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authFullName_s : Agnès Quéméner
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Prevalence, biological phenotype and genotype in moderate/ mild hemophilia A with discrepancy between one-stage and chromogenic factor VIII activity

Marc Trossaert , Pierre Boisseau , Agnès Quéméner , Marianne Sigaud , Marc Fouassier , et al.
Journal of Thrombosis and Haemostasis, 2011, 9 (3), pp.524-530. ⟨10.1111/j.1538-7836.2010.04174.x⟩
Journal articles inserm-02441164v1
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Soluble Interleukin-15 Receptor α (IL-15Rα)-sushi as a Selective and Potent Agonist of IL-15 Action through IL-15Rβ/γ HYPERAGONIST IL-15.IL-15Rα FUSION PROTEINS

Erwan Mortier , Agnès Quéméner , Patricia Vusio , Inken Lorenzen , Yvan Boublik , et al.
Journal of Biological Chemistry, 2006, 281 (3), pp.1612. ⟨10.1074/jbc.M508624200⟩
Journal articles inserm-02442379v1
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Tumor targeting of the IL-15 superagonist RLI by an anti-GD2 antibody strongly enhances its antitumor potency

Marie Vincent , Anne Bessard , Denis Cochonneau , Géraldine Teppaz , Véronique Solé , et al.
International Journal of Cancer, 2013, ⟨10.1002/ijc.28059⟩
Journal articles inserm-02440732v1
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Evolution of interleukin-15 for higher E. coli expression and solubility

Ghislaine Béhar , Véronique Sole , Alain Defontaine , Mike Maillasson , Agnès Quéméner , et al.
Protein Engineering, Design and Selection, 2011, 24 (3), pp.283-290. ⟨10.1093/protein/gzq107⟩
Journal articles inserm-02442555v1
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Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity

Catherine Rabu , Agnès Quéméner , Yannick Jacques , Klara Echasserieau , Patricia Vusio , et al.
Journal of Biological Chemistry, 2005, 280, pp.41472 - 41481. ⟨10.1074/jbc.M506881200⟩
Journal articles inserm-02442588v1
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IL-15Rα membrane-anchorage either in cis or in trans is required for stabilization of IL-15 and optimal signaling

Agnès Quéméner , Sébastien Morisseau , Rui P Sousa , Kilian Trillet , Mike Maillasson , et al.
Journal of Cell Science, 2019, Epub ahead of print. ⟨10.1242/jcs.236802⟩
Journal articles inserm-02345095v1
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Identification of an Interleukin-15 α Receptor-binding Site on Human Interleukin-15

Jérôme Bernard , Catherine Harb , Erwan Mortier , Agnès Quéméner , Rob H Meloen , et al.
Journal of Biological Chemistry, 2004, 279 (23), pp.24313. ⟨10.1074/jbc.M312458200⟩
Journal articles inserm-02442410v1
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Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization

Agnès Quéméner , Mike Maillasson , Laurence Arzel , Benoit Sicard , Romy Vomiandry , et al.
Journal of Medicinal Chemistry, 2017, 60 (14), pp.6249-6272. ⟨10.1021/acs.jmedchem.7b00485⟩
Journal articles inserm-01550121v1
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Counteracting Interleukin-15 to Elucidate Its Modes of Action in Physiology and Pathology

Erwan Mortier , Mike Maillasson , Agnès Quéméner
Journal of Interferon and Cytokine Research, 2023, 43 (1), pp.2 - 22. ⟨10.1089/jir.2022.0198⟩
Journal articles inserm-03948405v1
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Rational modification, synthesis and biological evaluation of N-substituted phthalazinone derivatives designed to target interleukine-15 protein

Jimmy Smadja , Agnès Quéméner , Mike Maillasson , Benoit Sicard , Aurélien Leray , et al.
Bioorganic & Medicinal Chemistry Letters, 2021, 39, pp.116161. ⟨10.1016/j.bmc.2021.116161⟩
Journal articles inserm-03214947v3

Reversible DNA Hypermethylation of the Interleukin-15 (IL-15) Promoter Induces IL-15 Expression, Drives the Pathogenesis of T-Cell Large Granular Lymphocytic Leukemia and Provides a Potential Therapeutic Approach Using 5-Azacitidine

Jonathan Brammer , Amy Boles , Anthony Mansour , Aharon Freud , Monique Mathé-Allainmat , et al.
61th ASH Annual Meeting, Dec 2019, Orlando, Florida, United States. pp.3776-3776, ⟨10.1182/blood-2019-131174⟩
Conference papers inserm-02991752v1
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The Exon-3-Encoded Domain of IL-15Rα Contributes to IL-15 High-Affinity Binding and Is Crucial for the IL-15 Antagonistic Effect of Soluble IL-15Rα

Grégory Bouchaud , Laure Garrigue-Antar , Véronique Solé , Agnès Quéméner , Yvan Boublik , et al.
Journal of Molecular Biology, 2008, 382 (1), pp.1 - 12. ⟨10.1016/j.jmb.2008.07.019⟩
Journal articles istex inserm-02533457v1
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High antitumor activity of RLI, an interleukin-15 (IL-15)-IL-15 receptor α fusion protein, in metastatic melanoma and colorectal cancer

Anne Bessard , Véronique Solé , Grégory Bouchaud , Agnès Quéméner , Yannick Jacques
Molecular Cancer Therapeutics, 2009, 8 (9), pp.2736-2745. ⟨10.1158/1535-7163.MCT-09-0275⟩
Journal articles inserm-02440759v1

Highly potent anti-CD20-RLI immunocytokine targeting established human B lymphoma in SCID mouse

Marie Vincent , Géraldine Teppaz , Laurie Lajoie , Véronique Solé , Anne Bessard , et al.
mAbs, 2014, 6 (4), pp.1026 - 1037. ⟨10.4161/mabs.28699⟩
Journal articles hal-01680794v1
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Selective Targeting of IL-15Rα Is Sufficient to Reduce Inflammation

Dihia Meghnem , Mike Maillasson , Isabelle Barbieux , Sébastien Morisseau , Dalloba Keita , et al.
Frontiers in Immunology, 2022, 13, pp.886213. ⟨10.3389/fimmu.2022.886213⟩
Journal articles inserm-03672135v1
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Cutting Edge: Differential Fine-Tuning of IL-2- and IL-15- Dependent Functions by targeting their Common IL-2/15Rβ/γc Receptor

Dihia Meghnem , Sébastien Morisseau , Marie Frutoso , Kilian Trillet , Mike Maillasson , et al.
Journal of Immunology, 2017, 198 (12), pp.4563-4568. ⟨10.4049/jimmunol.1700046⟩
Journal articles inserm-01524397v1
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Two novel variants of uncertain significance in GP9 associated with Bernard–Soulier syndrome: Are they true mutations?

Pierre Boisseau , Camille Debord , Marion Eveillard , Agnès Quéméner , Marianne Sigaud , et al.
Platelets, 2017, 29 (3), pp.316 - 318. ⟨10.1080/09537104.2017.1371288⟩
Journal articles inserm-01807674v1
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Molecular evolution and antigenic variation of European brown hare syndrome virus (EBHSV)

Ana M. Lopes , Lorenzo Capucci , Dolores Gavier-Widén , Ghislaine Le Gall-Reculé , Emiliana Brocchi , et al.
Virology, 2014, 468-470, pp.104-112. ⟨10.1016/j.virol.2014.08.002⟩
Journal articles inserm-02441033v1
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Mechanistic and Structural Insights on the IL-15 System through Molecular Dynamics Simulations

Rui P Sousa , Adèle Laurent , Agnès Quéméner , Erwan Mortier , Jean-Yves Le Questel
Molecules, 2019, 24 (18), pp.3261. ⟨10.3390/molecules24183261⟩
Journal articles inserm-02289307v1
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Antitumor activity of an immunocytokine composed of an anti-GD2 antibody and the IL-15 superagonist RLI

Marie Vincent , Agnès Quéméner , Yannick Jacques
OncoImmunology, 2013, ⟨10.4161/onci.26441⟩
Journal articles inserm-02440743v1
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Docking of Human Interleukin-15 to its Specific Receptor α Chain: Correlation Between Molecular Modeling and Mutagenesis Experimental Data

Agnès Quéméner , Jérôme Bernard , Erwan Mortier , Ariane Plet , Yannick Jacques , et al.
Proteins - Structure, Function and Bioinformatics, 2006, 65 (3), pp.623
Journal articles inserm-02442432v1


Carole Guillonneau , Ignacio Anegon , Erwan Mortier , Agnès Quéméner
France, Patent n° : WO2020148338. 2020
Patents inserm-02991886v1
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Emergence of NK Cell Hyporesponsiveness after Two IL-15 Stimulation Cycles

Marie Frutoso , Sébastien Morisseau , Fella Tamzalit , Agnès Quéméner , Dihia Meghnem , et al.
Journal of Immunology, 2018, Epub ahead of print. ⟨10.4049/jimmunol.1800086⟩
Journal articles inserm-01805185v1
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Centromeric KIR AA Individuals Harbor Particular KIR Alleles Conferring Beneficial NK Cell Features with Implications in Haplo-Identical Hematopoietic Stem Cell Transplantation

Léa Dubreuil , Bercelin Maniangou , Patrice Chevallier , Agnès Quéméner , Nolwenn Legrand , et al.
Cancers, 2020, 12 (12), pp.3595. ⟨10.3390/cancers12123595⟩
Journal articles inserm-03035170v1
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Genetic diversity and evolution of Hare Calicivirus (HaCV), a recentlyidentified lagovirus fromLepus europaeus

Clément Droillard , Evelyne Lemaitre , Marina Chatel , Agnès Quéméner , François-Xavier Briand , et al.
Infection, Genetics and Evolution, 2020, pp.104310. ⟨10.1016/j.meegid.2020.104310⟩
Journal articles inserm-02533007v1