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authFullName_s : Christophe Orvain
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Multifunctional Compounds for Activation of the p53-Y220C Mutant in Cancer

Jessica Miller , Christophe Orvain , Shireen Jozi , Ryan Clarke , Jason Smith , et al.
Chemistry - A European Journal, 2018, 24 (67), pp.17734-17742. ⟨10.1002/chem.201802677⟩
Journal articles inserm-02364129v1
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Ultrasound and Transcriptomics Identify a Differential Impact of Cisplatin and Histone Deacetylation on Tumor Structure and Microenvironment in a Patient-Derived In Vivo Model of Gastric Cancer

Aina Venkatasamy , Eric Guerin , Anais Blanchet , Christophe Orvain , Véronique Devignot , et al.
Pharmaceutics, 2021, 13 (9), pp.1485. ⟨10.3390/pharmaceutics13091485⟩
Journal articles hal-03450657v1
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Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action

Maria Babak , Martin Pfaffeneder-Kmen , Samuel Meier-Menches , Maria Legina , Sarah Theiner , et al.
Inorganic Chemistry, 2018, 57 (5), pp.2851-2864. ⟨10.1021/acs.inorgchem.7b03210⟩
Journal articles inserm-02364163v1
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Expression and functional studies of the GDNF family receptor alpha 3 in the pancreas

Laure Nivlet , Joel Herrmann , Delia Esteban Martin , Aline Meunier , Christophe Orvain , et al.
Journal of Molecular Endocrinology, 2016, 56 (2), pp.77-90. ⟨10.1530/JME-15-0213⟩
Journal articles inserm-03455716v1
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Bifunctional ligand design for modulating mutant p53 aggregation in cancer

Jessica Miller , Anaïs Blanchet , Christophe Orvain , Lucienne Nouchikian , Yasmin Reviriot , et al.
Chemical Science, 2019, Epub ahead of print. ⟨10.1039/c9sc04151f⟩
Journal articles inserm-02364138v1
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HDAC4 Levels Control Sensibility toward Cisplatin in Gastric Cancer via the p53-p73/BIK Pathway

Marie-Elodie Spaety , Alexandre Gries , Amandine Badie , Aina Venkatasamy , Benoît Romain , et al.
Cancers, 2019, 11 (11), pp.1747. ⟨10.3390/cancers11111747⟩
Journal articles inserm-02363213v1
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Gold(III) to Ruthenium(III) Metal Exchange in Dithiocarbamato Complexes Tunes Their Biological Mode of Action for Cytotoxicity in Cancer Cells

Maria Dalla Pozza , Christophe Orvain , Leonardo Brustolin , Nicolò Pettenuzzo , Chiara Nardon , et al.
Molecules, 2021, 26 (13), pp.4073. ⟨10.3390/molecules26134073⟩
Journal articles hal-03450763v1
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Trans-C versus Cis-C thermally induced isomerisation of a terpyridine adduct of cytotoxic cycloruthenated compound

Moussa Ali , Adel Hamada , Houda Habbita , Jennifer Weckbach , Christophe Orvain , et al.
Journal of Organometallic Chemistry, 2017, 845, pp.206-212. ⟨10.1016/j.jorganchem.2017.05.022⟩
Journal articles inserm-02365254v1
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Impact of cyclometalated ruthenium(II) complexes on lactate dehydrogenase activity and cytotoxicity in gastric and colon cancer cells

Hugo Rico Bautista , Rafael Omar Saavedra Díaz , Longzhu Shen , Christophe Orvain , Christian Gaiddon , et al.
Journal of Inorganic Biochemistry, 2016, 163, pp.28-38. ⟨10.1016/j.jinorgbio.2016.07.014⟩
Journal articles inserm-02365314v1