<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of inserm-04169727</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-15T20:54:05+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Next generation antibacterial strategies for regenerative endodontic procedures: a scoping review</title>
            <author role="aut">
              <persName>
                <forename type="first">Marianne</forename>
                <surname>Leveque</surname>
              </persName>
              <idno type="halauthorid">2867675-0</idno>
              <affiliation ref="#struct-258552"/>
              <affiliation ref="#struct-194495"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Marie</forename>
                <surname>Guittat</surname>
              </persName>
              <idno type="halauthorid">2867676-0</idno>
              <affiliation ref="#struct-194495"/>
              <affiliation ref="#struct-300074"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Béatrice</forename>
                <surname>Thivichon-Prince</surname>
              </persName>
              <idno type="halauthorid">2633793-0</idno>
              <affiliation ref="#struct-194495"/>
              <affiliation ref="#struct-300074"/>
              <affiliation ref="#struct-258552"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Alicia</forename>
                <surname>Reuzeau</surname>
              </persName>
              <idno type="halauthorid">2867677-0</idno>
              <affiliation ref="#struct-258552"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Matthieu</forename>
                <surname>Eveillard</surname>
              </persName>
              <email type="md5">138b5324822f7216eef2ee96fe8b598c</email>
              <email type="domain">chu-angers.fr</email>
              <idno type="idhal" notation="string">matthieu-eveillard</idno>
              <idno type="idhal" notation="numeric">749535</idno>
              <idno type="halauthorid" notation="string">46146-749535</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-5916-3627</idno>
              <affiliation ref="#struct-1084841"/>
              <affiliation ref="#struct-151939"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Marjorie</forename>
                <surname>Faure</surname>
              </persName>
              <idno type="halauthorid">1172162-0</idno>
              <affiliation ref="#struct-258552"/>
              <affiliation ref="#struct-300074"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean‐christophe</forename>
                <surname>Farges</surname>
              </persName>
              <email type="md5">b9cf973ebc3e4f2e3f0f5858ffd354f5</email>
              <email type="domain">univ-lyon1.fr</email>
              <idno type="idhal" notation="numeric">1048287</idno>
              <idno type="halauthorid" notation="string">2867678-1048287</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-1321-9856</idno>
              <affiliation ref="#struct-258552"/>
              <affiliation ref="#struct-300074"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Raphaël</forename>
                <surname>Richert</surname>
              </persName>
              <email type="md5">d8da29cb6497e5bc8b72c381d19934b2</email>
              <email type="domain">insa-lyon.fr</email>
              <idno type="idhal" notation="string">raphael-richert</idno>
              <idno type="idhal" notation="numeric">1082430</idno>
              <idno type="halauthorid" notation="string">2079538-1082430</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-9298-1293</idno>
              <idno type="IDREF">https://www.idref.fr/251885712</idno>
              <affiliation ref="#struct-194495"/>
              <affiliation ref="#struct-300074"/>
              <affiliation ref="#struct-31214"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Mourad</forename>
                <surname>Bekhouche</surname>
              </persName>
              <idno type="halauthorid">619449-0</idno>
              <affiliation ref="#struct-194495"/>
              <affiliation ref="#struct-258552"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Maxime</forename>
                <surname>Ducret</surname>
              </persName>
              <email type="md5">f9da3cc311837be200a8a0a4ab580983</email>
              <email type="domain">univ-lyon1.fr</email>
              <idno type="idhal" notation="string">ducertma</idno>
              <idno type="idhal" notation="numeric">777952</idno>
              <idno type="halauthorid" notation="string">1026358-777952</idno>
              <idno type="IDREF">https://www.idref.fr/153571268</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-5462-6258</idno>
              <affiliation ref="#struct-194495"/>
              <affiliation ref="#struct-300074"/>
              <affiliation ref="#struct-258552"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Bibliothèque universitaire</forename>
                <surname>Nantes Université</surname>
              </persName>
              <email type="md5">0eb85f98f376329b770e5a56a48707a4</email>
              <email type="domain">univ-nantes.fr</email>
            </editor>
            <funder ref="#projanr-56315"/>
            <funder ref="#projanr-55859"/>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2025-06-05 15:32:20</date>
              <date type="whenModified">2025-10-03 03:06:40</date>
              <date type="whenReleased">2025-06-05 15:35:48</date>
              <date type="whenProduced">2023-07</date>
              <date type="whenEndEmbargoed">2025-06-05</date>
              <ref type="file" target="https://inserm.hal.science/inserm-04169727v1/document">
                <date notBefore="2025-06-05"/>
              </ref>
              <ref type="file" subtype="publisherPaid" n="1" target="https://inserm.hal.science/inserm-04169727v1/file/Int%20Endodontic%20J%20-%202023%20-%20Leveque%20-%20Next%20generation%20antibacterial%20strategies%20for%20regenerative%20endodontic%20procedures%20A.pdf" id="file-5099611-4410952">
                <date notBefore="2025-06-05"/>
              </ref>
              <ref type="externalLink" target="https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/iej.13958"/>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="141690">
                <persName>
                  <forename>Bibliothèque universitaire</forename>
                  <surname>Nantes Université</surname>
                </persName>
                <email type="md5">0eb85f98f376329b770e5a56a48707a4</email>
                <email type="domain">univ-nantes.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">inserm-04169727</idno>
            <idno type="halUri">https://inserm.hal.science/inserm-04169727</idno>
            <idno type="halBibtex">leveque:inserm-04169727</idno>
            <idno type="halRefHtml">&lt;i&gt;International Endodontic Journal&lt;/i&gt;, 2023, 57 (7), pp.804-814. &lt;a target="_blank" href="https://dx.doi.org/10.1111/iej.13958"&gt;&amp;#x27E8;10.1111/iej.13958&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">International Endodontic Journal, 2023, 57 (7), pp.804-814. &amp;#x27E8;10.1111/iej.13958&amp;#x27E9;</idno>
            <availability status="restricted">
              <licence target="https://creativecommons.org/licenses/by-nc-nd/4.0/">CC BY-NC-ND 4.0 - Attribution - Non-commercial use - No Derivative Works<ref corresp="#file-5099611-4410952"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="INSERM">INSERM - Institut national de la santé et de la recherche médicale</idno>
            <idno type="stamp" n="HCL">Hospices Civils de Lyon</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-LYON1">Université Claude Bernard - Lyon I</idno>
            <idno type="stamp" n="UNIV-ANGERS">Université d'Angers</idno>
            <idno type="stamp" n="INSA-LYON">Institut National des Sciences Appliquées de Lyon</idno>
            <idno type="stamp" n="LAMCOS" corresp="INSA-LYON">Laboratoire de Mécanique des Contacts et des Structures</idno>
            <idno type="stamp" n="INSA-GROUPE">Groupe INSA</idno>
            <idno type="stamp" n="UDL">UDL</idno>
            <idno type="stamp" n="UNIV-LYON">Université de Lyon</idno>
            <idno type="stamp" n="ANR">ANR</idno>
            <idno type="stamp" n="INCIT">Immunologie et nouveaux concepts en immunothérapie/Immunology and New Concepts in Immuno-Therapy</idno>
            <idno type="stamp" n="NANTES-UNIVERSITE">Nantes Université</idno>
            <idno type="stamp" n="NANTES-UNIV">Nantes Université</idno>
            <idno type="stamp" n="UFR-MEDECINE-NANTES">UFR de médecine - Nantes Université</idno>
            <idno type="stamp" n="LBTI">Laboratoire de Biologie Tissulaire et d’Ingénierie thérapeutique</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Next generation antibacterial strategies for regenerative endodontic procedures: a scoping review</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Marianne</forename>
                    <surname>Leveque</surname>
                  </persName>
                  <idno type="halauthorid">2867675-0</idno>
                  <affiliation ref="#struct-258552"/>
                  <affiliation ref="#struct-194495"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Marie</forename>
                    <surname>Guittat</surname>
                  </persName>
                  <idno type="halauthorid">2867676-0</idno>
                  <affiliation ref="#struct-194495"/>
                  <affiliation ref="#struct-300074"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Béatrice</forename>
                    <surname>Thivichon-Prince</surname>
                  </persName>
                  <idno type="halauthorid">2633793-0</idno>
                  <affiliation ref="#struct-194495"/>
                  <affiliation ref="#struct-300074"/>
                  <affiliation ref="#struct-258552"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Alicia</forename>
                    <surname>Reuzeau</surname>
                  </persName>
                  <idno type="halauthorid">2867677-0</idno>
                  <affiliation ref="#struct-258552"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Matthieu</forename>
                    <surname>Eveillard</surname>
                  </persName>
                  <email type="md5">138b5324822f7216eef2ee96fe8b598c</email>
                  <email type="domain">chu-angers.fr</email>
                  <idno type="idhal" notation="string">matthieu-eveillard</idno>
                  <idno type="idhal" notation="numeric">749535</idno>
                  <idno type="halauthorid" notation="string">46146-749535</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-5916-3627</idno>
                  <affiliation ref="#struct-1084841"/>
                  <affiliation ref="#struct-151939"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Marjorie</forename>
                    <surname>Faure</surname>
                  </persName>
                  <idno type="halauthorid">1172162-0</idno>
                  <affiliation ref="#struct-258552"/>
                  <affiliation ref="#struct-300074"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean‐christophe</forename>
                    <surname>Farges</surname>
                  </persName>
                  <email type="md5">b9cf973ebc3e4f2e3f0f5858ffd354f5</email>
                  <email type="domain">univ-lyon1.fr</email>
                  <idno type="idhal" notation="numeric">1048287</idno>
                  <idno type="halauthorid" notation="string">2867678-1048287</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-1321-9856</idno>
                  <affiliation ref="#struct-258552"/>
                  <affiliation ref="#struct-300074"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Raphaël</forename>
                    <surname>Richert</surname>
                  </persName>
                  <email type="md5">d8da29cb6497e5bc8b72c381d19934b2</email>
                  <email type="domain">insa-lyon.fr</email>
                  <idno type="idhal" notation="string">raphael-richert</idno>
                  <idno type="idhal" notation="numeric">1082430</idno>
                  <idno type="halauthorid" notation="string">2079538-1082430</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-9298-1293</idno>
                  <idno type="IDREF">https://www.idref.fr/251885712</idno>
                  <affiliation ref="#struct-194495"/>
                  <affiliation ref="#struct-300074"/>
                  <affiliation ref="#struct-31214"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Mourad</forename>
                    <surname>Bekhouche</surname>
                  </persName>
                  <idno type="halauthorid">619449-0</idno>
                  <affiliation ref="#struct-194495"/>
                  <affiliation ref="#struct-258552"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Maxime</forename>
                    <surname>Ducret</surname>
                  </persName>
                  <email type="md5">f9da3cc311837be200a8a0a4ab580983</email>
                  <email type="domain">univ-lyon1.fr</email>
                  <idno type="idhal" notation="string">ducertma</idno>
                  <idno type="idhal" notation="numeric">777952</idno>
                  <idno type="halauthorid" notation="string">1026358-777952</idno>
                  <idno type="IDREF">https://www.idref.fr/153571268</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-5462-6258</idno>
                  <affiliation ref="#struct-194495"/>
                  <affiliation ref="#struct-300074"/>
                  <affiliation ref="#struct-258552"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">14293</idno>
                <idno type="issn">0143-2885</idno>
                <idno type="eissn">1365-2591</idno>
                <title level="j">International Endodontic Journal</title>
                <imprint>
                  <publisher>Wiley</publisher>
                  <biblScope unit="volume">57</biblScope>
                  <biblScope unit="issue">7</biblScope>
                  <biblScope unit="pp">804-814</biblScope>
                  <date type="datePub">2023-07</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1111/iej.13958</idno>
              <idno type="pubmed">37485747</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">mesenchymal stem cells</term>
                <term xml:lang="en">regeneration</term>
                <term xml:lang="en">regenerative endodontic procedures</term>
                <term xml:lang="en">scoping review</term>
                <term xml:lang="en">tissue engineering</term>
                <term xml:lang="en">antibacterial strategies</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv">Life Sciences [q-bio]</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Background: The clinical results following regenerative endodontic procedures (REPs) vary according to numerous parameters, including the presence of bacteria. This limitation reduces the indications for REPs and calls for the development of next generation antibacterial strategies (NGAS) providing alternatives to current antibacterial strategies (CAS) such as double or triple antibiotic paste (DAP/TAP) and (Ca(OH)2).Objectives: The present scoping review aims to describe the current trends regarding the use of such strategies and highlight future perspectives.Methods: Four databases (PUBMed, Cochrane, ClinicalTrials and Science Direct) were searched until 1st May 2023.Results: A total of 918 records were identified, 133 were screened and assessed for eligibility, and 87 articles were included. The findings show that (1) clinical studies are only available for CAS, (2) although next generation strategies are the most studied approach since 2017, they are all at the pre-clinical stage, (3) most of the next generation strategies use galenic forms which offer cell support and colonization and which simultaneously contain antibacterial molecules as alternatives to CAS and to antibiotics in general, (4) standardization is required for future research, specifically regarding the bacterial strains studied, the use of biofilm studies and the cellular behaviour assessments.Conclusion: Although NGAS are promising strategies to improve REPs in the context of infection, the current evidence is mostly limited to pre-clinical studies. Further methodological improvement is required to allow relevant comparisons between studies and to reduce the time from bench to bedside.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-258552" status="VALID">
          <idno type="IdRef">175396108</idno>
          <idno type="ISNI">0000000404506543</idno>
          <idno type="RNSR">201320569F</idno>
          <idno type="ROR">04fqvqs63</idno>
          <orgName>Laboratoire de Biologie Tissulaire et d'ingénierie Thérapeutique</orgName>
          <orgName type="acronym">LBTI</orgName>
          <date type="start">2013-01-01</date>
          <desc>
            <address>
              <addrLine>7 Passage du Vercors 69367 Lyon cedex 07</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ibcp.fr/lbti/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-194495" type="direct"/>
            <relation active="#struct-301088" type="indirect"/>
            <relation name="UMR5305" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-194495" status="VALID">
          <idno type="IdRef">026402823</idno>
          <idno type="ISNI">0000000121686185</idno>
          <idno type="ROR">https://ror.org/029brtt94</idno>
          <orgName>Université Claude Bernard Lyon 1</orgName>
          <orgName type="acronym">UCBL</orgName>
          <desc>
            <address>
              <addrLine>43, boulevard du 11 novembre 1918, 69622 Villeurbanne cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-lyon1.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-301088" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-300074" status="VALID">
          <idno type="IdRef">026534657</idno>
          <idno type="ROR">https://ror.org/01502ca60</idno>
          <orgName>Hospices Civils de Lyon</orgName>
          <orgName type="acronym">HCL</orgName>
          <desc>
            <address>
              <addrLine>3 Quai des Célestins69002 Lyon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-1084841" status="VALID">
          <idno type="RNSR">202224154N</idno>
          <orgName>Immunology and New Concepts in ImmunoTherapy</orgName>
          <orgName type="acronym">INCIT</orgName>
          <date type="start">2022-01-01</date>
          <desc>
            <address>
              <addrLine>IRS2, 22 boulevard Benoni Goullin, 44200 Nantes</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://incit.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-74911" type="direct"/>
            <relation name="U1302" active="#struct-303623" type="direct"/>
            <relation name="EMR6001" active="#struct-441569" type="direct"/>
            <relation active="#struct-474972" type="direct"/>
            <relation active="#struct-1088522" type="direct"/>
            <relation active="#struct-1083368" type="indirect"/>
            <relation active="#struct-1083366" type="indirect"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-151939" status="VALID">
          <idno type="ISNI">0000 0004 0472 0283</idno>
          <idno type="ROR">https://ror.org/0250ngj72</idno>
          <orgName>Centre Hospitalier Universitaire d'Angers</orgName>
          <orgName type="acronym">CHU Angers</orgName>
          <desc>
            <address>
              <addrLine>4 rue Larrey - 49933 Angers cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-angers.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-31214" status="VALID">
          <idno type="IdRef">149703015</idno>
          <idno type="RNSR">200711924K</idno>
          <idno type="ROR">05s608j53</idno>
          <orgName>Laboratoire de Mécanique des Contacts et des Structures [Villeurbanne]</orgName>
          <orgName type="acronym">LaMCoS</orgName>
          <date type="start">2006-01-01</date>
          <desc>
            <address>
              <addrLine>Bâtiment Sophie Germain27b, avenue Jean CapelleF69621 VILLEURBANNE CEDEX</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://lamcos.insa-lyon.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-219748" type="direct"/>
            <relation active="#struct-301088" type="indirect"/>
            <relation active="#struct-301232" type="indirect"/>
            <relation name="UMR5259" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-301088" status="VALID">
          <idno type="ROR">https://ror.org/01rk35k63</idno>
          <orgName>Université de Lyon</orgName>
          <desc>
            <address>
              <addrLine>92 rue Pasteur - CS 30122, 69361 Lyon Cedex 07</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.universite-lyon.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-74911" status="VALID">
          <idno type="IdRef">026402920</idno>
          <idno type="ISNI">0000000122483363</idno>
          <idno type="ROR">https://ror.org/04yrqp957</idno>
          <orgName>Université d'Angers</orgName>
          <orgName type="acronym">UA</orgName>
          <date type="start">1971-10-25</date>
          <desc>
            <address>
              <addrLine>Université d'Angers - 40 Rue de Rennes, BP 73532 - 49035 Angers CEDEX 01</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-angers.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-474972" status="VALID">
          <idno type="IdRef">034926445</idno>
          <idno type="ROR">https://ror.org/05c1qsg97</idno>
          <idno type="Wikidata">Q2945767</idno>
          <orgName>Centre Hospitalier Universitaire de Nantes = Nantes University Hospital</orgName>
          <orgName type="acronym">CHU Nantes</orgName>
          <desc>
            <address>
              <addrLine>1 Place Alexis-Ricordeau, 44000 Nantes</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-nantes.fr</ref>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-1088522" status="VALID">
          <idno type="IdRef">076954927</idno>
          <orgName>Nantes Université - UFR de Médecine et des Techniques Médicales</orgName>
          <orgName type="acronym">Nantes Univ - UFR MEDECINE</orgName>
          <date type="start">2022-01-01</date>
          <desc>
            <address>
              <addrLine>1 rue Gaston Veil BP 53508 44035 NANTES Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.medecine.univ-nantes.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1083368" type="direct"/>
            <relation active="#struct-1083366" type="indirect"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-1083368" status="VALID">
          <orgName>Nantes Université - pôle Santé</orgName>
          <date type="start">2022-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://nouvelleuniversite.univ-nantes.fr/les-poles</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1083366" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-1083366" status="VALID">
          <idno type="IdRef">258086599</idno>
          <idno type="ROR">https://ror.org/03gnr7b55</idno>
          <orgName>Nantes Université</orgName>
          <orgName type="acronym">Nantes Univ</orgName>
          <date type="start">2022-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-219748" status="VALID">
          <idno type="IdRef">052444724</idno>
          <idno type="ISNI">0000 0001 2292 0228</idno>
          <orgName>Institut National des Sciences Appliquées de Lyon</orgName>
          <orgName type="acronym">INSA Lyon</orgName>
          <date type="start">1957-03-18</date>
          <desc>
            <address>
              <addrLine>20 Avenue Albert Einstein, 69621 Villeurbanne cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.insa-lyon.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-301088" type="direct"/>
            <relation active="#struct-301232" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-301232" status="VALID">
          <idno type="IdRef">162105150</idno>
          <orgName>Institut National des Sciences Appliquées</orgName>
          <orgName type="acronym">INSA</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
      </listOrg>
      <listOrg type="projects">
        <org type="anrProject" xml:id="projanr-56315" status="VALID">
          <idno type="anr">ANR-21-CE19-0001</idno>
          <orgName>ENDONANOBIOTIC</orgName>
          <desc>Un hydrogel antibactérien pour favoriser la régénération de la pulpe dentaire</desc>
          <date type="start">2021</date>
        </org>
        <org type="anrProject" xml:id="projanr-55859" status="VALID">
          <idno type="anr">ANR-21-CE44-0015</idno>
          <orgName>TRIDENTOMIC</orgName>
          <desc>Investigation multi-omique de la construction de matrice extracellulaire par les cellules souches humaines mésenchymateuses dans un hydrogel 3D de fibrine pour la régénération de la pulpe dentaire</desc>
          <date type="start">2021</date>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>