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Contribution of bioinformatics predictions and of functional splicing assays to the interpretation of unclassified variants of the BRCA genes

Jean Christophe Théry , Sophie Krieger , Pascaline Gaildrat , Françoise Révillon , Marie-Pierre Buisine , et al.
European Journal of Human Genetics, 2011, ⟨10.1038/ejhg.2011.100⟩
Journal articles hal-00652134v1
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Worse prognosis of KRAS c.35 G > A mutant metastatic colorectal cancer (MCRC) patients treated with intensive triplet chemotherapy plus bevacizumab (FIr-B/FOx).

Gemma Bruera , Katia Cannita , Daniela Di Giacomo , Aude Lamy , Thierry Frébourg , et al.
BMC Medicine, 2013, 11 (1), pp.59. ⟨10.1186/1741-7015-11-59⟩
Journal articles inserm-00817083v1
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Prognostic value of KRAS genotype in metastatic colorectal cancer (MCRC) patients treated with intensive triplet chemotherapy plus bevacizumab (FIr-B/FOx) according to extension of metastatic disease.

Gemma Bruera , Katia Cannita , Daniela Di Giacomo , Aude Lamy , Giancarlo Troncone , et al.
BMC Medicine, 2012, 10 (1), pp.135. ⟨10.1186/1741-7015-10-135⟩
Journal articles inserm-00764322v1
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Exonic Splicing Mutations Are More Prevalent than Currently Estimated and Can Be Predicted by Using In Silico Tools

Omar Soukarieh , Pascaline Gaildrat , Mohamad Hamieh , Aurélie Drouet , Stéphanie Baert-Desurmont , et al.
PLoS Genetics, 2016, 12 (1), pp.e1005756. ⟨10.1371/journal.pgen.1005756⟩
Journal articles inserm-02160189v1