System engineering advocates a thorough under-standing of the engineering domain or certification standards (aeronautics, railway, medical, etc.) associated to the system under design. In this context, engineering domain knowledge plays a predominant role in system design and/or certification. Furthermore, it is a prerequisite to achieve the effectiveness and performance of the designed system. This article proposes a formal method for describing and setting up domain-specific behavioural analyses. It defines a formal verification technique for dynamic properties entailed by engineering domain knowledge where Event-B formal models are annotated and analysed in a non-intrusive way, i.e. without destructive alteration. This method is based on the formalisation of behavioural properties analyses relying on domain knowledge as an ontology on the one hand and a meta-theory for Event-B on the other hand. The proposed method is illustrated using a critical interactive system.