The impact of transposable elements on tomato diversity - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Nature Communications Year : 2020

The impact of transposable elements on tomato diversity

Abstract

Tomatoes come in a multitude of shapes and flavors despite a narrow genetic pool. Here, we leverage whole-genome resequencing data available for 602 cultivated and wild accessions to determine the contribution of transposable elements (TEs) to tomato diversity. We identify 6,906 TE insertions polymorphisms (TIPs), which result from the mobilization of 337 distinct TE families. Most TIPs are low frequency variants and TIPs are disproportionately located within or adjacent to genes involved in environmental responses. In addition, genic TE insertions tend to have strong transcriptional effects and they can notably lead to the generation of multiple transcript isoforms. Using genome-wide association studies (GWAS), we identify at least 40 TIPs robustly associated with extreme variation in major agronomic traits or secondary metabolites and in most cases, no SNP tags the TE insertion allele. Collectively, these findings highlight the unique role of TE mobilization in tomato diversification, with important implications for breeding.
Fichier principal
Vignette du fichier
s41467-020-17874-2.pdf (3.25 Mo) Télécharger le fichier
Origin : Publication funded by an institution
Loading...

Dates and versions

inserm-02950930 , version 1 (28-09-2020)

Licence

Attribution

Identifiers

Cite

Marisol Domínguez, Elise Dugas, Médine Benchouaia, Basile Leduque, José M Jiménez-Gómez, et al.. The impact of transposable elements on tomato diversity. Nature Communications, 2020, 11 (1), pp.4058. ⟨10.1038/s41467-020-17874-2⟩. ⟨inserm-02950930⟩
148 View
116 Download

Altmetric

Share

Gmail Facebook X LinkedIn More