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Mitochondrial alterations in fatty liver diseases

Bernard Fromenty , Michael Roden
Journal of Hepatology, 2023, 78 (2), pp.415-429. ⟨10.1016/j.jhep.2022.09.020⟩
Journal articles hal-03829001v1

Fat accretion in a subpopulation of hepatocytes as a strategy to protect the whole liver against oxidative stress and lipotoxicity.

Bernard Fromenty
Gastroentérologie Clinique et Biologique / Research and Clinics in Hepatology and Gastroenterology, 2013, 37 (6), pp.553-555. ⟨10.1016/j.clinre.2013.08.005⟩
Journal articles inserm-00869996v1
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Role of Mitochondrial Cytochrome P450 2E1 in Healthy and Diseased Liver

Julie Massart , Karima Begriche , Jessica H Hartman , Bernard Fromenty
Cells, 2022, 11 (2), pp.288. ⟨10.3390/cells11020288⟩
Journal articles hal-03555433v1
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Cocktail de pesticides et stéatose hépatique

Bernard Fromenty
Les cahiers de la Recherche : Santé, Environnement, Travail, 2021, Les contaminants chimiques seuls ou en mélange, 16, pp.44-45
Journal articles anses-03211753v1

Differences in early acetaminophen hepatotoxicity between obese ob/ob and db/db mice.

Jacinthe Aubert , Karima Begriche , Matthieu Delannoy , Isabelle Morel , Julie Pajaud , et al.
Journal of Pharmacology and Experimental Therapeutics, 2012, 342 (3), pp.676-87. ⟨10.1124/jpet.112.193813⟩
Journal articles inserm-00864718v1
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Bisphenol A induces steatosis in HepaRG cells using a model of perinatal exposure

Simon Bucher , Pégah Jalili , Dounia Le Guillou , Karima Begriche , Karine Rondel , et al.
Environmental Toxicology, 2017, 32 (3), pp.1024-1036. ⟨10.1002/tox.22301⟩
Journal articles hal-01470709v1

Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease

Géraldine Gentric , Vanessa Maillet , Valérie Paradis , Dominique Couton , Antoine L’hermitte , et al.
Journal of Clinical Investigation, 2015, 125 (3), pp.981-992. ⟨10.1172/JCI73957⟩
Journal articles inserm-02532139v1
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Role of endoplasmic reticulum stress in drug-induced toxicity

Fabienne Foufelle , Bernard Fromenty
Pharmacology Research & Perspectives, 2016, 4 (1), pp.e00211. ⟨10.1002/prp2.211⟩
Journal articles hal-01269898v1
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Cytochrome P450 2E1 should not be neglected for acetaminophen-induced liver injury in metabolic diseases with altered insulin levels or glucose homeostasis

Julie Massart , Karima Begriche , Bernard Fromenty
Clinics and Research in Hepatology and Gastroenterology, 2021, 45 (1), pp.101470. ⟨10.1016/j.clinre.2020.05.018⟩
Journal articles hal-02899685v1
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Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity

Julien Allard , Simon Bucher , Julie Massart , Pierre-Jean Ferron , Dounia Le Guillou , et al.
Cell Biology and Toxicology, 2021, 37 (2), pp.151-175. ⟨10.1007/s10565-020-09537-1⟩
Journal articles hal-02886702v1

Bridging the gap between old and new concepts in drug-induced liver injury.

Bernard Fromenty
Clinics and Research in Hepatology and Gastroenterology, 2013, 37 (1), pp.6-9. ⟨10.1016/j.clinre.2012.12.003⟩
Journal articles inserm-00808972v1

Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease.

Karima Begriche , Julie Massart , Marie-Anne Robin , Fabrice Bonnet , Bernard Fromenty
Hepatology, 2013, 58 (4), pp.1497-1507. ⟨10.1002/hep.26226⟩
Journal articles inserm-00814080v1
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Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure

Simon Bucher , Dounia Le Guillou , Julien Allard , Gregory Pinon , Karima Begriche , et al.
Oxidative Medicine and Cellular Longevity, 2018, 2018, pp.4396403. ⟨10.1155/2018/4396403⟩
Journal articles hal-01861586v1
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Burn after feeding. An old uncoupler of oxidative phosphorylation is redesigned for the treatment of nonalcoholic fatty liver disease.

Bernard Fromenty
Clinics and Research in Hepatology and Gastroenterology, 2014, 38 (5), pp.545-549. ⟨10.1016/j.clinre.2014.04.013⟩
Journal articles hal-01068679v1
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Chronic exposure to low doses of pharmaceuticals disturbs the hepatic expression of circadian genes in lean and obese mice.

Sébastien Anthérieu , Dounia Le Guillou , Cédric Coulouarn , Karima Begriche , Viviane Trak-Smayra , et al.
Toxicology and Applied Pharmacology, 2014, 276 (1), pp.63-72. ⟨10.1016/j.taap.2014.01.019⟩
Journal articles hal-01057872v1
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Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver.

Karima Begriche , Julie Massart , Marie-Anne Robin , Annie Borgne-Sanchez , Bernard Fromenty
Journal of Hepatology, 2011, 54 (4), pp.773-94. ⟨10.1016/j.jhep.2010.11.006⟩
Journal articles hal-00739371v1