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First-in-Human Study in Healthy Subjects with FR104, a Pegylated Monoclonal Antibody Fragment Antagonist of CD28
Nicolas Poirier
,
Gilles Blancho
,
Maryvonne Hiance
,
Caroline Mary
,
Tim Van Assche
,
et al.
Journal articles
inserm-02150993v1
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Interleukin‐7 receptor blockade by an anti‐ CD 127 monoclonal antibody in nonhuman primate kidney transplantation
Hoa Le Mai
,
Thi van Ha Nguyen
,
Julien Branchereau
,
Nicolas Poirier
,
Karine Renaudin
,
et al.
Journal articles
inserm-02337117v1
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SIRP α/CD 47 axis controls the maintenance of transplant tolerance sustained by myeloid‐derived suppressor cells
Sabrina Pengam
,
Justine Durand
,
Claire Usal
,
Vanessa Gauttier
,
Nahzli Dilek
,
et al.
Journal articles
inserm-02336708v1
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IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates
Lyssia Belarif
,
Caroline Mary
,
Lola Jacquemont
,
Hoa Le Mai
,
Richard Danger
,
et al.
Journal articles
inserm-02023397v1
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Selective SIRPα blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance
Vanessa Gauttier
,
Sabrina Pengam
,
Justine Durand
,
Kevin Biteau
,
Caroline Mary
,
et al.
Journal articles
hal-03001660v1
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Targeting CD28, CTLA-4 and PD-L1 Costimulation Differentially Controls Immune Synapses and Function of Human Regulatory and Conventional T-Cells
Nahzli Dilek
,
Nicolas Poirier
,
Philippe Hulin
,
Flora Coulon
,
Caroline Mary
,
et al.
Journal articles
inserm-02165637v1
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CLEC-1 is a death sensor that limits antigen cross-presentation by dendritic cells and represents a target for cancer immunotherapy
Marion Drouin
,
Javier Saenz
,
Vanessa Gauttier
,
Berangere Evrard
,
Geraldine Teppaz
,
et al.
Journal articles
inserm-04003975v1
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A selective CD28 antagonist and rapamycin synergise to protect against spontaneous autoimmune diabetes in NOD mice
Alix Besancon
,
Tania Goncalves
,
Fabrice Valette
,
Caroline Mary
,
Bernard Vanhove
,
et al.
Journal articles
hal-01881129v1
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Anti-CD28 Antibody and Belatacept Exert Differential Effects on Mechanisms of Renal Allograft Rejection
Simon Ville
,
Nicolas Poirier
,
Julien Branchereau
,
Vianney Charpy
,
Sabrina Pengam
,
et al.
Journal articles
inserm-02150329v1
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SIRPγ-CD47 Interaction Positively Regulates the Activation of Human T Cells in Situation of Chronic Stimulation
Safa Dehmani
,
Véronique Nerrière-Daguin
,
Mélanie Néel
,
Nathan Elain-Duret
,
Jean-Marie Heslan
,
et al.
Journal articles
inserm-03627808v1
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Evaluation of FR104, a Treg sparing antagonist anti-CD28 monovalent Fab' antibody in kidney transplantation in non-human primates
Nicolas Poirier
,
Nahzli Dilek
,
Caroline Mary
,
Jeremy Hervouet
,
David Minault
,
et al.
7th European Workshop on Immune-Mediated Inflammatory Diseases, Nov 2012, Netherlands. pp.P61
Conference papers
inserm-00758213v1
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Selective CD28 Antagonist Blunts Memory Immune Responses and Promotes Long-Term Control of Skin Inflammation in Nonhuman Primates
Nicolas Poirier
,
Melanie Chevalier
,
Caroline Mary
,
Jérémy Hervouet
,
David Minault
,
et al.
Journal articles
inserm-02150299v1
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IL-7 receptor influences anti-TNF responsiveness and T cell gut homing in inflammatory bowel disease
Lyssia Belarif
,
Richard Danger
,
Laetitia Kermarrec
,
Véronique Nerrière-Daguin
,
Sabrina Pengam
,
et al.
Journal articles
inserm-02145888v1
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CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates
Benjamin K. Watkins
,
Victor Tkachev
,
Scott N. Furlan
,
Daniel J. Hunt
,
Kayla Betz
,
et al.
Journal articles
inserm-02157599v1
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Prevention of lupus nephritis development in NZB/NZW mice by selective blockade of CD28
Laetitia Laurent
,
Awena Le Fur
,
Rozenn Le Bloas
,
Mélanie Néel
,
Caroline Mary
,
et al.
Journal articles
inserm-02155317v1
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Selective CD28 antagonist prevents Aldara-induced skin inflammation in non-human primates
Nicolas Poirier
,
Mélanie Chevalier
,
Caroline Mary
,
Jérémy Hervouet
,
David Minault
,
et al.
Journal articles
inserm-02150253v1
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Selective Blockade of CD28-Mediated T Cell Costimulation Protects Rhesus Monkeys against Acute Fatal Experimental Autoimmune Encephalomyelitis
Krista G Haanstra
,
Karin Dijkman
,
Noun Bashir
,
Jan Bauer
,
Caroline Mary
,
et al.
Journal articles
inserm-02148517v1
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Graft versus host disease in humanized mice is differentially controlled by CD28 and CD80/86 antagonists
Nicolas Poirier
,
Nahzli Dilek
,
Caroline Mary
,
Bernard Vanhove
7th European Workshop on Immune-Mediated Inflammatory Diseases, Nov 2012, Netherlands. pp.O2
Conference papers
inserm-00758217v1
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Triggering the resolution of inflammation with agonistic anti-ChemR23 antibody dampens inflammation-driven carcinogenesis and metastasis
Vanessa Gauttier
,
Margot Lavy
,
Charlène Trilleaud
,
Kévin Biteau
,
Stéphanie Neyton
,
et al.
American Association for Cancer Researc 2021, 2021, Virtual Meeting, United States
Conference poster
inserm-03349406v1
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