%0 Journal Article %T Surgical treatment of bronchial asthma by resection of the laryngeal nerve %+ Department of Plastic, Reconstructive Microsurgery and Regenerative Medicine %+ Carcinose Angiogenèse et Recherche Translationnelle ; Angiogenese et recherche translationnelle (CART U965) %A Kurbon, Ubaidullo %A Dodariyon, Hamza %A Davlatov, Abdumalik %A Janobilova, Sitora %A Therwath, Amu %A Mirshahi, Massoud %< avec comité de lecture %@ 1471-2482 %J BMC Surgery %I BioMed Central %V 15 %N 1 %P 109 %8 2015-12 %D 2015 %R 10.1186/s12893-015-0093-2 %K Asthma %K Asphyxias %K Laryngeal nerve %K Surgical resection %Z Life Sciences [q-bio]Journal articles %X AbstractBackgroundManagement of asthma in chronically affected patients is a serious health problem. Our aim was to show that surgical treatment of chronic bronchial asthma by unilateral resection of the internal branch of the superior laryngeal nerve (ib-SLN) is an adequateand lasting remedial response.Patients and methodsIn a retrospective study, 41 (26 male and 15 female) patients with bronchial chronic asthma were treated surgically during the period between 2005 and 2013. It consisted of a unilateral resection of the ib-SLN under optical zoom, on patients placed in supinator position. 35 patients (24 male and 11 female) who were un-operated were included as a control.ResultsIn all patients, medication was reduced progressively. When the results were compared with the control group, it was seen that in 26 % of the patients, both forced expiratory volume (FEV) and peak expiratory flow (PEF) increased significantly (p <05) and only modestly in 53.6 % of patients (FEV, p <05 and PEF, p <05). In the remaining 20 % of patients, these parameters remained however unchanged. Overall, in 80 % of patients unilateral resection of the ib-SLN gave satisfactory results because it shortened the intervals and duration of asthmatic attacks, rendering thereby a reduction in medication.ConclusionThis minimal-invasive method helped prevent/cure asphyxias in chronic bronchial asthma without affecting cough reflex,respiratory control and phonation and it helped patients avoid severe crisis. This approach is of interest for patients with severe and/or uncontrolled bronchial asthma in settings with limited access to drug treatment. %G English %2 https://inserm.hal.science/inserm-01264486/document %2 https://inserm.hal.science/inserm-01264486/file/12893_2015_Article_93.pdf %L inserm-01264486 %U https://inserm.hal.science/inserm-01264486 %~ INSERM %~ UNIV-PARIS7 %~ UNIV-PARIS