟩
Journal articles hal-02126927v1