Allergy immunotherapy across the life cycle to promote active and healthy ageing: from research to policies: An AIRWAYS Integrated Care Pathways (ICPs) programme item (Action Plan B3 of the European Innovation Partnership on active and healthy ageing) and the Global Alliance against Chronic Respiratory Diseases (GARD), a World Health Organization GARD research demonstration project
Moisés A Calderon
(1)
,
Pascal Demoly
(2, 3)
,
Thomas Casale
(4)
,
Cezmi A Akdis
(5)
,
Claus Bachert
(6)
,
Michael Bewick
(7)
,
Maria Beatrice Bilò
(8)
,
Barbara Bohle
(9)
,
Sergio Bonini
(10, 11)
,
A Bush
(1)
,
Davide P Caimmi
(2, 3)
,
Giorgio Walter Canonica
(12)
,
Victoria Cardona
(13)
,
Anca Mirela Chiriac
(2, 3)
,
Linda Cox
(14)
,
Adnan Custovic
(1)
,
Frédéric de Blay
(15)
,
Philippe Devillier
(16)
,
Alain Didier
(17)
,
Gabriele Di Lorenzo
(18, 19, 20)
,
George Du Toit
(19)
,
Stephen R Durham
(1)
,
Peter Eng
(21)
,
Alessandro Fiocchi
(22)
,
A. T. Fox
(19)
,
Roy Gerth van Wijk
(23)
,
R. M. Gomez
(24)
,
Tari Haathela
(25)
,
Susanne Halken
(26)
,
Peter W Hellings
(27)
,
Lars Jacobsen
(28)
,
Jocelyne Just
(2, 18)
,
Luciana K Tanno
(2, 29, 30)
,
J. Kleine-Tebbe
(31)
,
Ludger Klimek
(32)
,
Edward F Knol
(33)
,
Piotr Kuna
(34)
,
Désirée E Larenas-Linnemann
(35, 36)
,
Allan Linneberg
(37, 38, 39)
,
M. Matricardi
(40)
,
Hans-Joergen Malling
(41)
,
Ralph Moesges
(42)
,
Joaquim Mullol
(43)
,
Antonella Muraro
(44)
,
Nikos Papadopoulos
,
Giovanni Passalacqua
(12)
,
Elideanna Pastorello
(45)
,
Olivier Pfaar
(46, 47, 48)
,
David Price
(49, 50, 51)
,
Pablo Rodriguez del Rio
(52)
,
R. Ruëff
(53)
,
Boleslaw Samolinski
(54)
,
Glenis K Scadding
(55, 56)
,
Gabriela Senti
(57)
,
Mohamed H Shamji
(1, 58)
,
Aziz Sheikh
(59)
,
Juan Carlos Sisul
(60)
,
Dirceu Sole
(61)
,
Gunter J Sturm
(62, 63)
,
Ana Tabar
(64)
,
Ronald van Ree
(65)
,
Maria Teresa Ventura
(66)
,
Carmen Vidal
(67)
,
Eva Maria Varga
(62)
,
Margitta Worm
(40)
,
Torsten Zuberbier
(40)
,
Jean Bousquet
(68, 69)
1
Imperial College London
2 iPLESP - Institut Pierre Louis d'Epidémiologie et de Santé Publique
3 Service Pneumologie, Allergologie et Oncologie thoracique [Hôpital Arnaud de Villeneuve - CHU Montpellier]]
4 USF - University of South Florida [Tampa]
5 UZH - Universität Zürich [Zürich] = University of Zurich
6 Ghent University Hospital
7 iQ4U consultants Ltd
8 University hospital Ospedali Riuniti
9 Medizinische Universität Wien = Medical University of Vienna
10 CNR - National Research Council of Italy | Consiglio Nazionale delle Ricerche
11 University of Naples Federico II = Università degli studi di Napoli Federico II
12 UniGe - Università degli studi di Genova = University of Genoa
13 Vall d'Hebron University Hospital [Barcelona]
14 NSU - Nova Southeastern University
15 Pôle de pathologie thoracique
16 LOBIP - Laboratoire de recherche sur les mécanismes moléculaires et pharmacologiques de l’obstruction bronchique
17 Pôle Clinique des Voies respiratoires [CHU Toulouse]
18 CHU Trousseau [APHP]
19 King‘s College London
20 Università degli studi di Palermo - University of Palermo
21 Children's hospital Aarau
22 IRCCS Ospedale Pediatrico Bambino Gesù = Bambino Gesù Children’s Hospital
23 Erasmus MC - Erasmus University Medical Center [Rotterdam]
24 Hospital San Bernardo
25 HUS - Helsinki University Hospital [Finland]
26 Odense University Hospital
27 University Hospitals Leuven [Leuven]
28 Allergy Learning and Consulting
29 CHU Montpellier
30 Hospital Sírio Libanês
31 Allergy and Asthma Center Westend
32 German Society for Otorhinolaryngology HNS
33 UMCU - University Medical Center [Utrecht]
34 MUL - Medical University of Łódź
35 Hospital Medica Sur
36 ARIA
37 UCPH - University of Copenhagen = Københavns Universitet
38 RCPH - Research Centre for Prevention and Health
39 Rigshospitalet [Copenhagen]
40 Charité - UniversitätsMedizin = Charité - University Hospital [Berlin]
41 Gentofte University Hospital
42 Institute of Medical Statistics, Informatics and Epidemiology (IMSIE)
43 CIBERES - Centro de Investigación Biomédica en Red Enfermedades Respiratorias
44 Unipd - Università degli Studi di Padova = University of Padua
45 ASST Grande Ospedale Metropolitano Niguarda
46 Universität Mannheim
47 Center for Rhinology and Allergology = Zentrum für Rhinologie und Allergologie
48 University Medical Centre Mannheim
49 University of Aberdeen
50 RiRL - Research in Real Life
51 Optimum Patient Care Ltd, Singapore
52 HIUNJ - Hospital Infantil Universitario Niño Jesús
53 Ludwig-Maximillians University
54 Medical University of Warsaw - Poland
55 UCL - University College of London [London]
56 Royal National Throat, Nose and Ear Institute
57 University hospital of Zurich [Zurich]
58 MRC and Asthma UK Centre in Allergic Mechanisms of Asthma
59 Edin. - University of Edinburgh
60 SLaai - Sociedad Latinoamericana de alergia, asma e inmunolgia
61 Unifesp - Federal University of Sao Paulo
62 Medical University of Graz = Medizinische Universität Graz
63 Allergy Outpatient Clinic Reumannplatz
64 Complejo Hospitalario de Navarra
65 UvA - University of Amsterdam [Amsterdam] = Universiteit van Amsterdam
66 UNIBA - Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro
67 USC - Universidade de Santiago de Compostela [Spain]
68 VIMA - Vieillissement et Maladies chroniques : approches épidémiologique et de santé publique
69 MACVIA-LR - Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon
2 iPLESP - Institut Pierre Louis d'Epidémiologie et de Santé Publique
3 Service Pneumologie, Allergologie et Oncologie thoracique [Hôpital Arnaud de Villeneuve - CHU Montpellier]]
4 USF - University of South Florida [Tampa]
5 UZH - Universität Zürich [Zürich] = University of Zurich
6 Ghent University Hospital
7 iQ4U consultants Ltd
8 University hospital Ospedali Riuniti
9 Medizinische Universität Wien = Medical University of Vienna
10 CNR - National Research Council of Italy | Consiglio Nazionale delle Ricerche
11 University of Naples Federico II = Università degli studi di Napoli Federico II
12 UniGe - Università degli studi di Genova = University of Genoa
13 Vall d'Hebron University Hospital [Barcelona]
14 NSU - Nova Southeastern University
15 Pôle de pathologie thoracique
16 LOBIP - Laboratoire de recherche sur les mécanismes moléculaires et pharmacologiques de l’obstruction bronchique
17 Pôle Clinique des Voies respiratoires [CHU Toulouse]
18 CHU Trousseau [APHP]
19 King‘s College London
20 Università degli studi di Palermo - University of Palermo
21 Children's hospital Aarau
22 IRCCS Ospedale Pediatrico Bambino Gesù = Bambino Gesù Children’s Hospital
23 Erasmus MC - Erasmus University Medical Center [Rotterdam]
24 Hospital San Bernardo
25 HUS - Helsinki University Hospital [Finland]
26 Odense University Hospital
27 University Hospitals Leuven [Leuven]
28 Allergy Learning and Consulting
29 CHU Montpellier
30 Hospital Sírio Libanês
31 Allergy and Asthma Center Westend
32 German Society for Otorhinolaryngology HNS
33 UMCU - University Medical Center [Utrecht]
34 MUL - Medical University of Łódź
35 Hospital Medica Sur
36 ARIA
37 UCPH - University of Copenhagen = Københavns Universitet
38 RCPH - Research Centre for Prevention and Health
39 Rigshospitalet [Copenhagen]
40 Charité - UniversitätsMedizin = Charité - University Hospital [Berlin]
41 Gentofte University Hospital
42 Institute of Medical Statistics, Informatics and Epidemiology (IMSIE)
43 CIBERES - Centro de Investigación Biomédica en Red Enfermedades Respiratorias
44 Unipd - Università degli Studi di Padova = University of Padua
45 ASST Grande Ospedale Metropolitano Niguarda
46 Universität Mannheim
47 Center for Rhinology and Allergology = Zentrum für Rhinologie und Allergologie
48 University Medical Centre Mannheim
49 University of Aberdeen
50 RiRL - Research in Real Life
51 Optimum Patient Care Ltd, Singapore
52 HIUNJ - Hospital Infantil Universitario Niño Jesús
53 Ludwig-Maximillians University
54 Medical University of Warsaw - Poland
55 UCL - University College of London [London]
56 Royal National Throat, Nose and Ear Institute
57 University hospital of Zurich [Zurich]
58 MRC and Asthma UK Centre in Allergic Mechanisms of Asthma
59 Edin. - University of Edinburgh
60 SLaai - Sociedad Latinoamericana de alergia, asma e inmunolgia
61 Unifesp - Federal University of Sao Paulo
62 Medical University of Graz = Medizinische Universität Graz
63 Allergy Outpatient Clinic Reumannplatz
64 Complejo Hospitalario de Navarra
65 UvA - University of Amsterdam [Amsterdam] = Universiteit van Amsterdam
66 UNIBA - Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro
67 USC - Universidade de Santiago de Compostela [Spain]
68 VIMA - Vieillissement et Maladies chroniques : approches épidémiologique et de santé publique
69 MACVIA-LR - Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon
Pascal Demoly
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Cezmi A Akdis
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Barbara Bohle
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Davide P Caimmi
- Fonction : Auteur
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- ORCID : 0000-0003-4481-6194
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Giorgio Walter Canonica
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Philippe Devillier
- Fonction : Auteur
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Alain Didier
- Fonction : Auteur
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- ORCID : 0000-0001-6230-9706
Gabriele Di Lorenzo
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Alessandro Fiocchi
- Fonction : Auteur
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Roy Gerth van Wijk
- Fonction : Auteur
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Jocelyne Just
- Fonction : Auteur
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Luciana K Tanno
- Fonction : Auteur
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- IdHAL : luciana-kase-tanno
- ORCID : 0000-0003-3236-1225
- IdRef : 248787136
Allan Linneberg
- Fonction : Auteur
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M. Matricardi
- Fonction : Auteur
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Ralph Moesges
- Fonction : Auteur
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Joaquim Mullol
- Fonction : Auteur
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Antonella Muraro
- Fonction : Auteur
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Nikos Papadopoulos
- Fonction : Auteur
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Giovanni Passalacqua
- Fonction : Auteur
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Elideanna Pastorello
- Fonction : Auteur
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Olivier Pfaar
- Fonction : Auteur
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David Price
- Fonction : Auteur
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Pablo Rodriguez del Rio
- Fonction : Auteur
- PersonId : 994679
Glenis K Scadding
- Fonction : Auteur
- PersonId : 938750
Mohamed H Shamji
- Fonction : Auteur
- PersonId : 994681
Juan Carlos Sisul
- Fonction : Auteur
- PersonId : 994682
Gunter J Sturm
- Fonction : Auteur
- PersonId : 994489
Ronald van Ree
- Fonction : Auteur
- PersonId : 894404
Maria Teresa Ventura
- Fonction : Auteur
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Eva Maria Varga
- Fonction : Auteur
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Margitta Worm
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Torsten Zuberbier
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Résumé
Allergic diseases often occur early in life and persist throughout life. This life-course perspective should be considered in allergen immunotherapy. In particular it is essential to understand whether this al treatment may be used in old age adults. The current paper was developed by a working group of AIRWAYS integrated care pathways for airways diseases, the model of chronic respiratory diseases of the European Innovation Partnership on active and healthy ageing (DG CONNECT and DG Santé). It considered (1) the political background, (2) the rationale for allergen immunotherapy across the life cycle, (3) the unmet needs for the treatment, in particular in preschool children and old age adults, (4) the strategic framework and the practical approach to synergize current initiatives in allergen immunotherapy, its mechanisms and the concept of active and healthy ageing.
Domaines
Sciences du Vivant [q-bio]Origine | Fichiers éditeurs autorisés sur une archive ouverte |
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