Search - Inserm - Institut national de la santé et de la recherche médicale Access content directly

Filter your results

40 Results
authFullName_s : Pierre-Louis Tharaux
Image document

Deletion of the myeloid endothelin-B receptor confers long-term protection from angiotensin II-mediated kidney, eye and vessel injury

Léa Guyonnet , Alicja Czopek , Tariq E Farrah , Véronique Baudrie , Philippe Bonnin , et al.
Kidney International, 2020, 98 (5), pp.1193-1209. ⟨10.1016/j.kint.2020.05.042⟩
Journal articles hal-03268543v1

Vascular endothelin-1 gene expression and synthesis and effect on renal type I collagen synthesis and nephroangiosclerosis during nitric oxide synthase inhibition in rats.

Pierre-Louis Tharaux , Daniel Casellas
Circulation, 1999, 99, pp.2185-91
Journal articles inserm-00000114v1

Urinary endothelin-1 as a marker of renal damage in sickle cell disease.

Pierre-Louis Tharaux , Robert Girot , Alain Kanfer
Nephrology Dialysis Transplantation, 2005, 20, pp.2408-13. ⟨10.1093/ndt/gfi111⟩
Journal articles inserm-00000115v1

Severe COVID-19 is associated with hyperactivation of the alternative complement pathway

Jeremy Boussier , Nader Yatim , Armance Marchal , Jérôme Hadjadj , Bruno Charbit , et al.
Journal of Allergy and Clinical Immunology, 2022, 149 (2), pp.550-556.e2. ⟨10.1016/j.jaci.2021.11.004⟩
Journal articles pasteur-03477606v1
Image document

Angiotensin II Activates Collagen Type I Gene in the Renal Vasculature of Transgenic Mice During Inhibition of Nitric Oxide Synthesis

Jean-Jacques Boffa , Pierre-Louis Tharaux , Sandrine Placier , Raymond Ardaillou , Jean-Claude Dussaule , et al.
Circulation, 1999, 100 (18), pp.1901-1908. ⟨10.1161/01.cir.100.18.1901⟩
Journal articles inserm-03788594v1
Image document

Direct Action of Endothelin-1 on Podocytes Promotes Diabetic Glomerulosclerosis

Olivia Lenoir , Marine Milon , Anne Virsolvy , Carole Henique , Alain Schmitt , et al.
Journal of the American Society of Nephrology, 2014, 25 (5), pp.1050-1062. ⟨10.1681/ASN.2013020195⟩
Journal articles hal-02542297v1
Image document

L’hypertension artérielle maligne , un futur prometteur

Romain Boulestreau , Antoine Cremer , Aurelien Lorthioir , Sébastien Rubin , Pierre-Louis Tharaux , et al.
La Presse Médicale, 2019, 48 (12), pp.1439-1444. ⟨10.1016/j.lpm.2019.07.007⟩
Journal articles hal-03117380v1
Image document

Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort

Raphael Carapito , Richard Li , Julie Helms , Christine Carapito , Sharvari Gujja , et al.
Science Translational Medicine, 2021, pp.1-59. ⟨10.1126/scitranslmed.abj7521⟩
Journal articles hal-03436053v1

Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial

Pierre-Louis Tharaux , Gilles Pialoux , Arthur Pavot , Xavier Mariette , Olivier Hermine , et al.
The Lancet Respiratory Medicine, 2021, 9 (3), pp.295-304. ⟨10.1016/S2213-2600(20)30556-7⟩
Journal articles hal-03579180v1

MicroRNAs in kidney injury and disease

Nassim Mahtal , Olivia Lenoir , Claire Tinel , Dany Anglicheau , Pierre-Louis Tharaux
Nature Reviews Nephrology, 2022, 18 (10), pp.643-662. ⟨10.1038/s41581-022-00608-6⟩
Journal articles inserm-03787575v1
Image document

Endothelial Epas1 Deficiency Is Sufficient To Promote Parietal Epithelial Cell Activation and FSGS in Experimental Hypertension

Yosu Luque , Olivia Lenoir , Philippe Bonnin , Lise Hardy , Anna Chipont , et al.
Journal of the American Society of Nephrology, 2017, 28 (12), pp.3563-3578. ⟨10.1681/ASN.2016090960⟩
Journal articles hal-01713482v1
Image document

Cardiac Metabolic Deregulation Induced by the Tyrosine Kinase Receptor Inhibitor Sunitinib is rescued by Endothelin Receptor Antagonism

Joevin Sourdon , Franck Lager , Thomas Viel , Daniel Balvay , Rebecca Moorhouse , et al.
Theranostics, 2017, 7 (11), pp.2757-2774. ⟨10.7150/thno.19551⟩
Journal articles inserm-02439089v1
Image document

Second harmonic imaging and scoring of collagen in fibrotic tissues.

Mathias Strupler , Ana-Maria Pena , Monica Hernest , Pierre-Louis Tharaux , Jean-Louis Martin , et al.
Optics Express, 2007, 15 (7), pp.4054-4065. ⟨10.1364/OE.15.004054⟩
Journal articles hal-00824058v1
Image document

Sunitinib-induced cardiac hypertrophy and the endothelin axis

Joevin Sourdon , Caterina Facchin , Anaïs Certain , Thomas Viel , Blaise Robin , et al.
Theranostics, 2021, 11, pp.3830 - 3838. ⟨10.7150/thno.49837⟩
Journal articles hal-03430957v1
Image document

The proteome of neutrophils in sickle cell disease reveals an unexpected activation of interferon alpha signaling pathway

Patricia Hermand , Slim Azouzi , Emilie-Fleur Gautier , François Guillonneau , Vincent Bondet , et al.
Haematologica, 2020, pp.haematol.2019.238295. ⟨10.3324/haematol.2019.238295⟩
Journal articles pasteur-02505633v1
Image document

A novel role for myeloid endothelin-B receptors in hypertension

Alicja Czopek , Rebecca Moorhouse , Léa Guyonnet , Tariq Farrah , Olivia Lenoir , et al.
European Heart Journal, 2019, 40 (9), pp.768-784. ⟨10.1093/eurheartj/ehy881⟩
Journal articles inserm-02439065v1

Should we consider calcimimetics as a therapeutic option for nephrotic syndrome?

Olivia Lenoir , Pierre-Louis Tharaux
Kidney International, 2022, 101 (6), pp.1110-1112. ⟨10.1016/j.kint.2022.04.008⟩
Journal articles inserm-03788305v1

FIBER-ML, an Open-Source Supervised Machine Learning Tool for Quantification of Fibrosis in Tissue Sections

Caterina Facchin , Anais Certain , Thulaciga Yoganathan , Clement Delacroix , Alicia Arevalo Garcia , et al.
American Journal of Pathology, 2022, 192 (5), pp.783-793. ⟨10.1016/j.ajpath.2022.01.013⟩
Journal articles inserm-03788337v1
Image document

Glomerular Endothelial Cell Crosstalk With Podocytes in Diabetic Kidney Disease

Nassim Mahtal , Olivia Lenoir , Pierre-Louis Tharaux
Frontiers in Medicine, 2021, 8, pp.659013. ⟨10.3389/fmed.2021.659013⟩
Journal articles inserm-03788342v1

Podocyte healthy self-eating boosted by a spermidine meal?

Olivia Lenoir , Pierre-Louis Tharaux
Kidney International, 2020, 98 (6), pp.1390-1392. ⟨10.1016/j.kint.2020.07.032⟩
Journal articles inserm-03788350v1
Image document

Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis

Carole Henique , Guillaume Bollée , Xavier Loyer , Florian F. Grahammer , Neeraj Dhaun , et al.
Nature Communications, 2017, 8 (1), pp.1829. ⟨10.1038/s41467-017-01885-7⟩
Journal articles inserm-02439029v1

Selective EGF-Receptor Inhibition in CD4+ T Cells Induces Anergy and Limits Atherosclerosis

Lynda Zeboudj , Mikael Maître , Léa Guyonnet , Ludivine Laurans , Jérémie Joffre , et al.
Journal of the American College of Cardiology, 2018, 71 (2), pp.160-172. ⟨10.1016/j.jacc.2017.10.084⟩
Journal articles hal-02402850v1
Image document

Tocilizumab plus dexamethasone versus dexamethasone in patients with moderate-to-severe COVID-19 pneumonia: A randomised clinical trial from the CORIMUNO-19 study group

Olivier Hermine , Xavier Mariette , Raphael Porcher , Felix Djossou , Yann Nguyen , et al.
EClinicalMedicine, 2022, 46, pp.101362. ⟨10.1016/j.eclinm.2022.101362⟩
Journal articles inserm-03787576v1
Image document

Effect of interleukin-6 receptor antagonists in critically ill adult patients with COVID-19 pneumonia: two randomised controlled trials of the CORIMUNO-19 Collaborative Group

Olivier Hermine , Xavier Mariette , Raphael Porcher , Matthieu Resche-Rigon , Pierre-Louis Tharaux , et al.
European Respiratory Journal, 2022, 60 (2), pp.2102523. ⟨10.1183/13993003.02523-2021⟩
Journal articles inserm-03787577v1
Image document

Nuclear Factor Erythroid 2-Related Factor 2 Drives Podocyte-Specific Expression of Peroxisome Proliferator-Activated Receptor γ Essential for Resistance to Crescentic GN

Carole Henique , Guillaume Bollee , Olivia Lenoir , Neeraj Dhaun , Marine Camus , et al.
Journal of the American Society of Nephrology, 2015, 27 (1), pp.172-188. ⟨10.1681/ASN.2014111080⟩
Journal articles inserm-03788642v1

Endothelial S1P 1 Signaling Counteracts Infarct Expansion in Ischemic Stroke

Anja Nitzsche , Marine Poittevin , Ammar Benarab , Philippe Bonnin , Giuseppe Faraco , et al.
Circulation Research, 2021, 128 (3), pp.363-382. ⟨10.1161/CIRCRESAHA.120.316711⟩
Journal articles hal-03886183v1
Image document

Rôle pathogénique de l’expression anormale de la tétraspanine CD9 par les cellules épithéliales pariétales dans les glomérulopathies extracapillaires

Hélène Lazareth , Olivia Lenoir , Carole Hénique , Cédric Bouzigues , Claude Boucheix , et al.
Médecine/Sciences, 2020, 36 (10), pp.852-855. ⟨10.1051/medsci/2020154⟩
Journal articles hal-02960790v1
Image document

Angiotensin II Activates Collagen I Gene Through a Mechanism Involving the MAP/ER Kinase Pathway

Pierre-Louis Tharaux , Christos Chatziantoniou , Fadi Fakhouri , Jean-Claude Dussaule
Hypertension, 2000, 36 (3), pp.330-336. ⟨10.1161/01.hyp.36.3.330⟩
Journal articles inserm-03788595v1
Image document

The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression

Hélène Lazareth , Carole Henique , Olivia Lenoir , Victor Puelles , Martin Flamant , et al.
Nature Communications, 2019, 10 (1), pp.3303. ⟨10.1038/s41467-019-11013-2⟩
Journal articles inserm-02439082v1
Image document

Posttranslational modifications of sickle hemoglobin in microparticles may promote injury

Pierre-Louis Tharaux
Kidney International, 2019, 95, pp.1289 - 1291. ⟨10.1016/j.kint.2019.02.023⟩
Journal articles hal-03477636v1