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authFullName_s : Hinrich Gronemeyer
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Genome-wide studies of nuclear receptors in cell fate decisions.

Marco-Antonio Mendoza-Parra , Hinrich Gronemeyer
Seminars in Cell and Developmental Biology, 2013, 24 (10-12), pp.706-15. ⟨10.1016/j.semcdb.2013.07.001⟩
Journal articles inserm-00854329v1

Highly potent naphthofuran-based retinoic acid receptor agonists.

Efrén Pérez Santín , Harshal Khanwalkar , Johannes J. Voegel , Pascal Collette , Pascale Mauvais , et al.
ChemMedChem, 2009, 4 (5), pp.780-91. ⟨10.1002/cmdc.200900015⟩
Journal articles inserm-00384552v1

Growth factor-antagonized rexinoid apoptosis involves permissive PPARgamma/RXR heterodimers to activate the intrinsic death pathway by NO.

Pattabhiraman Shankaranarayanan , Aurélie Rossin , Harshal Khanwalkar , Susana Alvarez , Rosana Alvarez , et al.
Cancer Cell, 2009, 16 (3), pp.220-31. ⟨10.1016/j.ccr.2009.07.029⟩
Journal articles inserm-00420821v1

TRAIL: at the center of drugable anti-tumor pathways

Nicole Clarke , Angela Nebbioso , Lucia Altucci , Hinrich Gronemeyer
Cell Cycle, 2005, 4 (7), pp.914-918. ⟨10.4161/cc.4.7.1822⟩
Journal articles hal-04142402v1

Retinoid receptor subtype-selective modulators through synthetic modifications of RARgamma agonists.

Susana Alvarez , Rosana Alvarez , Harshal Khanwalkar , Pierre Germain , Géraldine Lemaire , et al.
Bioorganic and Medicinal Chemistry, 2009, 17 (13), pp.4345-59. ⟨10.1016/j.bmc.2009.05.035⟩
Journal articles istex inserm-00420402v1

Synthesis and pharmacological characterization of Disila-AM80 (Disila-tamibarotene) and Disila-AM580, silicon analogues of the RARalpha-selective retinoid agonists AM80 (Tamibarotene) and AM580.

Reinhold Tacke , Volker Müller , Matthias W. Büttner , W Peter Lippert , Rüdiger Bertermann , et al.
ChemMedChem, 2009, 4 (11), pp.1797-802. ⟨10.1002/cmdc.200900257⟩
Journal articles istex inserm-00438709v1
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An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor β (RARβ, NR1B2) Selective Agonist

Eswarkumar Nadendla , Catherine Teyssier , Vanessa Delfosse , Valérie Vivat , Gunasekaran Krishnasamy , et al.
PLoS ONE, 2015, 10 (5), pp.e0123195. ⟨10.1371/journal.pone.0123195⟩
Journal articles hal-02273910v1

Decryption of the retinoid death code in leukemia

Lucia Altucci , Hinrich Gronemeyer
Journal of Clinical Immunology, 2002, 22 (3), pp.117-123. ⟨10.1023/a:1015490627613⟩
Journal articles istex hal-04130437v1

Fingering modulators of retinoic acid signaling identifies new prognostic marker for neuroblastoma.

Hinrich Gronemeyer , Arthur Zelent
Cancer Cell, 2009, 15 (4), pp.249-51. ⟨10.1016/j.ccr.2009.03.012⟩
Journal articles inserm-00384302v1
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Retinoic acid protects human breast cancer cells against etoposide-induced apoptosis by NF-kappaB-dependent but cIAP2-independent mechanisms.

Ana Jiménez-Lara , Ana Aranda , Hinrich Gronemeyer
Molecular Cancer, 2010, 9 (1), pp.15. ⟨10.1186/1476-4598-9-15⟩
Journal articles inserm-00668473v1

Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells

Yelyzaveta Shlyakhtina , Valeria Pavet-Portal , Hinrich Gronemeyer
Cell Death and Disease, 2017, 8 (8), ⟨10.1038/cddis.2017.423⟩
Journal articles hal-03677786v1

Cloning of a mouse glucocorticoid modulatory element binding protein, a new member of the KDWK family

Ana M. Jimenez-Lara , Matthias J. S. Heine , Hinrich Gronemeyer
FEBS Letters, 2000, 468 (2-3), pp.203-210. ⟨10.1016/s0014-5793(00)01209-6⟩
Journal articles hal-04094343v1

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

Lorenzo Galluzzi , Stuart A. Aaronson , John Abrams , Emad S Alnemri , David W. Andrews , et al.
Cell Death and Differentiation, 2009, 16 (8), pp.1093-107. ⟨10.1038/cdd.2009.44⟩
Journal articles inserm-00420382v1

Leukemia: beneficial actions of retinoids and rexinoids

Lucia Altucci , Emmanuelle Wilhelm , Hinrich Gronemeyer
International Journal of Biochemistry and Cell Biology, 2004, 36 (2), pp.178-182. ⟨10.1016/s1357-2725(03)00247-4⟩
Journal articles istex hal-04130441v1

9-cis-retinoic acid analogues with bulky hydrophobic rings: new RXR-selective agonists

Rosana Alvarez , M. Jesús Vega , Sabrina Kammerer , Aurélie Rossin , Pierre Germain , et al.
Bioorganic & Medicinal Chemistry Letters, 2004, 14 (24), pp.6117-6122. ⟨10.1016/j.bmcl.2004.08.072⟩
Journal articles istex hal-04122966v1

The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways

Johannes J. Voegel , Matthias J. Heine , Marc Tini , Valérie Vivat , Pierre Chambon , et al.
EMBO Journal, 1998, 17 (2), pp.507-519. ⟨10.1093/emboj/17.2.507⟩
Journal articles hal-04057107v1

The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP

Martine Gehin , Manuel Mark , Christine Dennefeld , Andrée Dierich , Hinrich Gronemeyer , et al.
Molecular and Cellular Biology, 2002, 22 (16), pp.5923-5937. ⟨10.1128/MCB.22.16.5923-5937.2002⟩
Journal articles hal-04145149v1

Conformational adaptation of agonists to the human nuclear receptor RAR gamma

Bruno P. Klaholz , Jean-Paul Renaud , André Mitschler , C. Zusi , Pierre Chambon , et al.
Nature Structural Biology, 1998, 5 (3), pp.199-202. ⟨10.1038/nsb0398-199⟩
Journal articles istex hal-04017111v1

Epimetheus - a multi-profile normalizer for epigenomic sequencing data

Mohamed Ashick Mohamed Saleem , Marco Antonio Mendoza Parra , Pierre Cholley , Matthias Blum , Hinrich Gronemeyer
BMC Bioinformatics, 2017, 18 (1), ⟨10.1186/s12859-017-1655-3⟩
Journal articles hal-03677828v1

Differential action on coregulator interaction defines inverse retinoid agonists and neutral antagonists.

Pierre Germain , Claudine Gaudon , Vivian Pogenberg , Sarah Sanglier , Alain van Dorsselaer , et al.
Chemistry and Biology, 2009, 16 (5), pp.479-89. ⟨10.1016/j.chembiol.2009.03.008⟩
Journal articles inserm-00420381v1

Inference from RNA interference: Suggestions to our authors

Hinrich Gronemeyer
International Journal of Cancer, 2020, 146 (1), ⟨10.1002/ijc.32641⟩
Journal articles hal-03665614v1

C3 halogen and c8'' substituents on stilbene arotinoids modulate retinoic Acid receptor subtype function.

Susana Alvarez , Harshal Khanwalkar , Rosana Alvarez , Cathie Erb , Claudio Martínez , et al.
ChemMedChem, 2009, 4 (10), pp.1630-40. ⟨10.1002/cmdc.200900214⟩
Journal articles inserm-00438635v1

The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation

Ann-Sofie Brier , Anne Loft , Jesper Madsen , Thomas Rosengren , Ronni Nielsen , et al.
Nucleic Acids Research, 2017, 45 (4), pp.1743-1759. ⟨10.1093/nar/gkw1156⟩
Journal articles hal-03677803v1

Reconstruction of gene regulatory networks reveals chromatin remodelers and key transcription factors in tumorigenesis

Valeriya Malysheva , Marco Antonio Mendoza Parra , Mohamed Ashick Mohamed Saleem , Hinrich Gronemeyer
Genome Medicine, 2016, 8 (1), ⟨10.1186/s13073-016-0310-3⟩
Journal articles hal-03686927v1

Versatile copurification procedure for rapid isolation of homogeneous RAR-RXR heterodimers

Jaya Iyer , Dominique Bonnier , Florence Granger , Carole Peluso-Iltis , Virginie Andry , et al.
Protein Expression and Purification, 1999, 16 (2), pp.308-314. ⟨10.1006/prep.1999.1053⟩
Journal articles istex hal-04057119v1

Allosteric effects govern nuclear receptor action: DNA appears as a player.

Hinrich Gronemeyer , William Bourguet
Science Signaling, 2009, 2 (73), pe34. ⟨10.1126/scisignal.273pe34⟩
Journal articles inserm-00420377v1
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Patient-matched analysis identifies deregulated networks in prostate cancer to guide personalized therapeutic intervention

Akinchan Kumar , Yasenya Kasikci , Alaa Badredine , Karim Azzag , Marie L Quintyn Ranty , et al.
American Journal of Cancer Research, 2021, 11 (11), pp.5299-5318. ⟨10.1101/695999⟩
Journal articles hal-03473404v1

The nuclear receptor ligand-binding domain: structure and function

Dino Moras , Hinrich Gronemeyer
Current Opinion in Cell Biology, 1998, 10 (3), pp.384-391. ⟨10.1016/s0955-0674(98)80015-x⟩
Journal articles istex hal-04057134v1

Silicon analogues of the RXR-selective retinoid agonist SR11237 (BMS649): chemistry and biology.

W Peter Lippert , Christian Burschka , Kathrin Götz , Martin Kaupp , Diana Ivanova , et al.
ChemMedChem, 2009, 4 (7), pp.1143-52. ⟨10.1002/cmdc.200900090⟩
Journal articles inserm-00420365v1
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Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes.

Angela Nebbioso , Fabio Manzo , Marco Miceli , Mariarosaria Conte , Lucrezia Manente , et al.
EMBO Reports, 2009, 10 (7), pp.776-82. ⟨10.1038/embor.2009.88⟩
Journal articles inserm-00420167v1