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Mycobacterial pan-genome analysis suggests important role of plasmids in the radiation of type VII secretion systems

Emilie Dumas , Eva Christina Boritsch , Mathias Vandenbogaert , Ricardo C. Rodriguez de La Vega , Jean-Michel Thiberge , et al.
Genome Biology and Evolution, 2016, 8 (2), pp.387-402. ⟨10.1093/gbe/evw001⟩
Journal articles hal-01291528v1
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Tuberculose : place de la vaccination dans la maîtrise de la maladie

Roland Brosch , Didier Che , Bénédicte Decludt , Pierre Durieux , Joël Gaudelus , et al.
[Rapport de recherche] Institut national de la santé et de la recherche médicale(INSERM). 2004, 281 p., tableaux, graphiques
Reports hal-01570650v1
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Unexpected Genomic and Phenotypic Diversity of Mycobacterium africanum Lineage 5 Affects Drug Resistance, Protein Secretion, and Immunogenicity

Louis S. Ates , Anzaan Dippenaar , Fadel Sayes , Alexandre Pawlik , Christiane Bouchier , et al.
Genome Biology and Evolution, 2018, 10 (8), pp.1858 - 1874. ⟨10.1093/gbe/evy145⟩
Journal articles hal-01884644v1
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Horizontal acquisition of a hypoxia-responsive molybdenum cofactor biosynthesis pathway contributed to Mycobacterium tuberculosis pathoadaptation

Florence Levillain , Yannick Poquet , Ludovic Mallet , Serge Mazeres , Michael Marceau , et al.
PLoS Pathogens, 2017, 13 (11), pp.e1006752. ⟨10.1371/journal.ppat.1006752⟩
Journal articles hal-01708481v1
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Colonization with Helicobacter is concomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis

Laleh Majlessi , Fadel Sayes , Jean-François Bureau , Alexandre Pawlik , Valérie Michel , et al.
Mucosal Immunology, 2017, 10 (5), pp.1178 - 1189. ⟨10.1038/mi.2016.140⟩
Journal articles hal-01652031v1
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Pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence

Eva C. Boritsch , Wafa Frigui , Alessandro Cascioferro , Wladimir Malaga , Gilles Etienne , et al.
Nature Microbiology, 2016, 1 (février 2016), ⟨10.1038/nmicrobiol.2015.19⟩
Journal articles pasteur-01265519v1
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Parallel in vivo experimental evolution reveals that increased stress resistance was key for the emergence of persistent tuberculosis bacilli

Aideen C Allen , Wladimir Malaga , Cyril Gaudin , Arnaud Volle , Flavie Moreau , et al.
Nature Microbiology, 2021, 6 (8), pp.1082-1093. ⟨10.1038/s41564-021-00938-4⟩
Journal articles hal-03318178v1
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Ancient origin and gene mosaicism of the progenitor of Mycobacterium tuberculosis.

M Cristina Gutierrez , Sylvain Brisse , Roland Brosch , Michel Fabre , Bahia Omaïs , et al.
PLoS Pathogens, 2005, 1, pp.e5. ⟨10.1371/journal.ppat.0010005⟩
Journal articles inserm-00080315v1
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CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection

Fadel Sayes , Alexandre Pawlik , Wafa Frigui , Matthias I Gröschel , Samuel Crommelynck , et al.
PLoS Pathogens, 2016, 12 (7), pp.e1005770. ⟨10.1371/journal.ppat.1005770⟩
Journal articles pasteur-02615226v1
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Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts

Mickael Orgeur , Wafa Frigui , Alexandre Pawlik , Simon Clark , Ann Williams , et al.
Microbial Genomics, 2021, 7 (2), ⟨10.1099/mgen.0.000505⟩
Journal articles pasteur-03255655v1

Insights into the smooth-to-rough transitioning in Mycobacterium bolletii unravels a functional Tyr residue conserved in all mycobacterial MmpL family members

Audrey Bernut , Albertus Viljoen , Christian Dupont , Guillaume Sapriel , Mickaël Blaise , et al.
Molecular Microbiology, 2016, 99 (5), pp.866-883. ⟨10.1111/mmi.13283⟩
Journal articles hal-02137603v1
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Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP.

Wafa Frigui , Daria Bottai , Laleh Majlessi , Marc Monot , Emmanuelle Josselin , et al.
PLoS Pathogens, 2008, 4 (2), pp.e33. ⟨10.1371/journal.ppat.0040033⟩
Journal articles pasteur-01370872v1
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Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo

Roxane Simeone , Fadel Sayes , Okryul Song , Matthias I Gröschel , Priscille Brodin , et al.
PLoS Pathogens, 2015, 11 (2), pp.e1004650. ⟨10.1371/journal.ppat.1004650⟩
Journal articles pasteur-02615223v1
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High Content Phenotypic Cell-Based Visual Screen Identifies Mycobacterium tuberculosis Acyltrehalose-Containing Glycolipids Involved in Phagosome Remodeling

Priscille Brodin , Yannick Poquet , Florence Levillain , Isabelle Peguillet , Gerald Larrouy-Maumus , et al.
PLoS Pathogens, 2010, 6 (9), pp.e1001100. ⟨10.1371/journal.ppat.1001100⟩
Journal articles hal-02902031v1
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A re-evaluation of M. prototuberculosis": continuing the debate.

Sylvain Brisse , Philip Supply , Roland Brosch , Veronique Vincent , M Cristina Gutierrez
PLoS Pathogens, 2006, 2 (9), pp.e95. ⟨10.1371/journal.ppat.0020095⟩
Journal articles pasteur-00146923v1
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Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death

Roxane Simeone , Alexandre Bobard , Juliane Lippmann , Wilbert Bitter , Laleh Majlessi , et al.
PLoS Pathogens, 2012, 8 (2), pp.e1002507. ⟨10.1371/journal.ppat.1002507⟩
Journal articles pasteur-01899479v1
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Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli

Wladimir Malaga , Delphine Payros , Eva Meunier , Wafa Frigui , Fadel Sayes , et al.
PLoS Pathogens, 2023, 19 (7), pp.e1011437. ⟨10.1371/journal.ppat.1011437⟩
Journal articles hal-04163557v1
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Genome-wide mosaicism within Mycobacterium abscessus: evolutionary and epidemiological implications

Guillaume Sapriel , Julie Konjek , Mickael Orgeur , Laurent Bouri , Lise Frézal , et al.
BMC Genomics, 2016, 17 (1), pp.118. ⟨10.1186/s12864-016-2448-1⟩
Journal articles hal-01284527v1

Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system

Daria Bottai , Wafa Frigui , Simon Clark , Emma Rayner , Andrea Zelmer , et al.
Vaccine, 2015, 33 (23), pp.2710-2718. ⟨10.1016/j.vaccine.2015.03.083⟩
Journal articles pasteur-01182937v1

ESAT-6 Secretion-Independent Impact of ESX-1 Genes espF and espG1 on Virulence of Mycobacterium tuberculosis

Daria Bottai , Laleh Majlessi , Roxane Simeone , Wafa Frigui , Christine Laurent , et al.
Journal of Infectious Diseases, 2011, 203 (8), pp.1155-1164. ⟨10.1093/infdis/jiq089⟩
Journal articles pasteur-02862998v1
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A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity

Jodie Lopez , François Anna , Pierre Authié , Alexandre Pawlik , Min-Wen Ku , et al.
Cell Reports, 2022, 40 (4), pp.111142. ⟨10.1016/j.celrep.2022.111142⟩
Journal articles pasteur-03909608v1