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Dual targeting of BCL2 and MCL1 rescues myeloma cells resistant to BCL2 and MCL1 inhibitors associated with the formation of BAX/ BAK hetero-complexes

Carolane Seiller , Sophie Maiga , Cyrille Touzeau , Céline Bellanger , Charlotte Kervoëlen , et al.
Cell Death and Disease, 2020, 11, pp.316. ⟨10.1038/s41419-020-2505-1⟩
Journal articles inserm-02563554v1
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BH3 profiling as a tool to identify acquired resistance to venetoclax in multiple myeloma

Christelle Dousset , Sophie Maïga , Patricia Gomez-Bougie , Joy Le Coq , Cyrille Touzeau , et al.
British Journal of Haematology, 2016, [Epub ahead of print]. ⟨10.1111/bjh.14251⟩
Journal articles inserm-01353369v1
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Targeting Oxidative Stress With Auranofin or Prima-1Met to Circumvent p53 or Bax/Bak Deficiency in Myeloma Cells

Benoit Tessoulin , Géraldine Descamps , Christelle Dousset , Martine Amiot , Catherine Pellat-Deceunynck
Frontiers in Oncology, 2019, ⟨10.3389/fonc.2019⟩
Journal articles inserm-02055153v1
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Biological rational for sequential targeting of Bruton tyrosine kinase and Bcl-2 to overcome CD40-induced ABT-199 resistance in mantle cell lymphoma

David Chiron , Christelle Dousset , Carole Brosseau , Cyrille Touzeau , Sophie Maïga , et al.
Oncotarget, 2015, 6 (11), pp.8750-9. ⟨10.18632/oncotarget.3275⟩
Journal articles inserm-02534385v1
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Decitabine and Melphalan Fail to Reactivate p73 in p53 Deficient Myeloma Cells

Pierre-Samuel Gillardin , Géraldine Descamps , Sophie Maiga , Benoit Tessoulin , Hanane Djamai , et al.
International Journal of Molecular Sciences, 2017, 19 (1), ⟨10.3390/ijms19010040⟩
Journal articles inserm-01691503v1
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BH3-mimetic toolkit guides the respective use of BCL2 and MCL1 BH3-mimetics in myeloma treatment

Patricia Gomez-Bougie , Sophie Maïga , Benoit Tessoulin , Jessie Bourcier , Antoine Bonnet , et al.
Blood, 2018, Epub ahead of print. ⟨10.1182/blood-2018-03-836718⟩
Journal articles inserm-01900681v1