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                    <forename type="first">Francesc</forename>
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                    <forename type="first">Michael</forename>
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              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">133274</idno>
                <idno type="issn">2589-5370</idno>
                <title level="j">EClinicalMedicine</title>
                <imprint>
                  <publisher>Elsevier</publisher>
                  <biblScope unit="volume">65</biblScope>
                  <biblScope unit="pp">102307</biblScope>
                  <date type="datePub">2023-11</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1016/j.eclinm.2023.102307</idno>
              <idno type="pubmed">38033506</idno>
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              <language ident="en">English</language>
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            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">Chronic lymphocytic leukemia</term>
                <term xml:lang="en">Other cancers</term>
                <term xml:lang="en">Other malignancies</term>
                <term xml:lang="en">Second primary malignancies</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv.spee">Life Sciences [q-bio]/Santé publique et épidémiologie</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
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            <abstract xml:lang="en">
              <p>Background: Patients with chronic lymphocytic leukemia (CLL) have a higher risk of developing other malignancies (OMs) compared to the general population. However, the impact of CLL-related risk factors and CLL-directed treatment is still unclear and represents the focus of this work.Methods: We conducted a retrospective international multicenter study to assess the incidence of OMs and detect potential risk factors in 19,705 patients with CLL, small lymphocytic lymphoma, or high-count CLL-like monoclonal B-cell lymphocytosis, diagnosed between 2000 and 2016. Data collection took place between October 2020 and March 2022.Findings: In 129,254 years of follow-up after CLL diagnosis, 3513 OMs were diagnosed (27.2 OMs/1000 person-years). The most common hematological OMs were Richter transformation, myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Non-melanoma skin (NMSC) and prostate cancers were the most common solid tumors (STs).The only predictor for MDS and AML development was treatment with fludarabine and cyclophosphamide with/without rituximab (FC ± R) (OR = 3.7; 95% CI = 2.79-4.91; p &amp;lt; 0.001). STs were more frequent in males and patients with unmutated immunoglobulin heavy variable genes (OR = 1.77; 95% CI = 1.49-2.11; p &amp;lt; 0.001/OR = 1.89; 95% CI = 1.6-2.24; p &amp;lt; 0.001).CLL-directed treatment was associated with non-melanoma skin and prostate cancers (OR = 1.8; 95% CI = 1.36-2.41; p &amp;lt; 0.001/OR = 2.11; 95% CI = 1.12-3.97; p = 0.021). In contrast, breast cancers were more frequent in untreated patients (OR = 0.17; 95% CI = 0.08-0.33; p &amp;lt; 0.001).Patients with CLL and an OM had inferior overall survival (OS) than those without. AML and MDS conferred the worst OS (p &amp;lt; 0.001).Interpretation: OMs in CLL impact on OS. Treatment for CLL increased the risk for AML/MDS, prostate cancer, and NMSC. FCR was associated with increased risk for AML/MDS.</p>
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          <orgName type="acronym">CERTH</orgName>
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            <address>
              <addrLine>6th Klm. Charilaou - Thermi Road P.O. BOX 60361 GR - 570 01 Thermi, Thessaloniki GREECE</addrLine>
              <country key="GR"/>
            </address>
            <ref type="url">http://www.certh.gr/root.en.aspx</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-333755" status="VALID">
          <orgName>Universita Vita Salute San Raffaele = Vita-Salute San Raffaele University [Milan, Italie]</orgName>
          <orgName type="acronym">UniSR</orgName>
          <desc>
            <address>
              <addrLine>Via Olgettina Milano, 58, 20132 Milano, Italie</addrLine>
              <country key="IT"/>
            </address>
            <ref type="url">http://www.unisr.it/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1076508" status="INCOMING">
          <orgName>Institute of Applied Biosciences [Thessaloniki, Greece]</orgName>
          <orgName type="acronym">INAB</orgName>
          <desc>
            <address>
              <addrLine>6th km Charilaou-ThermiRoad P.O. BOX 60361 GRThessaloniki, Greece</addrLine>
              <country key="GR"/>
            </address>
            <ref type="url">https://www.inab.certh.gr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-329376" status="VALID">
          <idno type="ROR">https://ror.org/01qg3j183</idno>
          <orgName>University of Ioannina</orgName>
          <desc>
            <address>
              <addrLine>45110 Ioannina</addrLine>
              <country key="GR"/>
            </address>
            <ref type="url">http://www.uoi.gr/en/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-447453" status="INCOMING">
          <orgName>Institute of Applied Biosciences, Centre for Research and Technology-Hellas, Thessaloniki, Greece;</orgName>
          <desc>
            <address>
              <country key="GR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-410219" status="VALID">
          <orgName>Vall d'Hebron University Hospital [Barcelona]</orgName>
          <desc>
            <address>
              <addrLine>C/ Natzaret, 115-11708035 Barcelona</addrLine>
              <country key="ES"/>
            </address>
            <ref type="url">http://www.vhio.net/about-vhio/en_hospital-vall-hebron.php</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-333321" status="VALID">
          <idno type="ROR">https://ror.org/00qq1fp34</idno>
          <orgName>University Hospital Brno</orgName>
          <date type="start">1998-01-01</date>
          <desc>
            <address>
              <addrLine>Jihlavská 20, CZ - 625 00 Brno</addrLine>
              <country key="CZ"/>
            </address>
            <ref type="url">https://www.fnbrno.cz/en/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-412450" status="VALID">
          <idno type="IdRef">030138566</idno>
          <idno type="ISNI">0000000121940956</idno>
          <idno type="ROR">https://ror.org/02j46qs45</idno>
          <idno type="Wikidata">Q763586</idno>
          <orgName>Masaryk University [Brno] = Masarykova univerzita [Brno] = Université Masaryk [Brno]</orgName>
          <orgName type="acronym">MU / MUNI</orgName>
          <date type="start">1919-01-28</date>
          <desc>
            <address>
              <addrLine>Žerotínovo nám. 617/9 – 601 77 Brno – Czech Republic</addrLine>
              <country key="CZ"/>
            </address>
            <ref type="url">https://www.muni.cz/en</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-533376" status="INCOMING">
          <orgName>Hematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece</orgName>
          <desc>
            <address>
              <country key="GR"/>
            </address>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-189693" status="VALID">
          <orgName>Faculty of Medicine in Hradec Kralove [Republique Tchèque]</orgName>
          <desc>
            <address>
              <addrLine>Charles UniversityFaculty of Medicinein Hradec Kralove  - Simkova 870 Hradec Kralove, 500 03 Czech Republic</addrLine>
              <country key="CZ"/>
            </address>
            <ref type="url">https://www.lfhk.cuni.cz/default.aspx/?lang=en-gb</ref>
          </desc>
          <listRelation>
            <relation active="#struct-304738" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-349561" status="VALID">
          <orgName>Royal North Shore Hospital</orgName>
          <orgName type="acronym">RNSH</orgName>
          <date type="start">2016-08-02</date>
          <desc>
            <address>
              <country key="AU"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300499" status="VALID">
          <idno type="IdRef">026430053</idno>
          <idno type="ISNI">000000012187758X</idno>
          <idno type="ROR">https://ror.org/02f40zc51</idno>
          <orgName>Universidad de Salamanca [España] = University of Salamanca [Spain]</orgName>
          <date type="start">1218-01-01</date>
          <desc>
            <address>
              <addrLine>Patio de Escuelas 1, 37008 Salamanca. España</addrLine>
              <country key="ES"/>
            </address>
            <ref type="url">https://www.usal.es/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300750" status="VALID">
          <orgName>Kuwait University</orgName>
          <desc>
            <address>
              <country key="KW"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-301325" status="VALID">
          <idno type="ROR">https://ror.org/04s3t1g37</idno>
          <orgName>Institut Paoli-Calmettes</orgName>
          <orgName type="acronym">IPC</orgName>
          <desc>
            <address>
              <addrLine>232 Boulevard de Sainte-Marguerite13009 Marseille</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.institutpaolicalmettes.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-301051" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-338859" status="VALID">
          <orgName>University Hospital of Siena</orgName>
          <desc>
            <address>
              <addrLine>53100 Siena, Province of Siena</addrLine>
              <country key="IT"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-131861" status="VALID">
          <idno type="ISNI">0000 0004 0407 1981</idno>
          <idno type="ROR">https://ror.org/012p63287</idno>
          <idno type="Wikidata">Q850730</idno>
          <orgName>University of Groningen [Groningen]</orgName>
          <date type="start">1614-01-01</date>
          <desc>
            <address>
              <addrLine>PO Box 72 , 9700 AB Groningen</addrLine>
              <country key="NL"/>
            </address>
            <ref type="url">http://www.rug.nl/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-28493" status="VALID">
          <idno type="ROR">https://ror.org/02yw1f353</idno>
          <orgName>Institut Bergonié [Bordeaux]</orgName>
          <desc>
            <address>
              <addrLine>229, cours de l'Argonne - 33076 Bordeaux</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.bergonie.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-502406" type="direct"/>
          </listRelation>
        </org>
        <org type="regrouplaboratory" xml:id="struct-1053152" status="VALID">
          <orgName>Université Côte d'Azur - Faculté de Médecine</orgName>
          <orgName type="acronym">UCA Faculté Médecine</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>28, Avenue de Valombrose - 06107 Nice Cedex 2</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://unice.fr/faculte-de-medecine/etudes/medecine</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1039632" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300113" status="VALID">
          <idno type="ROR">https://ror.org/05qsjq305</idno>
          <orgName>Centre Hospitalier Universitaire de Nice</orgName>
          <orgName type="acronym">CHU Nice</orgName>
          <desc>
            <address>
              <addrLine>30, Voie RomaineCS 51069 - 06001 Nice Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-nice.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1182803" status="INCOMING">
          <orgName>Hospital Costa del Sol</orgName>
          <desc>
            <address>
              <country key="ES"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1589856" status="INCOMING">
          <orgName>National Institute of Blood Disease &amp; Bone Marrow Transplantation Karachi, Pakistan. 7Faculty of Pharmacy, Ziauddin University Clifton Karachi, Pakistan.</orgName>
          <desc>
            <address>
              <country key="PK"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-572445" status="VALID">
          <orgName>IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico [Milano, Italia]</orgName>
          <desc>
            <address>
              <addrLine>Via Francesco Sforza, 35, 20122 Milano MI, Italie</addrLine>
              <country key="IT"/>
            </address>
            <ref type="url">https://www.policlinico.mi.it/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-331826" status="VALID">
          <orgName>AHEPA University General Hospital [Thessaloniki]</orgName>
          <desc>
            <address>
              <addrLine>Kiriakidi 1, Thessaloniki 546 21, Grèce</addrLine>
              <country key="GR"/>
            </address>
            <ref type="url">https://www.ahepahosp.gr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-332281" status="INCOMING">
          <orgName>Consorcio Hospital General Universitario de Valencia</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1151392" status="INCOMING">
          <orgName>University Hospitals Dorset NHS Foundation Trust [Bournemouth, UK]</orgName>
          <orgName type="acronym">UHD</orgName>
          <desc>
            <address>
              <country key="GB"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-307791" status="VALID">
          <orgName>University of Athens Medical School [Athens]</orgName>
          <desc>
            <address>
              <addrLine>Athens 115 27</addrLine>
              <country key="GR"/>
            </address>
            <ref type="url">http://school.med.uoa.gr/en/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-333925" status="VALID">
          <idno type="ROR">https://ror.org/02405mj67</idno>
          <orgName>Belfast City Hospital</orgName>
          <desc>
            <address>
              <addrLine>Lisburn Rd, Belfast BT9 7AB, Royaume-Uni</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://belfasttrust.hscni.net/hospitals/bch/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-519807" status="INCOMING">
          <orgName>Hospital de Clínicas [Montevideo]</orgName>
          <desc>
            <address>
              <country key="UY"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-471945" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-1102577" status="INCOMING">
          <orgName>University Hospital Center, Zagreb, Croatia</orgName>
        </org>
        <org type="institution" xml:id="struct-452971" status="VALID">
          <orgName>Mansoura University [Egypt]</orgName>
          <date type="start">1973-01-01</date>
          <desc>
            <address>
              <addrLine>60 El Gomhouria St, Mit Khamis WA Kafr Al Mougi, El Mansoura, Dakahlia Governorate 7650030</addrLine>
              <country key="EG"/>
            </address>
            <ref type="url">http://www.mans.edu.eg/en</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1196512" status="VALID">
          <orgName>Hospital Italiano de Buenos Aires</orgName>
          <desc>
            <address>
              <country key="AR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-331195" status="VALID">
          <orgName>Università cattolica del Sacro Cuore = Catholic University of the Sacred Heart [Roma]</orgName>
          <orgName type="acronym">Unicatt</orgName>
          <date type="start">1961-01-01</date>
          <desc>
            <address>
              <addrLine>Largo Francesco Vito, 1, 00168 Roma</addrLine>
              <country key="IT"/>
            </address>
            <ref type="url">https://roma.unicatt.it</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-543380" status="VALID">
          <orgName>Fondazione Policlinico Universitario Agostino Gemelli IRCCS</orgName>
          <date type="start">1964-07-10</date>
          <desc>
            <address>
              <addrLine>Largo Agostino Gemelli, 8, 00168 Roma</addrLine>
              <country key="IT"/>
            </address>
            <ref type="url">http://www.policlinicogemelli.it/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-165436" status="INCOMING">
          <orgName>Department of Oncology, Transplants and Advanced Technologies, Section of Hematology</orgName>
          <desc>
            <address>
              <addrLine>Via Roma 67;56100;Pisa</addrLine>
              <country key="IT"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-366408" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-327075" status="VALID">
          <orgName>ARNAS “Garibaldi, S. Luigi-Currò, Ascoli-Tomaselli”</orgName>
          <desc>
            <address>
              <country key="IT"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-329556" status="INCOMING">
          <orgName>Hospital General Universitario de Valencia</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-116622" status="VALID">
          <orgName>IMIM-Hospital del Mar</orgName>
          <desc>
            <address>
              <addrLine>Parc de Recerca Biomèdica de Barcelona C/ Doctor Aiguader, 88 08003 Barcelona</addrLine>
              <country key="ES"/>
            </address>
            <ref type="url">http://www.imim.es/en_index.html</ref>
          </desc>
          <listRelation>
            <relation active="#struct-308760" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-525391" status="VALID">
          <idno type="ROR">https://ror.org/05nfzf209</idno>
          <idno type="Wikidata">Q30280177</idno>
          <orgName>Hospital Universitario Infanta Leonor [Madrid]</orgName>
          <desc>
            <address>
              <addrLine>Gran Vía del Este, 80, 28031 Madrid</addrLine>
              <country key="ES"/>
            </address>
            <ref type="url">https://www.comunidad.madrid/hospital/infantaleonor/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-348505" status="VALID">
          <orgName>Azienda Ospedaliera Universitaria Senese</orgName>
          <desc>
            <address>
              <country key="IT"/>
            </address>
            <ref type="url">http://www.ao-siena.toscana.it/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-302646" status="VALID">
          <idno type="ISNI">0000000417573630</idno>
          <idno type="ROR">https://ror.org/00x27da85</idno>
          <orgName>Università degli Studi di Perugia = University of Perugia</orgName>
          <orgName type="acronym">UNIPG</orgName>
          <date type="start">1308-01-01</date>
          <desc>
            <address>
              <addrLine>piazza Università, 1, 06123 Perugia</addrLine>
              <country key="IT"/>
            </address>
            <ref type="url">https://www.unipg.it/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-341508" status="VALID">
          <orgName>Ospedale "Santa Maria della Misericordia" = University Hospital "Santa Maria della Misericordia"</orgName>
          <desc>
            <address>
              <addrLine>Via Pozzuolo n° 33033100 UDINE (UD)</addrLine>
              <country key="IT"/>
            </address>
            <ref type="url">https://asufc.sanita.fvg.it/it/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-300144" status="VALID">
          <idno type="IdRef">026606836</idno>
          <idno type="ISNI">0000000406394151</idno>
          <idno type="ROR">https://ror.org/02tcf7a68</idno>
          <orgName>CHU Clermont-Ferrand</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-clermontferrand.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-1063706" status="VALID">
          <idno type="IdRef">252544293</idno>
          <idno type="RNSR">201722572R</idno>
          <orgName>Role of intra-Clonal Heterogeneity and Leukemic environment in ThErapy Resistance of chronic leukemias</orgName>
          <orgName type="acronym">CHELTER</orgName>
          <date type="start">2021-01-01</date>
          <desc>
            <address>
              <addrLine>CHU Estaing, 1 Place Lucie et Raymond Aubrac, Hématologie Biologique, 63003 Clermont-Ferrand Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://chelter.uca.fr/</ref>
          </desc>
          <listRelation>
            <relation name="EA7453" active="#struct-1063463" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-557182" status="VALID">
          <idno type="ROR">https://ror.org/02dwcqs71</idno>
          <orgName>All India Institute of Medical Sciences [New Delhi]</orgName>
          <desc>
            <address>
              <addrLine>Ansari Nagar, New Delhi - 110029</addrLine>
              <country key="IN"/>
            </address>
            <ref type="url">https://www.aiims.edu/en.html</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-306322" status="VALID">
          <idno type="ROR">https://ror.org/01ej9dk98</idno>
          <orgName>University of Melbourne</orgName>
          <desc>
            <address>
              <addrLine>Parkville VIC 3010</addrLine>
              <country key="AU"/>
            </address>
            <ref type="url">http://www.unimelb.edu.au/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-335491" status="VALID">
          <idno type="ROR">https://ror.org/04nd58p63</idno>
          <orgName>Tel Aviv Sourasky Medical Center [Tel Aviv]</orgName>
          <desc>
            <address>
              <addrLine>Weizmann St 6, Tel Aviv-Yafo</addrLine>
              <country key="IL"/>
            </address>
            <ref type="url">http://www.tasmc.org.il/sites/en/Pages/default.aspx</ref>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-550671" status="INCOMING">
          <orgName>Zagreb School of Medicine [Zagreb, Croatia]</orgName>
          <orgName type="acronym">Dubrava University Hospital</orgName>
          <desc>
            <address>
              <country key="HR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-28059" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-1101678" status="VALID">
          <idno type="ROR">https://ror.org/05grdyy37</idno>
          <orgName>Amsterdam University Medical Centers</orgName>
          <orgName type="acronym">Amsterdam UMC</orgName>
          <desc>
            <address>
              <addrLine>1105 AZ Amsterdam</addrLine>
              <country key="NL"/>
            </address>
            <ref type="url">https://www.amsterdamumc.org/en/about/organization/about-amsterdam-umc.htm</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-120654" status="VALID">
          <idno type="IdRef">026431610</idno>
          <idno type="ISNI">0000 0000 8499 2262</idno>
          <idno type="ROR">https://ror.org/04dkp9463</idno>
          <idno type="Wikidata">Q214341</idno>
          <orgName>Universiteit van Amsterdam = University of Amsterdam</orgName>
          <orgName type="acronym">UvA</orgName>
          <date type="start">1632-01-01</date>
          <desc>
            <address>
              <addrLine>Spui 21 1012 WX Amsterdam</addrLine>
              <country key="NL"/>
            </address>
            <ref type="url">https://www.uva.nl/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-333548" status="VALID">
          <idno type="ROR">https://ror.org/01qpw1b93</idno>
          <orgName>Wrocław Medical University</orgName>
          <desc>
            <address>
              <addrLine>Wroclaw Medical UniversityWybrzeże L. Pasteura 1, 50-367 Wrocław</addrLine>
              <country key="PL"/>
            </address>
            <ref type="url">https://en.umw.edu.pl/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-529829" status="VALID">
          <idno type="ROR">https://ror.org/03bf2nz41</idno>
          <orgName>Centre Hospitalier Le Mans (CH Le Mans)</orgName>
          <desc>
            <address>
              <addrLine>Centre Hospitalier Le Mans194 av. Rubillard 72037 LE MANS CEDEX 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ch-lemans.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-498156" status="INCOMING">
          <orgName>Medical Park Antalya Hospital [Turkey]</orgName>
          <desc>
            <address>
              <addrLine>Fener Mahallesi, Tekelioğlu Cd. No:7, 07160 Muratpaşa/Antalya</addrLine>
              <country key="TR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-339691" status="INCOMING">
          <orgName>Pamela Youde Nethersole Eastern Hospital</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1087098" status="INCOMING">
          <orgName>City Clinical Hospital Named After S.P. Botkin [Moscow, Russian Federation]</orgName>
          <orgName type="acronym">2CHNSPB</orgName>
          <desc>
            <address>
              <country key="RU"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-323441" status="INCOMING">
          <orgName>Laikon General Hospital</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1235369" status="INCOMING">
          <orgName>Shamir Medical Center</orgName>
          <desc>
            <address>
              <country key="IL"/>
            </address>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-63133" status="VALID">
          <idno type="ROR">https://ror.org/04mhzgx49</idno>
          <orgName>Tel Aviv University</orgName>
          <orgName type="acronym">TAU</orgName>
          <desc>
            <address>
              <addrLine>Tel Aviv 699780</addrLine>
              <country key="IL"/>
            </address>
            <ref type="url">https://english.tau.ac.il/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1142810" status="INCOMING">
          <orgName>Alexandroupolis University Hospital [Alexandroupolis, Greece]</orgName>
          <orgName type="acronym">AUH</orgName>
          <desc>
            <address>
              <country key="GR"/>
            </address>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-71832" status="INCOMING">
          <orgName>University of Thrace</orgName>
          <desc>
            <address>
              <country key="GR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-494787" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-305678" status="VALID">
          <idno type="ROR">https://ror.org/040gcmg81</idno>
          <orgName>National Cancer Institute [Bethesda]</orgName>
          <orgName type="acronym">NCI-NIH</orgName>
          <date type="start">1937-01-01</date>
          <desc>
            <address>
              <addrLine>BG 9609 MSC 9760, 9609 Medical Center Drive, Bethesda, MD 20892-9760</addrLine>
              <country key="US"/>
            </address>
            <ref type="url">https://www.cancer.gov/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1182789" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-303869" status="VALID">
          <idno type="ROR">https://ror.org/049da5t36</idno>
          <orgName>Universidad de Burgos = University of Burgos</orgName>
          <desc>
            <address>
              <addrLine>09001 Burgos</addrLine>
              <country key="ES"/>
            </address>
            <ref type="url">http://www.ubu.es/departamento-de-fisica</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1193116" status="VALID">
          <orgName>Postgraduate Institute of Medical Education &amp; Research</orgName>
          <orgName type="acronym">PGIMER</orgName>
          <desc>
            <address>
              <addrLine>Postgraduate Institute of Medical Education &amp; ResearchSector-12, Chandigarh PIN- 160012, INDIA</addrLine>
              <country key="IN"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-335242" status="INCOMING">
          <orgName>Albert Schweitzer Hospital</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-169367" status="VALID">
          <orgName>UNIROUEN - UFR Santé</orgName>
          <orgName type="acronym">UNIROUEN UFR Santé</orgName>
          <desc>
            <address>
              <addrLine>22 boulevard Gambetta - CS 76183 - 76183 Rouen cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://medecine-pharmacie.univ-rouen.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300318" type="direct"/>
            <relation active="#struct-455934" type="indirect"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-302301" status="VALID">
          <orgName>Centre Hospitalier de Versailles André Mignot</orgName>
          <orgName type="acronym">CHV</orgName>
          <desc>
            <address>
              <addrLine>Versailles, Trappes, Andrésy et Bois d'Arcy, Chesnay</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.ch-versailles.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-463036" status="VALID">
          <idno type="ISNI">0000 0000 9538 1950</idno>
          <idno type="ROR">https://ror.org/049nvyb15</idno>
          <idno type="Wikidata">Q10946560</idno>
          <orgName>Hospital Universitario Fundación Jiménez Díaz [Madrid]</orgName>
          <orgName type="acronym">FJD</orgName>
          <date type="start">1970-01-01</date>
          <desc>
            <address>
              <addrLine>Avda. Reyes Católicos, 2, 28040 Madrid</addrLine>
              <country key="ES"/>
            </address>
            <ref type="url">https://www.fjd.es/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1582281" status="INCOMING">
          <orgName>Ramón y Cajal University Hospital</orgName>
          <desc>
            <address>
              <country key="ES"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-98227" status="VALID">
          <idno type="ISNI">0000 0001 2296 0625</idno>
          <idno type="ROR">https://ror.org/052g8jq94</idno>
          <orgName>Universitat Autònoma de Barcelona = Autonomous University of Barcelona = Universidad Autónoma de Barcelona</orgName>
          <orgName type="acronym">UAB</orgName>
          <date type="start">1968-01-01</date>
          <desc>
            <address>
              <addrLine>UAB Campus 08193 Bellaterra Barcelona</addrLine>
              <country key="ES"/>
            </address>
            <ref type="url">https://www.uab.cat/</ref>
          </desc>
        </org>
        <org type="researchteam" xml:id="struct-1229450" status="VALID">
          <orgName>Épigénétique, épidémiologie et thérapies personnalisées des hémopathies malignes : EPI2THM (CTM UMR 1231)</orgName>
          <orgName type="acronym">EPI2THM</orgName>
          <date type="start">2025-01-01</date>
          <desc>
            <address>
              <addrLine>7 Bd Jeanne d’Arc21000 Dijon CEDEX</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://ctm.ube.fr/index.php/02-menu/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1229443" type="direct"/>
            <relation name="UMR 1231" active="#struct-110691" type="indirect"/>
            <relation active="#struct-564132" type="indirect"/>
            <relation name="UMR 1231" active="#struct-303623" type="indirect"/>
            <relation name="UMR 1231" active="#struct-1096329" type="indirect"/>
            <relation active="#struct-1042499" type="indirect"/>
            <relation name="UMR 1231" active="#struct-1220685" type="indirect"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300924" status="VALID">
          <idno type="ROR">https://ror.org/0377z4z10</idno>
          <orgName>Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand</orgName>
          <orgName type="acronym">CHU Dijon</orgName>
          <desc>
            <address>
              <addrLine>14 rue Paul Gaffarel - 21079 Dijon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-dijon.fr/fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-157323" status="VALID">
          <idno type="ROR">https://ror.org/03cg5md32</idno>
          <orgName>Hospital Universitario de La Princesa</orgName>
          <desc>
            <address>
              <addrLine>C/ Diego de León, 62. 28006 Madrid</addrLine>
              <country key="ES"/>
            </address>
            <ref type="url">https://www.comunidad.madrid/hospital/laprincesa/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1148387" status="VALID">
          <orgName>University Clinical Centre of Serbia</orgName>
          <desc>
            <address>
              <country key="RS"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-167343" status="VALID">
          <idno type="ROR">https://ror.org/02qsmb048</idno>
          <orgName>University of Belgrade [Belgrade]</orgName>
          <desc>
            <address>
              <addrLine>Studentski Trg 1, 11000 Belgrade</addrLine>
              <country key="RS"/>
            </address>
            <ref type="url">http://www.bg.ac.rs/en_index.php</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-309583" status="VALID">
          <idno type="IdRef">029717523</idno>
          <idno type="ROR">https://ror.org/00xa57a59</idno>
          <orgName>University of Novi Sad</orgName>
          <desc>
            <address>
              <addrLine>Novi Sad 402920, Serbia</addrLine>
              <country key="RS"/>
            </address>
            <ref type="url">http://www.uns.ac.rs/en/o_univerzitetu.htm</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-314146" status="VALID">
          <idno type="ROR">https://ror.org/00qyh5r35</idno>
          <orgName>Hospital Universitario 12 de Octubre = University Hospital October 12 [Madrid]</orgName>
          <desc>
            <address>
              <addrLine>Avda. de Córdoba, s/n 28041 Madrid</addrLine>
              <country key="ES"/>
            </address>
            <ref type="url">https://www.comunidad.madrid/hospital/12octubre/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-226973" status="VALID">
          <idno type="IdRef">081945760</idno>
          <idno type="ROR">https://ror.org/04387x656</idno>
          <orgName>Università degli Studi del Piemonte Orientale - Amedeo Avogadro</orgName>
          <orgName type="acronym">UPO</orgName>
          <date type="start">1991-01-01</date>
          <desc>
            <address>
              <addrLine>Via Duomo, 6 - 13100 Vercelli</addrLine>
              <country key="IT"/>
            </address>
            <ref type="url">https://www.uniupo.it</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-116455" status="VALID">
          <idno type="ROR">https://ror.org/04k51q396</idno>
          <orgName>University Hospital Basel [Basel]</orgName>
          <desc>
            <address>
              <addrLine>Hebelstrasse 32CH - 4031 Basel</addrLine>
              <country key="CH"/>
            </address>
            <ref type="url">http://www.swisshealth.ch/fr/patienten/spitaeler/uhbs.php</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1399791" status="INCOMING">
          <orgName>Gastroenterology Unit, ARNAS G. Brotzu, Cagliari, Italy.</orgName>
          <desc>
            <address>
              <country key="IT"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-573302" status="VALID">
          <idno type="ROR">https://ror.org/04hya7017</idno>
          <orgName>Centro de Investigación Biomédica en Red de Cáncer</orgName>
          <orgName type="acronym">CIBERONC</orgName>
          <desc>
            <address>
              <addrLine>Av. Monforte de Lemos, 3-5. Pabellón 11. Planta 0 28029 Madrid</addrLine>
              <country key="ES"/>
            </address>
            <ref type="url">https://www.ciberonc.es</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-43892" status="INCOMING">
          <orgName>Laboratorio de Patología Molecular</orgName>
          <orgName type="acronym">USAL-CSIC</orgName>
          <desc>
            <address>
              <addrLine>37007 Salamanca</addrLine>
              <country key="ES"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-571447" type="direct"/>
            <relation active="#struct-300499" type="indirect"/>
            <relation active="#struct-501252" type="indirect"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-1496695" status="INCOMING">
          <orgName>RISE-Health</orgName>
          <desc>
            <address>
              <country key="PT"/>
            </address>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-19144" status="VALID">
          <orgName>Universidade do Porto = University of Porto</orgName>
          <date type="start">1911-01-01</date>
          <desc>
            <address>
              <addrLine>Praça de Gomes Teixeira, 4099-002 Porto</addrLine>
              <country key="PT"/>
            </address>
            <ref type="url">https://sigarra.up.pt/up/pt/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1635697" status="INCOMING">
          <orgName>General Manager of the entity Azienda Sanitaria Universitaria Friuli Centrale (ASUFC), Italy.</orgName>
          <desc>
            <address>
              <country key="IT"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-302377" status="VALID">
          <idno type="ROR">https://ror.org/02wk2vx54</idno>
          <orgName>Ss. Cyril and Methodius University in Skopje / Универзитет „Св. Кирил и Методиј“ во Скопје [Skopje, Republic of North Macedonia]</orgName>
          <orgName type="acronym">UKIM</orgName>
          <date type="start">1949-01-01</date>
          <desc>
            <address>
              <addrLine>blvd. Goce Delcev 9, 1000 Skopje</addrLine>
              <country key="MK"/>
            </address>
            <ref type="url">https://www.ukim.edu.mk/en_index.php</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-301857" status="VALID">
          <orgName>University of Cyprus = Université de Chypre</orgName>
          <date type="start">1992-01-01</date>
          <desc>
            <address>
              <addrLine>Nicosie</addrLine>
              <country key="CY"/>
            </address>
            <ref type="url">https://www.ucy.ac.cy/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-341936" status="VALID">
          <idno type="ROR">https://ror.org/04qxnmv42</idno>
          <orgName>Palacky University Olomouc</orgName>
          <date type="start">1573-01-01</date>
          <desc>
            <address>
              <addrLine>Olomouc, Moravie</addrLine>
              <country key="CZ"/>
            </address>
            <ref type="url">http://www.upol.cz/en/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-327038" status="INCOMING">
          <orgName>University Hospital Olomouc [Czech Republic]</orgName>
          <desc>
            <address>
              <addrLine>Fakultni Nemocnice Olomouc - I.P. Pavlova 185, Nová Ulice, 779 00 Olomouc, Tchéquie</addrLine>
              <country key="CZ"/>
            </address>
            <ref type="url">https://www.fnol.cz/</ref>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-1114656" status="VALID">
          <orgName>Hull York Medical School [York, UK]</orgName>
          <orgName type="acronym">HYMS</orgName>
          <desc>
            <address>
              <addrLine>Heslington, York YO10 5DD</addrLine>
              <country key="GB"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-450355" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-165486" status="INCOMING">
          <orgName>Laboratoris de Citologia Hematológica/Citogenética Molecular. Servei de Patologia, GRETNHE</orgName>
          <desc>
            <address>
              <addrLine>Barcelona</addrLine>
              <country key="ES"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-325570" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-463501" status="VALID">
          <orgName>Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico</orgName>
          <desc>
            <address>
              <addrLine>Milano</addrLine>
              <country key="IT"/>
            </address>
            <ref type="url">http://www.policlinico.mi.it/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-304516" status="VALID">
          <orgName>Università degli Studi di Ferrara = University of Ferrara</orgName>
          <orgName type="acronym">UniFE</orgName>
          <desc>
            <address>
              <addrLine>via Ludovico Ariosto, 35, 44121 Ferrara</addrLine>
              <country key="IT"/>
            </address>
            <ref type="url">http://www.unife.it</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-348236" status="VALID">
          <idno type="ISNI">0000 0004 0372 2295</idno>
          <orgName>The Hebrew University Hadassah Medical School</orgName>
          <desc>
            <address>
              <addrLine>The Hebrew University of Jerusalem, Ein Kerem.P.O. Box 12271, Jerusalem, 9112102 Israel</addrLine>
              <country key="IL"/>
            </address>
            <ref type="url">https://medicine.ekmd.huji.ac.il/En/academicUnits/medicine/Pages/default.aspx</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-338888" status="INCOMING">
          <orgName>Shaare Zedek Medical Center</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1001219" status="VALID">
          <idno type="ROR">https://ror.org/05sxf4h28</idno>
          <orgName>Universidade Federal do Espirito Santo</orgName>
          <orgName type="acronym">UFES</orgName>
          <desc>
            <address>
              <addrLine>Vitória</addrLine>
              <country key="BR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-137012" status="VALID">
          <orgName>Amedeo Avogadro University of Eastern Piedmont</orgName>
          <desc>
            <address>
              <addrLine>28100;Novara</addrLine>
              <country key="IT"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-67412" status="VALID">
          <idno type="IdRef">027363317</idno>
          <idno type="ISNI">0000000121089006</idno>
          <idno type="ROR">https://ror.org/03p14d497</idno>
          <idno type="Wikidata">Q616905</idno>
          <orgName>Universität Augsburg [Deutschland] = University of Augsburg [Germany] = Université d'Augsbourg [Allemagne]</orgName>
          <orgName type="acronym">UNIA</orgName>
          <date type="start">1970-01-01</date>
          <desc>
            <address>
              <addrLine>Universitaetsstr. 2 – 86159 Augsburg – Deutschland</addrLine>
              <country key="DE"/>
            </address>
            <ref type="url">http://www.uni-augsburg.de/en/</ref>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-561752" status="VALID">
          <idno type="Wikidata">Q10204045</idno>
          <orgName>3. lékařská fakulta, Univerzita Karlova [Praha, Česká republika] = Third Faculty of Medicine, Charles University [Prague, Czech Republic]</orgName>
          <orgName type="acronym">3. LF UK / 3rd Faculty of Medicine</orgName>
          <desc>
            <address>
              <addrLine>3. lékařská fakulta, Univerzita Karlova, Ruská 87, 100 00 Praha 10</addrLine>
              <country key="CZ"/>
            </address>
            <ref type="url">https://www.lf3.cuni.cz/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-304738" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-1150346" status="INCOMING">
          <orgName>Research Centre for Medical Genetics [Moscow, Russia]</orgName>
          <orgName type="acronym">RCMG</orgName>
          <desc>
            <address>
              <country key="RU"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-580796" status="VALID">
          <orgName>Hamad Medical Corporation [Doha, Qatar]</orgName>
          <desc>
            <address>
              <addrLine>Doha</addrLine>
              <country key="QA"/>
            </address>
            <ref type="url">https://www.hamad.qa/EN/Pages/default.aspx</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-548302" status="VALID">
          <orgName>Institute of Phonetics of Charles University</orgName>
          <desc>
            <address>
              <addrLine>Faculty of Arts, Charles University in PragueInstitute of PhoneticsNáměstí Jana Palacha 2116 38, Praha 1Czech Republic</addrLine>
              <country key="CZ"/>
            </address>
            <ref type="url">https://fonetika.ff.cuni.cz/en/institute/current-and-history/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-304738" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-356352" status="VALID">
          <orgName>General University Hospital in Prague</orgName>
          <orgName type="acronym">VFN</orgName>
          <date type="start">1953-01-01</date>
          <desc>
            <address>
              <addrLine>U Nemocnice 499/2, 128 08 Prague 2</addrLine>
              <country key="CZ"/>
            </address>
            <ref type="url">https://www.vfn.cz/en/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-565636" status="INCOMING">
          <orgName>Bnai Zion Medical Center [Israël]</orgName>
          <desc>
            <address>
              <addrLine>Haifa, Israel</addrLine>
              <country key="IL"/>
            </address>
            <ref type="url">http://www.b-zion.org.il/default_e.aspx</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-93487" status="VALID">
          <idno type="ROR">https://ror.org/02zhqgq86</idno>
          <orgName>The University of Hong Kong</orgName>
          <orgName type="acronym">HKU</orgName>
          <desc>
            <address>
              <addrLine>Pokfulam, Hong Kong</addrLine>
              <country key="HK"/>
            </address>
            <ref type="url">http://www.hku.hk/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-502478" status="VALID">
          <idno type="ROR">https://ror.org/04gnjpq42</idno>
          <orgName>National and Kapodistrian University of Athens</orgName>
          <orgName type="acronym">NKUA</orgName>
          <date type="start">1837-04-14</date>
          <desc>
            <address>
              <addrLine>Athens 157 72</addrLine>
              <country key="GR"/>
            </address>
            <ref type="url">https://en.uoa.gr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-301093" status="VALID">
          <idno type="ROR">https://ror.org/00240q980</idno>
          <orgName>Università degli Studi di Padova = University of Padua</orgName>
          <orgName type="acronym">Unipd</orgName>
          <desc>
            <address>
              <addrLine>Via 8 Febbraio 2, 35122 Padova</addrLine>
              <country key="IT"/>
            </address>
            <ref type="url">https://www.unipd.it/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-354720" status="VALID">
          <orgName>Città della Salute e della Scienza di Torino</orgName>
          <orgName type="acronym">A.O.U</orgName>
          <date type="start">2012-01-01</date>
          <desc>
            <address>
              <addrLine>Corso Bramante, 88, 10126 Torino TO</addrLine>
              <country key="IT"/>
            </address>
            <ref type="url">https://www.cittadellasalute.to.it/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-47709" status="VALID">
          <idno type="IdRef">027548325</idno>
          <idno type="ROR">https://ror.org/048tbm396</idno>
          <orgName>Università degli studi di Torino = University of Turin</orgName>
          <orgName type="acronym">UNITO</orgName>
          <date type="start">1404-01-01</date>
          <desc>
            <address>
              <addrLine>Via Verdi, 8 10124 Torino Italie</addrLine>
              <country key="IT"/>
            </address>
            <ref type="url">http://www.unito.it/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-535610" status="VALID">
          <orgName>West German Cancer Center [Essen, Germany]</orgName>
          <desc>
            <address>
              <addrLine>University Duisburg-Essen</addrLine>
              <country key="DE"/>
            </address>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-327367" status="VALID">
          <orgName>University Hospital Essen</orgName>
          <orgName type="acronym">AöR</orgName>
          <desc>
            <address>
              <addrLine>Hufelandstrasse 5545147 Food</addrLine>
              <country key="DE"/>
            </address>
            <ref type="url">https://www.uk-essen.de/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-300612" status="VALID">
          <idno type="ROR">https://ror.org/04mz5ra38</idno>
          <orgName>Universität Duisburg-Essen = University of Duisburg-Essen [Essen]</orgName>
          <date type="start">2003-01-01</date>
          <desc>
            <address>
              <addrLine>Universitätsstraße 2, 45141 Essen</addrLine>
              <country key="DE"/>
            </address>
            <ref type="url">https://www.uni-due.de/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-494787" status="VALID">
          <orgName>Democritus University of Thrace</orgName>
          <orgName type="acronym">DUTH</orgName>
          <desc>
            <address>
              <addrLine>V. Sofias 12, Prokat, Building A1 67100 Xanthi Greece</addrLine>
              <country key="GR"/>
            </address>
            <ref type="url">http://duth.gr/index.en.shtml</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-327852" status="VALID">
          <idno type="ROR">https://ror.org/016f61126</idno>
          <orgName>Medical University of Lublin</orgName>
          <desc>
            <address>
              <country key="PL"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1221614" status="INCOMING">
          <orgName>Fujian Medical University Union Hospital, Fujian Institute of Hematology, Fuzhou</orgName>
          <desc>
            <address>
              <country key="CN"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-469520" status="VALID">
          <idno type="ROR">https://ror.org/054xkpr46</idno>
          <orgName>Gazi University</orgName>
          <date type="start">1926-01-01</date>
          <desc>
            <address>
              <addrLine>Ankara Turkey</addrLine>
              <country key="TR"/>
            </address>
            <ref type="url">https://gazi.edu.tr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1074977" status="VALID">
          <orgName>Marqués de Valdecilla Research Institute - Instituto de Investigación Marqués de Valdecilla [Santander]</orgName>
          <orgName type="acronym">IDIVAL</orgName>
          <desc>
            <address>
              <addrLine>Edificio IDIVAL, Avenida Cardenal Herrera Oria s/n, 39011 Santander</addrLine>
              <country key="ES"/>
            </address>
            <ref type="url">https://www.idival.org/en</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-557788" status="VALID">
          <orgName>Centre de Recherche Forestière [Maroc]</orgName>
          <orgName type="acronym">CRF</orgName>
          <desc>
            <address>
              <addrLine>Avenue Omar Ibn Al Khattab, Rabat</addrLine>
              <country key="MA"/>
            </address>
            <ref type="url">https://nmagri.jimdo.com/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-336972" status="VALID">
          <orgName>University Hospital Ostrava</orgName>
          <desc>
            <address>
              <country key="CZ"/>
            </address>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-165320" status="INCOMING">
          <orgName>Department of Cancer Epidemiology</orgName>
          <desc>
            <address>
              <addrLine>Im Neuenheimer Feld 280;69120;Heidelberg</addrLine>
              <country key="DE"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-150185" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-414635" status="VALID">
          <orgName>Dokuz Eylül Üniversitesi = Dokuz Eylül University [Izmir]</orgName>
          <orgName type="acronym">DEÜ</orgName>
          <date type="start">1982-01-01</date>
          <desc>
            <address>
              <addrLine>Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR</addrLine>
              <country key="TR"/>
            </address>
            <ref type="url">http://www.deu.edu.tr</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-61129" status="VALID">
          <orgName>Jet Propulsion Laboratory</orgName>
          <orgName type="acronym">JPL</orgName>
          <desc>
            <address>
              <addrLine>4800 Oak Grove Drive, Pasadena, CA 91109-8099, USA</addrLine>
              <country key="US"/>
            </address>
            <ref type="url">http://www.jpl.nasa.gov/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300681" type="direct"/>
            <relation active="#struct-340667" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-58008" status="INCOMING">
          <orgName>Russian Academy of Medical Sciences</orgName>
          <desc>
            <address>
              <addrLine>Russian Academy of Medical Sciences, 109544 Moscow,</addrLine>
              <country key="RU"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-312360" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-1053799" status="VALID">
          <idno type="ISNI">0000 0004 4690 9033</idno>
          <idno type="ROR">https://ror.org/04fkbqt11</idno>
          <orgName>Spitalul Clinic Colentina = Colentina Hospital [Bucharest, Romania]</orgName>
          <desc>
            <address>
              <addrLine>Șoseaua Ștefan cel Mare 19-21, București 020125GRID grid.414585.9</addrLine>
              <country key="RO"/>
            </address>
            <ref type="url">https://www.spitalulcolentina.ro/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-350929" status="VALID">
          <orgName>General Hospital of Thessaloniki George Papanikolaou</orgName>
          <desc>
            <address>
              <addrLine>Leof. Papanikolaou, Pilea Chortiatis 570 10, Grèce</addrLine>
              <country key="GR"/>
            </address>
            <ref type="url">https://gpapanikolaou.gr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-565656" status="VALID">
          <orgName>Alfred Health</orgName>
          <desc>
            <address>
              <country key="AU"/>
            </address>
            <ref type="url">https://www.alfredhealth.org.au/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-469589" status="VALID">
          <orgName>Monash University [Melbourne]</orgName>
          <desc>
            <address>
              <addrLine>Victoria 3800, Australia</addrLine>
              <country key="AU"/>
            </address>
            <ref type="url">https://www.monash.edu/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-302344" status="VALID">
          <idno type="ROR">https://ror.org/056d84691</idno>
          <orgName>Karolinska Institutet = Karolinska Institute [Stockholm]</orgName>
          <desc>
            <address>
              <addrLine>Solnavägen 1, 171 77 SolnaStockholm</addrLine>
              <country key="SE"/>
            </address>
            <ref type="url">http://ki.se</ref>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-424805" status="VALID">
          <orgName>Central European Institute of Technology [Brno]</orgName>
          <orgName type="acronym">CEITEC MU</orgName>
          <desc>
            <address>
              <addrLine>Masaryk University,  Kamenice 753/5 625 00 Brno</addrLine>
              <country key="CZ"/>
            </address>
            <ref type="url">http://muni.ceitec.cz/en/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-160209" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-498137" status="VALID">
          <orgName>IRCCS Ospedale San Raffaele [Milan, Italy]</orgName>
          <desc>
            <address>
              <addrLine>Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele, Via Olgettina Milano, 60, 20132 Milano.</addrLine>
              <country key="IT"/>
            </address>
            <ref type="url">https://research.hsr.it/en/index.html</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-304738" status="VALID">
          <idno type="IdRef">069566992</idno>
          <idno type="ISNI">000000012160811X</idno>
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          <idno type="Wikidata">Q31519</idno>
          <orgName>Univerzita Karlova [Praha, Česká republika] = Charles University [Prague, Czech Republic] = Université Charles  [Prague, Republique tchèque]</orgName>
          <orgName type="acronym">UK</orgName>
          <date type="start">1348-01-01</date>
          <desc>
            <address>
              <addrLine>Ovocný trh 5Prague 1116 36Czech Republic</addrLine>
              <country key="CZ"/>
            </address>
            <ref type="url">http://www.cuni.cz</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-301051" status="VALID">
          <orgName>Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-502406" status="VALID">
          <orgName>UNICANCER</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75654 Paris Cedex 13</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.unicancer.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-1039632" status="VALID">
          <idno type="IdRef">241035694</idno>
          <idno type="ROR">https://ror.org/019tgvf94</idno>
          <orgName>Université Côte d'Azur</orgName>
          <orgName type="acronym">UniCA</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>Parc Valrose, 28, avenue Valrose 06108 Nice Cedex 2</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://univ-cotedazur.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-471945" status="VALID">
          <idno type="IdRef">02642990X</idno>
          <idno type="ROR">https://ror.org/030bbe882</idno>
          <orgName>Universidad de la República de Uruguay = University of the Republic of Uruguay [Montevideo]</orgName>
          <orgName type="acronym">UDELAR</orgName>
          <date type="start">1849-07-14</date>
          <desc>
            <address>
              <country key="UY"/>
            </address>
            <ref type="url">https://udelar.edu.uy/portal/</ref>
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        <org type="institution" xml:id="struct-366408" status="VALID">
          <idno type="IdRef">026619385</idno>
          <idno type="ISNI">0000000417573729</idno>
          <idno type="ROR">https://ror.org/03ad39j10</idno>
          <idno type="Wikidata">Q645663</idno>
          <orgName>University of Pisa [Italy] = Università di Pisa [Italia] = Université de Pise [Italie]</orgName>
          <orgName type="acronym">UniPi</orgName>
          <date type="start">1343-01-01</date>
          <desc>
            <address>
              <addrLine>Lungarno Pacinotti 43 – 56126 Pisa – Italia</addrLine>
              <country key="IT"/>
            </address>
            <ref type="url">https://www.unipi.it/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-308760" status="VALID">
          <idno type="IdRef">026436051</idno>
          <idno type="ROR">https://ror.org/01bg62x04</idno>
          <orgName>Generalitat de Catalunya = Generalidad de Cataluña = Government of Catalonia = Généralité de Catalogne</orgName>
          <date type="start">1359-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://web.gencat.cat/ca/inici</ref>
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          <idno type="ISNI">0000000115480420</idno>
          <idno type="ROR">https://ror.org/01a8ajp46</idno>
          <orgName>Université Clermont Auvergne</orgName>
          <orgName type="acronym">UCA</orgName>
          <date type="start">2021-01-01</date>
          <desc>
            <address>
              <addrLine>49, bd François-Mitterrand / CS 60032 / 63001 Clermont-Ferrand Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.uca.fr/</ref>
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        </org>
        <org type="institution" xml:id="struct-28059" status="VALID">
          <idno type="ROR">https://ror.org/00mv6sv71</idno>
          <orgName>University of Zagreb</orgName>
          <desc>
            <address>
              <addrLine>p.p. 407 Trg maršala Tita 14 HR-10002 ZAGREB, CROATIA Phone: (+385 1) 4564 111 Fax: (+ 385 1) 4830 602</addrLine>
              <country key="HR"/>
            </address>
            <ref type="url">http://www.unizg.hr/homepage/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-1182789" status="VALID">
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          <idno type="Wikidata">Q390551</idno>
          <orgName>National Institutes of Health [Bethesda, MD, USA]</orgName>
          <orgName type="acronym">NIH</orgName>
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            <address>
              <addrLine>9000 Rockville Pike, Bethesda, Maryland 20892, USA</addrLine>
              <country key="US"/>
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            <ref type="url">https://www.nih.gov/</ref>
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        </org>
        <org type="institution" xml:id="struct-300318" status="VALID">
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          <idno type="ISNI">0000000121083034</idno>
          <idno type="ROR">https://ror.org/03nhjew95</idno>
          <orgName>Université de Rouen Normandie</orgName>
          <orgName type="acronym">UNIROUEN</orgName>
          <date type="start">1966-01-01</date>
          <desc>
            <address>
              <addrLine>1, rue Thomas Becket 76821 Mont-Saint-Aignan Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-rouen.fr/</ref>
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          <idno type="ISNI">0000000417859671 </idno>
          <idno type="ROR">https://ror.org/01k40cz91</idno>
          <orgName>Normandie Université</orgName>
          <orgName type="acronym">NU</orgName>
          <date type="start">2015-01-01</date>
          <desc>
            <address>
              <addrLine>Esplanade de la Paix - CS 14032 - 14032 Caen Cedex 5</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.normandie-univ.fr/</ref>
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          <idno type="RNSR">200716508T</idno>
          <idno type="ROR">https://ror.org/04d70nb60</idno>
          <orgName>Center for Translational and Molecular medicine [Dijon - UMR1231]</orgName>
          <orgName type="acronym">CTM</orgName>
          <date type="start">2025-01-01</date>
          <desc>
            <address>
              <addrLine>Université Bourgogne Europe - 7 Bd Jeanne d’Arc, 21000 Dijon CEDEX</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://ctm.ube.fr</ref>
          </desc>
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          <orgName>École Pratique des Hautes Études</orgName>
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            <address>
              <addrLine>4-14 Rue Ferrus, 75014 Paris</addrLine>
              <country key="FR"/>
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            <ref type="url">http://www.ephe.fr</ref>
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          <idno type="ISNI">0000 0004 1784 3645</idno>
          <idno type="ROR">https://ror.org/013cjyk83</idno>
          <orgName>Université Paris Sciences et Lettres</orgName>
          <orgName type="acronym">PSL</orgName>
          <desc>
            <address>
              <addrLine>60 rue Mazarine 75006 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.psl.eu/</ref>
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        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
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            <ref type="url">http://www.inserm.fr</ref>
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        <org type="institution" xml:id="struct-1096329" status="VALID">
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          <idno type="ROR">https://ror.org/03zek0r74</idno>
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          <orgName>Institut Agro Dijon</orgName>
          <date type="start">2022-01-01</date>
          <desc>
            <address>
              <addrLine>26 Boulevard du Dr Petitjean - BP 87999 - 21079 Dijon cedex</addrLine>
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          <orgName>Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement</orgName>
          <orgName type="acronym">Institut Agro</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
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            <ref type="url">https://www.institut-agro.fr</ref>
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          <idno type="IdRef">28258160X</idno>
          <idno type="ROR">https://ror.org/00g700j37</idno>
          <orgName>Université Bourgogne Europe</orgName>
          <orgName type="acronym">UBE</orgName>
          <date type="start">2025-01-01</date>
          <desc>
            <address>
              <addrLine>Maison de l'université -Esplanade Erasme -BP 27877 - 21078 DIJON Cedex France</addrLine>
              <country key="FR"/>
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            <ref type="url">https://www.ube.fr</ref>
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        <org type="regrouplaboratory" xml:id="struct-571447" status="VALID">
          <orgName>Centro de Investigación del Cáncer - Instituto Universitario De Biologia Molecular Y Celular Del Cancer (USAL-CSIC) [Salamanca, Spain]</orgName>
          <orgName type="acronym">CIC-IBMCC</orgName>
          <date type="start">1996-03-01</date>
          <desc>
            <address>
              <addrLine>Paseo Universidad De Coímbra, 0 S-N Campus Universitario Miguel De Unamuno, 37001 Salamanca, Espagne</addrLine>
              <country key="ES"/>
            </address>
            <ref type="url">http://www.cicancer.org/es</ref>
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        <org type="institution" xml:id="struct-501252" status="VALID">
          <orgName>Spanish National Research Council [Santiago de Compostela]</orgName>
          <orgName type="acronym">CSIC</orgName>
          <desc>
            <address>
              <addrLine>The Heritage Laboratory (LaPa), laboratory, es (Tut.: Spanish National Research Council (CSIC)) - Santiago de Compostela Spain</addrLine>
              <country key="ES"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-450355" status="VALID">
          <orgName>University of Hull [United Kingdom]</orgName>
          <desc>
            <address>
              <addrLine>Cottingham Rd, Hull, Yorkshire HU6 7RX</addrLine>
              <country key="GB"/>
            </address>
            <ref type="url">https://www.hull.ac.uk/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-325570" status="INCOMING">
          <orgName>IMIM-Hospital del Mar</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-150185" status="VALID">
          <orgName>German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg]</orgName>
          <orgName type="acronym">DKFZ</orgName>
          <desc>
            <address>
              <addrLine>German Cancer Research Center Im Neuenheimer Feld 280 D-69120 Heidelberg</addrLine>
              <country key="DE"/>
            </address>
            <ref type="url">https://www.dkfz.de/en/index.html</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300681" status="VALID">
          <orgName>NASA</orgName>
          <desc>
            <address>
              <addrLine>www.nasa.gov</addrLine>
              <country key="US"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-340667" status="VALID">
          <idno type="ROR">https://ror.org/05dxps055</idno>
          <orgName>California Institute of Technology</orgName>
          <orgName type="acronym">CALTECH</orgName>
          <desc>
            <address>
              <addrLine>1200 East California Blvd, Pasadena, California 91125</addrLine>
              <country key="US"/>
            </address>
            <ref type="url">http://www.caltech.edu</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-312360" status="INCOMING">
          <orgName>Russian Academy of Medical Sciences</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-160209" status="VALID">
          <idno type="IdRef">067103545</idno>
          <idno type="ROR">https://ror.org/03613d656</idno>
          <orgName>Brno University of Technology  [Brno]</orgName>
          <orgName type="acronym">BUT</orgName>
          <date type="start">1899-09-19</date>
          <desc>
            <address>
              <addrLine>Antonínská 548/1601 90 BrnoCzech Republic</addrLine>
              <country key="CZ"/>
            </address>
            <ref type="url">https://www.vutbr.cz/en/</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>