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authFullName_s : Sandrine Silvente-Poirot

Molecular characterization of the microsomal tamoxifen binding site.

Blandine Kedjouar , Philippe de Médina , Mustapha Oulad-Abdelghani , Bruno Payré , Sandrine Silvente-Poirot , et al.
Journal of Biological Chemistry, 2004, 279, pp.34048-61. ⟨10.1074/jbc.M405230200⟩
Journal articles inserm-00090773v1
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Dendrogenin A Enhances Anti-Leukemic Effect of Anthracycline in Acute Myeloid Leukemia

Pierre-Luc Mouchel , Nizar Serhan , Rémy Bétous , Thomas Farge , Estelle Saland , et al.
Cancers, 2020, 12 (10), pp.2933. ⟨10.3390/cancers12102933⟩
Journal articles inserm-03084630v1

Vitamin E: an overview

Farid Khallouki , Robert Wyn Owen , Mourad Akdad , Bachir El Bouhali , Sandrine Silvente-Poirot , et al.
Molecular Nutrition, Elsevier, pp.51-66, 2020, ⟨10.1016/B978-0-12-811907-5.00001-4⟩
Book sections inserm-03084874v1

Surprising unreactivity of cholesterol-5,6-epoxides towards nucleophiles.

Michael R. Paillasse , Nathalie Saffon , Heinz Gornitzka , Sandrine Silvente-Poirot , Marc Poirot , et al.
Journal of Lipid Research, 2012, 53 (4), pp.718-25. ⟨10.1194/jlr.M023689⟩
Journal articles inserm-00743457v1

Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion.

Michael R. Paillasse , Philippe de Médina , Guillaume Amouroux , Loubna Mhamdi , Marc E. Poirot , et al.
Journal of Lipid Research, 2009, 50 (11), pp.2203-11. ⟨10.1194/jlr.M800668-JLR200⟩
Journal articles inserm-00519146v1

Insights into the cholecystokinin 2 receptor binding site and processes of activation.

Michaël Paillasse , Céline Deraeve , Philippe de Médina , Loubna Mhamdi , Gilles Favre , et al.
Molecular Pharmacology, 2006, 70 (6), pp.1935-45. ⟨10.1124/mol.106.029967⟩
Journal articles inserm-00519168v1
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The tumor-suppressor cholesterol metabolite, dendrogenin A, is a new class of LXR modulator activating lethal autophagy in cancers

Sandrine Silvente-Poirot , Marc Poirot
Biochemical Pharmacology, 2018, 153, pp.75-81. ⟨10.1016/j.bcp.2018.01.046⟩
Journal articles inserm-02380575v1
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Is cholesterol a risk factor for breast cancer incidence and outcome?

Céline Ben Hassen , Caroline Goupille , Claire Vigor , Thierry Durand , Françoise Guéraud , et al.
Journal of Steroid Biochemistry and Molecular Biology, In press, pp.106346. ⟨10.1016/j.jsbmb.2023.106346⟩
Journal articles hal-04165228v1
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Circulating oxysterol metabolites as potential new surrogate markers in patients with hormone receptor-positive breast cancer: Results of the OXYTAM study

Florence Dalenc , Luiggi Iuliano , Thomas Filleron , Chiara Zerbinati , Maud Voisin , et al.
Journal of Steroid Biochemistry and Molecular Biology, 2017, 169, pp.210-218. ⟨10.1016/j.jsbmb.2016.06.010⟩
Journal articles inserm-02380620v1
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Molecular and Biochemical Analysis of the Estrogenic and Proliferative Properties of Vitamin E Compounds

Farid Khallouki , Philippe de Médina , Stéphanie Caze-Subra , Kerstin Bystricky , Patrick Balaguer , et al.
Frontiers in Oncology, 2016, 5, ⟨10.3389/fonc.2015.00287⟩
Journal articles hal-02271824v1
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HPLC Analysis and Skin Whitening Effects of Umbelliprenin-containing Extracts of Anethum Graveolens, Pimpinella Anisum, and Ferulago Campestris

Vito Taddeo , Francesco Epifano , Francesca Preziuso , Serena Fiorito , Nicolas Caron , et al.
Molecules, 2019, 24 (3), pp.501. ⟨10.3390/molecules24030501⟩
Journal articles inserm-02380544v1
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Extracellular vesicles: lipids as key components of their biogenesis and functions

Michel Record , Sandrine Silvente-Poirot , Marc Poirot , Michael J. O. Wakelam
Journal of Lipid Research, 2018, 59 (8), pp.1316-1324. ⟨10.1194/jlr.E086173⟩
Journal articles inserm-02380557v1
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Quantitative analysis of the tumor suppressor dendrogenin A using liquid chromatography tandem mass spectrometry

Emmanuel Noguer , Régis Soules , Claude Netter , Citra Nagarathinam , Julie Leignadier , et al.
Chemistry and Physics of Lipids, 2017, 207, pp.81-86. ⟨10.1016/j.chemphyslip.2017.06.010⟩
Journal articles inserm-02380602v1
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Improvement of 5,6α-epoxycholesterol, 5,6β-epoxycholesterol, cholestane-3β,5α,6β-triol and 6-oxo-cholestan-3β,5α-diol recovery for quantification by GC/MS

Régis Soules , Emmanuel Noguer , Luigi Iuliano , Chiara Zerbinati , Julie Leignadier , et al.
Chemistry and Physics of Lipids, 2017, 207, pp.92-98. ⟨10.1016/j.chemphyslip.2017.05.006⟩
Journal articles inserm-02380612v1

The novel steroidal alkaloids dendrogenin A and B promote proliferation of adult neural stem cells.

Shaden A. M. Khalifa , Philippe de Médina , Anna Erlandsson , Hesham R. El-Seedi , Sandrine Silvente-Poirot , et al.
Biochemical and Biophysical Research Communications, 2014, 446 (3), pp.681-6. ⟨10.1016/j.bbrc.2013.12.134⟩
Journal articles inserm-00968932v1

Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies.

Michel Record , Kevin Carayon , Marc Poirot , Sandrine Silvente-Poirot
BBA - Biochimica et Biophysica Acta, 2014, 1841 (1), pp.108-20. ⟨10.1016/j.bbalip.2013.10.004⟩
Journal articles inserm-00968935v1
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Improving the efficacy of hormone therapy in breast cancer: The role of cholesterol metabolism in SERM-mediated autophagy, cell differentiation and death

Julie Leignadier , Florence Dalenc , Marc Poirot , Sandrine Silvente-Poirot
Biochemical Pharmacology, 2017, 144, pp.18-28. ⟨10.1016/j.bcp.2017.06.120⟩
Journal articles inserm-02380608v1

Tamoxifen is a potent inhibitor of cholesterol esterification and prevents the formation of foam cells.

Philippe de Médina , Bruno Payré , José Bernad , Isabelle Bosser , Bernard Pipy , et al.
J Pharmacol Exp Ther, 2004, 308, pp.1165-73. ⟨10.1124/jpet.103.060426⟩
Journal articles inserm-00090774v1

High tumorigenic potential of a constitutively active mutant of the cholecystokinin 2 receptor.

Céline Galés , Didier Sanchez , Marc E. Poirot , Stéphane Pyronnet , Louis Buscail , et al.
Oncogene, 2003, 22, pp.6081-9. ⟨10.1038/sj.onc.1206823⟩
Journal articles inserm-00090775v1

Identification of tyrosine 189 and asparagine 358 of the cholecystokinin 2 receptor in direct interaction with the crucial C-terminal amide of cholecystokinin by molecular modeling, site-directed mutagenesis, and structure/affinity studies.

Céline Galés , Marc E. Poirot , Julien Taillefer , Bernard Maigret , Jean Martinez , et al.
Molecular Pharmacology, 2003, 63, pp.973-82
Journal articles inserm-00090776v1

Tamoxifen and AEBS ligands induced apoptosis and autophagy in breast cancer cells through the stimulation of sterol accumulation.

Philippe de Médina , Sandrine Silvente-Poirot , Marc E. Poirot
Autophagy, 2009, 5 (7), pp.1066-7
Journal articles inserm-00519150v1

Auraptene is an inhibitor of cholesterol esterification and a modulator of estrogen receptors.

Philippe de Médina , Salvatore Genovese , Michael R. Paillasse , Mahta Mazaheri , Stephanie Subra-Caze , et al.
Molecular Pharmacology, 2010, epub ahead of print. ⟨10.1124/mol.110.065250⟩
Journal articles inserm-00519166v1
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Oxysterols: An expanding family of structurally diversified bioactive steroids

Marc Poirot , Sandrine Silvente-Poirot
Journal of Steroid Biochemistry and Molecular Biology, 2019, 194, pp.105443. ⟨10.1016/j.jsbmb.2019.105443⟩
Journal articles inserm-02380490v1
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The Effects of Cholesterol-Derived Oncometabolites on Nuclear Receptor Function in Cancer

Sandrine Silvente-Poirot , Florence Dalenc , Marc Poirot
Cancer Research, 2018, 78 (17), pp.4803-4808. ⟨10.1158/0008-5472.CAN-18-1487⟩
Journal articles inserm-02380586v1

Dendrogenin A: A Mammalian Metabolite of Cholesterol with Tumor Suppressor and Neurostimulating Properties

Florence Dalenc , Marc Poirot , Sandrine Silvente-Poirot
Current Medicinal Chemistry, 2015, 22 (30), pp.3533-3549. ⟨10.2174/0929867322666150716114912⟩
Journal articles inserm-02380776v1

Cholesterol metabolism and cancer: the good, the bad and the ugly.

Sandrine Silvente-Poirot , Marc Poirot
Current Opinion in Pharmacology, 2012, 12 (6), pp.673-6. ⟨10.1016/j.coph.2012.10.004⟩
Journal articles istex inserm-00822284v1

Importance of cholesterol and oxysterols metabolism in the pharmacology of tamoxifen and other AEBS ligands.

Philippe de Médina , Michael R. Paillasse , Gregory Ségala , Farid Khallouki , Severine Brillouet , et al.
Chemistry and Physics of Lipids, 2011, 164 (6), pp.432-7. ⟨10.1016/j.chemphyslip.2011.05.005⟩
Journal articles istex inserm-00743454v1

Cholesterol epoxide hydrolase and cancer.

Sandrine Silvente-Poirot , Marc Poirot
Current Opinion in Pharmacology, 2012, 12 (6), pp.696-703. ⟨10.1016/j.coph.2012.07.007⟩
Journal articles istex inserm-00743463v1

The prototypical inhibitor of cholesterol esterification, Sah 58-035 is an agonist of estrogen receptors.

Philippe de Médina , Nadia Boubekeur , Patrick Balaguer , Gilles Favre , Sandrine Silvente-Poirot , et al.
J Pharmacol Exp Ther, 2006, 319, pp.139. ⟨10.1124/jpet.106.104349⟩
Journal articles inserm-00090770v1

Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor

Maud Voisin , Philippe de Médina , Arnaud Mallinger , Florence Dalenc , Emilie Huc-Claustre , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (44), pp.E9346-E9355. ⟨10.1073/pnas.1707965114⟩
Journal articles hal-02316171v1