ERS statement on standardisation of cardiopulmonary exercise testing in chronic lung diseases
Thomas Radtke
(1, 2)
,
Sarah Crook
(1)
,
Georgios Kaltsakas
(3, 4)
,
Zafeiris Louvaris
(5, 6)
,
Danilo Berton
(7)
,
Don Urquhart
(8)
,
Asterios Kampouras
(9)
,
Roberto Rabinovich
(10, 11)
,
Samuel Verges
(12)
,
Dimitris Kontopidis
(13)
,
Jeanette Boyd
(14)
,
Thomy Tonia
(15)
,
Daniel Langer
(5, 6)
,
Jana de Brandt
(16)
,
Yvonne M.J. Goërtz
(17)
,
Chris Burtin
(16)
,
Martijn Spruit
(16, 17, 18)
,
Dionne C.W. Braeken
(17)
,
Sauwaluk Dacha
(5, 6, 19)
,
Frits M.E. Franssen
(17, 18)
,
Pierantonio Laveneziana
(20, 21)
,
Ernst Eber
(22)
,
Thierry Troosters
(6, 23)
,
J. Alberto Neder
(24)
,
Milo Puhan
(1)
,
Richard Casaburi
(25)
,
Ioannis Vogiatzis
(4, 26)
,
Helge Hebestreit
(27)
1
UZH -
Universität Zürich [Zürich] = University of Zurich
2 University hospital of Zurich [Zurich]
3 Guy's and St Thomas' NHS Foundation Trust [London, UK]
4 NKUA - National and Kapodistrian University of Athens
5 University Hospitals Leuven [Leuven]
6 KU Leuven - Technologie campus Gent - KU Leuven
7 UFRGS - Universidade Federal do Rio Grande do Sul [Porto Alegre]
8 Royal Hospital for Sick Children [Edinburgh]
9 424 GMTH - 424 General Military Training Hospital [Thessaloniki, Greece]
10 Edin. - University of Edinburgh
11 Royal Infirmary of Edinburgh
12 HP2 - Hypoxie et PhysioPathologie
13 HCFA - Hellenic Cystic Fibrosis Association [Athens, Greece]
14 ELF - The European Lung Foundation
15 UNIBE - Universität Bern / University of Bern
16 UHasselt - Hasselt University
17 CIRO [Horn, The Netherlands]
18 MUMC - Maastricht University Medical Centre
19 CMU - Chiang Mai University
20 UMRS 1158 - Neurophysiologie Respiratoire Expérimentale et Clinique
21 CHU Pitié-Salpêtrière [AP-HP]
22 Medical University of Graz
23 University Hospital Gasthuisberg [Leuven]
24 Queen's University [Kingston, Canada]
25 Harbor UCLA Medical Center [Torrance, Ca.]
26 Northumbria University [Newcastle]
27 University Hospital of Würzburg
2 University hospital of Zurich [Zurich]
3 Guy's and St Thomas' NHS Foundation Trust [London, UK]
4 NKUA - National and Kapodistrian University of Athens
5 University Hospitals Leuven [Leuven]
6 KU Leuven - Technologie campus Gent - KU Leuven
7 UFRGS - Universidade Federal do Rio Grande do Sul [Porto Alegre]
8 Royal Hospital for Sick Children [Edinburgh]
9 424 GMTH - 424 General Military Training Hospital [Thessaloniki, Greece]
10 Edin. - University of Edinburgh
11 Royal Infirmary of Edinburgh
12 HP2 - Hypoxie et PhysioPathologie
13 HCFA - Hellenic Cystic Fibrosis Association [Athens, Greece]
14 ELF - The European Lung Foundation
15 UNIBE - Universität Bern / University of Bern
16 UHasselt - Hasselt University
17 CIRO [Horn, The Netherlands]
18 MUMC - Maastricht University Medical Centre
19 CMU - Chiang Mai University
20 UMRS 1158 - Neurophysiologie Respiratoire Expérimentale et Clinique
21 CHU Pitié-Salpêtrière [AP-HP]
22 Medical University of Graz
23 University Hospital Gasthuisberg [Leuven]
24 Queen's University [Kingston, Canada]
25 Harbor UCLA Medical Center [Torrance, Ca.]
26 Northumbria University [Newcastle]
27 University Hospital of Würzburg
Thomas Radtke
- Fonction : Auteur
- PersonId : 1170688
- ORCID : 0000-0002-1723-1070
Don Urquhart
- Fonction : Auteur
- PersonId : 1170689
- ORCID : 0000-0002-9048-9692
Asterios Kampouras
- Fonction : Auteur
- PersonId : 1170690
- ORCID : 0000-0001-7047-9449
Daniel Langer
- Fonction : Auteur
- PersonId : 1170691
- ORCID : 0000-0001-8738-9482
Martijn Spruit
- Fonction : Auteur
- PersonId : 1170692
- ORCID : 0000-0003-3822-7430
Frits M.E. Franssen
- Fonction : Auteur
- PersonId : 1170693
- ORCID : 0000-0002-1633-6356
J. Alberto Neder
- Fonction : Auteur
- PersonId : 1170687
- ORCID : 0000-0002-8019-281X
Milo Puhan
- Fonction : Auteur
- PersonId : 1170694
- ORCID : 0000-0003-4721-1879
Résumé
The objective of this document was to standardise published cardiopulmonary exercise testing (CPET) protocols for improved interpretation in clinical settings and multicentre research projects. This document: 1) summarises the protocols and procedures used in published studies focusing on incremental CPET in chronic lung conditions; 2) presents standard incremental protocols for CPET on a stationary cycle ergometer and a treadmill; and 3) provides patients' perspectives on CPET obtained through an online survey supported by the European Lung Foundation. We systematically reviewed published studies obtained from EMBASE, Medline, Scopus, Web of Science and the Cochrane Library from inception to January 2017. Of 7914 identified studies, 595 studies with 26 523 subjects were included. The literature supports a test protocol with a resting phase lasting at least 3 min, a 3-min unloaded phase, and an 8- to 12-min incremental phase with work rate increased linearly at least every minute, followed by a recovery phase of at least 2–3 min. Patients responding to the survey (n=295) perceived CPET as highly beneficial for their diagnostic assessment and informed the Task Force consensus. Future research should focus on the individualised estimation of optimal work rate increments across different lung diseases, and the collection of robust normative data.