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Essential fatty acids deficiency promotes lipogenic gene expression and hepatic steatosis through the liver X receptor.
Simon Ducheix
,
Alexandra Montagner
,
Arnaud Polizzi
,
Frédéric Lasserre
,
Alice Marmugi
,
et al.
Journal articles
inserm-00872314v1
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Novel Grb14-Mediated Cross Talk between Insulin and p62/Nrf2 Pathways Regulates Liver Lipogenesis and Selective Insulin Resistance
Lucie Popineau
,
Lucille Morzyglod
,
Nadege Carre
,
Michele Cauzac
,
Pascale Bossard
,
et al.
Journal articles
hal-01602453v1
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The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity
Julien Bricambert
,
Marie-Clotilde Alves-Guerra
,
Pauline Esteves
,
Carina Prip-Buus
,
Justine Bertrand-Michel
,
et al.
Journal articles
hal-02122655v1
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Interaction between Hormone-Sensitive Lipase and ChREBP in Fat Cells Controls Insulin Sensitivity
Pauline Morigny
,
Marianne Houssier
,
Aline Mairal
,
Claire Ghilain
,
Etienne Mouisel
,
et al.
Journal articles
inserm-02150261v1
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O-GlcNAcylation links ChREBP and FXR to glucose-sensing
Fadila Benhamed
,
Gaelle Filhoulaud
,
Sandrine Caron
,
Philippe Lefebvre
,
Bart Staels
,
et al.
Journal articles
inserm-01103380v1
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New targets for NAFLD
Lucia Parlati
,
Marion Régnier
,
Hervé Guillou
,
Catherine Postic
Journal articles
hal-03472343v1
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Growth factor receptor binding protein 14 inhibition triggers insulin-induced mouse hepatocyte proliferation and is associated with hepatocellular carcinoma
Lucille Morzyglod
,
Michèle Caüzac
,
Lucie Popineau
,
Pierre-Damien Denechaud
,
Lluis Fajas
,
et al.
Journal articles
hal-01606970v1
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Matrix metalloproteinase 11 protects from diabesity and promotes metabolic switch
Nassim Dali-Youcef
,
Karim Hnia
,
Sébastien Blaise
,
Nadia Messaddeq
,
Stéphane Blanc
,
et al.
Journal articles
inserm-01322791v1
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Hepatic Gene Regulation by Glucose and Polyunsaturated Fatty Acids: A Role for ChREBP
Renaud Dentin
,
Pierre-Damien Denechaud
,
Fadila Benhamed
,
Jean Girard
,
Catherine Postic
Journal articles
hal-03144767v1
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Insulin resistance per se drives early and reversible dysbiosis-mediated gut barrier impairment and bactericidal dysfunction
Dalale Gueddouri
,
Michèle Caüzac
,
Véronique Fauveau
,
Fadila Benhamed
,
Wafa Charifi
,
et al.
Journal articles
hal-03555418v1
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The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression
Tiffany Fougeray
,
Arnaud Polizzi
,
Marion Régnier
,
Anne Fougerat
,
Sandrine Ellero-Simatos
,
et al.
Journal articles
hal-03647009v1
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Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes
Amar Abderrahmani
,
Loïc Yengo
,
Robert Caiazzo
,
Mickael Canouil
,
Stéphane Cauchi
,
et al.
Journal articles
hal-01837153v1
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Monoacylglycerol lipase reprograms hepatocytes and macrophages to promote liver regeneration
Manon Allaire
,
Rola Al-Sayegh
,
Morgane Mabire
,
Adel Hammoutene
,
Matthieu Siebert
,
et al.
Journal articles
hal-04178833v1
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Cross-regulation of hepatic glucose metabolism ChREBP and Nuclear Receptors
Audrey Poupeau
,
Catherine Postic
Journal articles
hal-00706532v1
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Rôle des hépatokines dans le dialogue inter-organes en physiologie et physiopathologie
Aude Pacheco
,
Catherine Postic
Journal articles
hal-03491047v1
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Adipocyte Glucocorticoid Receptor Deficiency Promotes Adipose Tissue Expandability and Improves the Metabolic Profile Under Corticosterone Exposure
Héloïse Dalle
,
Marie Garcia
,
Bénédicte Antoine
,
Vanessa Boehm
,
Thi Thu Huong Do
,
et al.
Journal articles
hal-02348048v1
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UCP2 silencing restrains leukemia cell proliferation through glutamine metabolic remodeling
Tiphaine Sancerni
,
Ophélie Renoult
,
Angèle Luby
,
Cédric Caradeuc
,
Véronique Lenoir
,
et al.
Journal articles
hal-03817349v1
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ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity
Anne Fougerat
,
Gabriele Schoiswohl
,
Arnaud Polizzi
,
Marion Régnier
,
Carina Wagner
,
et al.
Journal articles
hal-03695833v1
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Hidden variant of ChREBP in fat links lipogenesis to insulin sensitivity.
Renaud Dentin
,
Dominique Langin
,
Catherine Postic
Journal articles
inserm-00726503v1
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O -GlcNAcylation Increases ChREBP Protein Content and Transcriptional Activity in the Liver
Céline Guinez
,
Gaëlle Filhoulaud
,
Fadila Rayah-Benhamed
,
Solenne Marmier
,
Céline Dubuquoy
,
et al.
Journal articles
hal-04000900v1
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Le facteur de transcription ChREBP
Fadila Benhamed
,
Audrey Poupeau
,
Catherine Postic
Journal articles
hal-03144760v1
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Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD
Alexandra Montagner
,
Arnaud Polizzi
,
Edwin Fouché
,
Simon Ducheix
,
Yannick Lippi
,
et al.
Journal articles
inserm-02339685v1
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Dual regulation of TxNIP by ChREBP and FoxO1 in liver
Bénédicte Noblet
,
Fadila Benhamed
,
Insug O-Sullivan
,
Wenwei Zhang
,
Gaelle Filhoulaud
,
et al.
Journal articles
hal-03176271v1
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Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target
Sarra Smati
,
Arnaud Polizzi
,
Anne Fougerat
,
Sandrine Ellero-Simatos
,
Yuna Blum
,
et al.
Journal articles
hal-03215969v1
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Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity
Marion Régnier
,
Arnaud Polizzi
,
Sarra Smati
,
Céline Lukowicz
,
Anne Fougerat
,
et al.
Journal articles
inserm-02875414v1
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Insulin activates hepatic Wnt/β- catenin signaling through stearoyl- CoA desaturase 1 and Porcupine
Régine Cabrae
,
Céline Dubuquoy
,
Michèle Caüzac
,
Lucille Morzyglod
,
Sandra Guilmeau
,
et al.
Journal articles
inserm-02537243v1
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The absence of hepatic glucose-6 phosphatase/ChREBP couple is incompatible with survival in mice.
Fabienne Rajas
,
Renaud Dentin
,
Alexane Cannella
,
Marine Silva
,
Margaux Raffin
,
et al.
Journal articles
inserm-03038399v1
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O-GlcNacylation Links TxNIP to Inflammasome Activation in Pancreatic β Cells
Gaelle Filhoulaud
,
Fadila Benhamed
,
Patrick Pagesy
,
Caroline Bonner
,
Yann Fardini
,
et al.
Journal articles
hal-02196741v1
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Farnesoid X receptor inhibits the transcriptional activity of carbohydrate response element binding protein in human hepatocytes.
Sandrine Caron
,
Carolina Huaman Samanez
,
Hélène Dehondt
,
Maheul Ploton
,
Olivier Briand
,
et al.
Journal articles
inserm-00806064v1
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