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["Table S14A. CNV-based"]
["Column","Description"]
["SampleID","AGP sample ID"]
["ancestry","estimated ancestry based on genotypes"]
["chr","chromosome"]
["start","hg18 coordinates of the start of the CNV"]
["end","hg18 coordinates of the end of the CNV"]
["CNV_type","deletion or duplication"]
["size","size of the CNV in bp"]
["refseq_exon_w00kb","Refseq genes whose exons are encompassed by the CNV"]
["NetBag1g_69g_w10kbfk","NETBAG selection of 1 gene per CNV (CNV definition includes a 10kb flanking region)"]
["NetBag2g_113g_w10kbfk","NETBAG selection of 2 genes per CNV (CNV definition includes a 10kb flanking region)"]
["FMRP_Darnell","CNV genes that are FMRP-targets; overlaps with Darnell et al. PMID:21784246, n=842"]
["FMRP_Ascano","CNV genes that are FMRP-targets; overlaps with Ascano et al. PMID:23235829, n=939"]
["Synapse_Grant-full","CNV genes that are postsynaptic density genes; according to Bayes et al. 2011, PMID: 21170055; full datatset n=1453g"]
["ExprBspan_BrainAny_log2rpkm3.0","CNV genes that are highly expressed in brain  (defined as log RPKM>3; BrainSpan n=10106"]
["ExprBspan_BrainAny_log2rpkm4.5","CNV genes that are highly expressed in brain  (defined as log RPKM>4.5; BrainSpan n=5610)"]
["ExprBspan_NotBrainExprF","CNV genes that are functionally-characterized as 'control genes not expressed in brain' (defined as log RPKM<1; BrainSpan n=5410)"]
["hi015","CNV genes with haploinsufficiency index above 0.15 as reported by Huang et al. PMID:20976243, n=8862"]
["hi035","CNV genes haploinsufficiency index above 0.35 as reported by Huang et al. PMID:20976243, n=4136"]
["hi055","CNV genes haploinsufficiency index above 0.55 as reported by Huang et al. PMID:20976243, n=2214"]
["NeuroF","NeuroF=Neuro Functional=Candidate gense according to manual curation of Gene Ontology terms and pathways"]
["NeuroF_EM","NeuroF_EM=NeuroFunctional_Enrichment-Map=Candidate genes according to gene-sets found associated by logistic regression test (main Figure 4A). Clusters considered: (a) Cell projection/Neural development/Axonogenesis, or (b) Neuronal synapse"]
["Development_EM","Genes belonging to the cluster Development/Cell Proliferation/Cell Motility in the enrichment map (EM; main Figure 4A)"]
["Candidate_stringent","Candidate genes that are clearly linked to synaptic components and/or autosomal dominant neurodevelopmental/neuropsychiatric phenotypes; see Pages 5-6 of the Supplement for definition"]
["Candidate_broad","Candidate genes that are linked to synaptic components, or neurodevelopmental/neuropsychiatric phenotypes, or brain expression; see Pages 5-6 of the Supplement for definition"]
["Candidate_broad_dev","Candidate genes that belong to gene-sets corresponding to broader developmental functions found by the logistic regression gene-set test and enrichment map clusters; see Pages 5-6 of the Supplement for definition"]
["Dominant ASD/ID_genes","Genes known for causing ASD and/or ID when mutated (Table S6)"]
[]
["Table S14B. Gene-characterization"]
["Color code of candidacy "]
[null,"Clear-cut neurodevelopmental disorder has been established"]
[null,"Evidence from SNV exome studies"]
[null,"There are a few reports of deletions or point mutations in cases but needs larger cohorts to become clear-cut. Priority to mouse genes with dominant phenotype, especially if dominant and relevant to autism, even if not yet reported in human disease"]
[null,"Impact in the development of CNS or early neurodegeneration supported by the literature"]
[null,"Impact in the development of CNS or early neurodegeneration, mostly based on MGI"]
[null,"Some evidence of impact in neurological disease"]
[null,"Little evidence of impact in neurological disease"]
[null,"Impact in the development (non-neuro)"]
[]
["Column","Description"]
["sampleID|chr#:star-end","unique CNV identifier"]
["NetBag2g_113g_w10kbfk","NETBAG selection of 2 genes per CNV (CNV definition includes a 10kb flanking region)"]
["Function (EntrezGene or OMIM)","Gene function, sources are 'EntrezGene' and/or 'OMIM'"]
["Known.ASD/ ID.genes","Genes known for causing ASD and/or ID when mutated"]
["LOF.dn.SNV","Genes with de novo LoF mutations;  evidence derived from whole-exome sequencing studies in medium size cohorts of ASD and/or ID cases"]
["rec.SNV consang.fams","Genes with homozygous or compound heterozygous mutations;  evidence derived from whole-exome sequencing studies in medium size cohorts of ASD and/or ID cases"]
["Neurodevelop disorder (empirical)","Support from at least one of the following sources: PubMed, MGI, networks"]
["Neurological disorder (empirical)","With involvement of the central or peripheral nervous system"]
["Non-neuro develop disorder (empirical)","Without involvement of the central or peripheral nervous system"]
["Disease (GeneReviews)","Disease-associated; based on GeneReviews"]
["OMIM (morbid)","Disease-associated; based on OMIM"]
["#HPO_het_dom_Gene_symbol","Gene listed in Human Phenotype Ontology as causing disease in dominant fashion"]
["#HPO_hom_rec_Gene_symbol","Gene listed in Human Phenotype Ontology as causing disease in recessive fashion"]
["#HPO_x_XL_Gene_symbol","Gene listed in Human Phenotype Ontology as causing disease in XL fashion"]
["Literature","Evidence from PubMed (literature search)"]
["PMID","PubMed ID"]
["MGI","Mouse Genome Informatics"]
["#MPO_het_dom_Gene_symbol","Gene listed in Mouse Phenotype Ontology as causing disease in dominant fashion"]
["#MPO_hom_rec_Gene_symbol","Gene listed in Mouse Phenotype Ontology as causing disease in recessive fashion"]
["#MPO_x_XL_Gene_symbol","Gene listed in Mouse Phenotype Ontology as causing disease in XL fashion"]
["mouse-neuro-phenotypes","Neurological presentation in the KO mouse"]
["Synapse_Grant-full","CNV genes that are postsynaptic density genes; according to Bayes et al. 2011, PMID: 21170055; full datatset n=1453g"]
["Synapse_Grant-consensus","CNV genes that are postsynaptic density genes; according to Bayes et al.  2011, PMID: 21170055; consensus datatset n=747g"]
["FMRP_Darnell","CNV genes that are FMRP-targets; overlaps with Darnell et al. PMID:21784246, n=842"]
["FMRP_Ascano","CNV genes that are FMRP-targets; overlaps with Ascano et al. PMID:23235829, n=939"]
["Brain_RNAseq.Exp.Levels_NCX","gene-expression level in the Neocortex"]
["Brain_RNAseq.Stage_NCX","gene-expression level in the Neocortex throughout development; prenatal vs. postnatal vs. unbiased"]
["#CNVdisrupted-by-105dn","Gene disrupted by CNV"]
["CNVtype_w_disrupted","CNV type (deletion or duplication)"]
["DEL/DUPdisrupt_OR_DEL-pHI>0.35","Gene disrupted OR deleted with a haploinsufficiency index above 0.35"]
["Haploinsufficiency Index","Haploinsufficiency index as reported in Huang et al., PMID:20976243"]
["Mechanism","Mechanism underlying the CNV formation"]
["GeneMania","Protein-protein direct interactions between the candidate gene and known morbid genes, as reported by GeneMania"]
["STRING","Protein-protein direct interactions between the candidate gene and known morbid genes, as reported by STRING"]
["NeuroF","NeuroF=Neuro Functional=Candidate gene according to manual curation of Gene Ontology terms and pathways"]
["NeuroF_EM","NeuroF_EM=NeuroFunctional_Enrichment-Map=Candidate genes according to gene-sets found associated by logistic regression test (main Figure 4A). Clusters considered: (a) Cell projection/Neural development/Axonogenesis, or (b) Neuronal synapse"]
["Development_EM","Genes belonging to the cluster Development/Cell Proliferation/Cell Motility in the enrichment map (EM; main Figure 4A)"]
["Candidate_stringent","Candidate genes that are clearly linked to synaptic components and/or autosomal dominant neurodevelopmental/neuropsychiatric phenotypes; see Pages 5-6 of the Supplement for definition"]
["Candidate_broad","Candidate genes that are linked to synaptic components, or neurodevelopmental/neuropsychiatric phenotypes, or brain expression; see Pages 5-6 of the Supplement for definition"]
["Candidate_broad_dev","Candidate genes that belong to gene-sets corresponding to broader developmental functions found by the logistic regression gene-set test and enrichment map clusters; see Pages 5-6 of the Supplement for definition"]
[]
[]
["Table S14C. Gene candidacy tier"]
["Column","Description"]
["NetBag2g_113g_w10kbfk","NETBAG selection of 2 genes per CNV (CNV definition includes a 10kb flanking region)"]
["Dominant known disease_genes","Genes known for causing ASD and/or ID when mutated"]
["FMRP_Darnell","CNV genes that are FMRP-targets; overlaps with Darnell et al. PMID:21784246, n=842"]
["FMRP_Ascano","CNV genes that are FMRP-targets; overlaps with Ascano et al. PMID:23235829, n=939"]
["Synapse_Grant-full","CNV genes that are postsynaptic density genes; according to Bayes et al. 2011, PMID: 21170055; full datatset n=1453g"]
["ExprBspan_BrainAny_log2rpkm3.0","CNV genes that are highly expressed in brain  (defined as log RPKM>3; BrainSpan n=10106"]
["ExprBspan_BrainAny_log2rpkm4.5","CNV genes that are highly expressed in brain  (defined as log RPKM>4.5; BrainSpan n=5610)"]
["ExprBspan_NotBrainExprF","CNV genes that are functionally-characterized as 'control genes not expressed in brain' (defined as log RPKM<1; BrainSpan n=5410)"]
["hi015","CNV genes with haploinsufficiency index above 0.15 as reported by Huang et al. PMID:20976243, n=8862"]
["hi035","CNV genes haploinsufficiency index above 0.35 as reported by Huang et al. PMID:20976243, n=4136"]
["hi055","CNV genes haploinsufficiency index above 0.55 as reported by Huang et al. PMID:20976243, n=2214"]
["NeuroF","NeuroF=Neuro Functional=Candidate gense according to manual curation of Gene Ontology terms and pathways"]
["NeuroF_EM","NeuroF_EM=NeuroFunctional_Enrichment-Map=Candidate genes according to gene-sets found associated by logistic regression test (main Figure 4A). Clusters considered: (a) Cell projection/Neural development/Axonogenesis, or (b) Neuronal synapse"]
["Development_EM","Genes belonging to the cluster Development/Cell Proliferation/Cell Motility in the enrichment map (EM; main Figure 4A)"]
["Candidate_stringent","Candidate genes that are clearly linked to synaptic components and/or autosomal dominant neurodevelopmental/neuropsychiatric phenotypes; see Pages 5-6 of the Supplement for definition"]
["Candidate_broad","Candidate genes that are linked to synaptic components, or neurodevelopmental/neuropsychiatric phenotypes, or brain expression; see Pages 5-6 of the Supplement for definition"]
["Candidate_broad_dev","Candidate genes that belong to gene-sets corresponding to broader developmental functions found by the logistic regression gene-set test and enrichment map clusters; see Pages 5-6 of the Supplement for definition"]
[]
[]
["Table S14D. Over-representation analysis of genes selected by NETBAG (Functional Enrichment (FET test))"]
["Functional enrichment analysis of the 113 genes selected by NETBAG"]
["GsID","Gene set ID (GO term and patways)"]
["GsName","Gene set name"]
["P_Value","P value"]
["FDR_BH 10%","False Discovery Rate with Benjamini-Hochberg correction for multiple testing"]
["Symbols","Gene symbol"]
[]
["Table S14E. BrainDevExpr. Enr"]
["Enrichment testing of functional groups regarding brain expression throughout development"]

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["SampleID","ancestry","chr","start","end","CNV_type","size","refseq_exon_w00kb","NetBag1g_69g_w10kbfk","NetBag2g_113g_w10kbfk","FMRP_Darnell","FMRP_Ascano","Synapse_Grant-full","ExprBspan_BrainAny_log2rpkm3.0","ExprBspan_BrainAny_log2rpkm4.5","ExprBspan_NotBrainExprF","hi015","hi035","hi055","NeuroF","NeuroF_EM","Development_EM","Candidate_stringent","Candidate_broad","Candidate_broad_dev","Dominant ASD/ID_genes"]
["8658_201","european",1,98175622,100923952,"DEL",2748331,"AGL;CCDC76;CDC14A;DBT;FRRS1;GPR88;HIAT1;LOC100129620;LPPR4;LPPR5;LRRC39;MIR137;MIR553;PALMD;RTCD1;SASS6;SLC35A3;SNX7","DBT","DBT;RTCD1","LPPR4","-","AGL;DBT","GPR88;HIAT1;LPPR4;LPPR5;PALMD;SNX7","GPR88;LPPR4;LPPR5;SNX7","CDC14A;FRRS1;SASS6","AGL;CDC14A;DBT;FRRS1;GPR88;HIAT1;LRRC39;PALMD;SLC35A3;SNX7","AGL;CDC14A;GPR88;HIAT1;PALMD","CDC14A;GPR88;PALMD","LPPR4;PALMD","LPPR4;PALMD","CDC14A;PALMD","LPPR4","AGL;DBT;GPR88;LPPR4;PALMD;SNX7","AGL;CDC14A;DBT;GPR88;LPPR4;PALMD;SNX7","-"]
["9877_204","other",1,98247355,99645560,"DUP",1398206,"LOC100129620;LPPR4;LPPR5;MIR137;SNX7","-","-","LPPR4","-","-","LPPR4;LPPR5;SNX7","LPPR4;LPPR5;SNX7","-","SNX7","-","-","LPPR4","LPPR4","-","LPPR4","LPPR4;SNX7","LPPR4;SNX7","-"]
["14310_4270","european",1,105623065,105788728,"DUP",165664,"-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-"]
["14310_4270","european",1,105896243,106480692,"DUP",584450,"-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-"]
["1952_301","other",1,144500467,146336720,"DUP",1836254,"ACP6;BCL9;CHD1L;FMO5;GJA5;GJA8;GPR89B;GPR89C;LOC728989;NBPF11;NBPF24;PDIA3P;PDZK1P1;PRKAB2","PRKAB2","CHD1L;PRKAB2","-","-","-","BCL9;PRKAB2","BCL9","FMO5;GJA8;GPR89B;GPR89C;NBPF24","BCL9;GJA8;GPR89B;PRKAB2","BCL9;PRKAB2","BCL9;PRKAB2","GJA8","-","GJA5;PRKAB2","-","BCL9","BCL9;GJA5;PRKAB2","-"]
["16035_1571013001","european",1,144482933,146325557,"DUP",1842625,"ACP6;BCL9;CHD1L;FMO5;GJA5;GJA8;GPR89A;GPR89B;GPR89C;LOC728989;NBPF11;NBPF24;PDIA3P;PDZK1P1;PRKAB2","PRKAB2","CHD1L;PRKAB2","-","-","-","BCL9;PRKAB2","BCL9","FMO5;GJA8;GPR89A;GPR89B;GPR89C;NBPF24","BCL9;GJA8;GPR89B;PRKAB2","BCL9;PRKAB2","BCL9;PRKAB2","GJA8","-","GJA5;PRKAB2","-","BCL9","BCL9;GJA5;PRKAB2","-"]
["8635_201","european",1,144500467,146377870,"DEL",1877404,"ACP6;BCL9;CHD1L;FLJ39739;FMO5;GJA5;GJA8;GPR89A;GPR89B;GPR89C;LOC100130000;LOC728989;NBPF11;NBPF24;PDIA3P;PDZK1P1;PRKAB2","PRKAB2","CHD1L;PRKAB2","-","-","-","BCL9;PRKAB2","BCL9","FMO5;GJA8;GPR89A;GPR89B;GPR89C;NBPF24","BCL9;GJA8;GPR89B;PRKAB2","BCL9;PRKAB2","BCL9;PRKAB2","GJA8","-","GJA5;PRKAB2","-","BCL9","BCL9;GJA5;PRKAB2","-"]
["13135_1523","european",1,144838594,146308287,"DUP",1469694,"ACP6;BCL9;CHD1L;FMO5;GJA5;GJA8;GPR89B;GPR89C;LOC728989;NBPF11;NBPF24;PDIA3P;PDZK1P1;PRKAB2","PRKAB2","CHD1L;PRKAB2","-","-","-","BCL9;PRKAB2","BCL9","FMO5;GJA8;GPR89B;GPR89C;NBPF24","BCL9;GJA8;GPR89B;PRKAB2","BCL9;PRKAB2","BCL9;PRKAB2","GJA8","-","GJA5;PRKAB2","-","BCL9","BCL9;GJA5;PRKAB2","-"]
["13082_963","european",2,11712589,11741036,"DUP",28448,"NTSR2","NTSR2","NTSR2","-","-","-","NTSR2","NTSR2","-","-","-","-","NTSR2","-","-","-","NTSR2","NTSR2","-"]
["14068_1180","european",2,50493827,50677835,"DUP",184009,"NRXN1","NRXN1","NRXN1","NRXN1","-","NRXN1","NRXN1","NRXN1","-","-","-","-","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1"]
["13017_223","european",2,50539877,50730546,"DEL",190670,"NRXN1","NRXN1","NRXN1","NRXN1","-","NRXN1","NRXN1","NRXN1","-","-","-","-","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1"]
["13216_2383","european",2,50968208,51214171,"DEL",245964,"NRXN1","NRXN1","NRXN1","NRXN1","-","NRXN1","NRXN1","NRXN1","-","-","-","-","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1"]
["13153_1703","european",2,50990306,51222043,"DEL",231738,"NRXN1","NRXN1","NRXN1","NRXN1","-","NRXN1","NRXN1","NRXN1","-","-","-","-","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1"]
["13037_463","european",2,51002576,51157742,"DEL",155167,"NRXN1","NRXN1","NRXN1","NRXN1","-","NRXN1","NRXN1","NRXN1","-","-","-","-","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1","NRXN1"]
["5089_5","other",2,102292943,102345460,"DEL",52518,"IL1RL1","IL1RL1","IL1RL1","-","-","-","-","-","IL1RL1","-","-","-","-","-","-","-","-","-","-"]
["4260_1","european",2,119603876,119882278,"DUP",278403,"C1QL2;C2orf76;DBI;STEAP3","DBI","DBI;STEAP3","-","-","-","C1QL2;C2orf76;DBI","C1QL2;DBI","-","STEAP3","-","-","-","-","-","-","DBI","DBI","-"]
["13027_353","european",2,144837809,145315383,"DUP",155167,"DKFZp686O1327;ZEB2","ZEB2","ZEB2","ZEB2","-","-","ZEB2","ZEB2","-","ZEB2","ZEB2","ZEB2","ZEB2","-","ZEB2","ZEB2","ZEB2","ZEB2","ZEB2"]
["14414_5230","european",2,230486629,230547253,"DEL",60625,"FBXO36;TRIP12","TRIP12","TRIP12","TRIP12","-","-","TRIP12","-","-","FBXO36;TRIP12","TRIP12","TRIP12","-","-","-","TRIP12","TRIP12","TRIP12","-"]
["5220_3","european",3,19127998,19640299,"DUP",512302,"KCNH8","KCNH8","KCNH8","-","-","-","-","-","-","-","-","-","KCNH8","KCNH8","-","-","-","-","-"]
["3174_3","european",3,19921061,20096832,"DEL",175772,"C3orf48;EFHB;KAT2B;RAB5A","KAT2B","KAT2B;RAB5A","-","-","RAB5A","KAT2B;RAB5A","RAB5A","EFHB","RAB5A","RAB5A","RAB5A","RAB5A","RAB5A","KAT2B","RAB5A","RAB5A","KAT2B;RAB5A","-"]
["5245_3","european",3,117285007,117477191,"DEL",192185,"LSAMP","LSAMP","LSAMP","-","-","LSAMP","LSAMP","LSAMP","-","LSAMP","LSAMP","LSAMP","LSAMP","-","-","LSAMP","LSAMP","LSAMP","-"]
["8587_210","european",3,139760896,140127703,"DUP",366808,"CEP70;FAIM;PIK3CB","PIK3CB","CEP70;PIK3CB","-","-","-","CEP70;FAIM;PIK3CB","-","-","CEP70;PIK3CB","PIK3CB","PIK3CB","PIK3CB","PIK3CB","CEP70;PIK3CB","-","PIK3CB","CEP70;PIK3CB","-"]
["8588_201","european",3,195971510,197675831,"DEL",1704322,"ACAP2;APOD;C3orf21;LOC100507391;LOC401109;MIR570;MUC20;MUC4;OSTalpha;PCYT1A;PPP1R2;SDHAP1;SDHAP2;TCTEX1D2;TFRC;TM4SF19;TM4SF19-TCTEX1D2;TNK2;UBXN7;ZDHHC19","TNK2","PCYT1A;TNK2","TNK2","-","APOD","APOD;PPP1R2;TCTEX1D2;TFRC;TNK2;UBXN7","APOD;PPP1R2;TCTEX1D2;TNK2","MUC20;MUC4;TM4SF19;ZDHHC19","MUC4;PCYT1A;TCTEX1D2;TFRC;TNK2","PCYT1A;TFRC;TNK2","PCYT1A","APOD","APOD","APOD","TNK2","APOD;TFRC;TNK2","APOD;TFRC;TNK2","-"]
["8677_201","other",4,94659049,95289667,"DUP",630619,"ATOH1;GRID2","GRID2","ATOH1;GRID2","-","-","-","GRID2","GRID2","-","ATOH1;GRID2","ATOH1","ATOH1","ATOH1;GRID2","ATOH1","ATOH1","-","ATOH1;GRID2","ATOH1;GRID2","-"]
["6402_3","european",4,98781694,99627129,"DUP",845436,"C4orf37;RAP1GDS1;TSPAN5","RAP1GDS1","RAP1GDS1","-","-","RAP1GDS1","RAP1GDS1;TSPAN5","RAP1GDS1;TSPAN5","-","RAP1GDS1;TSPAN5","-","-","-","-","-","-","RAP1GDS1;TSPAN5","RAP1GDS1;TSPAN5","-"]
["8709_201","european",5,88588170,89505509,"DEL",917340,"MIR3660","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-"]
["5353_3","european",6,33399849,33512042,"DEL",112194,"CUTA;KIFC1;PHF1;SYNGAP1","SYNGAP1","CUTA;SYNGAP1","SYNGAP1","KIFC1","SYNGAP1","CUTA;KIFC1;PHF1;SYNGAP1","CUTA;KIFC1;PHF1;SYNGAP1","-","CUTA;KIFC1;PHF1;SYNGAP1","PHF1;SYNGAP1","PHF1","SYNGAP1","SYNGAP1","SYNGAP1","SYNGAP1","KIFC1;PHF1;SYNGAP1","KIFC1;PHF1;SYNGAP1","SYNGAP1"]
["18133_302","european",6,69540429,73375020,"DUP",3834592,"B3GAT2;BAI3;C6orf155;C6orf57;COL19A1;COL9A1;FAM135A;LMBRD1;MIR30A;MIR30C2;OGFRL1;RIMS1;SMAP1","RIMS1","SMAP1;RIMS1","-","-","RIMS1","B3GAT2;BAI3;C6orf57;FAM135A;LMBRD1;OGFRL1;RIMS1;SMAP1","B3GAT2;C6orf57;LMBRD1;OGFRL1;RIMS1;SMAP1","COL19A1","B3GAT2;BAI3;COL9A1;FAM135A;LMBRD1;RIMS1;SMAP1","BAI3;COL9A1;RIMS1","-","COL9A1;RIMS1","COL9A1;RIMS1","BAI3;COL9A1;SMAP1","-","BAI3;COL9A1;LMBRD1;RIMS1","BAI3;COL9A1;LMBRD1;RIMS1;SMAP1","-"]
["6248_3","european",6,86352577,86376159,"DEL",23583,"SNX14;SYNCRIP","SYNCRIP","SNX14;SYNCRIP","-","-","SYNCRIP","SNX14;SYNCRIP","SYNCRIP","-","SYNCRIP","SYNCRIP","SYNCRIP","-","-","-","SYNCRIP","SYNCRIP","SYNCRIP","-"]
["5386_3","other",6,156785155,158489874,"DEL",1704720,"ARID1B;MIR3692;SERAC1;SNX9;SYNJ2;ZDHHC14","SYNJ2","SNX9;SYNJ2","ARID1B","SNX9","SNX9","ARID1B;SYNJ2;ZDHHC14","ARID1B;ZDHHC14","-","SERAC1;SYNJ2","-","-","ARID1B;SYNJ2","SYNJ2","-","ARID1B;SNX9","ARID1B;SNX9;SYNJ2","ARID1B;SNX9;SYNJ2","-"]
["6164_3","european",6,160023074,160081618,"DUP",58545,"SOD2;WTAP","SOD2","SOD2;WTAP","-","-","-","SOD2;WTAP","SOD2;WTAP","-","SOD2;WTAP","SOD2","SOD2","SOD2","SOD2","SOD2","-","SOD2","SOD2","-"]
["8612_201","european",6,162588879,162629938,"DEL",41060,"PARK2","PARK2","PARK2","-","-","-","-","-","-","PARK2","-","-","PARK2","PARK2","-","-","-","PARK2","-"]
["8404_201","european",6,169136788,170761395,"DEL",1624608,"C6orf120;C6orf208;C6orf70;DLL1;FAM120B;LOC154449;NCRNA00242;PDCD2;PHF10;PSMB1;TBP;TCTE3;THBS2;WDR27","TBP","PSMB1;TBP","-","-","-","C6orf120;DLL1;FAM120B;PDCD2;PHF10;PSMB1;TBP;THBS2","DLL1;PDCD2;PSMB1","TCTE3","C6orf120;DLL1;PDCD2;PHF10;PSMB1;TBP;THBS2;WDR27","DLL1;PSMB1;TBP;THBS2","DLL1;PSMB1;TBP;THBS2","DLL1;PHF10;THBS2","DLL1","DLL1;PSMB1;THBS2","-","DLL1;PSMB1;TBP;THBS2","DLL1;PSMB1;TBP;THBS2","-"]
["8446_201","european",7,72344426,73782113,"DEL",1437688,"ABHD11;ABHD11-AS1;BAZ1B;BCL7B;CLDN3;CLDN4;CLIP2;DNAJC30;EIF4H;ELN;FKBP6;FZD9;GTF2I;GTF2IRD1;LAT2;LIMK1;MIR4284;MIR590;MLXIPL;NSUN5;RFC2;STX1A;TBL2;TRIM50;VPS37D;WBSCR22;WBSCR27;WBSCR28","LIMK1","BAZ1B;LIMK1","-","GTF2IRD1","CLIP2;STX1A","ABHD11;BAZ1B;BCL7B;CLIP2;DNAJC30;EIF4H;ELN;FZD9;GTF2I;GTF2IRD1;LIMK1;NSUN5;RFC2;STX1A;TBL2;VPS37D;WBSCR22","BAZ1B;BCL7B;CLIP2;DNAJC30;EIF4H;GTF2I;LIMK1;STX1A;VPS37D","FKBP6;LAT2;TRIM50;WBSCR28","BAZ1B;BCL7B;CLDN3;CLDN4;EIF4H;ELN;GTF2I;GTF2IRD1;LIMK1;MLXIPL;NSUN5;RFC2;STX1A;TBL2","BAZ1B;EIF4H;ELN;GTF2I;MLXIPL;NSUN5;RFC2;STX1A","ELN;MLXIPL;NSUN5;RFC2","FZD9;GTF2I;LIMK1;STX1A","FZD9;LIMK1;STX1A","BAZ1B;FKBP6;FZD9;GTF2I;GTF2IRD1;LIMK1;MLXIPL;RFC2","CLIP2;GTF2IRD1;STX1A","BAZ1B;CLIP2;EIF4H;ELN;FZD9;GTF2I;GTF2IRD1;LIMK1;MLXIPL;NSUN5;STX1A;WBSCR22","BAZ1B;CLIP2;EIF4H;ELN;FKBP6;FZD9;GTF2I;GTF2IRD1;LIMK1;MLXIPL;NSUN5;RFC2;STX1A;WBSCR22","-"]
["1960_301","european",7,102699832,102798745,"DEL",98914,"DNAJC2;DPY19L2P2;PMPCB;PSMC2;SLC26A5","PSMC2","PMPCB;PSMC2","-","DNAJC2","-","DNAJC2;PMPCB;PSMC2","PMPCB;PSMC2","SLC26A5","PMPCB;PSMC2;SLC26A5","PSMC2","PSMC2","SLC26A5","SLC26A5","DNAJC2;PSMC2;SLC26A5","-","DNAJC2;PSMC2;SLC26A5","DNAJC2;PSMC2;SLC26A5","-"]
["5370_3","european",7,153775586,153844747,"DEL",69162,"DPP6","DPP6","DPP6","-","-","DPP6","DPP6","DPP6","-","-","-","-","-","-","-","-","DPP6","DPP6","-"]
["5290_3","other",8,704383,1521910,"DUP",817528,"DLGAP2;LOC286083","DLGAP2","DLGAP2","DLGAP2","-","DLGAP2","-","-","-","DLGAP2","-","-","DLGAP2","-","-","DLGAP2","DLGAP2","DLGAP2","-"]
["1142_4","european",8,48631388,48802529,"DUP",171142,"KIAA0146","-","-","-","-","-","KIAA0146","-","-","-","-","-","-","-","-","-","-","-","-"]
["6321_3","european",8,65354366,66254869,"DEL",900504,"BHLHE22;CYP7B1;LOC100130155;LOC401463;MIR124-2","BHLHE22","BHLHE22;CYP7B1","-","-","-","BHLHE22","BHLHE22","-","CYP7B1","-","-","CYP7B1","CYP7B1","CYP7B1","-","BHLHE22","BHLHE22;CYP7B1","-"]
["8500_201","european",8,74692898,74967280,"DEL",274383,"STAU2;UBE2W","UBE2W","STAU2;UBE2W","-","-","-","STAU2;UBE2W","STAU2","-","STAU2;UBE2W","STAU2;UBE2W","-","-","-","-","-","STAU2","STAU2","-"]
["5032_4","european",9,98998,334508,"DEL",235511,"C9orf66;CBWD1;DOCK8;FOXD4","-","-","-","-","-","-","-","DOCK8;FOXD4","DOCK8","DOCK8","-","FOXD4","FOXD4","FOXD4","-","-","FOXD4","-"]
["13123_1403","european",9,98998,3682923,"DEL",3583926,"C9orf66;CBWD1;DMRT1;DMRT2;DMRT3;DOCK8;FLJ35024;FOXD4;KANK1;KCNV2;KIAA0020;RFX3;SMARCA2;VLDLR","SMARCA2","RFX3;SMARCA2","SMARCA2","VLDLR","-","KANK1;RFX3;SMARCA2;VLDLR","SMARCA2","DMRT1;DMRT2;DOCK8;FOXD4;KCNV2","DMRT1;DMRT2;DOCK8;KANK1;KCNV2;KIAA0020;RFX3;SMARCA2;VLDLR","DMRT1;DOCK8;KANK1;KCNV2;KIAA0020;RFX3;SMARCA2","KIAA0020;RFX3;SMARCA2","FOXD4;KCNV2;SMARCA2;VLDLR","FOXD4;KCNV2;RFX3;VLDLR","FOXD4;RFX3;SMARCA2;VLDLR","SMARCA2","KCNV2;SMARCA2;VLDLR","FOXD4;KCNV2;RFX3;SMARCA2;VLDLR","SMARCA2"]
["6246_4","european",9,9399606,9631169,"DEL",231564,"PTPRD","PTPRD","PTPRD","PTPRD","-","PTPRD","PTPRD","PTPRD","-","PTPRD","PTPRD","PTPRD","-","-","-","PTPRD","PTPRD","PTPRD","-"]
["14417_5260","european",9,117311405,117727764,"DEL",416360,"C9orf27","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-"]
["6259_3","european",9,139516033,140208462,"DEL",692430,"ARRDC1, C9orf37, CACNA1B, EHMT1, EHMT1-IT1, MIR602, MRPL41, PNPLA7, TUBBP5, WDR85, ZMYND19","CACNA1B","CACNA1B;EHMT1","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","EHMT1"]
["18172_302","other",10,34963905,35536952,"DUP",573048,"CREM;CUL2;PARD3","PARD3","CUL2;PARD3","-","PARD3","-","CREM;CUL2;PARD3","-","-","CREM;CUL2;PARD3","CREM;CUL2;PARD3","CREM;CUL2","PARD3","PARD3","CUL2","-","CREM;PARD3","CREM;CUL2;PARD3","-"]
["8534_201","european",10,45633089,51564756,"DEL",5931667,"AGAP4;AGAP6;AGAP7;AGAP8;AGAP9;ANTXRL;ANXA8;ANXA8L1;ANXA8L2;ARHGAP22;BMS1P1;BMS1P5;C10orf128;C10orf53;C10orf71;C10orf72;CHAT;CTSL1P2;DRGX;ERCC6;FAM170B;FAM21A;FAM21B;FAM25B;FAM25C;FAM25G;FAM35B;FAM35B2;FLJ31813;FRMPD2;FRMPD2P1;GDF10;GDF2;GPRIN2;LOC399753;LOC642826;LOC643650;LOC728407;LOC728643;LRRC18;MAPK8;MIR4294;MSMB;NCOA4;OGDHL;PARG;PGBD3;PPYR1;PTPN20A;PTPN20B;RBP3;SLC18A3;SYT15;TIMM23;WDFY4;ZNF488","MAPK8","ERCC6;MAPK8","FAM21A","ARHGAP22","OGDHL","GDF10;MAPK8;NCOA4;OGDHL;SLC18A3;SYT15;TIMM23;ZNF488","MAPK8;NCOA4;OGDHL","AGAP4;AGAP7;AGAP8;AGAP9;ANTXRL;ANXA8;ANXA8L1;ANXA8L2;C10orf128;DRGX;FAM21A;FAM21B;FRMPD2;GDF2;LRRC18;MSMB;PPYR1;PTPN20A;PTPN20B;RBP3;WDFY4","ANXA8L1;C10orf128;DRGX;GDF10;MAPK8;NCOA4;OGDHL;PTPN20A;PTPN20B;RBP3;SLC18A3;TIMM23","ANXA8L1;DRGX;GDF10;MAPK8;NCOA4;PTPN20A;PTPN20B","DRGX;GDF10;MAPK8","CHAT;ERCC6;GDF10;MAPK8;PPYR1;RBP3;SLC18A3;ZNF488","CHAT;MAPK8;SLC18A3;ZNF488","ARHGAP22;CHAT;GDF10;GDF2;MAPK8;ZNF488","FAM21A","ARHGAP22;CHAT;ERCC6;FAM21A;GDF10;MAPK8;NCOA4;OGDHL;SLC18A3;TIMM23","ARHGAP22;CHAT;ERCC6;FAM21A;GDF10;GDF2;MAPK8;NCOA4;OGDHL;SLC18A3;TIMM23;ZNF488","-"]
["14393_5020","european",10,74801551,75278951,"DEL",477401,"AGAP5;ANXA7;BMS1P4;CAMK2G;CHCHD1;FUT11;KIAA0913;MYOZ1;NDST2;PPP3CB;SEC24C;SYNPO2L;USP54;ZMYND17","CAMK2G","CAMK2G;PPP3CB","-","SEC24C;USP54","ANXA7;CAMK2G;PPP3CB;SEC24C","ANXA7;CAMK2G;CHCHD1;FUT11;NDST2;PPP3CB;SEC24C;USP54","ANXA7;CAMK2G;CHCHD1;PPP3CB;SEC24C","AGAP5;MYOZ1;SYNPO2L","CAMK2G;MYOZ1;NDST2;PPP3CB;SEC24C;SYNPO2L;USP54","CAMK2G;NDST2;PPP3CB","NDST2;PPP3CB","CAMK2G;PPP3CB","ANXA7;CAMK2G;MYOZ1;PPP3CB","ANXA7;MYOZ1;PPP3CB","PPP3CB;SEC24C","ANXA7;CAMK2G;NDST2;PPP3CB;SEC24C;USP54","ANXA7;CAMK2G;MYOZ1;NDST2;PPP3CB;SEC24C;USP54","-"]
["6325_3","european",11,70077507,70506315,"DEL",428809,"MIR3664;SHANK2","SHANK2","SHANK2","SHANK2","-","SHANK2","SHANK2","-","-","SHANK2","-","-","SHANK2","SHANK2","-","SHANK2","SHANK2","SHANK2","SHANK2"]
["6319_3","european",11,70119917,70187872,"DEL",67956,"SHANK2","SHANK2","SHANK2","SHANK2","-","SHANK2","SHANK2","-","-","SHANK2","-","-","SHANK2","SHANK2","-","SHANK2","SHANK2","SHANK2","SHANK2"]
["5237_3","european",11,70154458,70220632,"DEL",66175,"SHANK2","SHANK2","SHANK2","SHANK2","-","SHANK2","SHANK2","-","-","SHANK2","-","-","SHANK2","SHANK2","-","SHANK2","SHANK2","SHANK2","SHANK2"]
["6240_4","european",11,126633939,132060374,"DEL",5426436,"ADAMTS15;ADAMTS8;APLP2;ARHGAP32;BARX2;C11orf45;ETS1;FLI1;KCNJ1;KCNJ5;NCRNA00167;NFRKB;NTM;OPCML;PRDM10;SNX19;ST14;TMEM45B;TP53AIP1;ZBTB44","ETS1","ARHGAP32;ETS1","ARHGAP32","APLP2;PRDM10","OPCML","ADAMTS8;APLP2;ARHGAP32;NTM;OPCML;SNX19;ZBTB44","APLP2;ARHGAP32;NTM;OPCML","C11orf45;KCNJ1;ST14;TMEM45B;TP53AIP1","ADAMTS15;ADAMTS8;APLP2;BARX2;C11orf45;ETS1;FLI1;NFRKB;OPCML;PRDM10;ST14","ETS1;FLI1;OPCML;ST14","ETS1;FLI1","APLP2;ARHGAP32;ETS1;KCNJ1;KCNJ5;NTM;OPCML","KCNJ1;KCNJ5;NTM;OPCML","ADAMTS8;APLP2;ETS1","ARHGAP32","APLP2;ARHGAP32;ETS1;NTM;OPCML;PRDM10","ADAMTS8;APLP2;ARHGAP32;ETS1;KCNJ1;NTM;OPCML;PRDM10","-"]
["6053_3","european",12,54218922,58779615,"DUP",4560694,"AGAP2;ANKRD52;APOF;ARHGAP9;ARHGEF25;ATP5B;AVIL;B4GALNT1;BAZ2A;BLOC1S1;BLOC1S1-RDH5;CD63;CDK2;CDK4;CNPY2;COQ10A;CS;CTDSP2;CYP27B1;DCTN2;DDIT3;DGKA;DNAJC14;DTX3;ERBB3;ESYT1;GDF11;GLI1;GLS2;GPR182;HSD17B6;IKZF4;IL23A;INHBC;INHBE;ITGA7;KIF5A;LOC100130776;LOC100506844;LOC440104;LRIG3;LRP1;MARCH9;MARS;MBD6;METTL1;METTL21B;METTL7B;MIP;MIR1228;MIR26A2;MMP19;MYL6;MYL6B;MYO1A;NAB2;NACA;NDUFA4L2;NXPH4;OBFC2B;OR10P1;OR6C4;ORMDL2;OS9;PA2G4;PAN2;PIP4K2C;PMEL;PRIM1;PTGES3;R3HDM2;RAB5B;RBMS2;RDH16;RDH5;RNF41;RPL41;RPS26;SARNP;SDR9C7;SHMT2;SLC16A7;SLC26A10;SLC39A5;SMARCC2;SNORD59A;SNORD59B;SPRYD4;STAC3;STAT2;STAT6;SUOX;TAC3;TIMELESS;TMEM194A;TSFM;TSPAN31;WIBG;XRCC6BP1;ZBTB39;ZC3H10","CDK4","CDK2;CDK4","AGAP2;ANKRD52;ATP5B;BAZ2A;KIF5A;LRP1;R3HDM2;SMARCC2","ESYT1;LRIG3;PAN2;TIMELESS","AGAP2;ATP5B;CS;DCTN2;KIF5A;LRP1;MARS;MYL6;MYL6B;RAB5B;SHMT2","AGAP2;ANKRD52;ARHGEF25;ATP5B;B4GALNT1;BAZ2A;BLOC1S1;CD63;CDK2;CDK4;COQ10A;CS;CTDSP2;DCTN2;DDIT3;DNAJC14;DTX3;ERBB3;ESYT1;GDF11;GLS2;HSD17B6;ITGA7;KIF5A;LRP1;MARCH9;MARS;MBD6;METTL7B;MYL6;MYL6B;NAB2;NACA;NDUFA4L2;NXPH4;ORMDL2;OS9;PA2G4;PAN2;PIP4K2C;PRIM1;PTGES3;R3HDM2;RAB5B;RNF41;RPL41;SARNP;SHMT2;SLC26A10;SMARCC2;SPRYD4;STAT2;SUOX;TAC3;TIMELESS;TSFM;TSPAN31;WIBG;ZC3H10","AGAP2;ARHGEF25;ATP5B;B4GALNT1;BLOC1S1;CD63;CDK2;CDK4;CS;CTDSP2;DCTN2;DDIT3;DTX3;KIF5A;LRP1;MARCH9;MARS;MYL6;MYL6B;NAB2;NACA;NDUFA4L2;NXPH4;OS9;PA2G4;PIP4K2C;PTGES3;R3HDM2;RAB5B;RNF41;RPL41;SARNP;SHMT2;SMARCC2","APOF;CNPY2;CYP27B1;GPR182;IL23A;INHBC;METTL21B;MIP;MMP19;MYO1A;OR10P1;OR6C4;PMEL;RBMS2;RDH16;RPS26;SDR9C7;SLC39A5;STAC3","ANKRD52;APOF;ATP5B;CD63;CDK2;CDK4;CNPY2;COQ10A;CS;CTDSP2;DCTN2;DDIT3;DGKA;DNAJC14;DTX3;ERBB3;GDF11;GLI1;GLS2;IKZF4;IL23A;ITGA7;KIF5A;LRIG3;LRP1;MARCH9;MARS;MBD6;METTL1;MIP;MMP19;NAB2;NDUFA4L2;OR10P1;ORMDL2;PA2G4;PAN2;PRIM1;PTGES3;R3HDM2;RAB5B;RDH5;RNF41;RPL41;SHMT2;SLC26A10;SMARCC2;STAT2;STAT6;TIMELESS;TSFM;TSPAN31;ZBTB39;ZC3H10","ANKRD52;ATP5B;CD63;CDK2;CDK4;CNPY2;CS;CTDSP2;DCTN2;DNAJC14;ERBB3;GDF11;GLI1;GLS2;IKZF4;KIF5A;LRP1;MARS;MMP19;NAB2;NDUFA4L2;PA2G4;PAN2;PRIM1;PTGES3;RAB5B;RDH5;RNF41;RPL41;SMARCC2;STAT2;STAT6;ZC3H10","ANKRD52;ATP5B;CDK2;CDK4;CS;DCTN2;ERBB3;GDF11;GLI1;GLS2;IKZF4;LRP1;MARS;NAB2;PA2G4;PAN2;PRIM1;PTGES3;RAB5B;RNF41;SMARCC2;STAT6","AGAP2;AVIL;DCTN2;ERBB3;GDF11;GLS2;KIF5A;LRP1;MIP;MYL6;MYO1A;NAB2;RDH5;SMARCC2","AGAP2;AVIL;CDK4;ERBB3;GDF11;GLS2;IL23A;ITGA7;KIF5A;MYL6;MYO1A","ATP5B;AVIL;CDK2;CDK4;CYP27B1;DCTN2;DDIT3;ERBB3;GDF11;GLI1;IL23A;INHBC;INHBE;ITGA7;LRP1;MMP19;NAB2;PA2G4;PRIM1;SHMT2;STAT6;TIMELESS;TSPAN31","AGAP2;ANKRD52;ATP5B;BAZ2A;CS;DCTN2;ERBB3;KIF5A;LRP1;MARS;R3HDM2;RAB5B;SMARCC2","AGAP2;ANKRD52;ATP5B;B4GALNT1;BAZ2A;CD63;CDK2;CDK4;CNPY2;CS;CTDSP2;DCTN2;ERBB3;ESYT1;GDF11;GLI1;GLS2;IKZF4;ITGA7;KIF5A;LRIG3;LRP1;MARS;MYL6;MYL6B;NAB2;NDUFA4L2;PA2G4;PAN2;PTGES3;R3HDM2;RAB5B;RDH5;RNF41;RPL41;SHMT2;SMARCC2;SUOX;TIMELESS","AGAP2;ANKRD52;ATP5B;AVIL;B4GALNT1;BAZ2A;CD63;CDK2;CDK4;CNPY2;CS;CTDSP2;CYP27B1;DCTN2;DDIT3;ERBB3;ESYT1;GDF11;GLI1;GLS2;IKZF4;IL23A;INHBC;INHBE;ITGA7;KIF5A;LRIG3;LRP1;MARS;MMP19;MYL6;MYL6B;NAB2;NDUFA4L2;PA2G4;PAN2;PRIM1;PTGES3;R3HDM2;RAB5B;RDH5;RNF41;RPL41;SHMT2;SMARCC2;STAT6;SUOX;TIMELESS;TSPAN31","-"]
["5272_3","other",12,98445422,98540678,"DEL",95257,"-","ANKS1B","ANKS1B","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-"]
["1050_3","european",14,20279711,20345174,"DUP",65464,"EDDM3A;EDDM3B;RNASE1;RNASE6","RNASE6","RNASE1;RNASE6","-","-","-","RNASE1","RNASE1","EDDM3A;EDDM3B","RNASE6","RNASE6","-","-","-","-","-","-","-","-"]
["8638_201","european",14,35203374,35369853,"DEL",166480,"BRMS1L;RALGAPA1","BRMS1L","BRMS1L;RALGAPA1","RALGAPA1","-","-","BRMS1L","-","-","BRMS1L","-","-","-","-","BRMS1L","RALGAPA1","RALGAPA1","BRMS1L;RALGAPA1","-"]
["4272_1","european",14,63824114,65347410,"DEL",1523297,"AKAP5;C14orf50;CHURC1;CHURC1-FNTB;ESR2;FNTB;FUT8;GPX2;HSPA2;LOC645431;MAX;MTHFD1;PLEKHG3;RAB15;SPTB;TEX21P;ZBTB1;ZBTB25","MAX","ESR2;MAX","SPTB","MTHFD1","HSPA2;MTHFD1;RAB15;SPTB","AKAP5;CHURC1-FNTB;FUT8;HSPA2;MAX;MTHFD1;PLEKHG3;RAB15;SPTB;ZBTB1","AKAP5;FUT8;HSPA2;MAX;RAB15;SPTB","CHURC1;ESR2;FNTB;GPX2","ESR2;FNTB;GPX2;HSPA2;MAX;MTHFD1;SPTB;ZBTB1","HSPA2;MTHFD1;ZBTB1","HSPA2;MTHFD1","AKAP5;ESR2;MAX;SPTB","AKAP5;ESR2;FUT8;SPTB","ESR2;FNTB;FUT8;HSPA2;MAX","HSPA2;MTHFD1;SPTB","AKAP5;HSPA2;MTHFD1;RAB15;SPTB","AKAP5;ESR2;FNTB;FUT8;HSPA2;MAX;MTHFD1;RAB15;SPTB","-"]
["17009_1","european",14,78575296,78596793,"DEL",21498,"-","NRXN3","NRXN3","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-","-"]
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["17035_1","european",15,20274130,26120360,"DUP",5846231,"ATP10A;C15orf2;CYFIP1;GABRA5;GABRB3;GABRG3;GOLGA6L1;GOLGA8E;GOLGA8IP;HBII-52-27;HBII-52-28;HBII-52-45;HBII-52-46;HERC2;HERC2P2;HERC2P7;IPW;MAGEL2;MKRN3;NDN;NIPA1;NIPA2;OCA2;PAR-SN;PAR1;PAR4;PAR5;PWRN1;PWRN2;SNORD107;SNORD108;SNORD109A;SNORD109B;SNORD115-1;SNORD115-10;SNORD115-11;SNORD115-12;SNORD115-13;SNORD115-14;SNORD115-15;SNORD115-16;SNORD115-17;SNORD115-18;SNORD115-19;SNORD115-2;SNORD115-20;SNORD115-21;SNORD115-22;SNORD115-23;SNORD115-24;SNORD115-25;SNORD115-26;SNORD115-29;SNORD115-3;SNORD115-30;SNORD115-31;SNORD115-32;SNORD115-33;SNORD115-34;SNORD115-35;SNORD115-36;SNORD115-37;SNORD115-38;SNORD115-39;SNORD115-4;SNORD115-40;SNORD115-41;SNORD115-42;SNORD115-43;SNORD115-44;SNORD115-48;SNORD115-5;SNORD115-6;SNORD115-7;SNORD115-8;SNORD115-9;SNORD116-1;SNORD116-10;SNORD116-11;SNORD116-12;SNORD116-13;SNORD116-14;SNORD116-15;SNORD116-16;SNORD116-17;SNORD116-18;SNORD116-19;SNORD116-2;SNORD116-20;SNORD116-21;SNORD116-22;SNORD116-23;SNORD116-24;SNORD116-25;SNORD116-26;SNORD116-27;SNORD116-28;SNORD116-29;SNORD116-3;SNORD116-4;SNORD116-5;SNORD116-6;SNORD116-7;SNORD116-8;SNORD116-9;SNORD64;SNRPN;SNURF;TUBGCP5;UBE3A;WHAMML1","UBE3A","SNRPN;UBE3A","HERC2","HERC2","CYFIP1","CYFIP1;GABRA5;GABRB3;HERC2;MKRN3;NDN;NIPA1;NIPA2;OCA2;SNRPN;SNURF;UBE3A","GABRA5;GABRB3;NDN;NIPA1;NIPA2;SNRPN;SNURF;UBE3A","MAGEL2","CYFIP1;GABRA5;GABRB3;HERC2;NDN;NIPA1;NIPA2;SNRPN;UBE3A","GABRB3;SNRPN;UBE3A","GABRB3;SNRPN","CYFIP1;GABRA5;GABRB3;GABRG3;NDN;UBE3A","ATP10A;CYFIP1;GABRA5;GABRB3;GABRG3;NDN","ATP10A;CYFIP1;NDN;TUBGCP5;UBE3A","HERC2","CYFIP1;GABRA5;GABRB3;HERC2;MAGEL2;NDN;OCA2;SNRPN;UBE3A","ATP10A;CYFIP1;GABRA5;GABRB3;HERC2;MAGEL2;NDN;OCA2;SNRPN;TUBGCP5;UBE3A","UBE3A"]
["13050_593","european",15,21190624,26203954,"DUP",5013331,"ATP10A;C15orf2;GABRA5;GABRB3;GABRG3;HBII-52-27;HBII-52-28;HBII-52-45;HBII-52-46;HERC2;IPW;MAGEL2;MKRN3;NDN;OCA2;PAR-SN;PAR1;PAR4;PAR5;PWRN1;PWRN2;SNORD107;SNORD108;SNORD109A;SNORD109B;SNORD115-1;SNORD115-10;SNORD115-11;SNORD115-12;SNORD115-13;SNORD115-14;SNORD115-15;SNORD115-16;SNORD115-17;SNORD115-18;SNORD115-19;SNORD115-2;SNORD115-20;SNORD115-21;SNORD115-22;SNORD115-23;SNORD115-24;SNORD115-25;SNORD115-26;SNORD115-29;SNORD115-3;SNORD115-30;SNORD115-31;SNORD115-32;SNORD115-33;SNORD115-34;SNORD115-35;SNORD115-36;SNORD115-37;SNORD115-38;SNORD115-39;SNORD115-4;SNORD115-40;SNORD115-41;SNORD115-42;SNORD115-43;SNORD115-44;SNORD115-48;SNORD115-5;SNORD115-6;SNORD115-7;SNORD115-8;SNORD115-9;SNORD116-1;SNORD116-10;SNORD116-11;SNORD116-12;SNORD116-13;SNORD116-14;SNORD116-15;SNORD116-16;SNORD116-17;SNORD116-18;SNORD116-19;SNORD116-2;SNORD116-20;SNORD116-21;SNORD116-22;SNORD116-23;SNORD116-24;SNORD116-25;SNORD116-26;SNORD116-27;SNORD116-28;SNORD116-29;SNORD116-3;SNORD116-4;SNORD116-5;SNORD116-6;SNORD116-7;SNORD116-8;SNORD116-9;SNORD64;SNRPN;SNURF;UBE3A","UBE3A","SNRPN;UBE3A","HERC2","HERC2","-","GABRA5;GABRB3;HERC2;MKRN3;NDN;OCA2;SNRPN;SNURF;UBE3A","GABRA5;GABRB3;NDN;SNRPN;SNURF;UBE3A","MAGEL2","GABRA5;GABRB3;HERC2;NDN;SNRPN;UBE3A","GABRB3;SNRPN;UBE3A","GABRB3;SNRPN","GABRA5;GABRB3;GABRG3;NDN;UBE3A","ATP10A;GABRA5;GABRB3;GABRG3;NDN","ATP10A;NDN;UBE3A","HERC2","GABRA5;GABRB3;HERC2;MAGEL2;NDN;OCA2;SNRPN;UBE3A","ATP10A;GABRA5;GABRB3;HERC2;MAGEL2;NDN;OCA2;SNRPN;UBE3A","UBE3A"]
["16040_1571029001","european",15,28450423,30303265,"DEL",1852843,"ARHGAP11B;CHRFAM7A;CHRNA7;FAM7A1;FAM7A2;FAN1;KLF13;LOC100288637;MIR211;MTMR10;OTUD7A;TRPM1","CHRNA7","CHRNA7;KLF13","-","OTUD7A","-","FAN1;KLF13;MTMR10","KLF13","ARHGAP11B;CHRFAM7A;CHRNA7;TRPM1","CHRNA7;KLF13;OTUD7A","CHRNA7;KLF13","KLF13","CHRNA7;TRPM1","CHRNA7","CHRNA7;KLF13","-","CHRNA7;KLF13;OTUD7A","CHRNA7;KLF13;OTUD7A","-"]
["6101_4","other",15,74735339,74929817,"DEL",194479,"SCAPER","SCAPER","SCAPER","-","-","-","SCAPER","-","-","-","-","-","-","-","-","-","-","-","-"]
["8695_201","european",15,81728085,82623936,"DEL",895852,"ADAMTSL3;BNC1;LOC648809;SH3GL3","SH3GL3","BNC1;SH3GL3","-","-","SH3GL3","SH3GL3","SH3GL3","BNC1","ADAMTSL3;BNC1","-","-","SH3GL3","-","BNC1","-","SH3GL3","BNC1;SH3GL3","-"]
["14181_2940","european",15,82906265,82985247,"DUP",78983,"LOC100506874;SCAND2;UBE2Q2P1;ZSCAN2","ZSCAN2","SCAND2;ZSCAN2","-","-","-","ZSCAN2","-","-","ZSCAN2","ZSCAN2","ZSCAN2","-","-","-","-","-","-","-"]
["14070_1230","european",15,91200007,91283004,"DEL",82998,"CHD2;LOC100507217;MIR3175","CHD2","CHD2","-","-","-","CHD2","-","-","CHD2","CHD2","-","-","-","-","-","CHD2","CHD2","-"]
["2204_1","european",16,29466569,30147029,"DEL",680461,"ALDOA;ASPHD1;BOLA2;BOLA2B;C16orf53;C16orf54;C16orf92;CDIPT;CORO1A;DOC2A;FAM57B;GDPD3;HIRIP3;INO80E;KCTD13;LOC100271831;LOC388242;LOC440354;LOC440356;LOC606724;LOC613037;LOC613038;MAPK3;MAZ;MVP;PPP4C;PRRT2;QPRT;SEZ6L2;SLC7A5P1;SLX1A;SLX1A-SULT1A3;SLX1B;SLX1B-SULT1A4;SPN;SULT1A3;SULT1A4;TAOK2;TBX6;TMEM219;YPEL3;ZG16","MAPK3","MAPK3;TAOK2","ALDOA;MAZ;SEZ6L2;TAOK2","TAOK2","ALDOA;CORO1A;MAPK3;MVP;TAOK2","ALDOA;ASPHD1;CDIPT;CORO1A;DOC2A;FAM57B;HIRIP3;INO80E;KCTD13;MAPK3;MAZ;MVP;PPP4C;PRRT2;QPRT;SEZ6L2;TAOK2;TMEM219;YPEL3","ALDOA;ASPHD1;CDIPT;CORO1A;DOC2A;FAM57B;HIRIP3;INO80E;KCTD13;MAPK3;MAZ;PPP4C;PRRT2;SEZ6L2;TAOK2;TMEM219;YPEL3","C16orf54;C16orf92;SLX1A;SLX1B;SPN;SULT1A3;SULT1A4;TBX6;ZG16","ALDOA;CORO1A;DOC2A;FAM57B;HIRIP3;KCTD13;MAPK3;MAZ;PPP4C;PRRT2;SEZ6L2;SPN;SULT1A3;SULT1A4;TAOK2;YPEL3","CORO1A;MAPK3;PPP4C;SEZ6L2;SULT1A3;SULT1A4;TAOK2","CORO1A;MAPK3;PPP4C;SULT1A3;SULT1A4;TAOK2","DOC2A;MAPK3;TAOK2","ALDOA;CORO1A;MAPK3;SPN;TAOK2","ALDOA;CORO1A;KCTD13;SPN;TAOK2;TBX6","ALDOA;CORO1A;MAPK3;MAZ;SEZ6L2;TAOK2","ALDOA;CDIPT;CORO1A;DOC2A;MAPK3;MAZ;MVP;PPP4C;SEZ6L2;TAOK2","ALDOA;CDIPT;CORO1A;DOC2A;KCTD13;MAPK3;MAZ;MVP;PPP4C;SEZ6L2;SPN;TAOK2;TBX6","-"]
["20089_1391001","european",16,29502984,30107306,"DEL",604323,"ALDOA;ASPHD1;C16orf53;C16orf54;C16orf92;CDIPT;CORO1A;DOC2A;FAM57B;GDPD3;HIRIP3;INO80E;KCTD13;LOC100271831;LOC440356;MAPK3;MAZ;MVP;PPP4C;PRRT2;QPRT;SEZ6L2;SLC7A5P1;SPN;TAOK2;TBX6;TMEM219;YPEL3;ZG16","MAPK3","MAPK3;TAOK2","ALDOA;MAZ;SEZ6L2;TAOK2","TAOK2","ALDOA;CORO1A;MAPK3;MVP;TAOK2","ALDOA;ASPHD1;CDIPT;CORO1A;DOC2A;FAM57B;HIRIP3;INO80E;KCTD13;MAPK3;MAZ;MVP;PPP4C;PRRT2;QPRT;SEZ6L2;TAOK2;TMEM219;YPEL3","ALDOA;ASPHD1;CDIPT;CORO1A;DOC2A;FAM57B;HIRIP3;INO80E;KCTD13;MAPK3;MAZ;PPP4C;PRRT2;SEZ6L2;TAOK2;TMEM219;YPEL3","C16orf54;C16orf92;SPN;TBX6;ZG16","ALDOA;CORO1A;DOC2A;FAM57B;HIRIP3;KCTD13;MAPK3;MAZ;PPP4C;PRRT2;SEZ6L2;SPN;TAOK2;YPEL3","CORO1A;MAPK3;PPP4C;SEZ6L2;TAOK2","CORO1A;MAPK3;PPP4C;TAOK2","DOC2A;MAPK3;TAOK2","ALDOA;CORO1A;MAPK3;SPN;TAOK2","ALDOA;CORO1A;KCTD13;SPN;TAOK2;TBX6","ALDOA;CORO1A;MAPK3;MAZ;SEZ6L2;TAOK2","ALDOA;CDIPT;CORO1A;DOC2A;MAPK3;MAZ;MVP;PPP4C;SEZ6L2;TAOK2","ALDOA;CDIPT;CORO1A;DOC2A;KCTD13;MAPK3;MAZ;MVP;PPP4C;SEZ6L2;SPN;TAOK2;TBX6","-"]
["5068_3","european",16,29502984,30127026,"DEL",624043,"ALDOA;ASPHD1;BOLA2;BOLA2B;C16orf53;C16orf54;C16orf92;CDIPT;CORO1A;DOC2A;FAM57B;GDPD3;HIRIP3;INO80E;KCTD13;LOC100271831;LOC388242;LOC440356;LOC606724;LOC613038;MAPK3;MAZ;MVP;PPP4C;PRRT2;QPRT;SEZ6L2;SLC7A5P1;SLX1A;SLX1A-SULT1A3;SLX1B;SLX1B-SULT1A4;SPN;SULT1A3;SULT1A4;TAOK2;TBX6;TMEM219;YPEL3;ZG16","MAPK3","MAPK3;TAOK2","ALDOA;MAZ;SEZ6L2;TAOK2","TAOK2","ALDOA;CORO1A;MAPK3;MVP;TAOK2","ALDOA;ASPHD1;CDIPT;CORO1A;DOC2A;FAM57B;HIRIP3;INO80E;KCTD13;MAPK3;MAZ;MVP;PPP4C;PRRT2;QPRT;SEZ6L2;TAOK2;TMEM219;YPEL3","ALDOA;ASPHD1;CDIPT;CORO1A;DOC2A;FAM57B;HIRIP3;INO80E;KCTD13;MAPK3;MAZ;PPP4C;PRRT2;SEZ6L2;TAOK2;TMEM219;YPEL3","C16orf54;C16orf92;SLX1A;SLX1B;SPN;SULT1A3;SULT1A4;TBX6;ZG16","ALDOA;CORO1A;DOC2A;FAM57B;HIRIP3;KCTD13;MAPK3;MAZ;PPP4C;PRRT2;SEZ6L2;SPN;SULT1A3;SULT1A4;TAOK2;YPEL3","CORO1A;MAPK3;PPP4C;SEZ6L2;SULT1A3;SULT1A4;TAOK2","CORO1A;MAPK3;PPP4C;SULT1A3;SULT1A4;TAOK2","DOC2A;MAPK3;TAOK2","ALDOA;CORO1A;MAPK3;SPN;TAOK2","ALDOA;CORO1A;KCTD13;SPN;TAOK2;TBX6","ALDOA;CORO1A;MAPK3;MAZ;SEZ6L2;TAOK2","ALDOA;CDIPT;CORO1A;DOC2A;MAPK3;MAZ;MVP;PPP4C;SEZ6L2;TAOK2","ALDOA;CDIPT;CORO1A;DOC2A;KCTD13;MAPK3;MAZ;MVP;PPP4C;SEZ6L2;SPN;TAOK2;TBX6","-"]
["5262_4","european",16,29502984,30210849,"DUP",707866,"ALDOA;ASPHD1;BOLA2;BOLA2B;C16orf53;C16orf54;C16orf92;CDIPT;CORO1A;DOC2A;FAM57B;GDPD3;HIRIP3;INO80E;KCTD13;LOC100271831;LOC388242;LOC440354;LOC440356;LOC595101;LOC606724;LOC613037;LOC613038;MAPK3;MAZ;MVP;PPP4C;PRRT2;QPRT;SEZ6L2;SLC7A5P1;SLX1A;SLX1A-SULT1A3;SLX1B;SLX1B-SULT1A4;SPN;SULT1A3;SULT1A4;TAOK2;TBX6;TMEM219;YPEL3;ZG16","MAPK3","MAPK3;TAOK2","ALDOA;MAZ;SEZ6L2;TAOK2","TAOK2","ALDOA;CORO1A;MAPK3;MVP;TAOK2","ALDOA;ASPHD1;CDIPT;CORO1A;DOC2A;FAM57B;HIRIP3;INO80E;KCTD13;MAPK3;MAZ;MVP;PPP4C;PRRT2;QPRT;SEZ6L2;TAOK2;TMEM219;YPEL3","ALDOA;ASPHD1;CDIPT;CORO1A;DOC2A;FAM57B;HIRIP3;INO80E;KCTD13;MAPK3;MAZ;PPP4C;PRRT2;SEZ6L2;TAOK2;TMEM219;YPEL3","C16orf54;C16orf92;SLX1A;SLX1B;SPN;SULT1A3;SULT1A4;TBX6;ZG16","ALDOA;CORO1A;DOC2A;FAM57B;HIRIP3;KCTD13;MAPK3;MAZ;PPP4C;PRRT2;SEZ6L2;SPN;SULT1A3;SULT1A4;TAOK2;YPEL3","CORO1A;MAPK3;PPP4C;SEZ6L2;SULT1A3;SULT1A4;TAOK2","CORO1A;MAPK3;PPP4C;SULT1A3;SULT1A4;TAOK2","DOC2A;MAPK3;TAOK2","ALDOA;CORO1A;MAPK3;SPN;TAOK2","ALDOA;CORO1A;KCTD13;SPN;TAOK2;TBX6","ALDOA;CORO1A;MAPK3;MAZ;SEZ6L2;TAOK2","ALDOA;CDIPT;CORO1A;DOC2A;MAPK3;MAZ;MVP;PPP4C;SEZ6L2;TAOK2","ALDOA;CDIPT;CORO1A;DOC2A;KCTD13;MAPK3;MAZ;MVP;PPP4C;SEZ6L2;SPN;TAOK2;TBX6","-"]
["4030_1","european",16,29554843,30107306,"DUP",552464,"ALDOA;ASPHD1;C16orf53;C16orf54;C16orf92;CDIPT;CORO1A;DOC2A;FAM57B;GDPD3;HIRIP3;INO80E;KCTD13;LOC100271831;LOC440356;MAPK3;MAZ;MVP;PPP4C;PRRT2;QPRT;SEZ6L2;SPN;TAOK2;TBX6;TMEM219;YPEL3;ZG16","MAPK3","MAPK3;TAOK2","ALDOA;MAZ;SEZ6L2;TAOK2","TAOK2","ALDOA;CORO1A;MAPK3;MVP;TAOK2","ALDOA;ASPHD1;CDIPT;CORO1A;DOC2A;FAM57B;HIRIP3;INO80E;KCTD13;MAPK3;MAZ;MVP;PPP4C;PRRT2;QPRT;SEZ6L2;TAOK2;TMEM219;YPEL3","ALDOA;ASPHD1;CDIPT;CORO1A;DOC2A;FAM57B;HIRIP3;INO80E;KCTD13;MAPK3;MAZ;PPP4C;PRRT2;SEZ6L2;TAOK2;TMEM219;YPEL3","C16orf54;C16orf92;SPN;TBX6;ZG16","ALDOA;CORO1A;DOC2A;FAM57B;HIRIP3;KCTD13;MAPK3;MAZ;PPP4C;PRRT2;SEZ6L2;SPN;TAOK2;YPEL3","CORO1A;MAPK3;PPP4C;SEZ6L2;TAOK2","CORO1A;MAPK3;PPP4C;TAOK2","DOC2A;MAPK3;TAOK2","ALDOA;CORO1A;MAPK3;SPN;TAOK2","ALDOA;CORO1A;KCTD13;SPN;TAOK2;TBX6","ALDOA;CORO1A;MAPK3;MAZ;SEZ6L2;TAOK2","ALDOA;CDIPT;CORO1A;DOC2A;MAPK3;MAZ;MVP;PPP4C;SEZ6L2;TAOK2","ALDOA;CDIPT;CORO1A;DOC2A;KCTD13;MAPK3;MAZ;MVP;PPP4C;SEZ6L2;SPN;TAOK2;TBX6","-"]
["5359_4","european",16,29554843,30195224,"DEL",640382,"ALDOA;ASPHD1;BOLA2;BOLA2B;C16orf53;C16orf54;C16orf92;CDIPT;CORO1A;DOC2A;FAM57B;GDPD3;HIRIP3;INO80E;KCTD13;LOC100271831;LOC388242;LOC440354;LOC440356;LOC595101;LOC606724;LOC613037;LOC613038;MAPK3;MAZ;MVP;PPP4C;PRRT2;QPRT;SEZ6L2;SLX1A;SLX1A-SULT1A3;SLX1B;SLX1B-SULT1A4;SPN;SULT1A3;SULT1A4;TAOK2;TBX6;TMEM219;YPEL3;ZG16","MAPK3","MAPK3;TAOK2","ALDOA;MAZ;SEZ6L2;TAOK2","TAOK2","ALDOA;CORO1A;MAPK3;MVP;TAOK2","ALDOA;ASPHD1;CDIPT;CORO1A;DOC2A;FAM57B;HIRIP3;INO80E;KCTD13;MAPK3;MAZ;MVP;PPP4C;PRRT2;QPRT;SEZ6L2;TAOK2;TMEM219;YPEL3","ALDOA;ASPHD1;CDIPT;CORO1A;DOC2A;FAM57B;HIRIP3;INO80E;KCTD13;MAPK3;MAZ;PPP4C;PRRT2;SEZ6L2;TAOK2;TMEM219;YPEL3","C16orf54;C16orf92;SLX1A;SLX1B;SPN;SULT1A3;SULT1A4;TBX6;ZG16","ALDOA;CORO1A;DOC2A;FAM57B;HIRIP3;KCTD13;MAPK3;MAZ;PPP4C;PRRT2;SEZ6L2;SPN;SULT1A3;SULT1A4;TAOK2;YPEL3","CORO1A;MAPK3;PPP4C;SEZ6L2;SULT1A3;SULT1A4;TAOK2","CORO1A;MAPK3;PPP4C;SULT1A3;SULT1A4;TAOK2","DOC2A;MAPK3;TAOK2","ALDOA;CORO1A;MAPK3;SPN;TAOK2","ALDOA;CORO1A;KCTD13;SPN;TAOK2;TBX6","ALDOA;CORO1A;MAPK3;MAZ;SEZ6L2;TAOK2","ALDOA;CDIPT;CORO1A;DOC2A;MAPK3;MAZ;MVP;PPP4C;SEZ6L2;TAOK2","ALDOA;CDIPT;CORO1A;DOC2A;KCTD13;MAPK3;MAZ;MVP;PPP4C;SEZ6L2;SPN;TAOK2;TBX6","-"]
["3439_3","european",17,17156307,18262979,"DEL",1106673,"ALKBH5;ATPAF2;C17orf39;DRG2;EVPLL;FLII;LLGL1;LRRC48;MED9;MIR33B;MYO15A;NT5M;PEMT;RAI1;RASD1;SHMT1;SMCR5;SMCR7;SMCR8;SREBF1;TOM1L2;TOP3A","-","SREBF1","LLGL1","FLII;TOP3A","FLII;LLGL1;TOM1L2","ALKBH5;ATPAF2;DRG2;FLII;LLGL1;MED9;NT5M;PEMT;RAI1;RASD1;SMCR7;SREBF1;TOM1L2;TOP3A","ALKBH5;LLGL1;PEMT;RAI1;RASD1;SREBF1;TOM1L2","MYO15A","ALKBH5;DRG2;FLII;LLGL1;MED9;MYO15A;RASD1;SHMT1;SMCR8;SREBF1;TOM1L2;TOP3A","SHMT1;TOP3A","SHMT1;TOP3A","MYO15A","MED9;SREBF1","MYO15A;PEMT;RAI1","FLII;LLGL1;TOM1L2","FLII;LLGL1;RAI1;RASD1;TOM1L2;TOP3A","FLII;LLGL1;MYO15A;PEMT;RAI1;RASD1;TOM1L2;TOP3A","-"]
["2211_1","european",17,17169258,20101517,"DEL",2932260,"AKAP10;ALDH3A1;ALDH3A2;ALKBH5;ATPAF2;B9D1;C17orf39;CCDC144B;DRG2;EPN2;EVPLL;FAM106A;FAM18B1;FAM83G;FBXW10;FLII;FOXO3B;GRAP;GRAPL;LGALS9C;LLGL1;LOC220594;LOC339240;LRRC48;MAPK7;MED9;MFAP4;MIR1180;MIR33B;MYO15A;NT5M;PEMT;PRPSAP2;RAI1;RASD1;RNF112;SHMT1;SLC47A1;SLC47A2;SLC5A10;SMCR5;SMCR7;SMCR8;SNORA59A;SNORA59B;SPECC1;SREBF1;TBC1D28;TOM1L2;TOP3A;TRIM16L;ULK2;ZNF286B","MAPK7","MAPK7;SREBF1","LLGL1;ULK2","FAM83G;FLII;MAPK7;TOP3A","ALDH3A2;FLII;LLGL1;SPECC1;TOM1L2","AKAP10;ALDH3A2;ALKBH5;ATPAF2;B9D1;DRG2;EPN2;FLII;LLGL1;MAPK7;MED9;MFAP4;NT5M;PEMT;PRPSAP2;RAI1;RASD1;RNF112;SMCR7;SPECC1;SREBF1;TOM1L2;TOP3A;TRIM16L;ULK2","ALDH3A2;ALKBH5;EPN2;LLGL1;MAPK7;PEMT;PRPSAP2;RAI1;RASD1;RNF112;SREBF1;TOM1L2;ULK2","ALDH3A1;FBXW10;GRAP;LGALS9C;LOC339240;MYO15A;SLC5A10;TBC1D28;ZNF286B","AKAP10;ALDH3A1;ALKBH5;DRG2;EPN2;FBXW10;FLII;GRAP;LLGL1;MAPK7;MED9;MFAP4;MYO15A;RASD1;SHMT1;SMCR8;SREBF1;TBC1D28;TOM1L2;TOP3A;ULK2","AKAP10;ALDH3A1;GRAP;MAPK7;SHMT1;TOP3A;ULK2","MAPK7;SHMT1;TOP3A","MAPK7;MYO15A;ULK2","B9D1;MED9;SREBF1;ULK2","ALDH3A1;B9D1;MAPK7;MYO15A;PEMT;RAI1","FLII;LLGL1;MAPK7;TOM1L2;ULK2","ALDH3A2;B9D1;FAM83G;FLII;LLGL1;MAPK7;RAI1;RASD1;SPECC1;TOM1L2;TOP3A;ULK2","ALDH3A1;ALDH3A2;B9D1;FAM83G;FLII;LLGL1;MAPK7;MYO15A;PEMT;RAI1;RASD1;SPECC1;TOM1L2;TOP3A;ULK2","-"]
["5056_4","european",17,34612208,34732327,"DUP",120120,"FBXL20;RPL19;STAC2","RPL19","RPL19;STAC2","-","-","-","RPL19;STAC2","RPL19;STAC2","-","FBXL20;RPL19;STAC2","FBXL20","FBXL20","-","-","-","-","-","-","-"]
["8463_202","european",17,52774693,52887687,"DEL",112995,"MSI2","MSI2","MSI2","-","-","-","MSI2","-","-","MSI2","-","-","-","-","-","-","-","-","-"]
["5444_3","european",17,76953064,77782267,"DUP",829204,"ACTG1;ANAPC11;ARHGDIA;ARL16;ASPSCR1;BAHCC1;C17orf70;C17orf90;CCDC137;CCDC57;DCXR;DUS1L;DYSFIP1;FASN;FSCN2;GPS1;HGS;LOC92659;LRRC45;MAFG;MIR3186;MRPL12;MYADML2;NOTUM;NPB;NPLOC4;P4HB;PCYT2;PDE6G;PYCR1;RAC3;RFNG;SIRT7;SLC16A3;SLC25A10;STRA13;THOC4;TSPAN10","ARHGDIA","ARHGDIA;RAC3","FASN","DUS1L;HGS","ARHGDIA;FASN;HGS","ACTG1;ANAPC11;ARHGDIA;ARL16;ASPSCR1;BAHCC1;C17orf70;CCDC137;DCXR;DUS1L;FASN;GPS1;HGS;LRRC45;MAFG;MYADML2;NPB;NPLOC4;P4HB;PCYT2;PYCR1;RAC3;RFNG;SIRT7;SLC16A3;STRA13","ACTG1;ANAPC11;ARHGDIA;ARL16;C17orf70;DCXR;FASN;GPS1;HGS;MAFG;NPB;P4HB;PCYT2;PYCR1;RAC3;STRA13","MRPL12;PDE6G;TSPAN10","ACTG1;ANAPC11;FASN;GPS1;HGS;LRRC45;MAFG;MRPL12;NOTUM;NPLOC4;P4HB;PCYT2;PDE6G;RAC3;SLC16A3;SLC25A10;STRA13","ACTG1;ANAPC11;FASN;HGS;MAFG;MRPL12;P4HB;RAC3","ACTG1;MRPL12;RAC3","ACTG1;ARHGDIA;FSCN2;PDE6G;RAC3;RFNG","ACTG1;ARHGDIA;RAC3","ACTG1;ANAPC11;ARHGDIA;HGS;MAFG;SLC16A3","ACTG1;FASN;HGS","ACTG1;ANAPC11;ARHGDIA;DUS1L;FASN;FSCN2;HGS;MAFG;MRPL12;NPB;P4HB;RAC3","ACTG1;ANAPC11;ARHGDIA;DUS1L;FASN;FSCN2;HGS;MAFG;MRPL12;NPB;P4HB;RAC3;SLC16A3","-"]
["5444_3","european",17,77785939,77849717,"DEL",63779,"CSNK1D;SLC16A3","CSNK1D","CSNK1D","-","-","CSNK1D","CSNK1D;SLC16A3","CSNK1D","-","CSNK1D;SLC16A3","CSNK1D","CSNK1D","-","-","CSNK1D;SLC16A3","CSNK1D","CSNK1D","CSNK1D;SLC16A3","-"]
["3477_3","european",18,30280260,30327512,"DEL",47253,"DTNA","DTNA","DTNA","DTNA","-","DTNA","DTNA","DTNA","-","DTNA","DTNA","DTNA","DTNA","-","-","DTNA","DTNA","DTNA","-"]
["14331_4450","european",18,72085223,73670156,"DEL",1584934,"GALR1;LOC284276;MBP;ZNF236;ZNF516","GALR1","GALR1;ZNF516","MBP","-","MBP","MBP","MBP","-","ZNF516","-","-","MBP","-","-","MBP","MBP","MBP","-"]
["6358_6","european",19,4548413,5287389,"DEL",738977,"ARRDC5;C19orf10;DPP9;FEM1A;KDM4B;MIR7-3;NCRNA00306;PLIN3;PTPRS;TICAM1;TNFAIP8L1;UHRF1","UHRF1","TICAM1;UHRF1","KDM4B;PTPRS","KDM4B;PTPRS","PTPRS","C19orf10;FEM1A;KDM4B;PLIN3;PTPRS;TICAM1;TNFAIP8L1;UHRF1","C19orf10;KDM4B;PLIN3;PTPRS","ARRDC5","DPP9;FEM1A;PTPRS;UHRF1","-","-","PTPRS","-","TICAM1","KDM4B;PTPRS","KDM4B;PTPRS;TICAM1;UHRF1","KDM4B;PTPRS;TICAM1;UHRF1","-"]
["5046_3","other",20,8607242,8637441,"DEL",30200,"PLCB1","PLCB1","PLCB1","PLCB1","PLCB1","PLCB1","PLCB1","PLCB1","-","PLCB1","PLCB1","-","PLCB1","PLCB1","PLCB1","PLCB1","PLCB1","PLCB1","-"]
["5335_3","european",20,14545734,14948785,"DEL",403052,"MACROD2;MACROD2-AS1","-","-","-","-","-","MACROD2","-","-","MACROD2","-","-","-","-","-","-","-","-","-"]
["20180_1704001","european",21,43018846,43444308,"DUP",425463,"CBS;NDUFV3;PDE9A;PKNOX1;U2AF1;WDR4","CBS","CBS;WDR4","-","-","-","CBS;NDUFV3;PDE9A;PKNOX1;U2AF1","CBS;NDUFV3;U2AF1","-","CBS;PDE9A;U2AF1;WDR4","CBS;PDE9A;WDR4","WDR4","CBS","-","PKNOX1","-","CBS;WDR4","CBS;PKNOX1;WDR4","-"]
["3183_7","european",22,17241748,19819918,"DEL",2578171,"AIFM3;ARVCF;BCRP2;C22orf25;C22orf29;C22orf39;CDC45;CLDN5;CLTCL1;COMT;CRKL;DGCR10;DGCR11;DGCR14;DGCR2;DGCR5;DGCR6;DGCR6L;DGCR8;DGCR9;FLJ39582;GNB1L;GP1BB;GSC2;HIRA;KLHL22;LOC150185;LOC150197;LOC400891;LZTR1;MED15;MGC16703;MIR1286;MIR1306;MIR185;MIR3618;MRPL40;P2RX6;P2RX6P;PI4KA;PI4KAP1;POM121L4P;PRODH;RANBP1;RIMBP3;RTN4R;SCARF2;SEPT5;SEPT5-GP1BB;SERPIND1;SLC25A1;SLC7A4;SNAP29;TBX1;THAP7;TMEM191A;TMEM191B;TRMT2A;TSSK2;TXNRD2;UFD1L;ZDHHC8;ZNF74","CRKL","CRKL;TSSK2","ARVCF;DGCR2;KLHL22;PI4KA;RTN4R;SEPT5","DGCR8;HIRA;PI4KA","AIFM3;CRKL;PI4KA;PRODH;SEPT5;SLC25A1","AIFM3;ARVCF;C22orf29;C22orf39;CLDN5;COMT;CRKL;DGCR14;DGCR2;DGCR6;DGCR6L;DGCR8;GNB1L;GP1BB;HIRA;KLHL22;LZTR1;MED15;MRPL40;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SERPIND1;SLC25A1;SLC7A4;SNAP29;THAP7;TRMT2A;TSSK2;TXNRD2;UFD1L;ZDHHC8;ZNF74","AIFM3;ARVCF;C22orf39;CLDN5;COMT;CRKL;DGCR2;DGCR6;DGCR6L;GP1BB;KLHL22;MRPL40;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SLC25A1;THAP7;UFD1L;ZDHHC8;ZNF74","GSC2;PI4KAP1;TBX1;TMEM191A;TMEM191B","ARVCF;CLDN5;CLTCL1;CRKL;DGCR14;DGCR2;DGCR8;HIRA;KLHL22;LZTR1;MED15;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SERPIND1;SLC25A1;SLC7A4;TBX1;THAP7;TSSK2;UFD1L;ZNF74","CRKL;HIRA;KLHL22;MED15;PRODH;RANBP1;SERPIND1;SLC7A4;UFD1L","CRKL;HIRA;MED15;PRODH;RANBP1;SERPIND1","CLTCL1;COMT;CRKL;DGCR14;P2RX6;PI4KA;RTN4R;SEPT5;TBX1","COMT;MED15;RTN4R;SERPIND1","CDC45;COMT;CRKL;HIRA;RANBP1;RTN4R;TBX1;TXNRD2","ARVCF;CRKL;DGCR2;HIRA;KLHL22;PI4KA;PRODH;RTN4R;SEPT5","AIFM3;ARVCF;CLDN5;COMT;CRKL;DGCR2;DGCR8;HIRA;KLHL22;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SLC25A1;TBX1;UFD1L;ZDHHC8","AIFM3;ARVCF;CDC45;CLDN5;COMT;CRKL;DGCR2;DGCR8;HIRA;KLHL22;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SLC25A1;TBX1;TXNRD2;UFD1L;ZDHHC8","-"]
["8627_201","european",22,17257787,19793730,"DUP",2535944,"AIFM3;ARVCF;BCRP2;C22orf25;C22orf29;C22orf39;CDC45;CLDN5;CLTCL1;COMT;CRKL;DGCR10;DGCR11;DGCR14;DGCR2;DGCR5;DGCR6;DGCR6L;DGCR8;DGCR9;FLJ39582;GNB1L;GP1BB;GSC2;HIRA;KLHL22;LOC150185;LOC150197;LOC400891;LZTR1;MED15;MGC16703;MIR1286;MIR1306;MIR185;MIR3618;MRPL40;P2RX6;P2RX6P;PI4KA;PI4KAP1;POM121L4P;PRODH;RANBP1;RIMBP3;RTN4R;SCARF2;SEPT5;SEPT5-GP1BB;SERPIND1;SLC25A1;SLC7A4;SNAP29;TBX1;THAP7;TMEM191A;TMEM191B;TRMT2A;TSSK2;TXNRD2;UFD1L;ZDHHC8;ZNF74","CRKL","CRKL;TSSK2","ARVCF;DGCR2;KLHL22;PI4KA;RTN4R;SEPT5","DGCR8;HIRA;PI4KA","AIFM3;CRKL;PI4KA;PRODH;SEPT5;SLC25A1","AIFM3;ARVCF;C22orf29;C22orf39;CLDN5;COMT;CRKL;DGCR14;DGCR2;DGCR6;DGCR6L;DGCR8;GNB1L;GP1BB;HIRA;KLHL22;LZTR1;MED15;MRPL40;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SERPIND1;SLC25A1;SLC7A4;SNAP29;THAP7;TRMT2A;TSSK2;TXNRD2;UFD1L;ZDHHC8;ZNF74","AIFM3;ARVCF;C22orf39;CLDN5;COMT;CRKL;DGCR2;DGCR6;DGCR6L;GP1BB;KLHL22;MRPL40;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SLC25A1;THAP7;UFD1L;ZDHHC8;ZNF74","GSC2;PI4KAP1;TBX1;TMEM191A;TMEM191B","ARVCF;CLDN5;CLTCL1;CRKL;DGCR14;DGCR2;DGCR8;HIRA;KLHL22;LZTR1;MED15;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SERPIND1;SLC25A1;SLC7A4;TBX1;THAP7;TSSK2;UFD1L;ZNF74","CRKL;HIRA;KLHL22;MED15;PRODH;RANBP1;SERPIND1;SLC7A4;UFD1L","CRKL;HIRA;MED15;PRODH;RANBP1;SERPIND1","CLTCL1;COMT;CRKL;DGCR14;P2RX6;PI4KA;RTN4R;SEPT5;TBX1","COMT;MED15;RTN4R;SERPIND1","CDC45;COMT;CRKL;HIRA;RANBP1;RTN4R;TBX1;TXNRD2","ARVCF;CRKL;DGCR2;HIRA;KLHL22;PI4KA;PRODH;RTN4R;SEPT5","AIFM3;ARVCF;CLDN5;COMT;CRKL;DGCR2;DGCR8;HIRA;KLHL22;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SLC25A1;TBX1;UFD1L;ZDHHC8","AIFM3;ARVCF;CDC45;CLDN5;COMT;CRKL;DGCR2;DGCR8;HIRA;KLHL22;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SLC25A1;TBX1;TXNRD2;UFD1L;ZDHHC8","-"]
["17015_1","european",22,17257787,19795780,"DEL",2537994,"AIFM3;ARVCF;BCRP2;C22orf25;C22orf29;C22orf39;CDC45;CLDN5;CLTCL1;COMT;CRKL;DGCR10;DGCR11;DGCR14;DGCR2;DGCR5;DGCR6;DGCR6L;DGCR8;DGCR9;FLJ39582;GNB1L;GP1BB;GSC2;HIRA;KLHL22;LOC150185;LOC150197;LOC400891;LZTR1;MED15;MGC16703;MIR1286;MIR1306;MIR185;MIR3618;MRPL40;P2RX6;P2RX6P;PI4KA;PI4KAP1;POM121L4P;PRODH;RANBP1;RIMBP3;RTN4R;SCARF2;SEPT5;SEPT5-GP1BB;SERPIND1;SLC25A1;SLC7A4;SNAP29;TBX1;THAP7;TMEM191A;TMEM191B;TRMT2A;TSSK2;TXNRD2;UFD1L;ZDHHC8;ZNF74","CRKL","CRKL;TSSK2","ARVCF;DGCR2;KLHL22;PI4KA;RTN4R;SEPT5","DGCR8;HIRA;PI4KA","AIFM3;CRKL;PI4KA;PRODH;SEPT5;SLC25A1","AIFM3;ARVCF;C22orf29;C22orf39;CLDN5;COMT;CRKL;DGCR14;DGCR2;DGCR6;DGCR6L;DGCR8;GNB1L;GP1BB;HIRA;KLHL22;LZTR1;MED15;MRPL40;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SERPIND1;SLC25A1;SLC7A4;SNAP29;THAP7;TRMT2A;TSSK2;TXNRD2;UFD1L;ZDHHC8;ZNF74","AIFM3;ARVCF;C22orf39;CLDN5;COMT;CRKL;DGCR2;DGCR6;DGCR6L;GP1BB;KLHL22;MRPL40;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SLC25A1;THAP7;UFD1L;ZDHHC8;ZNF74","GSC2;PI4KAP1;TBX1;TMEM191A;TMEM191B","ARVCF;CLDN5;CLTCL1;CRKL;DGCR14;DGCR2;DGCR8;HIRA;KLHL22;LZTR1;MED15;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SERPIND1;SLC25A1;SLC7A4;TBX1;THAP7;TSSK2;UFD1L;ZNF74","CRKL;HIRA;KLHL22;MED15;PRODH;RANBP1;SERPIND1;SLC7A4;UFD1L","CRKL;HIRA;MED15;PRODH;RANBP1;SERPIND1","CLTCL1;COMT;CRKL;DGCR14;P2RX6;PI4KA;RTN4R;SEPT5;TBX1","COMT;MED15;RTN4R;SERPIND1","CDC45;COMT;CRKL;HIRA;RANBP1;RTN4R;TBX1;TXNRD2","ARVCF;CRKL;DGCR2;HIRA;KLHL22;PI4KA;PRODH;RTN4R;SEPT5","AIFM3;ARVCF;CLDN5;COMT;CRKL;DGCR2;DGCR8;HIRA;KLHL22;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SLC25A1;TBX1;UFD1L;ZDHHC8","AIFM3;ARVCF;CDC45;CLDN5;COMT;CRKL;DGCR2;DGCR8;HIRA;KLHL22;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SLC25A1;TBX1;TXNRD2;UFD1L;ZDHHC8","-"]
["4271_1","european",22,17257787,19795780,"DUP",2537994,"AIFM3;ARVCF;BCRP2;C22orf25;C22orf29;C22orf39;CDC45;CLDN5;CLTCL1;COMT;CRKL;DGCR10;DGCR11;DGCR14;DGCR2;DGCR5;DGCR6;DGCR6L;DGCR8;DGCR9;FLJ39582;GNB1L;GP1BB;GSC2;HIRA;KLHL22;LOC150185;LOC150197;LOC400891;LZTR1;MED15;MGC16703;MIR1286;MIR1306;MIR185;MIR3618;MRPL40;P2RX6;P2RX6P;PI4KA;PI4KAP1;POM121L4P;PRODH;RANBP1;RIMBP3;RTN4R;SCARF2;SEPT5;SEPT5-GP1BB;SERPIND1;SLC25A1;SLC7A4;SNAP29;TBX1;THAP7;TMEM191A;TMEM191B;TRMT2A;TSSK2;TXNRD2;UFD1L;ZDHHC8;ZNF74","CRKL","CRKL;TSSK2","ARVCF;DGCR2;KLHL22;PI4KA;RTN4R;SEPT5","DGCR8;HIRA;PI4KA","AIFM3;CRKL;PI4KA;PRODH;SEPT5;SLC25A1","AIFM3;ARVCF;C22orf29;C22orf39;CLDN5;COMT;CRKL;DGCR14;DGCR2;DGCR6;DGCR6L;DGCR8;GNB1L;GP1BB;HIRA;KLHL22;LZTR1;MED15;MRPL40;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SERPIND1;SLC25A1;SLC7A4;SNAP29;THAP7;TRMT2A;TSSK2;TXNRD2;UFD1L;ZDHHC8;ZNF74","AIFM3;ARVCF;C22orf39;CLDN5;COMT;CRKL;DGCR2;DGCR6;DGCR6L;GP1BB;KLHL22;MRPL40;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SLC25A1;THAP7;UFD1L;ZDHHC8;ZNF74","GSC2;PI4KAP1;TBX1;TMEM191A;TMEM191B","ARVCF;CLDN5;CLTCL1;CRKL;DGCR14;DGCR2;DGCR8;HIRA;KLHL22;LZTR1;MED15;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SERPIND1;SLC25A1;SLC7A4;TBX1;THAP7;TSSK2;UFD1L;ZNF74","CRKL;HIRA;KLHL22;MED15;PRODH;RANBP1;SERPIND1;SLC7A4;UFD1L","CRKL;HIRA;MED15;PRODH;RANBP1;SERPIND1","CLTCL1;COMT;CRKL;DGCR14;P2RX6;PI4KA;RTN4R;SEPT5;TBX1","COMT;MED15;RTN4R;SERPIND1","CDC45;COMT;CRKL;HIRA;RANBP1;RTN4R;TBX1;TXNRD2","ARVCF;CRKL;DGCR2;HIRA;KLHL22;PI4KA;PRODH;RTN4R;SEPT5","AIFM3;ARVCF;CLDN5;COMT;CRKL;DGCR2;DGCR8;HIRA;KLHL22;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SLC25A1;TBX1;UFD1L;ZDHHC8","AIFM3;ARVCF;CDC45;CLDN5;COMT;CRKL;DGCR2;DGCR8;HIRA;KLHL22;PI4KA;PRODH;RANBP1;RTN4R;SEPT5;SLC25A1;TBX1;TXNRD2;UFD1L;ZDHHC8","-"]
["8630_201","european",22,32346124,32413987,"DEL",67864,"LARGE","LARGE","LARGE","LARGE","LARGE","-","LARGE","LARGE","-","-","-","-","-","-","-","LARGE","LARGE","LARGE","-"]
["2072_1","european",22,45159185,49582267,"DEL",4423083,"ACR;ADM2;ALG12;ARSA;BRD1;C22orf34;C22orf41;CELSR1;CERK;CHKB;CHKB-CPT1B;CPT1B;CRELD2;FAM116B;FAM19A5;FLJ46257;GRAMD4;HDAC10;IL17REL;KLHDC7B;LMF2;LOC100144603;LOC90834;MAPK11;MAPK12;MAPK8IP2;MIOX;MIR3201;MLC1;MOV10L1;NCAPH2;ODF3B;PANX2;PIM3;PLXNB2;PPP6R2;RABL2B;RPL23AP82;SBF1;SCO2;SELO;SHANK3;TBC1D22A;TRABD;TUBGCP6;TYMP;ZBED4","MAPK12","MAPK11;MAPK12","PPP6R2;SBF1;SHANK3","BRD1;CELSR1;FAM19A5;GRAMD4;NCAPH2;PLXNB2;SBF1","SBF1;SHANK3","ALG12;ARSA;BRD1;CELSR1;CERK;CHKB;CRELD2;FAM19A5;GRAMD4;HDAC10;LMF2;MAPK11;MAPK12;MAPK8IP2;MLC1;NCAPH2;ODF3B;PANX2;PIM3;PLXNB2;PPP6R2;SBF1;SCO2;SELO;TRABD;TUBGCP6;ZBED4","BRD1;CERK;FAM19A5;MAPK11;MAPK8IP2;MLC1;NCAPH2;PANX2;PIM3;PLXNB2;PPP6R2;SBF1;SCO2;SELO;ZBED4","ACR;MIOX;MOV10L1;SHANK3","ACR;BRD1;CELSR1;CERK;CRELD2;IL17REL;MAPK11;MAPK12;MAPK8IP2;MIOX;MLC1;PANX2;PIM3;PLXNB2;SHANK3","BRD1;CELSR1;IL17REL;MAPK11;MAPK12","MAPK11","CELSR1;HDAC10;MAPK11;MAPK12;MAPK8IP2;PANX2;PLXNB2;SHANK3","CELSR1;MAPK11;MAPK12;MAPK8IP2;PANX2;PLXNB2;SHANK3;TYMP","ADM2;CELSR1;MAPK12;PIM3;PLXNB2;SCO2;SHANK3;TUBGCP6;TYMP","CELSR1;PPP6R2;SBF1;SHANK3","ARSA;BRD1;CELSR1;CERK;FAM19A5;GRAMD4;MAPK11;MAPK12;MAPK8IP2;MLC1;NCAPH2;PANX2;PLXNB2;PPP6R2;SBF1;SCO2;SHANK3","ADM2;ARSA;BRD1;CELSR1;CERK;FAM19A5;GRAMD4;MAPK11;MAPK12;MAPK8IP2;MLC1;NCAPH2;PANX2;PIM3;PLXNB2;PPP6R2;SBF1;SCO2;SHANK3;TUBGCP6;TYMP","-"]
["6130_4","european",22,47996161,49512530,"DEL",1516370,"ADM2;ALG12;ARSA;BRD1;C22orf34;C22orf41;CHKB;CHKB-CPT1B;CPT1B;CRELD2;FAM116B;HDAC10;IL17REL;KLHDC7B;LMF2;LOC100144603;LOC90834;MAPK11;MAPK12;MAPK8IP2;MIOX;MLC1;MOV10L1;NCAPH2;ODF3B;PANX2;PIM3;PLXNB2;PPP6R2;SBF1;SCO2;SELO;SHANK3;TRABD;TUBGCP6;TYMP;ZBED4","MAPK12","MAPK11;MAPK12","PPP6R2;SBF1;SHANK3","BRD1;NCAPH2;PLXNB2;SBF1","SBF1;SHANK3","ALG12;ARSA;BRD1;CHKB;CRELD2;HDAC10;LMF2;MAPK11;MAPK12;MAPK8IP2;MLC1;NCAPH2;ODF3B;PANX2;PIM3;PLXNB2;PPP6R2;SBF1;SCO2;SELO;TRABD;TUBGCP6;ZBED4","BRD1;MAPK11;MAPK8IP2;MLC1;NCAPH2;PANX2;PIM3;PLXNB2;PPP6R2;SBF1;SCO2;SELO;ZBED4","MIOX;MOV10L1;SHANK3","BRD1;CRELD2;IL17REL;MAPK11;MAPK12;MAPK8IP2;MIOX;MLC1;PANX2;PIM3;PLXNB2;SHANK3","BRD1;IL17REL;MAPK11;MAPK12","MAPK11","HDAC10;MAPK11;MAPK12;MAPK8IP2;PANX2;PLXNB2;SHANK3","MAPK11;MAPK12;MAPK8IP2;PANX2;PLXNB2;SHANK3;TYMP","ADM2;MAPK12;PIM3;PLXNB2;SCO2;SHANK3;TUBGCP6;TYMP","PPP6R2;SBF1;SHANK3","ARSA;BRD1;MAPK11;MAPK12;MAPK8IP2;MLC1;NCAPH2;PANX2;PLXNB2;PPP6R2;SBF1;SCO2;SHANK3","ADM2;ARSA;BRD1;MAPK11;MAPK12;MAPK8IP2;MLC1;NCAPH2;PANX2;PIM3;PLXNB2;PPP6R2;SBF1;SCO2;SHANK3;TUBGCP6;TYMP","-"]
["14291_4120","european",22,49468716,49485255,"DEL",16540,"SHANK3","-","-","SHANK3","-","SHANK3","-","-","SHANK3","SHANK3","-","-","SHANK3","SHANK3","SHANK3","SHANK3","SHANK3","SHANK3","-"]
["16079_1571066001","european",22,49470371,49567383,"DEL",97013,"ACR;RABL2B;RPL23AP82;SHANK3","-","-","SHANK3","-","SHANK3","-","-","ACR;SHANK3","ACR;SHANK3","-","-","SHANK3","SHANK3","SHANK3","SHANK3","SHANK3","SHANK3","-"]
["16076_1571045001","european","X",22768481,23133948,"DEL",365468,"DDX53","DDX53","DDX53","-","-","-","-","-","DDX53","-","-","-","-","-","-","-","-","-","-"]
["20013_1075001","european","X",153239048,153521797,"DUP",282750,"ATP6AP1;CTAG1A;CTAG1B;DNASE1L1;EMD;FAM3A;FAM50A;FLNA;G6PD;GDI1;IKBKG;LAGE3;NCRNA00204;NCRNA00204B;PLXNA3;RPL10;SLC10A3;SNORA70;TAZ;UBL4A","FLNA","FLNA;IKBKG","-","FLNA;UBL4A","FLNA;G6PD;GDI1;PLXNA3;UBL4A","ATP6AP1;DNASE1L1;EMD;FAM3A;FAM50A;FLNA;G6PD;GDI1;LAGE3;PLXNA3;RPL10;UBL4A","ATP6AP1;EMD;FAM3A;FAM50A;FLNA;G6PD;GDI1;LAGE3;RPL10;UBL4A","CTAG1A","CTAG1A;CTAG1B;DNASE1L1;FAM3A;FLNA;G6PD;GDI1;IKBKG;RPL10;SLC10A3;TAZ","FLNA;G6PD;IKBKG","FLNA","PLXNA3","PLXNA3","EMD;PLXNA3;TAZ","FLNA;UBL4A","DNASE1L1;EMD;FLNA;G6PD;GDI1;LAGE3;PLXNA3;UBL4A","DNASE1L1;EMD;FLNA;G6PD;GDI1;LAGE3;PLXNA3;TAZ;UBL4A","FLNA;IKBKG"]
["8430_204","other",15,20301669,20777695,"DEL",652722,"CYFIP1;NIPA1;NIPA2;TUBGCP5;WHAMML1","CYFIP1","CYFIP1;TUBGCP5","-","-","CYFIP1","CYFIP1;NIPA1;NIPA2","NIPA1;NIPA2","-","CYFIP1;NIPA1;NIPA2","-","-","CYFIP1","CYFIP1","CYFIP1;TUBGCP5","-","CYFIP1","CYFIP1;TUBGCP5","-"]
["6356_5","european",1,2118508,2325536,"DEL",207029,"MORN1;SKI;LOC100129534;RER1","SKI","SKI;RER1","SKI","-","-","MORN1;SKI;RER1","SKI;RER1","-","SKI;RER1","RER1","-","SKI","SKI","SKI","SKI","SKI;RER1","SKI;RER1","SKI"]
["3616_3","european",3,9474320,9498362,"DEL",24043,"SETD5","SETD5","SETD5","SETD5","-","-","SETD5","-","-","SETD5","SETD5","-","-","-","-","SETD5","SETD5","SETD5","-"]
["9756_201","other",9,132572435,132597937,"DEL",25503,"ABL1","ABL1","ABL1","-","ABL1","-","ABL1","ABL1","-","ABL1","ABL1","ABL1","ABL1","ABL1","ABL1","ABL1","ABL1","ABL1","-"]
["14237_2650","european",9,103456776,107140273,"DEL",3683498,"ABCA1;CYLC2;GRIN3A;LOC286367;NIPSNAP3A;NIPSNAP3B;OR13C2;OR13C3;OR13C4;OR13C5;OR13C8;OR13C9;OR13D1;OR13F1;SLC44A1;SMC2","ABCA1","ABCA1;SMC2","-","SMC2","-","GRIN3A;NIPSNAP3A;SLC44A1;SMC2","NIPSNAP3A;SLC44A1","CYLC2;OR13C2;OR13C3;OR13C4;OR13C5;OR13C8;OR13C9;OR13D1;OR13F1","ABCA1;GRIN3A;OR13C8;OR13C9;OR13F1;SLC44A1;SMC2","ABCA1;GRIN3A;SMC2","ABCA1;SMC2","GRIN3A","GRIN3A","-","-","GRIN3A;SMC2","GRIN3A;SMC2","-"]

{"sheet":"Table S14B. Gene characteriz.","index":2,"n_rows":114,"n_cols":41,"rows_kept":114,"cut":false,"hidden":false,"merged":[]}
["#auto","sampleID|chr#:star-end","NetBag2g_113g_w10kbfk","Function (EntrezGene or OMIM)","Known.ASD/ ID.genes","LOF.dn.SNV","rec.SNV consang.fams","Neurodevelop disorder (empirical)","Neurological disorder (empirical)","Non-neuro develop disorder (empirical)","Disease (GeneReviews)","OMIM (morbid)","#HPO_het_dom_Gene_symbol","#HPO_hom_rec_Gene_symbol","#HPO_x_XL_Gene_symbol","Literature","PMID","MGI","#MPO_het_dom_Gene_symbol","#MPO_hom_rec_Gene_symbol","#MPO_x_XL_Gene_symbol","mouse-neuro-phenotypes","Synapse_Grant-full","Synapse_Grant-consensus","FMRP_Darnell","FMRP_Ascano","Brain_RNAseq.Exp.Levels_NCX","Brain_RNAseq.Stage_NCX","#CNVdisrupted-by-101dn","CNVtype_w_disrupted","DEL/DUPdisrupt_OR_DEL-pHI>0.35","Haploinsufficiency Index","Mechanism","GeneMania","STRING","NeuroF","NeuroF_EM_Cpj","Development_EM","Candidate_stringent","Candidate_broad","Candidate_broad_dev"]
[1,"6259_3|9:139523184-140273252","EHMT1","Histone methyltransferase that is part of the E2F6 complex, which represses transcription.","ASD, ID (dom)","-","-","Yes","-","Yes","Kleefstra syndr","#610253","EHMT1","-","-","9q34.3-microdeletions and/or intragenic EHMT1 mutations cause Kleefstra syndr. Characterized by ID, distinctive facial features, epilepsy/febrile seizures,ASD and extreme apathy or catatonic-like features after puberty. It may also present a variable number of malformations.",21910222,"Heterozygous null mice display decreased exploration in a new environment. Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E10.","EHMT1","-","-","EHMT1:nervous system phenotype;growth/size phenotype;embryogenesis phenotype;behavior/neurological phenotype;mortality/aging","-","-","Yes","Yes","MED","Prenatal-biased","-","NAHR, DEL-9q34","-","EHMT1|0.167","SegDup","n/a","n/a",0,0,1,1,1,1]
[2,"13050_593|15:21190624-26203954; 17035_1|15:20274130-26120360; 20069_1328001|15:20203578-26209270; 20187_1464001|15:18811937-26209270; 8630_201|15:19800798-26209270","UBE3A","E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system.","ASD, ID (dom, imprinted)","-","-","Yes","-","-","Angelman syndr","#105830","UBE3A","-","-","Intragenic UBE3A mutations or deletions, uniparental disomy, or an imprinting defect of 15q11.2-q13 can cause Angelman syndr. Angelman syndr is characterized by severe ID, severe speech impairment, gait ataxia and a unique behavior",21204213,"Mice with maternally inherited targeted null mutations exhibit reduced brain weight, impaired motor function, inducible seizures, learning deficits, abnormal hippocampal electroencephalographic recordings, and severely impaired long-term potentiation.","UBE3A","-","-","UBE3A:nervous system phenotype;growth/size phenotype;endocrine/exocrine gland phenotype;cellular phenotype;behavior/neurological phenotype;reproductive system phenotype;mortality/aging;integument phenotype","-","-","-","-","HI","Prenatal-biased","-","NAHR, DUP-15q11-q13","yes","UBE3A|0.374","SegDup","n/a","n/a",1,0,1,0,1,1]
[3,"13123_1403|9:98998-3682923","SMARCA2","Component of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. ","ASD, ID (dom)","-","-","Yes","-","Yes","Coffin-Siris syndr and Nicolaides-Baraitser syndr","#135900\n#601358","-","-","-","Intragenic mutations of SMARCA2 cause Coffin-Siris syndr and Nicolaides-Baraitser syndr. Both CSS and NBS are characterized by moderate to severe ID, epilepsy, behavioural probelms and a variable combination of dysmorphism and malformations","22366787; 22426308","Mice homozygous for a targeted mutation in this gene may exhibit infertility and a slightly increased body weight in some genetic backgrounds.","-","-","-","SMARCA2:renal/urinary system phenotype;muscle phenotype;homeostasis/metabolism phenotype;growth/size phenotype;digestive/alimentary phenotype;reproductive system phenotype;skeleton phenotype;mortality/aging;integument phenotype","-","-","Yes","-","HI","Unbiased","-","DEL","yes","SMARCA2|1","Not_SegDup","n/a","n/a",1,0,1,1,1,1]
[4,"13017_223|2:50539877-50730546; 13037_463|2:51002576-51157742; 13153_1703|2:50990306-51222043; 13216_2383|2:50968208-51214171; 14068_1180|2:50493827-50677835","NRXN1","Neurexins function in the vertebrate nervous system as cell adhesion molecules and receptors.","ASD, ID (dom)","YES, ASD","-","Yes","-","-","Pitt-Hopkins-Like syndr and susceptibility to Schizophrenia","#614325\n#614332","-","NRXN1","-","Homozygous mutations of NRXN1 cause PHLS, which is characterized by severe ID, ASD, encephalopathic epilepsy and behaviour abnormalities. ",21262241,"Mice homozygous for a knock-out allele exhibit reduced Ca(2+)-dependent binding of alpha-latrotoxin to brain membranes. Isolated synaptosomes display only a small reduction in alpha-latrotoxin -triggered glutamate release in the absence of Ca(2+) but show a major decrease in the presence of Ca(2+).","-","NRXN1","-","NRXN1:nervous system phenotype;respiratory system phenotype;mortality/aging","Yes","Yes","Yes","-","HI","Unbiased","Yes","DEL_disr, DUP_disr","yes","NRXN1|0.075","Not_SegDup","n/a","n/a",1,1,1,1,1,1]
[5,"5237_3|11:70154458-70220632; 6319_3|11:70119917-70187872; 6325_3|11:70077507-70506315","SHANK2","Synaptic protein that functions as s molecular scaffold in the postsynaptic density","ASD (dom)","YES, ASD","-","Yes","-","-","ASD","#613436","-","-","-","Inherited and de novo SHANK2 variants are associated with ASD, and known to impair neuronal morphogenesis and physiology",21994763,"Mice homozygous for null mutations display hyperactivity and abnormal social behavior. Mice homozygous for one null allele also display partial postnal lethality and limb grasping.","SHANK2","-","-","-","Yes","Yes","Yes","-","MED","Unbiased","Yes","DEL_disr","yes","SHANK2|0.292","Not_SegDup","n/a","n/a",1,1,0,1,1,1]
[6,"5353_3|6:33399849-33512042","SYNGAP1","Major component of the postsynaptic density","ASD, ID (dom)","YES, ASD, ID, SCZ","-","Yes","-","-","ID","#612621","-","-","-","De novo heterozygous SYNGAP1 mutations cause nonsyndromic ID","21237447","Homozygous mutant mice exhibit postnatal lethality, and by P3-P4, exhibit small body size and brain, reduced movement and do not feed.","SYNGAP1","-","-","SYNGAP1:nervous system phenotype;growth/size phenotype;behavior/neurological phenotype;mortality/aging","Yes","Yes","Yes","-","HI","Unbiased","Yes","DEL_disr","yes","SYNGAP1|0.369","Not_SegDup","n/a","n/a",1,1,1,1,1,1]
[7,"20013_1075001|X:153239048-153521797","FLNA","Actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins","ID (xl)","-","-","Yes","-","Yes","FG syndr, Frontometaphyseal dysplasia,  X-Linked Periventricular Heterotopia, Meknick-Needles syndr and Otopalatodigital Spectrum Disorders\n ","#300321\n#305620\n#300049; #300537\n#309350\n#311300; #304120","-","-","FLNA","Mutations in FLNA cause a wide spectrum of congenital anomalies (including migraitonal disroders) and ID. The disease is more severe (and sometimes lethal) in males when compared to females ","12612583","Females heterozygous for an X-linked, ENU-induced mutation exhibit dilated pupils and milder cardiac, sternum, and palate defects than males. Hemizygous males are inviable and exhibit incomplete septation of the outflow tract, septal defects, cleft palate and incomplete fusion of the sternum.","-","-","-","FLNA:normal phenotype;nervous system phenotype;liver/biliary system phenotype;homeostasis/metabolism phenotype;growth/size phenotype;digestive/alimentary phenotype;craniofacial phenotype;cardiovascular system phenotype;behavior/neurological phenotype;immune system phenotype;respiratory system phenotype;reproductive system phenotype;skeleton phenotype;vision/eye phenotype;hematopoietic system phenotype;mortality/aging","Yes","Yes","-","Yes","MED","Unbiased","Yes","DUP_disr","yes","FLNA|0.752","Not_SegDup","n/a","n/a",0,0,0,1,1,1]
[8,"20013_1075001|X:153239048-153521797","IKBKG","Regulatory subunit of the inhibitor of kappaB kinase complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity and cell survival","ID (xl)","-","-","Yes (Incontinentia Pigmenti)","-","Yes","Incontinentia Pigmenti, Immunodeficiency without Anhidrotic Ectodermal Dysplasia, Hypohidrotic Ectodermal Dysplasia with Immune Deficiency, X-Linked Familial Atypical Mycobacteriosis 1","#308300\n#300584\n#305100\n#300636","-","-","IKBKG","Heterozygous intragenic mutations of IKBKG are linked to Incontinentia Pigmenti, Immunodeficiency without Anhidrotic Ectodermal Dysplasia, Hypohidrotic Ectodermal Dysplasia with Immune Deficiency and X-Linked Familial Atypical Mycobacteriosis. In females the disorder affects the skin, hair, teeth, nails, eyes, and central nervous system, including ID. Usually is lethal in males.","22564885","Males hemizygous for targeted null mutations exhibit embryonic lethality by embryonic day 13.5 from apoptotic liver damage. Heterozygous females show patchy skin lesions with granulocyte infiltration, growth retardation, and shortened lifespan.","-","-","IKBKG","IKBKG:pigmentation phenotype;tumorigenesis;normal phenotype;liver/biliary system phenotype;adipose tissue phenotype;homeostasis/metabolism phenotype;growth/size phenotype;cellular phenotype;cardiovascular system phenotype;behavior/neurological phenotype;immune system phenotype;reproductive system phenotype;hematopoietic system phenotype;mortality/aging;integument phenotype","-","-","-","-","MED","Unbiased","-","DUP","-","IKBKG|0.372","Not_SegDup","n/a","n/a",0,0,0,0,0,0]
[9,"13027_353|2:144837809-145315383","ZEB2","DNA-binding transcriptional repressor that interacts with activated SMADs.","ID (dom)","-","-","Yes","-","Yes","Mowat-Wilson syndr","#235730","-","ZEB2","-","Heterozygous mutations or deletions of the ZEB2 gene cause Mowat-Wilson syndr, which is charracterized by distinctive facila features, congenital anomalies (including corpus callosum agenesis), ID and epilepsy","19215041","Homozygous null mutants exhibit a variety of defects at embryonic day 8.5 and die between embryonic days 9.5 and 10.5.","-","-","-","-","-","-","Yes","-","HI","Prenatal-biased","-","DUP","-","ZEB2|0.841","Not_SegDup","n/a","n/a",1,0,1,1,1,1]
[10,"6356_5|1:2118508-2325536","SKI","repressor of TGF-beta signalin","ID (dom)","-","-","Yes","-","Yes","Shprintzen-Goldberg Syndrome","#182212\n#182212","SKI","-","-","Mutations in SKI cause Shprintzen-Goldberg",23023332,"Homozygous null embryos die during late gestation and exhibit neural tube defects, craniofacial anomalies, and reduced skeletal muscle mass. Haploinsufficient mice have an increased susceptibility to tumorigenesis.","SKI","-","-","SKI: tumorigenesis;nervous system phenotype;muscle phenotype;limbs/digits/tail phenotype;homeostasis/metabolism phenotype;growth/size phenotype;embryogenesis phenotype;craniofacial phenotype;cellular phenotype;cardiovascular system phenotype;skeleton phenotype;vision/eye phenotype;mortality/aging","-","-","Yes","-","HI","Prenatal-biased","-","DEL","-","SKI|0.175","Not_SegDup","Physical interaction and pathway with GLI3 (Greig cephalopolysyndactyly syndrome -\n#175700; Pallister-Hall syndrome - #146510), GLI2 (Holoprosencephaly - #610829), SMAD3  (Loeys-Dietz syndrome - *603109)","Association with SMAD3  (Loeys-Dietz syndrome - *603109) and SAMD4 (Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome - #175050)",1,1,1,1,1,1]
[11,"8534_201|10:45633089-51564756","ERCC6","DNA-binding protein that participates in the transcription-coupled excision repair","ID (rec)","-","-","Yes","-","Yes","AR Cockayne syndr, CerebroOculoFacioSkeletal syndr, Age-Related Macular Degeneration","#214150\n#133540\n#613761","-","ERCC6","-","Homozygous mutations of ERCC6 cause disorders characterized by growth retardation, intellectual disability and congenital anomalies. ","20687508","Homozygous mutant mice exhibit UV sensitivity, inactivation of transcription-coupled repair, increased incidence of induced skin and eye tumors, circling behavior, impaired coordination and lower body weight.","-","ERCC6","-","ERCC6:tumorigenesis;nervous system phenotype;muscle phenotype;liver/biliary system phenotype;limbs/digits/tail phenotype;adipose tissue phenotype;homeostasis/metabolism phenotype;growth/size phenotype;cellular phenotype;behavior/neurological phenotype;skeleton phenotype;vision/eye phenotype;mortality/aging;integument phenotype","-","-","-","-","MED","Unbiased","-","NAHR, DEL-10q","-","-","SegDup","n/a","n/a",1,0,0,0,1,1]
[12,"20180_1704001|21:43018846-43444308","CBS","enzyme that converts homocysteine to cystathionine","ID (rec)","-","-","Yes","-","Yes","Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency","#236200","-","CBS","-","Mutations in CBS cause classical homocystinuria",23124942,"Homozygous targeted mutants are severely growth retarded and die within 5 weeks of birth with enlarged multinucleate hepatocytes filled with lipid and massively elevated plasma homocysteine levels. Heterozygotes have twice normal homocysteine levels, but survive and breed.","-","CBS","-","CBS: renal/urinary system phenotype;muscle phenotype;liver/biliary system phenotype;limbs/digits/tail phenotype;homeostasis/metabolism phenotype;growth/size phenotype;endocrine/exocrine gland phenotype;embryogenesis phenotype;craniofacial phenotype;cellular phenotype;cardiovascular system phenotype;behavior/neurological phenotype;immune system phenotype;respiratory system phenotype;reproductive system phenotype;skeleton phenotype;vision/eye phenotype;hematopoietic system phenotype;mortality/aging;integument phenotype","-","-","-","-","HI","Prenatal-biased","-","DUP","-","CBS|0.452","Not_SegDup","Predicted interaction with SMARCA4 (autosomal dominant intellectual disability - \n#614609)","Association with HTT (Huntington disease - #143100)",1,0,0,0,1,1]
[13,"8658_201|1:98175622-100923952","DBT","enzyme involved in the breakdown of branched-chain amino acids","ID (rec)","-","-","Yes","-","Yes","Maple Syrup Urine Disease","#248600","-","DBT","-","DBT encodes a subunit of the branched-chain alpha-keto acid dehydrogenase complex (BCKD); mutations of the BCKD complex causes Maple Syrup Urine Disease",16365091,"Homozygous mutation of this gene results in postnatal lethality, pallor, respiratory distress, and an increase in branched-chain amino acids in the blood and urine. Homozygotes model Maple Syrup Urine Disease","-","DBT","-","DBT: renal/urinary system phenotype;homeostasis/metabolism phenotype;behavior/neurological phenotype;respiratory system phenotype;mortality/aging;integument phenotype","Yes","-","-","-","MED","Unbiased","-","DEL","-","DBT|0.303","Not_SegDup","x","x",0,0,0,0,1,1]
[14,"5046_3|20:8607242-8637441","PLCB1","Catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate","ID (rec)","-","-","Yes","-","-","Early Infantile Epileptic Encephalopathy","#613722","-","-","-","Homozygous mutations in the PLCB1 gene cause Early Infantile Epileptic Encephalopathy. Characterized by early recurrent and refractory generalized seizures with concomitant developmental regression","20833646","Homozygotes for a targeted null mutation exhibit spontaneous seizures and high mortality around 3 weeks of age. Mutant males show exhibit sperm with a reduced acrosome reaction rate and fertilizing capacity in vitro and decreased fertility in vivo.","-","PLCB1","-","PLCB1:nervous system phenotype;renal/urinary system phenotype;limbs/digits/tail phenotype;hearing/vestibular/ear phenotype;growth/size phenotype;endocrine/exocrine gland phenotype;craniofacial phenotype;behavior/neurological phenotype;reproductive system phenotype;skeleton phenotype;mortality/aging","Yes","Yes","Yes","Yes","MED","Postnatal-biased","Yes","DEL_disr","yes","PLCB1|0.396","Not_SegDup","n/a","n/a",1,1,1,1,1,1]
[15,"8630_201|22:32346124-32413987","LARGE","Glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains","ID (rec)","-","-","Yes","-","Yes","Muscular Dystrophy-Dystroglycanopathy type A6, type B6 and type A1","613154\n608840\n236670","-","LARGE","-","Homozygous mutations in LARGE cause a spectrum of disrders that affects the muscles (dystrophy), eyes (developmental anomalies) and brain (including cobblestone lissencephaly)","15021250","Homozygotes exhibit a progressive myopathy, abnormal posture, thoracic kyphosis, calcium deposits in muscle, loss of Schwann cells and myelin, eye and CNS defects, deafness, reduced growth, and death around 4 months","LARGE","-","-","LARGE:nervous system phenotype;muscle phenotype;homeostasis/metabolism phenotype;hearing/vestibular/ear phenotype;growth/size phenotype;digestive/alimentary phenotype;craniofacial phenotype;cardiovascular system phenotype;behavior/neurological phenotype;immune system phenotype;reproductive system phenotype;skeleton phenotype;vision/eye phenotype;mortality/aging","-","-","Yes","Yes","HI","Unbiased","Yes","DEL_disr","yes","LARGE|0.067","Not_SegDup","n/a","n/a",0,0,0,1,1,1]
[16,"13050_593|15:21190624-26203954; 17035_1|15:20274130-26120360; 20069_1328001|15:20203578-26209270; 20187_1464001|15:18811937-26209270; 8630_201|15:19800798-26209270","SNRPN","small nuclear ribonucleoprotein complex; involved in pre-mRNA processing","-","-","-","Yes","-","-","Prader-Willi Syndrome","#176270","-","-","-","Loss of the paternal allele of SNURF-SNRPN leads to Prader-Willi syndrome",23390487,"Homozygotes for targeted intragenic deletions are phenotypically normal. Deletions that also encompass neighboring genes on the paternal chromosome exhibit growth retardation, hypotonia, and high mortality.","SNRPN","-","-","SNRPN: normal phenotype;adipose tissue phenotype;homeostasis/metabolism phenotype;growth/size phenotype;cellular phenotype;behavior/neurological phenotype;reproductive system phenotype;mortality/aging","-","-","-","-","HI","Postnatal-biased","-","NAHR, DUP-15q11-q13","-","SNRPN|0.607","SegDup","x","Association with SMN2 (spinal muscular atrophy type3 - #253400)",0,0,0,0,1,1]
[17,"18133_302|6:69540429-73375020","RIMS1","Member of the RAS gene superfamily, which regulates synaptic vesicle exocytosis","-","YES, ASD","-","Yes","-","-","Cone-Rod Dystrophy","603649","-","-","-","RIM determines Ca²+ channel density and vesicle docking at the presynaptic active zone. It has been associated with schizophrenia\n","20392954; 22753485; 21262468","Mice homozygous for disruptions in this gene display defects in maternal care and abnormalities in synaptic transmission in the central nervous system.","-","RIMS1","-","RIMS1:normal phenotype;nervous system phenotype;homeostasis/metabolism phenotype;behavior/neurological phenotype;skeleton phenotype;mortality/aging","Yes","Yes","-","-","MED","Postnatal-biased","-","DUP","-","RIMS1|0.514","Not_SegDup","n/a","n/a",1,1,0,0,1,1]
[18,"6248_3|6:86352577-86376159","SYNCRIP","Member of the cellular heterogeneous nuclear ribonucleoprotein  (hnRNP) family","-","YES, ID","-","Yes","-","-","x","x","-","-","-","It is a component of dendritically localized mRNPs, binds to the translation regulator BC200 RNA\n",18045242,"x","-","-","-","-","Yes","-","-","-","HI","Prenatal-biased","Yes","DEL_disr","yes","SYNCRIP|0.973","Not_SegDup","n/a","n/a",0,0,0,1,1,1]
[19,"14414_5230|2:230486629-230547253","TRIP12","Thyroid hormone receptor interactor 12","-","YES, ASD","-","-","-","Yes","x","x","-","-","-","The E3 ubiquitin ligase activity of Trip12 is essential for mouse embryogenesis.",22028794,"Mice homozygous for a targeted allele exhibit complete embryonic lethality during organogenesis associated with embryonic growth retardation and abnormal placenta development.","-","-","-","-","-","-","Yes","-","MED","Unbiased","Yes","DEL_disr","yes","TRIP12|0.819","Not_SegDup","n/a","n/a",0,0,0,1,1,1]
[20,"3616_3|3:9474320-9498362","SETD5","likely chromatine remodeler","-","YES, ID","-","Yes","-","-","-","-","-","-","-","Refining of 3p25.3 deletion syndrome points to SETD5 as being one of the critical genes.",23613140,"x","-","-","-","-","-","-","Yes","-","MED","Prenatal-biased","yes","DEL","yes","SETD5|0.399","Not_SegDup","Co-Expression with MED12 (Lujan-Fryns syndrome - #309520; Opitz-Kaveggia - #305450) and MLL (Wiedemann-Steiner syndrome - #605130)","x",0,0,0,1,1,1]
[21,"6101_4|15:74735339-74929817","SCAPER","Cyclin A/Cdk2 regulatory protein that transiently maintains cyclin A in the cytoplasm","-","-","YES, ID","-","-","-","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","MED","Unbiased","Yes","DEL_disr","yes","SCAPER|0.131","Not_SegDup","n/a","n/a",0,0,0,0,0,0]
[22,"16040_1571029001|15:28450423-30303265","CHRNA7","Nicotinic acetylcholine receptorsm which is a ligand-gated ion channels that mediate fast signal transmission at synapses","-","-","-","Yes","-","-","Susceptibility to generalized idiopathic epilepsy and susceptibility to Schizophrenia","%604827; %613025","-","-","-","In the context of 15q13.3 microdeletion, CHRNA7 has been considered a good candidate for epilepsy. It has also been assocaited to schizophrenia.","19136953; 19909231","Nullizygous mice lack hippocampal fast nicotinic currents but show nicotine-induced seizures as well as altered anxiety behavior, fertility defects, airway basal cell hyperplasia. and higher TNF sythesis when endotoxemic. Newborns homozygous for a knock-in allele die with increased neuron apoptosis.","-","CHRNA7","-","CHRNA7:nervous system phenotype;homeostasis/metabolism phenotype;behavior/neurological phenotype;immune system phenotype;respiratory system phenotype;reproductive system phenotype;mortality/aging","-","-","-","-","MED","Unbiased","-","NAHR, DEL-15q13","yes","CHRNA7|0.409","SegDup","n/a","n/a",1,1,1,0,1,1]
[23,"16076_1571045001|X:22768481-23133948","DDX53*","DEAD-box helicase protein family. Other members of this family participate in ATP-dependent RNA unwinding","-","-","-","Yes","-","-","*non-coding RNA (PTCHD1-AS) overlaps with the DDX53 gene, and it is associated with ASD","%209850","-","-","-","Disruption of the PTCHD1 locus on Xp22.11 by deletions in males is seen in cases with ASD and/or ID\n",2084428,"x","-","-","-","-","-","-","-","-","veryLOW_UNEXP","NA","-","DEL","-","DDX53|0.019","Not_SegDup","n/a","n/a",0,0,0,0,0,0]
[24,"17009_1|14:78575296-78596793","NRXN3","Receptors and cell adhesion molecules in neurons","-","-","-","Yes","-","-","x","x","-","-","-","NRXN3 encodes neuronal adhesion protein that have important roles in synapse development and function. Rare exonic deletions found in cases with autism spectrum disorder",22209245,"Twenty percent of mice homozygous for a knock-out allele die postnatally prior to 20 days of age.","-","-","-","-","Yes","-","Yes","-","MED","Postnatal-biased","-","DEL","yes","NRXN3|0.504","Not_SegDup","n/a","n/a",1,1,1,1,1,1]
[25,"5370_3|7:153775586-153844747","DPP6","Binds to specific voltage-gated K+ channels and alters their expression and biophysical properties","-","-","-","Yes","-","-","Paroxysmal familial Ventricular fibrillation","#612956","-","-","-","Point mutations and CNVs encompassing DPP6 have been identified in patients with ASD and ID","18252227; 20844286","Mice homozygous for a knock-out allele exhibit loss of A-type K+ current gradients in distal dendrites.","-","DPP6","-","-","Yes","-","-","-","HI","Unbiased","Yes","DEL_disr","yes","DPP6|0.104","Not_SegDup","Physical interaction and CoLocalization with PRNP gene (Gerstmann-Straussler Disease #137440)","n/a",0,0,0,0,1,1]
[26,"8612_201|6:162588879-162629938","PARK2","Component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. ","-","-","-","Yes","Yes","-","AR Juvenile Parkinson Disease","#600116","-","-","-","PARK2 copy number aberrations in children presenting with ASD","21360662; 19404257","Dopamine and glutamate transmission are impaired in some targeted null mice, resulting in decreased exploratory behavior. These mice show decreased body weight and temperature. Park2 is inactivated as part of a large deletion in the quaking mouse, a dysmyelinating mutant with a pronounced tremor","-","PARK2","-","-","-","-","-","-","MED","Postnatal-biased","Yes","DEL_disr","yes","PARK2|0.175","Not_SegDup","Physical interaction and Pathway with CASK gene (FG syndr - #300422, ID and microcephaly with pontine and cerebellar hypoplasia - #300749, ID with or without nystagmus - #300422), PINK1 gene (AR Early Onset Parkinson Disease - #605909); LRRK2 gene (AD Parkinson Disease - #607060)","n/a",1,1,0,0,0,1]
[27,"8638_201|14:35203374-35369853","RALGAPA1 (=GARNL1)","Ral GTPase activating protein, alpha subunit 1 (catalytic)","-","-","-","Yes","-","-","x","x","-","-","-","RALGAPA1 haploinsufficiency has been implicated in development delay; knockdown in zebrafish resulted in brain developmental delay; 2.2-Mb deletion (14q13.1q13.3) was identified in a patient with developmental delay and intractable epilepsy where TULIP was the only gene highly expressed in the brain. \n","19733229; 15498464; 22581785","x","-","-","-","-","Yes","-","Yes","-","MED","Unbiased","Yes","DEL_disr","yes","RALGAPA1|0.646","Not_SegDup","x","n/a",0,0,0,0,0,0]
[28,"14070_1230|15:91200007-91283004","CHD2","The CHD family of proteins is characterized by the presence of chromatin organization modifier domains and SNF2-related helicase/ATPase domains.","-","-","-","Yes","-","Yes","x","x","-","-","-","Deletion of the RMGA and CHD2 genes in a child with epilepsy and mental deficiency ",22178256,"Mice homozygous for a gene trap allele exhibit early postnatal lethality associated with fetal growth retardation. Mice heterozygous for a gene trap allele exhibit postnatal lethality and premature death after weaning associated with growth retardation and multi-organ defects.","CHD2","-","-","CHD2:tumorigenesis;renal/urinary system phenotype;muscle phenotype;liver/biliary system phenotype;adipose tissue phenotype;homeostasis/metabolism phenotype;growth/size phenotype;endocrine/exocrine gland phenotype;cellular phenotype;cardiovascular system phenotype;behavior/neurological phenotype;immune system phenotype;respiratory system phenotype;skeleton phenotype;hematopoietic system phenotype;mortality/aging;integument phenotype","-","-","-","-","MED","Unbiased","Yes","DEL_disr","yes","CHD2|0.496","Not_SegDup","CoExpression and Predicted inteeraction with EIF2B5 gene (Leukoencephalopathy with vanishing white matter, AR - #603896)","n/a",0,0,0,0,1,1]
[29,"8677_201|4:94659049-95289667","GRID2","Member of the family of ionotropic glutamate receptors, which are the predominant excitatory neurotransmitter receptors in the mammalian brain.","-","-","-","Yes","Yes","-","x","x","-","-","-","Glutamate receptor δ2 regulates mGluR1-mediated synaptic transmission in cerebellar Purkinje neurons. It has also been included as one of genes of interest in a patient with ID and multiple malformations.\n","23115168; 22847869; 22457515\n","Homozygotes for multiple spontaneous and targeted null mutations exhibit ataxia and impaired locomotion associated with cerebellar Purkinje cell abnormalities and loss, and on some backgrounds, male infertility due to lack of zona penetration by sperm. Heterozigous mice for GRID2 (Grid2Lc/Grid2+)present decreased exploration of new environments and hyperactivyty.  They also have an abnormal endocrinological/metabolic response to stress (LPS-challenge). Other mutants (Grid2Lc/Grid2+B6CBACa Aw-J/A-Grid2Lc/J) present abnormal grooming behavior and ataxia.","GRID2","-","-","-","-","-","-","-","MED","Unbiased","Yes","DUP_disr","yes","GRID2|0.282","Not_SegDup","Physical interaction with GRIK2 gene (ID rec -  #611092)","n/a",1,0,0,0,1,1]
[30,"17035_1|15:20274130-26120360; 20069_1328001|15:20203578-26209270; 20187_1464001|15:18811937-26209270; 8430_204|15:20301669-20777695; 8630_201|15:19800798-26209270; 9759_201|15:19777876-20778963","TUBGCP5","microtubules","-","-","-","Yes","-","-","-","-","-","-","-","TUBGCP5 is one of the 4 genes encompassed in the recurrent 15q11.2 BP1-BP2 CNV, likely contributing for the behavioral disturbances associated with 15q11.2 deletion and duplications","23633446; 21187176; 19328872; 17268193; 16982806 ","x","-","-","-","-","-","-","-","-","MED","Unbiased","-","NAHR, DEL/DUP-15q11.2","-","-","SegDup","Physical interaction and pathway with TUB1 (Cortical dysplasia - *191135)","Association with TUB1 (Cortical dysplasia - *191135)",0,0,1,0,0,1]
[31,"5444_3|17:77785939-77849717","CSNK1D","Casein kinase I; implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair.","-","-","-","Yes","-","Yes","Familial advanced sleep phase syndr","#604348 ","-","-","-","CSNK1D may play a role in the regulatiion of circadian rhythmicity by post-translation modification of mammalian clock proteins hPER1 and 2.  ",11165242,"Homozygous null mice die 1.5 to 5 days after birth and fetal weight is significantly smaller than controls. Heterozygous mice for CSNKD1 (Csnk1dtm1.1Drw/Csnk1d+) present prolonged circadian rythm. However, other mutants (Csnk1dGt(TEA020)Byg/Csnk1d+) have a normal behavior/neurological phenotype.","CSNK1D","-","-","-","Yes","-","-","-","HI","Unbiased","-","DEL","yes","CSNK1D|0.95","Not_SegDup","x","Association with GJA1 gene (OculoDentoDigital syndr - #164200)",0,0,1,1,1,1]
[32,"5290_3|8:704383-1521910","DLGAP2","Membrane-associated guanylate kinases localized at postsynaptic density in neuronal cells.","-","-","-","Yes","-","-","Susceptibility to Autism","%209850","-","-","-","DLGAP2 is a PSD protein regulated by FMRP and by Ca2+/calmodulin-dependent protein kinase II, suggesting its involvement in activity-induced regulation of synaptic properties. Two SNPs in DLGAP2 have been associated with volumetric changes in the orbitofrontal cortex white matter in OCD pediatric  patients\n","15207911; 19896464; 19640847; 23154099","x","-","-","-","-","Yes","Yes","Yes","-","MED","Postnatal-biased","Yes","DUP_disr","yes","DLGAP2|0.155","Not_SegDup","Physical interaction with SHANK2 gene (Phelan-McDermis syndr - #606232), SHANK3 gene (SCZ - #613950) and with NLGN4X gene (ASD #300495)","n/a",1,0,0,1,1,1]
[33,"5245_3|3:117285007-117477191","LSAMP","Neuronal surface glycoprotein found in cortical and subcortical regions of the limbic system.","-","-","-","Yes","Yes","-","x","x","-","-","-","LAMP  has a critical role in hippocampal-dependent synaptic physiology and behavior. Associations between LSAMP gene polymorphisms and major depressive disorder and panic disorder","22892717; 18199495; 20385375\n","Mice homozygous for mutations in this gene are hyperresponsive to novel environments. Mice homozygous for another knock-out allele exhibit reduced barbering, whisker trimming, anxiety, dominance, and aggression.","-","LSAMP","-","LSAMP:growth/size phenotype;behavior/neurological phenotype","Yes","Yes","-","-","HI","Unbiased","Yes","DEL_disr","yes","LSAMP|0.631","Not_SegDup","Physical interaction with SNCA gene (AD Parkinson disease - #605543, Levy body Dementia - #127750) and PRNP gene (Gerstmann-Straussler disease - #137440)","n/a",1,0,0,1,1,1]
[34,"6246_4|9:9399606-9631169","PTPRD","Member of the protein tyrosine phosphatase family. ","-","-","-","Yes","-","-","x","x","-","-","-","PTPdelta-NGL-3 interaction instructs  presynaptic differentiation in a unidirectional manner. Rare structural variants in PTPRD have been identified in restless legs syndrome and in attention-deficit hyperactivity disorder","19546859; 20139422; 18660810","Homozygotes for a targeted null mutation exhibit impaired learning of spatial tasks, enhanced long-term potentiation at hippocampal synapses, and high mortality associated with reduced food intake.","-","PTPRD","-","PTPRD:nervous system phenotype;muscle phenotype;adipose tissue phenotype;growth/size phenotype;behavior/neurological phenotype;respiratory system phenotype;skeleton phenotype;mortality/aging;integument phenotype","Yes","Yes","Yes","-","MED","Unbiased","Yes","DEL_disr","yes","PTPRD|0.838","Not_SegDup","x","n/a",0,0,0,1,1,1]
[35,"6259_3|9:139523184-140273252","CACNA1B","Pore-forming subunit of an N-type voltage-dependent Ca2+ channel, which controls neurotransmitter release from neurons","-","-","-","Yes","-","-","x","x","-","-","-","N-type calcium channels are regulated by Cdk5 to affect presynaptic function and that the compartimentalization of these channels (along with GABA(B1a) receptor) is required for presynaptic inhibition at hippocampal synapses. Other studies showed that Ca(2+) modulates various neurophysiological functions  in the central nervous system, such as locomotor activity, long-term memory, and sensorimotor gating through the alpha(1B) subunit of the N-type calcium channels. GWAS and CNVs encompassing CACNA1B have been identified in SCZ patients.","19065143; 20489179; 22920258; 21880914; 22066001; 20615089; 19963013\n\n\n\n","Mice deficient in this gene exhibit defects in nociception, memory and learning. They also exhibit hyperactive and hyperaggressive behaviors as well as defects in the the sleep-wake cycle","-","CACNA1B","-","CACNA1B:nervous system phenotype;homeostasis/metabolism phenotype;hearing/vestibular/ear phenotype;growth/size phenotype;endocrine/exocrine gland phenotype;cardiovascular system phenotype;behavior/neurological phenotype;mortality/aging;integument phenotype","-","-","Yes","-","MED","Unbiased","-","NAHR, DEL-9q34","yes","CACNA1B|0.352","SegDup","Physical interaction and Patwhay with CASK (FG syndr - #300422, ID and microcephaly with pontine and cerebellar hypoplasia - #300749, ID with or without nystagmus - #300422)","n/a",1,1,0,1,1,1]
[36,"8463_202|17:52774693-52887687","MSI2","RNA-binding proteins expressed in the CNS","-","-","-","Yes","-","Yes","x","x","-","-","-","MSI2 has been shown to regulate neural precursor cells and subpopulations of neurons in mammalian CNS.  This is achieved through HuR-mediated binding of MSI2 to the conserved terminal loop of pri-miR-7. Dense-map genome scan for dyslexia showed highedt Lod Score for MSI2.\n\n","12407178; 23307866; 11588182; 23190410\n","Mice homozygous for a gene trapped allele exhibit lethality, decreased body size, and decreased hematopoietic stem cells.","-","-","-","MSI2:tumorigenesis;growth/size phenotype;immune system phenotype;reproductive system phenotype;hematopoietic system phenotype;mortality/aging","-","-","-","-","MED","Unbiased","Yes","DEL_disr","yes","MSI2|0.206","Not_SegDup","Predicted strong interaction  with CAMTA1 gene (Non progressive cerebellar ataxia with ID -  #614756)","n/a",0,0,0,0,0,0]
[37,"18172_302|10:34963905-35536952","PARD3","Member of the PARD protein family. PARD family members affect asymmetrical cell division and direct polarized cell growth. ","-","-","-","Yes","-","Yes","x","x","-","-","-"," PAR-3 plays a key role in controlling cell proliferation, polarity, and tissue organization during CNS development. Siah regulation of Pard3A controls neuronal cell adhesion during germinal zone exit. Also, an association study showed that certain genotype frequencies of the PARD3 SNPs were significantly associated with schizophrenia.","16474385; 20619750; 21109632 ; 16474385; 22969987","Mice homozygous for a null allele exhibit embryonic lethality at E12.5 associated with growth retardation, abnormal heart development, and abnormal epicardial cell development.","-","PARD3","-","-","-","-","-","Yes","MED","Unbiased","Yes","DUP_disr","yes","PARD3|0.478","Not_SegDup","Physical interaction with PLCB1 gene (Early Infantile Epileptic Encephalopathy - #613722)","n/a",1,1,0,0,1,1]
[38,"6164_3|6:160023074-160081618","SOD2","Member of the iron/manganese superoxide dismutase family","-","-","-","Yes","-","Yes","Microvascular complications of diabetes","612634","-","-","-","SOD2 deficient mice strains present with neurodegeneration and early lethality. Simmilar studies were replicated with Drosophila. The study of postmortem BA21 temporal cortex of ASD patients revealed decreased mitochondrial antioxidant enzyme SOD2 and greater oxidative DNA damage. \n\n","23333625; 22516022; 22950046","Mutations affect mitochondrial function. Null homozygotes die early with cardiomyopathy, tissue lipid accumulation, neurodegeneration, motor problems and/or metabolic acidosis depending on strain background. Heterozygotes show mitochondria and apoptosis defects with age.","-","SOD2","-","SOD2:pigmentation phenotype;tumorigenesis;nervous system phenotype;renal/urinary system phenotype;muscle phenotype;liver/biliary system phenotype;adipose tissue phenotype;homeostasis/metabolism phenotype;hearing/vestibular/ear phenotype;growth/size phenotype;cellular phenotype;cardiovascular system phenotype;behavior/neurological phenotype;immune system phenotype;reproductive system phenotype;vision/eye phenotype;other phenotype;hematopoietic system phenotype;mortality/aging;integument phenotype","-","-","-","-","HI","Postnatal-biased","Yes","DUP_disr","yes","SOD2|0.656","Not_SegDup","Physical interaction with MYH8 gene (Carney complex variant - #608837; Trismus-pseudocamptodactyly syndr -#158300 )","n/a",1,1,1,0,1,1]
[39,"8500_201|8:74692898-74967280","STAU2","Member of the family of dsRNA-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles.","-","-","-","Yes","-","-","x","x","-","-","-","Staufen2 is a mRNA-binding protein expressed in the cell bodies and cellular processes of different brain cells. It regulates the balance of stem cell maintenance versus differentiation. It has also been shown that  STAU2 and FMRP proteins are good candidates to subserve RNA transport in sensory neurons, linking somal transcriptional events to axonal translation. STAU2 also regulates mGluR long-term depression in hippocampal neuron. ","22902294; 20510018; 17587311; 21508097; 16809002\n","x","-","-","-","-","-","-","-","-","HI","Unbiased","Yes","DEL_disr","yes","STAU2|0.477","Not_SegDup","x","n/a",0,0,0,0,1,1]
[40,"6248_3|6:86352577-86376159","SNX14","Member of the sorting nexin family, which are involved in intracellular trafficking. ","-","-","-","Yes","-","-","x","x","-","-","-","SNX14 has been proposed as a gene responsible for ID in the context of 6q14.1-q14.3 and 6q12.1-q14.1 microdeletions.\n",22561202,"x","-","-","-","-","-","-","-","-","MED","Unbiased","Yes","DEL_disr","yes","SNX14|0.136","Not_SegDup","x","n/a",0,0,0,0,0,0]
[41,"3174_3|3:19921061-20096832","KAT2B","The protein encoded by this gene associates with p300/CBP, which are involved in signalling of cell growth and/or differentiation","-","-","-","Yes","-","-","x","x","-","-","-","CBP/p300 and KAT2B are key players in neuronal outgrowth, acetylate histone H3 at K9-14 and the transcription factor p53, thereby initiating a pro-neuronal outgrowth transcriptional program. It also has a role in the regulation of the cell cycle (specificaly at the G2/M checkppoint)","20094059; 20505338\n","Mice homozygous for a null allele exhibit no abnormal phenotype.","-","-","-","KAT2B:normal phenotype;growth/size phenotype;embryogenesis phenotype;mortality/aging","-","-","-","-","MED","Postnatal-biased","Yes","DEL_disr","yes","-","Not_SegDup","Physical interactions & Pathway with CREBBP (Rubinstein-Taybi syndr - #180849)","n/a",0,0,1,0,0,1]
[42,"3477_3|18:30280260-30327512","DTNA","Component of the dystrophin-associated protein complex, which consists of dystrophin and several integral and peripheral membrane proteins","-","-","-","Yes","-","Yes","Familial Isolated Noncompaction of Left Ventricular Myocardium","#604169","-","-","-","Studies in zebrafish showed that  DTNA is expressed widely in the brain with particularly strong expression in the hypothalamus and the telencephalon. Dystrophin complex can function as a scaffold for signaling proteins\n","18042440; 12138249","Homozygous targeted mutants exhibit skeletal and cardiac myopathies. Neuromuscular junctions appear to form normally, but their postnatal maturation is compromised","-","DTNA","-","DTNA:nervous system phenotype;muscle phenotype;limbs/digits/tail phenotype;growth/size phenotype;cardiovascular system phenotype;behavior/neurological phenotype;skeleton phenotype;mortality/aging","Yes","-","Yes","-","MED","Postnatal-biased","Yes","DEL_disr","yes","DTNA|0.904","Not_SegDup","Physical interction with DMD gene (Duchenne Muscular Dystrophy - #310200)","x",1,0,0,1,1,1]
[43,"14393_5020|10:74801551-75278951","CAMK2G","One of the four subunits of a serine/threonine protein kinase family, and to the Ca2+/calmodulin-dependent protein kinase subfamily","-","-","-","Yes","-","-","x","x","-","-","-","Pathway analysis of genetic markers associated with a functional MRI during a commonly applied experiment based on a face matching task implicated polymorphisms in CAMK2G and CAMK2D in responsive pathways. CAMK2G has also been associated with memory performance and hippocampal activity in humans.","23274185; 16537520","Mice homozygous for a knock-out allele exhibit female infertility and decreased sensitivity of macrophages to ER stress-induced apoptosis.","-","-","-","-","Yes","Yes","-","-","HI","Unbiased","Yes","DEL_disr","yes","CAMK2G|0.481","Not_SegDup","Physical interaction with SPR gene (Dystonia DOPA-Responsive - #612716), Patwhay with MAPT gene (Frontotemporal Dementia - #600274; Pick disease - #172700; Progressive Supranuclear Palsy - #601104)","x",1,1,0,0,1,1]
[44,"4260_1|2:119603876-119882278","DBI","Diazepam binding inhibitor, a protein that modulates signal transduction at type A gamma-aminobutyric acid receptors in brain synapses","-","-","-","Yes","-","Yes","x","x","-","-","-","CNVs encompassing DBI in ASD patients. Also, multiple missense mutations in the DBI gene were identified in schizophrenia patients.\n","22543975; 14755437\n","Mice homozygous for a knock-out allele exhibit abnormal fur and skin morphology at P16 and impaired metabolic changes at weaning with reduced growth and hepatic cholesterol synthesis","-","DBI","-","DBI:liver/biliary system phenotype;homeostasis/metabolism phenotype;growth/size phenotype;behavior/neurological phenotype;mortality/aging;integument phenotype","-","-","-","-","HI","Unbiased","-","DUP","-","DBI|0.011","Not_SegDup","x","n/a",0,0,0,0,1,1]
[45,"20089_1391001|16:29502984-30107306; 2204_1|16:29466569-30147029; 4030_1|16:29554843-30107306; 5068_3|16:29502984-30127026; 5262_4|16:29502984-30210849; 5359_4|16:29554843-30195224","TAOK2","Ser/Thr protein kinase  involved in many different processes, including, cell signaling, microtubule organization and stability, and apoptosis. ","-","-","-","Yes","-","-","x","x","-","-","-","TAOK2 affects basal dendrite formation in the neocortex ",22683681,"Mice homozygous for a transgenic gene disruption exhibit decreased body size.","-","-","-","-","Yes","Yes","Yes","Yes","HI","Unbiased","-","NAHR, DEL/DUP-16p11.2","yes","TAOK2|0.599","SegDup","Pathway interaction with ATM gene (Ataxia Telangiectasia - #208900)","n/a",1,1,1,1,1,1]
[46,"6240_4|11:126633939-132060374","ARHGAP32","Neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase activity","-","-","-","Yes","-","-","x","x","-","-","-","Genetic variation in ARHGAP32 increases susceptibility for schizophrenia and also for schizotypal personality traits.","22530067\n","Mice homozygous for a null mutation are fertile but display abnormal neurite growth.","-","-","-","ARHGAP32:nervous system phenotype;reproductive system phenotype","Yes, expressed primarily at neurite growth cones, and at the post synaptic membranes; miR-132 is enriched in neuronal cells and targets the mRNA from this gene for degradation","-","Yes","-","HI","Unbiased","-","DEL","-","-","Not_SegDup","x","n/a",1,0,0,1,1,1]
[47,"8588_201|3:195971510-197675831","TNK2","Tyrosine kinase, non-receptor (or ACK1)","-","-","-","Yes","-","-","x","x","-","-","-","TNK2 is up-regulated during development and  it is expressed in proliferative areas and in migratory pathways in the developing brain of mice.    It has been implicated in cell spreading and migration, cell survival, cell growth and proliferation; may be involved both in adult synaptic function and plasticity and in brain development.","16750431; 16052498\n","x","-","-","-","-","-","-","Yes","-","HI","Postnatal-biased","-","DEL","yes","TNK2|0.369","Not_SegDup","Interacts with SNX9","Interacts with SNX9",0,0,0,1,1,1]
[48,"6240_4|11:126633939-132060374","ETS1","ETS family of transcription factors","-","-","-","Yes","-","Yes","x","x","-","-","-","An association study has linked ETS1 to schizophrenia. ","23301017\n\n","Homozygotes for targeted null mutations exhibit reduced numbers of peripheral CD8+ T cells, impaired TCR-mediated activation of both CD4+ and CD8+ T cells, increased numbers of IgM-secreting plasma cells, and severely impaired NK cell development.","-","-","-","ETS1:homeostasis/metabolism phenotype;growth/size phenotype;embryogenesis phenotype;cellular phenotype;cardiovascular system phenotype;immune system phenotype;hematopoietic system phenotype;mortality/aging","-","-","-","-","MED","Unbiased","-","DEL","yes","ETS1|0.951","Not_SegDup","x","x",1,0,1,0,1,1]
[49,"8534_201|10:45633089-51564756","MAPK8","This kinase is involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway ","-","-","-","Yes","-","Yes","x","x","-","-","-","MAPK8 inhibits GluR1 expression and GluR1-mediated calcium influx through phosphorylation and stabilization of Hes-1 (which is a mammalian transcription repressor that regulates neuronal differentiation and development)",22302822,"Mice homozygous for a knock-out allele exhibit abnormal T cell differentiation and proliferation, cardiac morphology and physiology, and chemically-induced tumorigenesis. Mice homozygous for another knock-out allele exhibit abnormal glucose homeostasis and T cell physiology.","-","-","-","MAPK8:tumorigenesis;nervous system phenotype;renal/urinary system phenotype;muscle phenotype;liver/biliary system phenotype;adipose tissue phenotype;homeostasis/metabolism phenotype;growth/size phenotype;embryogenesis phenotype;digestive/alimentary phenotype;craniofacial phenotype;cellular phenotype;cardiovascular system phenotype;behavior/neurological phenotype;immune system phenotype;respiratory system phenotype;reproductive system phenotype;vision/eye phenotype;hematopoietic system phenotype;mortality/aging;integument phenotype","-","-","-","-","HI","Prenatal-biased","-","NAHR, DEL-10q","yes","MAPK8|0.964","SegDup","x","Association with TP53",1,1,1,0,1,1]
[50,"8677_201|4:94659049-95289667","ATOH1","proneural basic helix-loop-helix (BHLH) transcription factor","-","-","-","Yes","Yes","-","x","x","-","-","-","ATOH1 is involved in differentiation of neurons, secretory cells in the gut, and mechanoreceptors including auditory hair cells. Mice lacking the Atoh1 lack multiple neurons of the proprioceptive and arousal systems and die shortly after birth from an apparent inability to initiate respiration ","19864427; 19914183","Homozygotes for targeted null mutations exhibit a decreased cerebellum without folia, and lack cerebellar granule neurons, inner-ear hair cells, D1 interneurons, and goblet, enteroendocrine, and Paneth cells. Mutants fail to breathe properly and die at birth. ","-","ATOH1","-","-","-","-","-","-","LOW","NA","-","DUP","-","ATOH1|0.757","Not_SegDup","x","x",1,1,1,0,1,1]
[51,"8404_201|6:169136788-170761395","TBP","TATA box binding protein (Initiation of transcription by RNA polymerase II)","-","-","-","Yes","Yes","Yes","SCA17, Late onset Parkinson - caused by expansion of a CAG repeat in the coding region","#607136\n#168600","TBP","-","-","TBP as a candidate gene for mental retardation in patients with subtelomeric 6q deletions","16773126; 21950800\n","Mice homozygous for one null allele exhibit embryonic lethality caused by hemorrhaging and clotting in the placenta and surviving embryos die prior to weaning. Mice homozygous for another null allele undergo growth arrest after hatching and apoptosis.","-","-","-","-","-","-","-","-","MED","Unbiased","-","DEL","yes","TBP|1","Not_SegDup","x","x",0,0,0,0,1,1]
[52,"17015_1|22:17257787-19795780; 3183_7|22:17241748-19819918; 4271_1|22:17257787-19795780; 8627_201|22:17257787-19793730","CRKL","Kinase that activates the RAS and JUN kinase signaling pathways and transforms fibroblasts in a RAS-dependent fashion.","-","-","-","Yes","-","Yes","x","x","-","-","-","Study in mice embryo let to the identification of CrkL-SH3 binding proteins as having a significant role in Reelin signaling during brain development, namely in dendritogenesis.","21879738; 18477607","Mice homozygous for a null allele exhibit fetal lethality with abnormal heart, craniofacial, and brain morphology","-","CRKL","-","CRKL:tumorigenesis;nervous system phenotype;liver/biliary system phenotype;limbs/digits/tail phenotype;hearing/vestibular/ear phenotype;growth/size phenotype;endocrine/exocrine gland phenotype;embryogenesis phenotype;craniofacial phenotype;cardiovascular system phenotype;immune system phenotype;skeleton phenotype;vision/eye phenotype;hematopoietic system phenotype;mortality/aging;integument phenotype","Yes","-","-","-","HI","Unbiased","-","NAHR, DEL/DUP-22q","yes","CRKL|0.942","SegDup","CoExpression & Predicted interaction with HSPD1 gene (AD SPG13 - #605280 &  AR Hypomielinating Leukodystrophy - #612233)","n/a",1,0,1,1,1,1]
[53,"13123_1403|9:98998-3682923","RFX3","Transcription factor with highest expression in the brain, intestine, and testis ","-","-","-","Yes","-","Yes","x","x","-","-","-","The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development","22479201; 22415835","Homozygous null mice display embryonic and perinatal lethality, impaired development of cilia on the embryonic node, abnormal left-right patterning, meso- and dextrocardia, and situs inversus in surviving adults","-","-","-","RFX3:normal phenotype;growth/size phenotype;embryogenesis phenotype;cardiovascular system phenotype;mortality/aging","-","-","-","-","MED","Prenatal-biased","-","DEL","yes","RFX3|0.934","Not_SegDup","Physical interaction, CoExpression and Colocalization with IRF6 Popliteal Pterygium syndr -  #119500 & Van der Woude syndr - #119300)","n/a",0,1,1,0,0,1]
[54,"3174_3|3:19921061-20096832","RAB5A","Member of the RAS oncogene family","-","-","-","Yes","-","-","x","x","-","-","-","Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis",20926670,"x","-","-","-","-","Yes","-","-","-","HI","Unbiased","-","DEL","yes","RAB5A|0.726","Not_SegDup","Physical interactions & Pathway with GDI1 gene (ID xl - #300849)","n/a",1,1,0,1,1,1]
[55,"14393_5020|10:74801551-75278951","PPP3CB","Protein phosphatase; it is especially abundant in brain where it constitutes 1% of total protein.","-","-","-","Yes","-","-","x","x","-","-","-","ANXA7, PPP3CB, DNAJC9, and ZMYND17 genes at chromosome 10q22 associated with the subgroup of schizophrenia with deficits in attention and executive function\n",21531385,"Homozygous null mice have small hearts and thymi, and reduced body weight. Cardiac function is normal, but mice lack a cardiac hypertrophic response to pressure overload, angiotensin II, or isopreteronol. Thymi are hypoplastic, with abnormal T cell development and reduced numbers of T cells.","-","-","-","PPP3CB:muscle phenotype;homeostasis/metabolism phenotype;growth/size phenotype;cardiovascular system phenotype;behavior/neurological phenotype;immune system phenotype;hematopoietic system phenotype","Yes","Yes","-","-","HI","Unbiased","-","DEL","yes","PPP3CB|0.684","Not_SegDup","Physical interaction with MLH1 gene (Lynch syndr - #120435)","n/a",1,1,1,1,1,1]
[56,"17035_1|15:20274130-26120360; 20069_1328001|15:20203578-26209270; 20187_1464001|15:18811937-26209270; 8430_204|15:20301669-20777695; 8630_201|15:19800798-26209270; 9759_201|15:19777876-20778963","CYFIP1","Interacts with FMRP; maps to nonimprinted PWS/AS region","-","-","-","Yes","-","Yes","x","x","-","-","-","Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice. CNVs encompassing CYFIP1 have also been identified in SCZ patients","22900020; 20298200","Mutations at this locus result in embryonic lethality before the turning stage in homozygotes","-","CYFIP1","-","CYFIP1:nervous system phenotype;embryogenesis phenotype;mortality/aging","Yes","Yes","-","-","MED","Unbiased","-","NAHR, DEL/DUP-15q11.2","-","CYFIP1|0.153","SegDup","Physical interaction and Predicted with FMR1 (Fragile X - #300624) and NIPA2 (NonImprinted PWS/AS region)","n/a",1,1,1,0,1,1]
[57,"6130_4|22:47996161-49512530; 2072_1|22:45159185-49582267","MAPK12","Signal transducer during differentiation of myoblasts to myotubes","-","-","-","Yes","-","-","x","x","-","-","-","Braf and Erk3 are coexpressed in the hippocampus ","17120291; 8954940\n","Homozygous null mice are viable and fertile with no obvious abnormalities. Mice homozygous for a conditional allele activated in muscle cell exhibit decreased endurance exercise-induced mitochondrial biogenesis and angiogenesis.","-","-","-","MAPK12:normal phenotype;muscle phenotype;cellular phenotype;cardiovascular system phenotype","-","-","-","-","MED","Unbiased","-","NAHR, DEL-22q-SHANK3","yes","MAPK12|0.471","SegDup","x","x",1,1,1,0,1,1]
[58,"20089_1391001|16:29502984-30107306; 2204_1|16:29466569-30147029; 4030_1|16:29554843-30107306; 5068_3|16:29502984-30127026; 5262_4|16:29502984-30210849; 5359_4|16:29554843-30195224","MAPK3","Mitogen-activated protein kinases (MAPKs) that participates in cell cycle progression","-","-","-","Yes","-","Yes","x","x","-","-","-","Upregulation of Ras/Raf/ERK1/2 signaling impairs cultured neuronal cell migration, neurogenesis, synapse formation, and dendritic spine development  and has been demonstrated in the brain of autistic subjects","21848643; 22555958; 22745486","Mice homozygous for a targeted null mutation are hyperactive with impaired T cell maturation and proliferation. ","-","MAPK3","-","MAPK3:nervous system phenotype;liver/biliary system phenotype;homeostasis/metabolism phenotype;growth/size phenotype;cellular phenotype;cardiovascular system phenotype;behavior/neurological phenotype;immune system phenotype;respiratory system phenotype;hematopoietic system phenotype;mortality/aging","Yes","Yes","-","-","HI","Postnatal-biased","-","NAHR, DEL/DUP-16p11.2","-","MAPK3|0.976","SegDup","Multiple interactions (Co-expresssion, Physical interaction, Pathway) with SOS1, RAF1, BRAF (Rasopathies)","n/a",1,1,0,1,1,1]
[59,"2072_1|22:45159185-49582267; 6130_4|22:47996161-49512530","MAPK11","This kinase is activated by MAP kinase kinases, preferably by MKK6, in response to proinflammatory cytokines and environmental stress.","-","-","-","Yes","Yes","-","x","x","-","-","-","MAPK11 controls gap junction closure in astrocytes. MAPK11 affords cytoprotection against oxidative stress-induced astrocyte apoptosis via induction of αB-crystallin and its anti-apoptotic function","21777656; 15048855\n","Mice homozygous for a knock-out allele exhibit a normal phenotype.","-","-","-","MAPK11:normal phenotype;muscle phenotype;homeostasis/metabolism phenotype;digestive/alimentary phenotype;cellular phenotype;cardiovascular system phenotype;immune system phenotype;skeleton phenotype;hematopoietic system phenotype","-","-","-","-","HI","Unbiased","-","NAHR, DEL-22q-SHANK3","yes","MAPK11|0.594","SegDup","x","Association with HSPB1 gene (#606595 - CMT2F, #608634 - HMN2B)",1,1,0,0,1,1]
[60,"5444_3|17:76953064-77782267","RAC3","Rac proteins are members of the Rho family of GTPases involved in the regulation of actin dynamics","-","-","-","Yes","-","-","x","-","-","-","-","In vitro overexpression of avian Rac3 specifically potentiates neuritogenesis and branching from cultured avian retinal neurons; Rac3 KO mice motor coordination and motor learning on the rotarod was superior to that of their wild-type littermates; Other studies showed  reduced behavioral flexibility to novel situations.","17889944; 15964829; 9700168 ","x","-","-","-","-","-","-","-","-","HI","Prenatal-biased","-","DUP","-","RAC3|0.928","Not_SegDup","x","x",1,1,0,0,1,1]
[61,"6321_3|8:65354366-66254869","BHLHE22","Transcription factor that regulates cell fate determination, proliferation, and differentiation; exclusively expressed in the CNS and retina. ","-","-","-","Yes","-","Yes","x","x","-","-","-","Bhlhe22 and Prdm8 form a repressor complex involved in neuronal circuit assembly. Bhlhe22 has been shown to have a role on the regulation of spinal interneuron development and on the differentianton of layers II-V of the developing neocortex ","22284184; 21750031; 18957218","Mice homozygous for a null mutation are slow to gain weight, develop skin lesions, have reduced numbers of specific subtypes of amacrine and cone bipolar cells, and exhibit abnormal innervation of the corticospinal tract.","-","BHLHE22","-","BHLHE22:nervous system phenotype;growth/size phenotype;behavior/neurological phenotype;vision/eye phenotype;integument phenotype","-","-","-","-","HI","Prenatal-biased","-","DEL","-","-","Not_SegDup","x","n/a",0,0,0,0,1,1]
[62,"16040_1571029001|15:28450423-30303265","KLF13","KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains","-","-","-","Yes","-","-","x","x","-","-","-","KLF13 has been implicated in SCZ in the context of  15q13-q14 CNVs. Also, homozygous deletion of chromosome 15q13.3 including CHRNA7 causes severe mental retardation, seizures, muscular hypotonia, and the loss of KLF13 and TRPM1 potentially cause macrocytosis and congenital retinal dysfunction in siblings","21970977; 21596161","Mice homozygous for a disruption in this gene are grossly normal. Prolonged thymocyte survival leads to an enlarged thymus and spleen. Mice homozygous for a different allele exhibit splenomegaly and abnormal erythropoiesis.","-","-","-","KLF13:immune system phenotype;hematopoietic system phenotype","-","-","-","-","MED","Unbiased","-","NAHR, DEL-15q13","yes","KLF13|0.894","SegDup","Physical interaction with GATA4 gene and GATA6 gene (Conotruncal defects)","n/a",0,0,1,0,1,1]
[63,"8446_201|7:72344426-73782113; 4158_1|7:72056621-72795997","BAZ1B","This gene encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription.","-","-","-","Yes","-","Yes","x","x","-","-","-","BAZ1B is still a good candidate for the facial and neurodevelopmental\nfeatures of WBS patients; BAZ1B might have a role in transcription, repair and replicaiton","2375644; 21326359","Mice homozygous for a null allele exhibit postnatal lethality by P2, small size at birth, impaired double strand DNA repair, and heart defects. Mice heterozygous for a null allele exhibit hypercalcemia and heart defects. Mice homozygous for an ENU mutation exhibit craniofacial and skeletal defects.","-","-","-","BAZ1B:muscle phenotype;homeostasis/metabolism phenotype;growth/size phenotype;embryogenesis phenotype;craniofacial phenotype;cellular phenotype;cardiovascular system phenotype;reproductive system phenotype;skeleton phenotype;mortality/aging","-","-","-","-","HI","Prenatal-biased","-","NAHR, DEL/DUP-7q","yes","BAZ1B|0.403","SegDup","Physical Interaction, CoExpression, and Pathway with SMARCA4 gene (ID dom - #614609) & Physical interactions and Patwhay with ARID1A gene (ID dom - #614607)","n/a",0,0,1,0,1,1]
[64,"8500_201|8:74692898-74967280","UBE2W","Ubiquinates the Fanconi anemia complementation group proteins and may be important in the repair of DNA damage","-","-","-","Yes","-","Yes","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","MED","Unbiased","-","DEL","yes","UBE2W|0.544","Not_SegDup","x","Association with FANCL & FANCD2 genes (Fanconi Anemia - #614083 and #227646)",0,0,0,0,0,0]
[65,"6358_6|19:4548413-5287389","UHRF1","It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression ","-","-","-","Yes","-","Yes","x","x","-","-","-","UHRF1 has been proposed to be a gene with significant role in long-term memory",20331892,"Mice homozygous for disruption of this marker die early in gestation showing growth retardation and various malformations.","-","UHRF1","-","UHRF1:nervous system phenotype;growth/size phenotype;embryogenesis phenotype;craniofacial phenotype;cellular phenotype;skeleton phenotype;mortality/aging","-","-","-","-","LOW","Prenatal-biased","-","DEL","-","UHRF1|0.195","Not_SegDup","Physical interaction and CoExpression with DNMT3B gene (Immunodeficiency-Centromeric Instability-Facial Anomalies syndr - #242860 )","n/a",0,0,0,0,1,1]
[66,"2211_1|17:17169258-20101517","MAPK7","Kinase specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5).","-","-","-","Yes","-","Yes","x","x","-","-","-","little information","x","Homozygous inactivation of this gene leads to embryonic growth retardation and midgestational lethality due to multiple developmental anomalies and vascular remodelling, cardiac development, and placental defects.","-","-","-","MAPK7:normal phenotype;nervous system phenotype;muscle phenotype;homeostasis/metabolism phenotype;growth/size phenotype;embryogenesis phenotype;digestive/alimentary phenotype;craniofacial phenotype;cellular phenotype;cardiovascular system phenotype;behavior/neurological phenotype;mortality/aging;integument phenotype","-","-","-","Yes","MED","Prenatal-biased","-","NAHR, DEL-17q-RAI1","-","MAPK7|0.626","SegDup","Physical interactions & CoExpresion with GJA1 (OculoDentoDigital syndr - #164200)","n/a",1,0,1,1,1,1]
[67,"4272_1|14:63824114-65347410","MAX","Member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors.","-","-","-","Yes","-","Yes","Hereditary Paraganglioma-Pheochromocytoma syndr","#171300","-","-","-","little information","x","Mice homozygous for a targeted mutation die between E5.5 and 6.5 displaying a generalized developmental arrest of both embryonic and extraembryonic tissues. These defects are not associated with inappropriate apoptosis, but rather with a failure of cells to divide.","-","-","-","MAX:growth/size phenotype;embryogenesis phenotype;mortality/aging","-","-","-","-","HI","Unbiased","-","DEL","-","MAX|0.222","Not_SegDup","Physical interaction with MYCN gene (Feingold syndr - #164280)","n/a",1,0,1,0,0,1]
[68,"5272_3|12:98445422-98540678","ANKS1B","Interacts with amyloid beta protein precursor and may have a role in normal brain development and in the pathogenesis of Alzheimer's disease.","-","-","-","Yes","-","Yes","x","x","-","-","-","little information","x","x","-","-","-","-","Yes","Yes","-","-","MED","Unbiased","-","DEL","-","ANKS1B|0.176","Not_SegDup","Phisical interaction with LRP2 gene (Donnai-Barrow syndr - #222448)","n/a",1,0,0,0,1,1]
[69,"6402_3|4:98781694-99627129","RAP1GDS1","Stimulatory GDP/GTP exchange protein with GTPase activity","-","-","-","Yes","-","Yes","x","x","-","-","-","little information","x","x","-","-","-","-","Yes","Yes","-","-","HI","Unbiased","-","DUP","-","RAP1GDS1|0.195","Not_SegDup","Physical interaction with KRAS gene (CardioFacioCutaneous syndr - #115150) and with NRAS gene (Noonan syndr - #613224)","n/a",0,0,0,0,1,1]
[70,"8587_210|3:139760896-140127703","PIK3CB","Catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils","-","-","-","Yes","-","Yes","x","x","-","-","-","little information","x","Mice homozygous for a knock-out allele exhibit 30% fetal lethality, decreased size at birth and postnatally, abnormal glucose homeostasis, and dyslipidemia. Mice homozygous for a different knock-out allele die prior to E8.5","-","-","-","PIK3CB:tumorigenesis;homeostasis/metabolism phenotype;growth/size phenotype;endocrine/exocrine gland phenotype;embryogenesis phenotype;cellular phenotype;cardiovascular system phenotype;hematopoietic system phenotype;mortality/aging","-","-","-","-","MED","Unbiased","-","DUP","-","PIK3CB|0.996","Not_SegDup","x","Association with PTPN11 gene (Noonan syndr - #163950) and with PTEN gene (Cowden - #158350 & Bannayan-Riley-Ruvalcaba syndr - #153480)",1,1,1,0,1,1]
[71,"1050_3|14:20279711-20345174","RNASE6","Ribonuclease","-","-","-","Yes","-","Yes","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","MED","Unbiased","-","DUP","-","RNASE6|0.4","Not_SegDup","x","CoExpression with TYROBP gene (Polycystic Lipomembranous Osteodysplasia with Sclerosing Leukoencephalopathy - #221770)",0,0,0,0,0,0]
[72,"6053_3|12:54218922-58779615","CDK4","Ser/Thr protein kinase involved in the cell cycle","-","-","-","Yes","-","-","Susceptibility to Cutaneous Malignant Melanoma","609048","-","-","-","FMRP regulates proliferation and differentiation of adult neural stem/progenitor (aNPC) cells thorugh the regulation of CDK4 and GSK3beta. ",20386739,"Homozygous null mutants have small size, insulin-deficient diabetes, sterility in females; near-sterility in males and impaired prolactin secretion due to hypoplastic pituitary development. Locomotor and endocrine gland defects are seen with some alleles","-","CDK4","-","CDK4:tumorigenesis;nervous system phenotype;renal/urinary system phenotype;muscle phenotype;liver/biliary system phenotype;homeostasis/metabolism phenotype;growth/size phenotype;endocrine/exocrine gland phenotype;embryogenesis phenotype;digestive/alimentary phenotype;cellular phenotype;cardiovascular system phenotype;behavior/neurological phenotype;immune system phenotype;reproductive system phenotype;vision/eye phenotype;hematopoietic system phenotype;mortality/aging;integument phenotype","-","-","-","-","HI","Prenatal-biased","-","DUP","-","CDK4|1","Not_SegDup","x","n/a",0,1,1,0,1,1]
[73,"14331_4450|18:72085223-73670156","GALR1","The neuropeptide galanin elicits a range of biological effects. It is widely expressed in the brain and spinal cord, small intestine and heart.","-","-","-","Yes","-","-","x","x","-","-","-","Impairment of memory consolidation by galanin correlates with in vivo inhibition of both LTP and CREB phosphorylation \n\n","19531380; 23112793; 22302430","Homozygous mutation of this gene does not appear to result in a phenotype.","-","-","-","GALR1:normal phenotype;behavior/neurological phenotype","-","-","-","-","LOW","Postnatal-biased","-","DEL","-","GALR1|0.077","Not_SegDup","x","n/a",0,0,0,0,0,0]
[74,"8446_201|7:72344426-73782113","LIMK1","Ser/Thr protein kinase that regulates actin polymerization. This protein stimulates axon growth and may play a role in brain development.","-","-","-","Yes","-","-","x","x","-","-","-","Tissue specific characterisation of Lim-kinase 1 expression during mouse embryogenesis\n",21167960,"Mice homozygous for disruptions in this gene display an abnormal actin cytoskeleton in neurons of the central nervous system and structural abnormalities of the dendritic spines. Long term potentiation is altered and behavioral anomalies are seen.","-","LIMK1","-","LIMK1:nervous system phenotype;behavior/neurological phenotype","-","-","-","-","HI","Unbiased","-","NAHR, DEL/DUP-7q","-","LIMK1|0.285","SegDup","x","n/a",1,1,1,0,1,1]
[75,"13135_1523|1:144838594-146308287; 16035_1571013001|1:144482933-146325557; 8635_201|1:144500467-146377870","CHD1L","DNA helicase that interacts with PAR and has a role in chromatin relaxation following DNA damage","-","-","-","Yes","-","-","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","MED","Unbiased","-","NAHR, DEL/DUP-1q21","-","CHD1L|0.147","SegDup","x","Association with HRAS gene (Costello syndr - #218040)",0,0,0,0,0,0]
[76,"20180_1704001|21:43018846-43444308","WDR4","Member of the WD repeat protein family. WD repeats facilitate formation of heterotrimeric or multiprotein complexes. ","-","-","-","Yes","-","-","x","x","-","-","-","little information","-","x","-","-","-","-","-","-","-","-","MED","Unbiased","-","DUP","-","WDR4|0.808","Not_SegDup","x","Association with NSUN2 gene (ID rec - #611091)",0,0,0,0,1,1]
[77,"1960_301|7:102699832-102798745","PMPCB","Peptidase located in the mitochondrial matrix; catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria","-","-","-","-","Yes","Yes","x","x","-","-","-","little information","x","Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E8.","-","-","-","-","-","-","-","-","HI","Unbiased","-","DEL","-","PMPCB|0.193","Not_SegDup","Physical interaction and CoExpression with FXN gene (Friedreich Ataxia - #229300)","x",0,0,0,0,0,0]
[78,"6321_3|8:65354366-66254869","CYP7B1","Member of the cytochrome P450 superfamily of enzymes. ","-","-","-","-","Yes","-","SPG5A, Congenital Bile Acid Synthesis Defect","#270800\n#613812","-","-","-","Spatiotemporal dynamics of the expression of estrogen receptors in the postnatal mouse brain",18982005,"Mice homozygous for a knock-out allele show significantly increased levels of 25- and 27-hydroxycholesterol, and reduced IgA levels. Female mice homozygous for a reporter allele display early onset of puberty and early ovarian failure.","-","-","-","CYP7B1:homeostasis/metabolism phenotype;endocrine/exocrine gland phenotype;immune system phenotype;reproductive system phenotype;integument phenotype","-","-","-","-","MED","Unbiased","-","DEL","-","CYP7B1|0.264","Not_SegDup","x","x",1,1,1,0,0,1]
[79,"8695_201|15:81728085-82623936","SH3GL3","Selectively interacts with Huntingtin; preferentially expressed in the brain and testis","-","-","-","-","Yes","-","x","x","-","-","-","SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates ","9809064; 9169142","x","-","-","-","-","Yes","-","-","-","HI","Unbiased","-","DEL","-","SH3GL3|0.074","Not_SegDup","Physical interaction and Patway with HTT gene (Huntington disease -  #143100) and Physical interaction with ATXN2 gene (SCA2 - #183090)","x",1,0,0,0,1,1]
[80,"13082_963|2:11712589-11741036","NTSR2","Member of the G protein-coupled receptor family that activates a phosphatidylinositol-Ca2+ second messenger system","-","-","-","-","Yes","-","x","x","-","-","-","Hyperactivity of the dopaminergic system in NTS1 and NTS2 null mice\n",20211191,"Homozygous null mice exhibit abnormal thermal nociception. Mice homozygous for different knock-out allele exhibit increased prepulse inhibition and decreased accoustic startle response","-","NTSR2","-","NTSR2:nervous system phenotype;hearing/vestibular/ear phenotype;behavior/neurological phenotype;integument phenotype","-","-","-","-","LOW","Postnatal-biased","-","DUP","-","NTSR2|0.123","Not_SegDup","CoExpression with MLL2 gene (Kabuki syndr - #147920)","x",1,0,0,0,1,1]
[81,"5353_3|6:33399849-33512042","CUTA","cutA divalent cation tolerance homolog","-","-","-","-","Yes","-","x","x","-","-","-","CutA divalent cation tolerance homolog (Escherichia coli) (CUTA) regulates β-cleavage of β-amyloid precursor protein through interacting with β-site APP cleaving protein 1 (BACE1) ",22351782,"x","-","-","-","-","-","-","-","-","HI","Unbiased","-","DEL","-","CUTA|0.161","Not_SegDup","x","x",0,0,0,0,0,0]
[82,"5056_4|17:34612208-34732327","STAC2","SH3 and cysteine rich domain 2","-","-","-","-","Yes","-","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","MED","Postnatal-biased","-","DUP","-","STAC2|0.213","Not_SegDup","Physical interaction with ATXN1 gene (SCA1 - #164400)","x",0,0,0,0,0,0]
[83,"5386_3|6:156785155-158489874","SYNJ2","Member of the inositol-polyphosphate 5-phosphatase family.","-","-","-","-","Yes","-","x","x","-","-","-","SYNJ2 has been associated with human cognitive abilities in the elderly",22045296,"x","-","SYNJ2","-","SYNJ2:nervous system phenotype;hearing/vestibular/ear phenotype;behavior/neurological phenotype","Yes","-","-","-","MED","Unbiased","-","DEL","-","SYNJ2|0.211","Not_SegDup","x","x",1,1,0,0,1,1]
[84,"1050_3|14:20279711-20345174","RNASE1","Pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. ","-","-","-","-","Yes","-","x","x","-","-","-","little information","x","x","-","-","-","-","Yes","-","-","-","HI","Postnatal-biased","-","DUP","-","RNASE1|0.084","Not_SegDup","x","x",0,0,0,0,0,0]
[85,"18133_302|6:69540429-73375020","SMAP1","type II membrane glycoprotein involved in the erythropoietic stimulatory activity of stromal cells","-","-","-","-","Yes","-","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","HI","Prenatal-biased","-","DUP","-","SMAP1|0.208","Not_SegDup","Co-Expression with SOS1 (Noonan syndr, 610733)\n","-",0,0,1,0,0,1]
[86,"8695_201|15:81728085-82623936","BNC1","Zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. ","-","-","-","-","Yes","-","x","x","-","-","-"," BNC1 channel is essential for the normal detection of light touch",11069180,"Mice homozygous for a null allele exhibit thinning and delayed wound healing of the corneal epithelium.","-","-","-","-","-","-","-","-","LOW","Unbiased","Yes","DEL_disr","yes","BNC1|0.197","Not_SegDup","x","x",0,0,1,0,0,1]
[87,"6356_5|1:2118508-2325536","RER1","protein receptor in the endoplasmatic reticulum receptor","-","-","-","-","Yes","-","-","-","-","-","-","RER1 regulates the assembly of the gamma-secretase complex which is involved in the production of amyloid beta-peptide, which is the principal component of amyloid plaques in the brains of patients with Alzheimer disease",17668005,"Mice heterozygous for a gene trap allele exhibit a slight reduction in the size of neuromuscular junctions and muscle fiber diameter.","RER1","-","-","RER1: nervous system phenotype;muscle phenotype","-","-","-","-","HI","Unbiased","yes","DEL","yes","RER1|0.388","Not_SegDup","Predicted interaction with MAN1B1 (autosomal recessive intellectual disability - #614202)","Association with MAN1B1 (autosomal recessive intellectual disability - #614202)",0,0,0,0,1,1]
[88,"4272_1|14:63824114-65347410","ESR2","Member of the estrogen receptors family","-","-","-","-","-","Yes","x","x","-","-","-","An association study examined 59 SNPs located in the ESR1, ESR2, APOE and COMT loci. Allele frequencies were evaluated in the schizophrenia (n=585)-control (n=615) sample and no association was found with any of the four genes.",18164902,"Mice homozygous for a knock-out allele exhibit neural, behavior, glucose homeostasis, sex-specific nociception, cardiac, and ion channel abnormalities and myeloproliferative disorders. Females are sterile/subfertile with granulosa cell defects; males show prostate hyperplasia.","-","ESR2","-","-","-","-","-","-","LOW","Prenatal-biased","Yes","DEL_disr","yes","ESR2|0.274","Not_SegDup","x","x",1,1,1,0,0,1]
[89,"6164_3|6:160023074-160081618","WTAP","Plays a role in both transcriptional and posttranscriptional regulation of certain genes","-","-","-","-","-","Yes","x","x","-","-","-","WTAP is a nuclear protein that has been associated with regulation of proliferation and apoptosis. WTAP regulates migration and invasion of glioblatoma cells.",22957919,"Mice homozygous for a mutation display lethality during embryogenesis with abnormalities appearing during gastrulation.","-","-","-","WTAP:embryogenesis phenotype;mortality/aging","-","-","-","-","HI","Prenatal-biased","Yes","DUP_disr","yes","WTAP|0.207","Not_SegDup","Physical interaction with WT1 gene (Dennis-Drash - #194080 & Frasier syndr - #136680)","Association with WT1 gene",0,0,0,0,0,0]
[90,"5056_4|17:34612208-34732327","RPL19","Ribosomes","-","-","-","-","-","Yes","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","HI","Prenatal-biased","Yes","DUP_disr","yes","RPL19|0.232","Not_SegDup","x","Association with RPL5 gene and RPL11 gene (Diamond-Blackfan anemia - #612561)",0,0,0,0,0,0]
[91,"13135_1523|1:144838594-146308287; 16035_1571013001|1:144482933-146325557; 8635_201|1:144500467-146377870","PRKAB2","Regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK has a role in the de novo biosynthesis of fatty acid and cholesterol","-","-","-","-","-","Yes","x","x","-","-","-","Certain SNPs in ORKAB2 are associated with antipsychotic-induced weight gain.",22305490,"Mice homozygous for a knock-out allele exhibit decreased exercise endurance, muscle force, muscle and liver glycogen, and skeletal muscle fiber size and increased susceptibility to diet induced obesity and hyperinsulinemia.","-","-","-","PRKAB2:muscle phenotype;liver/biliary system phenotype;homeostasis/metabolism phenotype;growth/size phenotype","-","-","-","-","MED","Prenatal-biased","-","NAHR, DEL/DUP-1q21","yes","PRKAB2|0.654","SegDup","x","Association with STK11 gene (Peutz-Jeghers - #175200) and with PRKAG2 gene (Hypertrophic Cardiomyopathy - #600858; WPW - #194200; Glycogen storage disease of the heart - #261740)",0,0,1,0,0,1]
[92,"6358_6|19:4548413-5287389","TICAM1","Adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components.","-","-","-","-","-","Yes","Susceptibility to acute infection-induced Encephalopathy","#614850","-","-","-","little information","x","Homozygous null mice are viable but exhibit abnormalities of the innate immune system.","-","TICAM1","-","TICAM1:tumorigenesis;nervous system phenotype;liver/biliary system phenotype;limbs/digits/tail phenotype;homeostasis/metabolism phenotype;growth/size phenotype;digestive/alimentary phenotype;immune system phenotype;vision/eye phenotype;hematopoietic system phenotype","-","-","-","-","MED","Postnatal-biased","-","DEL","-","TICAM1|0.066","Not_SegDup","x","x",0,0,1,0,1,1]
[93,"6053_3|12:54218922-58779615","CDK2","Ser/Thr protein kinase involved in the cell cycle","-","-","-","-","-","Yes","x","x","-","-","-","little information","x","Reproductive system abnormalities are observed in mice homozygous for disruptions in this gene. Gametogenesis fails in both males and females, leading to atrophy of the testes and ovaries. Both sexes are sterile.","-","-","-","CDK2:tumorigenesis;muscle phenotype;liver/biliary system phenotype;homeostasis/metabolism phenotype;growth/size phenotype;endocrine/exocrine gland phenotype;embryogenesis phenotype;cellular phenotype;cardiovascular system phenotype;immune system phenotype;reproductive system phenotype;vision/eye phenotype;hematopoietic system phenotype;mortality/aging;integument phenotype","-","-","-","-","MED","Prenatal-biased","-","DUP","-","CDK2|1","Not_SegDup","x","x",0,0,1,0,1,1]
[94,"3439_3|17:17156307-18262979; 2211_1|17:17169258-20101517","SREBF1","Transcription factor that binds to the sterol regulatory element-1 (SRE1); it is involved in sterol biosynthesis.","-","-","-","-","-","Yes","x","x","-","-","-","little information","x","Mice homozygous for a knock-out allele of transcript A die between E11.5 and E14.5. Mice homozygous for a knock-out allele of transcript C exhibit decreased circulating triglyceride levels. Mice homozygous for a gene trap allele exhibit decreased hepatic triglyceride storage.","-","-","-","SREBF1:liver/biliary system phenotype;homeostasis/metabolism phenotype;mortality/aging","-","-","-","-","MED","Unbiased","-","NAHR, DEL-17q-RAI1","-","SREBF1|0.168","SegDup","x","x",0,1,0,0,0,0]
[95,"5089_5|2:102292943-102345460","IL1RL1","Member of the interleukin 1 receptor family","-","-","-","-","-","Yes","x","x","-","-","-","little information","x","Mice homozygous for disruptions in this gene display an abnormal Th2 type inflammatory response.","-","-","-","IL1RL1:normal phenotype;immune system phenotype;hematopoietic system phenotype","-","-","-","-","veryLOW_UNEXP","NA","-","DEL","-","IL1RL1|0.116","Not_SegDup","x","x",0,0,0,0,0,0]
[96,"14237_2650|9:103456776-107140273","ABCA1","cholesterol efflux transporter (participates in cellular lipid removal pathway)","-","-","-","-","-","Yes","-","#604091; #205400; #143890","-","ABCA1","-"," ABCA1 and ABCG1 mediate the activation of intracellular signaling pathways primarily through the efflux of cholesterol and oxysterols to apoA-I/HDL; mutation od ABCA1 leads to dyslipidemia","22488423;22528521 ","Homozygous null mutants die perinatally with placental defects. Survivors show altered steroidogenesis, defective lipid export in Golgi, low serum cholesterol, lipid accumulation in macrophages and lung, reduced fertility and kidney and heart defects.","-","-","-","ABCA1: nervous system phenotype;renal/urinary system phenotype;muscle phenotype;liver/biliary system phenotype;homeostasis/metabolism phenotype;growth/size phenotype;endocrine/exocrine gland phenotype;embryogenesis phenotype;digestive/alimentary phenotype;cellular phenotype;cardiovascular system phenotype;immune system phenotype;respiratory system phenotype;reproductive system phenotype;other phenotype;hematopoietic system phenotype;mortality/aging","-","-","-","-","MED","Prenatal-biased","-","DEL","yes","ABCA1|0.628","Not_SegDup","x","Association with CREBBP (Rubinstein-Taybi syndrome - \n#180849)\n#180849)",0,0,0,0,0,0]
[97,"9756_201|9:132572435-132597937","ABL1","tyrosine kinase implicated in processes of cell differentiation, cell division, cell adhesion, and stress response ","-","-","-","-","-","Yes","-","#608232","ABL1","-","-","ABL1 is an oncogene required for the development of leukaemias initiated by retroviruses or chromosome translocations.",23842646,"Mice homozygous for targeted mutations that inactivate the gene have increased perinatal and postnatal mortality and may display foreshortened crania, abnormal development of spleen, head, heart and eye, reduced B and T cell populations, and osteoporosis.","-","ABL1","-","ABL1: normal phenotype;nervous system phenotype;muscle phenotype;liver/biliary system phenotype;homeostasis/metabolism phenotype;growth/size phenotype;embryogenesis phenotype;digestive/alimentary phenotype;craniofacial phenotype;cellular phenotype;cardiovascular system phenotype;behavior/neurological phenotype;immune system phenotype;respiratory system phenotype;skeleton phenotype;vision/eye phenotype;hematopoietic system phenotype;mortality/aging","-","-","-","Yes","HI","Prenatal-biased","yes","DEL","yes","ABL1|0.995","Not_SegDup","Pathway with TWIST1 (Saethre-Chotzen syndrome - #101400)","x",1,1,1,1,1,1]
[98,"5444_3|17:76953064-77782267","ARHGDIA","inhibitor of Aplysia Ras-related homologs (ARHs)","-","-","-","-","-","Yes","-","#615244","-","ARHGDIA","-","Mutations in ARHGDIA causes nephrotic syndrome",23867502,"Mice homozygous for a targeted null mutation develop nephrotic syndrome, including renal tubule dilation and degeneration, leading to premature death from renal failure. Male mice are sterile and female mice exhibit reduced fertility from postimplantation defects.","-","ARHGDIA","-","ARHGDIA: renal/urinary system phenotype;homeostasis/metabolism phenotype;endocrine/exocrine gland phenotype;behavior/neurological phenotype;immune system phenotype;reproductive system phenotype;hematopoietic system phenotype;mortality/aging","Yes","Yes","-","-","HI","Unbiased","-","DUP","-","ARHGDIA|0.091","Not_SegDup","x","x",1,1,1,0,1,1]
[99,"8588_201|3:195971510-197675831","PCYT1A","choline transferase","-","-","-","-","-","Yes","-","-","-","-","-","Mutations in PCYT1A lead to the autosomal recessive Spondylometaphyseal Dysplasia with Cone-Rod Dystrophy","24387991; 24387990 ","Embryos homozygous for a targeted null mutation fail to form blastocysts, do not develop past E3.5, and fail to implant.","-","-","-","PCYT1A: homeostasis/metabolism phenotype;growth/size phenotype;embryogenesis phenotype;cardiovascular system phenotype;immune system phenotype;respiratory system phenotype;reproductive system phenotype;mortality/aging","-","-","-","-","MED","Unbiased","-","DEL","yes","PCYT1A|0.706","Not_SegDup","Physical interaction with ACTB (Juvenile onset dystonia - #607371; Baraitser-Winter syndrome - #243310)","Association with TBX1 (Velocardiofacial syndrome - #192430; DiGeorge syndrome - #188400)",0,0,0,0,0,0]
[100,"4260_1|2:119603876-119882278","STEAP3","STEAP family member 3, metalloreductase; acts downstream of p53 to interface apoptosis and cell cycle progression","-","-","-","-","-","Yes","x","x","-","-","-","little information","x","Mice homozygous for a targeted mutation of this gene are anemic, have a deficiency in transferrin-mediated iron uptake by reticulocytes, and reduced exosomal protein secretion in mouse embryo fibroblasts (MEFs) and bone marrow-derived dendritic cells (BMDCs).","-","-","-","STEAP3:liver/biliary system phenotype;homeostasis/metabolism phenotype;cellular phenotype;cardiovascular system phenotype;immune system phenotype;reproductive system phenotype;hematopoietic system phenotype","-","-","-","-","LOW","Unbiased","-","DUP","-","STEAP3|0.183","Not_SegDup","Pathway with TP53","x",0,0,0,0,0,0]
[101,"8638_201|14:35203374-35369853","BRMS1L","Component of the mSin3a family of histone deacetylase complexes","-","-","-","-","-","-","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","MED","Unbiased","Yes","DEL_disr","yes","BRMS1L|0.225","Not_SegDup","x","x",0,0,1,0,0,1]
[102,"8587_210|3:139760896-140127703","CEP70","Centrosomal protein 70kDa","-","-","-","-","-","-","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","MED","Unbiased","Yes","DUP_disr","yes","CEP70|0.286","Not_SegDup","x","x",0,0,1,0,0,1]
[103,"1960_301|7:102699832-102798745","PSMC2","The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator.","-","-","-","-","-","-","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","HI","Unbiased","-","DEL","yes","PSMC2|0.885","Not_SegDup","x","x",0,0,1,0,1,1]
[104,"8404_201|6:169136788-170761395","PSMB1","Member of the proteasome B-type family.","-","-","-","-","-","-","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","HI","Unbiased","-","DEL","yes","PSMB1|0.941","Not_SegDup","x","x",0,0,1,0,1,1]
[105,"17015_1|22:17257787-19795780; 3183_7|22:17241748-19819918; 4271_1|22:17257787-19795780; 8627_201|22:17257787-19793730","TSSK2","Ser/Thr protein kinase highly expressed in testis","-","-","-","-","-","-","x","x","-","-","-","little information","x","Male mice homozygous for a knock-out allele of Tssk1 and 2 are infertile due to arrested spermatogenesis.","-","-","-","-","-","-","-","-","MED","Prenatal-biased","-","NAHR, DEL/DUP-22q","-","TSSK2|0.173","SegDup","x","x",0,0,0,0,0,0]
[106,"18172_302|10:34963905-35536952","CUL2","Cullin 2","-","-","-","-","-","-","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","MED","Unbiased","-","DUP","-","CUL2|0.681","Not_SegDup","Physical interaction and Pathway with VHL","Association with VHL",0,0,1,0,0,1]
[107,"14181_2940|15:82906265-82985247","ZSCAN2","Transcription factor","-","-","-","-","-","-","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","MED","Prenatal-biased","-","DUP","-","ZSCAN2|0.616","Not_SegDup","x","x",0,0,0,0,0,0]
[108,"14331_4450|18:72085223-73670156","ZNF516","Zinc-finger protein","-","-","-","-","-","-","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","MED","Prenatal-biased","-","DEL","-","ZNF516|0.161","Not_SegDup","x","x",0,0,0,0,0,0]
[109,"8658_201|1:98175622-100923952","RTCD1","Member of the RNA 3'-phosphate cyclase family","-","-","-","-","-","-","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","HI","Unbiased","-","DEL","-","RTCD1|0.122","Not_SegDup","x","x",0,0,0,0,0,0]
[110,"5220_3|3:19127998-19640299","KCNH8","Alpha subunit of K+ channel, voltage-gated, subfamily H","-","-","-","-","-","-","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","MED","Prenatal-biased","-","DUP","-","KCNH8|0.112","Not_SegDup","x","x",1,1,0,0,0,0]
[111,"14181_2940|15:82906265-82985247","SCAND2","Pseudogene","-","-","-","-","-","-","x","x","-","-","-","little information","x","x","-","-","-","-","-","-","-","-","MED","Unbiased","yes","DUP_disr","yes","-","SegDup","x","x",0,0,0,0,0,0]
[112,"14237_2650|9:103456776-107140273","SMC2","member of the structural maintenance of chromosomes","-","-","-","-","-","-","-","-","-","-","-","SMC2 is part of the complex that is responsible for tightly packaging replicated genomic DNA prior to mitosis",23095742,"x","-","-","-","-","-","-","-","Yes","MED","Prenatal-biased","-","DEL","yes","SMC2|0.878","Not_SegDup","x","x",0,0,0,0,1,1]
[113,"5386_3|6:156785155-158489874","SNX9","involved in intracellular trafficking (e.g. endocytosis, macropinocytosis, F-actin nucleation)","-","-","-","-","-","-","-","-","-","-","-","SNX9 is involved in the spatiotemporal control of endocytosis",23823722,"x","-","-","-","-","Yes","-","-","Yes","MED","Postnatal-biased","-","DEL","-","SNX9|0.143","Not_SegDup","x","Association with SYNJ1 (Early-onset Parkinson disease - #615530)",0,0,0,1,1,1]

{"sheet":"Table S14C. Gene candidacy tier","index":3,"n_rows":114,"n_cols":17,"rows_kept":114,"cut":false,"hidden":false,"merged":[]}
["NetBag2g_113g_w10kbfk","Dominant known disease_genes","FMRP_Darnell","FMRP_Ascano","Synapse_Grant-full","ExprBspan_BrainAny_log2rpkm3.0","ExprBspan_BrainAny_log2rpkm4.5","ExprBspan_NotBrainExprF","hi015","hi035","hi055","NeuroF","NeuroF_EM","Development_EM","Candidate_stringent","Candidate_broad","Candidate_broad_dev"]
["EHMT1","known ASD or ID genes",1,1,0,1,0,0,1,0,0,0,0,1,1,1,1]
["SMARCA2","known ASD or ID genes",1,0,0,1,1,0,1,1,1,1,0,1,1,1,1]
["NRXN1","known ASD or ID genes",1,0,1,1,1,0,0,0,0,1,1,1,1,1,1]
["SHANK2","known ASD or ID genes",1,0,1,1,0,0,1,0,0,1,1,0,1,1,1]
["SYNGAP1","known ASD or ID genes",1,0,1,1,1,0,1,1,0,1,1,1,1,1,1]
["UBE3A","known ASD or ID genes",0,0,0,1,1,0,1,1,0,1,0,1,0,1,1]
["ZEB2","known ID genes",1,0,0,1,1,0,1,1,1,1,0,1,1,1,1]
["FLNA","known ID genes",0,1,1,1,1,0,1,1,1,0,0,0,1,1,1]
["IKBKG","known ID genes",0,0,0,0,0,0,1,1,0,0,0,0,0,0,0]
["SKI","known ID genes",1,0,0,1,1,0,1,0,0,1,1,1,1,1,1]
["LARGE","-",1,1,0,1,1,0,0,0,0,0,0,0,1,1,1]
["PLCB1","-",1,1,1,1,1,0,1,1,0,1,1,1,1,1,1]
["SETD5","-",1,0,0,1,0,0,1,1,0,0,0,0,1,1,1]
["ABL1","-",0,1,0,1,1,0,1,1,1,1,1,1,1,1,1]
["SNX9","-",0,1,1,0,0,0,0,0,0,0,0,0,1,1,1]
["SYNCRIP","-",0,0,1,1,1,0,1,1,1,0,0,0,1,1,1]
["TRIP12","-",1,0,0,1,0,0,1,1,1,0,0,0,1,1,1]
["NRXN3","-",1,0,1,1,1,0,1,1,0,1,1,1,1,1,1]
["LSAMP","-",0,0,1,1,1,0,1,1,1,1,0,0,1,1,1]
["MAPK3","-",0,0,1,1,1,0,1,1,1,1,1,0,1,1,1]
["CRKL","-",0,0,1,1,1,0,1,1,1,1,0,1,1,1,1]
["MAPK7","-",0,1,0,1,1,0,1,1,1,1,0,1,1,1,1]
["CSNK1D","-",0,0,1,1,1,0,1,1,1,0,0,1,1,1,1]
["CACNA1B","-",1,0,0,1,0,0,1,1,0,1,1,0,1,1,1]
["PTPRD","-",1,0,1,1,1,0,1,1,1,0,0,0,1,1,1]
["RAB5A","-",0,0,1,1,1,0,1,1,1,1,1,0,1,1,1]
["TAOK2","-",1,1,1,1,1,0,1,1,1,1,1,1,1,1,1]
["PPP3CB","-",0,0,1,1,1,0,1,1,1,1,1,1,1,1,1]
["ARHGAP32","-",1,0,0,1,1,0,0,0,0,1,0,0,1,1,1]
["DLGAP2","-",1,0,1,0,0,0,1,0,0,1,0,0,1,1,1]
["DTNA","-",1,0,1,1,1,0,1,1,1,1,0,0,1,1,1]
["TNK2","-",1,0,0,1,1,0,1,1,0,0,0,0,1,1,1]
["ERCC6","-",0,0,0,0,0,0,0,0,0,1,0,0,0,1,1]
["RAC3","-",0,0,0,1,1,0,1,1,1,1,1,0,0,1,1]
["CBS","-",0,0,0,1,1,0,1,1,0,1,0,0,0,1,1]
["DBT","-",0,0,1,0,0,0,1,0,0,0,0,0,0,1,1]
["RER1","-",0,0,0,1,1,0,1,1,0,0,0,0,0,1,1]
["ARHGDIA","-",0,0,1,1,1,0,0,0,0,1,1,1,0,1,1]
["SMC2","-",0,1,0,1,0,0,1,1,1,0,0,0,0,1,1]
["SNRPN","-",0,0,0,1,1,0,1,1,1,0,0,0,0,1,1]
["PIK3CB","-",0,0,0,1,0,0,1,1,1,1,1,1,0,1,1]
["PARD3","-",0,1,0,1,0,0,1,1,0,1,1,0,0,1,1]
["ANKS1B","-",0,0,1,1,0,0,1,0,0,1,0,0,0,1,1]
["RAP1GDS1","-",0,0,1,1,1,0,1,0,0,0,0,0,0,1,1]
["DPP6","-",0,0,1,1,1,0,0,0,0,0,0,0,0,1,1]
["SH3GL3","-",0,0,1,1,1,0,0,0,0,1,0,0,0,1,1]
["CAMK2G","-",0,0,1,1,1,0,1,1,0,1,1,0,0,1,1]
["RIMS1","-",0,0,1,1,1,0,1,1,0,1,1,0,0,1,1]
["CYFIP1","-",0,0,1,1,0,0,1,0,0,1,1,1,0,1,1]
["CHRNA7","-",0,0,0,0,0,1,1,1,0,1,1,1,0,1,1]
["GRID2","-",0,0,0,1,1,0,1,0,0,1,0,0,0,1,1]
["CHD2","-",0,0,0,1,0,0,1,1,0,0,0,0,0,1,1]
["UHRF1","-",0,0,0,1,0,0,1,0,0,0,0,0,0,1,1]
["BHLHE22","-",0,0,0,1,1,0,0,0,0,0,0,0,0,1,1]
["SOD2","-",0,0,0,1,1,0,1,1,1,1,1,1,0,1,1]
["DBI","-",0,0,0,1,1,0,0,0,0,0,0,0,0,1,1]
["BAZ1B","-",0,0,0,1,1,0,1,1,0,0,0,1,0,1,1]
["CDK4","-",0,0,0,1,1,0,1,1,1,0,1,1,0,1,1]
["KLF13","-",0,0,0,1,1,0,1,1,1,0,0,1,0,1,1]
["STAU2","-",0,0,0,1,1,0,1,1,0,0,0,0,0,1,1]
["LIMK1","-",0,0,0,1,1,0,1,0,0,1,1,1,0,1,1]
["WDR4","-",0,0,0,0,0,0,1,1,1,0,0,0,0,1,1]
["TBP","-",0,0,0,1,0,0,1,1,1,0,0,0,0,1,1]
["NTSR2","-",0,0,0,1,1,0,0,0,0,1,0,0,0,1,1]
["ATOH1","-",0,0,0,0,0,0,1,1,1,1,1,1,0,1,1]
["MAPK11","-",0,0,0,1,1,0,1,1,1,1,1,0,0,1,1]
["ETS1","-",0,0,0,0,0,0,1,1,1,1,0,1,0,1,1]
["TICAM1","-",0,0,0,1,0,0,0,0,0,0,0,1,0,1,1]
["CDK2","-",0,0,0,1,1,0,1,1,1,0,0,1,0,1,1]
["MAPK8","-",0,0,0,1,1,0,1,1,1,1,1,1,0,1,1]
["MAPK12","-",0,0,0,1,0,0,1,1,0,1,1,1,0,1,1]
["SYNJ2","-",0,0,0,1,0,0,1,0,0,1,1,0,0,1,1]
["PSMC2","-",0,0,0,1,1,0,1,1,1,0,0,1,0,1,1]
["PSMB1","-",0,0,0,1,1,0,1,1,1,0,0,1,0,1,1]
["SMAP1","-",0,0,0,1,1,0,1,0,0,0,0,1,0,0,1]
["TUBGCP5","-",0,0,0,0,0,0,0,0,0,0,0,1,0,0,1]
["PARK2","-",0,0,0,0,0,0,1,0,0,1,1,0,0,0,1]
["RFX3","-",0,0,0,1,0,0,1,1,1,0,1,1,0,0,1]
["MAX","-",0,0,0,1,1,0,1,0,0,1,0,1,0,0,1]
["KAT2B","-",0,0,0,1,0,0,0,0,0,0,0,1,0,0,1]
["CYP7B1","-",0,0,0,0,0,0,1,0,0,1,1,1,0,0,1]
["PRKAB2","-",0,0,0,1,0,0,1,1,1,0,0,1,0,0,1]
["ESR2","-",0,0,0,0,0,1,1,0,0,1,1,1,0,0,1]
["BRMS1L","-",0,0,0,1,0,0,1,0,0,0,0,1,0,0,1]
["BNC1","-",0,0,0,0,0,1,1,0,0,0,0,1,0,0,1]
["CUL2","-",0,0,0,1,0,0,1,1,1,0,0,1,0,0,1]
["CEP70","-",0,0,0,1,0,0,1,0,0,0,0,1,0,0,1]
["ABCA1","-",0,0,0,0,0,0,1,1,1,0,0,0,0,0,0]
["PCYT1A","-",0,0,0,0,0,0,1,1,1,0,0,0,0,0,0]
["SCAPER","-",0,0,0,1,0,0,0,0,0,0,0,0,0,0,0]
["DDX53","-",0,0,0,0,0,1,0,0,0,0,0,0,0,0,0]
["MSI2","-",0,0,0,1,0,0,1,0,0,0,0,0,0,0,0]
["RNASE6","-",0,0,0,0,0,0,1,1,0,0,0,0,0,0,0]
["UBE2W","-",0,0,0,1,0,0,1,1,0,0,0,0,0,0,0]
["GALR1","-",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["RALGAPA1 (=GARNL1)","-",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["SNX14","-",0,0,0,1,0,0,0,0,0,0,0,0,0,0,0]
["CHD1L","-",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["PMPCB","-",0,0,0,1,1,0,1,0,0,0,0,0,0,0,0]
["CUTA","-",0,0,0,1,1,0,1,0,0,0,0,0,0,0,0]
["STAC2","-",0,0,0,1,1,0,1,0,0,0,0,0,0,0,0]
["SREBF1","-",0,0,0,1,1,0,1,0,0,0,1,0,0,0,0]
["IL1RL1","-",0,0,0,0,0,1,0,0,0,0,0,0,0,0,0]
["WTAP","-",0,0,0,1,1,0,1,0,0,0,0,0,0,0,0]
["STEAP3","-",0,0,0,0,0,0,1,0,0,0,0,0,0,0,0]
["RPL19","-",0,0,0,1,1,0,1,0,0,0,0,0,0,0,0]
["TSSK2","-",0,0,0,1,0,0,1,0,0,0,0,0,0,0,0]
["ZSCAN2","-",0,0,0,1,0,0,1,1,1,0,0,0,0,0,0]
["ZNF516","-",0,0,0,0,0,0,1,0,0,0,0,0,0,0,0]
["RTCD1","-",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["RNASE1","-",0,0,0,1,1,0,0,0,0,0,0,0,0,0,0]
["KCNH8","-",0,0,0,0,0,0,0,0,0,1,1,0,0,0,0]
["SCAND2","-",0,0,0,0,0,1,0,0,0,0,0,0,0,0,0]

{"sheet":"Table S14D. Functional Enrichm.","index":4,"n_rows":5533,"n_cols":5,"rows_kept":5533,"cut":false,"hidden":false,"merged":[]}
["GsID","GsName","P_Value","FDR_BH 10%","Symbols"]
["KEGG:04722","Neurotrophin signaling pathway",7.7528698587375807E-9,4.2888876058536302E-5,"PIK3CB;MAPK3;CRKL;CAMK2G;MAPK8;MAPK11;MAPK12;MAPK7;ARHGDIA;ABL1"]
["KEGG:04010","MAPK signaling pathway",2.91375498433889E-8,4.9323942728117699E-5,"IKBKG;MAPK3;CACNA1B;MAPK7;MAX;MAPK11;MAPK12;TAOK2;RAC3;MAPK8;CRKL;PPP3CB;FLNA"]
["GO:0033554","cellular response to stress",3.2994512389541501E-8,4.9323942728117699E-5,"ABL1;CBS;CDK2;CRKL;CSNK1D;ERCC6;ETS1;MAX;MAPK3;MAPK7;MAPK8;MAPK11;PSMB1;PSMC2;MAPK12;SOD2;SREBF1;IKBKG;BAZ1B;TAOK2;CHD1L;ZEB2;SMC2;PLCB1;UHRF1"]
["GO:0004707","MAP kinase activity",3.5664456057930397E-8,4.9323942728117699E-5,"MAPK3;MAPK7;MAPK8;MAPK11;MAPK12"]
["GO:0006468","protein phosphorylation",5.7505775175639002E-8,6.3624389654327006E-5,"ABL1;CAMK2G;CBS;CDK2;CDK4;CHRNA7;CSNK1D;ERCC6;LIMK1;PARK2;PIK3CB;PPP3CB;MAPK3;MAPK7;MAPK8;MAPK11;MAPK12;IKBKG;KAT2B;BAZ1B;TAOK2;ZEB2;TNK2;TSSK2;PARD3"]
["GO:0051403","stress-activated MAPK cascade",7.8747216076271598E-8,7.2604933222322402E-5,"CBS;CRKL;ERCC6;MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TAOK2;ZEB2;PLCB1"]
["GO:0031098","stress-activated protein kinase signaling cascade",9.2011688623913494E-8,7.2715523066784206E-5,"CBS;CRKL;ERCC6;MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TAOK2;ZEB2;PLCB1"]
["KEGG:05131","Shigellosis",1.6534848603865101E-7,1.14338478095727E-4,"CRKL;ABL1;IKBKG;MAPK8;MAPK3;MAPK11;MAPK12"]
["GO:0031399","regulation of protein modification process",2.0103958068614901E-7,1.2357232892842E-4,"ABL1;CBS;CDK2;CHRNA7;CSNK1D;ERCC6;LIMK1;PARK2;PIK3CB;MAPK3;MAPK8;MAPK11;PSMB1;PSMC2;SKI;IKBKG;KAT2B;TAOK2;ZEB2;TNK2;PARD3;TICAM1"]
["GO:0044093","positive regulation of molecular function",2.2392354653200499E-7,1.23874505941505E-4,"ABL1;CHRNA7;ERCC6;ESR2;GALR1;PIK3CB;MAPK3;MAPK8;MAPK11;PSMB1;PSMC2;RAP1GDS1;SKI;IKBKG;SYNGAP1;TAOK2;ZEB2;PLCB1;NTSR2;UHRF1;SNX9;PARD3;TICAM1;RALGAPA1"]
["KEGG:05142","Chagas disease (American trypanosomiasis)",4.8550699931599298E-7,2.44165883656007E-4,"MAPK8;MAPK11;MAPK12;MAPK3;TICAM1;IKBKG;PLCB1;PIK3CB"]
["GO:0043085","positive regulation of catalytic activity",8.1117758705724203E-7,3.73952867633389E-4,"ABL1;CHRNA7;ERCC6;GALR1;PIK3CB;MAPK3;MAPK8;MAPK11;PSMB1;PSMC2;RAP1GDS1;IKBKG;SYNGAP1;TAOK2;ZEB2;PLCB1;NTSR2;UHRF1;SNX9;PARD3;RALGAPA1"]
["GO:0004672","protein kinase activity",9.3601062444336798E-7,3.9830852110928598E-4,"ABL1;CAMK2G;CDK2;CDK4;CSNK1D;LIMK1;PRKAB2;MAPK3;MAPK7;MAPK8;MAPK11;MAPK12;BAZ1B;TAOK2;TNK2;TSSK2;KCNH8"]
["GO:0019899","enzyme binding",1.35393780717327E-6,5.3499885352018104E-4,"ABCA1;ABL1;CBS;ESR2;FLNA;PARK2;PPP3CB;PRKAB2;MAPK3;MAPK8;SKI;CUL2;KAT2B;TAOK2;RIMS1;CYFIP1;PLCB1;SNX9;CUTA;PARD3;TICAM1"]
["GO:0004674","protein serine/threonine kinase activity",1.4929999488261599E-6,5.5061838112708704E-4,"CAMK2G;CDK2;CDK4;CSNK1D;LIMK1;PRKAB2;MAPK3;MAPK7;MAPK8;MAPK11;MAPK12;TAOK2;TNK2;TSSK2"]
["GO:0032268","regulation of cellular protein metabolic process",1.8476255787114301E-6,6.0187449364768595E-4,"ABL1;CBS;CDK2;CHRNA7;CSNK1D;ERCC6;LIMK1;PARK2;PIK3CB;MAPK3;MAPK8;MAPK11;PSMB1;PSMC2;SKI;IKBKG;KAT2B;TAOK2;ZEB2;TNK2;UHRF1;PARD3;TICAM1"]
["KEGG:05200","Pathways in cancer",1.8853763538785901E-6,6.0187449364768595E-4,"ABL1;CRKL;PIK3CB;IKBKG;RAC3;MAPK8;CUL2;MAX;CDK4;CDK2;ETS1;MAPK3"]
["GO:0000165","MAPK cascade",1.9583768773785899E-6,6.0187449364768595E-4,"CBS;CRKL;ERCC6;MAPK3;MAPK7;MAPK8;MAPK11;MAPK12;IKBKG;SYNGAP1;TAOK2;ZEB2;PLCB1"]
["GO:0016773","phosphotransferase activity, alcohol group as acceptor",2.2420252120616198E-6,6.5278334069078395E-4,"ABL1;CAMK2G;CDK2;CDK4;CSNK1D;LIMK1;PIK3CB;PRKAB2;MAPK3;MAPK7;MAPK8;MAPK11;MAPK12;BAZ1B;TAOK2;TNK2;TSSK2;KCNH8"]
["GO:0035666","TRIF-dependent toll-like receptor signaling pathway",3.64101750442974E-6,9.8868708397601801E-4,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["GO:0051173","positive regulation of nitrogen compound metabolic process",3.75315053570072E-6,9.8868708397601801E-4,"ABCA1;ATOH1;CDK2;ERCC6;ETS1;GALR1;PPP3CB;MAPK3;MAPK7;RFX3;SKI;SMARCA2;SOD2;SREBF1;TBP;UBE3A;KAT2B;BAZ1B;PLCB1;UHRF1;KLF13;TICAM1"]
["KEGG:04912","GnRH signaling pathway",5.2306942003361601E-6,1.1785486640928601E-3,"PLCB1;CAMK2G;MAPK11;MAPK12;MAPK7;MAPK3;MAPK8"]
["GO:0002756","MyD88-independent toll-like receptor signaling pathway",5.2655760369919297E-6,1.1785486640928601E-3,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["NCI:29","NCI:BCR_5PATHWAY",5.2655760369919297E-6,1.1785486640928601E-3,"CAMK2G;ETS1;PPP3CB;MAPK3;MAPK8;IKBKG"]
["KEGG:04620","Toll-like receptor signaling pathway",5.5853168591451797E-6,1.1785486640928601E-3,"MAPK3;MAPK11;MAPK12;MAPK8;TICAM1;IKBKG;PIK3CB"]
["KEGG:04723","Retrograde endocannabinoid signaling",5.5853168591451797E-6,1.1785486640928601E-3,"PLCB1;CACNA1B;MAPK3;MAPK8;MAPK11;MAPK12;RIMS1"]
["GO:0034138","toll-like receptor 3 signaling pathway",5.7521355622753496E-6,1.1785486640928601E-3,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["REACT:1108","REACT: TRAF6 Mediated Induction of proinflammatory cytokines",6.2745813432045998E-6,1.2396779996645701E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8;TICAM1"]
["GO:0034130","toll-like receptor 1 signaling pathway",6.8348954384537998E-6,1.2853484447469499E-3,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["GO:0007243","intracellular protein kinase cascade",7.2413053008922897E-6,1.2853484447469499E-3,"CBS;CRKL;ERCC6;FLNA;PARK2;MAPK3;MAPK7;MAPK8;MAPK11;MAPK12;IKBKG;SYNGAP1;IL1RL1;TAOK2;ZEB2;PLCB1;TICAM1"]
["GO:0016301","kinase activity",7.4245059067160298E-6,1.2853484447469499E-3,"ABL1;CAMK2G;CDK2;CDK4;CSNK1D;LIMK1;PIK3CB;PRKAB2;MAPK3;MAPK7;MAPK8;MAPK11;MAPK12;BAZ1B;TAOK2;TNK2;TSSK2;KCNH8"]
["KEGG:05212","Pancreatic cancer",7.4351320014285001E-6,1.2853484447469499E-3,"PIK3CB;RAC3;IKBKG;MAPK3;MAPK8;CDK4"]
["GO:0031328","positive regulation of cellular biosynthetic process",8.0452243446598792E-6,1.32761569467769E-3,"ABCA1;ATOH1;CDK2;ERCC6;ETS1;GALR1;PPP3CB;MAPK3;MAPK7;RFX3;SKI;SMARCA2;SOD2;SREBF1;TBP;UBE3A;KAT2B;BAZ1B;PLCB1;UHRF1;KLF13;TICAM1"]
["KEGG:04660","T cell receptor signaling pathway",8.1596047756763302E-6,1.32761569467769E-3,"CDK4;IKBKG;PIK3CB;PPP3CB;MAPK3;MAPK11;MAPK12"]
["GO:0007264","small GTPase mediated signal transduction",8.7570516182456201E-6,1.3467279690556699E-3,"ABCA1;ARHGDIA;CDK2;CRKL;LIMK1;MAPK3;MAPK11;RAB5A;RAC3;MAPK12;SYNGAP1;ARHGAP32;TNK2;RALGAPA1"]
["GO:0034134","toll-like receptor 2 signaling pathway",8.7639564146789595E-6,1.3467279690556699E-3,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["REACT:681","REACT: NFkB and MAP kinases activation mediated by TLR4 signaling repertoire",9.49702317475811E-6,1.38256663691479E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8;TICAM1"]
["KEGG:05220","Chronic myeloid leukemia",9.49702317475811E-6,1.38256663691479E-3,"ABL1;IKBKG;CRKL;CDK4;PIK3CB;MAPK3"]
["GO:0007254","JNK cascade",1.0244115176818501E-5,1.4027898607609599E-3,"CBS;CRKL;ERCC6;MAPK8;IKBKG;TAOK2;ZEB2;PLCB1"]
["GO:0002755","MyD88-dependent toll-like receptor signaling pathway",1.02789723987641E-5,1.4027898607609599E-3,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["GO:0009891","positive regulation of biosynthetic process",1.03966710577005E-5,1.4027898607609599E-3,"ABCA1;ATOH1;CDK2;ERCC6;ETS1;GALR1;PPP3CB;MAPK3;MAPK7;RFX3;SKI;SMARCA2;SOD2;SREBF1;TBP;UBE3A;KAT2B;BAZ1B;PLCB1;UHRF1;KLF13;TICAM1"]
["REACT:1115","REACT: TRIF mediated TLR3 signaling",1.1112235372089901E-5,1.4636401447238399E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8;TICAM1"]
["KEGG:04370","VEGF signaling pathway",1.1999322001487101E-5,1.54372672819131E-3,"PPP3CB;PIK3CB;MAPK11;MAPK12;MAPK3;RAC3"]
["GO:0008063","Toll signaling pathway",1.3945405047256299E-5,1.6770865374222199E-3,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["REACT:666","REACT: MyD88-independent cascade",1.3945405047256299E-5,1.6770865374222199E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8;TICAM1"]
["REACT:1150","REACT: Toll Like Receptor 3 (TLR3) Cascade",1.3945405047256299E-5,1.6770865374222199E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8;TICAM1"]
["GO:0016772","transferase activity, transferring phosphorus-containing groups",1.5076033681224501E-5,1.77448124094754E-3,"ABL1;CAMK2G;CDK2;CDK4;CSNK1D;LIMK1;PCYT1A;PIK3CB;PRKAB2;MAPK3;MAPK7;MAPK8;MAPK11;MAPK12;BAZ1B;TAOK2;TNK2;TSSK2;KCNH8"]
["KEGG:04664","Fc epsilon RI signaling pathway",1.7335586672688399E-5,1.9979263640273401E-3,"MAPK11;MAPK12;PIK3CB;MAPK3;MAPK8;RAC3"]
["REACT:608","REACT: MAP kinase activation in TLR cascade",1.8883646126804701E-5,2.0892866074696801E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8"]
["NCI:78","NCI:FOXOPATHWAY",1.8883646126804701E-5,2.0892866074696801E-3,"CDK2;CSNK1D;MAPK8;SOD2;KAT2B"]
["GO:0004702","receptor signaling protein serine/threonine kinase activity",2.0870196918880601E-5,2.26380253637741E-3,"MAPK3;MAPK7;MAPK8;MAPK11;MAPK12"]
["GO:0034142","toll-like receptor 4 signaling pathway",2.13615868781042E-5,2.2725442040321601E-3,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["KEGG:04914","Progesterone-mediated oocyte maturation",2.4440856476094798E-5,2.55107203822182E-3,"MAPK3;CDK2;MAPK8;MAPK11;MAPK12;PIK3CB"]
["KEGG:04728","Dopaminergic synapse",2.7393471284592999E-5,2.8029944695307E-3,"PLCB1;CACNA1B;MAPK8;MAPK11;MAPK12;PPP3CB;CAMK2G"]
["KEGG:04012","ErbB signaling pathway",2.7867804740453501E-5,2.8029944695307E-3,"MAPK8;CRKL;CAMK2G;ABL1;PIK3CB;MAPK3"]
["KEGG:05160","Hepatitis C",2.87813832465406E-5,2.8431895021404099E-3,"TICAM1;IKBKG;MAPK11;MAPK12;MAPK3;PIK3CB;MAPK8"]
["GO:0006974","response to DNA damage stimulus",2.9986033965268698E-5,2.8830013865375499E-3,"ABL1;CDK2;CSNK1D;ERCC6;MAPK3;PSMB1;PSMC2;MAPK12;IKBKG;BAZ1B;TAOK2;CHD1L;SMC2;UHRF1"]
["KEGG:04380","Osteoclast differentiation",3.0226695665071899E-5,2.8830013865375499E-3,"IKBKG;MAPK8;MAPK11;MAPK12;PIK3CB;PPP3CB;MAPK3"]
["GO:0045935","positive regulation of nucleobase-containing compound metabolic process",3.2847928033031403E-5,3.0799108115038901E-3,"ABCA1;ATOH1;CDK2;ERCC6;ETS1;GALR1;PPP3CB;MAPK3;MAPK7;RFX3;SKI;SMARCA2;SREBF1;TBP;UBE3A;KAT2B;BAZ1B;PLCB1;UHRF1;KLF13"]
["NCI:215","NCI:TRAIL_PATHWAY",3.4978294800744799E-5,3.22499878062867E-3,"PIK3CB;MAPK3;MAPK8;IKBKG"]
["GO:0007611","learning or memory",3.6619070787918099E-5,3.3209295016190599E-3,"CHRNA7;PARK2;PPP3CB;SYNGAP1;NRXN1;CYP7B1;PLCB1"]
["KEGG:04621","NOD-like receptor signaling pathway",3.9732719992286797E-5,3.5451839838279101E-3,"IKBKG;MAPK8;MAPK3;MAPK11;MAPK12"]
["NCI:155","NCI:P53REGULATIONPATHWAY",4.3249955928355799E-5,3.7968837108064402E-3,"ABL1;CDK2;CSNK1D;MAPK8;KAT2B"]
["GO:0019226","transmission of nerve impulse",4.3926348064282799E-5,3.7968837108064402E-3,"CACNA1B;CAMK2G;CHRNA7;DTNA;GRID2;PARK2;PPP3CB;SKI;SYNGAP1;DLGAP2;NRXN1;RIMS1;PLCB1;NTSR2;KCNH8"]
["REACT:38","REACT: Activated TLR4 signalling",4.5645806197734501E-5,3.8257677540542798E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8;TICAM1"]
["GO:0035637","multicellular organismal signaling",4.6208296958613999E-5,3.8257677540542798E-3,"CACNA1B;CAMK2G;CHRNA7;DTNA;GRID2;PARK2;PPP3CB;SKI;SYNGAP1;DLGAP2;NRXN1;RIMS1;PLCB1;NTSR2;KCNH8"]
["REACT:609","REACT: MAPK targets/ Nuclear events mediated by MAP kinases",4.6335220448596697E-5,3.8257677540542798E-3,"MAPK11;MAPK3;MAPK7;MAPK8"]
["GO:0009894","regulation of catabolic process",4.9414005985377502E-5,3.99158629116232E-3,"ABL1;CSNK1D;FLNA;PARK2;PIK3CB;RAP1GDS1;SYNGAP1;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0006140","regulation of nucleotide metabolic process",4.9786596907122302E-5,3.99158629116232E-3,"ABCA1;CBS;FLNA;GALR1;RAP1GDS1;SYNGAP1;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0097060","synaptic membrane",5.2944061618696297E-5,4.1840935553518199E-3,"CHRNA7;GRID2;DLGAP2;NRXN1;ARHGAP32;SHANK2;RIMS1;ANKS1B"]
["GO:0007268","synaptic transmission",5.5058540762357101E-5,4.2899133450332297E-3,"CACNA1B;CAMK2G;CHRNA7;DTNA;GRID2;PARK2;PPP3CB;SYNGAP1;DLGAP2;NRXN1;RIMS1;PLCB1;NTSR2;KCNH8"]
["GO:0051254","positive regulation of RNA metabolic process",5.9178870616261702E-5,4.5400448095503998E-3,"ATOH1;CDK2;ERCC6;ETS1;PPP3CB;MAPK3;MAPK7;RFX3;SKI;SMARCA2;SREBF1;TBP;UBE3A;KAT2B;BAZ1B;PLCB1;UHRF1;KLF13"]
["GO:0007265","Ras protein signal transduction",6.0679050984306999E-5,4.5400448095503998E-3,"ABCA1;ARHGDIA;CDK2;CRKL;LIMK1;MAPK3;MAPK11;MAPK12;SYNGAP1"]
["GO:0002224","toll-like receptor signaling pathway",6.0730895861664701E-5,4.5400448095503998E-3,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["GO:0043005","neuron projection",6.3611631618261394E-5,4.6919939481629598E-3,"GRID2;LIMK1;MAX;PARK2;RAC3;SYNGAP1;SYNJ2;DLGAP2;TAOK2;NRXN1;ARHGAP32;SHANK2;ANKS1B"]
["GO:0050890","cognition",6.55068233052543E-5,4.7682071911140404E-3,"CHRNA7;PARK2;PPP3CB;SYNGAP1;NRXN1;CYP7B1;PLCB1"]
["REACT:1151","REACT: Toll Like Receptor 4 (TLR4) Cascade",6.7778594029843897E-5,4.7744953595107303E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8;TICAM1"]
["KEGG:05169","Epstein-Barr virus infection",6.7783959128959494E-5,4.7744953595107303E-3,"CDK2;IKBKG;MAPK8;MAPK11;MAPK12;PIK3CB;TBP;PSMC2"]
["GO:0050877","neurological system process",6.8182417462282698E-5,4.7744953595107303E-3,"CACNA1B;CAMK2G;CHRNA7;DTNA;ERCC6;GRID2;PARK2;PPP3CB;MAPK3;RAC3;SKI;SOD2;SYNGAP1;DLGAP2;NRXN1;CYP7B1;RIMS1;PLCB1;NTSR2;KCNH8"]
["NCI:179","NCI:RB_1PATHWAY",6.9702534233948899E-5,4.81993024227756E-3,"ABL1;CDK2;CDK4;MAPK11;TBP"]
["GO:0010628","positive regulation of gene expression",7.1444543577666795E-5,4.8262811792849697E-3,"ATOH1;CDK2;ETS1;PPP3CB;MAPK3;MAPK7;MAPK8;RFX3;SKI;SMARCA2;SREBF1;TBP;UBE3A;KAT2B;BAZ1B;PLCB1;UHRF1;KLF13"]
["GO:0005057","receptor signaling protein activity",7.1539236569300005E-5,4.8262811792849697E-3,"MAPK3;MAPK7;MAPK8;MAPK11;MAPK12;IL1RL1"]
["KEGG:05203","Viral carcinogenesis",7.7715367199705494E-5,5.1797760403466397E-3,"UBE3A;TBP;IKBKG;MAPK3;PIK3CB;CDK2;CDK4;KAT2B"]
["GO:0031329","regulation of cellular catabolic process",8.4296844143907804E-5,5.4864296474288502E-3,"ABL1;CSNK1D;PARK2;PIK3CB;RAP1GDS1;SYNGAP1;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0071900","regulation of protein serine/threonine kinase activity",8.4299804777919802E-5,5.4864296474288502E-3,"ABL1;CBS;CHRNA7;ERCC6;PIK3CB;MAPK3;MAPK11;IKBKG;KAT2B;ZEB2"]
["GO:0045893","positive regulation of transcription, DNA-dependent",9.9785363519205603E-5,6.35215124583888E-3,"ATOH1;CDK2;ETS1;PPP3CB;MAPK3;MAPK7;RFX3;SKI;SMARCA2;SREBF1;TBP;UBE3A;KAT2B;BAZ1B;PLCB1;UHRF1;KLF13"]
["GO:0006163","purine nucleotide metabolic process",9.9898257120025803E-5,6.35215124583888E-3,"ABCA1;CBS;FLNA;GALR1;PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["KEGG:05211","Renal cell carcinoma",1.07165840207658E-4,6.5658007104778702E-3,"CUL2;CRKL;ETS1;PIK3CB;MAPK3"]
["NCI:38","NCI:CDC42_PATHWAY",1.07165840207658E-4,6.5658007104778702E-3,"ARHGDIA;LIMK1;MAPK3;MAPK8;TNK2"]
["GO:0002221","pattern recognition receptor signaling pathway",1.08005760060283E-4,6.5658007104778702E-3,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["KEGG:04725","Cholinergic synapse",1.08005760060283E-4,6.5658007104778702E-3,"CHRNA7;PLCB1;CACNA1B;MAPK3;CAMK2G;PIK3CB"]
["GO:0043406","positive regulation of MAP kinase activity",1.1517401662136199E-4,6.9254636951018803E-3,"CHRNA7;ERCC6;PIK3CB;MAPK3;MAPK11;IKBKG;ZEB2"]
["NCI:74","NCI:FASPATHWAY",1.1974806211503099E-4,7.1230782754876402E-3,"PIK3CB;MAPK8;MAPK11;IKBKG"]
["GO:0001964","startle response",1.2692412188412101E-4,7.4696195985420703E-3,"GRID2;PARK2;NRXN1"]
["GO:0002758","innate immune response-activating signal transduction",1.3108249489290799E-4,7.6331406499743704E-3,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["GO:0007612","learning",1.3963079514034001E-4,7.9632738011995996E-3,"PARK2;PPP3CB;SYNGAP1;NRXN1;PLCB1"]
["KEGG:05133","Pertussis",1.3963079514034001E-4,7.9632738011995996E-3,"MAPK11;MAPK12;MAPK3;MAPK8;TICAM1"]
["GO:0043405","regulation of MAP kinase activity",1.42915379990903E-4,8.0465980654748602E-3,"CBS;CHRNA7;ERCC6;PIK3CB;MAPK3;MAPK11;IKBKG;ZEB2"]
["GO:0002218","activation of innate immune response",1.44000941518802E-4,8.0465980654748602E-3,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["NCI:134","NCI:MET_PATHWAY",1.5844529580644399E-4,8.6969345134274897E-3,"CRKL;ETS1;MAPK3;MAPK8;RAB5A"]
["GO:0010557","positive regulation of macromolecule biosynthetic process",1.59146260116222E-4,8.6969345134274897E-3,"ATOH1;CDK2;ETS1;PPP3CB;MAPK3;MAPK7;RFX3;SKI;SMARCA2;SREBF1;TBP;UBE3A;KAT2B;BAZ1B;PLCB1;UHRF1;KLF13;TICAM1"]
["GO:0051094","positive regulation of developmental process",1.6035562551872801E-4,8.6969345134274897E-3,"ABL1;ARHGDIA;ATOH1;CHRNA7;ETS1;LIMK1;MAPK8;MAPK11;RFX3;MAPK12;NRXN1;PLCB1;SMAP1"]
["GO:0001932","regulation of protein phosphorylation",1.63128165471505E-4,8.7614078775569305E-3,"ABL1;CBS;CHRNA7;CSNK1D;ERCC6;PARK2;PIK3CB;MAPK3;MAPK11;IKBKG;KAT2B;TAOK2;ZEB2;TNK2;PARD3"]
["REACT:1157","REACT: Toll Receptor Cascades",1.65249357448071E-4,8.7899946673339491E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8;TICAM1"]
["GO:0000187","activation of MAPK activity",1.72857934585864E-4,8.8481853092358901E-3,"CHRNA7;ERCC6;PIK3CB;MAPK3;MAPK11;IKBKG"]
["GO:0072521","purine-containing compound metabolic process",1.75253474420028E-4,8.8481853092358901E-3,"ABCA1;CBS;FLNA;GALR1;PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["NCI:66","NCI:ERBB2ERBB3PATHWAY",1.7786932128224599E-4,8.8481853092358901E-3,"PIK3CB;PPP3CB;MAPK3;MAPK8"]
["REACT:664","REACT: MyD88 cascade initiated on plasma membrane",1.79138965045991E-4,8.8481853092358901E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8"]
["REACT:1112","REACT: TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation",1.79138965045991E-4,8.8481853092358901E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8"]
["REACT:1148","REACT: Toll Like Receptor 10 (TLR10) Cascade",1.79138965045991E-4,8.8481853092358901E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8"]
["REACT:1152","REACT: Toll Like Receptor 5 (TLR5) Cascade",1.79138965045991E-4,8.8481853092358901E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8"]
["KEGG:04662","B cell receptor signaling pathway",1.79138965045991E-4,8.8481853092358901E-3,"IKBKG;PIK3CB;PPP3CB;RAC3;MAPK3"]
["GO:0010627","regulation of intracellular protein kinase cascade",1.86647607310557E-4,9.1374740145309594E-3,"CBS;ERCC6;FLNA;PARK2;MAPK3;IKBKG;SYNGAP1;IL1RL1;TAOK2;ZEB2;PLCB1;TICAM1"]
["REACT:665","REACT: MyD88 dependent cascade initiated on endosome",1.9022877191142001E-4,9.1508310105563005E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8"]
["REACT:1153","REACT: Toll Like Receptor 7/8 (TLR7/8) Cascade",1.9022877191142001E-4,9.1508310105563005E-3,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8"]
["NCI:161","NCI:PDGFRBPATHWAY",2.0610722680600399E-4,9.8291825749207903E-3,"ABL1;ARHGDIA;PIK3CB;MAPK3;MAPK8;RAB5A"]
["NCI:195","NCI:SMAD2_3NUCLEARPATHWAY",2.1397286629515599E-4,1.01170760371351E-2,"CDK2;CDK4;MAX;SKI;KAT2B"]
["KEGG:05152","Tuberculosis",2.2011855830118799E-4,1.0319456479001499E-2,"RAB5A;CAMK2G;PPP3CB;MAPK3;MAPK8;MAPK11;MAPK12"]
["GO:0051329","interphase of mitotic cell cycle",2.3112367309697799E-4,1.0744337475398999E-2,"ABL1;CDK2;CDK4;CSNK1D;PSMB1;PSMC2;CUL2;PLCB1;CEP70;TUBGCP5"]
["REACT:214","REACT: Cell-Cell communication",2.34203135566041E-4,1.07967645495945E-2,"FLNA;MAPK11;MAPK12;MAPK8;PARD3;PIK3CB"]
["GO:0032879","regulation of localization",2.3716206943580399E-4,1.08428146125526E-2,"ABCA1;ABL1;ARHGDIA;CACNA1B;CAMK2G;ETS1;FLNA;PARK2;PIK3CB;PPP3CB;MAPK3;MAPK7;MAPK8;RAB5A;RFX3;IL1RL1;NRXN1;TNK2;PLCB1"]
["REACT:1154","REACT: Toll Like Receptor 9 (TLR9) Cascade",2.3991022044050301E-4,1.0878551962925099E-2,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8"]
["GO:0016044","cellular membrane organization",2.4458298309425701E-4,1.1000268800629501E-2,"ABCA1;ABL1;FLNA;PIK3CB;MAPK3;RAB5A;SH3GL3;UBE3A;SYNGAP1;NRXN1;TNK2;RIMS1;SNX9"]
["GO:0042981","regulation of apoptotic process",2.4782211044465399E-4,1.10560638304825E-2,"ABL1;ARHGDIA;ERCC6;ESR2;ETS1;GRID2;PARK2;PPP3CB;MAPK7;MAPK8;PSMB1;PSMC2;SKI;SOD2;CUL2;IKBKG;SYNGAP1;KCNH8;TICAM1"]
["GO:0061024","membrane organization",2.5240084644635101E-4,1.1064970624992501E-2,"ABCA1;ABL1;FLNA;PIK3CB;MAPK3;RAB5A;SH3GL3;UBE3A;SYNGAP1;NRXN1;TNK2;RIMS1;SNX9"]
["KEGG:05222","Small cell lung cancer",2.5374241243812299E-4,1.1064970624992501E-2,"CDK2;MAX;PIK3CB;IKBKG;CDK4"]
["GO:0051149","positive regulation of muscle cell differentiation",2.5402228296710902E-4,1.1064970624992501E-2,"ABL1;MAPK11;MAPK12;PLCB1"]
["GO:0019901","protein kinase binding",2.6100647605733899E-4,1.1193338207713101E-2,"ABL1;FLNA;PARK2;PRKAB2;SKI;KAT2B;TAOK2;PARD3;TICAM1"]
["GO:0016572","histone phosphorylation",2.6506278112986499E-4,1.1193338207713101E-2,"CDK2;MAPK3;BAZ1B"]
["GO:0034405","response to fluid shear stress",2.6506278112986499E-4,1.1193338207713101E-2,"ABCA1;ETS1;MAPK7"]
["GO:0043113","receptor clustering",2.6506278112986499E-4,1.1193338207713101E-2,"FLNA;SYNGAP1;NRXN1"]
["GO:0051325","interphase",2.7324574651411802E-4,1.1271659501021899E-2,"ABL1;CDK2;CDK4;CSNK1D;PSMB1;PSMC2;CUL2;PLCB1;CEP70;TUBGCP5"]
["GO:0043067","regulation of programmed cell death",2.7336068476574102E-4,1.1271659501021899E-2,"ABL1;ARHGDIA;ERCC6;ESR2;ETS1;GRID2;PARK2;PPP3CB;MAPK7;MAPK8;PSMB1;PSMC2;SKI;SOD2;CUL2;IKBKG;SYNGAP1;KCNH8;TICAM1"]
["GO:0051128","regulation of cellular component organization",2.7944762202674998E-4,1.1271659501021899E-2,"ABL1;ARHGDIA;ESR2;ETS1;LIMK1;PARK2;PIK3CB;MAPK3;MAPK8;RAB5A;SKI;SMARCA2;SYNGAP1;TAOK2;NRXN1;TNK2;CYFIP1;SNX9"]
["REACT:667","REACT: MyD88:Mal cascade initiated on plasma membrane",2.8321776403507598E-4,1.1271659501021899E-2,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8"]
["REACT:1149","REACT: Toll Like Receptor 2 (TLR2) Cascade",2.8321776403507598E-4,1.1271659501021899E-2,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8"]
["REACT:1155","REACT: Toll Like Receptor TLR1:TLR2 Cascade",2.8321776403507598E-4,1.1271659501021899E-2,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8"]
["REACT:1156","REACT: Toll Like Receptor TLR6:TLR2 Cascade",2.8321776403507598E-4,1.1271659501021899E-2,"IKBKG;MAPK11;MAPK3;MAPK7;MAPK8"]
["KEGG:05132","Salmonella infection",2.8321776403507598E-4,1.1271659501021899E-2,"MAPK8;FLNA;MAPK3;MAPK11;MAPK12"]
["GO:0032872","regulation of stress-activated MAPK cascade",2.8765338754742798E-4,1.12858052476055E-2,"CBS;ERCC6;MAPK3;TAOK2;ZEB2;PLCB1"]
["KEGG:05145","Toxoplasmosis",2.8765338754742798E-4,1.12858052476055E-2,"IKBKG;MAPK3;MAPK8;MAPK11;MAPK12;PIK3CB"]
["GO:0070302","regulation of stress-activated protein kinase signaling cascade",2.9940817318674698E-4,1.15972983143427E-2,"CBS;ERCC6;MAPK3;TAOK2;ZEB2;PLCB1"]
["KEGG:04930","Type II diabetes mellitus",2.9978554934038498E-4,1.15972983143427E-2,"PIK3CB;MAPK3;MAPK8;CACNA1B"]
["GO:0080134","regulation of response to stress",3.08638843078164E-4,1.18568755549195E-2,"ABL1;CBS;ERCC6;MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;IL1RL1;TAOK2;ZEB2;PLCB1;TICAM1"]
["GO:0032147","activation of protein kinase activity",3.16087878738663E-4,1.20592975529813E-2,"CHRNA7;ERCC6;PIK3CB;MAPK3;MAPK11;IKBKG;TAOK2;PARD3"]
["KEGG:04910","Insulin signaling pathway",3.3694969079003597E-4,1.2709068281319499E-2,"MAPK8;MAPK3;PRKAB2;PIK3CB;SREBF1;CRKL"]
["GO:0042325","regulation of phosphorylation",3.3771385346239398E-4,1.2709068281319499E-2,"ABL1;CBS;CHRNA7;CSNK1D;ERCC6;PARK2;PIK3CB;MAPK3;MAPK11;IKBKG;KAT2B;TAOK2;ZEB2;TNK2;PARD3"]
["GO:0016567","protein ubiquitination",3.4838717007084702E-4,1.30221474650806E-2,"CDK2;LIMK1;PARK2;PSMB1;PSMC2;UBE3A;TRIP12;TNK2;UBE2W;TICAM1"]
["REACT:333","REACT: ERK/MAPK targets",3.6026856563900299E-4,1.3375877215536699E-2,"MAPK11;MAPK3;MAPK7"]
["GO:0010941","regulation of cell death",3.7595662347822E-4,1.38652802738768E-2,"ABL1;ARHGDIA;ERCC6;ESR2;ETS1;GRID2;PARK2;PPP3CB;MAPK7;MAPK8;PSMB1;PSMC2;SKI;SOD2;CUL2;IKBKG;SYNGAP1;KCNH8;TICAM1"]
["GO:0031349","positive regulation of defense response",3.7980850056632697E-4,1.3914573676377001E-2,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;IL1RL1;TICAM1"]
["KEGG:05166","HTLV-I infection",3.9892440332141098E-4,1.4518748678776601E-2,"PPP3CB;IKBKG;MAPK8;PIK3CB;CDK4;ETS1;TBP;KAT2B"]
["REACT:523","REACT: Immune System",4.0568391929263301E-4,1.46615846490767E-2,"CAMK2G;CRKL;CUL2;IKBKG;MAPK11;MAPK12;MAPK3;MAPK7;MAPK8;PARK2;PIK3CB;PSMB1;PSMC2;TICAM1;TRIP12;UBE2W;UBE3A"]
["GO:0006897","endocytosis",4.1080000372503499E-4,1.46615846490767E-2,"ABCA1;ABL1;PIK3CB;MAPK3;RAB5A;SH3GL3;UBE3A;TNK2;SNX9"]
["GO:0010324","membrane invagination",4.1080000372503499E-4,1.46615846490767E-2,"ABCA1;ABL1;PIK3CB;MAPK3;RAB5A;SH3GL3;UBE3A;TNK2;SNX9"]
["GO:0071902","positive regulation of protein serine/threonine kinase activity",4.1577020511292999E-4,1.47438511197739E-2,"CHRNA7;ERCC6;PIK3CB;MAPK3;MAPK11;IKBKG;ZEB2"]
["GO:0045089","positive regulation of innate immune response",4.3893303974332199E-4,1.53941269931858E-2,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["KEGG:05014","Amyotrophic lateral sclerosis (ALS)",4.3967318599482102E-4,1.53941269931858E-2,"MAPK11;MAPK12;RAB5A;PPP3CB"]
["GO:0007409","axonogenesis",4.5671552705467102E-4,1.5890253431864398E-2,"ABL1;ARHGDIA;ATOH1;LIMK1;PPP3CB;MAPK3;SYNGAP1;NRXN3;NRXN1;CYFIP1;PARD3"]
["NCI:103","NCI:IL2_1PATHWAY",4.7240753407774703E-4,1.6333490490738099E-2,"CDK2;MAPK3;MAPK8;MAPK11"]
["GO:0006753","nucleoside phosphate metabolic process",4.8883842891277402E-4,1.6692927091021399E-2,"ABCA1;CBS;FLNA;GALR1;PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0009117","nucleotide metabolic process",4.8883842891277402E-4,1.6692927091021399E-2,"ABCA1;CBS;FLNA;GALR1;PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0006195","purine nucleotide catabolic process",5.2292163552848799E-4,1.77472545260343E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0006357","regulation of transcription from RNA polymerase II promoter",5.3042941428828804E-4,1.7892289755139099E-2,"ABL1;ATOH1;CHD2;ESR2;ETS1;MAPK3;MAPK7;RFX3;SKI;SMARCA2;SOD2;SREBF1;UBE3A;KAT2B;UHRF1;KLF13;EHMT1"]
["REACT:724","REACT: Nuclear Events (kinase and transcription factor activation)",5.4027448933904301E-4,1.81139301516581E-2,"MAPK11;MAPK3;MAPK7"]
["GO:0051049","regulation of transport",5.5973492451985498E-4,1.83885836879767E-2,"ABCA1;ABL1;CACNA1B;CAMK2G;FLNA;PARK2;PIK3CB;PPP3CB;MAPK3;MAPK7;RAB5A;RFX3;IL1RL1;TNK2;PLCB1"]
["GO:0032446","protein modification by small protein conjugation",5.6127744213587197E-4,1.83885836879767E-2,"CDK2;LIMK1;PARK2;PSMB1;PSMC2;UBE3A;TRIP12;TNK2;UBE2W;TICAM1"]
["GO:0072523","purine-containing compound catabolic process",5.6825026083844195E-4,1.83885836879767E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0044427","chromosomal part",5.6825026083844195E-4,1.83885836879767E-2,"CDK2;CDK4;FLNA;RFX3;SMARCA2;TBP;KAT2B;BAZ1B;SMC2;PLCB1;UHRF1"]
["GO:0014069","postsynaptic density",5.6841066714461504E-4,1.83885836879767E-2,"GRID2;DLGAP2;ARHGAP32;SHANK2;ANKS1B"]
["GO:0044327","dendritic spine head",5.6841066714461504E-4,1.83885836879767E-2,"GRID2;DLGAP2;ARHGAP32;SHANK2;ANKS1B"]
["GO:0045859","regulation of protein kinase activity",5.8697760582708904E-4,1.8796481855297299E-2,"ABL1;CBS;CHRNA7;ERCC6;PIK3CB;MAPK3;MAPK11;IKBKG;KAT2B;TAOK2;ZEB2;PARD3"]
["REACT:113","REACT: Antigen processing: Ubiquitination & Proteasome degradation",5.8781477963962996E-4,1.8796481855297299E-2,"CUL2;PARK2;PSMB1;PSMC2;TRIP12;UBE2W;UBE3A"]
["GO:0045595","regulation of cell differentiation",6.0199635056025697E-4,1.9139332248846799E-2,"ABCA1;ABL1;ARHGDIA;ATOH1;ETS1;LIMK1;MAPK11;RFX3;MAPK12;SKI;SOD2;SYNGAP1;PLCB1;KLF13;SMAP1"]
["GO:0030054","cell junction",6.1871373253264501E-4,1.94760494114227E-2,"CHRNA7;DTNA;GRID2;MAPK3;DLGAP2;NRXN1;ARHGAP32;TNK2;SHANK2;RIMS1;CYFIP1;PARD3;ANKS1B"]
["NCI:19","NCI:ATF2_PATHWAY",6.2084561005106703E-4,1.94760494114227E-2,"CDK4;MAPK3;MAPK8;MAPK11"]
["GO:0045944","positive regulation of transcription from RNA polymerase II promoter",6.2314908637415298E-4,1.94760494114227E-2,"ATOH1;ETS1;MAPK3;MAPK7;RFX3;SKI;SMARCA2;SREBF1;UBE3A;KAT2B;UHRF1;KLF13"]
["GO:0045597","positive regulation of cell differentiation",6.3725293379101699E-4,1.9804961964786E-2,"ABL1;ARHGDIA;ATOH1;ETS1;LIMK1;MAPK11;RFX3;MAPK12;PLCB1;SMAP1"]
["GO:0005694","chromosome",6.7098731941773397E-4,2.0736881849267599E-2,"CDK2;CDK4;FLNA;RFX3;SMARCA2;TBP;KAT2B;BAZ1B;SMC2;PLCB1;UHRF1;EHMT1"]
["GO:0019900","kinase binding",6.9139567532927203E-4,2.12488937551196E-2,"ABL1;FLNA;PARK2;PRKAB2;SKI;KAT2B;TAOK2;PARD3;TICAM1"]
["GO:0009166","nucleotide catabolic process",7.1301292384249996E-4,2.1792196103296701E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0048011","nerve growth factor receptor signaling pathway",7.3099722173957998E-4,2.20976865063571E-2,"ARHGDIA;PIK3CB;MAPK3;MAPK7;MAPK8;MAPK11;MAPK12"]
["REACT:1048","REACT: Signalling by NGF",7.3099722173957998E-4,2.20976865063571E-2,"ARHGDIA;MAPK11;MAPK12;MAPK3;MAPK7;MAPK8;PIK3CB"]
["NCI:63","NCI:ERBB1_DOWNSTREAM_PATHWAY",7.4115475299291699E-4,2.2282978769330501E-2,"PIK3CB;MAPK3;MAPK7;MAPK8;RAB5A"]
["REACT:1051","REACT: Signalling to RAS",7.69421960898587E-4,2.2802082498498601E-2,"MAPK11;MAPK12;MAPK3"]
["NCI:182","NCI:RETINOIC_ACID_PATHWAY",7.69421960898587E-4,2.2802082498498601E-2,"MAPK3;MAPK8;KAT2B"]
["GO:0002757","immune response-activating signal transduction",7.7078623051685504E-4,2.2802082498498601E-2,"PIK3CB;MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["GO:0042995","cell projection",7.8749451093979104E-4,2.3172444864462401E-2,"GRID2;LIMK1;MAX;PARK2;MAPK3;RAB5A;RAC3;SYNGAP1;SYNJ2;DLGAP2;TAOK2;NRXN1;ARHGAP32;SHANK2;CYFIP1;SNX9;ANKS1B"]
["GO:0007613","memory",7.9968280292002497E-4,2.3283396135545201E-2,"CHRNA7;PPP3CB;CYP7B1;PLCB1"]
["KEGG:05210","Colorectal cancer",7.9968280292002497E-4,2.3283396135545201E-2,"PIK3CB;MAPK8;RAC3;MAPK3"]
["GO:0045202","synapse",8.1488403719702897E-4,2.3601772218711899E-2,"CHRNA7;DTNA;GRID2;DLGAP2;NRXN1;ARHGAP32;SHANK2;RIMS1;CYFIP1;ANKS1B"]
["GO:0055086","nucleobase-containing small molecule metabolic process",8.56737411622557E-4,2.4684746672374899E-2,"ABCA1;CBS;FLNA;GALR1;PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0048584","positive regulation of response to stimulus",8.7552496399347503E-4,2.47187862354586E-2,"CSNK1D;FLNA;PARK2;PIK3CB;MAPK3;MAPK7;MAPK8;MAPK11;SKI;UBE3A;IKBKG;IL1RL1;TAOK2;ZEB2;PLCB1;TICAM1"]
["GO:0051704","multi-organism process",8.7552496399347503E-4,2.47187862354586E-2,"ABCA1;CBS;ETS1;PPP3CB;MAPK3;PSMB1;PSMC2;SOD2;TBP;UBE3A;CUL2;IKBKG;KAT2B;NRXN1;SYNCRIP;TICAM1"]
["GO:0009203","ribonucleoside triphosphate catabolic process",8.8746544853502904E-4,2.47187862354586E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;SNX9;SMAP1;RALGAPA1"]
["GO:0009207","purine ribonucleoside triphosphate catabolic process",8.8746544853502904E-4,2.47187862354586E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;SNX9;SMAP1;RALGAPA1"]
["GO:0043549","regulation of kinase activity",8.9441586207488703E-4,2.47187862354586E-2,"ABL1;CBS;CHRNA7;ERCC6;PIK3CB;MAPK3;MAPK11;IKBKG;KAT2B;TAOK2;ZEB2;PARD3"]
["GO:0048858","cell projection morphogenesis",8.9441586207488703E-4,2.47187862354586E-2,"ABL1;ARHGDIA;ATOH1;LIMK1;PPP3CB;MAPK3;RFX3;SYNGAP1;NRXN3;NRXN1;CYFIP1;PARD3"]
["GO:0019220","regulation of phosphate metabolic process",8.967989434217E-4,2.47187862354586E-2,"ABL1;CBS;CHRNA7;CSNK1D;ERCC6;PARK2;PIK3CB;MAPK3;MAPK11;IKBKG;KAT2B;TAOK2;ZEB2;TNK2;PARD3"]
["GO:0051174","regulation of phosphorus metabolic process",8.967989434217E-4,2.47187862354586E-2,"ABL1;CBS;CHRNA7;CSNK1D;ERCC6;PARK2;PIK3CB;MAPK3;MAPK11;IKBKG;KAT2B;TAOK2;ZEB2;TNK2;PARD3"]
["GO:0048667","cell morphogenesis involved in neuron differentiation",9.0102564081477696E-4,2.47187862354586E-2,"ABL1;ARHGDIA;ATOH1;LIMK1;PPP3CB;MAPK3;SYNGAP1;NRXN3;NRXN1;CYFIP1;PARD3"]
["GO:0009146","purine nucleoside triphosphate catabolic process",9.0260210042708696E-4,2.47187862354586E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;SNX9;SMAP1;RALGAPA1"]
["GO:0031625","ubiquitin protein ligase binding",9.1282594457690999E-4,2.4728471775899201E-2,"CBS;PARK2;SKI;CUL2;SNX9"]
["GO:0044389","small conjugating protein ligase binding",9.1282594457690999E-4,2.4728471775899201E-2,"CBS;PARK2;SKI;CUL2;SNX9"]
["REACT:975","REACT: S Phase",9.5043436441413505E-4,2.4728471775899201E-2,"CDK2;CDK4;MAX;PSMB1;PSMC2"]
["KEGG:04114","Oocyte meiosis",9.5043436441413505E-4,2.4728471775899201E-2,"MAPK3;CDK2;CAMK2G;PPP3CB;MAPK12"]
["GO:0010506","regulation of autophagy",9.5184632611749901E-4,2.4728471775899201E-2,"ABL1;PARK2;PIK3CB"]
["REACT:178","REACT: CDO in myogenesis",9.5184632611749901E-4,2.4728471775899201E-2,"ABL1;MAPK11;MAPK12"]
["REACT:668","REACT: Myogenesis",9.5184632611749901E-4,2.4728471775899201E-2,"ABL1;MAPK11;MAPK12"]
["GO:0000502","proteasome complex",9.5569661660931701E-4,2.4728471775899201E-2,"PSMB1;PSMC2;UBE3A;TRIP12"]
["REACT:264","REACT: Cyclin E associated events during G1/S transition",9.5569661660931701E-4,2.4728471775899201E-2,"CDK2;MAX;PSMB1;PSMC2"]
["KEGG:05214","Glioma",9.5569661660931701E-4,2.4728471775899201E-2,"CAMK2G;MAPK3;PIK3CB;CDK4"]
["GO:0009143","nucleoside triphosphate catabolic process",9.6529125936038697E-4,2.4728471775899201E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;SNX9;SMAP1;RALGAPA1"]
["GO:0009154","purine ribonucleotide catabolic process",9.6529125936038697E-4,2.4728471775899201E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;SNX9;SMAP1;RALGAPA1"]
["GO:0030425","dendrite",9.65497225066415E-4,2.4728471775899201E-2,"GRID2;MAX;SYNGAP1;DLGAP2;TAOK2;ARHGAP32;SHANK2;ANKS1B"]
["GO:0002764","immune response-regulating signaling pathway",9.7157605522446902E-4,2.4728471775899201E-2,"PIK3CB;MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["GO:0048812","neuron projection morphogenesis",9.7217952074811302E-4,2.4728471775899201E-2,"ABL1;ARHGDIA;ATOH1;LIMK1;PPP3CB;MAPK3;SYNGAP1;NRXN3;NRXN1;CYFIP1;PARD3"]
["GO:0022402","cell cycle process",9.74477015030013E-4,2.4728471775899201E-2,"ABL1;CDK2;CDK4;CSNK1D;FLNA;PRKAB2;PSMB1;PSMC2;MAPK12;CUL2;KAT2B;TAOK2;SMC2;PLCB1;CEP70;TUBGCP5"]
["GO:0045211","postsynaptic membrane",9.8118482159118003E-4,2.4784997411152501E-2,"CHRNA7;GRID2;DLGAP2;ARHGAP32;SHANK2;ANKS1B"]
["GO:0009261","ribonucleotide catabolic process",9.9795335413649096E-4,2.5093990704922998E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;SNX9;SMAP1;RALGAPA1"]
["REACT:261","REACT: Cyclin A:Cdk2-associated events at S phase entry",1.01213930486918E-3,2.51178989971843E-2,"CDK2;MAX;PSMB1;PSMC2"]
["NCI:208","NCI:TELOMERASEPATHWAY",1.01213930486918E-3,2.51178989971843E-2,"ABL1;MAX;MAPK3;UBE3A"]
["GO:0032990","cell part morphogenesis",1.01360523677999E-3,2.51178989971843E-2,"ABL1;ARHGDIA;ATOH1;LIMK1;PPP3CB;MAPK3;RFX3;SYNGAP1;NRXN3;NRXN1;CYFIP1;PARD3"]
["GO:0034655","nucleobase-containing compound catabolic process",1.0170660476083301E-3,2.51178989971843E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0044419","interspecies interaction between organisms",1.03386068072704E-3,2.54191879368088E-2,"MAPK3;PSMB1;PSMC2;TBP;UBE3A;CUL2;IKBKG;KAT2B;SYNCRIP"]
["GO:0045646","regulation of erythrocyte differentiation",1.05245867119182E-3,2.57619529603237E-2,"ETS1;KLF13;SMAP1"]
["GO:0080135","regulation of cellular response to stress",1.0730889693534101E-3,2.6151225455784299E-2,"ABL1;CBS;ERCC6;MAPK3;TAOK2;ZEB2;PLCB1"]
["GO:0048666","neuron development",1.0898923998953699E-3,2.6444231386934899E-2,"ABL1;ARHGDIA;ATOH1;LIMK1;PPP3CB;MAPK3;RAC3;SOD2;SYNGAP1;NRXN3;NRXN1;CYFIP1;PARD3"]
["GO:0031175","neuron projection development",1.1002139677853699E-3,2.6578094627898001E-2,"ABL1;ARHGDIA;ATOH1;LIMK1;PPP3CB;MAPK3;RAC3;SYNGAP1;NRXN3;NRXN1;CYFIP1;PARD3"]
["GO:0051338","regulation of transferase activity",1.1304201618232701E-3,2.7108838417048101E-2,"ABL1;CBS;CHRNA7;ERCC6;PIK3CB;MAPK3;MAPK11;IKBKG;KAT2B;TAOK2;ZEB2;PARD3"]
["KEGG:05120","Epithelial cell signaling in Helicobacter pylori infection",1.1319851182823801E-3,2.7108838417048101E-2,"MAPK11;MAPK12;MAPK8;IKBKG"]
["KEGG:05164","Influenza A",1.1406293889790399E-3,2.7198111119965802E-2,"TICAM1;PIK3CB;MAPK11;MAPK12;MAPK8;MAPK3"]
["GO:0006898","receptor-mediated endocytosis",1.1560244690385099E-3,2.74129875802131E-2,"PIK3CB;MAPK3;RAB5A;TNK2;SNX9"]
["REACT:686","REACT: NOD1/2 Signaling Pathway",1.1595515353886199E-3,2.74129875802131E-2,"IKBKG;MAPK11;MAPK12"]
["GO:0050905","neuromuscular process",1.1954892967494201E-3,2.8142326764331E-2,"GRID2;PARK2;RAC3;NRXN1"]
["GO:0030811","regulation of nucleotide catabolic process",1.2408157374609601E-3,2.89628382263039E-2,"RAP1GDS1;SYNGAP1;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0033121","regulation of purine nucleotide catabolic process",1.2408157374609601E-3,2.89628382263039E-2,"RAP1GDS1;SYNGAP1;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["KEGG:04720","Long-term potentiation",1.26144829411559E-3,2.9320722533812699E-2,"CAMK2G;PPP3CB;MAPK3;PLCB1"]
["GO:0007267","cell-cell signaling",1.2774877259614E-3,2.95692974896169E-2,"CACNA1B;CAMK2G;CHRNA7;DTNA;ESR2;GRID2;PARK2;PPP3CB;RFX3;SYNGAP1;DLGAP2;NRXN1;RIMS1;PLCB1;NTSR2;KCNH8"]
["GO:0030030","cell projection organization",1.3054908758889699E-3,3.00915646892407E-2,"ABL1;ARHGDIA;ATOH1;LIMK1;PPP3CB;MAPK3;RAB5A;RAC3;RFX3;SYNGAP1;NRXN3;NRXN1;CYFIP1;PARD3"]
["KEGG:04622","RIG-I-like receptor signaling pathway",1.32991251831185E-3,3.0527286519921801E-2,"IKBKG;MAPK8;MAPK11;MAPK12"]
["GO:0046328","regulation of JNK cascade",1.34286315425524E-3,3.0697185823719001E-2,"CBS;ERCC6;TAOK2;ZEB2;PLCB1"]
["GO:0008094","DNA-dependent ATPase activity",1.40093230383717E-3,3.1892829237972098E-2,"CHD2;ERCC6;SMARCA2;CHD1L"]
["GO:0005096","GTPase activator activity",1.46177703450629E-3,3.3017134656508497E-2,"ARHGDIA;RAP1GDS1;SYNGAP1;ARHGAP32;PLCB1;SMAP1;RALGAPA1"]
["GO:0046700","heterocycle catabolic process",1.4622556021049501E-3,3.3017134656508497E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0044270","cellular nitrogen compound catabolic process",1.50388535382572E-3,3.3819080395788202E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0008289","lipid binding",1.51184176613804E-3,3.3860358907998399E-2,"ABCA1;DBI;ESR2;PCYT1A;SH3GL3;ARHGAP32;PLCB1;SNX9;PARD3;SNX14"]
["GO:0060627","regulation of vesicle-mediated transport",1.5609913235095599E-3,3.4778203153498902E-2,"ABL1;PIK3CB;MAPK3;RAB5A;TNK2;PLCB1"]
["GO:0016570","histone modification",1.5653963458462099E-3,3.4778203153498902E-2,"CDK2;MAPK3;MAPK8;SKI;KAT2B;BAZ1B;EHMT1"]
["GO:0045860","positive regulation of protein kinase activity",1.58210739879523E-3,3.5008872520540898E-2,"CHRNA7;ERCC6;PIK3CB;MAPK3;MAPK11;IKBKG;TAOK2;ZEB2;PARD3"]
["GO:0070647","protein modification by small protein conjugation or removal",1.6318472211448499E-3,3.59656526986986E-2,"CDK2;LIMK1;PARK2;PSMB1;PSMC2;UBE3A;TRIP12;TNK2;UBE2W;TICAM1"]
["REACT:236","REACT: Class I MHC mediated antigen processing & presentation",1.6746629761451601E-3,3.67628396191867E-2,"CUL2;PARK2;PSMB1;PSMC2;TRIP12;UBE2W;UBE3A"]
["GO:0007270","neuron-neuron synaptic transmission",1.7115704090426699E-3,3.7424535584284699E-2,"GRID2;PARK2;DLGAP2;NRXN1"]
["REACT:210","REACT: Cell Cycle, Mitotic",1.73224063036752E-3,3.7727382548004403E-2,"CDK2;CDK4;CEP70;CSNK1D;MAX;PSMB1;PSMC2;TUBGCP5"]
["KEGG:04062","Chemokine signaling pathway",1.7399754165331599E-3,3.7747231389260602E-2,"PIK3CB;PLCB1;CRKL;PARD3;MAPK3;IKBKG"]
["KEGG:04360","Axon guidance",1.7822342990845301E-3,3.85129693067797E-2,"MAPK3;RAC3;PPP3CB;ABL1;LIMK1"]
["GO:0016569","covalent chromatin modification",1.78978516203592E-3,3.8525647923668201E-2,"CDK2;MAPK3;MAPK8;SKI;KAT2B;BAZ1B;EHMT1"]
["REACT:1050","REACT: Signalling to ERKs",1.7975236649101099E-3,3.8542251605746897E-2,"MAPK11;MAPK12;MAPK3"]
["GO:0042592","homeostatic process",1.8800464417050499E-3,4.0156049866843103E-2,"ABCA1;CACNA1B;CHRNA7;ETS1;GRID2;PIK3CB;PPP3CB;SKI;SOD2;IKBKG;LARGE;NRXN1;NTSR2;KLF13;STEAP3;SMAP1"]
["GO:0042391","regulation of membrane potential",1.9341486443193699E-3,4.11527319245183E-2,"CACNA1B;GRID2;SKI;SOD2;NRXN1;NTSR2"]
["GO:0048699","generation of neurons",1.9611845838425701E-3,4.1568096236847103E-2,"ABL1;ARHGDIA;ATOH1;ESR2;LIMK1;PPP3CB;MAPK3;RAC3;SKI;SOD2;SYNGAP1;NRXN3;NRXN1;CYFIP1;PARD3"]
["GO:0000084","S phase of mitotic cell cycle",1.97144832376886E-3,4.1626153156829597E-2,"ABL1;CDK2;CDK4;PSMB1;PSMC2"]
["GO:0044456","synapse part",2.0118958081919401E-3,4.23186601175582E-2,"CHRNA7;GRID2;DLGAP2;NRXN1;ARHGAP32;SHANK2;RIMS1;ANKS1B"]
["GO:0009205","purine ribonucleoside triphosphate metabolic process",2.0689641149668199E-3,4.3354202590895702E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;SNX9;SMAP1;RALGAPA1"]
["GO:0016568","chromatin modification",2.0963872715747999E-3,4.3576734068081602E-2,"CDK2;MAPK3;MAPK8;SKI;SMARCA2;KAT2B;BAZ1B;CHD1L;EHMT1"]
["GO:0009199","ribonucleoside triphosphate metabolic process",2.0991516528988002E-3,4.3576734068081602E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;SNX9;SMAP1;RALGAPA1"]
["NCI:70","NCI:ER_NONGENOMIC_PATHWAY",2.1032154729171701E-3,4.3576734068081602E-2,"ESR2;MAPK11;PLCB1"]
["GO:0043197","dendritic spine",2.1749613460992898E-3,4.4562541357856603E-2,"GRID2;DLGAP2;ARHGAP32;SHANK2;ANKS1B"]
["GO:0044309","neuron spine",2.1749613460992898E-3,4.4562541357856603E-2,"GRID2;DLGAP2;ARHGAP32;SHANK2;ANKS1B"]
["REACT:650","REACT: Mitotic G1-G1/S phases",2.1749613460992898E-3,4.4562541357856603E-2,"CDK2;CDK4;MAX;PSMB1;PSMC2"]
["GO:0009144","purine nucleoside triphosphate metabolic process",2.19185839942078E-3,4.4736764442501097E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;SNX9;SMAP1;RALGAPA1"]
["GO:0033674","positive regulation of kinase activity",2.1996384541504502E-3,4.4736764442501097E-2,"CHRNA7;ERCC6;PIK3CB;MAPK3;MAPK11;IKBKG;TAOK2;ZEB2;PARD3"]
["REACT:683","REACT: NGF signalling via TRKA from the plasma membrane",2.2460844165233199E-3,4.5514062242516501E-2,"MAPK11;MAPK12;MAPK3;MAPK7;PIK3CB"]
["NCI:181","NCI:REG_GR_PATHWAY",2.2626802088163101E-3,4.5612270277354497E-2,"MAPK3;MAPK8;MAPK11;TBP"]
["GO:0035249","synaptic transmission, glutamatergic",2.26742124480703E-3,4.5612270277354497E-2,"GRID2;PARK2;NRXN1"]
["KEGG:04510","Focal adhesion",2.3129558565848501E-3,4.6144219434519698E-2,"FLNA;PIK3CB;MAPK3;CRKL;MAPK8;RAC3"]
["GO:0042770","signal transduction in response to DNA damage",2.3188888291389201E-3,4.6144219434519698E-2,"ABL1;CDK2;ERCC6;PSMB1;PSMC2"]
["KEGG:04120","Ubiquitin mediated proteolysis",2.3188888291389201E-3,4.6144219434519698E-2,"UBE2W;CUL2;PARK2;UBE3A;TRIP12"]
["GO:0016192","vesicle-mediated transport",2.4508387431683202E-3,4.8595125187122501E-2,"ABCA1;ABL1;FLNA;PIK3CB;PPP3CB;MAPK3;RAB5A;SH3GL3;UBE3A;TNK2;RER1;RIMS1;PLCB1;SNX9"]
["GO:0009141","nucleoside triphosphate metabolic process",2.52505006274679E-3,4.9533535935048903E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;SNX9;SMAP1;RALGAPA1"]
["GO:0007417","central nervous system development",2.5314915469131401E-3,4.9533535935048903E-2,"ATOH1;CBS;ESR2;ETS1;PARK2;SH3GL3;SKI;UBE3A;SYNJ2;ZEB2;PLCB1"]
["GO:0051347","positive regulation of transferase activity",2.5339824059325499E-3,4.9533535935048903E-2,"CHRNA7;ERCC6;PIK3CB;MAPK3;MAPK11;IKBKG;TAOK2;ZEB2;PARD3"]
["GO:0030695","GTPase regulator activity",2.5339824059325499E-3,4.9533535935048903E-2,"ARHGDIA;RAP1GDS1;SYNGAP1;ARHGAP32;TNK2;RIMS1;PLCB1;SMAP1;RALGAPA1"]
["GO:0045088","regulation of innate immune response",2.5531337998397799E-3,4.9732169650400199E-2,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["GO:0007420","brain development",2.5734987228456302E-3,4.98930676375616E-2,"ATOH1;CBS;ESR2;ETS1;SKI;UBE3A;SYNJ2;ZEB2;PLCB1"]
["GO:0051147","regulation of muscle cell differentiation",2.5794319132940399E-3,4.98930676375616E-2,"ABL1;MAPK11;MAPK12;PLCB1"]
["GO:0051320","S phase",2.6273850063395802E-3,5.0643532596064599E-2,"ABL1;CDK2;CDK4;PSMB1;PSMC2"]
["GO:0045786","negative regulation of cell cycle",2.6949980545630699E-3,5.1766420964732301E-2,"CDK2;ETS1;PRKAB2;PSMB1;PSMC2;MAPK12;CUL2;KAT2B;TAOK2"]
["GO:0035091","phosphatidylinositol binding",2.70894516694084E-3,5.1854272192099503E-2,"ARHGAP32;PLCB1;SNX9;PARD3;SNX14"]
["REACT:651","REACT: Mitotic G2-G2/M phases",2.8067458410036901E-3,5.3178677048727002E-2,"CDK2;CEP70;CSNK1D;TUBGCP5"]
["NCI:44","NCI:CXCR3PATHWAY",2.8069728304823301E-3,5.3178677048727002E-2,"PIK3CB;MAPK3;MAPK11"]
["NCI:98","NCI:IFNGPATHWAY",2.8069728304823301E-3,5.3178677048727002E-2,"CAMK2G;CRKL;MAPK3"]
["GO:0000785","chromatin",2.8334904761519301E-3,5.3497847488301997E-2,"CDK4;RFX3;SMARCA2;TBP;BAZ1B;PLCB1;UHRF1"]
["GO:0009150","purine ribonucleotide metabolic process",2.93745394778286E-3,5.5272092650118301E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;SNX9;SMAP1;RALGAPA1"]
["GO:0002682","regulation of immune system process",3.0144216881062701E-3,5.6497269112415302E-2,"ETS1;PIK3CB;PPP3CB;MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;IL1RL1;PLCB1;KLF13;SMAP1;TICAM1"]
["GO:0060589","nucleoside-triphosphatase regulator activity",3.0413931794846701E-3,5.6497269112415302E-2,"ARHGDIA;RAP1GDS1;SYNGAP1;ARHGAP32;TNK2;RIMS1;PLCB1;SMAP1;RALGAPA1"]
["KEGG:04540","Gap junction",3.0474215301861201E-3,5.6497269112415302E-2,"CSNK1D;MAPK7;MAPK3;PLCB1"]
["KEGG:05215","Prostate cancer",3.0474215301861201E-3,5.6497269112415302E-2,"CDK2;IKBKG;PIK3CB;MAPK3"]
["GO:0000086","G2/M transition of mitotic cell cycle",3.0536304165965601E-3,5.6497269112415302E-2,"CDK2;CSNK1D;PLCB1;CEP70;TUBGCP5"]
["KEGG:04810","Regulation of actin cytoskeleton",3.0892584503974798E-3,5.6704394880521002E-2,"CYFIP1;LIMK1;RAC3;MAPK3;PIK3CB;CRKL"]
["GO:0019725","cellular homeostasis",3.0916758347851402E-3,5.6704394880521002E-2,"CACNA1B;CHRNA7;GRID2;PIK3CB;PPP3CB;SKI;SOD2;LARGE;NRXN1;NTSR2;STEAP3"]
["GO:0046483","heterocycle metabolic process",3.0955761485750798E-3,5.6704394880521002E-2,"ABCA1;CBS;FLNA;GALR1;PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0006511","ubiquitin-dependent protein catabolic process",3.1215040876654298E-3,5.6990629085693599E-2,"CDK2;CSNK1D;PARK2;PSMB1;PSMC2;UBE3A;CUL2;TRIP12"]
["GO:0006338","chromatin remodeling",3.1728878648155799E-3,5.7572103092508299E-2,"SMARCA2;KAT2B;BAZ1B;CHD1L"]
["GO:0006184","GTP catabolic process",3.1741669275515199E-3,5.7572103092508299E-2,"RAB5A;RAC3;RAP1GDS1;SYNGAP1;PLCB1;SNX9;SMAP1;RALGAPA1"]
["NCI:184","NCI:RHOA_PATHWAY",3.2069621918541101E-3,5.7976845899793898E-2,"LIMK1;MAPK8;MAPK12"]
["GO:0060341","regulation of cellular localization",3.2268616202822701E-3,5.8146574864499999E-2,"FLNA;PARK2;PPP3CB;MAPK3;MAPK7;RAB5A;RFX3;IL1RL1;NRXN1;PLCB1"]
["GO:0002253","activation of immune response",3.2482057733374198E-3,5.8341150448385101E-2,"PIK3CB;MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["GO:0008629","induction of apoptosis by intracellular signals",3.3018354702521301E-3,5.9112471914028401E-2,"ABL1;ERCC6;MAPK8;CUL2"]
["GO:0043547","positive regulation of GTPase activity",3.3321653182521202E-3,5.9463027550228198E-2,"RAP1GDS1;SYNGAP1;PLCB1;SNX9;RALGAPA1"]
["GO:0009259","ribonucleotide metabolic process",3.3576710340484802E-3,5.9725518200502301E-2,"PSMC2;RAB5A;RAC3;RAP1GDS1;SYNGAP1;CHD1L;PLCB1;SNX9;SMAP1;RALGAPA1"]
["GO:0043087","regulation of GTPase activity",3.3869261128267598E-3,6.0026430383671003E-2,"RAP1GDS1;SYNGAP1;PLCB1;SNX9;SMAP1;RALGAPA1"]
["GO:0022008","neurogenesis",3.3964020586911398E-3,6.0026430383671003E-2,"ABL1;ARHGDIA;ATOH1;ESR2;LIMK1;PPP3CB;MAPK3;RAC3;SKI;SOD2;SYNGAP1;NRXN3;NRXN1;CYFIP1;PARD3"]
["GO:0032940","secretion by cell",3.4071401193913001E-3,6.0026430383671003E-2,"ABCA1;CAMK2G;FLNA;PARK2;PPP3CB;RAB5A;RFX3;IL1RL1;RIMS1;PLCB1;STEAP3"]
["GO:0043408","regulation of MAPK cascade",3.4395263733178502E-3,6.04046345942678E-2,"CBS;ERCC6;MAPK3;SYNGAP1;TAOK2;ZEB2;PLCB1"]
["GO:0019941","modification-dependent protein catabolic process",3.5048622217561899E-3,6.1174173764773902E-2,"CDK2;CSNK1D;PARK2;PSMB1;PSMC2;UBE3A;CUL2;TRIP12"]
["GO:0048872","homeostasis of number of cells",3.5277394234707999E-3,6.1174173764773902E-2,"ETS1;PPP3CB;IKBKG;KLF13;SMAP1"]
["KEGG:04310","Wnt signaling pathway",3.5277394234707999E-3,6.1174173764773902E-2,"PPP3CB;CAMK2G;PLCB1;MAPK8;RAC3"]
["GO:0000904","cell morphogenesis involved in differentiation",3.5319221890772298E-3,6.1174173764773902E-2,"ABL1;ARHGDIA;ATOH1;LIMK1;PPP3CB;MAPK3;SYNGAP1;NRXN3;NRXN1;CYFIP1;PARD3"]
["GO:0055082","cellular chemical homeostasis",3.5386362264511299E-3,6.1174173764773902E-2,"CACNA1B;CHRNA7;GRID2;PIK3CB;PPP3CB;SKI;SOD2;NRXN1;NTSR2;STEAP3"]
["GO:0007050","cell cycle arrest",3.5624888361961101E-3,6.1394667420052597E-2,"CDK2;PRKAB2;PSMB1;PSMC2;MAPK12;CUL2;KAT2B;TAOK2"]
["GO:0033124","regulation of GTP catabolic process",3.62384264424182E-3,6.1962100256168703E-2,"RAP1GDS1;SYNGAP1;PLCB1;SNX9;SMAP1;RALGAPA1"]
["GO:0017156","calcium ion-dependent exocytosis",3.6402173867054999E-3,6.1962100256168703E-2,"PPP3CB;RIMS1;PLCB1"]
["GO:0030850","prostate gland development",3.6402173867054999E-3,6.1962100256168703E-2,"ESR2;UBE3A;CYP7B1"]
["GO:0031056","regulation of histone modification",3.6402173867054999E-3,6.1962100256168703E-2,"MAPK3;MAPK8;SKI"]
["GO:0043632","modification-dependent macromolecule catabolic process",3.6799501908872101E-3,6.2295859961290202E-2,"CDK2;CSNK1D;PARK2;PSMB1;PSMC2;UBE3A;CUL2;TRIP12"]
["GO:0000278","mitotic cell cycle",3.6823474705968699E-3,6.2295859961290202E-2,"ABL1;CDK2;CDK4;CSNK1D;FLNA;PSMB1;PSMC2;CUL2;SMC2;PLCB1;CEP70;TUBGCP5"]
["GO:0051438","regulation of ubiquitin-protein ligase activity",3.7100277757307798E-3,6.2572785534581302E-2,"CDK2;LIMK1;PSMB1;PSMC2"]
["GO:0046039","GTP metabolic process",3.80039759433659E-3,6.3902126115106497E-2,"RAB5A;RAC3;RAP1GDS1;SYNGAP1;PLCB1;SNX9;SMAP1;RALGAPA1"]
["GO:0051098","regulation of binding",3.8363934344142702E-3,6.42838429718431E-2,"MAPK3;MAPK8;SKI;UHRF1;TICAM1"]
["REACT:869","REACT: RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription",3.85336077203699E-3,6.42838429718431E-2,"ERCC6;KAT2B;MAPK3;TBP"]
["GO:0006281","DNA repair",3.8617568385778999E-3,6.42838429718431E-2,"ABL1;CDK2;CSNK1D;ERCC6;BAZ1B;CHD1L;SMC2;UHRF1"]
["GO:0004715","non-membrane spanning protein tyrosine kinase activity",3.8695805693463002E-3,6.42838429718431E-2,"ABL1;BAZ1B;TNK2"]
["GO:0005543","phospholipid binding",3.9586560699057796E-3,6.5566722690774806E-2,"ABCA1;ARHGAP32;PLCB1;SNX9;PARD3;SNX14"]
["NCI:9","NCI:ANGIOPOIETINRECEPTOR_PATHWAY",4.1075669040133598E-3,6.7830030188065396E-2,"ETS1;MAPK3;MAPK8"]
["KEGG:04666","Fc gamma R-mediated phagocytosis",4.1512010212266803E-3,6.8346559670910606E-2,"PIK3CB;MAPK3;CRKL;LIMK1"]
["GO:0000902","cell morphogenesis",4.2316043046581502E-3,6.9463605380916504E-2,"ABL1;ARHGDIA;ATOH1;LIMK1;PPP3CB;MAPK3;RFX3;SYNGAP1;TAOK2;NRXN3;NRXN1;CYFIP1;PARD3"]
["GO:0000209","protein polyubiquitination",4.2774561579729496E-3,6.9802027923027601E-2,"PARK2;PSMB1;PSMC2;UBE3A;UBE2W"]
["GO:0031396","regulation of protein ubiquitination",4.2774561579729496E-3,6.9802027923027601E-2,"CDK2;LIMK1;PSMB1;PSMC2;TICAM1"]
["GO:0051340","regulation of ligase activity",4.3057974028263999E-3,7.0016402074080594E-2,"CDK2;LIMK1;PSMB1;PSMC2"]
["GO:0042692","muscle cell differentiation",4.3159062016018598E-3,7.0016402074080594E-2,"ABL1;MAPK11;MAPK12;SKI;SMARCA2;PLCB1"]
["GO:0000186","activation of MAPKK activity",4.3542720537922503E-3,7.0254803837130494E-2,"ERCC6;MAPK3;TAOK2"]
["GO:0030163","protein catabolic process",4.3560010332855696E-3,7.0254803837130494E-2,"CDK2;CSNK1D;FLNA;PARK2;PSMB1;PSMC2;UBE3A;CUL2;TRIP12"]
["GO:0002820","negative regulation of adaptive immune response",4.4447751403088797E-3,7.0930811847648101E-2,"PPP3CB;IL1RL1"]
["GO:0043330","response to exogenous dsRNA",4.4447751403088797E-3,7.0930811847648101E-2,"MAPK3;TICAM1"]
["GO:0045648","positive regulation of erythrocyte differentiation",4.4447751403088797E-3,7.0930811847648101E-2,"ETS1;SMAP1"]
["GO:0051603","proteolysis involved in cellular protein catabolic process",4.4492031292722098E-3,7.0930811847648101E-2,"CDK2;CSNK1D;PARK2;PSMB1;PSMC2;UBE3A;CUL2;TRIP12"]
["GO:0051318","G1 phase",4.6097886100715203E-3,7.2653420486939096E-2,"CDK2;CDK4;PLCB1"]
["REACT:177","REACT: CDK-mediated phosphorylation and removal of Cdc6",4.6097886100715203E-3,7.2653420486939096E-2,"CDK2;PSMB1;PSMC2"]
["REACT:1208","REACT: Ubiquitin-dependent degradation of Cyclin D",4.6097886100715203E-3,7.2653420486939096E-2,"CDK4;PSMB1;PSMC2"]
["REACT:1209","REACT: Ubiquitin-dependent degradation of Cyclin D1",4.6097886100715203E-3,7.2653420486939096E-2,"CDK4;PSMB1;PSMC2"]
["GO:0006917","induction of apoptosis",4.7314168140260198E-3,7.4358516520431697E-2,"ABL1;ERCC6;ETS1;PPP3CB;MAPK8;CUL2;IKBKG;TICAM1"]
["GO:2000026","regulation of multicellular organismal development",4.83561924575804E-3,7.5780865913692499E-2,"ARHGDIA;ATOH1;CHRNA7;ETS1;LIMK1;MAPK7;MAPK8;RFX3;SKI;SYNGAP1;NRXN1;PLCB1;KLF13;SMAP1"]
["REACT:730","REACT: Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways",4.8742061377404899E-3,7.6008028112253406E-2,"IKBKG;MAPK11;MAPK12"]
["GO:0012502","induction of programmed cell death",4.8775939949114097E-3,7.6008028112253406E-2,"ABL1;ERCC6;ETS1;PPP3CB;MAPK8;CUL2;IKBKG;TICAM1"]
["GO:0032365","intracellular lipid transport",5.05753576159668E-3,7.7717466203202301E-2,"ABCA1;PRKAB2"]
["GO:0046716","muscle cell homeostasis",5.05753576159668E-3,7.7717466203202301E-2,"PPP3CB;LARGE"]
["GO:0016892","endoribonuclease activity, producing 3'-phosphomonoesters",5.05753576159668E-3,7.7717466203202301E-2,"RNASE1;RNASE6"]
["GO:0048365","Rac GTPase binding",5.05753576159668E-3,7.7717466203202301E-2,"FLNA;CYFIP1"]
["REACT:580","REACT: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1",5.05753576159668E-3,7.7717466203202301E-2,"IKBKG;MAPK8"]
["NCI:18","NCI:AR_TF_PATHWAY",5.1476112198735897E-3,7.8664600188786404E-2,"MAPK8;SMARCA2;KAT2B"]
["NCI:127","NCI:KITPATHWAY",5.1476112198735897E-3,7.8664600188786404E-2,"CRKL;MAPK3;MAPK8"]
["GO:0044257","cellular protein catabolic process",5.1803517983274603E-3,7.89468488935193E-2,"CDK2;CSNK1D;PARK2;PSMB1;PSMC2;UBE3A;CUL2;TRIP12"]
["GO:0010647","positive regulation of cell communication",5.3366657428943901E-3,8.1105590356295998E-2,"CSNK1D;FLNA;PARK2;SKI;UBE3A;IKBKG;TAOK2;NRXN1;ZEB2;PLCB1;TICAM1"]
["REACT:863","REACT: RNA Polymerase I Promoter Clearance",5.4300875019062996E-3,8.2299298796015496E-2,"ERCC6;KAT2B;MAPK3"]
["GO:0051090","regulation of sequence-specific DNA binding transcription factor activity",5.4796248680754603E-3,8.28231824322226E-2,"ESR2;FLNA;MAPK3;MAPK8;MAPK11;IKBKG;TICAM1"]
["GO:0023056","positive regulation of signaling",5.6982673769895098E-3,8.4859333640010207E-2,"CSNK1D;FLNA;PARK2;SKI;UBE3A;IKBKG;TAOK2;NRXN1;ZEB2;PLCB1;TICAM1"]
["GO:0000303","response to superoxide",5.7068286169214997E-3,8.4859333640010207E-2,"ERCC6;SOD2"]
["GO:0000307","cyclin-dependent protein kinase holoenzyme complex",5.7068286169214997E-3,8.4859333640010207E-2,"CDK2;CDK4"]
["REACT:1246","REACT: activated TAK1 mediates p38 MAPK activation",5.7068286169214997E-3,8.4859333640010207E-2,"IKBKG;MAPK11"]
["KEGG:05223","Non-small cell lung cancer",5.7217157353079903E-3,8.4859333640010207E-2,"PIK3CB;CDK4;MAPK3"]
["NCI:143","NCI:NFAT_3PATHWAY",5.7217157353079903E-3,8.4859333640010207E-2,"PPP3CB;MAPK3;MAPK8"]
["NCI:174","NCI:RAC1_PATHWAY",5.7217157353079903E-3,8.4859333640010207E-2,"ARHGDIA;LIMK1;MAPK8"]
["REACT:866","REACT: RNA Polymerase I Transcription",6.0225738207561304E-3,8.9082562503804599E-2,"ERCC6;KAT2B;MAPK3"]
["GO:0043122","regulation of I-kappaB kinase/NF-kappaB cascade",6.1072380145667403E-3,9.0093975190888603E-2,"FLNA;PARK2;IKBKG;IL1RL1;TICAM1"]
["REACT:421","REACT: G1/S Transition",6.2694219678707799E-3,9.1995868239419507E-2,"CDK2;MAX;PSMB1;PSMC2"]
["REACT:1030","REACT: Signaling by Interleukins",6.2694219678707799E-3,9.1995868239419507E-2,"CRKL;IKBKG;MAPK3;PIK3CB"]
["REACT:978","REACT: SCF(Skp2)-mediated degradation of p27/p21",6.3327368508174003E-3,9.2547482933466305E-2,"CDK2;PSMB1;PSMC2"]
["REACT:208","REACT: Cell Cycle",6.3548219114993101E-3,9.2547482933466305E-2,"CDK2;CDK4;CEP70;CSNK1D;MAX;PSMB1;PSMC2;TUBGCP5"]
["GO:0000305","response to oxygen radical",6.3921439260614197E-3,9.2547482933466305E-2,"ERCC6;SOD2"]
["GO:0033144","negative regulation of intracellular steroid hormone receptor signaling pathway",6.3921439260614197E-3,9.2547482933466305E-2,"ESR2;CYP7B1"]
["REACT:939","REACT: Regulation of signaling by CBL",6.3921439260614197E-3,9.2547482933466305E-2,"CRKL;PIK3CB"]
["GO:0031400","negative regulation of protein modification process",6.4073908104695602E-3,9.2547482933466305E-2,"LIMK1;PARK2;PSMB1;PSMC2;SKI"]
["GO:0032989","cellular component morphogenesis",6.5059829259718803E-3,9.3726816527282403E-2,"ABL1;ARHGDIA;ATOH1;LIMK1;PPP3CB;MAPK3;RFX3;SYNGAP1;TAOK2;NRXN3;NRXN1;CYFIP1;PARD3"]
["REACT:1272","REACT: p53-Dependent G1 DNA Damage Response",6.6522771521401397E-3,9.5091465647646603E-2,"CDK2;PSMB1;PSMC2"]
["REACT:1273","REACT: p53-Dependent G1/S DNA damage checkpoint",6.6522771521401397E-3,9.5091465647646603E-2,"CDK2;PSMB1;PSMC2"]
["KEGG:05221","Acute myeloid leukemia",6.6522771521401397E-3,9.5091465647646603E-2,"IKBKG;PIK3CB;MAPK3"]
["GO:0030182","neuron differentiation",6.6869186698309798E-3,9.5340294024497396E-2,"ABL1;ARHGDIA;ATOH1;LIMK1;PPP3CB;MAPK3;RAC3;SOD2;SYNGAP1;NRXN3;NRXN1;CYFIP1;PARD3"]
["REACT:546","REACT: Innate Immune System",6.7891121787062398E-3,9.6548505328028097E-2,"IKBKG;MAPK11;MAPK12;MAPK3;MAPK7;MAPK8;TICAM1"]
["GO:0001726","ruffle",6.8930244923938898E-3,9.7774901261341099E-2,"RAB5A;SYNJ2;CYFIP1;SNX9"]
["GO:0042787","protein ubiquitination involved in ubiquitin-dependent protein catabolic process",6.9812643271631699E-3,9.8521311882312904E-2,"PARK2;UBE3A;TRIP12"]
["NCI:75","NCI:FCER1PATHWAY",6.9812643271631699E-3,9.8521311882312904E-2,"MAPK3;MAPK8;IKBKG"]
["REACT:860","REACT: RIP-mediated NFkB activation via DAI",7.1129770019357202E-3,9.9870529885046702E-2,"IKBKG;TICAM1"]
["REACT:1225","REACT: Viral dsRNA:TLR3:TRIF Complex Activates RIP1",7.1129770019357202E-3,9.9870529885046702E-2,"IKBKG;TICAM1"]
["GO:0051726","regulation of cell cycle",7.1933056406126503E-3,0.100742700769289,"CDK2;CDK4;ETS1;PRKAB2;PSMB1;PSMC2;MAPK12;CUL2;KAT2B;TAOK2;PLCB1"]
["GO:0006873","cellular ion homeostasis",7.5235834671751097E-3,0.105102181162658,"CACNA1B;CHRNA7;GRID2;PIK3CB;SKI;SOD2;NRXN1;NTSR2;STEAP3"]
["GO:0022403","cell cycle phase",7.5978791575020098E-3,0.105872714104033,"ABL1;CDK2;CDK4;CSNK1D;FLNA;PSMB1;PSMC2;CUL2;SMC2;PLCB1;CEP70;TUBGCP5"]
["GO:0048145","regulation of fibroblast proliferation",7.6678443339238903E-3,0.10604628713816699,"CDK4;SKI;SOD2"]
["REACT:420","REACT: G1/S DNA Damage Checkpoints",7.6678443339238903E-3,0.10604628713816699,"CDK2;PSMB1;PSMC2"]
["NCI:216","NCI:TRKRPATHWAY",7.6678443339238903E-3,0.10604628713816699,"ABL1;CRKL;MAPK3"]
["GO:0045022","early endosome to late endosome transport",7.8688282062014201E-3,0.1082844717331,"FLNA;MAPK3"]
["GO:0048147","negative regulation of fibroblast proliferation",7.8688282062014201E-3,0.1082844717331,"SKI;SOD2"]
["GO:0006325","chromatin organization",7.9948515079767794E-3,0.109352841782118,"CDK2;MAPK3;MAPK8;SKI;SMARCA2;KAT2B;BAZ1B;CHD1L;EHMT1"]
["GO:0030177","positive regulation of Wnt receptor signaling pathway",8.0255631181959993E-3,0.109352841782118,"CSNK1D;SKI;ZEB2"]
["GO:0051899","membrane depolarization",8.0255631181959993E-3,0.109352841782118,"CACNA1B;GRID2;NRXN1"]
["KEGG:00562","Inositol phosphate metabolism",8.0255631181959993E-3,0.109352841782118,"SYNJ2;PLCB1;PIK3CB"]
["KEGG:04020","Calcium signaling pathway",8.0650685913059E-3,0.109352841782118,"CAMK2G;PPP3CB;CHRNA7;PLCB1;CACNA1B"]
["KEGG:05168","Herpes simplex infection",8.0650685913059E-3,0.109352841782118,"MAPK8;TICAM1;IKBKG;TBP;CDK2"]
["GO:0017124","SH3 domain binding",8.2605601198532108E-3,0.111729629787354,"ABL1;SYNGAP1;SYNJ2;SHANK2"]
["GO:0050776","regulation of immune response",8.2882635965582999E-3,0.111830912722343,"PIK3CB;PPP3CB;MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;IL1RL1;TICAM1"]
["GO:0048144","fibroblast proliferation",8.3929807613456198E-3,0.11269410090234,"CDK4;SKI;SOD2"]
["NCI:53","NCI:ENDOTHELINPATHWAY",8.3929807613456198E-3,0.11269410090234,"MAPK3;MAPK8;PLCB1"]
["GO:0000082","G1/S transition of mitotic cell cycle",8.4292009415963803E-3,0.11290639130487,"CDK2;CDK4;PSMB1;PSMC2;CUL2"]
["GO:0046903","secretion",8.6322786311723108E-3,0.11459978581725,"ABCA1;CAMK2G;FLNA;PARK2;PPP3CB;RAB5A;RFX3;IL1RL1;RIMS1;PLCB1;STEAP3"]
["GO:0070603","SWI/SNF-type complex",8.6592029052079897E-3,0.11459978581725,"SMARCA2;BAZ1B"]
["GO:0016894","endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters",8.6592029052079897E-3,0.11459978581725,"RNASE1;RNASE6"]
["REACT:269","REACT: Cytosolic sensors of pathogen-associated DNA",8.6592029052079897E-3,0.11459978581725,"IKBKG;TICAM1"]
["REACT:273","REACT: DAI mediated induction of type I IFNs",8.6592029052079897E-3,0.11459978581725,"IKBKG;TICAM1"]
["GO:0072657","protein localization in membrane",8.7701538538028194E-3,0.11579114825593601,"FLNA;SYNGAP1;NRXN1"]
["GO:0048511","rhythmic process",8.8045961618927904E-3,0.115969109446645,"CSNK1D;ESR2;ETS1;UBE3A;CYP7B1"]
["GO:0000228","nuclear chromosome",9.1569971357337403E-3,0.119474714929002,"RFX3;SMARCA2;TBP;BAZ1B;SMC2;PLCB1"]
["GO:0043506","regulation of JUN kinase activity",9.1571365021505206E-3,0.119474714929002,"CBS;ERCC6;ZEB2"]
["GO:0048675","axon extension",9.1571365021505206E-3,0.119474714929002,"LIMK1;PPP3CB;CYFIP1"]
["GO:0051099","positive regulation of binding",9.1571365021505206E-3,0.119474714929002,"SKI;UHRF1;TICAM1"]
["REACT:1181","REACT: Transmission across Chemical Synapses",9.1914210751898508E-3,0.119639862089295,"CACNA1B;CAMK2G;CHRNA7;PLCB1;RIMS1"]
["GO:0050778","positive regulation of immune response",9.5178917263440601E-3,0.12359853762942601,"PIK3CB;MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;TICAM1"]
["GO:0070555","response to interleukin-1",9.5539803675799406E-3,0.123776626214174,"ETS1;MAPK3;PLCB1"]
["GO:0031267","small GTPase binding",9.7951302670719193E-3,0.12660434728374301,"ABCA1;FLNA;RIMS1;CYFIP1"]
["REACT:62","REACT: Activation of NF-kappaB in B Cells",9.9607347038995105E-3,0.12814601019063299,"IKBKG;PSMB1;PSMC2"]
["NCI:158","NCI:P75NTRPATHWAY",9.9607347038995105E-3,0.12814601019063299,"ARHGDIA;MAPK8;IKBKG"]
["GO:0030139","endocytic vesicle",1.00676595503975E-2,0.12922109659582101,"ABCA1;CAMK2G;RAB5A;NRXN1"]
["GO:0048878","chemical homeostasis",1.01885792058862E-2,0.13047041705315399,"ABCA1;CACNA1B;CHRNA7;GRID2;PIK3CB;PPP3CB;SKI;SOD2;NRXN1;NTSR2;STEAP3"]
["NCI:171","NCI:PRLSIGNALINGEVENTSPATHWAY",1.03415690145174E-2,0.13077000787631801,"CDK2;MAPK3"]
["KEGG:04724","Glutamatergic synapse",1.03450681106132E-2,0.13077000787631801,"PLCB1;PPP3CB;MAPK3;SHANK2"]
["GO:0006977","DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest",1.0377446395101899E-2,0.13077000787631801,"CDK2;PSMB1;PSMC2"]
["GO:0072413","signal transduction involved in mitotic cell cycle checkpoint",1.0377446395101899E-2,0.13077000787631801,"CDK2;PSMB1;PSMC2"]
["GO:0072431","signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint",1.0377446395101899E-2,0.13077000787631801,"CDK2;PSMB1;PSMC2"]
["GO:0072474","signal transduction involved in mitotic cell cycle G1/S checkpoint",1.0377446395101899E-2,0.13077000787631801,"CDK2;PSMB1;PSMC2"]
["NCI:36","NCI:CD8TCRDOWNSTREAMPATHWAY",1.0377446395101899E-2,0.13077000787631801,"PPP3CB;MAPK3;MAPK8"]
["GO:0009967","positive regulation of signal transduction",1.06395676673742E-2,0.13376838258162199,"CSNK1D;FLNA;PARK2;SKI;UBE3A;IKBKG;TAOK2;ZEB2;PLCB1;TICAM1"]
["GO:0016887","ATPase activity",1.0686113723708699E-2,0.13401034322527899,"ABCA1;CHD2;ERCC6;PSMC2;SMARCA2;CHD1L;DDX53"]
["GO:0072401","signal transduction involved in DNA integrity checkpoint",1.08041599924936E-2,0.13401034322527899,"CDK2;PSMB1;PSMC2"]
["GO:0072404","signal transduction involved in G1/S transition checkpoint",1.08041599924936E-2,0.13401034322527899,"CDK2;PSMB1;PSMC2"]
["GO:0072422","signal transduction involved in DNA damage checkpoint",1.08041599924936E-2,0.13401034322527899,"CDK2;PSMB1;PSMC2"]
["KEGG:04115","p53 signaling pathway",1.08041599924936E-2,0.13401034322527899,"CDK2;STEAP3;CDK4"]
["NCI:135","NCI:MTOR_4PATHWAY",1.08041599924936E-2,0.13401034322527899,"CDK2;MAPK3;SREBF1"]
["GO:0030234","enzyme regulator activity",1.0867764076195E-2,0.134497697694655,"ARHGDIA;MAPK8;RAP1GDS1;SKI;SYNGAP1;KAT2B;ARHGAP32;ZEB2;TNK2;RIMS1;PLCB1;SMAP1;RALGAPA1"]
["GO:0048585","negative regulation of response to stimulus",1.0971373933775799E-2,0.13547687634296299,"ESR2;GRID2;PPP3CB;MAPK7;SKI;SYNGAP1;IL1RL1;NRXN1;CYP7B1;SNX14"]
["GO:0006361","transcription initiation from RNA polymerase I promoter",1.12325957895337E-2,0.136453679847065,"MAPK3;KAT2B"]
["REACT:867","REACT: RNA Polymerase I Transcription Initiation",1.12325957895337E-2,0.136453679847065,"ERCC6;KAT2B"]
["KEGG:04320","Dorso-ventral axis formation",1.12325957895337E-2,0.136453679847065,"ETS1;MAPK3"]
["NCI:131","NCI:LYMPHANGIOGENESIS_PATHWAY",1.12325957895337E-2,0.136453679847065,"MAPK3;MAPK11"]
["NCI:190","NCI:S1P_S1P2_PATHWAY",1.12325957895337E-2,0.136453679847065,"MAPK3;MAPK8"]
["GO:0072395","signal transduction involved in cell cycle checkpoint",1.1240917751390999E-2,0.136453679847065,"CDK2;PSMB1;PSMC2"]
["KEGG:04920","Adipocytokine signaling pathway",1.1240917751390999E-2,0.136453679847065,"PRKAB2;IKBKG;MAPK8"]
["GO:0007610","behavior",1.12478087509511E-2,0.136453679847065,"CHRNA7;PARK2;PPP3CB;SOD2;SYNGAP1;NRXN1;CYP7B1;PLCB1"]
["GO:0000077","DNA damage checkpoint",1.1504130818035601E-2,0.138953824640552,"CDK2;PSMB1;PSMC2;TAOK2"]
["GO:0000790","nuclear chromatin",1.1504130818035601E-2,0.138953824640552,"RFX3;SMARCA2;TBP;PLCB1"]
["GO:0005667","transcription factor complex",1.15924073192254E-2,0.13971502677550099,"CDK2;CDK4;ETS1;RFX3;SKI;TBP"]
["REACT:738","REACT: Orc1 removal from chromatin",1.16877596673884E-2,0.139949537835482,"CDK2;PSMB1;PSMC2"]
["REACT:1071","REACT: Switching of origins to a post-replicative state",1.16877596673884E-2,0.139949537835482,"CDK2;PSMB1;PSMC2"]
["KEGG:04730","Long-term depression",1.16877596673884E-2,0.139949537835482,"PLCB1;GRID2;MAPK3"]
["GO:0042127","regulation of cell proliferation",1.1743583702195399E-2,0.140314265746318,"BNC1;CDK2;CDK4;CHRNA7;ESR2;ETS1;SKI;SMARCA2;SOD2;CUL2;KAT2B;CYP7B1;KLF13;TICAM1"]
["GO:0000267","cell fraction",1.2136295316279799E-2,0.14430942232080801,"ABCA1;CBS;ERCC6;GRID2;PCYT1A;PPP3CB;MAPK3;MAPK12;SOD2;SYNGAP1;SYNJ2;CYP7B1;SYNCRIP;CYFIP1;PLCB1"]
["KEGG:05218","Melanoma",1.2144723512200599E-2,0.14430942232080801,"CDK4;PIK3CB;MAPK3"]
["GO:0060325","face morphogenesis",1.21562167030905E-2,0.14430942232080801,"SKI;NRXN1"]
["GO:0031347","regulation of defense response",1.22894851316425E-2,0.14526801655608201,"MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;IL1RL1;TICAM1"]
["GO:0005625","soluble fraction",1.22894851316425E-2,0.14526801655608201,"CBS;ERCC6;PCYT1A;PPP3CB;MAPK3;MAPK12;SOD2"]
["REACT:219","REACT: Centrosome maturation",1.2611844869086E-2,0.147815097067339,"CEP70;CSNK1D;TUBGCP5"]
["REACT:897","REACT: Recruitment of mitotic centrosome proteins and complexes",1.2611844869086E-2,0.147815097067339,"CEP70;CSNK1D;TUBGCP5"]
["REACT:949","REACT: Removal of licensing factors from origins",1.2611844869086E-2,0.147815097067339,"CDK2;PSMB1;PSMC2"]
["NCI:48","NCI:E2F_PATHWAY",1.2611844869086E-2,0.147815097067339,"CDK2;SMARCA2;KAT2B"]
["GO:0044463","cell projection part",1.30364209028653E-2,0.151019719432018,"GRID2;RAC3;SYNGAP1;SYNJ2;DLGAP2;NRXN1;ARHGAP32;SHANK2;ANKS1B"]
["GO:0051352","negative regulation of ligase activity",1.30891571678533E-2,0.151019719432018,"LIMK1;PSMB1;PSMC2"]
["GO:0051444","negative regulation of ubiquitin-protein ligase activity",1.30891571678533E-2,0.151019719432018,"LIMK1;PSMB1;PSMC2"]
["GO:0071222","cellular response to lipopolysaccharide",1.30891571678533E-2,0.151019719432018,"ABCA1;MAPK3;TICAM1"]
["KEGG:04520","Adherens junction",1.30891571678533E-2,0.151019719432018,"MAPK3;RAC3;PARD3"]
["NCI:157","NCI:P73PATHWAY",1.30891571678533E-2,0.151019719432018,"ABL1;CDK2;MAPK11"]
["GO:0005546","phosphatidylinositol-4,5-bisphosphate binding",1.3111961496665599E-2,0.151019719432018,"PLCB1;PARD3"]
["NCI:214","NCI:TOLL_ENDOGENOUS_PATHWAY",1.3111961496665599E-2,0.151019719432018,"IKBKG;TICAM1"]
["GO:0044265","cellular macromolecule catabolic process",1.3130962589804901E-2,0.151019719432018,"CDK2;CSNK1D;PARK2;PSMB1;PSMC2;RNASE6;RPL19;UBE3A;CUL2;TRIP12"]
["REACT:708","REACT: Neuronal System",1.3381134833316001E-2,0.15335467164173699,"CACNA1B;CAMK2G;CHRNA7;KCNH8;PLCB1;RIMS1"]
["GO:0044092","negative regulation of molecular function",1.338942632013E-2,0.15335467164173699,"ABL1;FLNA;GALR1;LIMK1;MAPK3;MAPK8;PSMB1;PSMC2;SKI;KAT2B"]
["GO:0007249","I-kappaB kinase/NF-kappaB cascade",1.34670412903796E-2,0.15392494301318199,"FLNA;PARK2;IKBKG;IL1RL1;TICAM1"]
["GO:0031571","mitotic cell cycle G1/S transition DNA damage checkpoint",1.35766917194565E-2,0.15422229690355899,"CDK2;PSMB1;PSMC2"]
["GO:0030594","neurotransmitter receptor activity",1.35766917194565E-2,0.15422229690355899,"CHRNA7;GALR1;NTSR2"]
["KEGG:05140","Leishmaniasis",1.35766917194565E-2,0.15422229690355899,"MAPK3;MAPK11;MAPK12"]
["GO:0071496","cellular response to external stimulus",1.3723603559156999E-2,0.15498005234095799,"ABCA1;MAX;MAPK3;MAPK8;SREBF1"]
["GO:0021537","telencephalon development",1.37274449832013E-2,0.15498005234095799,"ATOH1;SKI;ZEB2;PLCB1"]
["GO:0031570","DNA integrity checkpoint",1.37274449832013E-2,0.15498005234095799,"CDK2;PSMB1;PSMC2;TAOK2"]
["GO:0050801","ion homeostasis",1.38947340049893E-2,0.15654922304603,"CACNA1B;CHRNA7;GRID2;PIK3CB;SKI;SOD2;NRXN1;NTSR2;STEAP3"]
["REACT:909","REACT: Regulation of DNA replication",1.40744777501826E-2,0.15757108140707701,"CDK2;PSMB1;PSMC2"]
["GO:0006513","protein monoubiquitination",1.4099364659527E-2,0.15757108140707701,"PARK2;UBE2W"]
["GO:0043388","positive regulation of DNA binding",1.4099364659527E-2,0.15757108140707701,"SKI;UHRF1"]
["NCI:112","NCI:IL8CXCR1_PATHWAY",1.4099364659527E-2,0.15757108140707701,"RAB5A;PLCB1"]
["GO:0032880","regulation of protein localization",1.42351358174715E-2,0.15844823207696601,"ARHGDIA;FLNA;MAPK7;MAPK8;IL1RL1;NRXN1"]
["GO:0051248","negative regulation of protein metabolic process",1.42351358174715E-2,0.15844823207696601,"FLNA;LIMK1;PARK2;PSMB1;PSMC2;SKI"]
["GO:0043065","positive regulation of apoptotic process",1.4489876554390499E-2,0.16095983353190399,"ABL1;ERCC6;ESR2;ETS1;PPP3CB;MAPK8;CUL2;IKBKG;TICAM1"]
["KEGG:04650","Natural killer cell mediated cytotoxicity",1.47582388348478E-2,0.163612379227211,"PPP3CB;PIK3CB;MAPK3;RAC3"]
["GO:0008285","negative regulation of cell proliferation",1.47998427080253E-2,0.16374545972159199,"ESR2;ETS1;SKI;SMARCA2;SOD2;CUL2;KAT2B;KLF13"]
["GO:0071219","cellular response to molecule of bacterial origin",1.51009109331178E-2,0.16463107189279999,"ABCA1;MAPK3;TICAM1"]
["REACT:905","REACT: Regulation of APC/C activators between G1/S and early anaphase",1.51009109331178E-2,0.16463107189279999,"CDK2;PSMB1;PSMC2"]
["GO:0030799","regulation of cyclic nucleotide metabolic process",1.5112424348089E-2,0.16463107189279999,"ABCA1;CBS;FLNA;GALR1"]
["GO:0043123","positive regulation of I-kappaB kinase/NF-kappaB cascade",1.5112424348089E-2,0.16463107189279999,"FLNA;PARK2;IKBKG;TICAM1"]
["GO:0007215","glutamate receptor signaling pathway",1.5117965387119001E-2,0.16463107189279999,"GRID2;PLCB1"]
["GO:0046854","phosphatidylinositol phosphorylation",1.5117965387119001E-2,0.16463107189279999,"PIK3CB;SYNJ2"]
["GO:0060079","regulation of excitatory postsynaptic membrane potential",1.5117965387119001E-2,0.16463107189279999,"GRID2;NRXN1"]
["GO:0060740","prostate gland epithelium morphogenesis",1.5117965387119001E-2,0.16463107189279999,"ESR2;CYP7B1"]
["GO:0051276","chromosome organization",1.5164231157103599E-2,0.16481046514950301,"CDK2;MAPK3;MAPK8;SKI;SMARCA2;KAT2B;BAZ1B;CHD1L;SMC2;EHMT1"]
["GO:0043068","positive regulation of programmed cell death",1.5260194538139499E-2,0.16552822781370199,"ABL1;ERCC6;ESR2;ETS1;PPP3CB;MAPK8;CUL2;IKBKG;TICAM1"]
["GO:0051345","positive regulation of hydrolase activity",1.53172846445733E-2,0.16582234570211299,"MAPK8;RAP1GDS1;SYNGAP1;PLCB1;NTSR2;UHRF1;SNX9;RALGAPA1"]
["GO:0051020","GTPase binding",1.54719454837744E-2,0.16716953596921899,"ABCA1;FLNA;RIMS1;CYFIP1"]
["GO:0030218","erythrocyte differentiation",1.56296064166252E-2,0.16788928678984599,"ETS1;KLF13;SMAP1"]
["GO:0048588","developmental cell growth",1.56296064166252E-2,0.16788928678984599,"LIMK1;PPP3CB;CYFIP1"]
["GO:0051439","regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle",1.56296064166252E-2,0.16788928678984599,"CDK2;PSMB1;PSMC2"]
["GO:0044451","nucleoplasm part",1.6040707133463301E-2,0.17037137598923899,"CDK2;CDK4;ERCC6;ETS1;MAX;RFX3;SKI;TBP;KAT2B;PLCB1;ANKS1B"]
["GO:0016575","histone deacetylation",1.6167307539785802E-2,0.17037137598923899,"MAPK8;SKI"]
["GO:0032091","negative regulation of protein binding",1.6167307539785802E-2,0.17037137598923899,"MAPK3;MAPK8"]
["GO:0046834","lipid phosphorylation",1.6167307539785802E-2,0.17037137598923899,"PIK3CB;SYNJ2"]
["GO:0060323","head morphogenesis",1.6167307539785802E-2,0.17037137598923899,"SKI;NRXN1"]
["GO:0070491","repressing transcription factor binding",1.6167307539785802E-2,0.17037137598923899,"SKI;TBP"]
["NCI:153","NCI:P38_MKK3_6PATHWAY",1.6167307539785802E-2,0.17037137598923899,"MAPK11;TAOK2"]
["NCI:180","NCI:REELINPATHWAY",1.6167307539785802E-2,0.17037137598923899,"CRKL;MAPK8"]
["GO:0000216","M/G1 transition of mitotic cell cycle",1.6168650107438599E-2,0.17037137598923899,"CDK2;PSMB1;PSMC2"]
["GO:0043393","regulation of protein binding",1.6168650107438599E-2,0.17037137598923899,"MAPK3;MAPK8;TICAM1"]
["GO:0008134","transcription factor binding",1.6419003791313801E-2,0.17268047333374101,"ETS1;FLNA;SKI;TBP;KAT2B;BAZ1B;TRIP12"]
["GO:0033044","regulation of chromosome organization",1.67180613073366E-2,0.17515968778823099,"MAPK3;MAPK8;SKI"]
["GO:0050768","negative regulation of neurogenesis",1.67180613073366E-2,0.17515968778823099,"ARHGDIA;SKI;SYNGAP1"]
["GO:0044454","nuclear chromosome part",1.6766233621526301E-2,0.17533233344855201,"RFX3;SMARCA2;TBP;BAZ1B;PLCB1"]
["GO:0004386","helicase activity",1.69638661652089E-2,0.17667487486873301,"CHD2;SMARCA2;CHD1L;DDX53"]
["GO:0010942","positive regulation of cell death",1.7232301806940301E-2,0.17667487486873301,"ABL1;ERCC6;ESR2;ETS1;PPP3CB;MAPK8;CUL2;IKBKG;TICAM1"]
["GO:0030520","intracellular estrogen receptor signaling pathway",1.7246939601828201E-2,0.17667487486873301,"ESR2;CYP7B1"]
["GO:0035176","social behavior",1.7246939601828201E-2,0.17667487486873301,"PPP3CB;NRXN1"]
["GO:0060512","prostate gland morphogenesis",1.7246939601828201E-2,0.17667487486873301,"ESR2;CYP7B1"]
["NCI:16","NCI:AR_NONGENOMIC_PATHWAY",1.7246939601828201E-2,0.17667487486873301,"MAPK3;PLCB1"]
["NCI:35","NCI:CD40_PATHWAY",1.7246939601828201E-2,0.17667487486873301,"MAPK8;MAPK11"]
["GO:0071158","positive regulation of cell cycle arrest",1.72778574302213E-2,0.17667487486873301,"CDK2;PSMB1;PSMC2"]
["REACT:520","REACT: IRS-mediated signalling",1.72778574302213E-2,0.17667487486873301,"MAPK3;PIK3CB;PRKAB2"]
["REACT:521","REACT: IRS-related events",1.72778574302213E-2,0.17667487486873301,"MAPK3;PIK3CB;PRKAB2"]
["KEGG:04070","Phosphatidylinositol signaling system",1.72778574302213E-2,0.17667487486873301,"PLCB1;PIK3CB;SYNJ2"]
["NCI:42","NCI:CMYB_PATHWAY",1.72778574302213E-2,0.17667487486873301,"ETS1;SKI;SMARCA2"]
["GO:0008047","enzyme activator activity",1.7480306899049999E-2,0.17841523572978699,"ARHGDIA;RAP1GDS1;SYNGAP1;ARHGAP32;PLCB1;SMAP1;RALGAPA1"]
["GO:0044212","transcription regulatory region DNA binding",1.75238407087288E-2,0.17848860805164399,"ESR2;RFX3;SMARCA2;SREBF1;TBP;UHRF1"]
["GO:0072358","cardiovascular system development",1.7584289838782699E-2,0.17848860805164399,"CHRNA7;CRKL;ETS1;PPP3CB;MAPK7;SMARCA2;SOD2;BAZ1B;NRXN3;NRXN1"]
["GO:0072359","circulatory system development",1.7584289838782699E-2,0.17848860805164399,"CHRNA7;CRKL;ETS1;PPP3CB;MAPK7;SMARCA2;SOD2;BAZ1B;NRXN3;NRXN1"]
["GO:0009057","macromolecule catabolic process",1.7762606516191801E-2,0.179193166812498,"CDK2;CSNK1D;FLNA;PARK2;PSMB1;PSMC2;RNASE6;RPL19;UBE3A;CUL2;TRIP12"]
["GO:0006914","autophagy",1.7848054033565899E-2,0.179193166812498,"ABL1;PARK2;PIK3CB"]
["REACT:18","REACT: APC/C-mediated degradation of cell cycle proteins",1.7848054033565899E-2,0.179193166812498,"CDK2;PSMB1;PSMC2"]
["REACT:281","REACT: DNA Replication Pre-Initiation",1.7848054033565899E-2,0.179193166812498,"CDK2;PSMB1;PSMC2"]
["REACT:607","REACT: M/G1 Transition",1.7848054033565899E-2,0.179193166812498,"CDK2;PSMB1;PSMC2"]
["REACT:936","REACT: Regulation of mitotic cell cycle",1.7848054033565899E-2,0.179193166812498,"CDK2;PSMB1;PSMC2"]
["GO:0090068","positive regulation of cell cycle process",1.8139975417459001E-2,0.18165954524762101,"CDK2;PSMB1;PSMC2;PLCB1"]
["GO:0040011","locomotion",1.8192872984238401E-2,0.18165954524762101,"ABL1;ATOH1;ESR2;ETS1;LIMK1;PIK3CB;MAPK3;RFX3;SKI;TAOK2;NRXN3;NRXN1;ZEB2;PLCB1"]
["GO:0006360","transcription from RNA polymerase I promoter",1.8356414640893E-2,0.18165954524762101,"MAPK3;KAT2B"]
["GO:0045429","positive regulation of nitric oxide biosynthetic process",1.8356414640893E-2,0.18165954524762101,"SOD2;TICAM1"]
["GO:0045921","positive regulation of exocytosis",1.8356414640893E-2,0.18165954524762101,"RAB5A;PLCB1"]
["GO:0046686","response to cadmium ion",1.8356414640893E-2,0.18165954524762101,"MAPK8;SOD2"]
["NCI:27","NCI:AVB3_OPN_PATHWAY",1.8356414640893E-2,0.18165954524762101,"MAPK3;MAPK8"]
["NCI:141","NCI:NEPHRIN_NEPH1_PATHWAY",1.8356414640893E-2,0.18165954524762101,"PIK3CB;MAPK8"]
["GO:0031145","anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process",1.84286648494844E-2,0.18204888204883499,"CDK2;PSMB1;PSMC2"]
["REACT:427","REACT: G2/M Transition",1.9019701815431899E-2,0.18755256763452599,"CEP70;CSNK1D;TUBGCP5"]
["GO:0007169","transmembrane receptor protein tyrosine kinase signaling pathway",1.9385687220796199E-2,0.18987314394518501,"ARHGDIA;PIK3CB;PRKAB2;MAPK3;MAPK7;MAPK8;MAPK11;MAPK12;PLCB1"]
["GO:0060324","face development",1.9495290267690701E-2,0.18987314394518501,"SKI;NRXN1"]
["GO:0004003","ATP-dependent DNA helicase activity",1.9495290267690701E-2,0.18987314394518501,"CHD2;CHD1L"]
["NCI:7","NCI:ALPHASYNUCLEIN_PATHWAY",1.9495290267690701E-2,0.18987314394518501,"PARK2;MAPK3"]
["NCI:65","NCI:ERBB1_RECEPTOR_PROXIMAL_PATHWAY",1.9495290267690701E-2,0.18987314394518501,"PIK3CB;MAPK3"]
["NCI:101","NCI:IL12_STAT4PATHWAY",1.9495290267690701E-2,0.18987314394518501,"PPP3CB;MAPK8"]
["NCI:223","NCI:WNT_NONCANONICAL_PATHWAY",1.9495290267690701E-2,0.18987314394518501,"FLNA;MAPK8"]
["GO:0021543","pallium development",1.96211751045345E-2,0.19009516756267,"ATOH1;ZEB2;PLCB1"]
["GO:0031575","mitotic cell cycle G1/S transition checkpoint",1.96211751045345E-2,0.19009516756267,"CDK2;PSMB1;PSMC2"]
["GO:0034101","erythrocyte homeostasis",1.96211751045345E-2,0.19009516756267,"ETS1;KLF13;SMAP1"]
["GO:0007167","enzyme linked receptor protein signaling pathway",1.9780822228026601E-2,0.19101759361219101,"ARHGDIA;PIK3CB;PRKAB2;MAPK3;MAPK7;MAPK8;MAPK11;PTPRD;MAPK12;SKI;PLCB1"]
["GO:0006650","glycerophospholipid metabolic process",1.9785444891501299E-2,0.19101759361219101,"PCYT1A;PIK3CB;SYNJ2;PLCB1"]
["GO:0000975","regulatory region DNA binding",1.9894928474128701E-2,0.191081337394367,"ESR2;RFX3;SMARCA2;SREBF1;TBP;UHRF1"]
["GO:0001067","regulatory region nucleic acid binding",1.9894928474128701E-2,0.191081337394367,"ESR2;RFX3;SMARCA2;SREBF1;TBP;UHRF1"]
["GO:0031252","cell leading edge",1.9895670704836499E-2,0.191081337394367,"RAB5A;RAC3;SYNJ2;CYFIP1;SNX9"]
["REACT:551","REACT: Insulin receptor signalling cascade",2.02330931555562E-2,0.19364960438847201,"MAPK3;PIK3CB;PRKAB2"]
["REACT:935","REACT: Regulation of mRNA Stability by Proteins that Bind AU-rich Elements",2.02330931555562E-2,0.19364960438847201,"MAPK11;PSMB1;PSMC2"]
["GO:0004693","cyclin-dependent protein kinase activity",2.06631285960404E-2,0.195733608550164,"CDK2;CDK4"]
["REACT:1087","REACT: Synthesis of PIPs at the plasma membrane",2.06631285960404E-2,0.195733608550164,"PIK3CB;SYNJ2"]
["NCI:61","NCI:EPOPATHWAY",2.06631285960404E-2,0.195733608550164,"CRKL;MAPK8"]
["NCI:113","NCI:IL8CXCR2_PATHWAY",2.06631285960404E-2,0.195733608550164,"RAB5A;PLCB1"]
["NCI:133","NCI:MAPKTRKPATHWAY",2.06631285960404E-2,0.195733608550164,"MAPK3;MAPK7"]
["NCI:198","NCI:SYNDECAN_2_PATHWAY",2.06631285960404E-2,0.195733608550164,"MAPK3;MAPK8"]
["KEGG:04210","Apoptosis",2.0855462702504501E-2,0.197217811402145,"PPP3CB;IKBKG;PIK3CB"]
["GO:0030900","forebrain development",2.12479475166042E-2,0.20058642604412,"ATOH1;ETS1;SKI;ZEB2;PLCB1"]
["GO:0071216","cellular response to biotic stimulus",2.1488288803878802E-2,0.20250973366790001,"ABCA1;MAPK3;TICAM1"]
["GO:0051247","positive regulation of protein metabolic process",2.1684883452755599E-2,0.20358035857965301,"CSNK1D;MAPK3;MAPK7;PSMB1;PSMC2;TNK2;UHRF1;TICAM1"]
["GO:0010171","body morphogenesis",2.18594962032382E-2,0.20358035857965301,"SKI;NRXN1"]
["GO:0031663","lipopolysaccharide-mediated signaling pathway",2.18594962032382E-2,0.20358035857965301,"MAPK3;TICAM1"]
["GO:0043331","response to dsRNA",2.18594962032382E-2,0.20358035857965301,"MAPK3;TICAM1"]
["GO:0050771","negative regulation of axonogenesis",2.18594962032382E-2,0.20358035857965301,"ARHGDIA;SYNGAP1"]
["GO:0060078","regulation of postsynaptic membrane potential",2.18594962032382E-2,0.20358035857965301,"GRID2;NRXN1"]
["GO:0070936","protein K48-linked ubiquitination",2.18594962032382E-2,0.20358035857965301,"PARK2;UBE3A"]
["GO:0071779","G1/S transition checkpoint",2.2131574871565699E-2,0.20514436642011,"CDK2;PSMB1;PSMC2"]
["GO:0022603","regulation of anatomical structure morphogenesis",2.2137002186411899E-2,0.20514436642011,"ARHGDIA;CHRNA7;ETS1;LIMK1;MAPK7;SYNGAP1;TAOK2;CYFIP1"]
["REACT:86","REACT: Adaptive Immune System",2.2138681625597501E-2,0.20514436642011,"CUL2;IKBKG;PARK2;PIK3CB;PSMB1;PSMC2;TRIP12;UBE2W;UBE3A"]
["GO:0031397","negative regulation of protein ubiquitination",2.27853226993847E-2,0.210783286242469,"LIMK1;PSMB1;PSMC2"]
["GO:0045087","innate immune response",2.3061276677085601E-2,0.212127058720955,"CAMK2G;MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;IL1RL1;TICAM1"]
["GO:0010332","response to gamma radiation",2.3083964090747498E-2,0.212127058720955,"ERCC6;SOD2"]
["NCI:67","NCI:ERBB4_PATHWAY",2.3083964090747498E-2,0.212127058720955,"PIK3CB;MAPK3"]
["NCI:102","NCI:IL1PATHWAY",2.3083964090747498E-2,0.212127058720955,"MAPK8;IKBKG"]
["REACT:302","REACT: Developmental Biology",2.3256850692720099E-2,0.21312462207524899,"ABL1;CDK4;LIMK1;MAPK11;MAPK12;MAPK3;SREBF1"]
["GO:0007010","cytoskeleton organization",2.3269571896863801E-2,0.21312462207524899,"ABL1;CDK2;CSNK1D;FLNA;LIMK1;PARK2;MAPK3;RAC3;TAOK2;TUBGCP5"]
["GO:0050804","regulation of synaptic transmission",2.33460703958897E-2,0.213471837074482,"PARK2;PPP3CB;SYNGAP1;NRXN1"]
["GO:0022602","ovulation cycle process",2.3449532491286899E-2,0.21406404907887699,"ESR2;ETS1;UBE3A"]
["GO:0002684","positive regulation of immune system process",2.4012579929564098E-2,0.21848288185912601,"PIK3CB;MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;IL1RL1;TICAM1"]
["GO:0005768","endosome",2.4012579929564098E-2,0.21848288185912601,"CDK2;MAPK3;RAB5A;SH3GL3;ARHGAP32;TNK2;STEAP3;TICAM1"]
["GO:0070997","neuron death",2.4293204240847702E-2,0.21962046899395399,"GRID2;MAX;PARK2;SOD2"]
["GO:0006476","protein deacetylation",2.43361076452085E-2,0.21962046899395399,"MAPK8;SKI"]
["GO:0042116","macrophage activation",2.43361076452085E-2,0.21962046899395399,"IL1RL1;TICAM1"]
["GO:0042645","mitochondrial nucleoid",2.43361076452085E-2,0.21962046899395399,"DBT;SOD2"]
["NCI:139","NCI:NCADHERINPATHWAY",2.43361076452085E-2,0.21962046899395399,"CAMK2G;MAPK8"]
["GO:0009611","response to wounding",2.4451561401875599E-2,0.220302992956312,"ABL1;CDK2;ETS1;FLNA;MAX;PIK3CB;MAPK3;MAPK7;RAB5A;SOD2;IKBKG;IL1RL1;TICAM1"]
["GO:0046486","glycerolipid metabolic process",2.4506781268369901E-2,0.22044148614084999,"PCYT1A;PIK3CB;SREBF1;SYNJ2;PLCB1"]
["REACT:320","REACT: Downstream signal transduction",2.4809331000606099E-2,0.22280068034959899,"CRKL;MAPK3;PIK3CB"]
["GO:0043086","negative regulation of catalytic activity",2.5240280663311299E-2,0.22630345644965699,"ABL1;FLNA;GALR1;LIMK1;PSMB1;PSMC2;SKI;KAT2B"]
["GO:0003700","sequence-specific DNA binding transcription factor activity",2.5386042930158999E-2,0.22636578675702099,"ATOH1;BNC1;ESR2;ETS1;MAX;RFX3;SREBF1;TBP;ZEB2;UHRF1;ZSCAN2;KCNH8"]
["GO:0060284","regulation of cell development",2.54456348021245E-2,0.22636578675702099,"ARHGDIA;ATOH1;LIMK1;RFX3;SKI;SYNGAP1;PLCB1"]
["GO:0050770","regulation of axonogenesis",2.5504912425601999E-2,0.22636578675702099,"ARHGDIA;LIMK1;SYNGAP1"]
["GO:0001071","nucleic acid binding transcription factor activity",2.5568500299514099E-2,0.22636578675702099,"ATOH1;BNC1;ESR2;ETS1;MAX;RFX3;SREBF1;TBP;ZEB2;UHRF1;ZSCAN2;KCNH8"]
["GO:0035601","protein deacylation",2.5615506599764099E-2,0.22636578675702099,"MAPK8;SKI"]
["GO:0045445","myoblast differentiation",2.5615506599764099E-2,0.22636578675702099,"MAPK12;PLCB1"]
["GO:0009295","nucleoid",2.5615506599764099E-2,0.22636578675702099,"DBT;SOD2"]
["NCI:175","NCI:RAC1_REG_PATHWAY",2.5615506599764099E-2,0.22636578675702099,"ARHGDIA;RAP1GDS1"]
["NCI:183","NCI:RET_PATHWAY",2.5615506599764099E-2,0.22636578675702099,"MAPK3;MAPK8"]
["GO:0032868","response to insulin stimulus",2.5660805822613601E-2,0.226404430320094,"MAX;PIK3CB;PRKAB2;MAPK3;KAT2B"]
["GO:0002790","peptide secretion",2.6256673846161298E-2,0.23092515058340901,"ABCA1;CAMK2G;PPP3CB;RFX3"]
["GO:0030031","cell projection assembly",2.6256673846161298E-2,0.23092515058340901,"RAB5A;RAC3;RFX3;CYFIP1"]
["GO:0008630","DNA damage response, signal transduction resulting in induction of apoptosis",2.69217449957001E-2,0.23458940972947701,"ABL1;ERCC6"]
["GO:0033143","regulation of intracellular steroid hormone receptor signaling pathway",2.69217449957001E-2,0.23458940972947701,"ESR2;CYP7B1"]
["GO:0048639","positive regulation of developmental growth",2.69217449957001E-2,0.23458940972947701,"LIMK1;PLCB1"]
["NCI:149","NCI:P38ALPHABETADOWNSTREAMPATHWAY",2.69217449957001E-2,0.23458940972947701,"MAPK11;RAB5A"]
["REACT:1074","REACT: Synthesis of DNA",2.6927410241139999E-2,0.23458940972947701,"CDK2;PSMB1;PSMC2"]
["GO:0010740","positive regulation of intracellular protein kinase cascade",2.6927743163090701E-2,0.23458940972947701,"FLNA;PARK2;IKBKG;TAOK2;PLCB1;TICAM1"]
["GO:0048589","developmental growth",2.7253076269846299E-2,0.23705034264904001,"LIMK1;PPP3CB;UBE3A;CYFIP1;PLCB1"]
["GO:0007411","axon guidance",2.7608150745924001E-2,0.239761836619233,"ABL1;ATOH1;LIMK1;MAPK3;NRXN3;NRXN1"]
["GO:0009187","cyclic nucleotide metabolic process",2.7790229674818201E-2,0.240964812791684,"ABCA1;CBS;FLNA;GALR1"]
["GO:0016604","nuclear body",2.80723671095338E-2,0.242006946439352,"CDK2;MAX;SKI;PLCB1;ANKS1B"]
["GO:0001836","release of cytochrome c from mitochondria",2.8254411144397001E-2,0.242006946439352,"PARK2;SOD2"]
["GO:0051225","spindle assembly",2.8254411144397001E-2,0.242006946439352,"CSNK1D;FLNA"]
["GO:0071347","cellular response to interleukin-1",2.8254411144397001E-2,0.242006946439352,"MAPK3;PLCB1"]
["GO:0030145","manganese ion binding",2.8254411144397001E-2,0.242006946439352,"ABL1;SOD2"]
["KEGG:04960","Aldosterone-regulated sodium reabsorption",2.8254411144397001E-2,0.242006946439352,"PIK3CB;MAPK3"]
["NCI:64","NCI:ERBB1_INTERNALIZATION_PATHWAY",2.8254411144397001E-2,0.242006946439352,"PIK3CB;RAB5A"]
["GO:0009719","response to endogenous stimulus",2.8307539033779999E-2,0.242006946439352,"ABCA1;ESR2;ETS1;MAX;PIK3CB;PPP3CB;PRKAB2;MAPK3;MAPK7;KAT2B;PLCB1"]
["GO:0030518","intracellular steroid hormone receptor signaling pathway",2.83916320027367E-2,0.242006946439352,"ESR2;UBE3A;CYP7B1"]
["GO:0046488","phosphatidylinositol metabolic process",2.83916320027367E-2,0.242006946439352,"PIK3CB;SYNJ2;PLCB1"]
["REACT:318","REACT: Downstream Signaling Events Of B Cell Receptor (BCR)",2.83916320027367E-2,0.242006946439352,"IKBKG;PSMB1;PSMC2"]
["GO:0032269","negative regulation of cellular protein metabolic process",2.84878379861346E-2,0.24245341498353301,"LIMK1;PARK2;PSMB1;PSMC2;SKI"]
["GO:0031965","nuclear membrane",2.88417975680752E-2,0.24508882357387399,"ABL1;CDK4;WTAP;CEP70"]
["GO:0006887","exocytosis",2.8907205912674899E-2,0.245267888203861,"FLNA;PPP3CB;RAB5A;RIMS1;PLCB1"]
["GO:0042698","ovulation cycle",2.91393631029624E-2,0.246481585146159,"ESR2;ETS1;UBE3A"]
["GO:2000045","regulation of G1/S transition of mitotic cell cycle",2.91393631029624E-2,0.246481585146159,"CDK2;PSMB1;PSMC2"]
["GO:0048732","gland development",2.9330480707073E-2,0.24720470655510601,"CRKL;ESR2;ETS1;UBE3A;CYP7B1"]
["GO:0045184","establishment of protein localization",2.9357219741896399E-2,0.24720470655510601,"ABCA1;FLNA;MAPK3;MAPK7;RAB5A;RPL19;IL1RL1;TAOK2;NRXN1;RIMS1;SNX9;STEAP3;PARD3;SNX14"]
["GO:0010035","response to inorganic substance",2.9358910377206199E-2,0.24720470655510601,"CDK2;ERCC6;ETS1;MAPK8;SOD2;CUTA"]
["KEGG:05033","Nicotine addiction",2.96130975895918E-2,0.24896604234896899,"CACNA1B;CHRNA7"]
["GO:0045596","negative regulation of cell differentiation",2.97176540152072E-2,0.24946595145997899,"ABCA1;ARHGDIA;SKI;SOD2;SYNGAP1;KLF13"]
["GO:0032102","negative regulation of response to external stimulus",2.9897490944779899E-2,0.25021621771032099,"GRID2;MAPK7;NRXN1"]
["NCI:45","NCI:CXCR4_PATHWAY",2.9897490944779899E-2,0.25021621771032099,"LIMK1;PIK3CB;PLCB1"]
["GO:0051969","regulation of transmission of nerve impulse",3.04631462617184E-2,0.25456514368553801,"PARK2;PPP3CB;SYNGAP1;NRXN1"]
["KEGG:04916","Melanogenesis",3.0666001310746899E-2,0.25587378469238597,"CAMK2G;PLCB1;MAPK3"]
["GO:0002260","lymphocyte homeostasis",3.0997401069946098E-2,0.256703028022368,"PPP3CB;IKBKG"]
["GO:0045428","regulation of nitric oxide biosynthetic process",3.0997401069946098E-2,0.256703028022368,"SOD2;TICAM1"]
["GO:0050803","regulation of synapse structure and activity",3.0997401069946098E-2,0.256703028022368,"SYNGAP1;NRXN1"]
["GO:0030545","receptor regulator activity",3.0997401069946098E-2,0.256703028022368,"ESR2;BAZ1B"]
["NCI:77","NCI:FOXM1PATHWAY",3.0997401069946098E-2,0.256703028022368,"CDK2;CDK4"]
["GO:0010721","negative regulation of cell development",3.1444878681886501E-2,0.259631446071935,"ARHGDIA;SKI;SYNGAP1"]
["GO:0018105","peptidyl-serine phosphorylation",3.1444878681886501E-2,0.259631446071935,"MAPK7;MAPK8;MAPK12"]
["GO:0003713","transcription coactivator activity",3.1505787776406301E-2,0.25974667359028297,"ESR2;MAX;SMARCA2;UBE3A;KAT2B"]
["GO:0032270","positive regulation of cellular protein metabolic process",3.1856072426190297E-2,0.26224373907988802,"CSNK1D;MAPK3;PSMB1;PSMC2;TNK2;UHRF1;TICAM1"]
["GO:0016049","cell growth",3.1930909794152397E-2,0.26246923177006098,"ESR2;LIMK1;PPP3CB;SMARCA2;TAOK2;CYFIP1"]
["GO:0032231","regulation of actin filament bundle assembly",3.2406922481919301E-2,0.26286670846037802,"LIMK1;PARK2"]
["GO:0032642","regulation of chemokine production",3.2406922481919301E-2,0.26286670846037802,"IL1RL1;TICAM1"]
["GO:0050885","neuromuscular process controlling balance",3.2406922481919301E-2,0.26286670846037802,"RAC3;NRXN1"]
["GO:0003678","DNA helicase activity",3.2406922481919301E-2,0.26286670846037802,"CHD2;CHD1L"]
["GO:0005080","protein kinase C binding",3.2406922481919301E-2,0.26286670846037802,"FLNA;PARD3"]
["GO:0008188","neuropeptide receptor activity",3.2406922481919301E-2,0.26286670846037802,"GALR1;NTSR2"]
["REACT:569","REACT: Interleukin-2 signaling",3.2406922481919301E-2,0.26286670846037802,"MAPK3;PIK3CB"]
["KEGG:05219","Bladder cancer",3.2406922481919301E-2,0.26286670846037802,"CDK4;MAPK3"]
["NCI:210","NCI:THROMBIN_PAR1_PATHWAY",3.2406922481919301E-2,0.26286670846037802,"ARHGDIA;PLCB1"]
["GO:0022604","regulation of cell morphogenesis",3.28584405365724E-2,0.26613893564907598,"ARHGDIA;LIMK1;SYNGAP1;TAOK2;CYFIP1"]
["GO:0051056","regulation of small GTPase mediated signal transduction",3.3076952595469201E-2,0.267517107833532,"ARHGDIA;RAC3;SYNGAP1;ARHGAP32;SMAP1;RALGAPA1"]
["GO:0015833","peptide transport",3.3283287890293597E-2,0.268792917677525,"ABCA1;CAMK2G;PPP3CB;RFX3"]
["GO:0001776","leukocyte homeostasis",3.38412668429438E-2,0.27111656091893599,"PPP3CB;IKBKG"]
["GO:0006801","superoxide metabolic process",3.38412668429438E-2,0.27111656091893599,"CBS;SOD2"]
["GO:0032602","chemokine production",3.38412668429438E-2,0.27111656091893599,"IL1RL1;TICAM1"]
["GO:0032947","protein complex scaffold",3.38412668429438E-2,0.27111656091893599,"BAZ1B;SHANK2"]
["GO:0030100","regulation of endocytosis",3.3843538621996898E-2,0.27111656091893599,"ABL1;PIK3CB;TNK2"]
["REACT:1162","REACT: Transcription",3.3865065725774503E-2,0.27111656091893599,"ERCC6;KAT2B;MAPK3;TBP"]
["GO:0010605","negative regulation of macromolecule metabolic process",3.47673758657846E-2,0.27793803943572398,"CDK2;ESR2;FLNA;LIMK1;MAX;PARK2;PSMB1;PSMC2;RFX3;SKI;SMARCA2;PLCB1;EHMT1"]
["GO:0031532","actin cytoskeleton reorganization",3.53000432549005E-2,0.27977054338984197,"ABL1;FLNA"]
["GO:0050772","positive regulation of axonogenesis",3.53000432549005E-2,0.27977054338984197,"ARHGDIA;LIMK1"]
["GO:0042734","presynaptic membrane",3.53000432549005E-2,0.27977054338984197,"NRXN1;RIMS1"]
["KEGG:03050","Proteasome",3.53000432549005E-2,0.27977054338984197,"PSMC2;PSMB1"]
["KEGG:04962","Vasopressin-regulated water reabsorption",3.53000432549005E-2,0.27977054338984197,"ARHGDIA;RAB5A"]
["NCI:40","NCI:CERAMIDE_PATHWAY",3.53000432549005E-2,0.27977054338984197,"MAPK3;MAPK8"]
["GO:0072593","reactive oxygen species metabolic process",3.5494139381609502E-2,0.28026105833388298,"CBS;PARK2;SOD2"]
["GO:0033267","axon part",3.5494139381609502E-2,0.28026105833388298,"SYNJ2;DLGAP2;NRXN1"]
["GO:0071844","cellular component assembly at cellular level",3.5513919358649997E-2,0.28026105833388298,"CSNK1D;FLNA;LIMK1;PARK2;RAB5A;RAC3;RFX3;TAOK2;NRXN1;CYFIP1;SNX9;PARD3"]
["GO:0008203","cholesterol metabolic process",3.6334823024823298E-2,0.28592352912279201,"ABCA1;SREBF1;CYP7B1"]
["KEGG:05146","Amoebiasis",3.6334823024823298E-2,0.28592352912279201,"RAB5A;PIK3CB;PLCB1"]
["GO:0050777","negative regulation of immune response",3.67828648678915E-2,0.28821927542376202,"PPP3CB;IL1RL1"]
["GO:0060322","head development",3.67828648678915E-2,0.28821927542376202,"SKI;NRXN1"]
["REACT:570","REACT: Interleukin-3, 5 and GM-CSF signaling",3.67828648678915E-2,0.28821927542376202,"CRKL;PIK3CB"]
["KEGG:04080","Neuroactive ligand-receptor interaction",3.7132476229208997E-2,0.29014310534520299,"GRID2;PARD3;GALR1;NTSR2;CHRNA7"]
["GO:0000302","response to reactive oxygen species",3.7185730601906899E-2,0.29014310534520299,"ERCC6;ETS1;SOD2"]
["REACT:1029","REACT: Signaling by Insulin receptor",3.7185730601906899E-2,0.29014310534520299,"MAPK3;PIK3CB;PRKAB2"]
["GO:0031644","regulation of neurological system process",3.7480447772369203E-2,0.29162002401792803,"PARK2;PPP3CB;SYNGAP1;NRXN1"]
["GO:0032496","response to lipopolysaccharide",3.7480447772369203E-2,0.29162002401792803,"ABCA1;MAPK3;SOD2;TICAM1"]
["GO:0071375","cellular response to peptide hormone stimulus",3.7627532038635801E-2,0.292353240502434,"MAX;PIK3CB;PRKAB2;MAPK3;KAT2B"]
["GO:0008026","ATP-dependent helicase activity",3.8046837031826201E-2,0.29478305666675397,"CHD2;CHD1L;DDX53"]
["GO:0070035","purine NTP-dependent helicase activity",3.8046837031826201E-2,0.29478305666675397,"CHD2;CHD1L;DDX53"]
["GO:0005635","nuclear envelope",3.8126644294443998E-2,0.29498824648512501,"ABL1;CDK4;SREBF1;WTAP;CEP70"]
["GO:0015030","Cajal body",3.8289348844309103E-2,0.29542075007910501,"CDK2;ANKS1B"]
["GO:0017048","Rho GTPase binding",3.8289348844309103E-2,0.29542075007910501,"FLNA;CYFIP1"]
["GO:0030036","actin cytoskeleton organization",3.8351994685608903E-2,0.29549197019608398,"ABL1;FLNA;LIMK1;PARK2;RAC3;TAOK2"]
["GO:0001944","vasculature development",3.8898525505988303E-2,0.29902085901046999,"CHRNA7;CRKL;ETS1;MAPK7;SMARCA2;NRXN3;NRXN1"]
["GO:0006352","transcription initiation, DNA-dependent",3.8918116140191403E-2,0.29902085901046999,"MAPK3;TBP;KAT2B"]
["GO:0005083","small GTPase regulator activity",3.9137061628952398E-2,0.300286026257094,"ARHGDIA;SYNGAP1;RIMS1;SMAP1;RALGAPA1"]
["GO:0031324","negative regulation of cellular metabolic process",3.9766749368758202E-2,0.30299773246206602,"ESR2;FLNA;GALR1;LIMK1;PARK2;PSMB1;PSMC2;RFX3;SKI;SMARCA2;KAT2B;PLCB1;EHMT1"]
["GO:0017016","Ras GTPase binding",3.9799540680956397E-2,0.30299773246206602,"FLNA;RIMS1;CYFIP1"]
["GO:0000080","G1 phase of mitotic cell cycle",3.9819116323196402E-2,0.30299773246206602,"CDK2;CDK4"]
["GO:0030173","integral to Golgi membrane",3.9819116323196402E-2,0.30299773246206602,"LARGE;RER1"]
["GO:0004521","endoribonuclease activity",3.9819116323196402E-2,0.30299773246206602,"RNASE1;RNASE6"]
["GO:0004722","protein serine/threonine phosphatase activity",3.9819116323196402E-2,0.30299773246206602,"CAMK2G;PPP3CB"]
["GO:0031401","positive regulation of protein modification process",4.00774603119992E-2,0.30451226155605898,"CSNK1D;MAPK3;PSMB1;PSMC2;TNK2;TICAM1"]
["GO:0048870","cell motility",4.0183288310904397E-2,0.30451226155605898,"ABL1;ATOH1;ESR2;ETS1;PIK3CB;RFX3;SKI;TAOK2;ZEB2;PLCB1"]
["GO:0051674","localization of cell",4.0183288310904397E-2,0.30451226155605898,"ABL1;ATOH1;ESR2;ETS1;PIK3CB;RFX3;SKI;TAOK2;ZEB2;PLCB1"]
["GO:0018193","peptidyl-amino acid modification",4.0362524914978298E-2,0.305452103734145,"ABL1;MAPK3;MAPK7;MAPK8;MAPK12;KAT2B;TNK2;EHMT1"]
["GO:0034097","response to cytokine stimulus",4.0420748869349203E-2,0.30547483981590201,"CAMK2G;ETS1;PPP3CB;MAPK3;MAPK7;IL1RL1;PLCB1"]
["GO:0018209","peptidyl-serine modification",4.0691082357844001E-2,0.30667992861525001,"MAPK7;MAPK8;MAPK12"]
["GO:0045637","regulation of myeloid cell differentiation",4.0691082357844001E-2,0.30667992861525001,"ETS1;KLF13;SMAP1"]
["REACT:268","REACT: Cytokine Signaling in Immune system",4.1206821047782699E-2,0.30951964802818899,"CAMK2G;CRKL;IKBKG;MAPK3;PIK3CB"]
["GO:0051705","behavioral interaction between organisms",4.1371792384899998E-2,0.30951964802818899,"PPP3CB;NRXN1"]
["GO:0000792","heterochromatin",4.1371792384899998E-2,0.30951964802818899,"BAZ1B;UHRF1"]
["REACT:319","REACT: Downstream TCR signaling",4.1371792384899998E-2,0.30951964802818899,"IKBKG;PIK3CB"]
["NCI:3","NCI:AJDISS_2PATHWAY",4.1371792384899998E-2,0.30951964802818899,"ABL1;RAB5A"]
["GO:0043434","response to peptide hormone stimulus",4.1403568246720902E-2,0.30951964802818899,"MAX;PIK3CB;PRKAB2;MAPK3;KAT2B;PLCB1"]
["GO:0016585","chromatin remodeling complex",4.1592711845497399E-2,0.31051401070079798,"SMARCA2;KAT2B;BAZ1B"]
["GO:0034613","cellular protein localization",4.2247394035702698E-2,0.314976528039768,"FLNA;MAPK3;MAPK7;RPL19;SYNGAP1;TAOK2;NRXN1;RIMS1;SNX9;PARD3"]
["GO:0009612","response to mechanical stimulus",4.2504398810363199E-2,0.31561655599856198,"ETS1;MAPK3;MAPK8"]
["GO:0016125","sterol metabolic process",4.2504398810363199E-2,0.31561655599856198,"ABCA1;SREBF1;CYP7B1"]
["GO:0030330","DNA damage response, signal transduction by p53 class mediator",4.2504398810363199E-2,0.31561655599856198,"CDK2;PSMB1;PSMC2"]
["GO:0046330","positive regulation of JNK cascade",4.2947006016010897E-2,0.31762411401146101,"TAOK2;PLCB1"]
["REACT:259","REACT: Cross-presentation of soluble exogenous antigens (endosomes)",4.2947006016010897E-2,0.31762411401146101,"PSMB1;PSMC2"]
["REACT:927","REACT: Regulation of activated PAK-2p34 by proteasome mediated degradation",4.2947006016010897E-2,0.31762411401146101,"PSMB1;PSMC2"]
["GO:0071310","cellular response to organic substance",4.3257238897249202E-2,0.31926547410834599,"CAMK2G;ESR2;MAX;PIK3CB;PPP3CB;PRKAB2;MAPK3;MAPK7;SOD2;KAT2B;IL1RL1;PLCB1"]
["REACT:620","REACT: Metabolism of amino acids and derivatives",4.3305565164171098E-2,0.31926547410834599,"CBS;DBT;PSMB1;PSMC2"]
["GO:0042623","ATPase activity, coupled",4.3342077197282697E-2,0.31926547410834599,"CHD2;ERCC6;SMARCA2;CHD1L;DDX53"]
["KEGG:04670","Leukocyte transendothelial migration",4.3426111931307097E-2,0.31927774967595801,"PIK3CB;MAPK11;MAPK12"]
["GO:0070727","cellular macromolecule localization",4.3459173084959599E-2,0.31927774967595801,"FLNA;MAPK3;MAPK7;RPL19;SYNGAP1;TAOK2;NRXN1;RIMS1;SNX9;PARD3"]
["GO:0051960","regulation of nervous system development",4.3675114664184098E-2,0.32043863968470399,"ARHGDIA;ATOH1;LIMK1;SKI;SYNGAP1;NRXN1"]
["GO:0051047","positive regulation of secretion",4.3982619746271198E-2,0.32226735422036001,"PPP3CB;RAB5A;IL1RL1;PLCB1"]
["GO:0007389","pattern specification process",4.4138670625579399E-2,0.32253869881235803,"CRKL;MAPK8;RFX3;SKI;SYNGAP1;ZEB2"]
["GO:0060560","developmental growth involved in morphogenesis",4.4357818919965902E-2,0.32253869881235803,"LIMK1;PPP3CB;CYFIP1"]
["REACT:209","REACT: Cell Cycle Checkpoints",4.4357818919965902E-2,0.32253869881235803,"CDK2;PSMB1;PSMC2"]
["GO:0006809","nitric oxide biosynthetic process",4.4544390074591697E-2,0.32253869881235803,"SOD2;TICAM1"]
["GO:0008637","apoptotic mitochondrial changes",4.4544390074591697E-2,0.32253869881235803,"PARK2;SOD2"]
["GO:0031228","intrinsic to Golgi membrane",4.4544390074591697E-2,0.32253869881235803,"LARGE;RER1"]
["REACT:752","REACT: PI Metabolism",4.4544390074591697E-2,0.32253869881235803,"PIK3CB;SYNJ2"]
["REACT:937","REACT: Regulation of ornithine decarboxylase (ODC)",4.4544390074591697E-2,0.32253869881235803,"PSMB1;PSMC2"]
["NCI:34","NCI:CASPASE_PATHWAY",4.4544390074591697E-2,0.32253869881235803,"LIMK1;SREBF1"]
["GO:0031398","positive regulation of protein ubiquitination",4.5299486540838499E-2,0.32754795070649401,"PSMB1;PSMC2;TICAM1"]
["GO:0002237","response to molecule of bacterial origin",4.5354615011058301E-2,0.32754795070649401,"ABCA1;MAPK3;SOD2;TICAM1"]
["GO:0010008","endosome membrane",4.6103663296906697E-2,0.33208963784975898,"RAB5A;SH3GL3;ARHGAP32;STEAP3;TICAM1"]
["GO:0005231","excitatory extracellular ligand-gated ion channel activity",4.6163581255687702E-2,0.33208963784975898,"CHRNA7;GRID2"]
["REACT:136","REACT: Autodegradation of the E3 ubiquitin ligase COP1",4.6163581255687702E-2,0.33208963784975898,"PSMB1;PSMC2"]
["GO:0032869","cellular response to insulin stimulus",4.6750445797366397E-2,0.33587463136497497,"PIK3CB;PRKAB2;MAPK3;KAT2B"]
["REACT:623","REACT: Metabolism of lipids and lipoproteins",4.6898730791823898E-2,0.33650295556468202,"ABCA1;CYP7B1;PCYT1A;PIK3CB;PRKAB2;SREBF1;SYNJ2"]
["GO:0072331","signal transduction by p53 class mediator",4.7212566120267002E-2,0.33774322523114902,"CDK2;PSMB1;PSMC2"]
["KEGG:04144","Endocytosis",4.7457293275277E-2,0.33774322523114902,"PARD3;RAB5A;SH3GL3;SMAP1"]
["GO:0032870","cellular response to hormone stimulus",4.7470376379663101E-2,0.33774322523114902,"ESR2;MAX;PIK3CB;PRKAB2;MAPK3;KAT2B"]
["GO:0043507","positive regulation of JUN kinase activity",4.7804220057120303E-2,0.33774322523114902,"ERCC6;ZEB2"]
["GO:0048678","response to axon injury",4.7804220057120303E-2,0.33774322523114902,"MAX;SOD2"]
["GO:0071260","cellular response to mechanical stimulus",4.7804220057120303E-2,0.33774322523114902,"MAPK3;MAPK8"]
["REACT:1064","REACT: Stabilization of p53",4.7804220057120303E-2,0.33774322523114902,"PSMB1;PSMC2"]
["REACT:1207","REACT: Ubiquitin Mediated Degradation of Phosphorylated Cdc25A",4.7804220057120303E-2,0.33774322523114902,"PSMB1;PSMC2"]
["REACT:1240","REACT: Vpu mediated degradation of CD4",4.7804220057120303E-2,0.33774322523114902,"PSMB1;PSMC2"]
["REACT:1274","REACT: p53-Independent DNA Damage Response",4.7804220057120303E-2,0.33774322523114902,"PSMB1;PSMC2"]
["REACT:1275","REACT: p53-Independent G1/S DNA damage checkpoint",4.7804220057120303E-2,0.33774322523114902,"PSMB1;PSMC2"]
["KEGG:05213","Endometrial cancer",4.7804220057120303E-2,0.33774322523114902,"PIK3CB;MAPK3"]
["GO:0051046","regulation of secretion",4.7958782571743498E-2,0.33840304233021101,"PARK2;PPP3CB;RAB5A;RFX3;IL1RL1;PLCB1"]
["GO:0015031","protein transport",4.8201065668971997E-2,0.33967935704554603,"ABCA1;FLNA;MAPK3;MAPK7;RAB5A;RPL19;IL1RL1;TAOK2;RIMS1;SNX9;STEAP3;PARD3;SNX14"]
["GO:0060548","negative regulation of cell death",4.8444660876758E-2,0.34096165899519698,"ARHGDIA;ETS1;PARK2;MAPK7;MAPK8;SOD2;SYNGAP1;KCNH8"]
["GO:0035270","endocrine system development",4.9165066590079999E-2,0.34471628438063701,"CRKL;ETS1;RFX3"]
["REACT:1037","REACT: Signaling by PDGF",4.9165066590079999E-2,0.34471628438063701,"CRKL;MAPK3;PIK3CB"]
["KEGG:04726","Serotonergic synapse",4.9165066590079999E-2,0.34471628438063701,"PLCB1;CACNA1B;MAPK3"]
["GO:0001541","ovarian follicle development",4.9465950745559997E-2,0.34638688547397201,"ESR2;UBE3A"]
["GO:0044440","endosomal part",4.9553801036557703E-2,0.34656337210396598,"RAB5A;SH3GL3;ARHGAP32;STEAP3;TICAM1"]
["GO:0009123","nucleoside monophosphate metabolic process",5.03441514275784E-2,0.35120283190083701,"ABCA1;CBS;FLNA;GALR1"]
["GO:0043161","proteasomal ubiquitin-dependent protein catabolic process",5.03441514275784E-2,0.35120283190083701,"CDK2;CSNK1D;PSMB1;PSMC2"]
["GO:0061061","muscle structure development",5.0447720942929403E-2,0.35148210611622899,"ABL1;MAPK11;MAPK12;SKI;SMARCA2;PLCB1"]
["GO:0030522","intracellular receptor mediated signaling pathway",5.1080712196094599E-2,0.35198856822862801,"ESR2;UBE3A;IKBKG;CYP7B1"]
["REACT:453","REACT: Gastrin-CREB signalling pathway via PKC and MAPK",5.1080712196094599E-2,0.35198856822862801,"MAPK3;MAPK7;NTSR2;PLCB1"]
["GO:0032874","positive regulation of stress-activated MAPK cascade",5.1148421322877398E-2,0.35198856822862801,"TAOK2;PLCB1"]
["REACT:298","REACT: Destabilization of mRNA by AUF1 (hnRNP D0)",5.1148421322877398E-2,0.35198856822862801,"PSMB1;PSMC2"]
["REACT:614","REACT: Meiotic Recombination",5.1148421322877398E-2,0.35198856822862801,"CDK2;CDK4"]
["REACT:979","REACT: SCF-beta-TrCP mediated degradation of Emi1",5.1148421322877398E-2,0.35198856822862801,"PSMB1;PSMC2"]
["REACT:1222","REACT: Vif-mediated degradation of APOBEC3G",5.1148421322877398E-2,0.35198856822862801,"PSMB1;PSMC2"]
["REACT:970","REACT: Rho GTPase cycle",5.1156689959475199E-2,0.35198856822862801,"ARHGAP32;ARHGDIA;RAC3"]
["REACT:1038","REACT: Signaling by Rho GTPases",5.1156689959475199E-2,0.35198856822862801,"ARHGAP32;ARHGDIA;RAC3"]
["KEGG:04110","Cell cycle",5.1156689959475199E-2,0.35198856822862801,"CDK2;CDK4;ABL1"]
["REACT:376","REACT: Factors involved in megakaryocyte development and platelet production",5.2167075953141101E-2,0.358494738102828,"ABL1;CDK2;RAB5A"]
["GO:0040007","growth",5.2648638502931298E-2,0.36135517146180601,"ESR2;LIMK1;PPP3CB;SMARCA2;UBE3A;TAOK2;CYFIP1;PLCB1;BRMS1L"]
["GO:0045639","positive regulation of myeloid cell differentiation",5.2851283492768797E-2,0.36184814391336301,"ETS1;SMAP1"]
["GO:0070304","positive regulation of stress-activated protein kinase signaling cascade",5.2851283492768797E-2,0.36184814391336301,"TAOK2;PLCB1"]
["GO:0016197","endosome transport",5.3187124924910102E-2,0.36369737340494801,"ABCA1;FLNA;MAPK3"]
["GO:0007186","G-protein coupled receptor signaling pathway",5.3686984289224603E-2,0.36666221862714898,"ABCA1;FLNA;GALR1;PIK3CB;PLCB1;NTSR2;PARD3;SNX14"]
["GO:0030817","regulation of cAMP biosynthetic process",5.4216795977376803E-2,0.36982406331300699,"ABCA1;FLNA;GALR1"]
["GO:0007194","negative regulation of adenylate cyclase activity",5.45741926276559E-2,0.37043488787262902,"FLNA;GALR1"]
["GO:0021987","cerebral cortex development",5.45741926276559E-2,0.37043488787262902,"ATOH1;PLCB1"]
["GO:0031280","negative regulation of cyclase activity",5.45741926276559E-2,0.37043488787262902,"FLNA;GALR1"]
["REACT:230","REACT: Circadian Clock",5.45741926276559E-2,0.37043488787262902,"CSNK1D;SREBF1"]
["GO:0010498","proteasomal protein catabolic process",5.5624376077515802E-2,0.37533590857357202,"CDK2;CSNK1D;PSMB1;PSMC2"]
["GO:0032844","regulation of homeostatic process",5.5624376077515802E-2,0.37533590857357202,"ETS1;PPP3CB;KLF13;SMAP1"]
["GO:0003001","generation of a signal involved in cell-cell signaling",5.5635474517412999E-2,0.37533590857357202,"CAMK2G;PARK2;PPP3CB;RFX3;RIMS1"]
["GO:0023061","signal release",5.5635474517412999E-2,0.37533590857357202,"CAMK2G;PARK2;PPP3CB;RFX3;RIMS1"]
["GO:0030659","cytoplasmic vesicle membrane",5.5635474517412999E-2,0.37533590857357202,"CAMK2G;SREBF1;TAOK2;TNK2;SNX9"]
["GO:0006171","cAMP biosynthetic process",5.6304836952176002E-2,0.37762979441788802,"ABCA1;FLNA;GALR1"]
["GO:0030814","regulation of cAMP metabolic process",5.6304836952176002E-2,0.37762979441788802,"ABCA1;FLNA;GALR1"]
["GO:0006521","regulation of cellular amino acid metabolic process",5.63168077358564E-2,0.37762979441788802,"PSMB1;PSMC2"]
["GO:0051350","negative regulation of lyase activity",5.63168077358564E-2,0.37762979441788802,"FLNA;GALR1"]
["GO:0060349","bone morphogenesis",5.63168077358564E-2,0.37762979441788802,"CBS;SKI"]
["GO:0031344","regulation of cell projection organization",5.6402309864757201E-2,0.37774525202401599,"ARHGDIA;LIMK1;RAB5A;SYNGAP1"]
["GO:0051050","positive regulation of transport",5.7286915762551398E-2,0.38320582587476998,"ABCA1;FLNA;PPP3CB;RAB5A;IL1RL1;PLCB1"]
["GO:0044106","cellular amine metabolic process",5.7808984210039403E-2,0.38570453083476702,"CBS;DBT;PARK2;PCYT1A;PSMB1;PSMC2;SOD2"]
["GO:0030029","actin filament-based process",5.7835123075907602E-2,0.38570453083476702,"ABL1;FLNA;LIMK1;PARK2;RAC3;TAOK2"]
["GO:0042826","histone deacetylase binding",5.8078791429024099E-2,0.38570453083476702,"MAPK8;KAT2B"]
["GO:0046332","SMAD binding",5.8078791429024099E-2,0.38570453083476702,"SKI;ZEB2"]
["REACT:179","REACT: CDT1 association with the CDC6:ORC:origin complex",5.8078791429024099E-2,0.38570453083476702,"PSMB1;PSMC2"]
["NCI:72","NCI:FAK_PATHWAY",5.8078791429024099E-2,0.38570453083476702,"ETS1;MAPK8"]
["GO:0007266","Rho protein signal transduction",5.8430856809788503E-2,0.38757733797571903,"ABCA1;ARHGDIA;LIMK1"]
["GO:0046983","protein dimerization activity",5.8901652807010402E-2,0.39023226745914003,"CBS;CHRNA7;FLNA;MAX;PPP3CB;SMC2;PLCB1;SNX9;RALGAPA1"]
["GO:0010243","response to organic nitrogen",5.9507998808658098E-2,0.393777810298441,"MAX;PPP3CB;PLCB1"]
["GO:0001843","neural tube closure",5.9859809889854898E-2,0.39421960513175902,"SKI;ZEB2"]
["GO:0014065","phosphatidylinositol 3-kinase cascade",5.9859809889854898E-2,0.39421960513175902,"PIK3CB;UBE3A"]
["GO:0030521","androgen receptor signaling pathway",5.9859809889854898E-2,0.39421960513175902,"ESR2;UBE3A"]
["GO:0042990","regulation of transcription factor import into nucleus",5.9859809889854898E-2,0.39421960513175902,"FLNA;MAPK7"]
["GO:0019904","protein domain specific binding",6.0764291283555497E-2,0.39970042732536099,"ABL1;PARK2;SKI;IKBKG;SYNGAP1;SYNJ2;SHANK2"]
["REACT:624","REACT: Metabolism of mRNA",6.1193149856333E-2,0.40204335511310502,"MAPK11;PSMB1;PSMC2;RPL19"]
["GO:0030815","negative regulation of cAMP metabolic process",6.16595328400594E-2,0.402241197725482,"FLNA;GALR1"]
["GO:0030818","negative regulation of cAMP biosynthetic process",6.16595328400594E-2,0.402241197725482,"FLNA;GALR1"]
["GO:0042991","transcription factor import into nucleus",6.16595328400594E-2,0.402241197725482,"FLNA;MAPK7"]
["GO:0060606","tube closure",6.16595328400594E-2,0.402241197725482,"SKI;ZEB2"]
["REACT:135","REACT: Autodegradation of Cdh1 by Cdh1:APC/C",6.16595328400594E-2,0.402241197725482,"PSMB1;PSMC2"]
["REACT:906","REACT: Regulation of Apoptosis",6.16595328400594E-2,0.402241197725482,"PSMB1;PSMC2"]
["GO:0030802","regulation of cyclic nucleotide biosynthetic process",6.2795408744443199E-2,0.40916867040548899,"ABCA1;FLNA;GALR1"]
["GO:0021761","limbic system development",6.3477633508597101E-2,0.41080197232591698,"ETS1;ZEB2"]
["GO:0030800","negative regulation of cyclic nucleotide metabolic process",6.3477633508597101E-2,0.41080197232591698,"FLNA;GALR1"]
["GO:0030803","negative regulation of cyclic nucleotide biosynthetic process",6.3477633508597101E-2,0.41080197232591698,"FLNA;GALR1"]
["GO:0031345","negative regulation of cell projection organization",6.3477633508597101E-2,0.41080197232591698,"ARHGDIA;SYNGAP1"]
["GO:0012506","vesicle membrane",6.3481048203406901E-2,0.41080197232591698,"CAMK2G;SREBF1;TAOK2;TNK2;SNX9"]
["GO:0033043","regulation of organelle organization",6.3491628043864601E-2,0.41080197232591698,"ABL1;LIMK1;PARK2;MAPK3;MAPK8;SKI"]
["GO:0071495","cellular response to endogenous stimulus",6.3811585782433206E-2,0.41158156234098697,"ESR2;MAX;PIK3CB;PRKAB2;MAPK3;MAPK7;KAT2B"]
["GO:0030808","regulation of nucleotide biosynthetic process",6.3909718375073796E-2,0.41158156234098697,"ABCA1;FLNA;GALR1"]
["REACT:711","REACT: Neurotransmitter Receptor Binding And Downstream Transmission In The  Postsynaptic Cell",6.3909718375073796E-2,0.41158156234098697,"CAMK2G;CHRNA7;PLCB1"]
["KEGG:05162","Measles",6.3909718375073796E-2,0.41158156234098697,"PIK3CB;CDK2;CDK4"]
["GO:0009306","protein secretion",6.5033202107727603E-2,0.41530560751281898,"ABCA1;IL1RL1;STEAP3"]
["GO:0018205","peptidyl-lysine modification",6.5033202107727603E-2,0.41530560751281898,"MAPK3;KAT2B;EHMT1"]
["GO:0006886","intracellular protein transport",6.5239037163335803E-2,0.41530560751281898,"FLNA;MAPK3;MAPK7;RPL19;TAOK2;RIMS1;SNX9;PARD3"]
["GO:0014020","primary neural tube formation",6.5313788600172201E-2,0.41530560751281898,"SKI;ZEB2"]
["GO:0030809","negative regulation of nucleotide biosynthetic process",6.5313788600172201E-2,0.41530560751281898,"FLNA;GALR1"]
["GO:0032640","tumor necrosis factor production",6.5313788600172201E-2,0.41530560751281898,"CHRNA7;TICAM1"]
["GO:0032680","regulation of tumor necrosis factor production",6.5313788600172201E-2,0.41530560751281898,"CHRNA7;TICAM1"]
["GO:0046209","nitric oxide metabolic process",6.5313788600172201E-2,0.41530560751281898,"SOD2;TICAM1"]
["REACT:601","REACT: Loss of Nlp from mitotic centrosomes",6.5313788600172201E-2,0.41530560751281898,"CEP70;CSNK1D"]
["REACT:602","REACT: Loss of proteins required for interphase microtubule organizationÃ‚Â from the centrosome",6.5313788600172201E-2,0.41530560751281898,"CEP70;CSNK1D"]
["NCI:206","NCI:TCR_PATHWAY",6.5313788600172201E-2,0.41530560751281898,"FLNA;IKBKG"]
["GO:0034614","cellular response to reactive oxygen species",6.7167678263987604E-2,0.424566794347006,"ETS1;SOD2"]
["GO:0048741","skeletal muscle fiber development",6.7167678263987604E-2,0.424566794347006,"SKI;PLCB1"]
["GO:0048864","stem cell development",6.7167678263987604E-2,0.424566794347006,"SKI;MSI2"]
["NCI:138","NCI:MYC_REPRESSPATHWAY",6.7167678263987604E-2,0.424566794347006,"MAX;TBP"]
["GO:0031669","cellular response to nutrient levels",6.7307497946913306E-2,0.424566794347006,"ABCA1;MAX;SREBF1"]
["GO:0045765","regulation of angiogenesis",6.7307497946913306E-2,0.424566794347006,"CHRNA7;ETS1;MAPK7"]
["GO:0046058","cAMP metabolic process",6.7307497946913306E-2,0.424566794347006,"ABCA1;FLNA;GALR1"]
["GO:0010720","positive regulation of cell development",6.8458211650097203E-2,0.43106509130831699,"ARHGDIA;LIMK1;RFX3"]
["GO:0044255","cellular lipid metabolic process",6.8706037214071203E-2,0.43106509130831699,"ABCA1;PCYT1A;PIK3CB;PRKAB2;MAPK3;SREBF1;SYNJ2;LARGE;PLCB1"]
["GO:0045980","negative regulation of nucleotide metabolic process",6.9038986062756505E-2,0.43106509130831699,"FLNA;GALR1"]
["GO:0051100","negative regulation of binding",6.9038986062756505E-2,0.43106509130831699,"MAPK3;MAPK8"]
["GO:0051101","regulation of DNA binding",6.9038986062756505E-2,0.43106509130831699,"SKI;UHRF1"]
["REACT:20","REACT: APC/C:Cdc20 mediated degradation of Securin",6.9038986062756505E-2,0.43106509130831699,"PSMB1;PSMC2"]
["REACT:331","REACT: ER-Phagosome pathway",6.9038986062756505E-2,0.43106509130831699,"PSMB1;PSMC2"]
["KEGG:04150","mTOR signaling pathway",6.9038986062756505E-2,0.43106509130831699,"MAPK3;PIK3CB"]
["KEGG:04721","Synaptic vesicle cycle",6.9038986062756505E-2,0.43106509130831699,"CACNA1B;RIMS1"]
["GO:0007093","mitotic cell cycle checkpoint",6.9617902678401802E-2,0.433700718037071,"CDK2;PSMB1;PSMC2"]
["GO:0030258","lipid modification",6.9617902678401802E-2,0.433700718037071,"PIK3CB;PRKAB2;SYNJ2"]
["GO:0017111","nucleoside-triphosphatase activity",7.0510599762346804E-2,0.43876787163701098,"ABCA1;CHD2;ERCC6;PSMC2;RAB5A;RAC3;SMARCA2;CHD1L;DDX53"]
["GO:0009267","cellular response to starvation",7.0927398941968395E-2,0.43987709747418102,"MAX;SREBF1"]
["GO:0016247","channel regulator activity",7.0927398941968395E-2,0.43987709747418102,"CHRNA7;NRXN1"]
["REACT:1103","REACT: TCR signaling",7.0927398941968395E-2,0.43987709747418102,"IKBKG;PIK3CB"]
["GO:0006644","phospholipid metabolic process",7.1401860350108398E-2,0.44232373063471397,"PCYT1A;PIK3CB;SYNJ2;PLCB1"]
["GO:0051336","regulation of hydrolase activity",7.1883489935077802E-2,0.444313532244136,"MAPK8;RAP1GDS1;SYNGAP1;PLCB1;NTSR2;UHRF1;SNX9;SMAP1;RALGAPA1"]
["GO:0001525","angiogenesis",7.1921884516198506E-2,0.444313532244136,"CHRNA7;ETS1;MAPK7;NRXN3;NRXN1"]
["GO:0045017","glycerolipid biosynthetic process",7.1964013899267099E-2,0.444313532244136,"PCYT1A;PIK3CB;SREBF1"]
["GO:0071706","tumor necrosis factor superfamily cytokine production",7.2832607199408206E-2,0.447677758919029,"CHRNA7;TICAM1"]
["GO:0004540","ribonuclease activity",7.2832607199408206E-2,0.447677758919029,"RNASE1;RNASE6"]
["GO:0051015","actin filament binding",7.2832607199408206E-2,0.447677758919029,"FLNA;CYFIP1"]
["REACT:1041","REACT: Signaling by TGF-beta Receptor Complex",7.2832607199408206E-2,0.447677758919029,"PARD3;SKI"]
["GO:0042802","identical protein binding",7.3740017471439406E-2,0.45275224933629599,"CBS;CHRNA7;FLNA;MAX;PRKAB2;SH3GL3;SOD2;PLCB1;SNX9"]
["GO:0051093","negative regulation of developmental process",7.3836509394625799E-2,0.45284209531160702,"ABCA1;ARHGDIA;SKI;SOD2;SYNGAP1;KLF13"]
["GO:0051436","negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle",7.4754304454925202E-2,0.45695117375098998,"PSMB1;PSMC2"]
["REACT:130","REACT: Assembly of the pre-replicative complex",7.4754304454925202E-2,0.45695117375098998,"PSMB1;PSMC2"]
["NCI:87","NCI:HDAC_CLASSI_PATHWAY",7.4754304454925202E-2,0.45695117375098998,"MAX;KAT2B"]
["GO:0006612","protein targeting to membrane",7.5549229690631298E-2,0.46126216831498301,"RPL19;TAOK2;PARD3"]
["GO:0031975","envelope",7.5626317183964106E-2,0.46126216831498301,"ABL1;CDK4;GRID2;SOD2;SREBF1;SYNJ2;PMPCB;WTAP;CEP70"]
["GO:0003682","chromatin binding",7.5898372840070505E-2,0.46241167241329301,"ATOH1;ERCC6;SKI;BAZ1B"]
["GO:0006955","immune response",7.6610125465421799E-2,0.46392206597728203,"CAMK2G;ETS1;PIK3CB;PPP3CB;MAPK3;MAPK7;MAPK8;MAPK11;IKBKG;IL1RL1;TICAM1"]
["GO:0016605","PML body",7.6692187620453503E-2,0.46392206597728203,"MAX;SKI"]
["REACT:290","REACT: Degradation of beta-catenin by the destruction complex",7.6692187620453503E-2,0.46392206597728203,"PSMB1;PSMC2"]
["REACT:1043","REACT: Signaling by Wnt",7.6692187620453503E-2,0.46392206597728203,"PSMB1;PSMC2"]
["NCI:219","NCI:VEGFR1_2_PATHWAY",7.6692187620453503E-2,0.46392206597728203,"MAPK3;MAPK11"]
["GO:0002683","negative regulation of immune system process",7.6761704871024405E-2,0.46392206597728203,"PPP3CB;IL1RL1;PLCB1"]
["GO:0021700","developmental maturation",7.6761704871024405E-2,0.46392206597728203,"ESR2;RFX3;NRXN1"]
["GO:0005626","insoluble fraction",7.6817175060591103E-2,0.46392206597728203,"ABCA1;GRID2;PPP3CB;MAPK3;SYNGAP1;SYNJ2;CYP7B1;SYNCRIP;CYFIP1;PLCB1"]
["GO:0003712","transcription cofactor activity",7.7706446475548904E-2,0.46840478860211698,"ESR2;MAX;SKI;SMARCA2;UBE3A;KAT2B"]
["GO:0031667","response to nutrient levels",7.7877138362423701E-2,0.46840478860211698,"ABCA1;CBS;MAX;SOD2;SREBF1"]
["GO:0030073","insulin secretion",7.7982792896339498E-2,0.46840478860211698,"CAMK2G;PPP3CB;RFX3"]
["GO:2000602","regulation of interphase of mitotic cell cycle",7.7982792896339498E-2,0.46840478860211698,"CDK2;PSMB1;PSMC2"]
["REACT:115","REACT: Apoptosis",7.7982792896339498E-2,0.46840478860211698,"MAPK8;PSMB1;PSMC2"]
["GO:0009628","response to abiotic stimulus",7.8084995063429502E-2,0.46850997038057701,"ERCC6;ETS1;PCYT1A;MAPK3;MAPK8;SOD2;SYNGAP1"]
["GO:0001764","neuron migration",7.8645956870276201E-2,0.468930874292799,"ATOH1;ESR2"]
["GO:0045995","regulation of embryonic development",7.8645956870276201E-2,0.468930874292799,"MAPK7;PLCB1"]
["REACT:21","REACT: APC/C:Cdc20 mediated degradation of mitotic proteins",7.8645956870276201E-2,0.468930874292799,"PSMB1;PSMC2"]
["REACT:22","REACT: APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1",7.8645956870276201E-2,0.468930874292799,"PSMB1;PSMC2"]
["REACT:207","REACT: Cdc20:Phospho-APC/C mediated degradation of Cyclin A",7.8645956870276201E-2,0.468930874292799,"PSMB1;PSMC2"]
["GO:0030155","regulation of cell adhesion",7.8663747531402303E-2,0.468930874292799,"ABL1;ARHGDIA;PIK3CB;MAPK7"]
["GO:0009190","cyclic nucleotide biosynthetic process",7.9212439830837006E-2,0.47169345225424097,"ABCA1;FLNA;GALR1"]
["GO:0015629","actin cytoskeleton",8.01774303785487E-2,0.47544128567486799,"ABL1;FLNA;RAC3;KAT2B;ARHGAP32"]
["GO:0001568","blood vessel development",8.0349580692372094E-2,0.47544128567486799,"CHRNA7;CRKL;ETS1;MAPK7;NRXN3;NRXN1"]
["GO:0006605","protein targeting",8.0349580692372094E-2,0.47544128567486799,"FLNA;MAPK3;MAPK7;RPL19;TAOK2;PARD3"]
["GO:0051493","regulation of cytoskeleton organization",8.0535183354408305E-2,0.47544128567486799,"ABL1;LIMK1;PARK2;MAPK3"]
["GO:0051017","actin filament bundle assembly",8.0615315611537605E-2,0.47544128567486799,"LIMK1;PARK2"]
["REACT:42","REACT: Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins",8.0615315611537605E-2,0.47544128567486799,"PSMB1;PSMC2"]
["REACT:755","REACT: PI3K Cascade",8.0615315611537605E-2,0.47544128567486799,"PIK3CB;PRKAB2"]
["KEGG:05031","Amphetamine addiction",8.0615315611537605E-2,0.47544128567486799,"CAMK2G;PPP3CB"]
["KEGG:05100","Bacterial invasion of epithelial cells",8.0615315611537605E-2,0.47544128567486799,"CRKL;PIK3CB"]
["GO:0050767","regulation of neurogenesis",8.2514068305469104E-2,0.48610961335855501,"ARHGDIA;ATOH1;LIMK1;SKI;SYNGAP1"]
["GO:0002479","antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent",8.2599970454996702E-2,0.48610961335855501,"PSMB1;PSMC2"]
["GO:0000075","cell cycle checkpoint",8.3383787597096401E-2,0.49018708711950698,"CDK2;PSMB1;PSMC2;TAOK2"]
["GO:0016462","pyrophosphatase activity",8.3470035442258797E-2,0.49018708711950698,"ABCA1;CHD2;ERCC6;PSMC2;RAB5A;RAC3;SMARCA2;CHD1L;DDX53"]
["GO:0016023","cytoplasmic membrane-bounded vesicle",8.3976151516775496E-2,0.49263634166574899,"ABCA1;CAMK2G;RAB5A;SREBF1;TAOK2;NRXN1;TNK2;TSSK2;SNX9"]
["GO:0010565","regulation of cellular ketone metabolic process",8.4215523277759302E-2,0.492637010232714,"PRKAB2;PSMB1;PSMC2"]
["GO:0004842","ubiquitin-protein ligase activity",8.4344307669313404E-2,0.492637010232714,"PARK2;UBE3A;TRIP12;UBE2W"]
["GO:0007338","single fertilization",8.4599631186022803E-2,0.492637010232714,"UBE3A;PLCB1"]
["GO:0017157","regulation of exocytosis",8.4599631186022803E-2,0.492637010232714,"RAB5A;PLCB1"]
["GO:0033238","regulation of cellular amine metabolic process",8.4599631186022803E-2,0.492637010232714,"PSMB1;PSMC2"]
["GO:0051437","positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle",8.4599631186022803E-2,0.492637010232714,"PSMB1;PSMC2"]
["KEGG:05416","Viral myocarditis",8.4599631186022803E-2,0.492637010232714,"ABL1;RAC3"]
["GO:0016818","hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides",8.4993993998459902E-2,0.49441301240744501,"ABCA1;CHD2;ERCC6;PSMC2;RAB5A;RAC3;SMARCA2;CHD1L;DDX53"]
["GO:0006928","cellular component movement",8.5252516242111498E-2,0.495395924213614,"ABL1;ARHGDIA;ATOH1;ESR2;ETS1;PIK3CB;RFX3;SKI;TAOK2;ZEB2;PLCB1"]
["GO:0032318","regulation of Ras GTPase activity",8.5487141231681094E-2,0.49571788814848999,"SYNGAP1;SMAP1;RALGAPA1"]
["REACT:1047","REACT: Signaling by the B Cell Receptor (BCR)",8.5487141231681094E-2,0.49571788814848999,"IKBKG;PSMB1;PSMC2"]
["GO:0000989","transcription factor binding transcription factor activity",8.6480588026205896E-2,0.49859386825245899,"ESR2;MAX;SKI;SMARCA2;UBE3A;KAT2B"]
["GO:0006935","chemotaxis",8.6490658565514494E-2,0.49859386825245899,"ABL1;ATOH1;LIMK1;PIK3CB;MAPK3;NRXN3;NRXN1"]
["GO:0042330","taxis",8.6490658565514494E-2,0.49859386825245899,"ABL1;ATOH1;LIMK1;PIK3CB;MAPK3;NRXN3;NRXN1"]
["GO:0016817","hydrolase activity, acting on acid anhydrides",8.6534784241266496E-2,0.49859386825245899,"ABCA1;CHD2;ERCC6;PSMC2;RAB5A;RAC3;SMARCA2;CHD1L;DDX53"]
["GO:0048747","muscle fiber development",8.6614010735830305E-2,0.49859386825245899,"SKI;PLCB1"]
["GO:0031901","early endosome membrane",8.6614010735830305E-2,0.49859386825245899,"RAB5A;SH3GL3"]
["GO:0005230","extracellular ligand-gated ion channel activity",8.6614010735830305E-2,0.49859386825245899,"CHRNA7;GRID2"]
["GO:0033273","response to vitamin",8.6766985962320603E-2,0.49895526646939498,"ABCA1;CBS;SOD2"]
["GO:0008022","protein C-terminus binding",8.8055000810582901E-2,0.50583620403338003,"ABL1;CACNA1B;ERCC6"]
["GO:0007162","negative regulation of cell adhesion",8.8642825152951799E-2,0.50710662745204704,"ARHGDIA;MAPK7"]
["GO:0045766","positive regulation of angiogenesis",8.8642825152951799E-2,0.50710662745204704,"CHRNA7;ETS1"]
["GO:0005496","steroid binding",8.8642825152951799E-2,0.50710662745204704,"ABCA1;ESR2"]
["KEGG:04971","Gastric acid secretion",8.8642825152951799E-2,0.50710662745204704,"PLCB1;CAMK2G"]
["GO:0046907","intracellular transport",8.9333333340527898E-2,0.50957777772604695,"ABCA1;FLNA;PRKAB2;MAPK3;MAPK7;RPL19;TAOK2;RER1;RIMS1;SNX9;PARD3"]
["GO:0032956","regulation of actin cytoskeleton organization",8.9351128776982203E-2,0.50957777772604695,"ABL1;LIMK1;PARK2"]
["GO:0000793","condensed chromosome",8.9351128776982203E-2,0.50957777772604695,"CDK2;BAZ1B;SMC2"]
["GO:0006508","proteolysis",8.9950529546691596E-2,0.51246789850906105,"CDK2;CSNK1D;DPP6;PARK2;PSMB1;PSMC2;UBE3A;CUL2;TRIP12;PMPCB"]
["GO:0019637","organophosphate metabolic process",9.0221526583159004E-2,0.51309877198008802,"PCYT1A;PIK3CB;SYNJ2;PLCB1"]
["GO:0043066","negative regulation of apoptotic process",9.0246765209079205E-2,0.51309877198008802,"ARHGDIA;ETS1;MAPK7;MAPK8;SOD2;SYNGAP1;KCNH8"]
["GO:0001841","neural tube formation",9.0685793574945397E-2,0.51453724108369003,"SKI;ZEB2"]
["GO:0042590","antigen processing and presentation of exogenous peptide antigen via MHC class I",9.0685793574945397E-2,0.51453724108369003,"PSMB1;PSMC2"]
["GO:0070201","regulation of establishment of protein localization",9.1219906655024496E-2,0.51703742173729095,"FLNA;MAPK7;IL1RL1;NRXN1"]
["GO:0010769","regulation of cell morphogenesis involved in differentiation",9.1967494434018193E-2,0.51967740470785295,"ARHGDIA;LIMK1;SYNGAP1"]
["GO:0051402","neuron apoptosis",9.1967494434018193E-2,0.51967740470785295,"GRID2;MAX;SOD2"]
["GO:0005516","calmodulin binding",9.1967494434018193E-2,0.51967740470785295,"CAMK2G;PPP3CB;PLCB1"]
["GO:0000226","microtubule cytoskeleton organization",9.2223619753726699E-2,0.52059292293634296,"CDK2;CSNK1D;FLNA;TUBGCP5"]
["GO:0007623","circadian rhythm",9.2742638200337596E-2,0.521394587931166,"CSNK1D;CYP7B1"]
["GO:0048167","regulation of synaptic plasticity",9.2742638200337596E-2,0.521394587931166,"PPP3CB;SYNGAP1"]
["GO:0050663","cytokine secretion",9.2742638200337596E-2,0.521394587931166,"ABCA1;IL1RL1"]
["GO:0061039","ovum-producing ovary development",9.2742638200337596E-2,0.521394587931166,"ESR2;UBE3A"]
["GO:0008286","insulin receptor signaling pathway",9.3287616527733305E-2,0.52143185561210403,"PIK3CB;PRKAB2;MAPK3"]
["GO:0030111","regulation of Wnt receptor signaling pathway",9.3287616527733305E-2,0.52143185561210403,"CSNK1D;SKI;ZEB2"]
["GO:0009725","response to hormone stimulus",9.3287915755252304E-2,0.52143185561210403,"ESR2;ETS1;MAX;PIK3CB;PRKAB2;MAPK3;KAT2B;PLCB1"]
["GO:0043069","negative regulation of programmed cell death",9.3446952799308106E-2,0.52143185561210403,"ARHGDIA;ETS1;MAPK7;MAPK8;SOD2;SYNGAP1;KCNH8"]
["GO:0031988","membrane-bounded vesicle",9.3947602774525296E-2,0.52143185561210403,"ABCA1;CAMK2G;RAB5A;SREBF1;TAOK2;NRXN1;TNK2;TSSK2;SNX9"]
["GO:0032970","regulation of actin filament-based process",9.4615620568211503E-2,0.52143185561210403,"ABL1;LIMK1;PARK2"]
["GO:0042542","response to hydrogen peroxide",9.4813084260796904E-2,0.52143185561210403,"ETS1;SOD2"]
["REACT:1167","REACT: Transcriptional Regulation of White Adipocyte Differentiation",9.4813084260796904E-2,0.52143185561210403,"CDK4;SREBF1"]
["GO:0009887","organ morphogenesis",9.5651057809599899E-2,0.52143185561210403,"ATOH1;CBS;CRKL;ESR2;MAPK3;SKI;BAZ1B;CYP7B1"]
["REACT:492","REACT: Hemostasis",9.5782406447218901E-2,0.52143185561210403,"ABL1;CDK2;FLNA;MAPK3;PIK3CB;RAB5A"]
["GO:0030072","peptide hormone secretion",9.5951448025427696E-2,0.52143185561210403,"CAMK2G;PPP3CB;RFX3"]
["GO:0031668","cellular response to extracellular stimulus",9.5951448025427696E-2,0.52143185561210403,"ABCA1;MAX;SREBF1"]
["GO:0034329","cell junction assembly",9.5951448025427696E-2,0.52143185561210403,"FLNA;TAOK2;PARD3"]
["GO:0015630","microtubule cytoskeleton",9.6132772967849001E-2,0.52143185561210403,"CDK2;CSNK1D;DBT;SYNJ2;TSSK2;STAU2;PARD3;CEP70;TUBGCP5"]
["GO:0001914","regulation of T cell mediated cytotoxicity",9.6318403009433298E-2,0.52143185561210403,"PPP3CB"]
["GO:0006688","glycosphingolipid biosynthetic process",9.6318403009433298E-2,0.52143185561210403,"LARGE"]
["GO:0032781","positive regulation of ATPase activity",9.6318403009433298E-2,0.52143185561210403,"UHRF1"]
["GO:0043401","steroid hormone mediated signaling pathway",9.6318403009433298E-2,0.52143185561210403,"ESR2"]
["GO:0045815","positive regulation of gene expression, epigenetic",9.6318403009433298E-2,0.52143185561210403,"BAZ1B"]
["GO:0050755","chemokine metabolic process",9.6318403009433298E-2,0.52143185561210403,"TICAM1"]
["GO:2000311","regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity",9.6318403009433298E-2,0.52143185561210403,"NRXN1"]
["GO:2000758","positive regulation of peptidyl-lysine acetylation",9.6318403009433298E-2,0.52143185561210403,"MAPK3"]
["GO:0016514","SWI/SNF complex",9.6318403009433298E-2,0.52143185561210403,"SMARCA2"]
["GO:0015248","sterol transporter activity",9.6318403009433298E-2,0.52143185561210403,"ABCA1"]
["GO:0052742","phosphatidylinositol kinase activity",9.6318403009433298E-2,0.52143185561210403,"PIK3CB"]
["REACT:59","REACT: Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon",9.6318403009433298E-2,0.52143185561210403,"TICAM1"]
["REACT:186","REACT: CREB phosphorylation through the activation of CaMKII",9.6318403009433298E-2,0.52143185561210403,"CAMK2G"]
["REACT:344","REACT: Endogenous sterols",9.6318403009433298E-2,0.52143185561210403,"CYP7B1"]
["REACT:482","REACT: HDL-mediated lipid transport",9.6318403009433298E-2,0.52143185561210403,"ABCA1"]
["REACT:983","REACT: SHC-mediated signalling",9.6318403009433298E-2,0.52143185561210403,"MAPK3"]
["REACT:985","REACT: SHC1 events in EGFR signaling",9.6318403009433298E-2,0.52143185561210403,"MAPK3"]
["REACT:997","REACT: Sema3A PAK dependent Axon repulsion",9.6318403009433298E-2,0.52143185561210403,"LIMK1"]
["REACT:1053","REACT: Signalling to p38 via RIT and RIN",9.6318403009433298E-2,0.52143185561210403,"MAPK3"]
["REACT:1113","REACT: TRAF6 mediated induction of TAK1 complex",9.6318403009433298E-2,0.52143185561210403,"TICAM1"]
["NCI:13","NCI:ARF6DOWNSTREAMPATHWAY",9.6318403009433298E-2,0.52143185561210403,"MAPK3"]
["NCI:69","NCI:ERB_GENOMIC_PATHWAY",9.6318403009433298E-2,0.52143185561210403,"ESR2"]
["GO:0001816","cytokine production",9.64325647069878E-2,0.52143185561210403,"ABCA1;CHRNA7;IL1RL1;PLCB1;TICAM1"]
["GO:0009991","response to extracellular stimulus",9.64325647069878E-2,0.52143185561210403,"ABCA1;CBS;MAX;SOD2;SREBF1"]
["GO:0005813","centrosome",9.64325647069878E-2,0.52143185561210403,"CDK2;CSNK1D;TSSK2;CEP70;TUBGCP5"]
["GO:0000988","protein binding transcription factor activity",9.6519562571727197E-2,0.52143185561210403,"ESR2;MAX;SKI;SMARCA2;UBE3A;KAT2B"]
["GO:0007051","spindle organization",9.6896859993538198E-2,0.52194102189313796,"CSNK1D;FLNA"]
["GO:0009855","determination of bilateral symmetry",9.6896859993538198E-2,0.52194102189313796,"MAPK8;RFX3"]
["GO:0030426","growth cone",9.6896859993538198E-2,0.52194102189313796,"RAC3;NRXN1"]
["GO:0044433","cytoplasmic vesicle part",9.7286678853345895E-2,0.52306721264647404,"CAMK2G;SREBF1;TAOK2;TNK2;SNX9"]
["GO:0004713","protein tyrosine kinase activity",9.7295040096388605E-2,0.52306721264647404,"ABL1;BAZ1B;TNK2"]
["GO:0016791","phosphatase activity",9.8356777556344893E-2,0.52758490334143204,"CAMK2G;PPP3CB;PTPRD;SYNJ2"]
["GO:0019787","small conjugating protein ligase activity",9.8356777556344893E-2,0.52758490334143204,"PARK2;UBE3A;TRIP12;UBE2W"]
["GO:0032386","regulation of intracellular transport",9.8646337715804194E-2,0.52758490334143204,"FLNA;MAPK3;MAPK7"]
["GO:0002822","regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains",9.8993696613956406E-2,0.52758490334143204,"PPP3CB;IL1RL1"]
["GO:0009799","specification of symmetry",9.8993696613956406E-2,0.52758490334143204,"MAPK8;RFX3"]
["GO:0051443","positive regulation of ubiquitin-protein ligase activity",9.8993696613956406E-2,0.52758490334143204,"PSMB1;PSMC2"]
["GO:0005802","trans-Golgi network",9.8993696613956406E-2,0.52758490334143204,"FLNA;SNX9"]
["GO:0030427","site of polarized growth",9.8993696613956406E-2,0.52758490334143204,"RAC3;NRXN1"]
["REACT:112","REACT: Antigen processing-Cross presentation",9.8993696613956406E-2,0.52758490334143204,"PSMB1;PSMC2"]
["GO:0051091","positive regulation of sequence-specific DNA binding transcription factor activity",0.100005281566605,0.53246315459717097,"ESR2;IKBKG;TICAM1"]
["GO:0002478","antigen processing and presentation of exogenous peptide antigen",0.10110332828848501,0.53442491819734295,"PSMB1;PSMC2"]
["GO:0055072","iron ion homeostasis",0.10110332828848501,0.53442491819734295,"SOD2;STEAP3"]
["REACT:736","REACT: Opioid Signalling",0.10110332828848501,0.53442491819734295,"PLCB1;PPP3CB"]
["GO:0001819","positive regulation of cytokine production",0.101371812090306,0.53442491819734295,"IL1RL1;PLCB1;TICAM1"]
["GO:0000097","sulfur amino acid biosynthetic process",0.102402460825955,0.53442491819734295,"CBS"]
["GO:0006337","nucleosome disassembly",0.102402460825955,0.53442491819734295,"BAZ1B"]
["GO:0007274","neuromuscular synaptic transmission",0.102402460825955,0.53442491819734295,"DTNA"]
["GO:0021854","hypothalamus development",0.102402460825955,0.53442491819734295,"ETS1"]
["GO:0031498","chromatin disassembly",0.102402460825955,0.53442491819734295,"BAZ1B"]
["GO:0032986","protein-DNA complex disassembly",0.102402460825955,0.53442491819734295,"BAZ1B"]
["GO:0033146","regulation of intracellular estrogen receptor signaling pathway",0.102402460825955,0.53442491819734295,"CYP7B1"]
["GO:0070207","protein homotrimerization",0.102402460825955,0.53442491819734295,"SKI"]
["GO:0090208","positive regulation of triglyceride metabolic process",0.102402460825955,0.53442491819734295,"SREBF1"]
["GO:0005892","acetylcholine-gated channel complex",0.102402460825955,0.53442491819734295,"CHRNA7"]
["GO:0004889","acetylcholine-activated cation-selective channel activity",0.102402460825955,0.53442491819734295,"CHRNA7"]
["GO:0052866","phosphatidylinositol phosphate phosphatase activity",0.102402460825955,0.53442491819734295,"SYNJ2"]
["REACT:216","REACT: Cell-extracellular matrix interactions",0.102402460825955,0.53442491819734295,"FLNA"]
["REACT:466","REACT: Glutamate Neurotransmitter Release Cycle",0.102402460825955,0.53442491819734295,"RIMS1"]
["REACT:691","REACT: NRIF signals cell death from the nucleus",0.102402460825955,0.53442491819734295,"MAPK8"]
["REACT:1062","REACT: Spry regulation of FGF signaling",0.102402460825955,0.53442491819734295,"MAPK3"]
["REACT:1105","REACT: TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)",0.102402460825955,0.53442491819734295,"PARD3"]
["GO:0005730","nucleolus",0.102744189197657,0.53522819649327402,"ABL1;CBS;CDK4;ERCC6;TAOK2;ZEB2;STAU2"]
["GO:0030816","positive regulation of cAMP metabolic process",0.103225492107682,0.53522819649327402,"ABCA1;GALR1"]
["GO:0030819","positive regulation of cAMP biosynthetic process",0.103225492107682,0.53522819649327402,"ABCA1;GALR1"]
["NCI:136","NCI:MYC_ACTIVPATHWAY",0.103225492107682,0.53522819649327402,"CDK4;MAX"]
["GO:0007017","microtubule-based process",0.1033734915334,0.53522819649327402,"CDK2;CSNK1D;FLNA;RFX3;TUBGCP5"]
["GO:0042578","phosphoric ester hydrolase activity",0.1033734915334,0.53522819649327402,"CAMK2G;PPP3CB;PTPRD;SYNJ2;PLCB1"]
["GO:0008284","positive regulation of cell proliferation",0.103427140645573,0.53522819649327402,"BNC1;CDK2;CDK4;CHRNA7;ETS1;CYP7B1;TICAM1"]
["GO:0032504","multicellular organism reproduction",0.103427140645573,0.53522819649327402,"CBS;ESR2;ETS1;TBP;UBE3A;TSSK2;ZSCAN2"]
["GO:0048609","multicellular organismal reproductive process",0.103427140645573,0.53522819649327402,"CBS;ESR2;ETS1;TBP;UBE3A;TSSK2;ZSCAN2"]
["GO:0005938","cell cortex",0.10412739377647599,0.53784569782583302,"FLNA;ARHGAP32;PARD3"]
["KEGG:05010","Alzheimer's disease",0.10412739377647599,0.53784569782583302,"PLCB1;MAPK3;PPP3CB"]
["GO:0046982","protein heterodimerization activity",0.104676787142989,0.53967566307084303,"MAX;PPP3CB;SMC2;RALGAPA1"]
["REACT:619","REACT: Metabolism of RNA",0.104676787142989,0.53967566307084303,"MAPK11;PSMB1;PSMC2;RPL19"]
["GO:0019884","antigen processing and presentation of exogenous antigen",0.10535992805953499,0.54095845638003404,"PSMB1;PSMC2"]
["GO:0060348","bone development",0.10535992805953499,0.54095845638003404,"CBS;SKI"]
["GO:0048646","anatomical structure formation involved in morphogenesis",0.105446358266792,0.54095845638003404,"CHRNA7;ETS1;MAPK7;RFX3;SKI;NRXN3;NRXN1;ZEB2"]
["GO:0071156","regulation of cell cycle arrest",0.105747963059698,0.54095845638003404,"CDK2;PSMB1;PSMC2;TAOK2"]
["GO:0048037","cofactor binding",0.105747963059698,0.54095845638003404,"CBS;DBI;DBT;STEAP3"]
["GO:0002819","regulation of adaptive immune response",0.10750637900299199,0.54095845638003404,"PPP3CB;IL1RL1"]
["GO:0042326","negative regulation of phosphorylation",0.10750637900299199,0.54095845638003404,"PARK2;KAT2B"]
["GO:0043473","pigmentation",0.10750637900299199,0.54095845638003404,"SOD2;NRXN1"]
["GO:0051351","positive regulation of ligase activity",0.10750637900299199,0.54095845638003404,"PSMB1;PSMC2"]
["GO:0044450","microtubule organizing center part",0.10750637900299199,0.54095845638003404,"TSSK2;TUBGCP5"]
["GO:0030165","PDZ domain binding",0.10750637900299199,0.54095845638003404,"PARK2;SYNJ2"]
["GO:0040008","regulation of growth",0.107942475825622,0.54095845638003404,"ESR2;LIMK1;SMARCA2;TAOK2;PLCB1;BRMS1L"]
["GO:0001913","T cell mediated cytotoxicity",0.10844593783902,0.54095845638003404,"PPP3CB"]
["GO:0007250","activation of NF-kappaB-inducing kinase activity",0.10844593783902,0.54095845638003404,"IKBKG"]
["GO:0009247","glycolipid biosynthetic process",0.10844593783902,0.54095845638003404,"LARGE"]
["GO:0015697","quaternary ammonium group transport",0.10844593783902,0.54095845638003404,"PRKAB2"]
["GO:0031057","negative regulation of histone modification",0.10844593783902,0.54095845638003404,"SKI"]
["GO:0031529","ruffle organization",0.10844593783902,0.54095845638003404,"CYFIP1"]
["GO:0032459","regulation of protein oligomerization",0.10844593783902,0.54095845638003404,"SNX9"]
["GO:0032925","regulation of activin receptor signaling pathway",0.10844593783902,0.54095845638003404,"SKI"]
["GO:0040020","regulation of meiosis",0.10844593783902,0.54095845638003404,"PLCB1"]
["GO:0043691","reverse cholesterol transport",0.10844593783902,0.54095845638003404,"ABCA1"]
["GO:0045661","regulation of myoblast differentiation",0.10844593783902,0.54095845638003404,"PLCB1"]
["GO:0060395","SMAD protein signal transduction",0.10844593783902,0.54095845638003404,"SKI"]
["GO:0016235","aggresome",0.10844593783902,0.54095845638003404,"PARK2"]
["GO:0031941","filamentous actin",0.10844593783902,0.54095845638003404,"RAC3"]
["GO:0042809","vitamin D receptor binding",0.10844593783902,0.54095845638003404,"BAZ1B"]
["REACT:24","REACT: ARMS-mediated activation",0.10844593783902,0.54095845638003404,"MAPK3"]
["REACT:45","REACT: Activation of BH3-only proteins",0.10844593783902,0.54095845638003404,"MAPK8"]
["REACT:169","REACT: Branched-chain amino acid catabolism",0.10844593783902,0.54095845638003404,"DBT"]
["REACT:300","REACT: Destabilization of mRNA by KSRP",0.10844593783902,0.54095845638003404,"MAPK11"]
["REACT:347","REACT: Energy dependent regulation of mTOR by LKB1-AMPK",0.10844593783902,0.54095845638003404,"PRKAB2"]
["REACT:890","REACT: Ras activation uopn Ca2+ infux through NMDA receptor",0.10844593783902,0.54095845638003404,"CAMK2G"]
["REACT:984","REACT: SHC-related events",0.10844593783902,0.54095845638003404,"MAPK3"]
["REACT:1210","REACT: Unblocking of NMDA receptor, glutamate binding and activation",0.10844593783902,0.54095845638003404,"CAMK2G"]
["KEGG:00120","Primary bile acid biosynthesis",0.10844593783902,0.54095845638003404,"CYP7B1"]
["GO:0048534","hemopoietic or lymphoid organ development",0.109516788102932,0.54392820730034697,"CRKL;ETS1;PPP3CB;SOD2;KLF13;SMAP1"]
["GO:0030534","adult behavior",0.10966459064171399,0.54392820730034697,"PARK2;NRXN1"]
["GO:0070925","organelle assembly",0.10966459064171399,0.54392820730034697,"CSNK1D;FLNA"]
["REACT:212","REACT: Cell junction organization",0.10966459064171399,0.54392820730034697,"FLNA;PARD3"]
["GO:0006259","DNA metabolic process",0.10986800082507001,0.54392820730034697,"ABL1;CDK2;CSNK1D;ERCC6;BAZ1B;CHD1L;SMC2;UHRF1;EHMT1"]
["GO:0003002","regionalization",0.110082822974181,0.54392820730034697,"CRKL;MAPK8;SKI;ZEB2"]
["GO:0009308","amine metabolic process",0.111103911549534,0.54392820730034697,"CBS;DBT;PARK2;PCYT1A;PSMB1;PSMC2;SOD2"]
["GO:0045121","membrane raft",0.111144903634303,0.54392820730034697,"ABCA1;MAPK3;RAB5A"]
["REACT:380","REACT: Fatty acid, triacylglycerol, and ketone body metabolism",0.111144903634303,0.54392820730034697,"ABCA1;PRKAB2;SREBF1"]
["GO:0016055","Wnt receptor signaling pathway",0.111178962559601,0.54392820730034697,"CSNK1D;RAB5A;SKI;ZEB2"]
["GO:0031410","cytoplasmic vesicle",0.111659704869408,0.54392820730034697,"ABCA1;CAMK2G;RAB5A;SREBF1;TAOK2;NRXN1;TNK2;TSSK2;SNX9"]
["GO:0030804","positive regulation of cyclic nucleotide biosynthetic process",0.111834311498031,0.54392820730034697,"ABCA1;GALR1"]
["GO:0071901","negative regulation of protein serine/threonine kinase activity",0.111834311498031,0.54392820730034697,"ABL1;KAT2B"]
["REACT:613","REACT: Meiosis",0.111834311498031,0.54392820730034697,"CDK2;CDK4"]
["GO:0004721","phosphoprotein phosphatase activity",0.114002053315105,0.54392820730034697,"CAMK2G;PPP3CB;PTPRD"]
["GO:0007269","neurotransmitter secretion",0.11401529288713801,0.54392820730034697,"PARK2;RIMS1"]
["GO:0009411","response to UV",0.11401529288713801,0.54392820730034697,"ERCC6;MAPK8"]
["GO:0030810","positive regulation of nucleotide biosynthetic process",0.11401529288713801,0.54392820730034697,"ABCA1;GALR1"]
["GO:0031331","positive regulation of cellular catabolic process",0.11401529288713801,0.54392820730034697,"CSNK1D;PIK3CB"]
["REACT:1276","REACT: p75 NTR receptor-mediated signalling",0.11401529288713801,0.54392820730034697,"ARHGDIA;MAPK8"]
["GO:0001782","B cell homeostasis",0.114449102186841,0.54392820730034697,"IKBKG"]
["GO:0002089","lens morphogenesis in camera-type eye",0.114449102186841,0.54392820730034697,"SKI"]
["GO:0006656","phosphatidylcholine biosynthetic process",0.114449102186841,0.54392820730034697,"PCYT1A"]
["GO:0007340","acrosome reaction",0.114449102186841,0.54392820730034697,"PLCB1"]
["GO:0010874","regulation of cholesterol efflux",0.114449102186841,0.54392820730034697,"ABCA1"]
["GO:0014009","glial cell proliferation",0.114449102186841,0.54392820730034697,"SKI"]
["GO:0031365","N-terminal protein amino acid modification",0.114449102186841,0.54392820730034697,"KAT2B"]
["GO:0032481","positive regulation of type I interferon production",0.114449102186841,0.54392820730034697,"TICAM1"]
["GO:0045736","negative regulation of cyclin-dependent protein kinase activity",0.114449102186841,0.54392820730034697,"KAT2B"]
["GO:0060351","cartilage development involved in endochondral bone morphogenesis",0.114449102186841,0.54392820730034697,"CBS"]
["GO:0060765","regulation of androgen receptor signaling pathway",0.114449102186841,0.54392820730034697,"ESR2"]
["GO:0070527","platelet aggregation",0.114449102186841,0.54392820730034697,"PIK3CB"]
["GO:0097035","regulation of membrane lipid distribution",0.114449102186841,0.54392820730034697,"ABCA1"]
["GO:0001772","immunological synapse",0.114449102186841,0.54392820730034697,"ARHGDIA"]
["GO:0001105","RNA polymerase II transcription coactivator activity",0.114449102186841,0.54392820730034697,"SMARCA2"]
["GO:0004970","ionotropic glutamate receptor activity",0.114449102186841,0.54392820730034697,"GRID2"]
["GO:0005001","transmembrane receptor protein tyrosine phosphatase activity",0.114449102186841,0.54392820730034697,"PTPRD"]
["GO:0005547","phosphatidylinositol-3,4,5-trisphosphate binding",0.114449102186841,0.54392820730034697,"PARD3"]
["GO:0008395","steroid hydroxylase activity",0.114449102186841,0.54392820730034697,"CYP7B1"]
["GO:0015464","acetylcholine receptor activity",0.114449102186841,0.54392820730034697,"CHRNA7"]
["GO:0016538","cyclin-dependent protein kinase regulator activity",0.114449102186841,0.54392820730034697,"KAT2B"]
["GO:0016775","phosphotransferase activity, nitrogenous group as acceptor",0.114449102186841,0.54392820730034697,"KCNH8"]
["GO:0019198","transmembrane receptor protein phosphatase activity",0.114449102186841,0.54392820730034697,"PTPRD"]
["GO:0030291","protein serine/threonine kinase inhibitor activity",0.114449102186841,0.54392820730034697,"KAT2B"]
["GO:0031490","chromatin DNA binding",0.114449102186841,0.54392820730034697,"ATOH1"]
["GO:0035004","phosphatidylinositol 3-kinase activity",0.114449102186841,0.54392820730034697,"PIK3CB"]
["GO:0070566","adenylyltransferase activity",0.114449102186841,0.54392820730034697,"ABL1"]
["GO:0072341","modified amino acid binding",0.114449102186841,0.54392820730034697,"CBS"]
["REACT:36","REACT: Activated AMPK stimulates fatty-acid oxidation in muscle",0.114449102186841,0.54392820730034697,"PRKAB2"]
["REACT:403","REACT: Frs2-mediated activation",0.114449102186841,0.54392820730034697,"MAPK3"]
["REACT:746","REACT: Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha",0.114449102186841,0.54392820730034697,"CUL2"]
["REACT:1079","REACT: Synthesis of PC",0.114449102186841,0.54392820730034697,"PCYT1A"]
["REACT:1146","REACT: Tie2 Signaling",0.114449102186841,0.54392820730034697,"PIK3CB"]
["NCI:30","NCI:BETACATENIN_DEG_PATHWAY",0.114449102186841,0.54392820730034697,"CSNK1D"]
["NCI:91","NCI:HIF1APATHWAY",0.114449102186841,0.54392820730034697,"CUL2"]
["GO:0000287","magnesium ion binding",0.115441128847228,0.54817195260331697,"ABL1;MAPK12;TSSK2"]
["GO:0001558","regulation of cell growth",0.115612518749868,0.54851496888873896,"ESR2;LIMK1;SMARCA2;TAOK2"]
["GO:0008610","lipid biosynthetic process",0.115932718760931,0.54945189927152005,"PCYT1A;PIK3CB;PRKAB2;SREBF1;LARGE;CYP7B1"]
["GO:0006200","ATP catabolic process",0.11620728889148201,0.54945189927152005,"PSMC2;CHD1L"]
["GO:0030801","positive regulation of cyclic nucleotide metabolic process",0.11620728889148201,0.54945189927152005,"ABCA1;GALR1"]
["GO:0060041","retina development in camera-type eye",0.11620728889148201,0.54945189927152005,"MAX;SKI"]
["GO:0010975","regulation of neuron projection development",0.116887122789299,0.55172317685187799,"ARHGDIA;LIMK1;SYNGAP1"]
["GO:0044445","cytosolic part",0.116887122789299,0.55172317685187799,"PIK3CB;RPL19;IKBKG"]
["REACT:454","REACT: Gene Expression",0.11718387437716,0.55265233849484197,"ERCC6;ESR2;KAT2B;MAPK11;MAPK3;PSMB1;PSMC2;RPL19;SKI;TBP"]
["GO:0009124","nucleoside monophosphate biosynthetic process",0.118339973440114,0.55463813691737396,"ABCA1;FLNA;GALR1"]
["REACT:652","REACT: Mitotic M-M/G1 phases",0.118339973440114,0.55463813691737396,"CDK2;PSMB1;PSMC2"]
["GO:0010563","negative regulation of phosphorus metabolic process",0.11841005633538,0.55463813691737396,"PARK2;KAT2B"]
["GO:0045936","negative regulation of phosphate metabolic process",0.11841005633538,0.55463813691737396,"PARK2;KAT2B"]
["GO:0051224","negative regulation of protein transport",0.11841005633538,0.55463813691737396,"FLNA;MAPK7"]
["GO:0042060","wound healing",0.119078660187209,0.55463813691737396,"ABL1;CDK2;ETS1;FLNA;PIK3CB;MAPK3;RAB5A"]
["GO:0005769","early endosome",0.119799618978459,0.55463813691737396,"MAPK3;RAB5A;SH3GL3"]
["GO:0007596","blood coagulation",0.120038065804125,0.55463813691737396,"ABL1;CDK2;FLNA;PIK3CB;MAPK3;RAB5A"]
["GO:0001958","endochondral ossification",0.120412220252669,0.55463813691737396,"CBS"]
["GO:0009083","branched chain family amino acid catabolic process",0.120412220252669,0.55463813691737396,"DBT"]
["GO:0014037","Schwann cell differentiation",0.120412220252669,0.55463813691737396,"SKI"]
["GO:0032735","positive regulation of interleukin-12 production",0.120412220252669,0.55463813691737396,"PLCB1"]
["GO:0036075","replacement ossification",0.120412220252669,0.55463813691737396,"CBS"]
["GO:0043030","regulation of macrophage activation",0.120412220252669,0.55463813691737396,"IL1RL1"]
["GO:0051445","regulation of meiotic cell cycle",0.120412220252669,0.55463813691737396,"PLCB1"]
["GO:0051646","mitochondrion localization",0.120412220252669,0.55463813691737396,"SYNJ2"]
["GO:0060135","maternal process involved in female pregnancy",0.120412220252669,0.55463813691737396,"CBS"]
["GO:0090003","regulation of establishment of protein localization in plasma membrane",0.120412220252669,0.55463813691737396,"NRXN1"]
["GO:0000803","sex chromosome",0.120412220252669,0.55463813691737396,"CDK2"]
["GO:0000062","fatty-acyl-CoA binding",0.120412220252669,0.55463813691737396,"DBI"]
["GO:0005234","extracellular-glutamate-gated ion channel activity",0.120412220252669,0.55463813691737396,"GRID2"]
["GO:0030159","receptor signaling complex scaffold activity",0.120412220252669,0.55463813691737396,"SHANK2"]
["GO:0035254","glutamate receptor binding",0.120412220252669,0.55463813691737396,"SHANK2"]
["GO:0045309","protein phosphorylated amino acid binding",0.120412220252669,0.55463813691737396,"MAPK3"]
["REACT:434","REACT: GABA synthesis, release, reuptake and degradation",0.120412220252669,0.55463813691737396,"RIMS1"]
["REACT:836","REACT: Prolonged ERK activation events",0.120412220252669,0.55463813691737396,"MAPK3"]
["REACT:1090","REACT: Synthesis of bile acids and bile salts",0.120412220252669,0.55463813691737396,"CYP7B1"]
["NCI:196","NCI:SMAD2_3PATHWAY",0.120412220252669,0.55463813691737396,"MAPK3"]
["GO:0008585","female gonad development",0.120623354759835,0.55468694807265895,"ESR2;UBE3A"]
["GO:0048863","stem cell differentiation",0.120623354759835,0.55468694807265895,"SKI;MSI2"]
["GO:0044087","regulation of cellular component biogenesis",0.121262911506996,0.55671659586076205,"LIMK1;PARK2;RAB5A;SNX9"]
["GO:0034330","cell junction organization",0.121265997471478,0.55671659586076205,"FLNA;TAOK2;PARD3"]
["GO:0009952","anterior/posterior pattern specification",0.122739046882923,0.563011946398283,"CRKL;SKI;ZEB2"]
["GO:0045981","positive regulation of nucleotide metabolic process",0.122846946397573,0.56304002276004295,"ABCA1;GALR1"]
["GO:0007599","hemostasis",0.12337448471511001,0.56442013761186305,"ABL1;CDK2;FLNA;PIK3CB;MAPK3;RAB5A"]
["GO:0050817","coagulation",0.12337448471511001,0.56442013761186305,"ABL1;CDK2;FLNA;PIK3CB;MAPK3;RAB5A"]
["GO:0045664","regulation of neuron differentiation",0.12355617979898199,0.56442013761186305,"ARHGDIA;ATOH1;LIMK1;SYNGAP1"]
["GO:0051129","negative regulation of cellular component organization",0.12355617979898199,0.56442013761186305,"ARHGDIA;PARK2;SKI;SYNGAP1"]
["GO:0042803","protein homodimerization activity",0.124215771974233,0.56696505821902499,"CBS;CHRNA7;FLNA;MAX;PLCB1;SNX9"]
["GO:0034599","cellular response to oxidative stress",0.12508059614827599,0.56866419815505198,"ETS1;SOD2"]
["GO:0046890","regulation of lipid biosynthetic process",0.12508059614827599,0.56866419815505198,"PRKAB2;SREBF1"]
["GO:0007005","mitochondrion organization",0.12570490984765401,0.56866419815505198,"PARK2;SOD2;SYNJ2"]
["GO:0009416","response to light stimulus",0.12570490984765401,0.56866419815505198,"ERCC6;MAPK8;SYNGAP1"]
["GO:0001963","synaptic transmission, dopaminergic",0.126335556676167,0.56866419815505198,"PARK2"]
["GO:0002825","regulation of T-helper 1 type immune response",0.126335556676167,0.56866419815505198,"IL1RL1"]
["GO:0006400","tRNA modification",0.126335556676167,0.56866419815505198,"WDR4"]
["GO:0034394","protein localization at cell surface",0.126335556676167,0.56866419815505198,"FLNA"]
["GO:0042491","auditory receptor cell differentiation",0.126335556676167,0.56866419815505198,"ATOH1"]
["GO:0046949","fatty-acyl-CoA biosynthetic process",0.126335556676167,0.56866419815505198,"DBT"]
["GO:0048665","neuron fate specification",0.126335556676167,0.56866419815505198,"ATOH1"]
["GO:0051489","regulation of filopodium assembly",0.126335556676167,0.56866419815505198,"RAB5A"]
["GO:0051881","regulation of mitochondrial membrane potential",0.126335556676167,0.56866419815505198,"SOD2"]
["GO:0005669","transcription factor TFIID complex",0.126335556676167,0.56866419815505198,"TBP"]
["GO:0005839","proteasome core complex",0.126335556676167,0.56866419815505198,"PSMB1"]
["GO:0031672","A band",0.126335556676167,0.56866419815505198,"KAT2B"]
["REACT:413","REACT: G beta:gamma signalling through PLC beta",0.126335556676167,0.56866419815505198,"PLCB1"]
["GO:0044057","regulation of system process",0.126609075233726,0.56896945913320396,"CAMK2G;PARK2;PPP3CB;SYNGAP1;NRXN1"]
["GO:0048514","blood vessel morphogenesis",0.126609075233726,0.56896945913320396,"CHRNA7;ETS1;MAPK7;NRXN3;NRXN1"]
["KEGG:05016","Huntington's disease",0.127197598883841,0.57032936343069596,"PLCB1;SOD2;TBP"]
["GO:0042594","response to starvation",0.127324071554033,0.57032936343069596,"MAX;SREBF1"]
["GO:0046474","glycerophospholipid biosynthetic process",0.127324071554033,0.57032936343069596,"PCYT1A;PIK3CB"]
["GO:0042393","histone binding",0.127324071554033,0.57032936343069596,"BAZ1B;UHRF1"]
["GO:0005912","adherens junction",0.12869670981985201,0.57601148764030596,"MAPK3;TNK2;PARD3"]
["GO:0001838","embryonic epithelial tube formation",0.129577142774987,0.57638895113128796,"SKI;ZEB2"]
["GO:0009566","fertilization",0.129577142774987,0.57638895113128796,"UBE3A;PLCB1"]
["KEGG:04064","NF-kappa B signaling pathway",0.129577142774987,0.57638895113128796,"IKBKG;TICAM1"]
["GO:0016881","acid-amino acid ligase activity",0.13054689469686601,0.57638895113128796,"PARK2;UBE3A;TRIP12;UBE2W"]
["GO:0008360","regulation of cell shape",0.13183958256519099,0.57638895113128796,"TAOK2;CYFIP1"]
["GO:0032320","positive regulation of Ras GTPase activity",0.13183958256519099,0.57638895113128796,"SYNGAP1;RALGAPA1"]
["GO:0051092","positive regulation of NF-kappaB transcription factor activity",0.13183958256519099,0.57638895113128796,"IKBKG;TICAM1"]
["GO:0072175","epithelial tube formation",0.13183958256519099,0.57638895113128796,"SKI;ZEB2"]
["GO:0048610","cellular process involved in reproduction",0.131915073218906,0.57638895113128796,"CDK2;ESR2;RPL19;UBE3A;PLCB1;TSSK2"]
["GO:0001504","neurotransmitter uptake",0.13221937436471501,0.57638895113128796,"PARK2"]
["GO:0001539","ciliary or flagellar motility",0.13221937436471501,0.57638895113128796,"RFX3"]
["GO:0022408","negative regulation of cell-cell adhesion",0.13221937436471501,0.57638895113128796,"MAPK7"]
["GO:0032370","positive regulation of lipid transport",0.13221937436471501,0.57638895113128796,"ABCA1"]
["GO:0035384","thioester biosynthetic process",0.13221937436471501,0.57638895113128796,"DBT"]
["GO:0043647","inositol phosphate metabolic process",0.13221937436471501,0.57638895113128796,"SYNJ2"]
["GO:0045123","cellular extravasation",0.13221937436471501,0.57638895113128796,"PLCB1"]
["GO:0045773","positive regulation of axon extension",0.13221937436471501,0.57638895113128796,"LIMK1"]
["GO:0050702","interleukin-1 beta secretion",0.13221937436471501,0.57638895113128796,"ABCA1"]
["GO:0055093","response to hyperoxia",0.13221937436471501,0.57638895113128796,"SOD2"]
["GO:0071616","acyl-CoA biosynthetic process",0.13221937436471501,0.57638895113128796,"DBT"]
["GO:0008023","transcription elongation factor complex",0.13221937436471501,0.57638895113128796,"ERCC6"]
["GO:0004298","threonine-type endopeptidase activity",0.13221937436471501,0.57638895113128796,"PSMB1"]
["GO:0004683","calmodulin-dependent protein kinase activity",0.13221937436471501,0.57638895113128796,"CAMK2G"]
["GO:0005246","calcium channel regulator activity",0.13221937436471501,0.57638895113128796,"NRXN1"]
["GO:0005545","1-phosphatidylinositol binding",0.13221937436471501,0.57638895113128796,"SNX9"]
["GO:0042165","neurotransmitter binding",0.13221937436471501,0.57638895113128796,"CHRNA7"]
["GO:0070003","threonine-type peptidase activity",0.13221937436471501,0.57638895113128796,"PSMB1"]
["REACT:823","REACT: Presynaptic function of Kainate receptors",0.13221937436471501,0.57638895113128796,"PLCB1"]
["REACT:987","REACT: SHC1 events in ERBB4 signaling",0.13221937436471501,0.57638895113128796,"MAPK3"]
["NCI:152","NCI:P38_MK2PATHWAY",0.13221937436471501,0.57638895113128796,"MAPK11"]
["NCI:160","NCI:PDGFRAPATHWAY",0.13221937436471501,0.57638895113128796,"CRKL"]
["NCI:187","NCI:RXR_VDR_PATHWAY",0.13221937436471501,0.57638895113128796,"ABCA1"]
["NCI:189","NCI:S1P_S1P1_PATHWAY",0.13221937436471501,0.57638895113128796,"MAPK3"]
["GO:0009314","response to radiation",0.132913418111442,0.57895829054527403,"ERCC6;MAPK8;SOD2;SYNGAP1"]
["GO:0044271","cellular nitrogen compound biosynthetic process",0.133656906743053,0.58173879473058199,"ABCA1;CBS;FLNA;GALR1;SOD2;TICAM1"]
["GO:0002474","antigen processing and presentation of peptide antigen via MHC class I",0.13411116624866001,0.58279887799496399,"PSMB1;PSMC2"]
["GO:0048638","regulation of developmental growth",0.13411116624866001,0.58279887799496399,"LIMK1;PLCB1"]
["GO:0002520","immune system development",0.13453198610268999,0.58416871830461603,"CRKL;ETS1;PPP3CB;SOD2;KLF13;SMAP1"]
["GO:0031982","vesicle",0.13509895234866101,0.58617051324924696,"ABCA1;CAMK2G;RAB5A;SREBF1;TAOK2;NRXN1;TNK2;TSSK2;SNX9"]
["GO:0051130","positive regulation of cellular component organization",0.13552191318391499,0.58754484618606195,"ARHGDIA;LIMK1;MAPK3;NRXN1;SNX9"]
["GO:0006606","protein import into nucleus",0.13628640597835001,0.590239324327407,"FLNA;MAPK3;MAPK7"]
["GO:0007218","neuropeptide signaling pathway",0.13639167169562899,0.590239324327407,"GALR1;NTSR2"]
["GO:0009081","branched chain family amino acid metabolic process",0.138063934504639,0.590239324327407,"DBT"]
["GO:0015872","dopamine transport",0.138063934504639,0.590239324327407,"PARK2"]
["GO:0017158","regulation of calcium ion-dependent exocytosis",0.138063934504639,0.590239324327407,"PLCB1"]
["GO:0021772","olfactory bulb development",0.138063934504639,0.590239324327407,"SKI"]
["GO:0021988","olfactory lobe development",0.138063934504639,0.590239324327407,"SKI"]
["GO:0032720","negative regulation of tumor necrosis factor production",0.138063934504639,0.590239324327407,"CHRNA7"]
["GO:0032784","regulation of transcription elongation, DNA-dependent",0.138063934504639,0.590239324327407,"ERCC6"]
["GO:0035337","fatty-acyl-CoA metabolic process",0.138063934504639,0.590239324327407,"DBT"]
["GO:0048169","regulation of long-term neuronal synaptic plasticity",0.138063934504639,0.590239324327407,"SYNGAP1"]
["GO:0090207","regulation of triglyceride metabolic process",0.138063934504639,0.590239324327407,"SREBF1"]
["GO:0043596","nuclear replication fork",0.138063934504639,0.590239324327407,"BAZ1B"]
["REACT:704","REACT: Nephrin interactions",0.138063934504639,0.590239324327407,"PIK3CB"]
["REACT:1111","REACT: TRAF6 mediated NF-kB activation",0.138063934504639,0.590239324327407,"IKBKG"]
["KEGG:04710","Circadian rhythm - mammal",0.138063934504639,0.590239324327407,"CSNK1D"]
["NCI:10","NCI:ANTHRAXPATHWAY",0.138063934504639,0.590239324327407,"MAPK3"]
["NCI:137","NCI:MYC_PATHWAY",0.138063934504639,0.590239324327407,"MAX"]
["GO:0050852","T cell receptor signaling pathway",0.138680879299002,0.59196190145222305,"PIK3CB;IKBKG"]
["GO:0050880","regulation of blood vessel size",0.138680879299002,0.59196190145222305,"CBS;SOD2"]
["GO:0007015","actin filament organization",0.13936504889389101,0.59442363182806901,"FLNA;LIMK1;PARK2"]
["GO:0031967","organelle envelope",0.139510987389041,0.59458765965807203,"ABL1;CDK4;SOD2;SREBF1;SYNJ2;PMPCB;WTAP;CEP70"]
["GO:0009968","negative regulation of signal transduction",0.140734466004968,0.59807780677375399,"ESR2;SKI;SYNGAP1;IL1RL1;CYP7B1;SNX14"]
["GO:0051170","nuclear import",0.14091328356226801,0.59807780677375399,"FLNA;MAPK3;MAPK7"]
["GO:0035150","regulation of tube size",0.14097857195100799,0.59807780677375399,"CBS;SOD2"]
["GO:0009898","internal side of plasma membrane",0.14097857195100799,0.59807780677375399,"SYNGAP1;SNX9"]
["GO:0008757","S-adenosylmethionine-dependent methyltransferase activity",0.14097857195100799,0.59807780677375399,"WDR4;EHMT1"]
["GO:0019902","phosphatase binding",0.14097857195100799,0.59807780677375399,"PPP3CB;MAPK3"]
["GO:0010564","regulation of cell cycle process",0.14161715933883301,0.59841056769801804,"CDK2;PSMB1;PSMC2;TAOK2;PLCB1"]
["GO:0022612","gland morphogenesis",0.14328453502003999,0.59841056769801804,"ESR2;CYP7B1"]
["GO:0046545","development of primary female sexual characteristics",0.14328453502003999,0.59841056769801804,"ESR2;UBE3A"]
["GO:0004519","endonuclease activity",0.14328453502003999,0.59841056769801804,"RNASE1;RNASE6"]
["GO:0002009","morphogenesis of an epithelium",0.14377990589610001,0.59841056769801804,"ESR2;SKI;CYP7B1;ZEB2"]
["GO:0006041","glucosamine metabolic process",0.143869496572372,0.59841056769801804,"LARGE"]
["GO:0006044","N-acetylglucosamine metabolic process",0.143869496572372,0.59841056769801804,"LARGE"]
["GO:0006298","mismatch repair",0.143869496572372,0.59841056769801804,"ABL1"]
["GO:0010470","regulation of gastrulation",0.143869496572372,0.59841056769801804,"MAPK7"]
["GO:0021846","cell proliferation in forebrain",0.143869496572372,0.59841056769801804,"ZEB2"]
["GO:0032648","regulation of interferon-beta production",0.143869496572372,0.59841056769801804,"TICAM1"]
["GO:0032924","activin receptor signaling pathway",0.143869496572372,0.59841056769801804,"SKI"]
["GO:0038061","NIK/NF-kappaB cascade",0.143869496572372,0.59841056769801804,"IKBKG"]
["GO:0042554","superoxide anion generation",0.143869496572372,0.59841056769801804,"SOD2"]
["GO:0043462","regulation of ATPase activity",0.143869496572372,0.59841056769801804,"UHRF1"]
["GO:0050701","interleukin-1 secretion",0.143869496572372,0.59841056769801804,"ABCA1"]
["GO:0070534","protein K63-linked ubiquitination",0.143869496572372,0.59841056769801804,"PARK2"]
["GO:0090199","regulation of release of cytochrome c from mitochondria",0.143869496572372,0.59841056769801804,"PARK2"]
["GO:0005891","voltage-gated calcium channel complex",0.143869496572372,0.59841056769801804,"CACNA1B"]
["GO:0001046","core promoter sequence-specific DNA binding",0.143869496572372,0.59841056769801804,"ESR2"]
["GO:0001540","beta-amyloid binding",0.143869496572372,0.59841056769801804,"CHRNA7"]
["GO:0015485","cholesterol binding",0.143869496572372,0.59841056769801804,"ABCA1"]
["REACT:316","REACT: Downregulation of SMAD2/3:SMAD4 transcriptional activity",0.143869496572372,0.59841056769801804,"SKI"]
["REACT:440","REACT: GRB2 events in ERBB2 signaling",0.143869496572372,0.59841056769801804,"MAPK3"]
["REACT:1012","REACT: Signaling by BMP",0.143869496572372,0.59841056769801804,"SKI"]
["NCI:147","NCI:NFKAPPABCANONICALPATHWAY",0.143869496572372,0.59841056769801804,"IKBKG"]
["GO:0006354","transcription elongation, DNA-dependent",0.145598556327698,0.60378651694514696,"ERCC6;TBP"]
["GO:0008277","regulation of G-protein coupled receptor protein signaling pathway",0.145598556327698,0.60378651694514696,"PLCB1;SNX14"]
["GO:0009636","response to toxin",0.145598556327698,0.60378651694514696,"ERCC6;MAPK3"]
["GO:0035148","tube formation",0.145598556327698,0.60378651694514696,"SKI;ZEB2"]
["GO:0071822","protein complex subunit organization",0.146929863235361,0.60885093888990005,"MAX;MAPK3;RPL19;SKI;SOD2;RIMS1;SNX9;PARD3"]
["GO:0034762","regulation of transmembrane transport",0.147164180993862,0.60936545603147096,"CACNA1B;FLNA;MAPK7"]
["GO:0002274","myeloid leukocyte activation",0.14792042612601999,0.60969015231887902,"IL1RL1;TICAM1"]
["GO:0055002","striated muscle cell development",0.14792042612601999,0.60969015231887902,"SKI;PLCB1"]
["GO:0019717","synaptosome",0.14792042612601999,0.60969015231887902,"GRID2;CYFIP1"]
["GO:0006461","protein complex assembly",0.148013821943628,0.60969015231887902,"MAX;MAPK3;SKI;SOD2;RIMS1;SNX9;PARD3"]
["GO:0006890","retrograde vesicle-mediated transport, Golgi to ER",0.149636318345539,0.60969015231887902,"RER1"]
["GO:0007157","heterophilic cell-cell adhesion",0.149636318345539,0.60969015231887902,"NRXN1"]
["GO:0007212","dopamine receptor signaling pathway",0.149636318345539,0.60969015231887902,"FLNA"]
["GO:0010165","response to X-ray",0.149636318345539,0.60969015231887902,"ERCC6"]
["GO:0021587","cerebellum morphogenesis",0.149636318345539,0.60969015231887902,"CBS"]
["GO:0032856","activation of Ras GTPase activity",0.149636318345539,0.60969015231887902,"RALGAPA1"]
["GO:0046928","regulation of neurotransmitter secretion",0.149636318345539,0.60969015231887902,"PARK2"]
["GO:0051220","cytoplasmic sequestering of protein",0.149636318345539,0.60969015231887902,"FLNA"]
["GO:0060397","JAK-STAT cascade involved in growth hormone signaling pathway",0.149636318345539,0.60969015231887902,"MAPK3"]
["GO:0005844","polysome",0.149636318345539,0.60969015231887902,"MSI2"]
["GO:0001190","RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription",0.149636318345539,0.60969015231887902,"SMARCA2"]
["GO:0046875","ephrin receptor binding",0.149636318345539,0.60969015231887902,"ANKS1B"]
["REACT:274","REACT: DARPP-32 events",0.149636318345539,0.60969015231887902,"PPP3CB"]
["REACT:480","REACT: Growth hormone receptor signaling",0.149636318345539,0.60969015231887902,"MAPK3"]
["REACT:999","REACT: Sema4D induced cell migration and growth-cone collapse",0.149636318345539,0.60969015231887902,"LIMK1"]
["REACT:1070","REACT: Sulfur amino acid metabolism",0.149636318345539,0.60969015231887902,"CBS"]
["REACT:1102","REACT: TAK1 activates NFkB by phosphorylation and activation of IKKs complex",0.149636318345539,0.60969015231887902,"IKBKG"]
["GO:0070271","protein complex biogenesis",0.149667249972711,0.60969015231887902,"MAX;MAPK3;SKI;SOD2;RIMS1;SNX9;PARD3"]
["GO:0048469","cell maturation",0.150249937074903,0.61146305487606201,"ESR2;RFX3"]
["GO:0046879","hormone secretion",0.15032352759064399,0.61146305487606201,"CAMK2G;PPP3CB;RFX3"]
["REACT:280","REACT: DNA Replication",0.15191145615124299,0.61746816710409702,"CDK2;PSMB1;PSMC2"]
["GO:0019221","cytokine-mediated signaling pathway",0.152468180053078,0.61922638279155695,"CAMK2G;MAPK3;IL1RL1;PLCB1"]
["GO:0043933","macromolecular complex subunit organization",0.15256788860175199,0.61922638279155695,"ABCA1;MAX;MAPK3;RPL19;SKI;SOD2;BAZ1B;RIMS1;SNX9;PARD3"]
["GO:0034284","response to monosaccharide stimulus",0.15493106496908601,0.62280962066384604,"PPP3CB;PLCB1"]
["GO:0046660","female sex differentiation",0.15493106496908601,0.62280962066384604,"ESR2;UBE3A"]
["GO:0003705","sequence-specific distal enhancer binding RNA polymerase II transcription factor activity",0.15493106496908601,0.62280962066384604,"RFX3;KCNH8"]
["GO:0070161","anchoring junction",0.15510351099675301,0.62280962066384604,"MAPK3;TNK2;PARD3"]
["GO:0032608","interferon-beta production",0.155364655913975,0.62280962066384604,"TICAM1"]
["GO:0043489","RNA stabilization",0.155364655913975,0.62280962066384604,"SYNCRIP"]
["GO:0045494","photoreceptor cell maintenance",0.155364655913975,0.62280962066384604,"ERCC6"]
["GO:0048255","mRNA stabilization",0.155364655913975,0.62280962066384604,"SYNCRIP"]
["GO:0051602","response to electrical stimulus",0.155364655913975,0.62280962066384604,"SOD2"]
["GO:0051966","regulation of synaptic transmission, glutamatergic",0.155364655913975,0.62280962066384604,"NRXN1"]
["GO:0012507","ER to Golgi transport vesicle membrane",0.155364655913975,0.62280962066384604,"SREBF1"]
["REACT:217","REACT: Cellular response to hypoxia",0.155364655913975,0.62280962066384604,"CUL2"]
["REACT:218","REACT: Cellular responses to stress",0.155364655913975,0.62280962066384604,"CUL2"]
["REACT:418","REACT: G0 and Early G1",0.155364655913975,0.62280962066384604,"CDK2"]
["REACT:912","REACT: Regulation of Hypoxia-inducible Factor (HIF) by Oxygen",0.155364655913975,0.62280962066384604,"CUL2"]
["REACT:986","REACT: SHC1 events in ERBB2 signaling",0.155364655913975,0.62280962066384604,"MAPK3"]
["NCI:5","NCI:ALK1PATHWAY",0.155364655913975,0.62280962066384604,"MAPK3"]
["GO:0048002","antigen processing and presentation of peptide antigen",0.15728227907291301,0.62947737338287202,"PSMB1;PSMC2"]
["GO:0035257","nuclear hormone receptor binding",0.15728227907291301,0.62947737338287202,"BAZ1B;TRIP12"]
["GO:0006520","cellular amino acid metabolic process",0.157369343345718,0.62947737338287202,"CBS;DBT;PSMB1;PSMC2;SOD2"]
["GO:0009617","response to bacterium",0.15752179315755799,0.62963190733208696,"ABCA1;MAPK3;SOD2;TICAM1"]
["GO:0009063","cellular amino acid catabolic process",0.159640328600509,0.63413163895855496,"CBS;DBT"]
["GO:0045761","regulation of adenylate cyclase activity",0.159640328600509,0.63413163895855496,"FLNA;GALR1"]
["GO:0001666","response to hypoxia",0.15993115054118701,0.63413163895855496,"CHRNA7;ETS1;SOD2"]
["GO:0009914","hormone transport",0.15993115054118701,0.63413163895855496,"CAMK2G;PPP3CB;RFX3"]
["REACT:787","REACT: Phospholipid metabolism",0.15993115054118701,0.63413163895855496,"PCYT1A;PIK3CB;SYNJ2"]
["REACT:796","REACT: Platelet activation, signaling and aggregation",0.15993115054118701,0.63413163895855496,"FLNA;MAPK3;PIK3CB"]
["GO:0006699","bile acid biosynthetic process",0.16105476369066701,0.63413163895855496,"CYP7B1"]
["GO:0035065","regulation of histone acetylation",0.16105476369066701,0.63413163895855496,"MAPK3"]
["GO:0042417","dopamine metabolic process",0.16105476369066701,0.63413163895855496,"PARK2"]
["GO:0043029","T cell homeostasis",0.16105476369066701,0.63413163895855496,"PPP3CB"]
["GO:0043502","regulation of muscle adaptation",0.16105476369066701,0.63413163895855496,"CAMK2G"]
["GO:0045599","negative regulation of fat cell differentiation",0.16105476369066701,0.63413163895855496,"SOD2"]
["GO:0070979","protein K11-linked ubiquitination",0.16105476369066701,0.63413163895855496,"UBE2W"]
["GO:0071560","cellular response to transforming growth factor beta stimulus",0.16105476369066701,0.63413163895855496,"MAPK7"]
["GO:0005771","multivesicular body",0.16105476369066701,0.63413163895855496,"STEAP3"]
["GO:0008066","glutamate receptor activity",0.16105476369066701,0.63413163895855496,"GRID2"]
["GO:0008173","RNA methyltransferase activity",0.16105476369066701,0.63413163895855496,"WDR4"]
["GO:0019003","GDP binding",0.16105476369066701,0.63413163895855496,"RAB5A"]
["REACT:884","REACT: RNA Polymerase III Transcription Initiation From Type 2 Promoter",0.16105476369066701,0.63413163895855496,"TBP"]
["REACT:887","REACT: RORA Activates Circadian Expression",0.16105476369066701,0.63413163895855496,"SREBF1"]
["REACT:1242","REACT: YAP1- and WWTR1 (TAZ)-stimulated gene expression",0.16105476369066701,0.63413163895855496,"KAT2B"]
["GO:0016573","histone acetylation",0.16200501791896399,0.63741945883905204,"MAPK3;KAT2B"]
["GO:0005874","microtubule",0.16263779657567901,0.63945436436152003,"CSNK1D;SYNJ2;STAU2;TUBGCP5"]
["GO:0031279","regulation of cyclase activity",0.16437615367168301,0.64061153444185803,"FLNA;GALR1"]
["REACT:483","REACT: HIV Infection",0.16480476268497801,0.64061153444185803,"PSMB1;PSMC2;TBP"]
["GO:0006066","alcohol metabolic process",0.16490749751075201,0.64061153444185803,"ABCA1;PARK2;PCYT1A;SREBF1;LARGE;CYP7B1"]
["GO:0032101","regulation of response to external stimulus",0.16651464461197801,0.64061153444185803,"GRID2;MAPK7;IL1RL1;NRXN1"]
["GO:0022836","gated channel activity",0.16651464461197801,0.64061153444185803,"CACNA1B;CHRNA7;GRID2;KCNH8"]
["GO:0001975","response to amphetamine",0.16670689442263401,0.64061153444185803,"PPP3CB"]
["GO:0006040","amino sugar metabolic process",0.16670689442263401,0.64061153444185803,"LARGE"]
["GO:0010743","regulation of macrophage derived foam cell differentiation",0.16670689442263401,0.64061153444185803,"ABCA1"]
["GO:0014014","negative regulation of gliogenesis",0.16670689442263401,0.64061153444185803,"SKI"]
["GO:0016079","synaptic vesicle exocytosis",0.16670689442263401,0.64061153444185803,"RIMS1"]
["GO:0016339","calcium-dependent cell-cell adhesion",0.16670689442263401,0.64061153444185803,"NRXN1"]
["GO:0021575","hindbrain morphogenesis",0.16670689442263401,0.64061153444185803,"CBS"]
["GO:0032722","positive regulation of chemokine production",0.16670689442263401,0.64061153444185803,"IL1RL1"]
["GO:0035690","cellular response to drug",0.16670689442263401,0.64061153444185803,"PPP3CB"]
["GO:0043124","negative regulation of I-kappaB kinase/NF-kappaB cascade",0.16670689442263401,0.64061153444185803,"IL1RL1"]
["GO:0046580","negative regulation of Ras protein signal transduction",0.16670689442263401,0.64061153444185803,"SYNGAP1"]
["GO:0051298","centrosome duplication",0.16670689442263401,0.64061153444185803,"CDK2"]
["GO:0051865","protein autoubiquitination",0.16670689442263401,0.64061153444185803,"PARK2"]
["GO:0060761","negative regulation of response to cytokine stimulus",0.16670689442263401,0.64061153444185803,"MAPK7"]
["GO:0033017","sarcoplasmic reticulum membrane",0.16670689442263401,0.64061153444185803,"CAMK2G"]
["GO:0070461","SAGA-type complex",0.16670689442263401,0.64061153444185803,"KAT2B"]
["GO:0000987","core promoter proximal region sequence-specific DNA binding",0.16670689442263401,0.64061153444185803,"UHRF1"]
["GO:0030546","receptor activator activity",0.16670689442263401,0.64061153444185803,"BAZ1B"]
["REACT:159","REACT: Bile acid and bile salt metabolism",0.16670689442263401,0.64061153444185803,"CYP7B1"]
["REACT:188","REACT: CREB phosphorylation through the activation of Ras",0.16670689442263401,0.64061153444185803,"CAMK2G"]
["REACT:883","REACT: RNA Polymerase III Transcription Initiation From Type 1 Promoter",0.16670689442263401,0.64061153444185803,"TBP"]
["REACT:1171","REACT: Transferrin endocytosis and recycling",0.16670689442263401,0.64061153444185803,"STEAP3"]
["REACT:1266","REACT: mTOR signalling",0.16670689442263401,0.64061153444185803,"PRKAB2"]
["GO:0010212","response to ionizing radiation",0.1667535447571,0.64061153444185803,"ERCC6;SOD2"]
["GO:0018393","internal peptidyl-lysine acetylation",0.1667535447571,0.64061153444185803,"MAPK3;KAT2B"]
["GO:0031346","positive regulation of cell projection organization",0.1667535447571,0.64061153444185803,"ARHGDIA;LIMK1"]
["GO:0030027","lamellipodium",0.1667535447571,0.64061153444185803,"RAC3;CYFIP1"]
["REACT:770","REACT: PPARA Activates Gene Expression",0.1667535447571,0.64061153444185803,"ABCA1;SREBF1"]
["GO:0007188","G-protein signaling, coupled to cAMP nucleotide second messenger",0.16913700230756801,0.64629249300606995,"FLNA;GALR1"]
["GO:0009896","positive regulation of catabolic process",0.16913700230756801,0.64629249300606995,"CSNK1D;PIK3CB"]
["GO:0042306","regulation of protein import into nucleus",0.16913700230756801,0.64629249300606995,"FLNA;MAPK7"]
["GO:0050769","positive regulation of neurogenesis",0.16913700230756801,0.64629249300606995,"ARHGDIA;LIMK1"]
["GO:0016879","ligase activity, forming carbon-nitrogen bonds",0.170424782882277,0.64629249300606995,"PARK2;UBE3A;TRIP12;UBE2W"]
["GO:0001818","negative regulation of cytokine production",0.171526339668437,0.64629249300606995,"CHRNA7;IL1RL1"]
["GO:0018394","peptidyl-lysine acetylation",0.171526339668437,0.64629249300606995,"MAPK3;KAT2B"]
["GO:0045444","fat cell differentiation",0.171526339668437,0.64629249300606995,"SOD2;PLCB1"]
["GO:0051339","regulation of lyase activity",0.171526339668437,0.64629249300606995,"FLNA;GALR1"]
["GO:0005099","Ras GTPase activator activity",0.171526339668437,0.64629249300606995,"SYNGAP1;RALGAPA1"]
["GO:0051301","cell division",0.17158373597377,0.64629249300606995,"CDK2;CDK4;PIK3CB;SMC2;PARD3"]
["GO:0048471","perinuclear region of cytoplasm",0.17158373597377,0.64629249300606995,"ABL1;CSNK1D;PARK2;SYNJ2;CYFIP1"]
["GO:0010629","negative regulation of gene expression",0.17194612741354501,0.64629249300606995,"CDK2;ESR2;MAX;RFX3;SKI;SMARCA2;PLCB1;EHMT1"]
["GO:0010821","regulation of mitochondrion organization",0.17232129920172701,0.64629249300606995,"PARK2"]
["GO:0030514","negative regulation of BMP signaling pathway",0.17232129920172701,0.64629249300606995,"SKI"]
["GO:0031058","positive regulation of histone modification",0.17232129920172701,0.64629249300606995,"MAPK3"]
["GO:0042304","regulation of fatty acid biosynthetic process",0.17232129920172701,0.64629249300606995,"PRKAB2"]
["GO:0051058","negative regulation of small GTPase mediated signal transduction",0.17232129920172701,0.64629249300606995,"SYNGAP1"]
["GO:0070206","protein trimerization",0.17232129920172701,0.64629249300606995,"SKI"]
["GO:0071825","protein-lipid complex subunit organization",0.17232129920172701,0.64629249300606995,"ABCA1"]
["GO:0071827","plasma lipoprotein particle organization",0.17232129920172701,0.64629249300606995,"ABCA1"]
["GO:2000756","regulation of peptidyl-lysine acetylation",0.17232129920172701,0.64629249300606995,"MAPK3"]
["GO:0030134","ER to Golgi transport vesicle",0.17232129920172701,0.64629249300606995,"SREBF1"]
["GO:0043198","dendritic shaft",0.17232129920172701,0.64629249300606995,"SYNGAP1"]
["GO:0043209","myelin sheath",0.17232129920172701,0.64629249300606995,"PARD3"]
["GO:0071339","MLL1 complex",0.17232129920172701,0.64629249300606995,"MAX"]
["GO:0001159","core promoter proximal region DNA binding",0.17232129920172701,0.64629249300606995,"UHRF1"]
["REACT:323","REACT: Dual incision reaction in TC-NER",0.17232129920172701,0.64629249300606995,"ERCC6"]
["REACT:399","REACT: Formation of transcription-coupled NER (TC-NER) repair complex",0.17232129920172701,0.64629249300606995,"ERCC6"]
["REACT:416","REACT: G-protein beta:gamma signalling",0.17232129920172701,0.64629249300606995,"PLCB1"]
["REACT:566","REACT: Interleukin receptor SHC signaling",0.17232129920172701,0.64629249300606995,"PIK3CB"]
["REACT:764","REACT: PKB-mediated events",0.17232129920172701,0.64629249300606995,"PRKAB2"]
["REACT:885","REACT: RNA Polymerase III Transcription Initiation From Type 3 Promoter",0.17232129920172701,0.64629249300606995,"TBP"]
["NCI:99","NCI:IGF1_PATHWAY",0.17232129920172701,0.64629249300606995,"CRKL"]
["NCI:220","NCI:VEGFR1_PATHWAY",0.17232129920172701,0.64629249300606995,"MAPK3"]
["REACT:922","REACT: Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)",0.17392137237729999,0.65185164769053205,"ABCA1;SREBF1"]
["GO:0034504","protein localization to nucleus",0.174683200078599,0.65426368506080501,"FLNA;MAPK3;MAPK7"]
["GO:0021915","neural tube development",0.17632191814341699,0.65638357570629102,"SKI;ZEB2"]
["GO:0008542","visual learning",0.17789822747536799,0.65638357570629102,"SYNGAP1"]
["GO:0009069","serine family amino acid metabolic process",0.17789822747536799,0.65638357570629102,"CBS"]
["GO:0042088","T-helper 1 type immune response",0.17789822747536799,0.65638357570629102,"IL1RL1"]
["GO:0043044","ATP-dependent chromatin remodeling",0.17789822747536799,0.65638357570629102,"BAZ1B"]
["GO:0045668","negative regulation of osteoblast differentiation",0.17789822747536799,0.65638357570629102,"SKI"]
["GO:0048009","insulin-like growth factor receptor signaling pathway",0.17789822747536799,0.65638357570629102,"PLCB1"]
["GO:0071326","cellular response to monosaccharide stimulus",0.17789822747536799,0.65638357570629102,"PPP3CB"]
["GO:0071331","cellular response to hexose stimulus",0.17789822747536799,0.65638357570629102,"PPP3CB"]
["GO:0071333","cellular response to glucose stimulus",0.17789822747536799,0.65638357570629102,"PPP3CB"]
["GO:0090002","establishment of protein localization in plasma membrane",0.17789822747536799,0.65638357570629102,"NRXN1"]
["GO:0016234","inclusion body",0.17789822747536799,0.65638357570629102,"PARK2"]
["GO:0005548","phospholipid transporter activity",0.17789822747536799,0.65638357570629102,"ABCA1"]
["REACT:599","REACT: Lipoprotein metabolism",0.17789822747536799,0.65638357570629102,"ABCA1"]
["REACT:998","REACT: Sema4D in semaphorin signaling",0.17789822747536799,0.65638357570629102,"LIMK1"]
["KEGG:05216","Thyroid cancer",0.17789822747536799,0.65638357570629102,"MAPK3"]
["NCI:28","NCI:BARD1PATHWAY",0.17789822747536799,0.65638357570629102,"CDK2"]
["NCI:39","NCI:CDC42_REG_PATHWAY",0.17789822747536799,0.65638357570629102,"ARHGDIA"]
["NCI:191","NCI:S1P_S1P3_PATHWAY",0.17789822747536799,0.65638357570629102,"MAPK3"]
["GO:0005819","spindle",0.17801307871411101,0.65638357570629102,"CSNK1D;PARD3;TUBGCP5"]
["GO:0000981","sequence-specific DNA binding RNA polymerase II transcription factor activity",0.17801307871411101,0.65638357570629102,"ESR2;RFX3;KCNH8"]
["GO:0001817","regulation of cytokine production",0.178341797034892,0.65638357570629102,"CHRNA7;IL1RL1;PLCB1;TICAM1"]
["GO:0042493","response to drug",0.178341797034892,0.65638357570629102,"CDK4;PPP3CB;SOD2;CYP7B1"]
["GO:0010648","negative regulation of cell communication",0.17862244483276199,0.65638357570629102,"ESR2;SKI;SYNGAP1;IL1RL1;CYP7B1;SNX14"]
["GO:0023057","negative regulation of signaling",0.17862244483276199,0.65638357570629102,"ESR2;SKI;SYNGAP1;IL1RL1;CYP7B1;SNX14"]
["GO:0003018","vascular process in circulatory system",0.17872779682730799,0.65638357570629102,"CBS;SOD2"]
["GO:0006475","internal protein amino acid acetylation",0.17872779682730799,0.65638357570629102,"MAPK3;KAT2B"]
["GO:0005506","iron ion binding",0.181360671460573,0.65638357570629102,"CBS;CYP7B1;STEAP3"]
["GO:0030099","myeloid cell differentiation",0.18304095787934799,0.65638357570629102,"ETS1;KLF13;SMAP1"]
["GO:0030168","platelet activation",0.18304095787934799,0.65638357570629102,"FLNA;PIK3CB;MAPK3"]
["GO:0003333","amino acid transmembrane transport",0.18343792705721401,0.65638357570629102,"PRKAB2"]
["GO:0007040","lysosome organization",0.18343792705721401,0.65638357570629102,"ABCA1"]
["GO:0010742","macrophage derived foam cell differentiation",0.18343792705721401,0.65638357570629102,"ABCA1"]
["GO:0014047","glutamate secretion",0.18343792705721401,0.65638357570629102,"RIMS1"]
["GO:0015682","ferric iron transport",0.18343792705721401,0.65638357570629102,"STEAP3"]
["GO:0015695","organic cation transport",0.18343792705721401,0.65638357570629102,"PRKAB2"]
["GO:0030032","lamellipodium assembly",0.18343792705721401,0.65638357570629102,"CYFIP1"]
["GO:0030261","chromosome condensation",0.18343792705721401,0.65638357570629102,"SMC2"]
["GO:0031572","G2/M transition DNA damage checkpoint",0.18343792705721401,0.65638357570629102,"TAOK2"]
["GO:0032233","positive regulation of actin filament bundle assembly",0.18343792705721401,0.65638357570629102,"LIMK1"]
["GO:0032760","positive regulation of tumor necrosis factor production",0.18343792705721401,0.65638357570629102,"TICAM1"]
["GO:0033572","transferrin transport",0.18343792705721401,0.65638357570629102,"STEAP3"]
["GO:0035094","response to nicotine",0.18343792705721401,0.65638357570629102,"CHRNA7"]
["GO:0042177","negative regulation of protein catabolic process",0.18343792705721401,0.65638357570629102,"FLNA"]
["GO:0042992","negative regulation of transcription factor import into nucleus",0.18343792705721401,0.65638357570629102,"MAPK7"]
["GO:0042993","positive regulation of transcription factor import into nucleus",0.18343792705721401,0.65638357570629102,"FLNA"]
["GO:0045776","negative regulation of blood pressure",0.18343792705721401,0.65638357570629102,"SOD2"]
["GO:0051353","positive regulation of oxidoreductase activity",0.18343792705721401,0.65638357570629102,"ABL1"]
["GO:0060396","growth hormone receptor signaling pathway",0.18343792705721401,0.65638357570629102,"MAPK3"]
["GO:0071378","cellular response to growth hormone stimulus",0.18343792705721401,0.65638357570629102,"MAPK3"]
["GO:0071559","response to transforming growth factor beta stimulus",0.18343792705721401,0.65638357570629102,"MAPK7"]
["GO:0090077","foam cell differentiation",0.18343792705721401,0.65638357570629102,"ABCA1"]
["GO:0090150","establishment of protein localization in membrane",0.18343792705721401,0.65638357570629102,"NRXN1"]
["GO:0032934","sterol binding",0.18343792705721401,0.65638357570629102,"ABCA1"]
["GO:0046966","thyroid hormone receptor binding",0.18343792705721401,0.65638357570629102,"TRIP12"]
["REACT:60","REACT: Activation of Kainate Receptors upon glutamate binding",0.18343792705721401,0.65638357570629102,"PLCB1"]
["REACT:76","REACT: Activation of the pre-replicative complex",0.18343792705721401,0.65638357570629102,"CDK2"]
["REACT:465","REACT: Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity",0.18343792705721401,0.65638357570629102,"CAMK2G"]
["REACT:574","REACT: Intrinsic Pathway for Apoptosis",0.18343792705721401,0.65638357570629102,"MAPK8"]
["REACT:865","REACT: RNA Polymerase I Promoter Opening",0.18343792705721401,0.65638357570629102,"MAPK3"]
["REACT:1147","REACT: Tight junction interactions",0.18343792705721401,0.65638357570629102,"PARD3"]
["REACT:1159","REACT: Trafficking of AMPA receptors",0.18343792705721401,0.65638357570629102,"CAMK2G"]
["NCI:60","NCI:EPHRINBREVPATHWAY",0.18343792705721401,0.65638357570629102,"MAPK8"]
["NCI:142","NCI:NETRIN_PATHWAY",0.18343792705721401,0.65638357570629102,"MAPK3"]
["NCI:150","NCI:P38ALPHABETAPATHWAY",0.18343792705721401,0.65638357570629102,"MAPK11"]
["GO:0009310","amine catabolic process",0.18355484302560199,0.65638357570629102,"CBS;DBT"]
["GO:0016331","morphogenesis of embryonic epithelium",0.18355484302560199,0.65638357570629102,"SKI;ZEB2"]
["GO:0019898","extrinsic to membrane",0.18355484302560199,0.65638357570629102,"SYNJ2;SNX9"]
["GO:0008528","G-protein coupled peptide receptor activity",0.18355484302560199,0.65638357570629102,"GALR1;NTSR2"]
["KEGG:04270","Vascular smooth muscle contraction",0.18355484302560199,0.65638357570629102,"PLCB1;MAPK3"]
["GO:0016032","viral reproduction",0.18399164456616901,0.65752052825584495,"PSMB1;PSMC2;RPL19;TBP;ZSCAN2"]
["GO:0019752","carboxylic acid metabolic process",0.18430899211735099,0.65780473831818298,"CBS;DBT;PRKAB2;MAPK3;PSMB1;PSMC2;SOD2;CYP7B1"]
["GO:0043436","oxoacid metabolic process",0.18430899211735099,0.65780473831818298,"CBS;DBT;PRKAB2;MAPK3;PSMB1;PSMC2;SOD2;CYP7B1"]
["GO:0006812","cation transport",0.18452278456437199,0.65814316196654099,"CACNA1B;CAMK2G;CDK2;CHRNA7;PRKAB2;STEAP3;KCNH8"]
["GO:0070482","response to oxygen levels",0.184725489787501,0.65844162983534404,"CHRNA7;ETS1;SOD2"]
["GO:0006979","response to oxidative stress",0.186414206447129,0.66403309083420303,"ERCC6;ETS1;SOD2"]
["GO:0006629","lipid metabolic process",0.18689644281651499,0.66532247211129902,"ABCA1;PCYT1A;PIK3CB;PRKAB2;MAPK3;SREBF1;SYNJ2;LARGE;CYP7B1;PLCB1"]
["GO:0001653","peptide receptor activity",0.18840111211708899,0.66616930743790703,"GALR1;NTSR2"]
["GO:0001910","regulation of leukocyte mediated cytotoxicity",0.18894064413775799,0.66616930743790703,"PPP3CB"]
["GO:0001974","blood vessel remodeling",0.18894064413775799,0.66616930743790703,"CBS"]
["GO:0002753","cytoplasmic pattern recognition receptor signaling pathway",0.18894064413775799,0.66616930743790703,"IKBKG"]
["GO:0010883","regulation of lipid storage",0.18894064413775799,0.66616930743790703,"ABCA1"]
["GO:0032092","positive regulation of protein binding",0.18894064413775799,0.66616930743790703,"TICAM1"]
["GO:0032755","positive regulation of interleukin-6 production",0.18894064413775799,0.66616930743790703,"TICAM1"]
["GO:0046068","cGMP metabolic process",0.18894064413775799,0.66616930743790703,"CBS"]
["GO:0046470","phosphatidylcholine metabolic process",0.18894064413775799,0.66616930743790703,"PCYT1A"]
["GO:0048538","thymus development",0.18894064413775799,0.66616930743790703,"CRKL"]
["GO:0070423","nucleotide-binding oligomerization domain containing signaling pathway",0.18894064413775799,0.66616930743790703,"IKBKG"]
["GO:0034704","calcium channel complex",0.18894064413775799,0.66616930743790703,"CACNA1B"]
["GO:0005245","voltage-gated calcium channel activity",0.18894064413775799,0.66616930743790703,"CACNA1B"]
["NCI:128","NCI:LIS1PATHWAY",0.18894064413775799,0.66616930743790703,"ABL1"]
["NCI:204","NCI:TCRCALCIUMPATHWAY",0.18894064413775799,0.66616930743790703,"PPP3CB"]
["GO:0007626","locomotory behavior",0.19083102718522499,0.67112348530747801,"PARK2;SOD2"]
["GO:0040029","regulation of gene expression, epigenetic",0.19083102718522499,0.67112348530747801,"BAZ1B;EHMT1"]
["GO:0055001","muscle cell development",0.19083102718522499,0.67112348530747801,"SKI;PLCB1"]
["GO:0016779","nucleotidyltransferase activity",0.19083102718522499,0.67112348530747801,"ABL1;PCYT1A"]
["GO:0030097","hemopoiesis",0.192058178981627,0.67216090004196805,"ETS1;PPP3CB;SOD2;KLF13;SMAP1"]
["GO:0001934","positive regulation of protein phosphorylation",0.19320971079434601,0.67216090004196805,"CSNK1D;MAPK3;TNK2"]
["GO:0001505","regulation of neurotransmitter levels",0.19326523838971599,0.67216090004196805,"PARK2;RIMS1"]
["GO:0008624","induction of apoptosis by extracellular signals",0.19326523838971599,0.67216090004196805,"MAPK8;TICAM1"]
["GO:0006811","ion transport",0.19376068401702301,0.67216090004196805,"ABCA1;CACNA1B;CAMK2G;CDK2;CHRNA7;GRID2;PRKAB2;STEAP3;KCNH8"]
["GO:0002709","regulation of T cell mediated immunity",0.194406623294857,0.67216090004196805,"PPP3CB"]
["GO:0007052","mitotic spindle organization",0.194406623294857,0.67216090004196805,"FLNA"]
["GO:0007062","sister chromatid cohesion",0.194406623294857,0.67216090004196805,"SMC2"]
["GO:0008633","activation of pro-apoptotic gene products",0.194406623294857,0.67216090004196805,"MAPK8"]
["GO:0014902","myotube differentiation",0.194406623294857,0.67216090004196805,"SKI"]
["GO:0032312","regulation of ARF GTPase activity",0.194406623294857,0.67216090004196805,"SMAP1"]
["GO:0032371","regulation of sterol transport",0.194406623294857,0.67216090004196805,"ABCA1"]
["GO:0032374","regulation of cholesterol transport",0.194406623294857,0.67216090004196805,"ABCA1"]
["GO:0032436","positive regulation of proteasomal ubiquitin-dependent protein catabolic process",0.194406623294857,0.67216090004196805,"CSNK1D"]
["GO:0032655","regulation of interleukin-12 production",0.194406623294857,0.67216090004196805,"PLCB1"]
["GO:0035019","somatic stem cell maintenance",0.194406623294857,0.67216090004196805,"SKI"]
["GO:0048742","regulation of skeletal muscle fiber development",0.194406623294857,0.67216090004196805,"PLCB1"]
["GO:0051588","regulation of neurotransmitter transport",0.194406623294857,0.67216090004196805,"PARK2"]
["GO:0060113","inner ear receptor cell differentiation",0.194406623294857,0.67216090004196805,"ATOH1"]
["GO:0071322","cellular response to carbohydrate stimulus",0.194406623294857,0.67216090004196805,"PPP3CB"]
["GO:2001251","negative regulation of chromosome organization",0.194406623294857,0.67216090004196805,"SKI"]
["GO:0005881","cytoplasmic microtubule",0.194406623294857,0.67216090004196805,"SYNJ2"]
["GO:0030532","small nuclear ribonucleoprotein complex",0.194406623294857,0.67216090004196805,"SNRPN"]
["GO:0008060","ARF GTPase activator activity",0.194406623294857,0.67216090004196805,"SMAP1"]
["GO:0019905","syntaxin binding",0.194406623294857,0.67216090004196805,"ABCA1"]
["REACT:1039","REACT: Signaling by Robo receptor",0.194406623294857,0.67216090004196805,"ABL1"]
["REACT:1143","REACT: Thrombin signalling through proteinase activated receptors (PARs)",0.194406623294857,0.67216090004196805,"MAPK3"]
["GO:0001775","cell activation",0.19466917427951999,0.67264826490587504,"FLNA;PIK3CB;PPP3CB;MAPK3;IL1RL1;PLCB1;TICAM1"]
["GO:0006816","calcium ion transport",0.19491844514908499,0.67308916264964902,"CACNA1B;CAMK2G;CHRNA7"]
["GO:0050851","antigen receptor-mediated signaling pathway",0.195703580092915,0.67495773383666302,"PIK3CB;IKBKG"]
["GO:0051427","hormone receptor binding",0.195703580092915,0.67495773383666302,"BAZ1B;TRIP12"]
["GO:0030135","coated vesicle",0.19663100288527899,0.677733774430755,"SREBF1;TNK2;SNX9"]
["GO:0048015","phosphatidylinositol-mediated signaling",0.19814588865129601,0.68210519976289197,"PIK3CB;UBE3A"]
["GO:0048017","inositol lipid-mediated signaling",0.19814588865129601,0.68210519976289197,"PIK3CB;UBE3A"]
["GO:0007584","response to nutrient",0.19834732431927701,0.68237400381482705,"ABCA1;CBS;SOD2"]
["GO:0006082","organic acid metabolic process",0.19877965833924899,0.68343633929939496,"CBS;DBT;PRKAB2;MAPK3;PSMB1;PSMC2;SOD2;CYP7B1"]
["GO:0003044","regulation of systemic arterial blood pressure mediated by a chemical signal",0.199836107504195,0.683669354800992,"SOD2"]
["GO:0050931","pigment cell differentiation",0.199836107504195,0.683669354800992,"SOD2"]
["GO:0051145","smooth muscle cell differentiation",0.199836107504195,0.683669354800992,"SMARCA2"]
["GO:0004712","protein serine/threonine/tyrosine kinase activity",0.199836107504195,0.683669354800992,"TNK2"]
["GO:0016709","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen",0.199836107504195,0.683669354800992,"CYP7B1"]
["REACT:438","REACT: GPVI-mediated activation cascade",0.199836107504195,0.683669354800992,"PIK3CB"]
["REACT:806","REACT: Post NMDA receptor activation events",0.199836107504195,0.683669354800992,"CAMK2G"]
["NCI:178","NCI:RAS_PATHWAY",0.199836107504195,0.683669354800992,"SYNGAP1"]
["GO:0005815","microtubule organizing center",0.20025034141923101,0.68466309563114203,"CDK2;CSNK1D;TSSK2;CEP70;TUBGCP5"]
["GO:0006473","protein acetylation",0.20059200239654501,0.68498454151709198,"MAPK3;KAT2B"]
["GO:0009743","response to carbohydrate stimulus",0.20059200239654501,0.68498454151709198,"PPP3CB;PLCB1"]
["GO:0007507","heart development",0.20142406618744299,0.68740156332445201,"CRKL;PPP3CB;SOD2;BAZ1B"]
["GO:0050878","regulation of body fluid levels",0.20316891880205601,0.69274734139746796,"ABL1;CDK2;FLNA;PIK3CB;MAPK3;RAB5A"]
["GO:0001655","urogenital system development",0.20351827647025,0.69274734139746796,"ESR2;UBE3A;CYP7B1"]
["GO:0000038","very long-chain fatty acid metabolic process",0.205229338149678,0.69274734139746796,"MAPK3"]
["GO:0001678","cellular glucose homeostasis",0.205229338149678,0.69274734139746796,"PPP3CB"]
["GO:0007257","activation of JUN kinase activity",0.205229338149678,0.69274734139746796,"ERCC6"]
["GO:0007632","visual behavior",0.205229338149678,0.69274734139746796,"SYNGAP1"]
["GO:0015914","phospholipid transport",0.205229338149678,0.69274734139746796,"ABCA1"]
["GO:0030890","positive regulation of B cell proliferation",0.205229338149678,0.69274734139746796,"TICAM1"]
["GO:0032611","interleukin-1 beta production",0.205229338149678,0.69274734139746796,"ABCA1"]
["GO:0032615","interleukin-12 production",0.205229338149678,0.69274734139746796,"PLCB1"]
["GO:0034109","homotypic cell-cell adhesion",0.205229338149678,0.69274734139746796,"PIK3CB"]
["GO:0043488","regulation of mRNA stability",0.205229338149678,0.69274734139746796,"SYNCRIP"]
["GO:0003727","single-stranded RNA binding",0.205229338149678,0.69274734139746796,"MSI2"]
["GO:0035064","methylated histone residue binding",0.205229338149678,0.69274734139746796,"UHRF1"]
["NCI:20","NCI:ATM_PATHWAY",0.205229338149678,0.69274734139746796,"ABL1"]
["NCI:55","NCI:EPHA_FWDPATHWAY",0.205229338149678,0.69274734139746796,"CRKL"]
["NCI:93","NCI:HIF2PATHWAY",0.205229338149678,0.69274734139746796,"ETS1"]
["GO:0042176","regulation of protein catabolic process",0.205495008538186,0.69274734139746796,"CSNK1D;FLNA"]
["GO:0000976","transcription regulatory region sequence-specific DNA binding",0.205495008538186,0.69274734139746796,"ESR2;UHRF1"]
["REACT:552","REACT: Integration of energy metabolism",0.205495008538186,0.69274734139746796,"PLCB1;PRKAB2"]
["GO:0050796","regulation of insulin secretion",0.20795158730614199,0.70060181545528499,"PPP3CB;RFX3"]
["GO:0042180","cellular ketone metabolic process",0.20838992259976899,0.70165127925862503,"CBS;DBT;PRKAB2;MAPK3;PSMB1;PSMC2;SOD2;CYP7B1"]
["GO:0006164","purine nucleotide biosynthetic process",0.208720969535412,0.70178603761854597,"ABCA1;FLNA;GALR1"]
["GO:0051223","regulation of protein transport",0.208720969535412,0.70178603761854597,"FLNA;MAPK7;IL1RL1"]
["GO:0006576","cellular biogenic amine metabolic process",0.21041134396740199,0.70178603761854597,"PARK2;PCYT1A"]
["GO:0010038","response to metal ion",0.21046198001275099,0.70178603761854597,"MAPK8;SOD2;CUTA"]
["GO:0009755","hormone-mediated signaling pathway",0.210586555033765,0.70178603761854597,"ESR2"]
["GO:0032024","positive regulation of insulin secretion",0.210586555033765,0.70178603761854597,"PPP3CB"]
["GO:0042743","hydrogen peroxide metabolic process",0.210586555033765,0.70178603761854597,"SOD2"]
["GO:0043954","cellular component maintenance",0.210586555033765,0.70178603761854597,"ERCC6"]
["GO:0050807","regulation of synapse organization",0.210586555033765,0.70178603761854597,"NRXN1"]
["GO:0070830","tight junction assembly",0.210586555033765,0.70178603761854597,"PARD3"]
["GO:0019825","oxygen binding",0.210586555033765,0.70178603761854597,"SOD2"]
["REACT:882","REACT: RNA Polymerase III Transcription Initiation",0.210586555033765,0.70178603761854597,"TBP"]
["REACT:1011","REACT: Signal transduction by L1",0.210586555033765,0.70178603761854597,"MAPK3"]
["KEGG:00270","Cysteine and methionine metabolism",0.210586555033765,0.70178603761854597,"CBS"]
["KEGG:05020","Prion diseases",0.210586555033765,0.70178603761854597,"MAPK3"]
["NCI:84","NCI:GMCSF_PATHWAY",0.210586555033765,0.70178603761854597,"MAPK3"]
["NCI:94","NCI:HIVNEFPATHWAY",0.210586555033765,0.70178603761854597,"MAPK8"]
["GO:0030001","metal ion transport",0.21268450679394801,0.70812968582748803,"CACNA1B;CAMK2G;CDK2;CHRNA7;STEAP3;KCNH8"]
["GO:0071214","cellular response to abiotic stimulus",0.21287412645175599,0.70812968582748803,"MAPK3;MAPK8"]
["GO:0020037","heme binding",0.21287412645175599,0.70812968582748803,"CBS;CYP7B1"]
["GO:0016874","ligase activity",0.21336300154493701,0.70932940177078696,"PARK2;UBE3A;TRIP12;UHRF1;UBE2W"]
["GO:0030424","axon",0.213953820254559,0.71010882046188195,"SYNJ2;DLGAP2;NRXN1"]
["GO:0007205","activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway",0.21590799638772301,0.71010882046188195,"PARD3"]
["GO:0009948","anterior/posterior axis specification",0.21590799638772301,0.71010882046188195,"SKI"]
["GO:0031341","regulation of cell killing",0.21590799638772301,0.71010882046188195,"PPP3CB"]
["GO:0033344","cholesterol efflux",0.21590799638772301,0.71010882046188195,"ABCA1"]
["GO:0035914","skeletal muscle cell differentiation",0.21590799638772301,0.71010882046188195,"SKI"]
["GO:0042490","mechanoreceptor differentiation",0.21590799638772301,0.71010882046188195,"ATOH1"]
["GO:0042752","regulation of circadian rhythm",0.21590799638772301,0.71010882046188195,"CSNK1D"]
["GO:0043487","regulation of RNA stability",0.21590799638772301,0.71010882046188195,"SYNCRIP"]
["GO:0046320","regulation of fatty acid oxidation",0.21590799638772301,0.71010882046188195,"PRKAB2"]
["GO:0060350","endochondral bone morphogenesis",0.21590799638772301,0.71010882046188195,"CBS"]
["GO:2001252","positive regulation of chromosome organization",0.21590799638772301,0.71010882046188195,"MAPK3"]
["GO:0001047","core promoter binding",0.21590799638772301,0.71010882046188195,"ESR2"]
["GO:0003725","double-stranded RNA binding",0.21590799638772301,0.71010882046188195,"STAU2"]
["GO:0048306","calcium-dependent protein binding",0.21590799638772301,0.71010882046188195,"NRXN1"]
["REACT:712","REACT: Neurotransmitter Release Cycle",0.21590799638772301,0.71010882046188195,"RIMS1"]
["KEGG:05143","African trypanosomiasis",0.21590799638772301,0.71010882046188195,"PLCB1"]
["NCI:56","NCI:EPHBFWDPATHWAY",0.21590799638772301,0.71010882046188195,"MAPK3"]
["GO:0045934","negative regulation of nucleobase-containing compound metabolic process",0.21639014825366801,0.71127171725448202,"ESR2;FLNA;GALR1;RFX3;SKI;SMARCA2;PLCB1;EHMT1"]
["GO:0005794","Golgi apparatus",0.217338268766474,0.71381208292602505,"ABCA1;CSNK1D;FLNA;PARK2;MAPK3;SREBF1;LARGE;ARHGAP32;RER1;SNX9"]
["GO:0048608","reproductive structure development",0.21745836665568199,0.71381208292602505,"ESR2;UBE3A;CYP7B1"]
["GO:0006836","neurotransmitter transport",0.21780816991669,0.71381208292602505,"PARK2;RIMS1"]
["GO:0030308","negative regulation of cell growth",0.21780816991669,0.71381208292602505,"ESR2;SMARCA2"]
["GO:0046034","ATP metabolic process",0.21780816991669,0.71381208292602505,"PSMC2;CHD1L"]
["GO:0017038","protein import",0.21921526056864801,0.71683927862583696,"FLNA;MAPK3;MAPK7"]
["GO:0002429","immune response-activating cell surface receptor signaling pathway",0.220279136011371,0.71683927862583696,"PIK3CB;IKBKG"]
["GO:0008654","phospholipid biosynthetic process",0.220279136011371,0.71683927862583696,"PCYT1A;PIK3CB"]
["GO:0019933","cAMP-mediated signaling",0.220279136011371,0.71683927862583696,"FLNA;GALR1"]
["GO:0046822","regulation of nucleocytoplasmic transport",0.220279136011371,0.71683927862583696,"FLNA;MAPK7"]
["GO:0001709","cell fate determination",0.221193898881833,0.71683927862583696,"ATOH1"]
["GO:0006305","DNA alkylation",0.221193898881833,0.71683927862583696,"EHMT1"]
["GO:0006306","DNA methylation",0.221193898881833,0.71683927862583696,"EHMT1"]
["GO:0007030","Golgi organization",0.221193898881833,0.71683927862583696,"MAPK3"]
["GO:0014823","response to activity",0.221193898881833,0.71683927862583696,"SOD2"]
["GO:0015909","long-chain fatty acid transport",0.221193898881833,0.71683927862583696,"PRKAB2"]
["GO:0021983","pituitary gland development",0.221193898881833,0.71683927862583696,"ETS1"]
["GO:0048041","focal adhesion assembly",0.221193898881833,0.71683927862583696,"TAOK2"]
["GO:0051937","catecholamine transport",0.221193898881833,0.71683927862583696,"PARK2"]
["GO:0005657","replication fork",0.221193898881833,0.71683927862583696,"BAZ1B"]
["REACT:43","REACT: Activation of ATR in response to replication stress",0.221193898881833,0.71683927862583696,"CDK2"]
["REACT:63","REACT: Activation of NMDA receptor upon glutamate binding and postsynaptic events",0.221193898881833,0.71683927862583696,"CAMK2G"]
["REACT:758","REACT: PI3K/AKT activation",0.221193898881833,0.71683927862583696,"PIK3CB"]
["KEGG:00260","Glycine, serine and threonine metabolism",0.221193898881833,0.71683927862583696,"CBS"]
["GO:0007565","female pregnancy",0.22275253812218199,0.72062400052158504,"CBS;ETS1"]
["GO:0033157","regulation of intracellular protein transport",0.22275253812218199,0.72062400052158504,"FLNA;MAPK7"]
["KEGG:04530","Tight junction",0.22275253812218199,0.72062400052158504,"PARD3;CDK4"]
["GO:0051172","negative regulation of nitrogen compound metabolic process",0.22360101866661899,0.72294613399400098,"ESR2;FLNA;GALR1;RFX3;SKI;SMARCA2;PLCB1;EHMT1"]
["GO:0016477","cell migration",0.22442477272943101,0.72451761765162204,"ATOH1;ESR2;ETS1;PIK3CB;TAOK2;ZEB2;PLCB1"]
["GO:0042327","positive regulation of phosphorylation",0.22450373832121501,0.72451761765162204,"CSNK1D;MAPK3;TNK2"]
["GO:0045927","positive regulation of growth",0.225228233327947,0.72451761765162204,"LIMK1;PLCB1"]
["KEGG:04514","Cell adhesion molecules (CAMs)",0.225228233327947,0.72451761765162204,"NRXN3;NRXN1"]
["GO:0016788","hydrolase activity, acting on ester bonds",0.22541120940155601,0.72451761765162204,"CAMK2G;PPP3CB;PTPRD;RNASE1;RNASE6;SYNJ2;PLCB1"]
["GO:0065003","macromolecular complex assembly",0.22632851321383299,0.72451761765162204,"ABCA1;MAX;MAPK3;SKI;SOD2;RIMS1;SNX9;PARD3"]
["GO:0001755","neural crest cell migration",0.226444497635512,0.72451761765162204,"ZEB2"]
["GO:0006637","acyl-CoA metabolic process",0.226444497635512,0.72451761765162204,"DBT"]
["GO:0014068","positive regulation of phosphatidylinositol 3-kinase cascade",0.226444497635512,0.72451761765162204,"UBE3A"]
["GO:0032612","interleukin-1 production",0.226444497635512,0.72451761765162204,"ABCA1"]
["GO:0035383","thioester metabolic process",0.226444497635512,0.72451761765162204,"DBT"]
["GO:0050806","positive regulation of synaptic transmission",0.226444497635512,0.72451761765162204,"NRXN1"]
["GO:0004435","phosphatidylinositol phospholipase C activity",0.226444497635512,0.72451761765162204,"PLCB1"]
["GO:0008375","acetylglucosaminyltransferase activity",0.226444497635512,0.72451761765162204,"LARGE"]
["REACT:263","REACT: Cyclin D associated events in G1",0.226444497635512,0.72451761765162204,"CDK4"]
["REACT:374","REACT: FRS2-mediated cascade",0.226444497635512,0.72451761765162204,"MAPK3"]
["REACT:419","REACT: G1 Phase",0.226444497635512,0.72451761765162204,"CDK4"]
["KEGG:05340","Primary immunodeficiency",0.226444497635512,0.72451761765162204,"IKBKG"]
["GO:0016071","mRNA metabolic process",0.228886091935217,0.72939286573129603,"MAPK11;PSMB1;PSMC2;RPL19;WTAP;SYNCRIP"]
["GO:0051924","regulation of calcium ion transport",0.23018594021049699,0.72939286573129603,"CACNA1B;CAMK2G"]
["GO:0090276","regulation of peptide hormone secretion",0.23018594021049699,0.72939286573129603,"PPP3CB;RFX3"]
["REACT:505","REACT: Host Interactions of HIV factors",0.23018594021049699,0.72939286573129603,"PSMB1;PSMC2"]
["GO:0072522","purine-containing compound biosynthetic process",0.231594448569375,0.72939286573129603,"ABCA1;FLNA;GALR1"]
["GO:0090066","regulation of anatomical structure size",0.231594448569375,0.72939286573129603,"CBS;LIMK1;SOD2"]
["GO:0002456","T cell mediated immunity",0.23166002622738399,0.72939286573129603,"PPP3CB"]
["GO:0006284","base-excision repair",0.23166002622738399,0.72939286573129603,"ERCC6"]
["GO:0010043","response to zinc ion",0.23166002622738399,0.72939286573129603,"SOD2"]
["GO:0031576","G2/M transition checkpoint",0.23166002622738399,0.72939286573129603,"TAOK2"]
["GO:0038032","termination of G-protein coupled receptor signaling pathway",0.23166002622738399,0.72939286573129603,"SNX14"]
["GO:0043500","muscle adaptation",0.23166002622738399,0.72939286573129603,"CAMK2G"]
["GO:0048146","positive regulation of fibroblast proliferation",0.23166002622738399,0.72939286573129603,"CDK4"]
["GO:0048168","regulation of neuronal synaptic plasticity",0.23166002622738399,0.72939286573129603,"SYNGAP1"]
["GO:0072659","protein localization in plasma membrane",0.23166002622738399,0.72939286573129603,"NRXN1"]
["GO:0005876","spindle microtubule",0.23166002622738399,0.72939286573129603,"CSNK1D"]
["GO:0000149","SNARE binding",0.23166002622738399,0.72939286573129603,"ABCA1"]
["GO:0018024","histone-lysine N-methyltransferase activity",0.23166002622738399,0.72939286573129603,"EHMT1"]
["REACT:486","REACT: HIV-1 Transcription Initiation",0.23166002622738399,0.72939286573129603,"TBP"]
["REACT:579","REACT: Iron uptake and transport",0.23166002622738399,0.72939286573129603,"STEAP3"]
["REACT:870","REACT: RNA Polymerase II HIV-1 Promoter Escape",0.23166002622738399,0.72939286573129603,"TBP"]
["REACT:872","REACT: RNA Polymerase II Promoter Escape",0.23166002622738399,0.72939286573129603,"TBP"]
["REACT:875","REACT: RNA Polymerase II Transcription Initiation",0.23166002622738399,0.72939286573129603,"TBP"]
["REACT:876","REACT: RNA Polymerase II Transcription Initiation And Promoter Clearance",0.23166002622738399,0.72939286573129603,"TBP"]
["REACT:877","REACT: RNA Polymerase II Transcription Pre-Initiation And Promoter Opening",0.23166002622738399,0.72939286573129603,"TBP"]
["NCI:21","NCI:ATR_PATHWAY",0.23166002622738399,0.72939286573129603,"CDK2"]
["NCI:23","NCI:AURORA_B_PATHWAY",0.23166002622738399,0.72939286573129603,"SMC2"]
["NCI:85","NCI:HDAC_CLASSIII_PATHWAY",0.23166002622738399,0.72939286573129603,"KAT2B"]
["GO:0007160","cell-matrix adhesion",0.23266767486475701,0.72965849056226495,"PIK3CB;TAOK2"]
["GO:0043543","protein acylation",0.23266767486475701,0.72965849056226495,"MAPK3;KAT2B"]
["GO:0051222","positive regulation of protein transport",0.23266767486475701,0.72965849056226495,"FLNA;IL1RL1"]
["GO:0015276","ligand-gated ion channel activity",0.23266767486475701,0.72965849056226495,"CHRNA7;GRID2"]
["GO:0022834","ligand-gated channel activity",0.23266767486475701,0.72965849056226495,"CHRNA7;GRID2"]
["GO:0043176","amine binding",0.23266767486475701,0.72965849056226495,"CBS;CHRNA7"]
["GO:0046906","tetrapyrrole binding",0.23266767486475701,0.72965849056226495,"CBS;CYP7B1"]
["GO:0002791","regulation of peptide secretion",0.235151148535231,0.73619476723084298,"PPP3CB;RFX3"]
["GO:0007519","skeletal muscle tissue development",0.235151148535231,0.73619476723084298,"SKI;PLCB1"]
["GO:0090087","regulation of peptide transport",0.235151148535231,0.73619476723084298,"PPP3CB;RFX3"]
["GO:0001676","long-chain fatty acid metabolic process",0.23684071670527601,0.73689698808413195,"MAPK3"]
["GO:0007098","centrosome cycle",0.23684071670527601,0.73689698808413195,"CDK2"]
["GO:0046677","response to antibiotic",0.23684071670527601,0.73689698808413195,"ETS1"]
["GO:0005913","cell-cell adherens junction",0.23684071670527601,0.73689698808413195,"PARD3"]
["GO:0045335","phagocytic vesicle",0.23684071670527601,0.73689698808413195,"ABCA1"]
["GO:0016836","hydro-lyase activity",0.23684071670527601,0.73689698808413195,"CBS"]
["REACT:568","REACT: Interleukin-1 signaling",0.23684071670527601,0.73689698808413195,"IKBKG"]
["REACT:701","REACT: Negative regulation of FGFR signaling",0.23684071670527601,0.73689698808413195,"MAPK3"]
["REACT:879","REACT: RNA Polymerase III Abortive And Retractive Initiation",0.23684071670527601,0.73689698808413195,"TBP"]
["REACT:881","REACT: RNA Polymerase III Transcription",0.23684071670527601,0.73689698808413195,"TBP"]
["NCI:203","NCI:TCPTP_PATHWAY",0.23684071670527601,0.73689698808413195,"PIK3CB"]
["GO:0002768","immune response-regulating cell surface receptor signaling pathway",0.23763622701950499,0.73854135273702504,"PIK3CB;IKBKG"]
["GO:0006469","negative regulation of protein kinase activity",0.23763622701950499,0.73854135273702504,"ABL1;KAT2B"]
["GO:0010562","positive regulation of phosphorus metabolic process",0.24051612663244501,0.74660957912211701,"CSNK1D;MAPK3;TNK2"]
["GO:0045937","positive regulation of phosphate metabolic process",0.24051612663244501,0.74660957912211701,"CSNK1D;MAPK3;TNK2"]
["GO:0000096","sulfur amino acid metabolic process",0.24198679959616001,0.74660957912211701,"CBS"]
["GO:0030512","negative regulation of transforming growth factor beta receptor signaling pathway",0.24198679959616001,0.74660957912211701,"SKI"]
["GO:0030516","regulation of axon extension",0.24198679959616001,0.74660957912211701,"LIMK1"]
["GO:0042311","vasodilation",0.24198679959616001,0.74660957912211701,"SOD2"]
["GO:0051971","positive regulation of transmission of nerve impulse",0.24198679959616001,0.74660957912211701,"NRXN1"]
["GO:0060416","response to growth hormone stimulus",0.24198679959616001,0.74660957912211701,"MAPK3"]
["GO:0004860","protein kinase inhibitor activity",0.24198679959616001,0.74660957912211701,"KAT2B"]
["GO:0016278","lysine N-methyltransferase activity",0.24198679959616001,0.74660957912211701,"EHMT1"]
["GO:0016279","protein-lysine N-methyltransferase activity",0.24198679959616001,0.74660957912211701,"EHMT1"]
["REACT:820","REACT: Pre-NOTCH Transcription and Translation",0.24198679959616001,0.74660957912211701,"KAT2B"]
["REACT:1169","REACT: Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer",0.24198679959616001,0.74660957912211701,"SKI"]
["GO:0005681","spliceosomal complex",0.242610670072057,0.74790431028930904,"SNRPN;SYNCRIP"]
["GO:0071345","cellular response to cytokine stimulus",0.24267683242395299,0.74790431028930904,"CAMK2G;MAPK3;IL1RL1;PLCB1"]
["GO:0051259","protein oligomerization",0.24410151467677699,0.75187615767924798,"SKI;SOD2;SNX9"]
["GO:0005770","late endosome",0.245099774638872,0.753555084709712,"MAPK3;STEAP3"]
["GO:0006584","catecholamine metabolic process",0.24709850391601901,0.753555084709712,"PARK2"]
["GO:0006749","glutathione metabolic process",0.24709850391601901,0.753555084709712,"SOD2"]
["GO:0006997","nucleus organization",0.24709850391601901,0.753555084709712,"ETS1"]
["GO:0008206","bile acid metabolic process",0.24709850391601901,0.753555084709712,"CYP7B1"]
["GO:0009712","catechol-containing compound metabolic process",0.24709850391601901,0.753555084709712,"PARK2"]
["GO:0023021","termination of signal transduction",0.24709850391601901,0.753555084709712,"SNX14"]
["GO:0034311","diol metabolic process",0.24709850391601901,0.753555084709712,"PARK2"]
["GO:0034968","histone lysine methylation",0.24709850391601901,0.753555084709712,"EHMT1"]
["GO:0042308","negative regulation of protein import into nucleus",0.24709850391601901,0.753555084709712,"MAPK7"]
["GO:0043297","apical junction assembly",0.24709850391601901,0.753555084709712,"PARD3"]
["GO:0045055","regulated secretory pathway",0.24709850391601901,0.753555084709712,"RIMS1"]
["GO:0051925","regulation of calcium ion transport via voltage-gated calcium channel activity",0.24709850391601901,0.753555084709712,"CACNA1B"]
["GO:0060491","regulation of cell projection assembly",0.24709850391601901,0.753555084709712,"RAB5A"]
["GO:0070301","cellular response to hydrogen peroxide",0.24709850391601901,0.753555084709712,"ETS1"]
["GO:0090277","positive regulation of peptide hormone secretion",0.24709850391601901,0.753555084709712,"PPP3CB"]
["GO:0017137","Rab GTPase binding",0.24709850391601901,0.753555084709712,"RIMS1"]
["NCI:32","NCI:BMPPATHWAY",0.24709850391601901,0.753555084709712,"SKI"]
["GO:0007187","G-protein signaling, coupled to cyclic nucleotide second messenger",0.24758996398429101,0.75463784063972295,"FLNA;GALR1"]
["GO:0000279","M phase",0.24917059146560699,0.75903728633686096,"CDK2;CSNK1D;FLNA;SMC2;PLCB1"]
["GO:0001503","ossification",0.24949614653570801,0.75961072241911698,"CBS;MAPK8;SKI"]
["GO:0007126","meiosis",0.250081112212447,0.76055454247347798,"CDK2;PLCB1"]
["GO:0051327","M phase of meiotic cell cycle",0.250081112212447,0.76055454247347798,"CDK2;PLCB1"]
["GO:0002275","myeloid cell activation involved in immune response",0.25217605717966401,0.76273261253028901,"TICAM1"]
["GO:0002793","positive regulation of peptide secretion",0.25217605717966401,0.76273261253028901,"PPP3CB"]
["GO:0018107","peptidyl-threonine phosphorylation",0.25217605717966401,0.76273261253028901,"MAPK8"]
["GO:0046847","filopodium assembly",0.25217605717966401,0.76273261253028901,"RAB5A"]
["GO:0046889","positive regulation of lipid biosynthetic process",0.25217605717966401,0.76273261253028901,"SREBF1"]
["GO:0005504","fatty acid binding",0.25217605717966401,0.76273261253028901,"DBI"]
["GO:0019210","kinase inhibitor activity",0.25217605717966401,0.76273261253028901,"KAT2B"]
["REACT:424","REACT: G2/M Checkpoints",0.25217605717966401,0.76273261253028901,"CDK2"]
["REACT:765","REACT: PLC beta mediated events",0.25217605717966401,0.76273261253028901,"PLCB1"]
["REACT:1237","REACT: Voltage gated Potassium channels",0.25217605717966401,0.76273261253028901,"KCNH8"]
["GO:0006470","protein dephosphorylation",0.25257309504086001,0.76351604468089396,"PPP3CB;PTPRD"]
["GO:0016053","organic acid biosynthetic process",0.25490934985153801,0.76847875933444698,"CBS;PRKAB2;CYP7B1"]
["GO:0016311","dephosphorylation",0.25490934985153801,0.76847875933444698,"PPP3CB;PTPRD;SYNJ2"]
["GO:0046394","carboxylic acid biosynthetic process",0.25490934985153801,0.76847875933444698,"CBS;PRKAB2;CYP7B1"]
["GO:0070838","divalent metal ion transport",0.25490934985153801,0.76847875933444698,"CACNA1B;CAMK2G;CHRNA7"]
["GO:0071845","cellular component disassembly at cellular level",0.25490934985153801,0.76847875933444698,"ETS1;RPL19;BAZ1B"]
["GO:0051321","meiotic cell cycle",0.25506578978477301,0.76853156268483802,"CDK2;PLCB1"]
["GO:0002088","lens development in camera-type eye",0.25721968541047202,0.76957236327243495,"SKI"]
["GO:0006283","transcription-coupled nucleotide-excision repair",0.25721968541047202,0.76957236327243495,"ERCC6"]
["GO:0031646","positive regulation of neurological system process",0.25721968541047202,0.76957236327243495,"NRXN1"]
["GO:0043966","histone H3 acetylation",0.25721968541047202,0.76957236327243495,"KAT2B"]
["GO:0048489","synaptic vesicle transport",0.25721968541047202,0.76957236327243495,"RIMS1"]
["GO:0048641","regulation of skeletal muscle tissue development",0.25721968541047202,0.76957236327243495,"PLCB1"]
["GO:0000781","chromosome, telomeric region",0.25721968541047202,0.76957236327243495,"CDK2"]
["GO:0051219","phosphoprotein binding",0.25721968541047202,0.76957236327243495,"MAPK3"]
["REACT:417","REACT: G-protein mediated events",0.25721968541047202,0.76957236327243495,"PLCB1"]
["REACT:1165","REACT: Transcription-coupled NER (TC-NER)",0.25721968541047202,0.76957236327243495,"ERCC6"]
["KEGG:00280","Valine, leucine and isoleucine degradation",0.25721968541047202,0.76957236327243495,"DBT"]
["KEGG:02010","ABC transporters",0.25721968541047202,0.76957236327243495,"ABCA1"]
["KEGG:04973","Carbohydrate digestion and absorption",0.25721968541047202,0.76957236327243495,"PIK3CB"]
["GO:0060538","skeletal muscle organ development",0.25755907534163602,0.77017124583239405,"SKI;PLCB1"]
["GO:0033673","negative regulation of kinase activity",0.26005283217571301,0.776788481423351,"ABL1;KAT2B"]
["GO:0043523","regulation of neuron apoptosis",0.26005283217571301,0.776788481423351,"GRID2;SOD2"]
["GO:0022411","cellular component disassembly",0.262153371949717,0.77755369632529303,"ETS1;RPL19;BAZ1B"]
["GO:0072511","divalent inorganic cation transport",0.262153371949717,0.77755369632529303,"CACNA1B;CAMK2G;CHRNA7"]
["GO:0008306","associative learning",0.26222961315007598,0.77755369632529303,"SYNGAP1"]
["GO:0014066","regulation of phosphatidylinositol 3-kinase cascade",0.26222961315007598,0.77755369632529303,"UBE3A"]
["GO:0021766","hippocampus development",0.26222961315007598,0.77755369632529303,"ZEB2"]
["GO:0045727","positive regulation of translation",0.26222961315007598,0.77755369632529303,"MAPK3"]
["GO:0061387","regulation of extent of cell growth",0.26222961315007598,0.77755369632529303,"LIMK1"]
["GO:0090263","positive regulation of canonical Wnt receptor signaling pathway",0.26222961315007598,0.77755369632529303,"CSNK1D"]
["GO:0097006","regulation of plasma lipoprotein particle levels",0.26222961315007598,0.77755369632529303,"ABCA1"]
["GO:0002039","p53 binding",0.26222961315007598,0.77755369632529303,"EHMT1"]
["KEGG:03022","Basal transcription factors",0.26222961315007598,0.77755369632529303,"TBP"]
["NCI:111","NCI:IL6_7PATHWAY",0.26222961315007598,0.77755369632529303,"MAPK11"]
["NCI:185","NCI:RHOA_REG_PATHWAY",0.26222961315007598,0.77755369632529303,"ARHGDIA"]
["GO:0019882","antigen processing and presentation",0.26254694230282799,0.77755369632529303,"PSMB1;PSMC2"]
["GO:0051216","cartilage development",0.26254694230282799,0.77755369632529303,"CBS;MAPK3"]
["GO:0006952","defense response",0.26255790034990001,0.77755369632529303,"CAMK2G;MAPK3;MAPK7;MAPK8;MAPK11;RNASE6;IKBKG;IL1RL1;TICAM1"]
["GO:0006916","anti-apoptosis",0.26396874637702999,0.78131359280777501,"ARHGDIA;ETS1;SOD2"]
["GO:0046578","regulation of Ras protein signal transduction",0.26578576492342598,0.78401704957006202,"SYNGAP1;SMAP1;RALGAPA1"]
["REACT:138","REACT: Axon guidance",0.26578576492342598,0.78401704957006202,"ABL1;LIMK1;MAPK3"]
["GO:0001909","leukocyte mediated cytotoxicity",0.26720606346798198,0.78401704957006202,"PPP3CB"]
["GO:0018210","peptidyl-threonine modification",0.26720606346798198,0.78401704957006202,"MAPK8"]
["GO:0019432","triglyceride biosynthetic process",0.26720606346798198,0.78401704957006202,"SREBF1"]
["GO:0031018","endocrine pancreas development",0.26720606346798198,0.78401704957006202,"RFX3"]
["GO:0042439","ethanolamine-containing compound metabolic process",0.26720606346798198,0.78401704957006202,"PCYT1A"]
["GO:0048066","developmental pigmentation",0.26720606346798198,0.78401704957006202,"SOD2"]
["GO:0050715","positive regulation of cytokine secretion",0.26720606346798198,0.78401704957006202,"IL1RL1"]
["GO:0071300","cellular response to retinoic acid",0.26720606346798198,0.78401704957006202,"ABCA1"]
["KEGG:03420","Nucleotide excision repair",0.26720606346798198,0.78401704957006202,"ERCC6"]
["KEGG:04975","Fat digestion and absorption",0.26720606346798198,0.78401704957006202,"ABCA1"]
["NCI:164","NCI:PI3KCIPATHWAY",0.26720606346798198,0.78401704957006202,"PIK3CB"]
["NCI:172","NCI:PS1PATHWAY",0.26720606346798198,0.78401704957006202,"MAPK3"]
["NCI:197","NCI:SYNDECAN_1_PATHWAY",0.26720606346798198,0.78401704957006202,"MAPK3"]
["NCI:213","NCI:TNFPATHWAY",0.26720606346798198,0.78401704957006202,"IKBKG"]
["GO:0010639","negative regulation of organelle organization",0.267535758166631,0.78401704957006202,"PARK2;SKI"]
["GO:0050727","regulation of inflammatory response",0.267535758166631,0.78401704957006202,"MAPK7;IL1RL1"]
["GO:0003006","developmental process involved in reproduction",0.267716595559987,0.78401704957006202,"ESR2;UBE3A;CYP7B1;TSSK2"]
["GO:0055080","cation homeostasis",0.267716595559987,0.78401704957006202,"CHRNA7;PIK3CB;SOD2;STEAP3"]
["GO:0008202","steroid metabolic process",0.269424529504528,0.78860132127992,"ABCA1;SREBF1;CYP7B1"]
["GO:0002698","negative regulation of immune effector process",0.27214925797112899,0.79155083864158104,"PPP3CB"]
["GO:0006687","glycosphingolipid metabolic process",0.27214925797112899,0.79155083864158104,"LARGE"]
["GO:0007193","inhibition of adenylate cyclase activity by G-protein signaling pathway",0.27214925797112899,0.79155083864158104,"FLNA"]
["GO:0030888","regulation of B cell proliferation",0.27214925797112899,0.79155083864158104,"TICAM1"]
["GO:0046823","negative regulation of nucleocytoplasmic transport",0.27214925797112899,0.79155083864158104,"MAPK7"]
["GO:0051289","protein homotetramerization",0.27214925797112899,0.79155083864158104,"SOD2"]
["GO:0071299","cellular response to vitamin A",0.27214925797112899,0.79155083864158104,"ABCA1"]
["GO:0050839","cell adhesion molecule binding",0.27214925797112899,0.79155083864158104,"NRXN1"]
["GO:0051087","chaperone binding",0.27214925797112899,0.79155083864158104,"PARK2"]
["REACT:689","REACT: NOTCH1 Intracellular Domain Regulates Transcription",0.27214925797112899,0.79155083864158104,"KAT2B"]
["REACT:690","REACT: NRAGE signals death through JNK",0.27214925797112899,0.79155083864158104,"MAPK8"]
["KEGG:04330","Notch signaling pathway",0.27214925797112899,0.79155083864158104,"KAT2B"]
["GO:0007155","cell adhesion",0.274450218146022,0.79661782422644101,"ABL1;ARHGDIA;LSAMP;PIK3CB;MAPK7;TAOK2;NRXN3;NRXN1"]
["GO:0022610","biological adhesion",0.274450218146022,0.79661782422644101,"ABL1;ARHGDIA;LSAMP;PIK3CB;MAPK7;TAOK2;NRXN3;NRXN1"]
["GO:0031327","negative regulation of cellular biosynthetic process",0.274450218146022,0.79661782422644101,"ESR2;FLNA;GALR1;RFX3;SKI;SMARCA2;PLCB1;EHMT1"]
["GO:0000775","chromosome, centromeric region",0.27501876960194499,0.79661782422644101,"KAT2B;BAZ1B"]
["GO:0048729","tissue morphogenesis",0.27517450255656301,0.79661782422644101,"ESR2;SKI;CYP7B1;ZEB2"]
["GO:0000070","mitotic sister chromatid segregation",0.27705941681339002,0.79661782422644101,"SMC2"]
["GO:0006826","iron ion transport",0.27705941681339002,0.79661782422644101,"STEAP3"]
["GO:0007189","activation of adenylate cyclase activity by G-protein signaling pathway",0.27705941681339002,0.79661782422644101,"GALR1"]
["GO:0010578","regulation of adenylate cyclase activity involved in G-protein signaling pathway",0.27705941681339002,0.79661782422644101,"GALR1"]
["GO:0010579","positive regulation of adenylate cyclase activity by G-protein signaling pathway",0.27705941681339002,0.79661782422644101,"GALR1"]
["GO:0019915","lipid storage",0.27705941681339002,0.79661782422644101,"ABCA1"]
["GO:0032012","regulation of ARF protein signal transduction",0.27705941681339002,0.79661782422644101,"SMAP1"]
["GO:0032434","regulation of proteasomal ubiquitin-dependent protein catabolic process",0.27705941681339002,0.79661782422644101,"CSNK1D"]
["GO:0035872","nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway",0.27705941681339002,0.79661782422644101,"IKBKG"]
["GO:0051153","regulation of striated muscle cell differentiation",0.27705941681339002,0.79661782422644101,"PLCB1"]
["GO:2000377","regulation of reactive oxygen species metabolic process",0.27705941681339002,0.79661782422644101,"PARK2"]
["GO:0008287","protein serine/threonine phosphatase complex",0.27705941681339002,0.79661782422644101,"PPP3CB"]
["GO:0004879","ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity",0.27705941681339002,0.79661782422644101,"ESR2"]
["GO:0042054","histone methyltransferase activity",0.27705941681339002,0.79661782422644101,"EHMT1"]
["REACT:598","REACT: Lipid digestion, mobilization, and transport",0.27705941681339002,0.79661782422644101,"ABCA1"]
["NCI:89","NCI:HEDGEHOG_GLIPATHWAY",0.27705941681339002,0.79661782422644101,"CSNK1D"]
["NCI:144","NCI:NFAT_TFPATHWAY",0.27705941681339002,0.79661782422644101,"CDK4"]
["GO:0051707","response to other organism",0.27732000299342102,0.796678640847714,"ABCA1;MAPK3;SOD2;IKBKG;TICAM1"]
["GO:0048705","skeletal system morphogenesis",0.27751260681734402,0.796678640847714,"CBS;SKI"]
["GO:0022843","voltage-gated cation channel activity",0.27751260681734402,0.796678640847714,"CACNA1B;KCNH8"]
["GO:0005759","mitochondrial matrix",0.27854665462782502,0.79923241358979702,"DBT;SOD2;PMPCB"]
["GO:0044431","Golgi apparatus part",0.27967082326183601,0.80204198770579405,"FLNA;SREBF1;LARGE;ARHGAP32;RER1;SNX9"]
["GO:0051260","protein homooligomerization",0.28000601362590599,0.80258718517021299,"SKI;SOD2"]
["GO:0015844","monoamine transport",0.28193675870500201,0.80271443600415404,"PARK2"]
["GO:0015908","fatty acid transport",0.28193675870500201,0.80271443600415404,"PRKAB2"]
["GO:0031623","receptor internalization",0.28193675870500201,0.80271443600415404,"RAB5A"]
["GO:0032479","regulation of type I interferon production",0.28193675870500201,0.80271443600415404,"TICAM1"]
["GO:0045638","negative regulation of myeloid cell differentiation",0.28193675870500201,0.80271443600415404,"KLF13"]
["GO:0048663","neuron fate commitment",0.28193675870500201,0.80271443600415404,"ATOH1"]
["GO:0016529","sarcoplasmic reticulum",0.28193675870500201,0.80271443600415404,"CAMK2G"]
["GO:0031234","extrinsic to internal side of plasma membrane",0.28193675870500201,0.80271443600415404,"SNX9"]
["GO:0032587","ruffle membrane",0.28193675870500201,0.80271443600415404,"SYNJ2"]
["GO:0004629","phospholipase C activity",0.28193675870500201,0.80271443600415404,"PLCB1"]
["REACT:729","REACT: Nucleotide Excision Repair",0.28193675870500201,0.80271443600415404,"ERCC6"]
["KEGG:00310","Lysine degradation",0.28193675870500201,0.80271443600415404,"EHMT1"]
["KEGG:04961","Endocrine and other factor-regulated calcium reabsorption",0.28193675870500201,0.80271443600415404,"PLCB1"]
["GO:0051348","negative regulation of transferase activity",0.284991113020857,0.81099322902848803,"ABL1;KAT2B"]
["GO:0043565","sequence-specific DNA binding",0.28664629993167901,0.81191159831127002,"ATOH1;ESR2;ETS1;MAX;ZEB2;UHRF1"]
["GO:0006497","protein lipidation",0.28678150092194898,0.81191159831127002,"ABCA1"]
["GO:0015850","organic alcohol transport",0.28678150092194898,0.81191159831127002,"PARK2"]
["GO:0034763","negative regulation of transmembrane transport",0.28678150092194898,0.81191159831127002,"MAPK7"]
["GO:0046460","neutral lipid biosynthetic process",0.28678150092194898,0.81191159831127002,"SREBF1"]
["GO:0046463","acylglycerol biosynthetic process",0.28678150092194898,0.81191159831127002,"SREBF1"]
["GO:0005884","actin filament",0.28678150092194898,0.81191159831127002,"RAC3"]
["GO:0004402","histone acetyltransferase activity",0.28678150092194898,0.81191159831127002,"KAT2B"]
["GO:0005070","SH3/SH2 adaptor activity",0.28678150092194898,0.81191159831127002,"CRKL"]
["REACT:266","REACT: Cytochrome P450 - arranged by substrate type",0.28678150092194898,0.81191159831127002,"CYP7B1"]
["GO:0009890","negative regulation of biosynthetic process",0.289151206289121,0.81820177656850102,"ESR2;FLNA;GALR1;RFX3;SKI;SMARCA2;PLCB1;EHMT1"]
["GO:0009165","nucleotide biosynthetic process",0.28953363800174797,0.81885244563470505,"ABCA1;FLNA;GALR1"]
["GO:0018108","peptidyl-tyrosine phosphorylation",0.28997323589992502,0.81885244563470505,"ABL1;TNK2"]
["GO:0043410","positive regulation of MAPK cascade",0.28997323589992502,0.81885244563470505,"TAOK2;PLCB1"]
["GO:0004518","nuclease activity",0.28997323589992502,0.81885244563470505,"RNASE1;RNASE6"]
["GO:0009790","embryo development",0.291391199789161,0.81955521610666304,"ATOH1;PIK3CB;MAPK7;SKI;ZEB2;PLCB1;EHMT1"]
["GO:0000819","sister chromatid segregation",0.29159385931527398,0.81955521610666304,"SMC2"]
["GO:0003073","regulation of systemic arterial blood pressure",0.29159385931527398,0.81955521610666304,"SOD2"]
["GO:0006383","transcription from RNA polymerase III promoter",0.29159385931527398,0.81955521610666304,"TBP"]
["GO:0021549","cerebellum development",0.29159385931527398,0.81955521610666304,"CBS"]
["REACT:725","REACT: Nuclear Receptor transcription pathway",0.29159385931527398,0.81955521610666304,"ESR2"]
["NCI:37","NCI:CD8TCRPATHWAY",0.29159385931527398,0.81955521610666304,"IKBKG"]
["NCI:202","NCI:TAP63PATHWAY",0.29159385931527398,0.81955521610666304,"ABL1"]
["GO:0019953","sexual reproduction",0.29164451481702802,0.81955521610666304,"TBP;UBE3A;PLCB1;TSSK2;ZSCAN2"]
["GO:0005216","ion channel activity",0.29170358288395198,0.81955521610666304,"CACNA1B;CHRNA7;GRID2;KCNH8"]
["GO:0006790","sulfur compound metabolic process",0.292462927284383,0.82043859722982104,"CBS;SOD2"]
["GO:0046651","lymphocyte proliferation",0.292462927284383,0.82043859722982104,"PPP3CB;TICAM1"]
["GO:0051146","striated muscle cell differentiation",0.292462927284383,0.82043859722982104,"SKI;PLCB1"]
["GO:0010959","regulation of metal ion transport",0.29495157265188199,0.82554946390135997,"CACNA1B;CAMK2G"]
["GO:0018212","peptidyl-tyrosine modification",0.29495157265188199,0.82554946390135997,"ABL1;TNK2"]
["GO:0031301","integral to organelle membrane",0.29495157265188199,0.82554946390135997,"LARGE;RER1"]
["GO:0001952","regulation of cell-matrix adhesion",0.29637404832033598,0.82554946390135997,"PIK3CB"]
["GO:0007033","vacuole organization",0.29637404832033598,0.82554946390135997,"ABCA1"]
["GO:0014032","neural crest cell development",0.29637404832033598,0.82554946390135997,"ZEB2"]
["GO:0032368","regulation of lipid transport",0.29637404832033598,0.82554946390135997,"ABCA1"]
["GO:0045598","regulation of fat cell differentiation",0.29637404832033598,0.82554946390135997,"SOD2"]
["GO:0005905","coated pit",0.29637404832033598,0.82554946390135997,"TNK2"]
["GO:0016528","sarcoplasm",0.29637404832033598,0.82554946390135997,"CAMK2G"]
["GO:0022625","cytosolic large ribosomal subunit",0.29637404832033598,0.82554946390135997,"RPL19"]
["GO:0003707","steroid hormone receptor activity",0.29637404832033598,0.82554946390135997,"ESR2"]
["REACT:645","REACT: Mitochondrial Protein Import",0.29637404832033598,0.82554946390135997,"PMPCB"]
["KEGG:04742","Taste transduction",0.29637404832033598,0.82554946390135997,"CACNA1B"]
["GO:0032943","mononuclear cell proliferation",0.29743907420971299,0.82809912356725301,"PPP3CB;TICAM1"]
["GO:0019932","second-messenger-mediated signaling",0.29871603006140501,0.83123595487912005,"FLNA;GALR1;NTSR2"]
["GO:0060070","canonical Wnt receptor signaling pathway",0.29992533550304601,0.83373796711908799,"CSNK1D;RAB5A"]
["GO:0001756","somitogenesis",0.30112228096600502,0.83373796711908799,"ZEB2"]
["GO:0006664","glycolipid metabolic process",0.30112228096600502,0.83373796711908799,"LARGE"]
["GO:0007044","cell-substrate junction assembly",0.30112228096600502,0.83373796711908799,"TAOK2"]
["GO:0008344","adult locomotory behavior",0.30112228096600502,0.83373796711908799,"PARK2"]
["GO:0050728","negative regulation of inflammatory response",0.30112228096600502,0.83373796711908799,"MAPK7"]
["GO:0050871","positive regulation of B cell activation",0.30112228096600502,0.83373796711908799,"TICAM1"]
["GO:0090317","negative regulation of intracellular protein transport",0.30112228096600502,0.83373796711908799,"MAPK7"]
["GO:0005814","centriole",0.30112228096600502,0.83373796711908799,"TSSK2"]
["GO:0042641","actomyosin",0.30112228096600502,0.83373796711908799,"KAT2B"]
["GO:0022838","substrate-specific channel activity",0.30533098304885697,0.84174132809212898,"CACNA1B;CHRNA7;GRID2;KCNH8"]
["GO:0009451","RNA modification",0.30583876888380002,0.84174132809212898,"WDR4"]
["GO:0030010","establishment of cell polarity",0.30583876888380002,0.84174132809212898,"PARD3"]
["GO:0032606","type I interferon production",0.30583876888380002,0.84174132809212898,"TICAM1"]
["GO:0032649","regulation of interferon-gamma production",0.30583876888380002,0.84174132809212898,"IL1RL1"]
["GO:0042307","positive regulation of protein import into nucleus",0.30583876888380002,0.84174132809212898,"FLNA"]
["GO:0042632","cholesterol homeostasis",0.30583876888380002,0.84174132809212898,"ABCA1"]
["GO:0055092","sterol homeostasis",0.30583876888380002,0.84174132809212898,"ABCA1"]
["GO:0005097","Rab GTPase activator activity",0.30583876888380002,0.84174132809212898,"SYNGAP1"]
["REACT:477","REACT: Golgi Associated Vesicle Biogenesis",0.30583876888380002,0.84174132809212898,"SNX9"]
["NCI:76","NCI:FGF_PATHWAY",0.30583876888380002,0.84174132809212898,"MAPK3"]
["NCI:217","NCI:TXA2PATHWAY",0.30583876888380002,0.84174132809212898,"MAPK11"]
["KEGG:04141","Protein processing in endoplasmic reticulum",0.30737573303792298,0.84555074846633005,"MAPK8;PARK2"]
["GO:0005261","cation channel activity",0.30791629104382101,0.84661676046442103,"CACNA1B;CHRNA7;KCNH8"]
["GO:0019935","cyclic-nucleotide-mediated signaling",0.30985609502023498,0.85082577110324997,"FLNA;GALR1"]
["GO:0014013","regulation of gliogenesis",0.31052372231696701,0.85082577110324997,"SKI"]
["GO:0042100","B cell proliferation",0.31052372231696701,0.85082577110324997,"TICAM1"]
["GO:0042158","lipoprotein biosynthetic process",0.31052372231696701,0.85082577110324997,"ABCA1"]
["GO:0046504","glycerol ether biosynthetic process",0.31052372231696701,0.85082577110324997,"SREBF1"]
["GO:0071383","cellular response to steroid hormone stimulus",0.31052372231696701,0.85082577110324997,"ESR2"]
["KEGG:05130","Pathogenic Escherichia coli infection",0.31052372231696701,0.85082577110324997,"ABL1"]
["GO:0046883","regulation of hormone secretion",0.31233475407136402,0.85536428689246902,"PPP3CB;RFX3"]
["GO:0015837","amine transport",0.31481162148891301,0.85805172289192599,"PARK2;PRKAB2"]
["GO:0046777","protein autophosphorylation",0.31481162148891301,0.85805172289192599,"MAPK7;TSSK2"]
["GO:0070661","leukocyte proliferation",0.31481162148891301,0.85805172289192599,"PPP3CB;TICAM1"]
["GO:0016571","histone methylation",0.31517735012949999,0.85805172289192599,"EHMT1"]
["GO:0021536","diencephalon development",0.31517735012949999,0.85805172289192599,"ETS1"]
["GO:0021782","glial cell development",0.31517735012949999,0.85805172289192599,"SKI"]
["GO:0032387","negative regulation of intracellular transport",0.31517735012949999,0.85805172289192599,"MAPK7"]
["GO:0001948","glycoprotein binding",0.31517735012949999,0.85805172289192599,"FLNA"]
["GO:0019955","cytokine binding",0.31517735012949999,0.85805172289192599,"IL1RL1"]
["GO:0030170","pyridoxal phosphate binding",0.31517735012949999,0.85805172289192599,"CBS"]
["GO:0070279","vitamin B6 binding",0.31517735012949999,0.85805172289192599,"CBS"]
["KEGG:04340","Hedgehog signaling pathway",0.31517735012949999,0.85805172289192599,"CSNK1D"]
["GO:0009607","response to biotic stimulus",0.31668941911307902,0.860891885400067,"ABCA1;MAPK3;SOD2;IKBKG;TICAM1"]
["GO:0007517","muscle organ development",0.31712870301854901,0.860891885400067,"MAPK12;SKI;PLCB1"]
["REACT:563","REACT: Interferon Signaling",0.31728660981780199,0.860891885400067,"CAMK2G;MAPK3"]
["GO:0051240","positive regulation of multicellular organismal process",0.31750525437388799,0.860891885400067,"IL1RL1;NRXN1;PLCB1;TICAM1"]
["GO:0000122","negative regulation of transcription from RNA polymerase II promoter",0.31903035828844201,0.860891885400067,"ESR2;SKI;SMARCA2;EHMT1"]
["GO:0002460","adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains",0.31975963283777797,0.860891885400067,"PPP3CB;IL1RL1"]
["GO:0016747","transferase activity, transferring acyl groups other than amino-acyl groups",0.31975963283777797,0.860891885400067,"DBT;KAT2B"]
["GO:0007200","activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger",0.31979985981510101,0.860891885400067,"NTSR2"]
["GO:0019827","stem cell maintenance",0.31979985981510101,0.860891885400067,"SKI"]
["GO:0022037","metencephalon development",0.31979985981510101,0.860891885400067,"CBS"]
["GO:0032609","interferon-gamma production",0.31979985981510101,0.860891885400067,"IL1RL1"]
["GO:0042108","positive regulation of cytokine biosynthetic process",0.31979985981510101,0.860891885400067,"TICAM1"]
["GO:0042384","cilium assembly",0.31979985981510101,0.860891885400067,"RFX3"]
["GO:0045666","positive regulation of neuron differentiation",0.31979985981510101,0.860891885400067,"ATOH1"]
["GO:0061136","regulation of proteasomal protein catabolic process",0.31979985981510101,0.860891885400067,"CSNK1D"]
["GO:0001669","acrosomal vesicle",0.31979985981510101,0.860891885400067,"TSSK2"]
["GO:0005901","caveola",0.31979985981510101,0.860891885400067,"MAPK3"]
["GO:0034708","methyltransferase complex",0.31979985981510101,0.860891885400067,"MAX"]
["GO:0035097","histone methyltransferase complex",0.31979985981510101,0.860891885400067,"MAX"]
["GO:0016209","antioxidant activity",0.31979985981510101,0.860891885400067,"SOD2"]
["REACT:817","REACT: Pre-NOTCH Expression and Processing",0.31979985981510101,0.860891885400067,"KAT2B"]
["KEGG:00140","Steroid hormone biosynthesis",0.31979985981510101,0.860891885400067,"CYP7B1"]
["NCI:17","NCI:AR_PATHWAY",0.31979985981510101,0.860891885400067,"UBE3A"]
["GO:0034654","nucleobase-containing compound biosynthetic process",0.32081582165974198,0.86320677306502602,"ABCA1;FLNA;GALR1"]
["GO:0006813","potassium ion transport",0.322230605551037,0.866591983426513,"CDK2;KCNH8"]
["GO:0001933","negative regulation of protein phosphorylation",0.324391457506084,0.86986599269203102,"PARK2"]
["GO:0030510","regulation of BMP signaling pathway",0.324391457506084,0.86986599269203102,"SKI"]
["GO:0045862","positive regulation of proteolysis",0.324391457506084,0.86986599269203102,"CSNK1D"]
["GO:0050821","protein stabilization",0.324391457506084,0.86986599269203102,"FLNA"]
["GO:0016835","carbon-oxygen lyase activity",0.324391457506084,0.86986599269203102,"CBS"]
["REACT:871","REACT: RNA Polymerase II Pre-transcription Events",0.324391457506084,0.86986599269203102,"TBP"]
["GO:0034623","cellular macromolecular complex disassembly",0.32469944416994601,0.87027002187409996,"RPL19;BAZ1B"]
["GO:0009055","electron carrier activity",0.32716606610488103,0.87645650251438201,"CYP7B1;STEAP3"]
["GO:0007009","plasma membrane organization",0.328952347982226,0.87868874410317499,"NRXN1"]
["GO:0030148","sphingolipid biosynthetic process",0.328952347982226,0.87868874410317499,"LARGE"]
["GO:0030301","cholesterol transport",0.328952347982226,0.87868874410317499,"ABCA1"]
["GO:0051297","centrosome organization",0.328952347982226,0.87868874410317499,"CDK2"]
["GO:0017053","transcriptional repressor complex",0.328952347982226,0.87868874410317499,"SKI"]
["REACT:215","REACT: Cell-cell junction organization",0.328952347982226,0.87868874410317499,"PARD3"]
["GO:0003723","RNA binding",0.33039100326801901,0.88210570949743305,"RPL19;SNRPN;SYNJ2;SYNCRIP;STAU2;MSI2;DDX53"]
["GO:0031406","carboxylic acid binding",0.33209233548210298,0.88523343965800405,"CBS;DBI"]
["GO:0015267","channel activity",0.33278246311052001,0.88523343965800405,"CACNA1B;CHRNA7;GRID2;KCNH8"]
["GO:0022803","passive transmembrane transporter activity",0.33278246311052001,0.88523343965800405,"CACNA1B;CHRNA7;GRID2;KCNH8"]
["GO:0006661","phosphatidylinositol biosynthetic process",0.33348273467955197,0.88523343965800405,"PIK3CB"]
["GO:0007416","synapse assembly",0.33348273467955197,0.88523343965800405,"NRXN1"]
["GO:0014033","neural crest cell differentiation",0.33348273467955197,0.88523343965800405,"ZEB2"]
["GO:0015918","sterol transport",0.33348273467955197,0.88523343965800405,"ABCA1"]
["GO:0032675","regulation of interleukin-6 production",0.33348273467955197,0.88523343965800405,"TICAM1"]
["GO:0044272","sulfur compound biosynthetic process",0.33348273467955197,0.88523343965800405,"CBS"]
["GO:0071295","cellular response to vitamin",0.33348273467955197,0.88523343965800405,"ABCA1"]
["GO:0043679","axon terminus",0.33348273467955197,0.88523343965800405,"SYNJ2"]
["NCI:109","NCI:IL4_2PATHWAY",0.33348273467955197,0.88523343965800405,"ETS1"]
["GO:0006875","cellular metal ion homeostasis",0.33372406628144702,0.88544917729926298,"CHRNA7;PIK3CB;STEAP3"]
["GO:0048598","embryonic morphogenesis",0.33431291285953202,0.88658630581923903,"ATOH1;MAPK7;SKI;ZEB2"]
["GO:0010638","positive regulation of organelle organization",0.33455182362716301,0.88679477158862796,"LIMK1;MAPK3"]
["GO:0007346","regulation of mitotic cell cycle",0.33556796061385502,0.88906224047693705,"CDK2;PSMB1;PSMC2"]
["GO:0016054","organic acid catabolic process",0.337008776470198,0.88991954239659199,"CBS;DBT"]
["GO:0032984","macromolecular complex disassembly",0.337008776470198,0.88991954239659199,"RPL19;BAZ1B"]
["GO:0045926","negative regulation of growth",0.337008776470198,0.88991954239659199,"ESR2;SMARCA2"]
["GO:0046395","carboxylic acid catabolic process",0.337008776470198,0.88991954239659199,"CBS;DBT"]
["GO:0006954","inflammatory response",0.33737497139627898,0.88991954239659199,"MAPK7;IKBKG;IL1RL1;TICAM1"]
["GO:0010469","regulation of receptor activity",0.33798281969906702,0.88991954239659199,"NRXN1"]
["GO:0022407","regulation of cell-cell adhesion",0.33798281969906702,0.88991954239659199,"MAPK7"]
["GO:0034764","positive regulation of transmembrane transport",0.33798281969906702,0.88991954239659199,"FLNA"]
["GO:0046467","membrane lipid biosynthetic process",0.33798281969906702,0.88991954239659199,"LARGE"]
["GO:0030658","transport vesicle membrane",0.33798281969906702,0.88991954239659199,"SREBF1"]
["REACT:240","REACT: Clathrin derived vesicle budding",0.33798281969906702,0.88991954239659199,"SNX9"]
["REACT:1164","REACT: Transcription of the HIV genome",0.33798281969906702,0.88991954239659199,"TBP"]
["REACT:1285","REACT: trans-Golgi Network Vesicle Budding",0.33798281969906702,0.88991954239659199,"SNX9"]
["GO:0004857","enzyme inhibitor activity",0.339255229537959,0.89284487621502895,"SKI;KAT2B;TNK2"]
["GO:0060249","anatomical structure homeostasis",0.34191477026384298,0.89784308564314097,"PPP3CB;LARGE"]
["GO:0007190","activation of adenylate cyclase activity",0.34245280381544302,0.89784308564314097,"GALR1"]
["GO:0009895","negative regulation of catabolic process",0.34245280381544302,0.89784308564314097,"FLNA"]
["GO:0019233","sensory perception of pain",0.34245280381544302,0.89784308564314097,"MAPK3"]
["GO:0032635","interleukin-6 production",0.34245280381544302,0.89784308564314097,"TICAM1"]
["GO:0061053","somite development",0.34245280381544302,0.89784308564314097,"ZEB2"]
["GO:0001104","RNA polymerase II transcription cofactor activity",0.34245280381544302,0.89784308564314097,"SMARCA2"]
["KEGG:04623","Cytosolic DNA-sensing pathway",0.34245280381544302,0.89784308564314097,"IKBKG"]
["GO:0050678","regulation of epithelial cell proliferation",0.34436366102787502,0.90199799848778694,"ESR2;CYP7B1"]
["GO:0030136","clathrin-coated vesicle",0.34436366102787502,0.90199799848778694,"TNK2;SNX9"]
["GO:0031300","intrinsic to organelle membrane",0.34680971609394901,0.90562125910263802,"LARGE;RER1"]
["GO:0001708","cell fate specification",0.34689288648562699,0.90562125910263802,"ATOH1"]
["GO:0045762","positive regulation of adenylate cyclase activity",0.34689288648562699,0.90562125910263802,"GALR1"]
["GO:0050707","regulation of cytokine secretion",0.34689288648562699,0.90562125910263802,"IL1RL1"]
["GO:0050729","positive regulation of inflammatory response",0.34689288648562699,0.90562125910263802,"IL1RL1"]
["GO:0008170","N-methyltransferase activity",0.34689288648562699,0.90562125910263802,"EHMT1"]
["NCI:62","NCI:ERA_GENOMIC_PATHWAY",0.34689288648562699,0.90562125910263802,"ESR2"]
["GO:0006913","nucleocytoplasmic transport",0.34846848495156102,0.90930549941133598,"FLNA;MAPK3;MAPK7"]
["GO:0033365","protein localization to organelle",0.349635014965265,0.91026213898044095,"FLNA;MAPK3;MAPK7;RPL19"]
["GO:0006304","DNA modification",0.351303265857419,0.91026213898044095,"EHMT1"]
["GO:0007043","cell-cell junction assembly",0.351303265857419,0.91026213898044095,"PARD3"]
["GO:0031023","microtubule organizing center organization",0.351303265857419,0.91026213898044095,"CDK2"]
["GO:0031281","positive regulation of cyclase activity",0.351303265857419,0.91026213898044095,"GALR1"]
["GO:0042552","myelination",0.351303265857419,0.91026213898044095,"SKI"]
["GO:0045744","negative regulation of G-protein coupled receptor protein signaling pathway",0.351303265857419,0.91026213898044095,"SNX14"]
["GO:0046824","positive regulation of nucleocytoplasmic transport",0.351303265857419,0.91026213898044095,"FLNA"]
["GO:0046887","positive regulation of hormone secretion",0.351303265857419,0.91026213898044095,"PPP3CB"]
["GO:0051341","regulation of oxidoreductase activity",0.351303265857419,0.91026213898044095,"ABL1"]
["GO:0090101","negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway",0.351303265857419,0.91026213898044095,"SKI"]
["GO:0008276","protein methyltransferase activity",0.351303265857419,0.91026213898044095,"EHMT1"]
["GO:0035591","signaling adaptor activity",0.351303265857419,0.91026213898044095,"CRKL"]
["REACT:211","REACT: Cell death signalling via NRAGE, NRIF and NADE",0.351303265857419,0.91026213898044095,"MAPK8"]
["NCI:100","NCI:IL12_2PATHWAY",0.351303265857419,0.91026213898044095,"PPP3CB"]
["GO:0002250","adaptive immune response",0.35169303086320097,0.91084543386480699,"PPP3CB;IL1RL1"]
["GO:0051169","nuclear transport",0.353991481141189,0.91636915005758401,"FLNA;MAPK3;MAPK7"]
["GO:0007422","peripheral nervous system development",0.355684138777973,0.91688940154694598,"SKI"]
["GO:0018958","phenol-containing compound metabolic process",0.355684138777973,0.91688940154694598,"PARK2"]
["GO:0032412","regulation of ion transmembrane transporter activity",0.355684138777973,0.91688940154694598,"CACNA1B"]
["GO:0045732","positive regulation of protein catabolic process",0.355684138777973,0.91688940154694598,"CSNK1D"]
["GO:0005319","lipid transporter activity",0.355684138777973,0.91688940154694598,"ABCA1"]
["GO:0019903","protein phosphatase binding",0.355684138777973,0.91688940154694598,"PPP3CB"]
["GO:0033293","monocarboxylic acid binding",0.355684138777973,0.91688940154694598,"DBI"]
["NCI:92","NCI:HIF1_TFPATHWAY",0.355684138777973,0.91688940154694598,"ETS1"]
["NCI:132","NCI:LYSOPHOSPHOLIPID_PATHWAY",0.355684138777973,0.91688940154694598,"PIK3CB"]
["GO:0008168","methyltransferase activity",0.35656414878797299,0.91830208151539505,"WDR4;EHMT1"]
["REACT:409","REACT: G alpha (q) signalling events",0.35656414878797299,0.91830208151539505,"NTSR2;PLCB1"]
["GO:0010608","posttranscriptional regulation of gene expression",0.357670766308754,0.92072344309912801,"FLNA;MAPK3;SYNCRIP"]
["GO:0005624","membrane fraction",0.35796557425980802,0.92105374735128398,"ABCA1;GRID2;SYNGAP1;CYP7B1;SYNCRIP;CYFIP1;PLCB1"]
["REACT:780","REACT: Peptide ligand-binding receptors",0.35899496177380602,0.92327295608214399,"GALR1;NTSR2"]
["GO:0045892","negative regulation of transcription, DNA-dependent",0.35931187090719302,0.92337389746782195,"ESR2;RFX3;SKI;SMARCA2;PLCB1;EHMT1"]
["GO:0008361","regulation of cell size",0.360035700802258,0.92337389746782195,"LIMK1"]
["GO:0051349","positive regulation of lyase activity",0.360035700802258,0.92337389746782195,"GALR1"]
["GO:0060021","palate development",0.360035700802258,0.92337389746782195,"SKI"]
["GO:0044306","neuron projection terminus",0.360035700802258,0.92337389746782195,"SYNJ2"]
["REACT:1001","REACT: Semaphorin interactions",0.360035700802258,0.92337389746782195,"LIMK1"]
["GO:0008380","RNA splicing",0.36134752710032197,0.92607197148188602,"SNRPN;WTAP;SYNCRIP"]
["GO:0043269","regulation of ion transport",0.361422521046528,0.92607197148188602,"CACNA1B;CAMK2G"]
["GO:0006869","lipid transport",0.36384676059701299,0.92971829556571906,"ABCA1;PRKAB2"]
["GO:0008406","gonad development",0.36384676059701299,0.92971829556571906,"ESR2;UBE3A"]
["GO:0019216","regulation of lipid metabolic process",0.36384676059701299,0.92971829556571906,"PRKAB2;SREBF1"]
["GO:0001906","cell killing",0.36435814620146001,0.92971829556571906,"PPP3CB"]
["GO:0006879","cellular iron ion homeostasis",0.36435814620146001,0.92971829556571906,"STEAP3"]
["GO:0006941","striated muscle contraction",0.36435814620146001,0.92971829556571906,"DTNA"]
["GO:0019217","regulation of fatty acid metabolic process",0.36435814620146001,0.92971829556571906,"PRKAB2"]
["GO:0031348","negative regulation of defense response",0.36435814620146001,0.92971829556571906,"MAPK7"]
["GO:0048016","inositol phosphate-mediated signaling",0.36435814620146001,0.92971829556571906,"NTSR2"]
["GO:0050662","coenzyme binding",0.36626761543338199,0.9341597273294,"DBI;STEAP3"]
["GO:0007272","ensheathment of neurons",0.36865166797132598,0.93816262158609898,"SKI"]
["GO:0008366","axon ensheathment",0.36865166797132598,0.93816262158609898,"SKI"]
["GO:0017015","regulation of transforming growth factor beta receptor signaling pathway",0.36865166797132598,0.93816262158609898,"SKI"]
["GO:0051591","response to cAMP",0.36865166797132598,0.93816262158609898,"CYP7B1"]
["GO:0031589","cell-substrate adhesion",0.36868502157053101,0.93816262158609898,"PIK3CB;TAOK2"]
["GO:0005783","endoplasmic reticulum",0.36889181348956901,0.93825724699967705,"CAMK2G;PARK2;PCYT1A;SREBF1;CYP7B1;ARHGAP32;SYNCRIP;STAU2;SCAPER"]
["GO:0055065","metal ion homeostasis",0.37052643379431299,0.94198172414988002,"CHRNA7;PIK3CB;STEAP3"]
["GO:0016741","transferase activity, transferring one-carbon groups",0.37109891601975897,0.94300376822292498,"WDR4;EHMT1"]
["GO:0002064","epithelial cell development",0.37291645784045901,0.94545089128021098,"ESR2"]
["GO:0007286","spermatid development",0.37291645784045901,0.94545089128021098,"TSSK2"]
["REACT:565","REACT: Interferon gamma signaling",0.37291645784045901,0.94545089128021098,"CAMK2G"]
["REACT:783","REACT: Phase 1 - Functionalization of compounds",0.37291645784045901,0.94545089128021098,"CYP7B1"]
["NCI:11","NCI:AP1_PATHWAY",0.37291645784045901,0.94545089128021098,"ETS1"]
["GO:0006368","transcription elongation from RNA polymerase II promoter",0.37715270627856001,0.954441340865961,"TBP"]
["GO:0022898","regulation of transmembrane transporter activity",0.37715270627856001,0.954441340865961,"CACNA1B"]
["GO:0019208","phosphatase regulator activity",0.37715270627856001,0.954441340865961,"ZEB2"]
["REACT:675","REACT: NCAM signaling for neurite out-growth",0.37715270627856001,0.954441340865961,"MAPK3"]
["GO:0002706","regulation of lymphocyte mediated immunity",0.38136060250461101,0.96244838186838799,"PPP3CB"]
["GO:0031670","cellular response to nutrient",0.38136060250461101,0.96244838186838799,"ABCA1"]
["GO:0050680","negative regulation of epithelial cell proliferation",0.38136060250461101,0.96244838186838799,"ESR2"]
["GO:0090316","positive regulation of intracellular protein transport",0.38136060250461101,0.96244838186838799,"FLNA"]
["GO:0031674","I band",0.38136060250461101,0.96244838186838799,"KAT2B"]
["KEGG:03320","PPAR signaling pathway",0.38136060250461101,0.96244838186838799,"DBI"]
["GO:0043010","camera-type eye development",0.38311357680209002,0.96643151248023795,"MAX;SKI"]
["GO:0071705","nitrogen compound transport",0.385505132874843,0.969018232815272,"PARK2;PRKAB2"]
["GO:0002685","regulation of leukocyte migration",0.38554033449501302,0.969018232815272,"PLCB1"]
["GO:0006944","cellular membrane fusion",0.38554033449501302,0.969018232815272,"RIMS1"]
["GO:0048515","spermatid differentiation",0.38554033449501302,0.969018232815272,"TSSK2"]
["GO:0050714","positive regulation of protein secretion",0.38554033449501302,0.969018232815272,"IL1RL1"]
["GO:2001020","regulation of response to DNA damage stimulus",0.38554033449501302,0.969018232815272,"ABL1"]
["REACT:114","REACT: Antiviral mechanism by IFN-stimulated genes",0.38554033449501302,0.969018232815272,"MAPK3"]
["REACT:522","REACT: ISG15 antiviral mechanism",0.38554033449501302,0.969018232815272,"MAPK3"]
["GO:0005244","voltage-gated ion channel activity",0.38789276338534201,0.973702184418207,"CACNA1B;KCNH8"]
["GO:0022832","voltage-gated channel activity",0.38789276338534201,0.973702184418207,"CACNA1B;KCNH8"]
["GO:0051253","negative regulation of RNA metabolic process",0.38959950399064103,0.973702184418207,"ESR2;RFX3;SKI;SMARCA2;PLCB1;EHMT1"]
["GO:0006289","nucleotide-excision repair",0.38969208899166902,0.973702184418207,"ERCC6"]
["GO:0006518","peptide metabolic process",0.38969208899166902,0.973702184418207,"SOD2"]
["GO:0007368","determination of left/right symmetry",0.38969208899166902,0.973702184418207,"RFX3"]
["GO:0031016","pancreas development",0.38969208899166902,0.973702184418207,"RFX3"]
["GO:0042537","benzene-containing compound metabolic process",0.38969208899166902,0.973702184418207,"PARK2"]
["GO:0051494","negative regulation of cytoskeleton organization",0.38969208899166902,0.973702184418207,"PARK2"]
["GO:0061351","neural precursor cell proliferation",0.38969208899166902,0.973702184418207,"ZEB2"]
["GO:0030666","endocytic vesicle membrane",0.38969208899166902,0.973702184418207,"CAMK2G"]
["REACT:1033","REACT: Signaling by NOTCH1",0.38969208899166902,0.973702184418207,"KAT2B"]
["NCI:26","NCI:AVB3_INTEGRIN_PATHWAY",0.38969208899166902,0.973702184418207,"MAPK3"]
["GO:0007600","sensory perception",0.39101282300114798,0.97656114530128602,"ERCC6;MAPK3;RIMS1;NTSR2"]
["GO:0006479","protein methylation",0.39381605151000698,0.98002267069426796,"EHMT1"]
["GO:0006690","icosanoid metabolic process",0.39381605151000698,0.98002267069426796,"MAPK3"]
["GO:0008213","protein alkylation",0.39381605151000698,0.98002267069426796,"EHMT1"]
["GO:0051262","protein tetramerization",0.39381605151000698,0.98002267069426796,"SOD2"]
["GO:0055088","lipid homeostasis",0.39381605151000698,0.98002267069426796,"ABCA1"]
["GO:0061025","membrane fusion",0.39381605151000698,0.98002267069426796,"RIMS1"]
["GO:0000123","histone acetyltransferase complex",0.39381605151000698,0.98002267069426796,"KAT2B"]
["GO:0015934","large ribosomal subunit",0.39381605151000698,0.98002267069426796,"RPL19"]
["GO:0003779","actin binding",0.39609546608089802,0.98525185178036201,"ABL1;FLNA;CYFIP1"]
["GO:0007601","visual perception",0.39740293574916102,0.98799435902667099,"ERCC6;RIMS1"]
["GO:0009953","dorsal/ventral pattern formation",0.39791240634696701,0.98799435902667099,"MAPK8"]
["GO:0048593","camera-type eye morphogenesis",0.39791240634696701,0.98799435902667099,"SKI"]
["GO:0008080","N-acetyltransferase activity",0.39791240634696701,0.98799435902667099,"KAT2B"]
["GO:0050953","sensory perception of light stimulus",0.39977012574411303,0.99216165797058398,"ERCC6;RIMS1"]
["GO:0030003","cellular cation homeostasis",0.401542900331463,0.99534682349055104,"CHRNA7;PIK3CB;STEAP3"]
["GO:0009798","axis specification",0.40198133658892199,0.99534682349055104,"SKI"]
["GO:0032388","positive regulation of intracellular transport",0.40198133658892199,0.99534682349055104,"FLNA"]
["GO:0034765","regulation of ion transmembrane transport",0.40198133658892199,0.99534682349055104,"CACNA1B"]
["REACT:859","REACT: RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways",0.40198133658892199,0.99534682349055104,"IKBKG"]
["GO:0006401","RNA catabolic process",0.402133071312614,0.99534682349055104,"RNASE6;RPL19"]
["GO:0000280","nuclear division",0.40335584060804103,0.99748078240665305,"CDK2;FLNA;SMC2"]
["GO:0007067","mitosis",0.40335584060804103,0.99748078240665305,"CDK2;FLNA;SMC2"]
["GO:0015718","monocarboxylic acid transport",0.40602302411955599,1,"PRKAB2"]
["GO:0016202","regulation of striated muscle tissue development",0.40602302411955599,1,"PLCB1"]
["GO:0019897","extrinsic to plasma membrane",0.40602302411955599,1,"SNX9"]
["GO:0031461","cullin-RING ubiquitin ligase complex",0.40602302411955599,1,"CUL2"]
["GO:0050660","flavin adenine dinucleotide binding",0.40602302411955599,1,"STEAP3"]
["GO:0060562","epithelial tube morphogenesis",0.40684602970711098,1,"SKI;ZEB2"]
["GO:0018130","heterocycle biosynthetic process",0.40878561336240399,1,"ABCA1;FLNA;GALR1"]
["GO:0019228","regulation of action potential in neuron",0.41003764962768602,1,"SKI"]
["GO:0033559","unsaturated fatty acid metabolic process",0.41003764962768602,1,"MAPK3"]
["GO:0050864","regulation of B cell activation",0.41003764962768602,1,"TICAM1"]
["GO:0001076","RNA polymerase II transcription factor binding transcription factor activity",0.41003764962768602,1,"SMARCA2"]
["REACT:798","REACT: Platelet degranulation",0.41003764962768602,1,"FLNA"]
["REACT:1040","REACT: Signaling by SCF-KIT",0.41003764962768602,1,"MAPK3"]
["KEGG:04146","Peroxisome",0.41003764962768602,1,"SOD2"]
["GO:0045137","development of primary sexual characteristics",0.41154142046599301,1,"ESR2;UBE3A"]
["GO:0007219","Notch signaling pathway",0.41402539261504101,1,"KAT2B"]
["GO:0048634","regulation of muscle organ development",0.41402539261504101,1,"PLCB1"]
["GO:0060333","interferon-gamma-mediated signaling pathway",0.41402539261504101,1,"CAMK2G"]
["GO:0010817","regulation of hormone levels",0.414201175773109,1,"CAMK2G;PPP3CB;RFX3"]
["GO:0043524","negative regulation of neuron apoptosis",0.417986431403985,1,"SOD2"]
["GO:0060271","cilium morphogenesis",0.417986431403985,1,"RFX3"]
["GO:0071013","catalytic step 2 spliceosome",0.417986431403985,1,"SYNCRIP"]
["GO:0004896","cytokine receptor activity",0.417986431403985,1,"IL1RL1"]
["GO:0050673","epithelial cell proliferation",0.41855074589090902,1,"ESR2;CYP7B1"]
["GO:2000145","regulation of cell motility",0.41960172481907598,1,"ABL1;ETS1;PLCB1"]
["GO:0006367","transcription initiation from RNA polymerase II promoter",0.42192094314518902,1,"TBP"]
["GO:0006909","phagocytosis",0.42192094314518902,1,"ABCA1"]
["GO:0009791","post-embryonic development",0.42192094314518902,1,"SOD2"]
["GO:0031256","leading edge membrane",0.42192094314518902,1,"SYNJ2"]
["GO:0000087","M phase of mitotic cell cycle",0.423193363015054,1,"CDK2;FLNA;SMC2"]
["GO:0010876","lipid localization",0.42551848061574399,1,"ABCA1;PRKAB2"]
["GO:0002576","platelet degranulation",0.42582910382525901,1,"FLNA"]
["GO:0016458","gene silencing",0.42582910382525901,1,"CDK2"]
["GO:0032409","regulation of transporter activity",0.42582910382525901,1,"CACNA1B"]
["GO:0042472","inner ear morphogenesis",0.42582910382525901,1,"ATOH1"]
["GO:0047485","protein N-terminus binding",0.42582910382525901,1,"ERCC6"]
["GO:0001501","skeletal system development",0.42677775397620199,1,"CBS;MAPK3;SKI"]
["GO:0034702","ion channel complex",0.42783161521295598,1,"CACNA1B;CHRNA7"]
["GO:0048285","organelle fission",0.428567162044863,1,"CDK2;FLNA;SMC2"]
["GO:0008033","tRNA processing",0.42971108827431098,1,"WDR4"]
["GO:0016050","vesicle organization",0.42971108827431098,1,"ABCA1"]
["GO:0019395","fatty acid oxidation",0.42971108827431098,1,"PRKAB2"]
["GO:0035282","segmentation",0.42971108827431098,1,"ZEB2"]
["GO:0043279","response to alkaloid",0.42971108827431098,1,"CHRNA7"]
["GO:0060759","regulation of response to cytokine stimulus",0.42971108827431098,1,"MAPK7"]
["GO:0071241","cellular response to inorganic substance",0.42971108827431098,1,"CDK2"]
["REACT:962","REACT: Response to elevated platelet cytosolic Ca2+",0.42971108827431098,1,"FLNA"]
["KEGG:05410","Hypertrophic cardiomyopathy (HCM)",0.42971108827431098,1,"PRKAB2"]
["GO:0000079","regulation of cyclin-dependent protein kinase activity",0.43356707017349799,1,"KAT2B"]
["GO:0001101","response to acid",0.43356707017349799,1,"CBS"]
["GO:0001667","ameboidal cell migration",0.43356707017349799,1,"ZEB2"]
["GO:0001889","liver development",0.43356707017349799,1,"SOD2"]
["GO:0030307","positive regulation of cell growth",0.43356707017349799,1,"LIMK1"]
["GO:0031334","positive regulation of protein complex assembly",0.43356707017349799,1,"SNX9"]
["GO:0045667","regulation of osteoblast differentiation",0.43356707017349799,1,"SKI"]
["REACT:355","REACT: Eukaryotic Translation Termination",0.43356707017349799,1,"RPL19"]
["REACT:778","REACT: Peptide chain elongation",0.43356707017349799,1,"RPL19"]
["KEGG:04350","TGF-beta signaling pathway",0.43356707017349799,1,"MAPK3"]
["GO:0016337","cell-cell adhesion",0.435705574334185,1,"PIK3CB;MAPK7;NRXN1"]
["GO:0016597","amino acid binding",0.43739722206249199,1,"CBS"]
["KEGG:00564","Glycerophospholipid metabolism",0.43739722206249199,1,"PCYT1A"]
["GO:0034440","lipid oxidation",0.441201715346908,1,"PRKAB2"]
["GO:0061008","hepaticobiliary system development",0.441201715346908,1,"SOD2"]
["GO:0031072","heat shock protein binding",0.441201715346908,1,"LIMK1"]
["REACT:469","REACT: Glycerophospholipid biosynthesis",0.441201715346908,1,"PCYT1A"]
["GO:0000139","Golgi membrane",0.44259233600492798,1,"SREBF1;LARGE;ARHGAP32;RER1"]
["GO:0045111","intermediate filament cytoskeleton",0.44388719342758398,1,"SMARCA2;DLGAP2"]
["GO:0006839","mitochondrial transport",0.44498072030569202,1,"PRKAB2"]
["GO:0010810","regulation of cell-substrate adhesion",0.44498072030569202,1,"PIK3CB"]
["GO:0032526","response to retinoic acid",0.44498072030569202,1,"ABCA1"]
["GO:0000922","spindle pole",0.44498072030569202,1,"TUBGCP5"]
["GO:0016591","DNA-directed RNA polymerase II, holoenzyme",0.44498072030569202,1,"TBP"]
["GO:0008017","microtubule binding",0.44498072030569202,1,"TUBGCP5"]
["REACT:353","REACT: Eukaryotic Translation Elongation",0.44498072030569202,1,"RPL19"]
["GO:0007283","spermatogenesis",0.44635261826892197,1,"TBP;TSSK2;ZSCAN2"]
["GO:0048232","male gamete generation",0.44635261826892197,1,"TBP;TSSK2;ZSCAN2"]
["GO:0007423","sensory organ development",0.4481197280941,1,"ATOH1;MAX;SKI"]
["GO:2000243","positive regulation of reproductive process",0.448734406098454,1,"PLCB1"]
["GO:0005262","calcium channel activity",0.448734406098454,1,"CACNA1B"]
["GO:0008144","drug binding",0.448734406098454,1,"PPP3CB"]
["GO:0060429","epithelium development",0.45158004916593403,1,"ESR2;SKI;CYP7B1;ZEB2"]
["GO:0002703","regulation of leukocyte mediated immunity",0.45246294077275701,1,"PPP3CB"]
["GO:0006275","regulation of DNA replication",0.45246294077275701,1,"CDK2"]
["GO:0033500","carbohydrate homeostasis",0.45246294077275701,1,"PPP3CB"]
["GO:0042035","regulation of cytokine biosynthetic process",0.45246294077275701,1,"TICAM1"]
["GO:0042593","glucose homeostasis",0.45246294077275701,1,"PPP3CB"]
["GO:0051495","positive regulation of cytoskeleton organization",0.45246294077275701,1,"LIMK1"]
["GO:0016407","acetyltransferase activity",0.45246294077275701,1,"KAT2B"]
["REACT:719","REACT: Nonsense Mediated Decay Independent of the Exon Junction Complex",0.45246294077275701,1,"RPL19"]
["KEGG:04727","GABAergic synapse",0.45246294077275701,1,"CACNA1B"]
["KEGG:04970","Salivary secretion",0.45246294077275701,1,"PLCB1"]
["GO:0002696","positive regulation of leukocyte activation",0.45520448258135299,1,"IL1RL1;TICAM1"]
["GO:0006874","cellular calcium ion homeostasis",0.45520448258135299,1,"CHRNA7;PIK3CB"]
["GO:0005102","receptor binding",0.455510015457953,1,"DBI;ESR2;FLNA;BAZ1B;TRIP12;NRXN1;SHANK2;ANKS1B"]
["GO:0009593","detection of chemical stimulus",0.456166491271355,1,"SOD2"]
["GO:0022626","cytosolic ribosome",0.456166491271355,1,"RPL19"]
["GO:0016410","N-acyltransferase activity",0.456166491271355,1,"KAT2B"]
["KEGG:03015","mRNA surveillance pathway",0.456166491271355,1,"MSI2"]
["GO:0050900","leukocyte migration",0.45745238683376399,1,"PIK3CB;PLCB1"]
["GO:0016746","transferase activity, transferring acyl groups",0.45745238683376399,1,"DBT;KAT2B"]
["GO:0006641","triglyceride metabolic process",0.45984522343938899,1,"SREBF1"]
["GO:0031647","regulation of protein stability",0.45984522343938899,1,"FLNA"]
["GO:0032507","maintenance of protein location in cell",0.45984522343938899,1,"FLNA"]
["GO:0045834","positive regulation of lipid metabolic process",0.45984522343938899,1,"SREBF1"]
["GO:0005923","tight junction",0.45984522343938899,1,"PARD3"]
["GO:0070160","occluding junction",0.45984522343938899,1,"PARD3"]
["KEGG:03010","Ribosome",0.45984522343938899,1,"RPL19"]
["GO:0051270","regulation of cellular component movement",0.46042709612830601,1,"ABL1;ETS1;PLCB1"]
["GO:0003924","GTPase activity",0.46193238196188502,1,"RAB5A;RAC3"]
["GO:0000041","transition metal ion transport",0.463499302031536,1,"STEAP3"]
["GO:0032355","response to estradiol stimulus",0.463499302031536,1,"ETS1"]
["REACT:1227","REACT: Viral mRNA Translation",0.463499302031536,1,"RPL19"]
["KEGG:05032","Morphine addiction",0.463499302031536,1,"CACNA1B"]
["GO:2000113","negative regulation of cellular macromolecule biosynthetic process",0.46442522307921402,1,"ESR2;RFX3;SKI;SMARCA2;PLCB1;EHMT1"]
["GO:0006415","translational termination",0.46712889071910701,1,"RPL19"]
["GO:0007163","establishment or maintenance of cell polarity",0.46712889071910701,1,"PARD3"]
["GO:0043112","receptor metabolic process",0.46712889071910701,1,"RAB5A"]
["GO:0050671","positive regulation of lymphocyte proliferation",0.46712889071910701,1,"TICAM1"]
["REACT:1016","REACT: Signaling by ERBB4",0.46712889071910701,1,"MAPK3"]
["REACT:456","REACT: Generic Transcription Pathway",0.467408775080768,1,"ESR2;KAT2B;SKI"]
["GO:0001654","eye development",0.46861238117164999,1,"MAX;SKI"]
["GO:0016358","dendrite development",0.47073415209710601,1,"SYNGAP1"]
["GO:0030902","hindbrain development",0.47073415209710601,1,"CBS"]
["GO:0032946","positive regulation of mononuclear cell proliferation",0.47073415209710601,1,"TICAM1"]
["GO:0045471","response to ethanol",0.47073415209710601,1,"SOD2"]
["GO:0042470","melanosome",0.47073415209710601,1,"RAB5A"]
["GO:0048770","pigment granule",0.47073415209710601,1,"RAB5A"]
["GO:0004497","monooxygenase activity",0.47073415209710601,1,"CYP7B1"]
["REACT:213","REACT: Cell surface interactions at the vascular wall",0.47073415209710601,1,"PIK3CB"]
["REACT:389","REACT: Formation of a pool of free 40S subunits",0.47073415209710601,1,"RPL19"]
["REACT:588","REACT: L1CAM interactions",0.47073415209710601,1,"MAPK3"]
["GO:0040012","regulation of locomotion",0.470885086374638,1,"ABL1;ETS1;PLCB1"]
["GO:0009888","tissue development",0.47098714546603099,1,"BNC1;CBS;ESR2;MAPK3;SKI;CYP7B1;ZEB2;PLCB1"]
["GO:0009615","response to virus",0.47303870872970699,1,"IKBKG;TICAM1"]
["GO:0050867","positive regulation of cell activation",0.47303870872970699,1,"IL1RL1;TICAM1"]
["GO:0008652","cellular amino acid biosynthetic process",0.47431524769123801,1,"CBS"]
["GO:0050731","positive regulation of peptidyl-tyrosine phosphorylation",0.47431524769123801,1,"TNK2"]
["GO:0071346","cellular response to interferon-gamma",0.47431524769123801,1,"CAMK2G"]
["GO:0007548","sex differentiation",0.47524368650396398,1,"ESR2;UBE3A"]
["GO:0051051","negative regulation of transport",0.47524368650396398,1,"FLNA;MAPK7"]
["GO:0055074","calcium ion homeostasis",0.47524368650396398,1,"CHRNA7;PIK3CB"]
["GO:0022904","respiratory electron transport chain",0.47787233796487599,1,"SOD2"]
["GO:0030509","BMP signaling pathway",0.47787233796487599,1,"SKI"]
["GO:0042157","lipoprotein metabolic process",0.47787233796487599,1,"ABCA1"]
["GO:0070665","positive regulation of leukocyte proliferation",0.47787233796487599,1,"TICAM1"]
["GO:0000776","kinetochore",0.47787233796487599,1,"KAT2B"]
["GO:0044283","small molecule biosynthetic process",0.48125383167901697,1,"CBS;PRKAB2;CYP7B1"]
["GO:0007259","JAK-STAT cascade",0.48140558232597902,1,"MAPK3"]
["GO:0032787","monocarboxylic acid metabolic process",0.48468946205687902,1,"PRKAB2;MAPK3;CYP7B1"]
["GO:0009749","response to glucose stimulus",0.484915139133968,1,"PPP3CB"]
["GO:0030326","embryonic limb morphogenesis",0.484915139133968,1,"SKI"]
["GO:0035113","embryonic appendage morphogenesis",0.484915139133968,1,"SKI"]
["GO:0042089","cytokine biosynthetic process",0.484915139133968,1,"TICAM1"]
["REACT:915","REACT: Regulation of Insulin Secretion",0.484915139133968,1,"PLCB1"]
["GO:0072503","cellular divalent inorganic cation homeostasis",0.48618565638879901,1,"CHRNA7;PIK3CB"]
["GO:0030336","negative regulation of cell migration",0.48840116570656,1,"PLCB1"]
["GO:0042471","ear morphogenesis",0.48840116570656,1,"ATOH1"]
["REACT:815","REACT: Potassium Channels",0.48840116570656,1,"KCNH8"]
["GO:0006302","double-strand break repair",0.49186381832654802,1,"BAZ1B"]
["GO:0006639","acylglycerol metabolic process",0.49186381832654802,1,"SREBF1"]
["GO:0009108","coenzyme biosynthetic process",0.49186381832654802,1,"DBT"]
["GO:0033189","response to vitamin A",0.49186381832654802,1,"ABCA1"]
["GO:0042107","cytokine metabolic process",0.49186381832654802,1,"TICAM1"]
["GO:0050808","synapse organization",0.49186381832654802,1,"NRXN1"]
["GO:0008238","exopeptidase activity",0.49186381832654802,1,"DPP6"]
["REACT:321","REACT: Downstream signaling of activated FGFR",0.49186381832654802,1,"MAPK3"]
["GO:0014706","striated muscle tissue development",0.49268360834090802,1,"SKI;PLCB1"]
["GO:0006638","neutral lipid metabolic process",0.49530325224855298,1,"SREBF1"]
["GO:0014075","response to amine stimulus",0.49530325224855298,1,"PPP3CB"]
["GO:0043433","negative regulation of sequence-specific DNA binding transcription factor activity",0.49530325224855298,1,"FLNA"]
["GO:0051651","maintenance of location in cell",0.49530325224855298,1,"FLNA"]
["GO:0090257","regulation of muscle system process",0.49530325224855298,1,"CAMK2G"]
["GO:2000146","negative regulation of cell motility",0.49530325224855298,1,"PLCB1"]
["REACT:873","REACT: RNA Polymerase II Transcription",0.49530325224855298,1,"TBP"]
["KEGG:04972","Pancreatic secretion",0.49530325224855298,1,"PLCB1"]
["GO:0010558","negative regulation of macromolecule biosynthetic process",0.49757976665320303,1,"ESR2;RFX3;SKI;SMARCA2;PLCB1;EHMT1"]
["GO:0001508","regulation of action potential",0.49871962170571799,1,"SKI"]
["GO:0009746","response to hexose stimulus",0.49871962170571799,1,"PPP3CB"]
["GO:0051607","defense response to virus",0.49871962170571799,1,"TICAM1"]
["REACT:1015","REACT: Signaling by ERBB2",0.49871962170571799,1,"MAPK3"]
["GO:0009101","glycoprotein biosynthetic process",0.499130374025688,1,"LARGE;PLCB1"]
["GO:0006865","amino acid transport",0.50548377909061104,1,"PRKAB2"]
["GO:0045185","maintenance of protein location",0.50548377909061104,1,"FLNA"]
["GO:0048771","tissue remodeling",0.50548377909061104,1,"CBS"]
["GO:0050708","regulation of protein secretion",0.50548377909061104,1,"IL1RL1"]
["GO:0005249","voltage-gated potassium channel activity",0.50548377909061104,1,"KCNH8"]
["REACT:3","REACT: 3' -UTR-mediated translational regulation",0.50548377909061104,1,"RPL19"]
["REACT:587","REACT: L13a-mediated translational silencing of Ceruloplasmin expression",0.50548377909061104,1,"RPL19"]
["GO:0072507","divalent inorganic cation homeostasis",0.5055253805969,1,"CHRNA7;PIK3CB"]
["GO:0030529","ribonucleoprotein complex",0.50733173921199604,1,"RPL19;SNRPN;SYNCRIP;MSI2"]
["GO:0006414","translational elongation",0.50883187043693401,1,"RPL19"]
["GO:0006614","SRP-dependent cotranslational protein targeting to membrane",0.50883187043693401,1,"RPL19"]
["GO:0004222","metalloendopeptidase activity",0.50883187043693401,1,"PMPCB"]
["GO:0008081","phosphoric diester hydrolase activity",0.50883187043693401,1,"PLCB1"]
["GO:0019887","protein kinase regulator activity",0.50883187043693401,1,"KAT2B"]
["REACT:443","REACT: GTP hydrolysis and joining of the 60S ribosomal subunit",0.50883187043693401,1,"RPL19"]
["GO:0071363","cellular response to growth factor stimulus",0.50975969983464298,1,"MAPK3;MAPK7"]
["GO:0006665","sphingolipid metabolic process",0.51215750416870998,1,"LARGE"]
["GO:0048592","eye morphogenesis",0.51215750416870998,1,"SKI"]
["REACT:718","REACT: Nonsense Mediated Decay Enhanced by the Exon Junction Complex",0.51215750416870998,1,"RPL19"]
["REACT:720","REACT: Nonsense-Mediated Decay",0.51215750416870998,1,"RPL19"]
["GO:0060537","muscle tissue development",0.51397063192793002,1,"SKI;PLCB1"]
["GO:0006613","cotranslational protein targeting to membrane",0.51546082951068894,1,"RPL19"]
["GO:0042098","T cell proliferation",0.51546082951068894,1,"PPP3CB"]
["GO:0045047","protein targeting to ER",0.51546082951068894,1,"RPL19"]
["GO:0072599","establishment of protein localization in endoplasmic reticulum",0.51546082951068894,1,"RPL19"]
["GO:0043296","apical junction complex",0.51546082951068894,1,"PARD3"]
["GO:0004620","phospholipase activity",0.51546082951068894,1,"PLCB1"]
["GO:0005789","endoplasmic reticulum membrane",0.51792903947662705,1,"CAMK2G;PCYT1A;SREBF1;CYP7B1;ARHGAP32"]
["GO:0045177","apical part of cell",0.51815803815906203,1,"PRKAB2;PARD3"]
["GO:0007586","digestion",0.51874199470544602,1,"GALR1"]
["GO:0051271","negative regulation of cellular component movement",0.51874199470544602,1,"PLCB1"]
["GO:0004725","protein tyrosine phosphatase activity",0.51874199470544602,1,"PTPRD"]
["REACT:279","REACT: DNA Repair",0.51874199470544602,1,"ERCC6"]
["REACT:532","REACT: Influenza Viral RNA Transcription and Replication",0.51874199470544602,1,"RPL19"]
["REACT:591","REACT: Late Phase of HIV Life Cycle",0.51874199470544602,1,"TBP"]
["GO:0007202","activation of phospholipase C activity",0.52200114701978195,1,"NTSR2"]
["REACT:996","REACT: SRP-dependent cotranslational protein targeting to membrane",0.52200114701978195,1,"RPL19"]
["REACT:1013","REACT: Signaling by EGFR",0.52200114701978195,1,"MAPK3"]
["GO:0010741","negative regulation of intracellular protein kinase cascade",0.52523843275108695,1,"IL1RL1"]
["GO:0034341","response to interferon-gamma",0.52523843275108695,1,"CAMK2G"]
["GO:0005741","mitochondrial outer membrane",0.52523843275108695,1,"SYNJ2"]
["GO:0003012","muscle system process",0.52646175706624898,1,"CAMK2G;DTNA"]
["GO:0035239","tube morphogenesis",0.52646175706624898,1,"SKI;ZEB2"]
["GO:0010927","cellular component assembly involved in morphogenesis",0.52845399723365705,1,"RFX3"]
["GO:0050679","positive regulation of epithelial cell proliferation",0.52845399723365705,1,"CYP7B1"]
["GO:0016327","apicolateral plasma membrane",0.52845399723365705,1,"PARD3"]
["GO:0030017","sarcomere",0.52845399723365705,1,"KAT2B"]
["REACT:1014","REACT: Signaling by EGFR in Cancer",0.52845399723365705,1,"MAPK3"]
["GO:0032403","protein complex binding",0.52852278779879103,1,"ERCC6;MAX"]
["GO:0014031","mesenchymal cell development",0.531647984844975,1,"ZEB2"]
["GO:0060828","regulation of canonical Wnt receptor signaling pathway",0.531647984844975,1,"CSNK1D"]
["REACT:201","REACT: Cap-dependent Translation Initiation",0.531647984844975,1,"RPL19"]
["REACT:354","REACT: Eukaryotic Translation Initiation",0.531647984844975,1,"RPL19"]
["GO:0006643","membrane lipid metabolic process",0.53482053901195303,1,"LARGE"]
["REACT:1017","REACT: Signaling by FGFR",0.53482053901195303,1,"MAPK3"]
["GO:0043414","macromolecule methylation",0.53797180221712704,1,"EHMT1"]
["GO:0042175","nuclear outer membrane-endoplasmic reticulum membrane network",0.53803734808025006,1,"CAMK2G;PCYT1A;SREBF1;CYP7B1;ARHGAP32"]
["GO:0008092","cytoskeletal protein binding",0.53986901820568201,1,"ABL1;FLNA;CYFIP1;TUBGCP5"]
["GO:0010863","positive regulation of phospholipase C activity",0.54110191600481705,1,"NTSR2"]
["GO:0040013","negative regulation of locomotion",0.54110191600481705,1,"PLCB1"]
["GO:0045216","cell-cell junction organization",0.54110191600481705,1,"PARD3"]
["REACT:306","REACT: Disease",0.54176671103071805,1,"MAPK3;PSMB1;PSMC2;RPL19;TBP"]
["GO:0035107","appendage morphogenesis",0.54421102098724505,1,"SKI"]
["GO:0035108","limb morphogenesis",0.54421102098724505,1,"SKI"]
["GO:0005792","microsome",0.54479440548779801,1,"CYP7B1;SYNCRIP"]
["GO:0015075","ion transmembrane transporter activity",0.54548258134193695,1,"ABCA1;CACNA1B;CHRNA7;GRID2;KCNH8"]
["GO:0070972","protein localization in endoplasmic reticulum",0.54729925685061598,1,"RPL19"]
["GO:0070848","response to growth factor stimulus",0.54880170603080802,1,"MAPK3;MAPK7"]
["GO:0005925","focal adhesion",0.550366762361159,1,"MAPK3"]
["GO:0000184","nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",0.55341367537112496,1,"RPL19"]
["GO:0050730","regulation of peptidyl-tyrosine phosphorylation",0.55341367537112496,1,"TNK2"]
["GO:0030133","transport vesicle",0.55341367537112496,1,"SREBF1"]
["REACT:1032","REACT: Signaling by NOTCH",0.55341367537112496,1,"KAT2B"]
["GO:0042598","vesicular fraction",0.55476687097820998,1,"CYP7B1;SYNCRIP"]
["GO:0002263","cell activation involved in immune response",0.55644013282475002,1,"TICAM1"]
["GO:0002366","leukocyte activation involved in immune response",0.55644013282475002,1,"TICAM1"]
["GO:0007369","gastrulation",0.55644013282475002,1,"MAPK7"]
["GO:0010001","glial cell differentiation",0.55644013282475002,1,"SKI"]
["GO:0007179","transforming growth factor beta receptor signaling pathway",0.55944627076418196,1,"SKI"]
["GO:0007281","germ cell development",0.55944627076418196,1,"TSSK2"]
["GO:0019207","kinase regulator activity",0.55944627076418196,1,"KAT2B"]
["GO:0006662","glycerol ether metabolic process",0.562432224335363,1,"SREBF1"]
["GO:0008217","regulation of blood pressure",0.562432224335363,1,"SOD2"]
["GO:0048762","mesenchymal cell differentiation",0.562432224335363,1,"ZEB2"]
["GO:0050795","regulation of behavior",0.562432224335363,1,"NRXN1"]
["GO:0001649","osteoblast differentiation",0.56539812779387799,1,"SKI"]
["GO:0010518","positive regulation of phospholipase activity",0.56539812779387799,1,"NTSR2"]
["GO:0048839","inner ear development",0.56539812779387799,1,"ATOH1"]
["GO:0005924","cell-substrate adherens junction",0.56539812779387799,1,"MAPK3"]
["GO:0034728","nucleosome organization",0.56834411451076405,1,"BAZ1B"]
["GO:0044449","contractile fiber part",0.56834411451076405,1,"KAT2B"]
["GO:0016298","lipase activity",0.57127031697828501,1,"PLCB1"]
["GO:0032259","methylation",0.57417686681566205,1,"EHMT1"]
["REACT:484","REACT: HIV Life Cycle",0.57417686681566205,1,"TBP"]
["GO:0006631","fatty acid metabolic process",0.57616583837061397,1,"PRKAB2;MAPK3"]
["GO:0008194","UDP-glycosyltransferase activity",0.57706389477477504,1,"LARGE"]
["GO:0018904","organic ether metabolic process",0.57993153074582304,1,"SREBF1"]
["GO:0032103","positive regulation of response to external stimulus",0.57993153074582304,1,"IL1RL1"]
["GO:0048736","appendage development",0.57993153074582304,1,"SKI"]
["GO:0060173","limb development",0.57993153074582304,1,"SKI"]
["GO:0030055","cell-substrate junction",0.57993153074582304,1,"MAPK3"]
["GO:0030674","protein binding, bridging",0.57993153074582304,1,"CRKL"]
["REACT:1018","REACT: Signaling by FGFR in disease",0.57993153074582304,1,"MAPK3"]
["GO:0008015","blood circulation",0.58187210829847502,1,"CBS;SOD2"]
["GO:0006399","tRNA metabolic process",0.58277990376294597,1,"WDR4"]
["GO:0010517","regulation of phospholipase activity",0.58277990376294597,1,"NTSR2"]
["GO:0042277","peptide binding",0.58277990376294597,1,"GALR1"]
["GO:0031968","organelle outer membrane",0.58560914200981595,1,"SYNJ2"]
["GO:0044455","mitochondrial membrane part",0.58560914200981595,1,"SYNJ2"]
["GO:0003013","circulatory system process",0.58564526155242702,1,"CBS;SOD2"]
["GO:0009100","glycoprotein metabolic process",0.58752252101838098,1,"LARGE;PLCB1"]
["GO:0007018","microtubule-based movement",0.58841937282518897,1,"RFX3"]
["GO:0030198","extracellular matrix organization",0.58841937282518897,1,"ETS1"]
["GO:0043062","extracellular structure organization",0.58841937282518897,1,"ETS1"]
["GO:0060193","positive regulation of lipase activity",0.58841937282518897,1,"NTSR2"]
["GO:0030016","myofibril",0.58841937282518897,1,"KAT2B"]
["GO:0044391","ribosomal subunit",0.58841937282518897,1,"RPL19"]
["KEGG:05012","Parkinson's disease",0.58841937282518897,1,"PARK2"]
["GO:0044282","small molecule catabolic process",0.589393565717516,1,"CBS;DBT"]
["GO:0009309","amine biosynthetic process",0.59121072270841801,1,"CBS"]
["GO:0030662","coated vesicle membrane",0.59121072270841801,1,"SREBF1"]
["GO:0006633","fatty acid biosynthetic process",0.59398331732493603,1,"PRKAB2"]
["GO:0022900","electron transport chain",0.59398331732493603,1,"SOD2"]
["GO:0050670","regulation of lymphocyte proliferation",0.59398331732493603,1,"TICAM1"]
["GO:0005267","potassium channel activity",0.59398331732493603,1,"KCNH8"]
["REACT:616","REACT: Membrane Trafficking",0.59398331732493603,1,"SNX9"]
["GO:0032944","regulation of mononuclear cell proliferation",0.59673728151170202,1,"TICAM1"]
["GO:0016607","nuclear speck",0.59673728151170202,1,"PLCB1"]
["GO:0007059","chromosome segregation",0.59947273928260703,1,"SMC2"]
["GO:0008543","fibroblast growth factor receptor signaling pathway",0.59947273928260703,1,"MAPK3"]
["GO:0090092","regulation of transmembrane receptor protein serine/threonine kinase signaling pathway",0.59947273928260703,1,"SKI"]
["GO:0019867","outer membrane",0.59947273928260703,1,"SYNJ2"]
["GO:0055085","transmembrane transport",0.60193237198086003,1,"CACNA1B;FLNA;PRKAB2;MAPK7;STEAP3;KCNH8"]
["GO:0006333","chromatin assembly or disassembly",0.60218981383384995,1,"BAZ1B"]
["GO:0051188","cofactor biosynthetic process",0.60218981383384995,1,"DBT"]
["GO:0015631","tubulin binding",0.60218981383384995,1,"TUBGCP5"]
["GO:0019842","vitamin binding",0.60218981383384995,1,"CBS"]
["GO:0048545","response to steroid hormone stimulus",0.60413800238837601,1,"ESR2;ETS1"]
["GO:0030278","regulation of ossification",0.60488862754928097,1,"SKI"]
["NCI:154","NCI:P53DOWNSTREAMPATHWAY",0.60488862754928097,1,"STEAP3"]
["GO:0006575","cellular modified amino acid metabolic process",0.60756930200570303,1,"SOD2"]
["GO:0006694","steroid biosynthetic process",0.60756930200570303,1,"CYP7B1"]
["GO:0045333","cellular respiration",0.60756930200570303,1,"SOD2"]
["GO:0070663","regulation of leukocyte proliferation",0.60756930200570303,1,"TICAM1"]
["GO:0060090","binding, bridging",0.60756930200570303,1,"CRKL"]
["GO:0007276","gamete generation",0.60772388927295395,1,"TBP;TSSK2;ZSCAN2"]
["GO:0015980","energy derivation by oxidation of organic compounds",0.60956449465062801,1,"PRKAB2;SOD2"]
["GO:2000241","regulation of reproductive process",0.610231957978143,1,"PLCB1"]
["GO:0000151","ubiquitin ligase complex",0.610231957978143,1,"CUL2"]
["REACT:163","REACT: Biological oxidations",0.610231957978143,1,"CYP7B1"]
["GO:0007156","homophilic cell adhesion",0.61287671544509403,1,"PIK3CB"]
["GO:0042063","gliogenesis",0.61287671544509403,1,"SKI"]
["GO:0043292","contractile fiber",0.61287671544509403,1,"KAT2B"]
["REACT:233","REACT: Class A/1 (Rhodopsin-like receptors)",0.61315105153637195,1,"GALR1;NTSR2"]
["GO:0051241","negative regulation of multicellular organismal process",0.61493500254454803,1,"CHRNA7;IL1RL1"]
["GO:0031966","mitochondrial membrane",0.61791624640584697,1,"SOD2;SYNJ2;PMPCB"]
["GO:0030162","regulation of proteolysis",0.61811301082498205,1,"CSNK1D"]
["GO:0060485","mesenchyme development",0.61811301082498205,1,"ZEB2"]
["GO:0051640","organelle localization",0.62070478475887303,1,"SYNJ2"]
["GO:0031225","anchored to membrane",0.62070478475887303,1,"LSAMP"]
["GO:0034703","cation channel complex",0.62070478475887303,1,"CACNA1B"]
["GO:0006805","xenobiotic metabolic process",0.623279132239419,1,"CYP7B1"]
["REACT:531","REACT: Influenza Life Cycle",0.623279132239419,1,"RPL19"]
["GO:0009410","response to xenobiotic stimulus",0.62583616933979802,1,"CYP7B1"]
["GO:0071466","cellular response to xenobiotic stimulus",0.62583616933979802,1,"CYP7B1"]
["GO:0071824","protein-DNA complex subunit organization",0.62583616933979802,1,"BAZ1B"]
["GO:0044432","endoplasmic reticulum part",0.62677811255052496,1,"CAMK2G;PCYT1A;SREBF1;CYP7B1;ARHGAP32"]
["REACT:1172","REACT: Translation",0.62837601136737198,1,"RPL19"]
["GO:0002694","regulation of leukocyte activation",0.63071114798236705,1,"IL1RL1;TICAM1"]
["GO:0044344","cellular response to fibroblast growth factor stimulus",0.63089877286868401,1,"MAPK3"]
["GO:0071774","response to fibroblast growth factor stimulus",0.63089877286868401,1,"MAPK3"]
["GO:0006396","RNA processing",0.63175794242207595,1,"SNRPN;WTAP;SYNCRIP;WDR4"]
["GO:0043583","ear development",0.63340456763443898,1,"ATOH1"]
["GO:0015079","potassium ion transmembrane transporter activity",0.63589350870443295,1,"KCNH8"]
["REACT:530","REACT: Influenza Infection",0.63589350870443295,1,"RPL19"]
["GO:0006323","DNA packaging",0.64082127819124002,1,"SMC2"]
["GO:0019080","viral genome expression",0.64082127819124002,1,"RPL19"]
["GO:0019083","viral transcription",0.64082127819124002,1,"RPL19"]
["GO:0030217","T cell differentiation",0.64082127819124002,1,"PPP3CB"]
["GO:0032535","regulation of cellular component size",0.64082127819124002,1,"LIMK1"]
["GO:0042113","B cell activation",0.64082127819124002,1,"TICAM1"]
["GO:0008509","anion transmembrane transporter activity",0.64082127819124002,1,"ABCA1"]
["GO:0006413","translational initiation",0.64326032897714702,1,"RPL19"]
["GO:0043624","cellular protein complex disassembly",0.64326032897714702,1,"RPL19"]
["GO:0043627","response to estrogen stimulus",0.64326032897714702,1,"ETS1"]
["GO:0060191","regulation of lipase activity",0.64568297081514203,1,"NTSR2"]
["GO:0043235","receptor complex",0.64808931306349304,1,"CHRNA7"]
["GO:0016829","lyase activity",0.64808931306349304,1,"CBS"]
["KEGG:04145","Phagosome",0.64808931306349304,1,"RAB5A"]
["GO:0005740","mitochondrial envelope",0.648790050709384,1,"SOD2;SYNJ2;PMPCB"]
["REACT:1027","REACT: Signaling by GPCR",0.65014519722575903,1,"GALR1;MAPK3;MAPK7;NTSR2;PLCB1;PPP3CB"]
["GO:0003007","heart morphogenesis",0.65047946435854298,1,"BAZ1B"]
["GO:0006820","anion transport",0.65047946435854298,1,"ABCA1"]
["KEGG:04630","Jak-STAT signaling pathway",0.65047946435854298,1,"PIK3CB"]
["GO:0005743","mitochondrial inner membrane",0.654257043087626,1,"SOD2;PMPCB"]
["GO:0043241","protein complex disassembly",0.65521162505274599,1,"RPL19"]
["KEGG:03013","RNA transport",0.65521162505274599,1,"CYFIP1"]
["GO:0071702","organic substance transport",0.65690170446016305,1,"ABCA1;PARK2;PRKAB2"]
["GO:0030334","regulation of cell migration",0.65752257944623704,1,"ETS1;PLCB1"]
["GO:0002449","lymphocyte mediated immunity",0.66219110886338794,1,"PPP3CB"]
["GO:0031253","cell projection membrane",0.66219110886338794,1,"SYNJ2"]
["GO:0016705","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",0.66219110886338794,1,"CYP7B1"]
["GO:0007173","epidermal growth factor receptor signaling pathway",0.66448635596470995,1,"MAPK3"]
["GO:0043254","regulation of protein complex assembly",0.66448635596470995,1,"SNX9"]
["GO:0060541","respiratory system development",0.66448635596470995,1,"SKI"]
["GO:0003735","structural constituent of ribosome",0.66448635596470995,1,"RPL19"]
["GO:0045321","leukocyte activation",0.66488032925309903,1,"PPP3CB;IL1RL1;TICAM1"]
["GO:0006112","energy reserve metabolic process",0.66676615274579698,1,"PRKAB2"]
["GO:0050865","regulation of cell activation",0.66876034370155801,1,"IL1RL1;TICAM1"]
["GO:0051235","maintenance of location",0.66903060223495003,1,"FLNA"]
["GO:0022891","substrate-specific transmembrane transporter activity",0.67902319888100204,1,"ABCA1;CACNA1B;CHRNA7;GRID2;KCNH8"]
["GO:0000956","nuclear-transcribed mRNA catabolic process",0.680126198903651,1,"RPL19"]
["GO:0048193","Golgi vesicle transport",0.68230069043588104,1,"RER1"]
["GO:0003714","transcription corepressor activity",0.68230069043588104,1,"SKI"]
["GO:0008236","serine-type peptidase activity",0.692955419058783,1,"DPP6"]
["GO:0009897","external side of plasma membrane",0.69504349393870601,1,"IL1RL1"]
["GO:0019866","organelle inner membrane",0.696306132150179,1,"SOD2;PMPCB"]
["GO:0051052","regulation of DNA metabolic process",0.697117500558458,1,"CDK2"]
["GO:0017171","serine hydrolase activity",0.697117500558458,1,"DPP6"]
["GO:0015672","monovalent inorganic cation transport",0.69924839471599798,1,"CDK2;KCNH8"]
["GO:0006402","mRNA catabolic process",0.70122368397953205,1,"RPL19"]
["GO:0044429","mitochondrial part",0.70176309130368597,1,"DBT;SOD2;SYNJ2;PMPCB"]
["GO:0051606","detection of stimulus",0.70325604671406405,1,"SOD2"]
["KEGG:05034","Alcoholism",0.70325604671406405,1,"MAPK3"]
["GO:0046942","carboxylic acid transport",0.70527471306294798,1,"PRKAB2"]
["GO:0008237","metallopeptidase activity",0.70527471306294798,1,"PMPCB"]
["KEGG:05202","Transcriptional misregulation in cancer",0.70527471306294798,1,"MAX"]
["GO:0002252","immune effector process",0.70650203114884402,1,"PPP3CB;TICAM1"]
["GO:0006417","regulation of translation",0.70927132174695096,1,"MAPK3"]
["GO:0015849","organic acid transport",0.70927132174695096,1,"PRKAB2"]
["GO:0048562","embryonic organ morphogenesis",0.70927132174695096,1,"ATOH1"]
["GO:0071103","DNA conformation change",0.71321423429506203,1,"SMC2"]
["GO:0006730","one-carbon metabolic process",0.71516577823619898,1,"EHMT1"]
["GO:0002697","regulation of immune effector process",0.71710416542240496,1,"PPP3CB"]
["GO:0072594","establishment of protein localization to organelle",0.71710416542240496,1,"RPL19"]
["GO:0016758","transferase activity, transferring hexosyl groups",0.71710416542240496,1,"LARGE"]
["GO:0045165","cell fate commitment",0.71902948372159103,1,"ATOH1"]
["GO:0005882","intermediate filament",0.71902948372159103,1,"DLGAP2"]
["GO:0004175","endopeptidase activity",0.72332373863603905,1,"PSMB1;PMPCB"]
["GO:0070011","peptidase activity, acting on L-amino acid peptides",0.72392374232333501,1,"DPP6;PSMB1;PMPCB"]
["GO:0005525","GTP binding",0.72468861844166699,1,"RAB5A;RAC3"]
["GO:0008324","cation transmembrane transporter activity",0.72846318605771898,1,"CACNA1B;CHRNA7;KCNH8"]
["GO:0035295","tube development",0.73276029346362304,1,"SKI;ZEB2"]
["GO:0007568","aging",0.73578346196473798,1,"SOD2"]
["GO:0030335","positive regulation of cell migration",0.73578346196473798,1,"ETS1"]
["GO:0006732","coenzyme metabolic process",0.73758279811352701,1,"DBT"]
["GO:0019001","guanyl nucleotide binding",0.74063244101345105,1,"RAB5A;RAC3"]
["GO:0032561","guanyl ribonucleotide binding",0.74063244101345105,1,"RAB5A;RAC3"]
["GO:2000147","positive regulation of cell motility",0.74114513191406906,1,"ETS1"]
["GO:0006486","protein glycosylation",0.74290829130583103,1,"LARGE"]
["GO:0043413","macromolecule glycosylation",0.74290829130583103,1,"LARGE"]
["GO:0016324","apical plasma membrane",0.74290829130583103,1,"PRKAB2"]
["REACT:408","REACT: G alpha (i) signalling events",0.74290829130583103,1,"GALR1"]
["GO:0006397","mRNA processing",0.74321265833926498,1,"WTAP;SYNCRIP"]
["GO:0008233","peptidase activity",0.74497387761973399,1,"DPP6;PSMB1;PMPCB"]
["GO:0002443","leukocyte mediated immunity",0.74639899541469301,1,"PPP3CB"]
["GO:0030098","lymphocyte differentiation",0.74639899541469301,1,"PPP3CB"]
["GO:0070085","glycosylation",0.74639899541469301,1,"LARGE"]
["GO:0000377","RNA splicing, via transesterification reactions with bulged adenosine as nucleophile",0.74812669868036397,1,"SYNCRIP"]
["GO:0000398","nuclear mRNA splicing, via spliceosome",0.74812669868036397,1,"SYNCRIP"]
["GO:0006310","DNA recombination",0.75154720007627795,1,"SMC2"]
["GO:0034470","ncRNA processing",0.75154720007627795,1,"WDR4"]
["GO:0040017","positive regulation of locomotion",0.75324015362603502,1,"ETS1"]
["GO:0051272","positive regulation of cellular component movement",0.75492167849942804,1,"ETS1"]
["GO:0005840","ribosome",0.75492167849942804,1,"RPL19"]
["GO:0000375","RNA splicing, via transesterification reactions",0.75659185112541105,1,"SYNCRIP"]
["GO:0014070","response to organic cyclic compound",0.75659185112541105,1,"CHRNA7"]
["GO:0007178","transmembrane receptor protein serine/threonine kinase signaling pathway",0.75825074742665799,1,"SKI"]
["GO:0051251","positive regulation of lymphocyte activation",0.75989844282288399,1,"TICAM1"]
["GO:0022857","transmembrane transporter activity",0.76188621810815405,1,"ABCA1;CACNA1B;CHRNA7;GRID2;KCNH8"]
["REACT:437","REACT: GPCR ligand binding",0.76783844190370198,1,"GALR1;NTSR2"]
["GO:0043566","structure-specific DNA binding",0.76955355715305995,1,"ATOH1"]
["GO:0006091","generation of precursor metabolites and energy",0.77937258620241101,1,"PRKAB2;SOD2"]
["GO:0046649","lymphocyte activation",0.787148560680766,1,"PPP3CB;TICAM1"]
["GO:0006725","cellular aromatic compound metabolic process",0.78772465878714004,1,"PARK2"]
["GO:0019058","viral infectious cycle",0.78917322138342705,1,"RPL19"]
["GO:0006936","muscle contraction",0.793460411868537,1,"DTNA"]
["GO:0005198","structural molecule activity",0.79434816792446505,1,"RPL19;BAZ1B;SHANK2"]
["GO:0016042","lipid catabolic process",0.79627044156233695,1,"PLCB1"]
["GO:0022892","substrate-specific transporter activity",0.80054130483450603,1,"ABCA1;CACNA1B;CHRNA7;GRID2;KCNH8"]
["GO:0030141","secretory granule",0.80177737048644704,1,"TSSK2"]
["GO:0043009","chordate embryonic development",0.80198769186608598,1,"SKI;ZEB2"]
["REACT:630","REACT: Metabolism of proteins",0.80403187492564898,1,"PMPCB;RPL19"]
["GO:0009986","cell surface",0.80504700193085499,1,"IL1RL1;NRXN1"]
["GO:0009792","embryo development ending in birth or egg hatching",0.80906144194968899,1,"SKI;ZEB2"]
["GO:0034621","cellular macromolecular complex subunit organization",0.80924125089786603,1,"RPL19;BAZ1B;SNX9"]
["GO:0043025","neuronal cell body",0.81235263782938805,1,"RAC3"]
["GO:0051186","cofactor metabolic process",0.81867631564002996,1,"DBT"]
["GO:0006412","translation",0.82067095469147899,1,"MAPK3;RPL19"]
["GO:0022415","viral reproductive process",0.82478881175693797,1,"RPL19"]
["GO:0008544","epidermis development",0.825986588216305,1,"BNC1"]
["GO:0005509","calcium ion binding",0.82795261587223801,1,"DTNA;PPP3CB;PLCB1"]
["GO:0005911","cell-cell junction",0.82953146164011804,1,"PARD3"]
["GO:0044297","cell body",0.83069711435001803,1,"RAC3"]
["GO:0016757","transferase activity, transferring glycosyl groups",0.83185487039044403,1,"LARGE"]
["GO:0006260","DNA replication",0.83414690408817405,1,"CDK2"]
["GO:0016323","basolateral plasma membrane",0.83752704307308801,1,"MAPK3"]
["GO:0030855","epithelial cell differentiation",0.84300960018502602,1,"ESR2"]
["GO:0046873","metal ion transmembrane transporter activity",0.84621074047158495,1,"KCNH8"]
["GO:0048568","embryonic organ development",0.84830882258957796,1,"ATOH1"]
["GO:0051249","regulation of lymphocyte activation",0.84934720503362604,1,"TICAM1"]
["GO:0005996","monosaccharide metabolic process",0.85838136277027499,1,"LARGE"]
["GO:0016491","oxidoreductase activity",0.85878683084029095,1,"SOD2;CYP7B1;STEAP3"]
["GO:0034660","ncRNA metabolic process",0.85935141553153105,1,"WDR4"]
["GO:0002521","leukocyte differentiation",0.86779090700954498,1,"PPP3CB"]
["GO:0044262","cellular carbohydrate metabolic process",0.87802042769799005,1,"SYNJ2;LARGE"]
["GO:0042110","T cell activation",0.87826790968801205,1,"PPP3CB"]
["GO:0015077","monovalent inorganic cation transmembrane transporter activity",0.88157405837443803,1,"KCNH8"]
["GO:0034220","ion transmembrane transport",0.88945533342661098,1,"CACNA1B"]
["GO:0055114","oxidation-reduction process",0.89067723732251103,1,"PRKAB2;SOD2"]
["KEGG:01100","Metabolic pathways",0.90062817020236896,1,"CBS;DBT;PCYT1A;SYNJ2;PLCB1"]
["GO:0005215","transporter activity",0.91370103325047503,1,"ABCA1;CACNA1B;CHRNA7;GRID2;KCNH8"]
["GO:0022890","inorganic cation transmembrane transporter activity",0.91435409243767896,1,"KCNH8"]
["REACT:436","REACT: GPCR downstream signaling",0.93559408296858204,1,"GALR1;NTSR2;PLCB1"]
["KEGG:04740","Olfactory transduction",0.93725852591115,1,"CAMK2G"]
["REACT:1180","REACT: Transmembrane transport of small molecules",0.94796752322745903,1,"STEAP3"]
["GO:0005975","carbohydrate metabolic process",0.950790558773287,1,"SYNJ2;LARGE"]
["GO:0034622","cellular macromolecular complex assembly",0.96474353901784804,1,"SNX9"]
["GO:0004930","G-protein coupled receptor activity",0.98155266809873798,1,"GALR1;NTSR2"]
["GO:0005615","extracellular space",0.99652031116166395,1,"IL1RL1"]
["GO:0044421","extracellular region part",0.99946552234902297,1,"IL1RL1"]
["GO:0000018","regulation of DNA recombination",1,1]
["GO:0000045","autophagic vacuole assembly",1,1]
["GO:0000060","protein import into nucleus, translocation",1,1]
["GO:0000083","regulation of transcription involved in G1/S phase of mitotic cell cycle",1,1]
["GO:0000188","inactivation of MAPK activity",1,1]
["GO:0000236","mitotic prometaphase",1,1]
["GO:0000245","spliceosome assembly",1,1]
["GO:0000271","polysaccharide biosynthetic process",1,1]
["GO:0000272","polysaccharide catabolic process",1,1]
["GO:0000288","nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay",1,1]
["GO:0000289","nuclear-transcribed mRNA poly(A) tail shortening",1,1]
["GO:0000291","nuclear-transcribed mRNA catabolic process, exonucleolytic",1,1]
["GO:0000301","retrograde transport, vesicle recycling within Golgi",1,1]
["GO:0000380","alternative nuclear mRNA splicing, via spliceosome",1,1]
["GO:0000381","regulation of alternative nuclear mRNA splicing, via spliceosome",1,1]
["GO:0000387","spliceosomal snRNP assembly",1,1]
["GO:0000413","protein peptidyl-prolyl isomerization",1,1]
["GO:0000578","embryonic axis specification",1,1]
["GO:0000718","nucleotide-excision repair, DNA damage removal",1,1]
["GO:0000722","telomere maintenance via recombination",1,1]
["GO:0000723","telomere maintenance",1,1]
["GO:0000724","double-strand break repair via homologous recombination",1,1]
["GO:0000725","recombinational repair",1,1]
["GO:0000726","non-recombinational repair",1,1]
["GO:0000737","DNA catabolic process, endonucleolytic",1,1]
["GO:0000910","cytokinesis",1,1]
["GO:0001502","cartilage condensation",1,1]
["GO:0001516","prostaglandin biosynthetic process",1,1]
["GO:0001522","pseudouridine synthesis",1,1]
["GO:0001523","retinoid metabolic process",1,1]
["GO:0001569","patterning of blood vessels",1,1]
["GO:0001570","vasculogenesis",1,1]
["GO:0001578","microtubule bundle formation",1,1]
["GO:0001656","metanephros development",1,1]
["GO:0001657","ureteric bud development",1,1]
["GO:0001658","branching involved in ureteric bud morphogenesis",1,1]
["GO:0001659","temperature homeostasis",1,1]
["GO:0001662","behavioral fear response",1,1]
["GO:0001701","in utero embryonic development",1,1]
["GO:0001702","gastrulation with mouth forming second",1,1]
["GO:0001704","formation of primary germ layer",1,1]
["GO:0001706","endoderm formation",1,1]
["GO:0001707","mesoderm formation",1,1]
["GO:0001710","mesodermal cell fate commitment",1,1]
["GO:0001736","establishment of planar polarity",1,1]
["GO:0001738","morphogenesis of a polarized epithelium",1,1]
["GO:0001754","eye photoreceptor cell differentiation",1,1]
["GO:0001759","organ induction",1,1]
["GO:0001763","morphogenesis of a branching structure",1,1]
["GO:0001822","kidney development",1,1]
["GO:0001823","mesonephros development",1,1]
["GO:0001824","blastocyst development",1,1]
["GO:0001825","blastocyst formation",1,1]
["GO:0001829","trophectodermal cell differentiation",1,1]
["GO:0001837","epithelial to mesenchymal transition",1,1]
["GO:0001881","receptor recycling",1,1]
["GO:0001885","endothelial cell development",1,1]
["GO:0001890","placenta development",1,1]
["GO:0001892","embryonic placenta development",1,1]
["GO:0001893","maternal placenta development",1,1]
["GO:0001894","tissue homeostasis",1,1]
["GO:0001912","positive regulation of leukocyte mediated cytotoxicity",1,1]
["GO:0001919","regulation of receptor recycling",1,1]
["GO:0001935","endothelial cell proliferation",1,1]
["GO:0001936","regulation of endothelial cell proliferation",1,1]
["GO:0001937","negative regulation of endothelial cell proliferation",1,1]
["GO:0001938","positive regulation of endothelial cell proliferation",1,1]
["GO:0001942","hair follicle development",1,1]
["GO:0001945","lymph vessel development",1,1]
["GO:0001947","heart looping",1,1]
["GO:0001953","negative regulation of cell-matrix adhesion",1,1]
["GO:0001954","positive regulation of cell-matrix adhesion",1,1]
["GO:0001959","regulation of cytokine-mediated signaling pathway",1,1]
["GO:0001960","negative regulation of cytokine-mediated signaling pathway",1,1]
["GO:0001990","regulation of systemic arterial blood pressure by hormone",1,1]
["GO:0002021","response to dietary excess",1,1]
["GO:0002026","regulation of the force of heart contraction",1,1]
["GO:0002027","regulation of heart rate",1,1]
["GO:0002028","regulation of sodium ion transport",1,1]
["GO:0002029","desensitization of G-protein coupled receptor protein signaling pathway",1,1]
["GO:0002040","sprouting angiogenesis",1,1]
["GO:0002042","cell migration involved in sprouting angiogenesis",1,1]
["GO:0002053","positive regulation of mesenchymal cell proliferation",1,1]
["GO:0002062","chondrocyte differentiation",1,1]
["GO:0002065","columnar/cuboidal epithelial cell differentiation",1,1]
["GO:0002076","osteoblast development",1,1]
["GO:0002200","somatic diversification of immune receptors",1,1]
["GO:0002204","somatic recombination of immunoglobulin genes involved in immune response",1,1]
["GO:0002208","somatic diversification of immunoglobulins involved in immune response",1,1]
["GO:0002209","behavioral defense response",1,1]
["GO:0002228","natural killer cell mediated immunity",1,1]
["GO:0002244","hemopoietic progenitor cell differentiation",1,1]
["GO:0002279","mast cell activation involved in immune response",1,1]
["GO:0002285","lymphocyte activation involved in immune response",1,1]
["GO:0002286","T cell activation involved in immune response",1,1]
["GO:0002287","alpha-beta T cell activation involved in immune response",1,1]
["GO:0002292","T cell differentiation involved in immune response",1,1]
["GO:0002293","alpha-beta T cell differentiation involved in immune response",1,1]
["GO:0002294","CD4-positive, alpha-beta T cell differentiation involved in immune response",1,1]
["GO:0002312","B cell activation involved in immune response",1,1]
["GO:0002367","cytokine production involved in immune response",1,1]
["GO:0002377","immunoglobulin production",1,1]
["GO:0002381","immunoglobulin production involved in immunoglobulin mediated immune response",1,1]
["GO:0002437","inflammatory response to antigenic stimulus",1,1]
["GO:0002440","production of molecular mediator of immune response",1,1]
["GO:0002444","myeloid leukocyte mediated immunity",1,1]
["GO:0002446","neutrophil mediated immunity",1,1]
["GO:0002448","mast cell mediated immunity",1,1]
["GO:0002455","humoral immune response mediated by circulating immunoglobulin",1,1]
["GO:0002467","germinal center formation",1,1]
["GO:0002504","antigen processing and presentation of peptide or polysaccharide antigen via MHC class II",1,1]
["GO:0002526","acute inflammatory response",1,1]
["GO:0002532","production of molecular mediator involved in inflammatory response",1,1]
["GO:0002544","chronic inflammatory response",1,1]
["GO:0002548","monocyte chemotaxis",1,1]
["GO:0002562","somatic diversification of immune receptors via germline recombination within a single locus",1,1]
["GO:0002573","myeloid leukocyte differentiation",1,1]
["GO:0002637","regulation of immunoglobulin production",1,1]
["GO:0002673","regulation of acute inflammatory response",1,1]
["GO:0002675","positive regulation of acute inflammatory response",1,1]
["GO:0002687","positive regulation of leukocyte migration",1,1]
["GO:0002688","regulation of leukocyte chemotaxis",1,1]
["GO:0002690","positive regulation of leukocyte chemotaxis",1,1]
["GO:0002695","negative regulation of leukocyte activation",1,1]
["GO:0002699","positive regulation of immune effector process",1,1]
["GO:0002700","regulation of production of molecular mediator of immune response",1,1]
["GO:0002702","positive regulation of production of molecular mediator of immune response",1,1]
["GO:0002705","positive regulation of leukocyte mediated immunity",1,1]
["GO:0002708","positive regulation of lymphocyte mediated immunity",1,1]
["GO:0002711","positive regulation of T cell mediated immunity",1,1]
["GO:0002712","regulation of B cell mediated immunity",1,1]
["GO:0002715","regulation of natural killer cell mediated immunity",1,1]
["GO:0002717","positive regulation of natural killer cell mediated immunity",1,1]
["GO:0002718","regulation of cytokine production involved in immune response",1,1]
["GO:0002720","positive regulation of cytokine production involved in immune response",1,1]
["GO:0002761","regulation of myeloid leukocyte differentiation",1,1]
["GO:0002762","negative regulation of myeloid leukocyte differentiation",1,1]
["GO:0002763","positive regulation of myeloid leukocyte differentiation",1,1]
["GO:0002792","negative regulation of peptide secretion",1,1]
["GO:0002821","positive regulation of adaptive immune response",1,1]
["GO:0002824","positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains",1,1]
["GO:0002828","regulation of type 2 immune response",1,1]
["GO:0002831","regulation of response to biotic stimulus",1,1]
["GO:0002861","regulation of inflammatory response to antigenic stimulus",1,1]
["GO:0002886","regulation of myeloid leukocyte mediated immunity",1,1]
["GO:0002889","regulation of immunoglobulin mediated immune response",1,1]
["GO:0002920","regulation of humoral immune response",1,1]
["GO:0003009","skeletal muscle contraction",1,1]
["GO:0003014","renal system process",1,1]
["GO:0003015","heart process",1,1]
["GO:0003016","respiratory system process",1,1]
["GO:0003071","renal system process involved in regulation of systemic arterial blood pressure",1,1]
["GO:0003081","regulation of systemic arterial blood pressure by renin-angiotensin",1,1]
["GO:0003143","embryonic heart tube morphogenesis",1,1]
["GO:0003151","outflow tract morphogenesis",1,1]
["GO:0003156","regulation of organ formation",1,1]
["GO:0003158","endothelium development",1,1]
["GO:0003170","heart valve development",1,1]
["GO:0003179","heart valve morphogenesis",1,1]
["GO:0003197","endocardial cushion development",1,1]
["GO:0003205","cardiac chamber development",1,1]
["GO:0003206","cardiac chamber morphogenesis",1,1]
["GO:0003208","cardiac ventricle morphogenesis",1,1]
["GO:0003209","cardiac atrium morphogenesis",1,1]
["GO:0003229","ventricular cardiac muscle tissue development",1,1]
["GO:0003230","cardiac atrium development",1,1]
["GO:0003231","cardiac ventricle development",1,1]
["GO:0003279","cardiac septum development",1,1]
["GO:0003281","ventricular septum development",1,1]
["GO:0003300","cardiac muscle hypertrophy",1,1]
["GO:0003338","metanephros morphogenesis",1,1]
["GO:0003382","epithelial cell morphogenesis",1,1]
["GO:0003401","axis elongation",1,1]
["GO:0003407","neural retina development",1,1]
["GO:0005976","polysaccharide metabolic process",1,1]
["GO:0005977","glycogen metabolic process",1,1]
["GO:0005978","glycogen biosynthetic process",1,1]
["GO:0005979","regulation of glycogen biosynthetic process",1,1]
["GO:0005980","glycogen catabolic process",1,1]
["GO:0006000","fructose metabolic process",1,1]
["GO:0006004","fucose metabolic process",1,1]
["GO:0006006","glucose metabolic process",1,1]
["GO:0006007","glucose catabolic process",1,1]
["GO:0006013","mannose metabolic process",1,1]
["GO:0006022","aminoglycan metabolic process",1,1]
["GO:0006023","aminoglycan biosynthetic process",1,1]
["GO:0006024","glycosaminoglycan biosynthetic process",1,1]
["GO:0006026","aminoglycan catabolic process",1,1]
["GO:0006027","glycosaminoglycan catabolic process",1,1]
["GO:0006029","proteoglycan metabolic process",1,1]
["GO:0006063","uronic acid metabolic process",1,1]
["GO:0006071","glycerol metabolic process",1,1]
["GO:0006073","cellular glucan metabolic process",1,1]
["GO:0006081","cellular aldehyde metabolic process",1,1]
["GO:0006084","acetyl-CoA metabolic process",1,1]
["GO:0006085","acetyl-CoA biosynthetic process",1,1]
["GO:0006090","pyruvate metabolic process",1,1]
["GO:0006094","gluconeogenesis",1,1]
["GO:0006096","glycolysis",1,1]
["GO:0006099","tricarboxylic acid cycle",1,1]
["GO:0006103","2-oxoglutarate metabolic process",1,1]
["GO:0006109","regulation of carbohydrate metabolic process",1,1]
["GO:0006110","regulation of glycolysis",1,1]
["GO:0006111","regulation of gluconeogenesis",1,1]
["GO:0006119","oxidative phosphorylation",1,1]
["GO:0006120","mitochondrial electron transport, NADH to ubiquinone",1,1]
["GO:0006144","purine base metabolic process",1,1]
["GO:0006182","cGMP biosynthetic process",1,1]
["GO:0006206","pyrimidine base metabolic process",1,1]
["GO:0006213","pyrimidine nucleoside metabolic process",1,1]
["GO:0006220","pyrimidine nucleotide metabolic process",1,1]
["GO:0006221","pyrimidine nucleotide biosynthetic process",1,1]
["GO:0006261","DNA-dependent DNA replication",1,1]
["GO:0006270","DNA-dependent DNA replication initiation",1,1]
["GO:0006271","DNA strand elongation involved in DNA replication",1,1]
["GO:0006278","RNA-dependent DNA replication",1,1]
["GO:0006282","regulation of DNA repair",1,1]
["GO:0006297","nucleotide-excision repair, DNA gap filling",1,1]
["GO:0006308","DNA catabolic process",1,1]
["GO:0006309","DNA fragmentation involved in apoptotic nuclear change",1,1]
["GO:0006312","mitotic recombination",1,1]
["GO:0006334","nucleosome assembly",1,1]
["GO:0006336","DNA replication-independent nucleosome assembly",1,1]
["GO:0006342","chromatin silencing",1,1]
["GO:0006353","transcription termination, DNA-dependent",1,1]
["GO:0006359","regulation of transcription from RNA polymerase III promoter",1,1]
["GO:0006362","transcription elongation from RNA polymerase I promoter",1,1]
["GO:0006363","termination of RNA polymerase I transcription",1,1]
["GO:0006364","rRNA processing",1,1]
["GO:0006369","termination of RNA polymerase II transcription",1,1]
["GO:0006370","mRNA capping",1,1]
["GO:0006376","mRNA splice site selection",1,1]
["GO:0006378","mRNA polyadenylation",1,1]
["GO:0006385","transcription elongation from RNA polymerase III promoter",1,1]
["GO:0006386","termination of RNA polymerase III transcription",1,1]
["GO:0006403","RNA localization",1,1]
["GO:0006405","RNA export from nucleus",1,1]
["GO:0006406","mRNA export from nucleus",1,1]
["GO:0006418","tRNA aminoacylation for protein translation",1,1]
["GO:0006446","regulation of translational initiation",1,1]
["GO:0006457","protein folding",1,1]
["GO:0006458","'de novo' protein folding",1,1]
["GO:0006471","protein ADP-ribosylation",1,1]
["GO:0006482","protein demethylation",1,1]
["GO:0006487","protein N-linked glycosylation",1,1]
["GO:0006488","dolichol-linked oligosaccharide biosynthetic process",1,1]
["GO:0006493","protein O-linked glycosylation",1,1]
["GO:0006501","C-terminal protein lipidation",1,1]
["GO:0006505","GPI anchor metabolic process",1,1]
["GO:0006506","GPI anchor biosynthetic process",1,1]
["GO:0006509","membrane protein ectodomain proteolysis",1,1]
["GO:0006516","glycoprotein catabolic process",1,1]
["GO:0006536","glutamate metabolic process",1,1]
["GO:0006541","glutamine metabolic process",1,1]
["GO:0006555","methionine metabolic process",1,1]
["GO:0006586","indolalkylamine metabolic process",1,1]
["GO:0006595","polyamine metabolic process",1,1]
["GO:0006611","protein export from nucleus",1,1]
["GO:0006625","protein targeting to peroxisome",1,1]
["GO:0006626","protein targeting to mitochondrion",1,1]
["GO:0006635","fatty acid beta-oxidation",1,1]
["GO:0006636","unsaturated fatty acid biosynthetic process",1,1]
["GO:0006672","ceramide metabolic process",1,1]
["GO:0006691","leukotriene metabolic process",1,1]
["GO:0006692","prostanoid metabolic process",1,1]
["GO:0006693","prostaglandin metabolic process",1,1]
["GO:0006695","cholesterol biosynthetic process",1,1]
["GO:0006700","C21-steroid hormone biosynthetic process",1,1]
["GO:0006704","glucocorticoid biosynthetic process",1,1]
["GO:0006706","steroid catabolic process",1,1]
["GO:0006720","isoprenoid metabolic process",1,1]
["GO:0006721","terpenoid metabolic process",1,1]
["GO:0006733","oxidoreduction coenzyme metabolic process",1,1]
["GO:0006739","NADP metabolic process",1,1]
["GO:0006754","ATP biosynthetic process",1,1]
["GO:0006760","folic acid-containing compound metabolic process",1,1]
["GO:0006766","vitamin metabolic process",1,1]
["GO:0006767","water-soluble vitamin metabolic process",1,1]
["GO:0006775","fat-soluble vitamin metabolic process",1,1]
["GO:0006776","vitamin A metabolic process",1,1]
["GO:0006778","porphyrin-containing compound metabolic process",1,1]
["GO:0006779","porphyrin-containing compound biosynthetic process",1,1]
["GO:0006783","heme biosynthetic process",1,1]
["GO:0006814","sodium ion transport",1,1]
["GO:0006818","hydrogen transport",1,1]
["GO:0006821","chloride transport",1,1]
["GO:0006825","copper ion transport",1,1]
["GO:0006829","zinc ion transport",1,1]
["GO:0006833","water transport",1,1]
["GO:0006882","cellular zinc ion homeostasis",1,1]
["GO:0006885","regulation of pH",1,1]
["GO:0006888","ER to Golgi vesicle-mediated transport",1,1]
["GO:0006891","intra-Golgi vesicle-mediated transport",1,1]
["GO:0006892","post-Golgi vesicle-mediated transport",1,1]
["GO:0006893","Golgi to plasma membrane transport",1,1]
["GO:0006900","membrane budding",1,1]
["GO:0006901","vesicle coating",1,1]
["GO:0006903","vesicle targeting",1,1]
["GO:0006904","vesicle docking involved in exocytosis",1,1]
["GO:0006906","vesicle fusion",1,1]
["GO:0006919","activation of cysteine-type endopeptidase activity involved in apoptotic process",1,1]
["GO:0006921","cellular component disassembly involved in apoptosis",1,1]
["GO:0006929","substrate-dependent cell migration",1,1]
["GO:0006937","regulation of muscle contraction",1,1]
["GO:0006939","smooth muscle contraction",1,1]
["GO:0006940","regulation of smooth muscle contraction",1,1]
["GO:0006942","regulation of striated muscle contraction",1,1]
["GO:0006953","acute-phase response",1,1]
["GO:0006956","complement activation",1,1]
["GO:0006958","complement activation, classical pathway",1,1]
["GO:0006959","humoral immune response",1,1]
["GO:0006968","cellular defense response",1,1]
["GO:0006970","response to osmotic stress",1,1]
["GO:0006972","hyperosmotic response",1,1]
["GO:0006984","ER-nucleus signaling pathway",1,1]
["GO:0006986","response to unfolded protein",1,1]
["GO:0006987","activation of signaling protein activity involved in unfolded protein response",1,1]
["GO:0007004","telomere maintenance via telomerase",1,1]
["GO:0007006","mitochondrial membrane organization",1,1]
["GO:0007019","microtubule depolymerization",1,1]
["GO:0007026","negative regulation of microtubule depolymerization",1,1]
["GO:0007029","endoplasmic reticulum organization",1,1]
["GO:0007031","peroxisome organization",1,1]
["GO:0007032","endosome organization",1,1]
["GO:0007034","vacuolar transport",1,1]
["GO:0007041","lysosomal transport",1,1]
["GO:0007088","regulation of mitosis",1,1]
["GO:0007090","regulation of S phase of mitotic cell cycle",1,1]
["GO:0007091","mitotic metaphase/anaphase transition",1,1]
["GO:0007094","mitotic cell cycle spindle assembly checkpoint",1,1]
["GO:0007127","meiosis I",1,1]
["GO:0007128","meiotic prophase I",1,1]
["GO:0007129","synapsis",1,1]
["GO:0007131","reciprocal meiotic recombination",1,1]
["GO:0007140","male meiosis",1,1]
["GO:0007159","leukocyte cell-cell adhesion",1,1]
["GO:0007164","establishment of tissue polarity",1,1]
["GO:0007176","regulation of epidermal growth factor-activated receptor activity",1,1]
["GO:0007204","elevation of cytosolic calcium ion concentration",1,1]
["GO:0007214","gamma-aminobutyric acid signaling pathway",1,1]
["GO:0007220","Notch receptor processing",1,1]
["GO:0007224","smoothened signaling pathway",1,1]
["GO:0007229","integrin-mediated signaling pathway",1,1]
["GO:0007260","tyrosine phosphorylation of STAT protein",1,1]
["GO:0007263","nitric oxide mediated signal transduction",1,1]
["GO:0007271","synaptic transmission, cholinergic",1,1]
["GO:0007292","female gamete generation",1,1]
["GO:0007339","binding of sperm to zona pellucida",1,1]
["GO:0007350","blastoderm segmentation",1,1]
["GO:0007351","tripartite regional subdivision",1,1]
["GO:0007379","segment specification",1,1]
["GO:0007398","ectoderm development",1,1]
["GO:0007405","neuroblast proliferation",1,1]
["GO:0007413","axonal fasciculation",1,1]
["GO:0007431","salivary gland development",1,1]
["GO:0007435","salivary gland morphogenesis",1,1]
["GO:0007492","endoderm development",1,1]
["GO:0007494","midgut development",1,1]
["GO:0007498","mesoderm development",1,1]
["GO:0007528","neuromuscular junction development",1,1]
["GO:0007530","sex determination",1,1]
["GO:0007566","embryo implantation",1,1]
["GO:0007569","cell aging",1,1]
["GO:0007585","respiratory gaseous exchange",1,1]
["GO:0007588","excretion",1,1]
["GO:0007589","body fluid secretion",1,1]
["GO:0007595","lactation",1,1]
["GO:0007597","blood coagulation, intrinsic pathway",1,1]
["GO:0007602","phototransduction",1,1]
["GO:0007605","sensory perception of sound",1,1]
["GO:0007606","sensory perception of chemical stimulus",1,1]
["GO:0007608","sensory perception of smell",1,1]
["GO:0007616","long-term memory",1,1]
["GO:0007618","mating",1,1]
["GO:0007620","copulation",1,1]
["GO:0007622","rhythmic behavior",1,1]
["GO:0007628","adult walking behavior",1,1]
["GO:0007631","feeding behavior",1,1]
["GO:0008016","regulation of heart contraction",1,1]
["GO:0008037","cell recognition",1,1]
["GO:0008038","neuron recognition",1,1]
["GO:0008045","motor axon guidance",1,1]
["GO:0008064","regulation of actin polymerization or depolymerization",1,1]
["GO:0008088","axon cargo transport",1,1]
["GO:0008154","actin polymerization or depolymerization",1,1]
["GO:0008156","negative regulation of DNA replication",1,1]
["GO:0008207","C21-steroid hormone metabolic process",1,1]
["GO:0008209","androgen metabolic process",1,1]
["GO:0008210","estrogen metabolic process",1,1]
["GO:0008211","glucocorticoid metabolic process",1,1]
["GO:0008214","protein dealkylation",1,1]
["GO:0008299","isoprenoid biosynthetic process",1,1]
["GO:0008333","endosome to lysosome transport",1,1]
["GO:0008334","histone mRNA metabolic process",1,1]
["GO:0008584","male gonad development",1,1]
["GO:0008589","regulation of smoothened signaling pathway",1,1]
["GO:0008593","regulation of Notch signaling pathway",1,1]
["GO:0008595","anterior/posterior axis specification, embryo",1,1]
["GO:0008608","attachment of spindle microtubules to kinetochore",1,1]
["GO:0008625","induction of apoptosis via death domain receptors",1,1]
["GO:0008643","carbohydrate transport",1,1]
["GO:0008645","hexose transport",1,1]
["GO:0009060","aerobic respiration",1,1]
["GO:0009062","fatty acid catabolic process",1,1]
["GO:0009064","glutamine family amino acid metabolic process",1,1]
["GO:0009065","glutamine family amino acid catabolic process",1,1]
["GO:0009066","aspartate family amino acid metabolic process",1,1]
["GO:0009067","aspartate family amino acid biosynthetic process",1,1]
["GO:0009068","aspartate family amino acid catabolic process",1,1]
["GO:0009072","aromatic amino acid family metabolic process",1,1]
["GO:0009074","aromatic amino acid family catabolic process",1,1]
["GO:0009084","glutamine family amino acid biosynthetic process",1,1]
["GO:0009109","coenzyme catabolic process",1,1]
["GO:0009110","vitamin biosynthetic process",1,1]
["GO:0009112","nucleobase metabolic process",1,1]
["GO:0009116","nucleoside metabolic process",1,1]
["GO:0009119","ribonucleoside metabolic process",1,1]
["GO:0009125","nucleoside monophosphate catabolic process",1,1]
["GO:0009126","purine nucleoside monophosphate metabolic process",1,1]
["GO:0009127","purine nucleoside monophosphate biosynthetic process",1,1]
["GO:0009132","nucleoside diphosphate metabolic process",1,1]
["GO:0009142","nucleoside triphosphate biosynthetic process",1,1]
["GO:0009145","purine nucleoside triphosphate biosynthetic process",1,1]
["GO:0009147","pyrimidine nucleoside triphosphate metabolic process",1,1]
["GO:0009152","purine ribonucleotide biosynthetic process",1,1]
["GO:0009156","ribonucleoside monophosphate biosynthetic process",1,1]
["GO:0009161","ribonucleoside monophosphate metabolic process",1,1]
["GO:0009163","nucleoside biosynthetic process",1,1]
["GO:0009164","nucleoside catabolic process",1,1]
["GO:0009167","purine ribonucleoside monophosphate metabolic process",1,1]
["GO:0009168","purine ribonucleoside monophosphate biosynthetic process",1,1]
["GO:0009201","ribonucleoside triphosphate biosynthetic process",1,1]
["GO:0009206","purine ribonucleoside triphosphate biosynthetic process",1,1]
["GO:0009218","pyrimidine ribonucleotide metabolic process",1,1]
["GO:0009220","pyrimidine ribonucleotide biosynthetic process",1,1]
["GO:0009225","nucleotide-sugar metabolic process",1,1]
["GO:0009250","glucan biosynthetic process",1,1]
["GO:0009251","glucan catabolic process",1,1]
["GO:0009260","ribonucleotide biosynthetic process",1,1]
["GO:0009262","deoxyribonucleotide metabolic process",1,1]
["GO:0009266","response to temperature stimulus",1,1]
["GO:0009268","response to pH",1,1]
["GO:0009303","rRNA transcription",1,1]
["GO:0009311","oligosaccharide metabolic process",1,1]
["GO:0009312","oligosaccharide biosynthetic process",1,1]
["GO:0009394","2'-deoxyribonucleotide metabolic process",1,1]
["GO:0009395","phospholipid catabolic process",1,1]
["GO:0009408","response to heat",1,1]
["GO:0009409","response to cold",1,1]
["GO:0009452","RNA capping",1,1]
["GO:0009581","detection of external stimulus",1,1]
["GO:0009582","detection of abiotic stimulus",1,1]
["GO:0009583","detection of light stimulus",1,1]
["GO:0009584","detection of visible light",1,1]
["GO:0009595","detection of biotic stimulus",1,1]
["GO:0009620","response to fungus",1,1]
["GO:0009651","response to salt stress",1,1]
["GO:0009880","embryonic pattern specification",1,1]
["GO:0009913","epidermal cell differentiation",1,1]
["GO:0009950","dorsal/ventral axis specification",1,1]
["GO:0009954","proximal/distal pattern formation",1,1]
["GO:0009988","cell-cell recognition",1,1]
["GO:0009994","oocyte differentiation",1,1]
["GO:0010002","cardioblast differentiation",1,1]
["GO:0010039","response to iron ion",1,1]
["GO:0010092","specification of organ identity",1,1]
["GO:0010226","response to lithium ion",1,1]
["GO:0010259","multicellular organismal aging",1,1]
["GO:0010389","regulation of G2/M transition of mitotic cell cycle",1,1]
["GO:0010390","histone monoubiquitination",1,1]
["GO:0010453","regulation of cell fate commitment",1,1]
["GO:0010458","exit from mitosis",1,1]
["GO:0010463","mesenchymal cell proliferation",1,1]
["GO:0010464","regulation of mesenchymal cell proliferation",1,1]
["GO:0010466","negative regulation of peptidase activity",1,1]
["GO:0010522","regulation of calcium ion transport into cytosol",1,1]
["GO:0010524","positive regulation of calcium ion transport into cytosol",1,1]
["GO:0010543","regulation of platelet activation",1,1]
["GO:0010559","regulation of glycoprotein biosynthetic process",1,1]
["GO:0010573","vascular endothelial growth factor production",1,1]
["GO:0010574","regulation of vascular endothelial growth factor production",1,1]
["GO:0010575","positive regulation vascular endothelial growth factor production",1,1]
["GO:0010594","regulation of endothelial cell migration",1,1]
["GO:0010595","positive regulation of endothelial cell migration",1,1]
["GO:0010596","negative regulation of endothelial cell migration",1,1]
["GO:0010611","regulation of cardiac muscle hypertrophy",1,1]
["GO:0010623","developmental programmed cell death",1,1]
["GO:0010631","epithelial cell migration",1,1]
["GO:0010632","regulation of epithelial cell migration",1,1]
["GO:0010657","muscle cell apoptosis",1,1]
["GO:0010660","regulation of muscle cell apoptosis",1,1]
["GO:0010675","regulation of cellular carbohydrate metabolic process",1,1]
["GO:0010676","positive regulation of cellular carbohydrate metabolic process",1,1]
["GO:0010677","negative regulation of cellular carbohydrate metabolic process",1,1]
["GO:0010712","regulation of collagen metabolic process",1,1]
["GO:0010714","positive regulation of collagen metabolic process",1,1]
["GO:0010717","regulation of epithelial to mesenchymal transition",1,1]
["GO:0010718","positive regulation of epithelial to mesenchymal transition",1,1]
["GO:0010770","positive regulation of cell morphogenesis involved in differentiation",1,1]
["GO:0010771","negative regulation of cell morphogenesis involved in differentiation",1,1]
["GO:0010799","regulation of peptidyl-threonine phosphorylation",1,1]
["GO:0010811","positive regulation of cell-substrate adhesion",1,1]
["GO:0010812","negative regulation of cell-substrate adhesion",1,1]
["GO:0010822","positive regulation of mitochondrion organization",1,1]
["GO:0010827","regulation of glucose transport",1,1]
["GO:0010828","positive regulation of glucose transport",1,1]
["GO:0010833","telomere maintenance via telomere lengthening",1,1]
["GO:0010862","positive regulation of pathway-restricted SMAD protein phosphorylation",1,1]
["GO:0010869","regulation of receptor biosynthetic process",1,1]
["GO:0010884","positive regulation of lipid storage",1,1]
["GO:0010894","negative regulation of steroid biosynthetic process",1,1]
["GO:0010906","regulation of glucose metabolic process",1,1]
["GO:0010907","positive regulation of glucose metabolic process",1,1]
["GO:0010921","regulation of phosphatase activity",1,1]
["GO:0010923","negative regulation of phosphatase activity",1,1]
["GO:0010948","negative regulation of cell cycle process",1,1]
["GO:0010950","positive regulation of endopeptidase activity",1,1]
["GO:0010951","negative regulation of endopeptidase activity",1,1]
["GO:0010952","positive regulation of peptidase activity",1,1]
["GO:0010962","regulation of glucan biosynthetic process",1,1]
["GO:0010970","microtubule-based transport",1,1]
["GO:0010976","positive regulation of neuron projection development",1,1]
["GO:0010977","negative regulation of neuron projection development",1,1]
["GO:0014003","oligodendrocyte development",1,1]
["GO:0014015","positive regulation of gliogenesis",1,1]
["GO:0014046","dopamine secretion",1,1]
["GO:0014059","regulation of dopamine secretion",1,1]
["GO:0014072","response to isoquinoline alkaloid",1,1]
["GO:0014073","response to tropane",1,1]
["GO:0014074","response to purine-containing compound",1,1]
["GO:0014743","regulation of muscle hypertrophy",1,1]
["GO:0014812","muscle cell migration",1,1]
["GO:0014855","striated muscle cell proliferation",1,1]
["GO:0014896","muscle hypertrophy",1,1]
["GO:0014897","striated muscle hypertrophy",1,1]
["GO:0014909","smooth muscle cell migration",1,1]
["GO:0014910","regulation of smooth muscle cell migration",1,1]
["GO:0015074","DNA integration",1,1]
["GO:0015669","gas transport",1,1]
["GO:0015698","inorganic anion transport",1,1]
["GO:0015711","organic anion transport",1,1]
["GO:0015721","bile acid and bile salt transport",1,1]
["GO:0015749","monosaccharide transport",1,1]
["GO:0015758","glucose transport",1,1]
["GO:0015800","acidic amino acid transport",1,1]
["GO:0015804","neutral amino acid transport",1,1]
["GO:0015807","L-amino acid transport",1,1]
["GO:0015813","L-glutamate transport",1,1]
["GO:0015931","nucleobase-containing compound transport",1,1]
["GO:0015949","nucleobase-containing small molecule interconversion",1,1]
["GO:0015985","energy coupled proton transport, down electrochemical gradient",1,1]
["GO:0015986","ATP synthesis coupled proton transport",1,1]
["GO:0015988","energy coupled proton transport, against electrochemical gradient",1,1]
["GO:0015991","ATP hydrolysis coupled proton transport",1,1]
["GO:0015992","proton transport",1,1]
["GO:0016051","carbohydrate biosynthetic process",1,1]
["GO:0016052","carbohydrate catabolic process",1,1]
["GO:0016064","immunoglobulin mediated immune response",1,1]
["GO:0016072","rRNA metabolic process",1,1]
["GO:0016101","diterpenoid metabolic process",1,1]
["GO:0016126","sterol biosynthetic process",1,1]
["GO:0016236","macroautophagy",1,1]
["GO:0016254","preassembly of GPI anchor in ER membrane",1,1]
["GO:0016266","O-glycan processing",1,1]
["GO:0016338","calcium-independent cell-cell adhesion",1,1]
["GO:0016441","posttranscriptional gene silencing",1,1]
["GO:0016444","somatic cell DNA recombination",1,1]
["GO:0016445","somatic diversification of immunoglobulins",1,1]
["GO:0016447","somatic recombination of immunoglobulin gene segments",1,1]
["GO:0016485","protein processing",1,1]
["GO:0016486","peptide hormone processing",1,1]
["GO:0016525","negative regulation of angiogenesis",1,1]
["GO:0016574","histone ubiquitination",1,1]
["GO:0016577","histone demethylation",1,1]
["GO:0016578","histone deubiquitination",1,1]
["GO:0016579","protein deubiquitination",1,1]
["GO:0016601","Rac protein signal transduction",1,1]
["GO:0016925","protein sumoylation",1,1]
["GO:0016998","cell wall macromolecule catabolic process",1,1]
["GO:0017085","response to insecticide",1,1]
["GO:0017144","drug metabolic process",1,1]
["GO:0017145","stem cell division",1,1]
["GO:0017148","negative regulation of translation",1,1]
["GO:0018149","peptide cross-linking",1,1]
["GO:0018196","peptidyl-asparagine modification",1,1]
["GO:0018200","peptidyl-glutamic acid modification",1,1]
["GO:0018208","peptidyl-proline modification",1,1]
["GO:0018279","protein N-linked glycosylation via asparagine",1,1]
["GO:0018410","C-terminal protein amino acid modification",1,1]
["GO:0019048","virus-host interaction",1,1]
["GO:0019059","initiation of viral infection",1,1]
["GO:0019079","viral genome replication",1,1]
["GO:0019098","reproductive behavior",1,1]
["GO:0019218","regulation of steroid metabolic process",1,1]
["GO:0019229","regulation of vasoconstriction",1,1]
["GO:0019318","hexose metabolic process",1,1]
["GO:0019319","hexose biosynthetic process",1,1]
["GO:0019320","hexose catabolic process",1,1]
["GO:0019362","pyridine nucleotide metabolic process",1,1]
["GO:0019363","pyridine nucleotide biosynthetic process",1,1]
["GO:0019370","leukotriene biosynthetic process",1,1]
["GO:0019400","alditol metabolic process",1,1]
["GO:0019433","triglyceride catabolic process",1,1]
["GO:0019438","aromatic compound biosynthetic process",1,1]
["GO:0019439","aromatic compound catabolic process",1,1]
["GO:0019585","glucuronate metabolic process",1,1]
["GO:0019674","NAD metabolic process",1,1]
["GO:0019722","calcium-mediated signaling",1,1]
["GO:0019724","B cell mediated immunity",1,1]
["GO:0019748","secondary metabolic process",1,1]
["GO:0019751","polyol metabolic process",1,1]
["GO:0019835","cytolysis",1,1]
["GO:0021510","spinal cord development",1,1]
["GO:0021515","cell differentiation in spinal cord",1,1]
["GO:0021516","dorsal spinal cord development",1,1]
["GO:0021517","ventral spinal cord development",1,1]
["GO:0021522","spinal cord motor neuron differentiation",1,1]
["GO:0021532","neural tube patterning",1,1]
["GO:0021533","cell differentiation in hindbrain",1,1]
["GO:0021545","cranial nerve development",1,1]
["GO:0021602","cranial nerve morphogenesis",1,1]
["GO:0021675","nerve development",1,1]
["GO:0021680","cerebellar Purkinje cell layer development",1,1]
["GO:0021695","cerebellar cortex development",1,1]
["GO:0021696","cerebellar cortex morphogenesis",1,1]
["GO:0021697","cerebellar cortex formation",1,1]
["GO:0021795","cerebral cortex cell migration",1,1]
["GO:0021871","forebrain regionalization",1,1]
["GO:0021872","forebrain generation of neurons",1,1]
["GO:0021879","forebrain neuron differentiation",1,1]
["GO:0021885","forebrain cell migration",1,1]
["GO:0021895","cerebral cortex neuron differentiation",1,1]
["GO:0021953","central nervous system neuron differentiation",1,1]
["GO:0021954","central nervous system neuron development",1,1]
["GO:0021955","central nervous system neuron axonogenesis",1,1]
["GO:0022029","telencephalon cell migration",1,1]
["GO:0022401","negative adaptation of signaling pathway",1,1]
["GO:0022404","molting cycle process",1,1]
["GO:0022405","hair cycle process",1,1]
["GO:0022406","membrane docking",1,1]
["GO:0022409","positive regulation of cell-cell adhesion",1,1]
["GO:0022410","circadian sleep/wake cycle process",1,1]
["GO:0022412","cellular process involved in reproduction in multicellular organism",1,1]
["GO:0022600","digestive system process",1,1]
["GO:0022613","ribonucleoprotein complex biogenesis",1,1]
["GO:0022616","DNA strand elongation",1,1]
["GO:0022618","ribonucleoprotein complex assembly",1,1]
["GO:0023058","adaptation of signaling pathway",1,1]
["GO:0030004","cellular monovalent inorganic cation homeostasis",1,1]
["GO:0030041","actin filament polymerization",1,1]
["GO:0030042","actin filament depolymerization",1,1]
["GO:0030048","actin filament-based movement",1,1]
["GO:0030049","muscle filament sliding",1,1]
["GO:0030071","regulation of mitotic metaphase/anaphase transition",1,1]
["GO:0030101","natural killer cell activation",1,1]
["GO:0030104","water homeostasis",1,1]
["GO:0030149","sphingolipid catabolic process",1,1]
["GO:0030166","proteoglycan biosynthetic process",1,1]
["GO:0030178","negative regulation of Wnt receptor signaling pathway",1,1]
["GO:0030183","B cell differentiation",1,1]
["GO:0030193","regulation of blood coagulation",1,1]
["GO:0030194","positive regulation of blood coagulation",1,1]
["GO:0030195","negative regulation of blood coagulation",1,1]
["GO:0030199","collagen fibril organization",1,1]
["GO:0030201","heparan sulfate proteoglycan metabolic process",1,1]
["GO:0030203","glycosaminoglycan metabolic process",1,1]
["GO:0030204","chondroitin sulfate metabolic process",1,1]
["GO:0030212","hyaluronan metabolic process",1,1]
["GO:0030216","keratinocyte differentiation",1,1]
["GO:0030219","megakaryocyte differentiation",1,1]
["GO:0030224","monocyte differentiation",1,1]
["GO:0030225","macrophage differentiation",1,1]
["GO:0030239","myofibril assembly",1,1]
["GO:0030260","entry into host cell",1,1]
["GO:0030262","apoptotic nuclear change",1,1]
["GO:0030279","negative regulation of ossification",1,1]
["GO:0030282","bone mineralization",1,1]
["GO:0030316","osteoclast differentiation",1,1]
["GO:0030317","sperm motility",1,1]
["GO:0030318","melanocyte differentiation",1,1]
["GO:0030323","respiratory tube development",1,1]
["GO:0030324","lung development",1,1]
["GO:0030325","adrenal gland development",1,1]
["GO:0030431","sleep",1,1]
["GO:0030433","ER-associated protein catabolic process",1,1]
["GO:0030500","regulation of bone mineralization",1,1]
["GO:0030501","positive regulation of bone mineralization",1,1]
["GO:0030511","positive regulation of transforming growth factor beta receptor signaling pathway",1,1]
["GO:0030513","positive regulation of BMP signaling pathway",1,1]
["GO:0030517","negative regulation of axon extension",1,1]
["GO:0030539","male genitalia development",1,1]
["GO:0030574","collagen catabolic process",1,1]
["GO:0030593","neutrophil chemotaxis",1,1]
["GO:0030595","leukocyte chemotaxis",1,1]
["GO:0030641","regulation of cellular pH",1,1]
["GO:0030705","cytoskeleton-dependent intracellular transport",1,1]
["GO:0030728","ovulation",1,1]
["GO:0030832","regulation of actin filament length",1,1]
["GO:0030833","regulation of actin filament polymerization",1,1]
["GO:0030834","regulation of actin filament depolymerization",1,1]
["GO:0030835","negative regulation of actin filament depolymerization",1,1]
["GO:0030837","negative regulation of actin filament polymerization",1,1]
["GO:0030838","positive regulation of actin filament polymerization",1,1]
["GO:0030851","granulocyte differentiation",1,1]
["GO:0030856","regulation of epithelial cell differentiation",1,1]
["GO:0030857","negative regulation of epithelial cell differentiation",1,1]
["GO:0030858","positive regulation of epithelial cell differentiation",1,1]
["GO:0030865","cortical cytoskeleton organization",1,1]
["GO:0030866","cortical actin cytoskeleton organization",1,1]
["GO:0030878","thyroid gland development",1,1]
["GO:0030879","mammary gland development",1,1]
["GO:0030901","midbrain development",1,1]
["GO:0030947","regulation of vascular endothelial growth factor receptor signaling pathway",1,1]
["GO:0030949","positive regulation of vascular endothelial growth factor receptor signaling pathway",1,1]
["GO:0030968","endoplasmic reticulum unfolded protein response",1,1]
["GO:0031032","actomyosin structure organization",1,1]
["GO:0031047","gene silencing by RNA",1,1]
["GO:0031055","chromatin remodeling at centromere",1,1]
["GO:0031069","hair follicle morphogenesis",1,1]
["GO:0031076","embryonic camera-type eye development",1,1]
["GO:0031099","regeneration",1,1]
["GO:0031100","organ regeneration",1,1]
["GO:0031102","neuron projection regeneration",1,1]
["GO:0031103","axon regeneration",1,1]
["GO:0031109","microtubule polymerization or depolymerization",1,1]
["GO:0031110","regulation of microtubule polymerization or depolymerization",1,1]
["GO:0031111","negative regulation of microtubule polymerization or depolymerization",1,1]
["GO:0031112","positive regulation of microtubule polymerization or depolymerization",1,1]
["GO:0031113","regulation of microtubule polymerization",1,1]
["GO:0031114","regulation of microtubule depolymerization",1,1]
["GO:0031123","RNA 3'-end processing",1,1]
["GO:0031124","mRNA 3'-end processing",1,1]
["GO:0031128","developmental induction",1,1]
["GO:0031214","biomineral tissue development",1,1]
["GO:0031290","retinal ganglion cell axon guidance",1,1]
["GO:0031294","lymphocyte costimulation",1,1]
["GO:0031295","T cell costimulation",1,1]
["GO:0031330","negative regulation of cellular catabolic process",1,1]
["GO:0031333","negative regulation of protein complex assembly",1,1]
["GO:0031343","positive regulation of cell killing",1,1]
["GO:0031424","keratinization",1,1]
["GO:0031497","chromatin assembly",1,1]
["GO:0031577","spindle checkpoint",1,1]
["GO:0031638","zymogen activation",1,1]
["GO:0031640","killing of cells of other organism",1,1]
["GO:0031645","negative regulation of neurological system process",1,1]
["GO:0031648","protein destabilization",1,1]
["GO:0031649","heat generation",1,1]
["GO:0031929","TOR signaling cascade",1,1]
["GO:0031952","regulation of protein autophosphorylation",1,1]
["GO:0031960","response to corticosteroid stimulus",1,1]
["GO:0032006","regulation of TOR signaling cascade",1,1]
["GO:0032011","ARF protein signal transduction",1,1]
["GO:0032069","regulation of nuclease activity",1,1]
["GO:0032075","positive regulation of nuclease activity",1,1]
["GO:0032088","negative regulation of NF-kappaB transcription factor activity",1,1]
["GO:0032094","response to food",1,1]
["GO:0032095","regulation of response to food",1,1]
["GO:0032104","regulation of response to extracellular stimulus",1,1]
["GO:0032107","regulation of response to nutrient levels",1,1]
["GO:0032200","telomere organization",1,1]
["GO:0032201","telomere maintenance via semi-conservative replication",1,1]
["GO:0032228","regulation of synaptic transmission, GABAergic",1,1]
["GO:0032271","regulation of protein polymerization",1,1]
["GO:0032272","negative regulation of protein polymerization",1,1]
["GO:0032273","positive regulation of protein polymerization",1,1]
["GO:0032309","icosanoid secretion",1,1]
["GO:0032319","regulation of Rho GTPase activity",1,1]
["GO:0032321","positive regulation of Rho GTPase activity",1,1]
["GO:0032330","regulation of chondrocyte differentiation",1,1]
["GO:0032350","regulation of hormone metabolic process",1,1]
["GO:0032369","negative regulation of lipid transport",1,1]
["GO:0032392","DNA geometric change",1,1]
["GO:0032410","negative regulation of transporter activity",1,1]
["GO:0032411","positive regulation of transporter activity",1,1]
["GO:0032413","negative regulation of ion transmembrane transporter activity",1,1]
["GO:0032414","positive regulation of ion transmembrane transporter activity",1,1]
["GO:0032465","regulation of cytokinesis",1,1]
["GO:0032467","positive regulation of cytokinesis",1,1]
["GO:0032480","negative regulation of type I interferon production",1,1]
["GO:0032489","regulation of Cdc42 protein signal transduction",1,1]
["GO:0032508","DNA duplex unwinding",1,1]
["GO:0032570","response to progesterone stimulus",1,1]
["GO:0032613","interleukin-10 production",1,1]
["GO:0032620","interleukin-17 production",1,1]
["GO:0032623","interleukin-2 production",1,1]
["GO:0032633","interleukin-4 production",1,1]
["GO:0032637","interleukin-8 production",1,1]
["GO:0032651","regulation of interleukin-1 beta production",1,1]
["GO:0032652","regulation of interleukin-1 production",1,1]
["GO:0032653","regulation of interleukin-10 production",1,1]
["GO:0032660","regulation of interleukin-17 production",1,1]
["GO:0032663","regulation of interleukin-2 production",1,1]
["GO:0032673","regulation of interleukin-4 production",1,1]
["GO:0032677","regulation of interleukin-8 production",1,1]
["GO:0032728","positive regulation of interferon-beta production",1,1]
["GO:0032729","positive regulation of interferon-gamma production",1,1]
["GO:0032731","positive regulation of interleukin-1 beta production",1,1]
["GO:0032732","positive regulation of interleukin-1 production",1,1]
["GO:0032733","positive regulation of interleukin-10 production",1,1]
["GO:0032757","positive regulation of interleukin-8 production",1,1]
["GO:0032768","regulation of monooxygenase activity",1,1]
["GO:0032770","positive regulation of monooxygenase activity",1,1]
["GO:0032800","receptor biosynthetic process",1,1]
["GO:0032814","regulation of natural killer cell activation",1,1]
["GO:0032835","glomerulus development",1,1]
["GO:0032845","negative regulation of homeostatic process",1,1]
["GO:0032846","positive regulation of homeostatic process",1,1]
["GO:0032855","positive regulation of Rac GTPase activity",1,1]
["GO:0032862","activation of Rho GTPase activity",1,1]
["GO:0032873","negative regulation of stress-activated MAPK cascade",1,1]
["GO:0032881","regulation of polysaccharide metabolic process",1,1]
["GO:0032885","regulation of polysaccharide biosynthetic process",1,1]
["GO:0032886","regulation of microtubule-based process",1,1]
["GO:0032890","regulation of organic acid transport",1,1]
["GO:0032945","negative regulation of mononuclear cell proliferation",1,1]
["GO:0032963","collagen metabolic process",1,1]
["GO:0032964","collagen biosynthetic process",1,1]
["GO:0032965","regulation of collagen biosynthetic process",1,1]
["GO:0032967","positive regulation of collagen biosynthetic process",1,1]
["GO:0033002","muscle cell proliferation",1,1]
["GO:0033003","regulation of mast cell activation",1,1]
["GO:0033006","regulation of mast cell activation involved in immune response",1,1]
["GO:0033013","tetrapyrrole metabolic process",1,1]
["GO:0033014","tetrapyrrole biosynthetic process",1,1]
["GO:0033059","cellular pigmentation",1,1]
["GO:0033077","T cell differentiation in thymus",1,1]
["GO:0033081","regulation of T cell differentiation in thymus",1,1]
["GO:0033108","mitochondrial respiratory chain complex assembly",1,1]
["GO:0033119","negative regulation of RNA splicing",1,1]
["GO:0033135","regulation of peptidyl-serine phosphorylation",1,1]
["GO:0033138","positive regulation of peptidyl-serine phosphorylation",1,1]
["GO:0033158","regulation of protein import into nucleus, translocation",1,1]
["GO:0033198","response to ATP",1,1]
["GO:0033205","cell cycle cytokinesis",1,1]
["GO:0033209","tumor necrosis factor-mediated signaling pathway",1,1]
["GO:0033261","regulation of S phase",1,1]
["GO:0033275","actin-myosin filament sliding",1,1]
["GO:0033280","response to vitamin D",1,1]
["GO:0033555","multicellular organismal response to stress",1,1]
["GO:0033574","response to testosterone stimulus",1,1]
["GO:0033598","mammary gland epithelial cell proliferation",1,1]
["GO:0033619","membrane protein proteolysis",1,1]
["GO:0033627","cell adhesion mediated by integrin",1,1]
["GO:0033628","regulation of cell adhesion mediated by integrin",1,1]
["GO:0033630","positive regulation of cell adhesion mediated by integrin",1,1]
["GO:0033687","osteoblast proliferation",1,1]
["GO:0033688","regulation of osteoblast proliferation",1,1]
["GO:0033692","cellular polysaccharide biosynthetic process",1,1]
["GO:0033762","response to glucagon stimulus",1,1]
["GO:0033865","nucleoside bisphosphate metabolic process",1,1]
["GO:0033993","response to lipid",1,1]
["GO:0034067","protein localization in Golgi apparatus",1,1]
["GO:0034080","CenH3-containing nucleosome assembly at centromere",1,1]
["GO:0034103","regulation of tissue remodeling",1,1]
["GO:0034105","positive regulation of tissue remodeling",1,1]
["GO:0034121","regulation of toll-like receptor signaling pathway",1,1]
["GO:0034199","activation of protein kinase A activity",1,1]
["GO:0034332","adherens junction organization",1,1]
["GO:0034340","response to type I interferon",1,1]
["GO:0034367","macromolecular complex remodeling",1,1]
["GO:0034368","protein-lipid complex remodeling",1,1]
["GO:0034369","plasma lipoprotein particle remodeling",1,1]
["GO:0034381","plasma lipoprotein particle clearance",1,1]
["GO:0034446","substrate adhesion-dependent cell spreading",1,1]
["GO:0034453","microtubule anchoring",1,1]
["GO:0034502","protein localization to chromosome",1,1]
["GO:0034605","cellular response to heat",1,1]
["GO:0034612","response to tumor necrosis factor",1,1]
["GO:0034620","cellular response to unfolded protein",1,1]
["GO:0034637","cellular carbohydrate biosynthetic process",1,1]
["GO:0034644","cellular response to UV",1,1]
["GO:0034694","response to prostaglandin stimulus",1,1]
["GO:0034698","response to gonadotropin stimulus",1,1]
["GO:0034724","DNA replication-independent nucleosome organization",1,1]
["GO:0034754","cellular hormone metabolic process",1,1]
["GO:0034976","response to endoplasmic reticulum stress",1,1]
["GO:0035020","regulation of Rac protein signal transduction",1,1]
["GO:0035023","regulation of Rho protein signal transduction",1,1]
["GO:0035036","sperm-egg recognition",1,1]
["GO:0035050","embryonic heart tube development",1,1]
["GO:0035051","cardiac cell differentiation",1,1]
["GO:0035088","establishment or maintenance of apical/basal cell polarity",1,1]
["GO:0035115","embryonic forelimb morphogenesis",1,1]
["GO:0035116","embryonic hindlimb morphogenesis",1,1]
["GO:0035136","forelimb morphogenesis",1,1]
["GO:0035137","hindlimb morphogenesis",1,1]
["GO:0035162","embryonic hemopoiesis",1,1]
["GO:0035194","posttranscriptional gene silencing by RNA",1,1]
["GO:0035195","gene silencing by miRNA",1,1]
["GO:0035264","multicellular organism growth",1,1]
["GO:0035265","organ growth",1,1]
["GO:0035272","exocrine system development",1,1]
["GO:0035303","regulation of dephosphorylation",1,1]
["GO:0035329","hippo signaling cascade",1,1]
["GO:0035335","peptidyl-tyrosine dephosphorylation",1,1]
["GO:0035336","long-chain fatty-acyl-CoA metabolic process",1,1]
["GO:0035338","long-chain fatty-acyl-CoA biosynthetic process",1,1]
["GO:0035411","catenin import into nucleus",1,1]
["GO:0035412","regulation of catenin import into nucleus",1,1]
["GO:0035567","non-canonical Wnt receptor signaling pathway",1,1]
["GO:0035710","CD4-positive, alpha-beta T cell activation",1,1]
["GO:0035725","sodium ion transmembrane transport",1,1]
["GO:0035809","regulation of urine volume",1,1]
["GO:0035812","renal sodium excretion",1,1]
["GO:0035813","regulation of renal sodium excretion",1,1]
["GO:0035821","modification of morphology or physiology of other organism",1,1]
["GO:0035825","reciprocal DNA recombination",1,1]
["GO:0035850","epithelial cell differentiation involved in kidney development",1,1]
["GO:0035924","cellular response to vascular endothelial growth factor stimulus",1,1]
["GO:0035966","response to topologically incorrect protein",1,1]
["GO:0035967","cellular response to topologically incorrect protein",1,1]
["GO:0040001","establishment of mitotic spindle localization",1,1]
["GO:0040014","regulation of multicellular organism growth",1,1]
["GO:0040018","positive regulation of multicellular organism growth",1,1]
["GO:0040036","regulation of fibroblast growth factor receptor signaling pathway",1,1]
["GO:0042036","negative regulation of cytokine biosynthetic process",1,1]
["GO:0042044","fluid transport",1,1]
["GO:0042058","regulation of epidermal growth factor receptor signaling pathway",1,1]
["GO:0042059","negative regulation of epidermal growth factor receptor signaling pathway",1,1]
["GO:0042092","type 2 immune response",1,1]
["GO:0042093","T-helper cell differentiation",1,1]
["GO:0042094","interleukin-2 biosynthetic process",1,1]
["GO:0042095","interferon-gamma biosynthetic process",1,1]
["GO:0042102","positive regulation of T cell proliferation",1,1]
["GO:0042104","positive regulation of activated T cell proliferation",1,1]
["GO:0042119","neutrophil activation",1,1]
["GO:0042129","regulation of T cell proliferation",1,1]
["GO:0042130","negative regulation of T cell proliferation",1,1]
["GO:0042133","neurotransmitter metabolic process",1,1]
["GO:0042147","retrograde transport, endosome to Golgi",1,1]
["GO:0042168","heme metabolic process",1,1]
["GO:0042220","response to cocaine",1,1]
["GO:0042226","interleukin-6 biosynthetic process",1,1]
["GO:0042246","tissue regeneration",1,1]
["GO:0042254","ribosome biogenesis",1,1]
["GO:0042255","ribosome assembly",1,1]
["GO:0042267","natural killer cell mediated cytotoxicity",1,1]
["GO:0042269","regulation of natural killer cell mediated cytotoxicity",1,1]
["GO:0042274","ribosomal small subunit biogenesis",1,1]
["GO:0042278","purine nucleoside metabolic process",1,1]
["GO:0042303","molting cycle",1,1]
["GO:0042310","vasoconstriction",1,1]
["GO:0042312","regulation of vasodilation",1,1]
["GO:0042345","regulation of NF-kappaB import into nucleus",1,1]
["GO:0042346","positive regulation of NF-kappaB import into nucleus",1,1]
["GO:0042348","NF-kappaB import into nucleus",1,1]
["GO:0042359","vitamin D metabolic process",1,1]
["GO:0042362","fat-soluble vitamin biosynthetic process",1,1]
["GO:0042375","quinone cofactor metabolic process",1,1]
["GO:0042398","cellular modified amino acid biosynthetic process",1,1]
["GO:0042401","cellular biogenic amine biosynthetic process",1,1]
["GO:0042402","cellular biogenic amine catabolic process",1,1]
["GO:0042403","thyroid hormone metabolic process",1,1]
["GO:0042430","indole-containing compound metabolic process",1,1]
["GO:0042440","pigment metabolic process",1,1]
["GO:0042445","hormone metabolic process",1,1]
["GO:0042446","hormone biosynthetic process",1,1]
["GO:0042451","purine nucleoside biosynthetic process",1,1]
["GO:0042455","ribonucleoside biosynthetic process",1,1]
["GO:0042461","photoreceptor cell development",1,1]
["GO:0042462","eye photoreceptor cell development",1,1]
["GO:0042474","middle ear morphogenesis",1,1]
["GO:0042475","odontogenesis of dentin-containing tooth",1,1]
["GO:0042476","odontogenesis",1,1]
["GO:0042481","regulation of odontogenesis",1,1]
["GO:0042503","tyrosine phosphorylation of Stat3 protein",1,1]
["GO:0042506","tyrosine phosphorylation of Stat5 protein",1,1]
["GO:0042509","regulation of tyrosine phosphorylation of STAT protein",1,1]
["GO:0042516","regulation of tyrosine phosphorylation of Stat3 protein",1,1]
["GO:0042517","positive regulation of tyrosine phosphorylation of Stat3 protein",1,1]
["GO:0042522","regulation of tyrosine phosphorylation of Stat5 protein",1,1]
["GO:0042523","positive regulation of tyrosine phosphorylation of Stat5 protein",1,1]
["GO:0042531","positive regulation of tyrosine phosphorylation of STAT protein",1,1]
["GO:0042533","tumor necrosis factor biosynthetic process",1,1]
["GO:0042534","regulation of tumor necrosis factor biosynthetic process",1,1]
["GO:0042551","neuron maturation",1,1]
["GO:0042558","pteridine-containing compound metabolic process",1,1]
["GO:0042559","pteridine-containing compound biosynthetic process",1,1]
["GO:0042573","retinoic acid metabolic process",1,1]
["GO:0042596","fear response",1,1]
["GO:0042633","hair cycle",1,1]
["GO:0042659","regulation of cell fate specification",1,1]
["GO:0042730","fibrinolysis",1,1]
["GO:0042733","embryonic digit morphogenesis",1,1]
["GO:0042742","defense response to bacterium",1,1]
["GO:0042744","hydrogen peroxide catabolic process",1,1]
["GO:0042745","circadian sleep/wake cycle",1,1]
["GO:0042749","regulation of circadian sleep/wake cycle",1,1]
["GO:0042755","eating behavior",1,1]
["GO:0042771","DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis",1,1]
["GO:0042772","DNA damage response, signal transduction resulting in transcription",1,1]
["GO:0042773","ATP synthesis coupled electron transport",1,1]
["GO:0042775","mitochondrial ATP synthesis coupled electron transport",1,1]
["GO:0042982","amyloid precursor protein metabolic process",1,1]
["GO:0042994","cytoplasmic sequestering of transcription factor",1,1]
["GO:0043038","amino acid activation",1,1]
["GO:0043039","tRNA aminoacylation",1,1]
["GO:0043043","peptide biosynthetic process",1,1]
["GO:0043088","regulation of Cdc42 GTPase activity",1,1]
["GO:0043094","cellular metabolic compound salvage",1,1]
["GO:0043101","purine-containing compound salvage",1,1]
["GO:0043114","regulation of vascular permeability",1,1]
["GO:0043149","stress fiber assembly",1,1]
["GO:0043154","negative regulation of cysteine-type endopeptidase activity involved in apoptotic process",1,1]
["GO:0043200","response to amino acid stimulus",1,1]
["GO:0043242","negative regulation of protein complex disassembly",1,1]
["GO:0043244","regulation of protein complex disassembly",1,1]
["GO:0043255","regulation of carbohydrate biosynthetic process",1,1]
["GO:0043266","regulation of potassium ion transport",1,1]
["GO:0043270","positive regulation of ion transport",1,1]
["GO:0043271","negative regulation of ion transport",1,1]
["GO:0043277","apoptotic cell clearance",1,1]
["GO:0043278","response to morphine",1,1]
["GO:0043280","positive regulation of cysteine-type endopeptidase activity involved in apoptotic process",1,1]
["GO:0043281","regulation of cysteine-type endopeptidase activity involved in apoptotic process",1,1]
["GO:0043299","leukocyte degranulation",1,1]
["GO:0043300","regulation of leukocyte degranulation",1,1]
["GO:0043303","mast cell degranulation",1,1]
["GO:0043304","regulation of mast cell degranulation",1,1]
["GO:0043367","CD4-positive, alpha-beta T cell differentiation",1,1]
["GO:0043370","regulation of CD4-positive, alpha-beta T cell differentiation",1,1]
["GO:0043372","positive regulation of CD4-positive, alpha-beta T cell differentiation",1,1]
["GO:0043392","negative regulation of DNA binding",1,1]
["GO:0043407","negative regulation of MAP kinase activity",1,1]
["GO:0043409","negative regulation of MAPK cascade",1,1]
["GO:0043449","cellular alkene metabolic process",1,1]
["GO:0043450","alkene biosynthetic process",1,1]
["GO:0043467","regulation of generation of precursor metabolites and energy",1,1]
["GO:0043470","regulation of carbohydrate catabolic process",1,1]
["GO:0043471","regulation of cellular carbohydrate catabolic process",1,1]
["GO:0043484","regulation of RNA splicing",1,1]
["GO:0043486","histone exchange",1,1]
["GO:0043491","protein kinase B signaling cascade",1,1]
["GO:0043516","regulation of DNA damage response, signal transduction by p53 class mediator",1,1]
["GO:0043525","positive regulation of neuron apoptosis",1,1]
["GO:0043526","neuroprotection",1,1]
["GO:0043534","blood vessel endothelial cell migration",1,1]
["GO:0043535","regulation of blood vessel endothelial cell migration",1,1]
["GO:0043536","positive regulation of blood vessel endothelial cell migration",1,1]
["GO:0043542","endothelial cell migration",1,1]
["GO:0043550","regulation of lipid kinase activity",1,1]
["GO:0043551","regulation of phosphatidylinositol 3-kinase activity",1,1]
["GO:0043552","positive regulation of phosphatidylinositol 3-kinase activity",1,1]
["GO:0043567","regulation of insulin-like growth factor receptor signaling pathway",1,1]
["GO:0043574","peroxisomal transport",1,1]
["GO:0043576","regulation of respiratory gaseous exchange",1,1]
["GO:0043586","tongue development",1,1]
["GO:0043588","skin development",1,1]
["GO:0043603","cellular amide metabolic process",1,1]
["GO:0043616","keratinocyte proliferation",1,1]
["GO:0043620","regulation of DNA-dependent transcription in response to stress",1,1]
["GO:0043623","cellular protein complex assembly",1,1]
["GO:0043631","RNA polyadenylation",1,1]
["GO:0043648","dicarboxylic acid metabolic process",1,1]
["GO:0043666","regulation of phosphoprotein phosphatase activity",1,1]
["GO:0043687","post-translational protein modification",1,1]
["GO:0043900","regulation of multi-organism process",1,1]
["GO:0043901","negative regulation of multi-organism process",1,1]
["GO:0043903","regulation of symbiosis, encompassing mutualism through parasitism",1,1]
["GO:0043921","modulation by host of viral transcription",1,1]
["GO:0043928","exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay",1,1]
["GO:0043967","histone H4 acetylation",1,1]
["GO:0043981","histone H4-K5 acetylation",1,1]
["GO:0043982","histone H4-K8 acetylation",1,1]
["GO:0044003","modification by symbiont of host morphology or physiology",1,1]
["GO:0044036","cell wall macromolecule metabolic process",1,1]
["GO:0044042","glucan metabolic process",1,1]
["GO:0044058","regulation of digestive system process",1,1]
["GO:0044060","regulation of endocrine process",1,1]
["GO:0044062","regulation of excretion",1,1]
["GO:0044089","positive regulation of cellular component biogenesis",1,1]
["GO:0044110","growth involved in symbiotic interaction",1,1]
["GO:0044116","growth of symbiont involved in interaction with host",1,1]
["GO:0044117","growth of symbiont in host",1,1]
["GO:0044126","regulation of growth of symbiont in host",1,1]
["GO:0044130","negative regulation of growth of symbiont in host",1,1]
["GO:0044144","modulation of growth of symbiont involved in interaction with host",1,1]
["GO:0044146","negative regulation of growth of symbiont involved in interaction with host",1,1]
["GO:0044236","multicellular organismal metabolic process",1,1]
["GO:0044241","lipid digestion",1,1]
["GO:0044242","cellular lipid catabolic process",1,1]
["GO:0044243","multicellular organismal catabolic process",1,1]
["GO:0044246","regulation of multicellular organismal metabolic process",1,1]
["GO:0044247","cellular polysaccharide catabolic process",1,1]
["GO:0044253","positive regulation of multicellular organismal metabolic process",1,1]
["GO:0044259","multicellular organismal macromolecule metabolic process",1,1]
["GO:0044264","cellular polysaccharide metabolic process",1,1]
["GO:0044269","glycerol ether catabolic process",1,1]
["GO:0044275","cellular carbohydrate catabolic process",1,1]
["GO:0044349","DNA excision",1,1]
["GO:0044403","symbiosis, encompassing mutualism through parasitism",1,1]
["GO:0044409","entry into host",1,1]
["GO:0045058","T cell selection",1,1]
["GO:0045061","thymic T cell selection",1,1]
["GO:0045069","regulation of viral genome replication",1,1]
["GO:0045071","negative regulation of viral genome replication",1,1]
["GO:0045072","regulation of interferon-gamma biosynthetic process",1,1]
["GO:0045076","regulation of interleukin-2 biosynthetic process",1,1]
["GO:0045103","intermediate filament-based process",1,1]
["GO:0045104","intermediate filament cytoskeleton organization",1,1]
["GO:0045124","regulation of bone resorption",1,1]
["GO:0045132","meiotic chromosome segregation",1,1]
["GO:0045168","cell-cell signaling involved in cell fate commitment",1,1]
["GO:0045187","regulation of circadian sleep/wake cycle, sleep",1,1]
["GO:0045190","isotype switching",1,1]
["GO:0045191","regulation of isotype switching",1,1]
["GO:0045214","sarcomere organization",1,1]
["GO:0045446","endothelial cell differentiation",1,1]
["GO:0045453","bone resorption",1,1]
["GO:0045454","cell redox homeostasis",1,1]
["GO:0045576","mast cell activation",1,1]
["GO:0045577","regulation of B cell differentiation",1,1]
["GO:0045580","regulation of T cell differentiation",1,1]
["GO:0045581","negative regulation of T cell differentiation",1,1]
["GO:0045582","positive regulation of T cell differentiation",1,1]
["GO:0045600","positive regulation of fat cell differentiation",1,1]
["GO:0045604","regulation of epidermal cell differentiation",1,1]
["GO:0045616","regulation of keratinocyte differentiation",1,1]
["GO:0045619","regulation of lymphocyte differentiation",1,1]
["GO:0045620","negative regulation of lymphocyte differentiation",1,1]
["GO:0045621","positive regulation of lymphocyte differentiation",1,1]
["GO:0045622","regulation of T-helper cell differentiation",1,1]
["GO:0045665","negative regulation of neuron differentiation",1,1]
["GO:0045669","positive regulation of osteoblast differentiation",1,1]
["GO:0045670","regulation of osteoclast differentiation",1,1]
["GO:0045671","negative regulation of osteoclast differentiation",1,1]
["GO:0045682","regulation of epidermis development",1,1]
["GO:0045684","positive regulation of epidermis development",1,1]
["GO:0045685","regulation of glial cell differentiation",1,1]
["GO:0045686","negative regulation of glial cell differentiation",1,1]
["GO:0045687","positive regulation of glial cell differentiation",1,1]
["GO:0045730","respiratory burst",1,1]
["GO:0045737","positive regulation of cyclin-dependent protein kinase activity",1,1]
["GO:0045739","positive regulation of DNA repair",1,1]
["GO:0045740","positive regulation of DNA replication",1,1]
["GO:0045742","positive regulation of epidermal growth factor receptor signaling pathway",1,1]
["GO:0045767","regulation of anti-apoptosis",1,1]
["GO:0045768","positive regulation of anti-apoptosis",1,1]
["GO:0045777","positive regulation of blood pressure",1,1]
["GO:0045778","positive regulation of ossification",1,1]
["GO:0045785","positive regulation of cell adhesion",1,1]
["GO:0045787","positive regulation of cell cycle",1,1]
["GO:0045806","negative regulation of endocytosis",1,1]
["GO:0045807","positive regulation of endocytosis",1,1]
["GO:0045814","negative regulation of gene expression, epigenetic",1,1]
["GO:0045823","positive regulation of heart contraction",1,1]
["GO:0045833","negative regulation of lipid metabolic process",1,1]
["GO:0045839","negative regulation of mitosis",1,1]
["GO:0045840","positive regulation of mitosis",1,1]
["GO:0045841","negative regulation of mitotic metaphase/anaphase transition",1,1]
["GO:0045843","negative regulation of striated muscle tissue development",1,1]
["GO:0045851","pH reduction",1,1]
["GO:0045861","negative regulation of proteolysis",1,1]
["GO:0045879","negative regulation of smoothened signaling pathway",1,1]
["GO:0045880","positive regulation of smoothened signaling pathway",1,1]
["GO:0045884","regulation of survival gene product expression",1,1]
["GO:0045907","positive regulation of vasoconstriction",1,1]
["GO:0045909","positive regulation of vasodilation",1,1]
["GO:0045912","negative regulation of carbohydrate metabolic process",1,1]
["GO:0045913","positive regulation of carbohydrate metabolic process",1,1]
["GO:0045922","negative regulation of fatty acid metabolic process",1,1]
["GO:0045923","positive regulation of fatty acid metabolic process",1,1]
["GO:0045930","negative regulation of mitotic cell cycle",1,1]
["GO:0045931","positive regulation of mitotic cell cycle",1,1]
["GO:0045932","negative regulation of muscle contraction",1,1]
["GO:0045933","positive regulation of muscle contraction",1,1]
["GO:0045939","negative regulation of steroid metabolic process",1,1]
["GO:0045940","positive regulation of steroid metabolic process",1,1]
["GO:0045947","negative regulation of translational initiation",1,1]
["GO:0045954","positive regulation of natural killer cell mediated cytotoxicity",1,1]
["GO:0045987","positive regulation of smooth muscle contraction",1,1]
["GO:0046006","regulation of activated T cell proliferation",1,1]
["GO:0046128","purine ribonucleoside metabolic process",1,1]
["GO:0046129","purine ribonucleoside biosynthetic process",1,1]
["GO:0046131","pyrimidine ribonucleoside metabolic process",1,1]
["GO:0046134","pyrimidine nucleoside biosynthetic process",1,1]
["GO:0046135","pyrimidine nucleoside catabolic process",1,1]
["GO:0046148","pigment biosynthetic process",1,1]
["GO:0046164","alcohol catabolic process",1,1]
["GO:0046165","alcohol biosynthetic process",1,1]
["GO:0046323","glucose import",1,1]
["GO:0046324","regulation of glucose import",1,1]
["GO:0046326","positive regulation of glucose import",1,1]
["GO:0046329","negative regulation of JNK cascade",1,1]
["GO:0046356","acetyl-CoA catabolic process",1,1]
["GO:0046364","monosaccharide biosynthetic process",1,1]
["GO:0046365","monosaccharide catabolic process",1,1]
["GO:0046425","regulation of JAK-STAT cascade",1,1]
["GO:0046427","positive regulation of JAK-STAT cascade",1,1]
["GO:0046456","icosanoid biosynthetic process",1,1]
["GO:0046457","prostanoid biosynthetic process",1,1]
["GO:0046461","neutral lipid catabolic process",1,1]
["GO:0046464","acylglycerol catabolic process",1,1]
["GO:0046466","membrane lipid catabolic process",1,1]
["GO:0046496","nicotinamide nucleotide metabolic process",1,1]
["GO:0046503","glycerolipid catabolic process",1,1]
["GO:0046513","ceramide biosynthetic process",1,1]
["GO:0046519","sphingoid metabolic process",1,1]
["GO:0046520","sphingoid biosynthetic process",1,1]
["GO:0046530","photoreceptor cell differentiation",1,1]
["GO:0046546","development of primary male sexual characteristics",1,1]
["GO:0046579","positive regulation of Ras protein signal transduction",1,1]
["GO:0046605","regulation of centrosome cycle",1,1]
["GO:0046620","regulation of organ growth",1,1]
["GO:0046626","regulation of insulin receptor signaling pathway",1,1]
["GO:0046627","negative regulation of insulin receptor signaling pathway",1,1]
["GO:0046631","alpha-beta T cell activation",1,1]
["GO:0046632","alpha-beta T cell differentiation",1,1]
["GO:0046633","alpha-beta T cell proliferation",1,1]
["GO:0046634","regulation of alpha-beta T cell activation",1,1]
["GO:0046635","positive regulation of alpha-beta T cell activation",1,1]
["GO:0046636","negative regulation of alpha-beta T cell activation",1,1]
["GO:0046637","regulation of alpha-beta T cell differentiation",1,1]
["GO:0046638","positive regulation of alpha-beta T cell differentiation",1,1]
["GO:0046661","male sex differentiation",1,1]
["GO:0046676","negative regulation of insulin secretion",1,1]
["GO:0046685","response to arsenic-containing substance",1,1]
["GO:0046688","response to copper ion",1,1]
["GO:0046697","decidualization",1,1]
["GO:0046717","acid secretion",1,1]
["GO:0046718","entry of virus into host cell",1,1]
["GO:0046782","regulation of viral transcription",1,1]
["GO:0046785","microtubule polymerization",1,1]
["GO:0046825","regulation of protein export from nucleus",1,1]
["GO:0046849","bone remodeling",1,1]
["GO:0046850","regulation of bone remodeling",1,1]
["GO:0046885","regulation of hormone biosynthetic process",1,1]
["GO:0046888","negative regulation of hormone secretion",1,1]
["GO:0048008","platelet-derived growth factor receptor signaling pathway",1,1]
["GO:0048010","vascular endothelial growth factor receptor signaling pathway",1,1]
["GO:0048013","ephrin receptor signaling pathway",1,1]
["GO:0048024","regulation of nuclear mRNA splicing, via spliceosome",1,1]
["GO:0048048","embryonic eye morphogenesis",1,1]
["GO:0048103","somatic stem cell division",1,1]
["GO:0048199","vesicle targeting, to, from or within Golgi",1,1]
["GO:0048246","macrophage chemotaxis",1,1]
["GO:0048247","lymphocyte chemotaxis",1,1]
["GO:0048259","regulation of receptor-mediated endocytosis",1,1]
["GO:0048260","positive regulation of receptor-mediated endocytosis",1,1]
["GO:0048265","response to pain",1,1]
["GO:0048278","vesicle docking",1,1]
["GO:0048284","organelle fusion",1,1]
["GO:0048286","lung alveolus development",1,1]
["GO:0048332","mesoderm morphogenesis",1,1]
["GO:0048333","mesodermal cell differentiation",1,1]
["GO:0048384","retinoic acid receptor signaling pathway",1,1]
["GO:0048477","oogenesis",1,1]
["GO:0048483","autonomic nervous system development",1,1]
["GO:0048484","enteric nervous system development",1,1]
["GO:0048485","sympathetic nervous system development",1,1]
["GO:0048488","synaptic vesicle endocytosis",1,1]
["GO:0048512","circadian behavior",1,1]
["GO:0048520","positive regulation of behavior",1,1]
["GO:0048521","negative regulation of behavior",1,1]
["GO:0048524","positive regulation of viral reproduction",1,1]
["GO:0048525","negative regulation of viral reproduction",1,1]
["GO:0048536","spleen development",1,1]
["GO:0048546","digestive tract morphogenesis",1,1]
["GO:0048557","embryonic digestive tract morphogenesis",1,1]
["GO:0048565","digestive tract development",1,1]
["GO:0048566","embryonic digestive tract development",1,1]
["GO:0048596","embryonic camera-type eye morphogenesis",1,1]
["GO:0048599","oocyte development",1,1]
["GO:0048635","negative regulation of muscle organ development",1,1]
["GO:0048640","negative regulation of developmental growth",1,1]
["GO:0048644","muscle organ morphogenesis",1,1]
["GO:0048645","organ formation",1,1]
["GO:0048659","smooth muscle cell proliferation",1,1]
["GO:0048660","regulation of smooth muscle cell proliferation",1,1]
["GO:0048661","positive regulation of smooth muscle cell proliferation",1,1]
["GO:0048662","negative regulation of smooth muscle cell proliferation",1,1]
["GO:0048701","embryonic cranial skeleton morphogenesis",1,1]
["GO:0048704","embryonic skeletal system morphogenesis",1,1]
["GO:0048706","embryonic skeletal system development",1,1]
["GO:0048708","astrocyte differentiation",1,1]
["GO:0048709","oligodendrocyte differentiation",1,1]
["GO:0048710","regulation of astrocyte differentiation",1,1]
["GO:0048713","regulation of oligodendrocyte differentiation",1,1]
["GO:0048730","epidermis morphogenesis",1,1]
["GO:0048738","cardiac muscle tissue development",1,1]
["GO:0048745","smooth muscle tissue development",1,1]
["GO:0048754","branching morphogenesis of a tube",1,1]
["GO:0048806","genitalia development",1,1]
["GO:0048813","dendrite morphogenesis",1,1]
["GO:0048814","regulation of dendrite morphogenesis",1,1]
["GO:0048821","erythrocyte development",1,1]
["GO:0048844","artery morphogenesis",1,1]
["GO:0048846","axon extension involved in axon guidance",1,1]
["GO:0048854","brain morphogenesis",1,1]
["GO:0048871","multicellular organismal homeostasis",1,1]
["GO:0048873","homeostasis of number of cells within a tissue",1,1]
["GO:0050000","chromosome localization",1,1]
["GO:0050432","catecholamine secretion",1,1]
["GO:0050433","regulation of catecholamine secretion",1,1]
["GO:0050434","positive regulation of viral transcription",1,1]
["GO:0050482","arachidonic acid secretion",1,1]
["GO:0050654","chondroitin sulfate proteoglycan metabolic process",1,1]
["GO:0050657","nucleic acid transport",1,1]
["GO:0050658","RNA transport",1,1]
["GO:0050672","negative regulation of lymphocyte proliferation",1,1]
["GO:0050684","regulation of mRNA processing",1,1]
["GO:0050688","regulation of defense response to virus",1,1]
["GO:0050690","regulation of defense response to virus by virus",1,1]
["GO:0050691","regulation of defense response to virus by host",1,1]
["GO:0050704","regulation of interleukin-1 secretion",1,1]
["GO:0050706","regulation of interleukin-1 beta secretion",1,1]
["GO:0050709","negative regulation of protein secretion",1,1]
["GO:0050710","negative regulation of cytokine secretion",1,1]
["GO:0050716","positive regulation of interleukin-1 secretion",1,1]
["GO:0050718","positive regulation of interleukin-1 beta secretion",1,1]
["GO:0050732","negative regulation of peptidyl-tyrosine phosphorylation",1,1]
["GO:0050764","regulation of phagocytosis",1,1]
["GO:0050766","positive regulation of phagocytosis",1,1]
["GO:0050773","regulation of dendrite development",1,1]
["GO:0050792","regulation of viral reproduction",1,1]
["GO:0050798","activated T cell proliferation",1,1]
["GO:0050802","circadian sleep/wake cycle, sleep",1,1]
["GO:0050805","negative regulation of synaptic transmission",1,1]
["GO:0050810","regulation of steroid biosynthetic process",1,1]
["GO:0050818","regulation of coagulation",1,1]
["GO:0050819","negative regulation of coagulation",1,1]
["GO:0050820","positive regulation of coagulation",1,1]
["GO:0050829","defense response to Gram-negative bacterium",1,1]
["GO:0050830","defense response to Gram-positive bacterium",1,1]
["GO:0050832","defense response to fungus",1,1]
["GO:0050848","regulation of calcium-mediated signaling",1,1]
["GO:0050850","positive regulation of calcium-mediated signaling",1,1]
["GO:0050853","B cell receptor signaling pathway",1,1]
["GO:0050854","regulation of antigen receptor-mediated signaling pathway",1,1]
["GO:0050856","regulation of T cell receptor signaling pathway",1,1]
["GO:0050863","regulation of T cell activation",1,1]
["GO:0050866","negative regulation of cell activation",1,1]
["GO:0050868","negative regulation of T cell activation",1,1]
["GO:0050869","negative regulation of B cell activation",1,1]
["GO:0050870","positive regulation of T cell activation",1,1]
["GO:0050873","brown fat cell differentiation",1,1]
["GO:0050879","multicellular organismal movement",1,1]
["GO:0050881","musculoskeletal movement",1,1]
["GO:0050886","endocrine process",1,1]
["GO:0050891","multicellular organismal water homeostasis",1,1]
["GO:0050892","intestinal absorption",1,1]
["GO:0050906","detection of stimulus involved in sensory perception",1,1]
["GO:0050907","detection of chemical stimulus involved in sensory perception",1,1]
["GO:0050909","sensory perception of taste",1,1]
["GO:0050911","detection of chemical stimulus involved in sensory perception of smell",1,1]
["GO:0050912","detection of chemical stimulus involved in sensory perception of taste",1,1]
["GO:0050918","positive chemotaxis",1,1]
["GO:0050920","regulation of chemotaxis",1,1]
["GO:0050921","positive regulation of chemotaxis",1,1]
["GO:0050922","negative regulation of chemotaxis",1,1]
["GO:0050926","regulation of positive chemotaxis",1,1]
["GO:0050927","positive regulation of positive chemotaxis",1,1]
["GO:0050954","sensory perception of mechanical stimulus",1,1]
["GO:0050994","regulation of lipid catabolic process",1,1]
["GO:0050995","negative regulation of lipid catabolic process",1,1]
["GO:0050996","positive regulation of lipid catabolic process",1,1]
["GO:0050999","regulation of nitric-oxide synthase activity",1,1]
["GO:0051004","regulation of lipoprotein lipase activity",1,1]
["GO:0051028","mRNA transport",1,1]
["GO:0051043","regulation of membrane protein ectodomain proteolysis",1,1]
["GO:0051048","negative regulation of secretion",1,1]
["GO:0051053","negative regulation of DNA metabolic process",1,1]
["GO:0051054","positive regulation of DNA metabolic process",1,1]
["GO:0051055","negative regulation of lipid biosynthetic process",1,1]
["GO:0051057","positive regulation of small GTPase mediated signal transduction",1,1]
["GO:0051084","'de novo' posttranslational protein folding",1,1]
["GO:0051148","negative regulation of muscle cell differentiation",1,1]
["GO:0051168","nuclear export",1,1]
["GO:0051180","vitamin transport",1,1]
["GO:0051181","cofactor transport",1,1]
["GO:0051187","cofactor catabolic process",1,1]
["GO:0051208","sequestering of calcium ion",1,1]
["GO:0051209","release of sequestered calcium ion into cytosol",1,1]
["GO:0051236","establishment of RNA localization",1,1]
["GO:0051238","sequestering of metal ion",1,1]
["GO:0051250","negative regulation of lymphocyte activation",1,1]
["GO:0051258","protein polymerization",1,1]
["GO:0051261","protein depolymerization",1,1]
["GO:0051279","regulation of release of sequestered calcium ion into cytosol",1,1]
["GO:0051282","regulation of sequestering of calcium ion",1,1]
["GO:0051283","negative regulation of sequestering of calcium ion",1,1]
["GO:0051291","protein heterooligomerization",1,1]
["GO:0051293","establishment of spindle localization",1,1]
["GO:0051302","regulation of cell division",1,1]
["GO:0051303","establishment of chromosome localization",1,1]
["GO:0051310","metaphase plate congression",1,1]
["GO:0051313","attachment of spindle microtubules to chromosome",1,1]
["GO:0051324","prophase",1,1]
["GO:0051346","negative regulation of hydrolase activity",1,1]
["GO:0051354","negative regulation of oxidoreductase activity",1,1]
["GO:0051384","response to glucocorticoid stimulus",1,1]
["GO:0051385","response to mineralocorticoid stimulus",1,1]
["GO:0051412","response to corticosterone stimulus",1,1]
["GO:0051452","intracellular pH reduction",1,1]
["GO:0051453","regulation of intracellular pH",1,1]
["GO:0051480","cytosolic calcium ion homeostasis",1,1]
["GO:0051492","regulation of stress fiber assembly",1,1]
["GO:0051496","positive regulation of stress fiber assembly",1,1]
["GO:0051568","histone H3-K4 methylation",1,1]
["GO:0051592","response to calcium ion",1,1]
["GO:0051604","protein maturation",1,1]
["GO:0051647","nucleus localization",1,1]
["GO:0051648","vesicle localization",1,1]
["GO:0051650","establishment of vesicle localization",1,1]
["GO:0051653","spindle localization",1,1]
["GO:0051656","establishment of organelle localization",1,1]
["GO:0051668","localization within membrane",1,1]
["GO:0051693","actin filament capping",1,1]
["GO:0051701","interaction with host",1,1]
["GO:0051702","interaction with symbiont",1,1]
["GO:0051781","positive regulation of cell division",1,1]
["GO:0051783","regulation of nuclear division",1,1]
["GO:0051784","negative regulation of nuclear division",1,1]
["GO:0051785","positive regulation of nuclear division",1,1]
["GO:0051806","entry into cell of other organism involved in symbiotic interaction",1,1]
["GO:0051817","modification of morphology or physiology of other organism involved in symbiotic interaction",1,1]
["GO:0051828","entry into other organism involved in symbiotic interaction",1,1]
["GO:0051851","modification by host of symbiont morphology or physiology",1,1]
["GO:0051875","pigment granule localization",1,1]
["GO:0051893","regulation of focal adhesion assembly",1,1]
["GO:0051896","regulation of protein kinase B signaling cascade",1,1]
["GO:0051897","positive regulation of protein kinase B signaling cascade",1,1]
["GO:0051898","negative regulation of protein kinase B signaling cascade",1,1]
["GO:0051923","sulfation",1,1]
["GO:0051926","negative regulation of calcium ion transport",1,1]
["GO:0051928","positive regulation of calcium ion transport",1,1]
["GO:0051930","regulation of sensory perception of pain",1,1]
["GO:0051931","regulation of sensory perception",1,1]
["GO:0051932","synaptic transmission, GABAergic",1,1]
["GO:0051952","regulation of amine transport",1,1]
["GO:0051953","negative regulation of amine transport",1,1]
["GO:0051954","positive regulation of amine transport",1,1]
["GO:0051963","regulation of synapse assembly",1,1]
["GO:0051970","negative regulation of transmission of nerve impulse",1,1]
["GO:0051983","regulation of chromosome segregation",1,1]
["GO:0052126","movement in host environment",1,1]
["GO:0052192","movement in environment of other organism involved in symbiotic interaction",1,1]
["GO:0052312","modulation of transcription in other organism involved in symbiotic interaction",1,1]
["GO:0052472","modulation by host of symbiont transcription",1,1]
["GO:0052547","regulation of peptidase activity",1,1]
["GO:0052548","regulation of endopeptidase activity",1,1]
["GO:0055006","cardiac cell development",1,1]
["GO:0055007","cardiac muscle cell differentiation",1,1]
["GO:0055008","cardiac muscle tissue morphogenesis",1,1]
["GO:0055010","ventricular cardiac muscle tissue morphogenesis",1,1]
["GO:0055012","ventricular cardiac muscle cell differentiation",1,1]
["GO:0055013","cardiac muscle cell development",1,1]
["GO:0055017","cardiac muscle tissue growth",1,1]
["GO:0055021","regulation of cardiac muscle tissue growth",1,1]
["GO:0055024","regulation of cardiac muscle tissue development",1,1]
["GO:0055067","monovalent inorganic cation homeostasis",1,1]
["GO:0055069","zinc ion homeostasis",1,1]
["GO:0055078","sodium ion homeostasis",1,1]
["GO:0055081","anion homeostasis",1,1]
["GO:0055117","regulation of cardiac muscle contraction",1,1]
["GO:0055123","digestive system development",1,1]
["GO:0060026","convergent extension",1,1]
["GO:0060038","cardiac muscle cell proliferation",1,1]
["GO:0060042","retina morphogenesis in camera-type eye",1,1]
["GO:0060043","regulation of cardiac muscle cell proliferation",1,1]
["GO:0060047","heart contraction",1,1]
["GO:0060048","cardiac muscle contraction",1,1]
["GO:0060071","Wnt receptor signaling pathway, planar cell polarity pathway",1,1]
["GO:0060119","inner ear receptor cell development",1,1]
["GO:0060216","definitive hemopoiesis",1,1]
["GO:0060231","mesenchymal to epithelial transition",1,1]
["GO:0060326","cell chemotaxis",1,1]
["GO:0060330","regulation of response to interferon-gamma",1,1]
["GO:0060334","regulation of interferon-gamma-mediated signaling pathway",1,1]
["GO:0060337","type I interferon-mediated signaling pathway",1,1]
["GO:0060338","regulation of type I interferon-mediated signaling pathway",1,1]
["GO:0060343","trabecula formation",1,1]
["GO:0060389","pathway-restricted SMAD protein phosphorylation",1,1]
["GO:0060393","regulation of pathway-restricted SMAD protein phosphorylation",1,1]
["GO:0060401","cytosolic calcium ion transport",1,1]
["GO:0060402","calcium ion transport into cytosol",1,1]
["GO:0060411","cardiac septum morphogenesis",1,1]
["GO:0060412","ventricular septum morphogenesis",1,1]
["GO:0060415","muscle tissue morphogenesis",1,1]
["GO:0060419","heart growth",1,1]
["GO:0060420","regulation of heart growth",1,1]
["GO:0060425","lung morphogenesis",1,1]
["GO:0060428","lung epithelium development",1,1]
["GO:0060441","epithelial tube branching involved in lung morphogenesis",1,1]
["GO:0060443","mammary gland morphogenesis",1,1]
["GO:0060444","branching involved in mammary gland duct morphogenesis",1,1]
["GO:0060445","branching involved in salivary gland morphogenesis",1,1]
["GO:0060479","lung cell differentiation",1,1]
["GO:0060487","lung epithelial cell differentiation",1,1]
["GO:0060571","morphogenesis of an epithelial fold",1,1]
["GO:0060572","morphogenesis of an epithelial bud",1,1]
["GO:0060600","dichotomous subdivision of an epithelial terminal unit",1,1]
["GO:0060602","branch elongation of an epithelium",1,1]
["GO:0060603","mammary gland duct morphogenesis",1,1]
["GO:0060612","adipose tissue development",1,1]
["GO:0060644","mammary gland epithelial cell differentiation",1,1]
["GO:0060674","placenta blood vessel development",1,1]
["GO:0060675","ureteric bud morphogenesis",1,1]
["GO:0060688","regulation of morphogenesis of a branching structure",1,1]
["GO:0060711","labyrinthine layer development",1,1]
["GO:0060713","labyrinthine layer morphogenesis",1,1]
["GO:0060749","mammary gland alveolus development",1,1]
["GO:0060760","positive regulation of response to cytokine stimulus",1,1]
["GO:0060788","ectodermal placode formation",1,1]
["GO:0060795","cell fate commitment involved in formation of primary germ layers",1,1]
["GO:0060840","artery development",1,1]
["GO:0060986","endocrine hormone secretion",1,1]
["GO:0060993","kidney morphogenesis",1,1]
["GO:0060996","dendritic spine development",1,1]
["GO:0060997","dendritic spine morphogenesis",1,1]
["GO:0060998","regulation of dendritic spine development",1,1]
["GO:0061005","cell differentiation involved in kidney development",1,1]
["GO:0061035","regulation of cartilage development",1,1]
["GO:0061041","regulation of wound healing",1,1]
["GO:0061077","chaperone-mediated protein folding",1,1]
["GO:0061097","regulation of protein tyrosine kinase activity",1,1]
["GO:0061098","positive regulation of protein tyrosine kinase activity",1,1]
["GO:0061099","negative regulation of protein tyrosine kinase activity",1,1]
["GO:0061138","morphogenesis of a branching epithelium",1,1]
["GO:0061180","mammary gland epithelium development",1,1]
["GO:0061245","establishment or maintenance of bipolar cell polarity",1,1]
["GO:0061311","cell surface receptor signaling pathway involved in heart development",1,1]
["GO:0061326","renal tubule development",1,1]
["GO:0061333","renal tubule morphogenesis",1,1]
["GO:0061371","determination of heart left/right asymmetry",1,1]
["GO:0061377","mammary gland lobule development",1,1]
["GO:0061383","trabecula morphogenesis",1,1]
["GO:0065004","protein-DNA complex assembly",1,1]
["GO:0070076","histone lysine demethylation",1,1]
["GO:0070167","regulation of biomineral tissue development",1,1]
["GO:0070168","negative regulation of biomineral tissue development",1,1]
["GO:0070169","positive regulation of biomineral tissue development",1,1]
["GO:0070192","chromosome organization involved in meiosis",1,1]
["GO:0070227","lymphocyte apoptosis",1,1]
["GO:0070228","regulation of lymphocyte apoptosis",1,1]
["GO:0070229","negative regulation of lymphocyte apoptosis",1,1]
["GO:0070231","T cell apoptosis",1,1]
["GO:0070232","regulation of T cell apoptosis",1,1]
["GO:0070252","actin-mediated cell contraction",1,1]
["GO:0070303","negative regulation of stress-activated protein kinase signaling cascade",1,1]
["GO:0070306","lens fiber cell differentiation",1,1]
["GO:0070328","triglyceride homeostasis",1,1]
["GO:0070371","ERK1 and ERK2 cascade",1,1]
["GO:0070372","regulation of ERK1 and ERK2 cascade",1,1]
["GO:0070373","negative regulation of ERK1 and ERK2 cascade",1,1]
["GO:0070374","positive regulation of ERK1 and ERK2 cascade",1,1]
["GO:0070507","regulation of microtubule cytoskeleton organization",1,1]
["GO:0070542","response to fatty acid",1,1]
["GO:0070585","protein localization in mitochondrion",1,1]
["GO:0070588","calcium ion transmembrane transport",1,1]
["GO:0070613","regulation of protein processing",1,1]
["GO:0070646","protein modification by small protein removal",1,1]
["GO:0070664","negative regulation of leukocyte proliferation",1,1]
["GO:0070723","response to cholesterol",1,1]
["GO:0070741","response to interleukin-6",1,1]
["GO:0070873","regulation of glycogen metabolic process",1,1]
["GO:0070875","positive regulation of glycogen metabolic process",1,1]
["GO:0070988","demethylation",1,1]
["GO:0071173","spindle assembly checkpoint",1,1]
["GO:0071174","mitotic cell cycle spindle checkpoint",1,1]
["GO:0071229","cellular response to acid",1,1]
["GO:0071230","cellular response to amino acid stimulus",1,1]
["GO:0071248","cellular response to metal ion",1,1]
["GO:0071277","cellular response to calcium ion",1,1]
["GO:0071285","cellular response to lithium ion",1,1]
["GO:0071312","cellular response to alkaloid",1,1]
["GO:0071320","cellular response to cAMP",1,1]
["GO:0071356","cellular response to tumor necrosis factor",1,1]
["GO:0071357","cellular response to type I interferon",1,1]
["GO:0071359","cellular response to dsRNA",1,1]
["GO:0071377","cellular response to glucagon stimulus",1,1]
["GO:0071384","cellular response to corticosteroid stimulus",1,1]
["GO:0071385","cellular response to glucocorticoid stimulus",1,1]
["GO:0071396","cellular response to lipid",1,1]
["GO:0071407","cellular response to organic cyclic compound",1,1]
["GO:0071417","cellular response to organic nitrogen",1,1]
["GO:0071418","cellular response to amine stimulus",1,1]
["GO:0071436","sodium ion export",1,1]
["GO:0071453","cellular response to oxygen levels",1,1]
["GO:0071456","cellular response to hypoxia",1,1]
["GO:0071478","cellular response to radiation",1,1]
["GO:0071479","cellular response to ionizing radiation",1,1]
["GO:0071482","cellular response to light stimulus",1,1]
["GO:0071514","genetic imprinting",1,1]
["GO:0071554","cell wall organization or biogenesis",1,1]
["GO:0071599","otic vesicle development",1,1]
["GO:0071604","transforming growth factor beta production",1,1]
["GO:0071634","regulation of transforming growth factor beta production",1,1]
["GO:0071695","anatomical structure maturation",1,1]
["GO:0071696","ectodermal placode development",1,1]
["GO:0071697","ectodermal placode morphogenesis",1,1]
["GO:0071715","icosanoid transport",1,1]
["GO:0071804","cellular potassium ion transport",1,1]
["GO:0071805","potassium ion transmembrane transport",1,1]
["GO:0071826","ribonucleoprotein complex subunit organization",1,1]
["GO:0071843","cellular component biogenesis at cellular level",1,1]
["GO:0071887","leukocyte apoptosis",1,1]
["GO:0071897","DNA biosynthetic process",1,1]
["GO:0072001","renal system development",1,1]
["GO:0072006","nephron development",1,1]
["GO:0072009","nephron epithelium development",1,1]
["GO:0072012","glomerulus vasculature development",1,1]
["GO:0072028","nephron morphogenesis",1,1]
["GO:0072073","kidney epithelium development",1,1]
["GO:0072077","renal vesicle morphogenesis",1,1]
["GO:0072078","nephron tubule morphogenesis",1,1]
["GO:0072080","nephron tubule development",1,1]
["GO:0072087","renal vesicle development",1,1]
["GO:0072088","nephron epithelium morphogenesis",1,1]
["GO:0072132","mesenchyme morphogenesis",1,1]
["GO:0072170","metanephric tubule development",1,1]
["GO:0072207","metanephric epithelium development",1,1]
["GO:0072210","metanephric nephron development",1,1]
["GO:0072215","regulation of metanephros development",1,1]
["GO:0072224","metanephric glomerulus development",1,1]
["GO:0072234","metanephric nephron tubule development",1,1]
["GO:0072243","metanephric nephron epithelium development",1,1]
["GO:0072273","metanephric nephron morphogenesis",1,1]
["GO:0072283","metanephric renal vesicle morphogenesis",1,1]
["GO:0072329","monocarboxylic acid catabolic process",1,1]
["GO:0072332","signal transduction by p53 class mediator resulting in induction of apoptosis",1,1]
["GO:0072376","protein activation cascade",1,1]
["GO:0072378","blood coagulation, fibrin clot formation",1,1]
["GO:0072384","organelle transport along microtubule",1,1]
["GO:0072524","pyridine-containing compound metabolic process",1,1]
["GO:0072525","pyridine-containing compound biosynthetic process",1,1]
["GO:0072527","pyrimidine-containing compound metabolic process",1,1]
["GO:0072528","pyrimidine-containing compound biosynthetic process",1,1]
["GO:0072529","pyrimidine-containing compound catabolic process",1,1]
["GO:0072595","maintenance of protein localization to organelle",1,1]
["GO:0072600","establishment of protein localization in Golgi",1,1]
["GO:0072655","establishment of protein localization in mitochondrion",1,1]
["GO:0072662","protein localization to peroxisome",1,1]
["GO:0072663","establishment of protein localization to peroxisome",1,1]
["GO:0072676","lymphocyte migration",1,1]
["GO:0072678","T cell migration",1,1]
["GO:0090022","regulation of neutrophil chemotaxis",1,1]
["GO:0090023","positive regulation of neutrophil chemotaxis",1,1]
["GO:0090090","negative regulation of canonical Wnt receptor signaling pathway",1,1]
["GO:0090100","positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway",1,1]
["GO:0090102","cochlea development",1,1]
["GO:0090103","cochlea morphogenesis",1,1]
["GO:0090109","regulation of cell-substrate junction assembly",1,1]
["GO:0090130","tissue migration",1,1]
["GO:0090132","epithelium migration",1,1]
["GO:0090175","regulation of establishment of planar polarity",1,1]
["GO:0090181","regulation of cholesterol metabolic process",1,1]
["GO:0090183","regulation of kidney development",1,1]
["GO:0090184","positive regulation of kidney development",1,1]
["GO:0090189","regulation of branching involved in ureteric bud morphogenesis",1,1]
["GO:0090190","positive regulation of branching involved in ureteric bud morphogenesis",1,1]
["GO:0090200","positive regulation of release of cytochrome c from mitochondria",1,1]
["GO:0090218","positive regulation of lipid kinase activity",1,1]
["GO:0090278","negative regulation of peptide hormone secretion",1,1]
["GO:0090287","regulation of cellular response to growth factor stimulus",1,1]
["GO:0090305","nucleic acid phosphodiester bond hydrolysis",1,1]
["GO:0090329","regulation of DNA-dependent DNA replication",1,1]
["GO:0090342","regulation of cell aging",1,1]
["GO:0090398","cellular senescence",1,1]
["GO:0097061","dendritic spine organization",1,1]
["GO:0097190","apoptotic signaling pathway",1,1]
["GO:0097191","extrinsic apoptotic signaling pathway",1,1]
["GO:0097193","intrinsic apoptotic signaling pathway",1,1]
["GO:0097202","activation of cysteine-type endopeptidase activity",1,1]
["GO:1900046","regulation of hemostasis",1,1]
["GO:1900047","negative regulation of hemostasis",1,1]
["GO:1900048","positive regulation of hemostasis",1,1]
["GO:1900076","regulation of cellular response to insulin stimulus",1,1]
["GO:1900077","negative regulation of cellular response to insulin stimulus",1,1]
["GO:2000021","regulation of ion homeostasis",1,1]
["GO:2000027","regulation of organ morphogenesis",1,1]
["GO:2000106","regulation of leukocyte apoptosis",1,1]
["GO:2000107","negative regulation of leukocyte apoptosis",1,1]
["GO:2000116","regulation of cysteine-type endopeptidase activity",1,1]
["GO:2000117","negative regulation of cysteine-type endopeptidase activity",1,1]
["GO:2000177","regulation of neural precursor cell proliferation",1,1]
["GO:2000179","positive regulation of neural precursor cell proliferation",1,1]
["GO:2000191","regulation of fatty acid transport",1,1]
["GO:2000242","negative regulation of reproductive process",1,1]
["GO:2000273","positive regulation of receptor activity",1,1]
["GO:2000379","positive regulation of reactive oxygen species metabolic process",1,1]
["GO:2000401","regulation of lymphocyte migration",1,1]
["GO:2000514","regulation of CD4-positive, alpha-beta T cell activation",1,1]
["GO:2000516","positive regulation of CD4-positive, alpha-beta T cell activation",1,1]
["GO:2000677","regulation of transcription regulatory region DNA binding",1,1]
["GO:2000736","regulation of stem cell differentiation",1,1]
["GO:2000826","regulation of heart morphogenesis",1,1]
["GO:2001014","regulation of skeletal muscle cell differentiation",1,1]
["GO:2001022","positive regulation of response to DNA damage stimulus",1,1]
["GO:2001056","positive regulation of cysteine-type endopeptidase activity",1,1]
["GO:2001233","regulation of apoptotic signaling pathway",1,1]
["GO:2001235","positive regulation of apoptotic signaling pathway",1,1]
["GO:2001236","regulation of extrinsic apoptotic signaling pathway",1,1]
["GO:2001242","regulation of intrinsic apoptotic signaling pathway",1,1]
["GO:2001244","positive regulation of intrinsic apoptotic signaling pathway",1,1]
["GO:2001257","regulation of cation channel activity",1,1]
["GO:0000118","histone deacetylase complex",1,1]
["GO:0000152","nuclear ubiquitin ligase complex",1,1]
["GO:0000159","protein phosphatase type 2A complex",1,1]
["GO:0000178","exosome (RNase complex)",1,1]
["GO:0000299","integral to membrane of membrane fraction",1,1]
["GO:0000313","organellar ribosome",1,1]
["GO:0000314","organellar small ribosomal subunit",1,1]
["GO:0000315","organellar large ribosomal subunit",1,1]
["GO:0000323","lytic vacuole",1,1]
["GO:0000428","DNA-directed RNA polymerase complex",1,1]
["GO:0000777","condensed chromosome kinetochore",1,1]
["GO:0000779","condensed chromosome, centromeric region",1,1]
["GO:0000784","nuclear chromosome, telomeric region",1,1]
["GO:0000786","nucleosome",1,1]
["GO:0000794","condensed nuclear chromosome",1,1]
["GO:0000795","synaptonemal complex",1,1]
["GO:0000932","cytoplasmic mRNA processing body",1,1]
["GO:0001533","cornified envelope",1,1]
["GO:0001725","stress fiber",1,1]
["GO:0001750","photoreceptor outer segment",1,1]
["GO:0001917","photoreceptor inner segment",1,1]
["GO:0005578","proteinaceous extracellular matrix",1,1]
["GO:0005581","collagen",1,1]
["GO:0005604","basement membrane",1,1]
["GO:0005605","basal lamina",1,1]
["GO:0005637","nuclear inner membrane",1,1]
["GO:0005640","nuclear outer membrane",1,1]
["GO:0005643","nuclear pore",1,1]
["GO:0005680","anaphase-promoting complex",1,1]
["GO:0005689","U12-type spliceosomal complex",1,1]
["GO:0005720","nuclear heterochromatin",1,1]
["GO:0005746","mitochondrial respiratory chain",1,1]
["GO:0005747","mitochondrial respiratory chain complex I",1,1]
["GO:0005753","mitochondrial proton-transporting ATP synthase complex",1,1]
["GO:0005758","mitochondrial intermembrane space",1,1]
["GO:0005761","mitochondrial ribosome",1,1]
["GO:0005762","mitochondrial large ribosomal subunit",1,1]
["GO:0005763","mitochondrial small ribosomal subunit",1,1]
["GO:0005764","lysosome",1,1]
["GO:0005765","lysosomal membrane",1,1]
["GO:0005773","vacuole",1,1]
["GO:0005774","vacuolar membrane",1,1]
["GO:0005775","vacuolar lumen",1,1]
["GO:0005776","autophagic vacuole",1,1]
["GO:0005777","peroxisome",1,1]
["GO:0005778","peroxisomal membrane",1,1]
["GO:0005782","peroxisomal matrix",1,1]
["GO:0005788","endoplasmic reticulum lumen",1,1]
["GO:0005791","rough endoplasmic reticulum",1,1]
["GO:0005793","endoplasmic reticulum-Golgi intermediate compartment",1,1]
["GO:0005795","Golgi stack",1,1]
["GO:0005796","Golgi lumen",1,1]
["GO:0005798","Golgi-associated vesicle",1,1]
["GO:0005801","cis-Golgi network",1,1]
["GO:0005811","lipid particle",1,1]
["GO:0005834","heterotrimeric G-protein complex",1,1]
["GO:0005859","muscle myosin complex",1,1]
["GO:0005871","kinesin complex",1,1]
["GO:0005875","microtubule associated complex",1,1]
["GO:0005902","microvillus",1,1]
["GO:0005903","brush border",1,1]
["GO:0005921","gap junction",1,1]
["GO:0005922","connexon complex",1,1]
["GO:0005929","cilium",1,1]
["GO:0005930","axoneme",1,1]
["GO:0005932","microtubule basal body",1,1]
["GO:0008021","synaptic vesicle",1,1]
["GO:0008076","voltage-gated potassium channel complex",1,1]
["GO:0008180","signalosome",1,1]
["GO:0008305","integrin complex",1,1]
["GO:0008328","ionotropic glutamate receptor complex",1,1]
["GO:0009434","microtubule-based flagellum",1,1]
["GO:0009925","basal plasma membrane",1,1]
["GO:0010494","cytoplasmic stress granule",1,1]
["GO:0014704","intercalated disc",1,1]
["GO:0015935","small ribosomal subunit",1,1]
["GO:0016010","dystrophin-associated glycoprotein complex",1,1]
["GO:0016328","lateral plasma membrane",1,1]
["GO:0016363","nuclear matrix",1,1]
["GO:0016459","myosin complex",1,1]
["GO:0016460","myosin II complex",1,1]
["GO:0016469","proton-transporting two-sector ATPase complex",1,1]
["GO:0016581","NuRD complex",1,1]
["GO:0016592","mediator complex",1,1]
["GO:0019005","SCF ubiquitin ligase complex",1,1]
["GO:0019861","flagellum",1,1]
["GO:0022627","cytosolic small ribosomal subunit",1,1]
["GO:0030018","Z disc",1,1]
["GO:0030057","desmosome",1,1]
["GO:0030117","membrane coat",1,1]
["GO:0030118","clathrin coat",1,1]
["GO:0030119","AP-type membrane coat adaptor complex",1,1]
["GO:0030120","vesicle coat",1,1]
["GO:0030125","clathrin vesicle coat",1,1]
["GO:0030131","clathrin adaptor complex",1,1]
["GO:0030137","COPI-coated vesicle",1,1]
["GO:0030140","trans-Golgi network transport vesicle",1,1]
["GO:0030175","filopodium",1,1]
["GO:0030176","integral to endoplasmic reticulum membrane",1,1]
["GO:0030286","dynein complex",1,1]
["GO:0030315","T-tubule",1,1]
["GO:0030496","midbody",1,1]
["GO:0030530","heterogeneous nuclear ribonucleoprotein complex",1,1]
["GO:0030660","Golgi-associated vesicle membrane",1,1]
["GO:0030663","COPI coated vesicle membrane",1,1]
["GO:0030665","clathrin coated vesicle membrane",1,1]
["GO:0030667","secretory granule membrane",1,1]
["GO:0030669","clathrin-coated endocytic vesicle membrane",1,1]
["GO:0030670","phagocytic vesicle membrane",1,1]
["GO:0030672","synaptic vesicle membrane",1,1]
["GO:0030684","preribosome",1,1]
["GO:0030863","cortical cytoskeleton",1,1]
["GO:0030864","cortical actin cytoskeleton",1,1]
["GO:0030867","rough endoplasmic reticulum membrane",1,1]
["GO:0030880","RNA polymerase complex",1,1]
["GO:0030894","replisome",1,1]
["GO:0030964","NADH dehydrogenase complex",1,1]
["GO:0031012","extracellular matrix",1,1]
["GO:0031091","platelet alpha granule",1,1]
["GO:0031093","platelet alpha granule lumen",1,1]
["GO:0031201","SNARE complex",1,1]
["GO:0031227","intrinsic to endoplasmic reticulum membrane",1,1]
["GO:0031233","intrinsic to external side of plasma membrane",1,1]
["GO:0031362","anchored to external side of plasma membrane",1,1]
["GO:0031513","nonmotile primary cilium",1,1]
["GO:0031519","PcG protein complex",1,1]
["GO:0031526","brush border membrane",1,1]
["GO:0031528","microvillus membrane",1,1]
["GO:0031594","neuromuscular junction",1,1]
["GO:0031902","late endosome membrane",1,1]
["GO:0031903","microbody membrane",1,1]
["GO:0031907","microbody lumen",1,1]
["GO:0031970","organelle envelope lumen",1,1]
["GO:0031983","vesicle lumen",1,1]
["GO:0031984","organelle subcompartment",1,1]
["GO:0031985","Golgi cisterna",1,1]
["GO:0032153","cell division site",1,1]
["GO:0032154","cleavage furrow",1,1]
["GO:0032155","cell division site part",1,1]
["GO:0032391","photoreceptor connecting cilium",1,1]
["GO:0032420","stereocilium",1,1]
["GO:0032421","stereocilium bundle",1,1]
["GO:0032432","actin filament bundle",1,1]
["GO:0032580","Golgi cisterna membrane",1,1]
["GO:0032589","neuron projection membrane",1,1]
["GO:0032592","integral to mitochondrial membrane",1,1]
["GO:0032838","cell projection cytoplasm",1,1]
["GO:0032982","myosin filament",1,1]
["GO:0032993","protein-DNA complex",1,1]
["GO:0032994","protein-lipid complex",1,1]
["GO:0033116","endoplasmic reticulum-Golgi intermediate compartment membrane",1,1]
["GO:0033176","proton-transporting V-type ATPase complex",1,1]
["GO:0033177","proton-transporting two-sector ATPase complex, proton-transporting domain",1,1]
["GO:0033178","proton-transporting two-sector ATPase complex, catalytic domain",1,1]
["GO:0034358","plasma lipoprotein particle",1,1]
["GO:0034361","very-low-density lipoprotein particle",1,1]
["GO:0034364","high-density lipoprotein particle",1,1]
["GO:0034385","triglyceride-rich lipoprotein particle",1,1]
["GO:0034399","nuclear periphery",1,1]
["GO:0034705","potassium channel complex",1,1]
["GO:0034706","sodium channel complex",1,1]
["GO:0034707","chloride channel complex",1,1]
["GO:0034774","secretory granule lumen",1,1]
["GO:0035085","cilium axoneme",1,1]
["GO:0035267","NuA4 histone acetyltransferase complex",1,1]
["GO:0035770","ribonucleoprotein granule",1,1]
["GO:0035869","ciliary transition zone",1,1]
["GO:0042383","sarcolemma",1,1]
["GO:0042579","microbody",1,1]
["GO:0042611","MHC protein complex",1,1]
["GO:0042612","MHC class I protein complex",1,1]
["GO:0042613","MHC class II protein complex",1,1]
["GO:0043073","germ cell nucleus",1,1]
["GO:0043189","H4/H2A histone acetyltransferase complex",1,1]
["GO:0043195","terminal button",1,1]
["GO:0043202","lysosomal lumen",1,1]
["GO:0043204","perikaryon",1,1]
["GO:0043601","nuclear replisome",1,1]
["GO:0044291","cell-cell contact zone",1,1]
["GO:0044304","main axon",1,1]
["GO:0044420","extracellular matrix part",1,1]
["GO:0044437","vacuolar part",1,1]
["GO:0044438","microbody part",1,1]
["GO:0044439","peroxisomal part",1,1]
["GO:0044441","cilium part",1,1]
["GO:0044442","microtubule-based flagellum part",1,1]
["GO:0044447","axoneme part",1,1]
["GO:0044448","cell cortex part",1,1]
["GO:0044452","nucleolar part",1,1]
["GO:0044460","flagellum part",1,1]
["GO:0045095","keratin filament",1,1]
["GO:0045178","basal part of cell",1,1]
["GO:0045259","proton-transporting ATP synthase complex",1,1]
["GO:0045271","respiratory chain complex I",1,1]
["GO:0045334","clathrin-coated endocytic vesicle",1,1]
["GO:0046658","anchored to plasma membrane",1,1]
["GO:0046930","pore complex",1,1]
["GO:0048475","coated membrane",1,1]
["GO:0055029","nuclear DNA-directed RNA polymerase complex",1,1]
["GO:0055037","recycling endosome",1,1]
["GO:0055038","recycling endosome membrane",1,1]
["GO:0060170","cilium membrane",1,1]
["GO:0060205","cytoplasmic membrane-bounded vesicle lumen",1,1]
["GO:0070469","respiratory chain",1,1]
["GO:0072372","primary cilium",1,1]
["GO:0080008","CUL4 RING ubiquitin ligase complex",1,1]
["GO:0000030","mannosyltransferase activity",1,1]
["GO:0000049","tRNA binding",1,1]
["GO:0000146","microfilament motor activity",1,1]
["GO:0000977","RNA polymerase II regulatory region sequence-specific DNA binding",1,1]
["GO:0000978","RNA polymerase II core promoter proximal region sequence-specific DNA binding",1,1]
["GO:0000979","RNA polymerase II core promoter sequence-specific DNA binding",1,1]
["GO:0000982","RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity",1,1]
["GO:0001012","RNA polymerase II regulatory region DNA binding",1,1]
["GO:0001077","RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription",1,1]
["GO:0001078","RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription",1,1]
["GO:0001085","RNA polymerase II transcription factor binding",1,1]
["GO:0001102","RNA polymerase II activating transcription factor binding",1,1]
["GO:0001106","RNA polymerase II transcription corepressor activity",1,1]
["GO:0001158","enhancer sequence-specific DNA binding",1,1]
["GO:0001191","RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription",1,1]
["GO:0001608","G-protein coupled nucleotide receptor activity",1,1]
["GO:0001614","purinergic nucleotide receptor activity",1,1]
["GO:0001637","G-protein coupled chemoattractant receptor activity",1,1]
["GO:0001664","G-protein coupled receptor binding",1,1]
["GO:0001871","pattern binding",1,1]
["GO:0001882","nucleoside binding",1,1]
["GO:0001968","fibronectin binding",1,1]
["GO:0002020","protease binding",1,1]
["GO:0003684","damaged DNA binding",1,1]
["GO:0003690","double-stranded DNA binding",1,1]
["GO:0003697","single-stranded DNA binding",1,1]
["GO:0003724","RNA helicase activity",1,1]
["GO:0003729","mRNA binding",1,1]
["GO:0003730","mRNA 3'-UTR binding",1,1]
["GO:0003743","translation initiation factor activity",1,1]
["GO:0003746","translation elongation factor activity",1,1]
["GO:0003755","peptidyl-prolyl cis-trans isomerase activity",1,1]
["GO:0003774","motor activity",1,1]
["GO:0003777","microtubule motor activity",1,1]
["GO:0003823","antigen binding",1,1]
["GO:0003887","DNA-directed DNA polymerase activity",1,1]
["GO:0003899","DNA-directed RNA polymerase activity",1,1]
["GO:0003950","NAD+ ADP-ribosyltransferase activity",1,1]
["GO:0003954","NADH dehydrogenase activity",1,1]
["GO:0003995","acyl-CoA dehydrogenase activity",1,1]
["GO:0004004","ATP-dependent RNA helicase activity",1,1]
["GO:0004012","phospholipid-translocating ATPase activity",1,1]
["GO:0004033","aldo-keto reductase (NADP) activity",1,1]
["GO:0004091","carboxylesterase activity",1,1]
["GO:0004112","cyclic-nucleotide phosphodiesterase activity",1,1]
["GO:0004114","3',5'-cyclic-nucleotide phosphodiesterase activity",1,1]
["GO:0004129","cytochrome-c oxidase activity",1,1]
["GO:0004143","diacylglycerol kinase activity",1,1]
["GO:0004177","aminopeptidase activity",1,1]
["GO:0004180","carboxypeptidase activity",1,1]
["GO:0004181","metallocarboxypeptidase activity",1,1]
["GO:0004190","aspartic-type endopeptidase activity",1,1]
["GO:0004197","cysteine-type endopeptidase activity",1,1]
["GO:0004198","calcium-dependent cysteine-type endopeptidase activity",1,1]
["GO:0004221","ubiquitin thiolesterase activity",1,1]
["GO:0004252","serine-type endopeptidase activity",1,1]
["GO:0004364","glutathione transferase activity",1,1]
["GO:0004407","histone deacetylase activity",1,1]
["GO:0004520","endodeoxyribonuclease activity",1,1]
["GO:0004527","exonuclease activity",1,1]
["GO:0004532","exoribonuclease activity",1,1]
["GO:0004536","deoxyribonuclease activity",1,1]
["GO:0004553","hydrolase activity, hydrolyzing O-glycosyl compounds",1,1]
["GO:0004601","peroxidase activity",1,1]
["GO:0004623","phospholipase A2 activity",1,1]
["GO:0004653","polypeptide N-acetylgalactosaminyltransferase activity",1,1]
["GO:0004675","transmembrane receptor protein serine/threonine kinase activity",1,1]
["GO:0004697","protein kinase C activity",1,1]
["GO:0004709","MAP kinase kinase kinase activity",1,1]
["GO:0004714","transmembrane receptor protein tyrosine kinase activity",1,1]
["GO:0004806","triglyceride lipase activity",1,1]
["GO:0004812","aminoacyl-tRNA ligase activity",1,1]
["GO:0004843","ubiquitin-specific protease activity",1,1]
["GO:0004864","protein phosphatase inhibitor activity",1,1]
["GO:0004866","endopeptidase inhibitor activity",1,1]
["GO:0004867","serine-type endopeptidase inhibitor activity",1,1]
["GO:0004869","cysteine-type endopeptidase inhibitor activity",1,1]
["GO:0004890","GABA-A receptor activity",1,1]
["GO:0004950","chemokine receptor activity",1,1]
["GO:0004984","olfactory receptor activity",1,1]
["GO:0005003","ephrin receptor activity",1,1]
["GO:0005024","transforming growth factor beta-activated receptor activity",1,1]
["GO:0005044","scavenger receptor activity",1,1]
["GO:0005048","signal sequence binding",1,1]
["GO:0005085","guanyl-nucleotide exchange factor activity",1,1]
["GO:0005086","ARF guanyl-nucleotide exchange factor activity",1,1]
["GO:0005088","Ras guanyl-nucleotide exchange factor activity",1,1]
["GO:0005089","Rho guanyl-nucleotide exchange factor activity",1,1]
["GO:0005100","Rho GTPase activator activity",1,1]
["GO:0005104","fibroblast growth factor receptor binding",1,1]
["GO:0005109","frizzled binding",1,1]
["GO:0005125","cytokine activity",1,1]
["GO:0005126","cytokine receptor binding",1,1]
["GO:0005154","epidermal growth factor receptor binding",1,1]
["GO:0005158","insulin receptor binding",1,1]
["GO:0005160","transforming growth factor beta receptor binding",1,1]
["GO:0005164","tumor necrosis factor receptor binding",1,1]
["GO:0005178","integrin binding",1,1]
["GO:0005179","hormone activity",1,1]
["GO:0005184","neuropeptide hormone activity",1,1]
["GO:0005200","structural constituent of cytoskeleton",1,1]
["GO:0005201","extracellular matrix structural constituent",1,1]
["GO:0005212","structural constituent of eye lens",1,1]
["GO:0005217","intracellular ligand-gated ion channel activity",1,1]
["GO:0005227","calcium activated cation channel activity",1,1]
["GO:0005242","inward rectifier potassium channel activity",1,1]
["GO:0005247","voltage-gated chloride channel activity",1,1]
["GO:0005248","voltage-gated sodium channel activity",1,1]
["GO:0005253","anion channel activity",1,1]
["GO:0005254","chloride channel activity",1,1]
["GO:0005272","sodium channel activity",1,1]
["GO:0005275","amine transmembrane transporter activity",1,1]
["GO:0005310","dicarboxylic acid transmembrane transporter activity",1,1]
["GO:0005326","neurotransmitter transporter activity",1,1]
["GO:0005328","neurotransmitter:sodium symporter activity",1,1]
["GO:0005342","organic acid transmembrane transporter activity",1,1]
["GO:0005343","organic acid:sodium symporter activity",1,1]
["GO:0005484","SNAP receptor activity",1,1]
["GO:0005501","retinoid binding",1,1]
["GO:0005507","copper ion binding",1,1]
["GO:0005518","collagen binding",1,1]
["GO:0005520","insulin-like growth factor binding",1,1]
["GO:0005523","tropomyosin binding",1,1]
["GO:0005527","macrolide binding",1,1]
["GO:0005528","FK506 binding",1,1]
["GO:0005529","sugar binding",1,1]
["GO:0005537","mannose binding",1,1]
["GO:0005539","glycosaminoglycan binding",1,1]
["GO:0005540","hyaluronic acid binding",1,1]
["GO:0005542","folic acid binding",1,1]
["GO:0005544","calcium-dependent phospholipid binding",1,1]
["GO:0008009","chemokine activity",1,1]
["GO:0008013","beta-catenin binding",1,1]
["GO:0008028","monocarboxylic acid transmembrane transporter activity",1,1]
["GO:0008083","growth factor activity",1,1]
["GO:0008093","cytoskeletal adaptor activity",1,1]
["GO:0008135","translation factor activity, nucleic acid binding",1,1]
["GO:0008137","NADH dehydrogenase (ubiquinone) activity",1,1]
["GO:0008138","protein tyrosine/serine/threonine phosphatase activity",1,1]
["GO:0008146","sulfotransferase activity",1,1]
["GO:0008186","RNA-dependent ATPase activity",1,1]
["GO:0008200","ion channel inhibitor activity",1,1]
["GO:0008201","heparin binding",1,1]
["GO:0008227","G-protein coupled amine receptor activity",1,1]
["GO:0008234","cysteine-type peptidase activity",1,1]
["GO:0008235","metalloexopeptidase activity",1,1]
["GO:0008301","DNA binding, bending",1,1]
["GO:0008307","structural constituent of muscle",1,1]
["GO:0008308","voltage-gated anion channel activity",1,1]
["GO:0008320","protein transmembrane transporter activity",1,1]
["GO:0008353","RNA polymerase II carboxy-terminal domain kinase activity",1,1]
["GO:0008373","sialyltransferase activity",1,1]
["GO:0008374","O-acyltransferase activity",1,1]
["GO:0008376","acetylgalactosaminyltransferase activity",1,1]
["GO:0008378","galactosyltransferase activity",1,1]
["GO:0008408","3'-5' exonuclease activity",1,1]
["GO:0008483","transaminase activity",1,1]
["GO:0008484","sulfuric ester hydrolase activity",1,1]
["GO:0008527","taste receptor activity",1,1]
["GO:0008565","protein transporter activity",1,1]
["GO:0008601","protein phosphatase type 2A regulator activity",1,1]
["GO:0008603","cAMP-dependent protein kinase regulator activity",1,1]
["GO:0008656","cysteine-type endopeptidase activator activity involved in apoptotic process",1,1]
["GO:0009975","cyclase activity",1,1]
["GO:0015002","heme-copper terminal oxidase activity",1,1]
["GO:0015020","glucuronosyltransferase activity",1,1]
["GO:0015026","coreceptor activity",1,1]
["GO:0015035","protein disulfide oxidoreductase activity",1,1]
["GO:0015036","disulfide oxidoreductase activity",1,1]
["GO:0015078","hydrogen ion transmembrane transporter activity",1,1]
["GO:0015081","sodium ion transmembrane transporter activity",1,1]
["GO:0015085","calcium ion transmembrane transporter activity",1,1]
["GO:0015103","inorganic anion transmembrane transporter activity",1,1]
["GO:0015144","carbohydrate transmembrane transporter activity",1,1]
["GO:0015145","monosaccharide transmembrane transporter activity",1,1]
["GO:0015171","amino acid transmembrane transporter activity",1,1]
["GO:0015175","neutral amino acid transmembrane transporter activity",1,1]
["GO:0015179","L-amino acid transmembrane transporter activity",1,1]
["GO:0015269","calcium-activated potassium channel activity",1,1]
["GO:0015278","calcium-release channel activity",1,1]
["GO:0015291","secondary active transmembrane transporter activity",1,1]
["GO:0015293","symporter activity",1,1]
["GO:0015294","solute:cation symporter activity",1,1]
["GO:0015296","anion:cation symporter activity",1,1]
["GO:0015297","antiporter activity",1,1]
["GO:0015298","solute:cation antiporter activity",1,1]
["GO:0015299","solute:hydrogen antiporter activity",1,1]
["GO:0015300","solute:solute antiporter activity",1,1]
["GO:0015301","anion:anion antiporter activity",1,1]
["GO:0015370","solute:sodium symporter activity",1,1]
["GO:0015399","primary active transmembrane transporter activity",1,1]
["GO:0015405","P-P-bond-hydrolysis-driven transmembrane transporter activity",1,1]
["GO:0015459","potassium channel regulator activity",1,1]
["GO:0015491","cation:cation antiporter activity",1,1]
["GO:0015662","ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism",1,1]
["GO:0015932","nucleobase-containing compound transmembrane transporter activity",1,1]
["GO:0016208","AMP binding",1,1]
["GO:0016229","steroid dehydrogenase activity",1,1]
["GO:0016248","channel inhibitor activity",1,1]
["GO:0016289","CoA hydrolase activity",1,1]
["GO:0016409","palmitoyltransferase activity",1,1]
["GO:0016502","nucleotide receptor activity",1,1]
["GO:0016504","peptidase activator activity",1,1]
["GO:0016505","apoptotic protease activator activity",1,1]
["GO:0016614","oxidoreductase activity, acting on CH-OH group of donors",1,1]
["GO:0016616","oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",1,1]
["GO:0016620","oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor",1,1]
["GO:0016627","oxidoreductase activity, acting on the CH-CH group of donors",1,1]
["GO:0016628","oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor",1,1]
["GO:0016638","oxidoreductase activity, acting on the CH-NH2 group of donors",1,1]
["GO:0016645","oxidoreductase activity, acting on the CH-NH group of donors",1,1]
["GO:0016646","oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor",1,1]
["GO:0016651","oxidoreductase activity, acting on NADH or NADPH",1,1]
["GO:0016655","oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor",1,1]
["GO:0016667","oxidoreductase activity, acting on a sulfur group of donors",1,1]
["GO:0016675","oxidoreductase activity, acting on a heme group of donors",1,1]
["GO:0016676","oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor",1,1]
["GO:0016684","oxidoreductase activity, acting on peroxide as acceptor",1,1]
["GO:0016701","oxidoreductase activity, acting on single donors with incorporation of molecular oxygen",1,1]
["GO:0016702","oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen",1,1]
["GO:0016706","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",1,1]
["GO:0016712","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen",1,1]
["GO:0016755","transferase activity, transferring amino-acyl groups",1,1]
["GO:0016763","transferase activity, transferring pentosyl groups",1,1]
["GO:0016765","transferase activity, transferring alkyl or aryl (other than methyl) groups",1,1]
["GO:0016769","transferase activity, transferring nitrogenous groups",1,1]
["GO:0016776","phosphotransferase activity, phosphate group as acceptor",1,1]
["GO:0016780","phosphotransferase activity, for other substituted phosphate groups",1,1]
["GO:0016782","transferase activity, transferring sulfur-containing groups",1,1]
["GO:0016790","thiolester hydrolase activity",1,1]
["GO:0016796","exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters",1,1]
["GO:0016798","hydrolase activity, acting on glycosyl bonds",1,1]
["GO:0016799","hydrolase activity, hydrolyzing N-glycosyl compounds",1,1]
["GO:0016810","hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds",1,1]
["GO:0016811","hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides",1,1]
["GO:0016814","hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines",1,1]
["GO:0016820","hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances",1,1]
["GO:0016830","carbon-carbon lyase activity",1,1]
["GO:0016831","carboxy-lyase activity",1,1]
["GO:0016849","phosphorus-oxygen lyase activity",1,1]
["GO:0016853","isomerase activity",1,1]
["GO:0016859","cis-trans isomerase activity",1,1]
["GO:0016860","intramolecular oxidoreductase activity",1,1]
["GO:0016866","intramolecular transferase activity",1,1]
["GO:0016875","ligase activity, forming carbon-oxygen bonds",1,1]
["GO:0016876","ligase activity, forming aminoacyl-tRNA and related compounds",1,1]
["GO:0016877","ligase activity, forming carbon-sulfur bonds",1,1]
["GO:0016878","acid-thiol ligase activity",1,1]
["GO:0016891","endoribonuclease activity, producing 5'-phosphomonoesters",1,1]
["GO:0016893","endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters",1,1]
["GO:0016903","oxidoreductase activity, acting on the aldehyde or oxo group of donors",1,1]
["GO:0016917","GABA receptor activity",1,1]
["GO:0016922","ligand-dependent nuclear receptor binding",1,1]
["GO:0017022","myosin binding",1,1]
["GO:0017046","peptide hormone binding",1,1]
["GO:0017134","fibroblast growth factor binding",1,1]
["GO:0017147","Wnt-protein binding",1,1]
["GO:0019199","transmembrane receptor protein kinase activity",1,1]
["GO:0019200","carbohydrate kinase activity",1,1]
["GO:0019201","nucleotide kinase activity",1,1]
["GO:0019205","nucleobase-containing compound kinase activity",1,1]
["GO:0019209","kinase activator activity",1,1]
["GO:0019212","phosphatase inhibitor activity",1,1]
["GO:0019213","deacetylase activity",1,1]
["GO:0019239","deaminase activity",1,1]
["GO:0019783","small conjugating protein-specific protease activity",1,1]
["GO:0019829","cation-transporting ATPase activity",1,1]
["GO:0019838","growth factor binding",1,1]
["GO:0019840","isoprenoid binding",1,1]
["GO:0019843","rRNA binding",1,1]
["GO:0019865","immunoglobulin binding",1,1]
["GO:0019888","protein phosphatase regulator activity",1,1]
["GO:0019894","kinesin binding",1,1]
["GO:0022804","active transmembrane transporter activity",1,1]
["GO:0022829","wide pore channel activity",1,1]
["GO:0022839","ion gated channel activity",1,1]
["GO:0022884","macromolecule transmembrane transporter activity",1,1]
["GO:0030228","lipoprotein particle receptor activity",1,1]
["GO:0030246","carbohydrate binding",1,1]
["GO:0030247","polysaccharide binding",1,1]
["GO:0030295","protein kinase activator activity",1,1]
["GO:0030331","estrogen receptor binding",1,1]
["GO:0030374","ligand-dependent nuclear receptor transcription coactivator activity",1,1]
["GO:0030414","peptidase inhibitor activity",1,1]
["GO:0030551","cyclic nucleotide binding",1,1]
["GO:0030552","cAMP binding",1,1]
["GO:0030971","receptor tyrosine kinase binding",1,1]
["GO:0030983","mismatched DNA binding",1,1]
["GO:0031418","L-ascorbic acid binding",1,1]
["GO:0031435","mitogen-activated protein kinase kinase kinase binding",1,1]
["GO:0031593","polyubiquitin binding",1,1]
["GO:0031683","G-protein beta/gamma-subunit complex binding",1,1]
["GO:0032182","small conjugating protein binding",1,1]
["GO:0032393","MHC class I receptor activity",1,1]
["GO:0032451","demethylase activity",1,1]
["GO:0032452","histone demethylase activity",1,1]
["GO:0032813","tumor necrosis factor receptor superfamily binding",1,1]
["GO:0033558","protein deacetylase activity",1,1]
["GO:0033613","activating transcription factor binding",1,1]
["GO:0033764","steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",1,1]
["GO:0034061","DNA polymerase activity",1,1]
["GO:0034062","RNA polymerase activity",1,1]
["GO:0035035","histone acetyltransferase binding",1,1]
["GO:0035250","UDP-galactosyltransferase activity",1,1]
["GO:0035258","steroid hormone receptor binding",1,1]
["GO:0035326","enhancer binding",1,1]
["GO:0035586","purinergic receptor activity",1,1]
["GO:0038024","cargo receptor activity",1,1]
["GO:0042056","chemoattractant activity",1,1]
["GO:0042162","telomeric DNA binding",1,1]
["GO:0042169","SH2 domain binding",1,1]
["GO:0042287","MHC protein binding",1,1]
["GO:0042379","chemokine receptor binding",1,1]
["GO:0042562","hormone binding",1,1]
["GO:0042605","peptide antigen binding",1,1]
["GO:0042625","ATPase activity, coupled to transmembrane movement of ions",1,1]
["GO:0042626","ATPase activity, coupled to transmembrane movement of substances",1,1]
["GO:0042805","actinin binding",1,1]
["GO:0042813","Wnt-activated receptor activity",1,1]
["GO:0042974","retinoic acid receptor binding",1,1]
["GO:0043014","alpha-tubulin binding",1,1]
["GO:0043015","gamma-tubulin binding",1,1]
["GO:0043021","ribonucleoprotein complex binding",1,1]
["GO:0043022","ribosome binding",1,1]
["GO:0043027","cysteine-type endopeptidase inhibitor activity involved in apoptotic process",1,1]
["GO:0043028","cysteine-type endopeptidase regulator activity involved in apoptotic process",1,1]
["GO:0043130","ubiquitin binding",1,1]
["GO:0043168","anion binding",1,1]
["GO:0043178","alcohol binding",1,1]
["GO:0043236","laminin binding",1,1]
["GO:0043425","bHLH transcription factor binding",1,1]
["GO:0043492","ATPase activity, coupled to movement of substances",1,1]
["GO:0043498","cell surface binding",1,1]
["GO:0043499","eukaryotic cell surface binding",1,1]
["GO:0043531","ADP binding",1,1]
["GO:0043621","protein self-association",1,1]
["GO:0044325","ion channel binding",1,1]
["GO:0045028","G-protein coupled purinergic nucleotide receptor activity",1,1]
["GO:0045182","translation regulator activity",1,1]
["GO:0045296","cadherin binding",1,1]
["GO:0046915","transition metal ion transmembrane transporter activity",1,1]
["GO:0046933","hydrogen ion transporting ATP synthase activity, rotational mechanism",1,1]
["GO:0046943","carboxylic acid transmembrane transporter activity",1,1]
["GO:0046961","proton-transporting ATPase activity, rotational mechanism",1,1]
["GO:0048020","CCR chemokine receptor binding",1,1]
["GO:0048029","monosaccharide binding",1,1]
["GO:0048487","beta-tubulin binding",1,1]
["GO:0050136","NADH dehydrogenase (quinone) activity",1,1]
["GO:0050253","retinyl-palmitate esterase activity",1,1]
["GO:0050661","NADP binding",1,1]
["GO:0050664","oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor",1,1]
["GO:0050681","androgen receptor binding",1,1]
["GO:0050699","WW domain binding",1,1]
["GO:0050840","extracellular matrix binding",1,1]
["GO:0051018","protein kinase A binding",1,1]
["GO:0051059","NF-kappaB binding",1,1]
["GO:0051082","unfolded protein binding",1,1]
["GO:0051117","ATPase binding",1,1]
["GO:0051119","sugar transmembrane transporter activity",1,1]
["GO:0051183","vitamin transporter activity",1,1]
["GO:0051213","dioxygenase activity",1,1]
["GO:0051287","NAD binding",1,1]
["GO:0051536","iron-sulfur cluster binding",1,1]
["GO:0051537","2 iron, 2 sulfur cluster binding",1,1]
["GO:0051539","4 iron, 4 sulfur cluster binding",1,1]
["GO:0051540","metal cluster binding",1,1]
["GO:0051635","bacterial cell surface binding",1,1]
["GO:0051721","protein phosphatase 2A binding",1,1]
["GO:0051861","glycolipid binding",1,1]
["GO:0051879","Hsp90 protein binding",1,1]
["GO:0052689","carboxylic ester hydrolase activity",1,1]
["GO:0055102","lipase inhibitor activity",1,1]
["GO:0061134","peptidase regulator activity",1,1]
["GO:0061135","endopeptidase regulator activity",1,1]
["GO:0070001","aspartic-type peptidase activity",1,1]
["GO:0070325","lipoprotein particle receptor binding",1,1]
["GO:0070330","aromatase activity",1,1]
["GO:0070412","R-SMAD binding",1,1]
["GO:0070851","growth factor receptor binding",1,1]
["GO:0070888","E-box binding",1,1]
["GO:0071813","lipoprotein particle binding",1,1]
["GO:0071814","protein-lipid complex binding",1,1]
["GO:0071855","neuropeptide receptor binding",1,1]
["GO:0072509","divalent inorganic cation transmembrane transporter activity",1,1]
["REACT:5","REACT: A tetrasaccharide linker sequence is required for GAG synthesis",1,1]
["REACT:7","REACT: ABC-family proteins mediated transport",1,1]
["REACT:8","REACT: ABCA transporters in lipid homeostasis",1,1]
["REACT:11","REACT: ADP signalling through P2Y purinoceptor 1",1,1]
["REACT:12","REACT: ADP signalling through P2Y purinoceptor 12",1,1]
["REACT:17","REACT: APC-Cdc20 mediated degradation of Nek2A",1,1]
["REACT:19","REACT: APC/C:Cdc20 mediated degradation of Cyclin B",1,1]
["REACT:32","REACT: Abortive elongation of HIV-1 transcript in the absence of Tat",1,1]
["REACT:37","REACT: Activated NOTCH1 Transmits Signal to the Nucleus",1,1]
["REACT:39","REACT: Activated point mutants of FGFR2",1,1]
["REACT:52","REACT: Activation of Chaperone Genes by XBP1(S)",1,1]
["REACT:54","REACT: Activation of Chaperones by IRE1alpha",1,1]
["REACT:56","REACT: Activation of G protein gated Potassium channels",1,1]
["REACT:57","REACT: Activation of GABAB receptors",1,1]
["REACT:58","REACT: Activation of Genes by ATF4",1,1]
["REACT:61","REACT: Activation of Matrix Metalloproteinases",1,1]
["REACT:75","REACT: Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S",1,1]
["REACT:81","REACT: Acyl chain remodelling of PC",1,1]
["REACT:82","REACT: Acyl chain remodelling of PE",1,1]
["REACT:83","REACT: Acyl chain remodelling of PG",1,1]
["REACT:84","REACT: Acyl chain remodelling of PI",1,1]
["REACT:85","REACT: Acyl chain remodelling of PS",1,1]
["REACT:90","REACT: Adherens junctions interactions",1,1]
["REACT:99","REACT: Amine compound SLC transporters",1,1]
["REACT:100","REACT: Amine ligand-binding receptors",1,1]
["REACT:101","REACT: Amine-derived hormones",1,1]
["REACT:103","REACT: Amino acid and oligopeptide SLC transporters",1,1]
["REACT:104","REACT: Amino acid synthesis and interconversion (transamination)",1,1]
["REACT:105","REACT: Amino acid transport across the plasma membrane",1,1]
["REACT:108","REACT: Amyloids",1,1]
["REACT:110","REACT: Antigen Activates B Cell Receptor Leading to Generation of Second Messengers",1,1]
["REACT:111","REACT: Antigen Presentation: Folding, assembly and peptide loading of class I MHC",1,1]
["REACT:118","REACT: Apoptotic cleavage of cellular proteins",1,1]
["REACT:119","REACT: Apoptotic execution  phase",1,1]
["REACT:121","REACT: Aquaporin-mediated transport",1,1]
["REACT:124","REACT: Asparagine N-linked glycosylation",1,1]
["REACT:131","REACT: Association of TriC/CCT with target proteins during biosynthesis",1,1]
["REACT:132","REACT: Association of licensing factors with the pre-replicative complex",1,1]
["REACT:142","REACT: BMAL1:CLOCK/NPAS2 Activates Circadian Expression",1,1]
["REACT:143","REACT: Base Excision Repair",1,1]
["REACT:146","REACT: Basigin interactions",1,1]
["REACT:147","REACT: Beta defensins",1,1]
["REACT:155","REACT: Beta-catenin phosphorylation cascade",1,1]
["REACT:164","REACT: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein",1,1]
["REACT:168","REACT: Botulinum neurotoxicity",1,1]
["REACT:173","REACT: CD28 co-stimulation",1,1]
["REACT:174","REACT: CD28 dependent PI3K/Akt signaling",1,1]
["REACT:189","REACT: CRMPs in Sema3A signaling",1,1]
["REACT:191","REACT: CTLA4 inhibitory signaling",1,1]
["REACT:193","REACT: Ca-dependent events",1,1]
["REACT:195","REACT: CaM pathway",1,1]
["REACT:198","REACT: Calmodulin induced events",1,1]
["REACT:222","REACT: Chaperonin-mediated protein folding",1,1]
["REACT:223","REACT: Chemokine receptors bind chemokines",1,1]
["REACT:225","REACT: Cholesterol biosynthesis",1,1]
["REACT:226","REACT: Chondroitin sulfate biosynthesis",1,1]
["REACT:227","REACT: Chondroitin sulfate/dermatan sulfate metabolism",1,1]
["REACT:228","REACT: Chromosome Maintenance",1,1]
["REACT:229","REACT: Chylomicron-mediated lipid transport",1,1]
["REACT:231","REACT: Circadian Repression of Expression by REV-ERBA",1,1]
["REACT:232","REACT: Citric acid cycle (TCA cycle)",1,1]
["REACT:234","REACT: Class B/2 (Secretin family receptors)",1,1]
["REACT:235","REACT: Class C/3 (Metabotropic glutamate/pheromone receptors)",1,1]
["REACT:239","REACT: Classical antibody-mediated complement activation",1,1]
["REACT:241","REACT: Cleavage of Growing Transcript in the Termination Region",1,1]
["REACT:245","REACT: Collagen biosynthesis and modifying enzymes",1,1]
["REACT:246","REACT: Collagen formation",1,1]
["REACT:248","REACT: Complement cascade",1,1]
["REACT:253","REACT: Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase",1,1]
["REACT:254","REACT: Cooperation of Prefoldin and TriC/CCT  in actin and tubulin folding",1,1]
["REACT:255","REACT: Costimulation by the CD28 family",1,1]
["REACT:257","REACT: Creation of C4 and C2 activators",1,1]
["REACT:260","REACT: Cyclin A/B1 associated events during G2/M transition",1,1]
["REACT:271","REACT: Cytosolic tRNA aminoacylation",1,1]
["REACT:272","REACT: DAG and IP3 signaling",1,1]
["REACT:283","REACT: DNA strand elongation",1,1]
["REACT:285","REACT: Deadenylation of mRNA",1,1]
["REACT:286","REACT: Deadenylation-dependent mRNA decay",1,1]
["REACT:288","REACT: Defensins",1,1]
["REACT:292","REACT: Degradation of the extracellular matrix",1,1]
["REACT:294","REACT: Deposition of New CENPA-containing Nucleosomes at the Centromere",1,1]
["REACT:299","REACT: Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)",1,1]
["REACT:301","REACT: Destabilization of mRNA by Tristetraprolin (TTP)",1,1]
["REACT:303","REACT: Diabetes pathways",1,1]
["REACT:313","REACT: Double-Strand Break Repair",1,1]
["REACT:317","REACT: Downregulation of TGF-beta receptor signaling",1,1]
["REACT:322","REACT: Dual incision reaction in GG-NER",1,1]
["REACT:324","REACT: E2F mediated regulation of DNA replication",1,1]
["REACT:327","REACT: EGFR downregulation",1,1]
["REACT:328","REACT: EGFR interacts with phospholipase C-gamma",1,1]
["REACT:337","REACT: Early Phase of HIV Life Cycle",1,1]
["REACT:338","REACT: Effects of PIP2 hydrolysis",1,1]
["REACT:339","REACT: Eicosanoid ligand-binding receptors",1,1]
["REACT:343","REACT: Elongation arrest and recovery",1,1]
["REACT:345","REACT: Endosomal Sorting Complex Required For Transport (ESCRT)",1,1]
["REACT:356","REACT: Export of Viral Ribonucleoproteins from Nucleus",1,1]
["REACT:357","REACT: Extension of Telomeres",1,1]
["REACT:358","REACT: Extracellular matrix organization",1,1]
["REACT:361","REACT: FGFR ligand binding and activation",1,1]
["REACT:366","REACT: FGFR2 ligand binding and activation",1,1]
["REACT:377","REACT: Fanconi Anemia pathway",1,1]
["REACT:379","REACT: Fatty Acyl-CoA Biosynthesis",1,1]
["REACT:383","REACT: Formation of ATP by chemiosmotic coupling",1,1]
["REACT:384","REACT: Formation of Fibrin Clot (Clotting Cascade)",1,1]
["REACT:385","REACT: Formation of HIV-1 elongation complex containing HIV-1 Tat",1,1]
["REACT:386","REACT: Formation of HIV-1 elongation complex in the absence of HIV-1 Tat",1,1]
["REACT:388","REACT: Formation of RNA Pol II elongation complex",1,1]
["REACT:393","REACT: Formation of incision complex in GG-NER",1,1]
["REACT:394","REACT: Formation of the Early Elongation Complex",1,1]
["REACT:396","REACT: Formation of the HIV-1 Early Elongation Complex",1,1]
["REACT:398","REACT: Formation of the ternary complex, and subsequently, the 43S complex",1,1]
["REACT:400","REACT: Formation of tubulin folding intermediates by CCT/TriC",1,1]
["REACT:407","REACT: G alpha (12/13) signalling events",1,1]
["REACT:410","REACT: G alpha (s) signalling events",1,1]
["REACT:411","REACT: G alpha (z) signalling events",1,1]
["REACT:412","REACT: G beta:gamma signalling through PI3Kgamma",1,1]
["REACT:414","REACT: G protein gated Potassium channels",1,1]
["REACT:415","REACT: G-protein activation",1,1]
["REACT:422","REACT: G1/S-Specific Transcription",1,1]
["REACT:428","REACT: GAB1 signalosome",1,1]
["REACT:431","REACT: GABA B receptor activation",1,1]
["REACT:432","REACT: GABA receptor activation",1,1]
["REACT:441","REACT: GRB2:SOS provides linkage to MAPK signaling for Intergrins",1,1]
["REACT:447","REACT: Gap junction assembly",1,1]
["REACT:449","REACT: Gap junction trafficking",1,1]
["REACT:450","REACT: Gap junction trafficking and regulation",1,1]
["REACT:451","REACT: Gap-filling DNA repair synthesis and ligation in GG-NER",1,1]
["REACT:452","REACT: Gap-filling DNA repair synthesis and ligation in TC-NER",1,1]
["REACT:455","REACT: Generation of second messenger molecules",1,1]
["REACT:457","REACT: Global Genomic NER (GG-NER)",1,1]
["REACT:458","REACT: Glucagon signaling in metabolic regulation",1,1]
["REACT:459","REACT: Glucagon-type ligand receptors",1,1]
["REACT:461","REACT: Gluconeogenesis",1,1]
["REACT:462","REACT: Glucose metabolism",1,1]
["REACT:463","REACT: Glucose transport",1,1]
["REACT:464","REACT: Glucuronidation",1,1]
["REACT:467","REACT: Glutathione conjugation",1,1]
["REACT:472","REACT: Glycolysis",1,1]
["REACT:474","REACT: Glycosaminoglycan metabolism",1,1]
["REACT:475","REACT: Glycosphingolipid metabolism",1,1]
["REACT:485","REACT: HIV-1 Transcription Elongation",1,1]
["REACT:487","REACT: HIV-1 elongation arrest and recovery",1,1]
["REACT:488","REACT: HS-GAG biosynthesis",1,1]
["REACT:489","REACT: HS-GAG degradation",1,1]
["REACT:493","REACT: Heparan sulfate/heparin (HS-GAG) metabolism",1,1]
["REACT:494","REACT: Hexose transport",1,1]
["REACT:501","REACT: Homologous Recombination Repair",1,1]
["REACT:502","REACT: Homologous recombination repair of replication-independent double-strand breaks",1,1]
["REACT:524","REACT: Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell",1,1]
["REACT:526","REACT: Inactivation of APC/C via direct inhibition of the APC/C complex",1,1]
["REACT:528","REACT: Incretin Synthesis, Secretion, and Inactivation",1,1]
["REACT:529","REACT: Inflammasomes",1,1]
["REACT:534","REACT: Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits",1,1]
["REACT:538","REACT: Inhibition of Insulin Secretion by Adrenaline/Noradrenaline",1,1]
["REACT:544","REACT: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components",1,1]
["REACT:545","REACT: Initial triggering of complement",1,1]
["REACT:548","REACT: Insulin Synthesis and Processing",1,1]
["REACT:550","REACT: Insulin receptor recycling",1,1]
["REACT:555","REACT: Integrin alphaIIb beta3 signaling",1,1]
["REACT:556","REACT: Integrin cell surface interactions",1,1]
["REACT:557","REACT: Interaction between L1 and Ankyrins",1,1]
["REACT:558","REACT: Interactions of Rev with host cellular proteins",1,1]
["REACT:560","REACT: Interactions of Vpr with host cellular proteins",1,1]
["REACT:564","REACT: Interferon alpha/beta signaling",1,1]
["REACT:573","REACT: Intrinsic Pathway",1,1]
["REACT:575","REACT: Inwardly rectifying K+ channels",1,1]
["REACT:576","REACT: Ion channel transport",1,1]
["REACT:577","REACT: Ion transport by P-type ATPases",1,1]
["REACT:581","REACT: Keratan sulfate biosynthesis",1,1]
["REACT:583","REACT: Keratan sulfate/keratin metabolism",1,1]
["REACT:585","REACT: Kinesins",1,1]
["REACT:590","REACT: Lagging Strand Synthesis",1,1]
["REACT:592","REACT: Latent infection of Homo sapiens with Mycobacterium tuberculosis",1,1]
["REACT:596","REACT: Ligand-gated ion channel transport",1,1]
["REACT:604","REACT: Lysosome Vesicle Biogenesis",1,1]
["REACT:606","REACT: M Phase",1,1]
["REACT:611","REACT: MHC class II antigen presentation",1,1]
["REACT:615","REACT: Meiotic Synapsis",1,1]
["REACT:621","REACT: Metabolism of carbohydrates",1,1]
["REACT:625","REACT: Metabolism of nitric oxide",1,1]
["REACT:626","REACT: Metabolism of non-coding RNA",1,1]
["REACT:627","REACT: Metabolism of nucleotides",1,1]
["REACT:628","REACT: Metabolism of polyamines",1,1]
["REACT:632","REACT: Metabolism of steroid hormones and vitamins A and D",1,1]
["REACT:633","REACT: Metabolism of vitamins and cofactors",1,1]
["REACT:634","REACT: Metabolism of water-soluble vitamins and cofactors",1,1]
["REACT:635","REACT: Metal ion SLC transporters",1,1]
["REACT:638","REACT: MicroRNA (miRNA) Biogenesis",1,1]
["REACT:647","REACT: Mitochondrial tRNA aminoacylation",1,1]
["REACT:654","REACT: Mitotic Prometaphase",1,1]
["REACT:656","REACT: Mitotic Spindle Checkpoint",1,1]
["REACT:663","REACT: Muscle contraction",1,1]
["REACT:669","REACT: N-Glycan antennae elongation",1,1]
["REACT:670","REACT: N-glycan antennae elongation in the medial/trans-Golgi",1,1]
["REACT:676","REACT: NCAM1 interactions",1,1]
["REACT:677","REACT: NEP/NS2 Interacts with the Cellular Export Machinery",1,1]
["REACT:693","REACT: Na+/Cl- dependent neurotransmitter transporters",1,1]
["REACT:700","REACT: Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters",1,1]
["REACT:703","REACT: Negative regulators of RIG-I/MDA5 signaling",1,1]
["REACT:706","REACT: Netrin-1 signaling",1,1]
["REACT:716","REACT: Nitric oxide stimulates guanylate cyclase",1,1]
["REACT:726","REACT: Nuclear import of Rev protein",1,1]
["REACT:727","REACT: Nuclear signaling by ERBB4",1,1]
["REACT:728","REACT: Nucleosome assembly",1,1]
["REACT:731","REACT: Nucleotide-like (purinergic) receptors",1,1]
["REACT:732","REACT: O-linked glycosylation of mucins",1,1]
["REACT:734","REACT: Olfactory Signaling Pathway",1,1]
["REACT:744","REACT: Other semaphorin interactions",1,1]
["REACT:748","REACT: PD-1 signaling",1,1]
["REACT:751","REACT: PERK regulated gene expression",1,1]
["REACT:754","REACT: PI-3K cascade",1,1]
["REACT:756","REACT: PI3K events in ERBB2 signaling",1,1]
["REACT:757","REACT: PI3K events in ERBB4 signaling",1,1]
["REACT:759","REACT: PIP3 activates AKT signaling",1,1]
["REACT:760","REACT: PKA activation",1,1]
["REACT:761","REACT: PKA activation in glucagon signalling",1,1]
["REACT:762","REACT: PKA-mediated phosphorylation of CREB",1,1]
["REACT:766","REACT: PLC-gamma1 signalling",1,1]
["REACT:768","REACT: PLCG1 events in ERBB2 signaling",1,1]
["REACT:771","REACT: PTM: gamma carboxylation, hypusine formation and arylsulfatase activation",1,1]
["REACT:772","REACT: Packaging Of Telomere Ends",1,1]
["REACT:775","REACT: Pausing and recovery of HIV-1 elongation",1,1]
["REACT:776","REACT: Pausing and recovery of Tat-mediated HIV-1 elongation",1,1]
["REACT:781","REACT: Peroxisomal lipid metabolism",1,1]
["REACT:782","REACT: Phagosomal maturation (early endosomal stage)",1,1]
["REACT:784","REACT: Phase II conjugation",1,1]
["REACT:786","REACT: Phospholipase C-mediated cascade",1,1]
["REACT:788","REACT: Phosphorylation of CD3 and TCR zeta chains",1,1]
["REACT:792","REACT: Phosphorylation of the APC/C",1,1]
["REACT:795","REACT: Platelet Aggregation (Plug Formation)",1,1]
["REACT:797","REACT: Platelet calcium homeostasis",1,1]
["REACT:799","REACT: Platelet homeostasis",1,1]
["REACT:800","REACT: Platelet sensitization by LDL",1,1]
["REACT:807","REACT: Post-Elongation Processing of Intron-Containing pre-mRNA",1,1]
["REACT:808","REACT: Post-Elongation Processing of Intronless pre-mRNA",1,1]
["REACT:809","REACT: Post-Elongation Processing of the Transcript",1,1]
["REACT:810","REACT: Post-chaperonin tubulin folding pathway",1,1]
["REACT:812","REACT: Post-translational modification: synthesis of GPI-anchored proteins",1,1]
["REACT:813","REACT: Post-translational protein modification",1,1]
["REACT:818","REACT: Pre-NOTCH Processing in Golgi",1,1]
["REACT:821","REACT: Prefoldin mediated transfer of substrate  to CCT/TriC",1,1]
["REACT:826","REACT: Processing of Capped Intron-Containing Pre-mRNA",1,1]
["REACT:827","REACT: Processing of Capped Intronless Pre-mRNA",1,1]
["REACT:832","REACT: Processive synthesis on the lagging strand",1,1]
["REACT:834","REACT: Prolactin receptor signaling",1,1]
["REACT:838","REACT: Prostacyclin signalling through prostacyclin receptor",1,1]
["REACT:840","REACT: Protein folding",1,1]
["REACT:841","REACT: Proteolytic cleavage of SNARE complex proteins",1,1]
["REACT:846","REACT: Purine metabolism",1,1]
["REACT:851","REACT: Pyrimidine metabolism",1,1]
["REACT:854","REACT: Pyruvate metabolism",1,1]
["REACT:855","REACT: Pyruvate metabolism and Citric Acid (TCA) cycle",1,1]
["REACT:861","REACT: RNA Pol II CTD phosphorylation and interaction with CE",1,1]
["REACT:862","REACT: RNA Polymerase I Chain Elongation",1,1]
["REACT:864","REACT: RNA Polymerase I Promoter Escape",1,1]
["REACT:868","REACT: RNA Polymerase I Transcription Termination",1,1]
["REACT:874","REACT: RNA Polymerase II Transcription Elongation",1,1]
["REACT:878","REACT: RNA Polymerase II Transcription Termination",1,1]
["REACT:880","REACT: RNA Polymerase III Chain Elongation",1,1]
["REACT:886","REACT: RNA Polymerase III Transcription Termination",1,1]
["REACT:889","REACT: Rap1 signalling",1,1]
["REACT:901","REACT: Recycling pathway of L1",1,1]
["REACT:911","REACT: Regulation of Glucokinase by Glucokinase Regulatory Protein",1,1]
["REACT:913","REACT: Regulation of IFNA signaling",1,1]
["REACT:919","REACT: Regulation of Insulin Secretion by Glucagon-like Peptide-1",1,1]
["REACT:920","REACT: Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)",1,1]
["REACT:921","REACT: Regulation of KIT signaling",1,1]
["REACT:926","REACT: Regulation of Water Balance by Renal Aquaporins",1,1]
["REACT:928","REACT: Regulation of beta-cell development",1,1]
["REACT:931","REACT: Regulation of gene expression in beta cells",1,1]
["REACT:942","REACT: Regulatory RNA pathways",1,1]
["REACT:947","REACT: Removal of DNA patch containing abasic residue",1,1]
["REACT:952","REACT: Repair synthesis for gap-filling by DNA polymerase in TC-NER",1,1]
["REACT:953","REACT: Repair synthesis of patch ~27-30 bases long  by DNA polymerase",1,1]
["REACT:954","REACT: Resolution of AP sites via the multiple-nucleotide patch replacement pathway",1,1]
["REACT:956","REACT: Resolution of Abasic Sites (AP sites)",1,1]
["REACT:959","REACT: Respiratory electron transport",1,1]
["REACT:960","REACT: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.",1,1]
["REACT:961","REACT: Response of Mtb to phagocytosis",1,1]
["REACT:965","REACT: Rev-mediated nuclear export of HIV-1 RNA",1,1]
["REACT:971","REACT: Ribosomal scanning and start codon recognition",1,1]
["REACT:982","REACT: SHC-mediated cascade",1,1]
["REACT:990","REACT: SLC-mediated transmembrane transport",1,1]
["REACT:994","REACT: SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription",1,1]
["REACT:1008","REACT: Signal amplification",1,1]
["REACT:1019","REACT: Signaling by FGFR mutants",1,1]
["REACT:1021","REACT: Signaling by FGFR1 fusion mutants",1,1]
["REACT:1022","REACT: Signaling by FGFR1 mutants",1,1]
["REACT:1024","REACT: Signaling by FGFR2 mutants",1,1]
["REACT:1028","REACT: Signaling by Hippo",1,1]
["REACT:1031","REACT: Signaling by NODAL",1,1]
["REACT:1046","REACT: Signaling by constitutively active EGFR",1,1]
["REACT:1055","REACT: Smooth Muscle Contraction",1,1]
["REACT:1060","REACT: Sphingolipid de novo biosynthesis",1,1]
["REACT:1061","REACT: Sphingolipid metabolism",1,1]
["REACT:1065","REACT: Steroid hormones",1,1]
["REACT:1068","REACT: Striated Muscle Contraction",1,1]
["REACT:1072","REACT: Synthesis and interconversion of nucleotide di- and triphosphates",1,1]
["REACT:1078","REACT: Synthesis of PA",1,1]
["REACT:1084","REACT: Synthesis of PIPs at the Golgi membrane",1,1]
["REACT:1093","REACT: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol",1,1]
["REACT:1096","REACT: Synthesis of glycosylphosphatidylinositol (GPI)",1,1]
["REACT:1097","REACT: Synthesis of substrates in N-glycan biosythesis",1,1]
["REACT:1099","REACT: Synthesis, Secretion, and Deacylation of Ghrelin",1,1]
["REACT:1100","REACT: Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)",1,1]
["REACT:1104","REACT: TGF-beta receptor signaling activates SMADs",1,1]
["REACT:1109","REACT: TRAF6 mediated IRF7 activation",1,1]
["REACT:1125","REACT: Tat-mediated HIV-1 elongation arrest and recovery",1,1]
["REACT:1126","REACT: Tat-mediated elongation of the HIV-1 transcript",1,1]
["REACT:1127","REACT: Telomere C-strand (Lagging Strand) Synthesis",1,1]
["REACT:1130","REACT: Telomere Maintenance",1,1]
["REACT:1132","REACT: Termination of O-glycan biosynthesis",1,1]
["REACT:1139","REACT: The citric acid (TCA) cycle and respiratory electron transport",1,1]
["REACT:1142","REACT: The role of Nef in HIV-1 replication and disease pathogenesis",1,1]
["REACT:1144","REACT: Thromboxane signalling through TP receptor",1,1]
["REACT:1160","REACT: Trafficking of GluR2-containing AMPA receptors",1,1]
["REACT:1173","REACT: Translation initiation complex formation",1,1]
["REACT:1179","REACT: Translocation of ZAP-70 to Immunological synapse",1,1]
["REACT:1185","REACT: Transport of Mature Transcript to Cytoplasm",1,1]
["REACT:1186","REACT: Transport of Mature mRNA Derived from an Intronless Transcript",1,1]
["REACT:1187","REACT: Transport of Mature mRNA derived from an Intron-Containing Transcript",1,1]
["REACT:1188","REACT: Transport of Mature mRNAs Derived from Intronless Transcripts",1,1]
["REACT:1189","REACT: Transport of Ribonucleoproteins into the Host Nucleus",1,1]
["REACT:1194","REACT: Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds",1,1]
["REACT:1195","REACT: Transport of inorganic cations/anions and amino acids/oligopeptides",1,1]
["REACT:1199","REACT: Transport of the SLBP Dependant Mature mRNA",1,1]
["REACT:1200","REACT: Transport of the SLBP independent Mature mRNA",1,1]
["REACT:1201","REACT: Transport of vitamins, nucleosides, and related molecules",1,1]
["REACT:1202","REACT: Transport to the Golgi and subsequent modification",1,1]
["REACT:1203","REACT: Triglyceride Biosynthesis",1,1]
["REACT:1213","REACT: Unfolded Protein Response",1,1]
["REACT:1223","REACT: Viral Messenger RNA Synthesis",1,1]
["REACT:1239","REACT: Vpr-mediated nuclear import of PICs",1,1]
["REACT:1241","REACT: Xenobiotics",1,1]
["REACT:1245","REACT: Zinc transporters",1,1]
["REACT:1251","REACT: cGMP effects",1,1]
["REACT:1254","REACT: eNOS activation and regulation",1,1]
["REACT:1255","REACT: mRNA 3'-end processing",1,1]
["REACT:1256","REACT: mRNA Capping",1,1]
["REACT:1258","REACT: mRNA Decay by 5' to 3' Exoribonuclease",1,1]
["REACT:1262","REACT: mRNA Processing",1,1]
["REACT:1263","REACT: mRNA Splicing",1,1]
["REACT:1264","REACT: mRNA Splicing - Major Pathway",1,1]
["REACT:1265","REACT: mRNA Splicing - Minor Pathway",1,1]
["REACT:1270","REACT: p130Cas linkage to MAPK signaling for integrins",1,1]
["REACT:1280","REACT: p75NTR signals via NF-kB",1,1]
["REACT:1282","REACT: snRNP Assembly",1,1]
["REACT:1284","REACT: tRNA Aminoacylation",1,1]
["KEGG:00010","Glycolysis / Gluconeogenesis",1,1]
["KEGG:00020","Citrate cycle (TCA cycle)",1,1]
["KEGG:00030","Pentose phosphate pathway",1,1]
["KEGG:00040","Pentose and glucuronate interconversions",1,1]
["KEGG:00051","Fructose and mannose metabolism",1,1]
["KEGG:00052","Galactose metabolism",1,1]
["KEGG:00053","Ascorbate and aldarate metabolism",1,1]
["KEGG:00062","Fatty acid elongation",1,1]
["KEGG:00071","Fatty acid metabolism",1,1]
["KEGG:00100","Steroid biosynthesis",1,1]
["KEGG:00190","Oxidative phosphorylation",1,1]
["KEGG:00230","Purine metabolism",1,1]
["KEGG:00240","Pyrimidine metabolism",1,1]
["KEGG:00250","Alanine, aspartate and glutamate metabolism",1,1]
["KEGG:00330","Arginine and proline metabolism",1,1]
["KEGG:00340","Histidine metabolism",1,1]
["KEGG:00350","Tyrosine metabolism",1,1]
["KEGG:00360","Phenylalanine metabolism",1,1]
["KEGG:00380","Tryptophan metabolism",1,1]
["KEGG:00410","beta-Alanine metabolism",1,1]
["KEGG:00450","Selenocompound metabolism",1,1]
["KEGG:00480","Glutathione metabolism",1,1]
["KEGG:00500","Starch and sucrose metabolism",1,1]
["KEGG:00510","N-Glycan biosynthesis",1,1]
["KEGG:00511","Other glycan degradation",1,1]
["KEGG:00512","Mucin type O-Glycan biosynthesis",1,1]
["KEGG:00514","Other types of O-glycan biosynthesis",1,1]
["KEGG:00520","Amino sugar and nucleotide sugar metabolism",1,1]
["KEGG:00531","Glycosaminoglycan degradation",1,1]
["KEGG:00532","Glycosaminoglycan biosynthesis - chondroitin sulfate",1,1]
["KEGG:00533","Glycosaminoglycan biosynthesis - keratan sulfate",1,1]
["KEGG:00534","Glycosaminoglycan biosynthesis - heparan sulfate",1,1]
["KEGG:00561","Glycerolipid metabolism",1,1]
["KEGG:00563","Glycosylphosphatidylinositol(GPI)-anchor biosynthesis",1,1]
["KEGG:00565","Ether lipid metabolism",1,1]
["KEGG:00590","Arachidonic acid metabolism",1,1]
["KEGG:00591","Linoleic acid metabolism",1,1]
["KEGG:00592","alpha-Linolenic acid metabolism",1,1]
["KEGG:00600","Sphingolipid metabolism",1,1]
["KEGG:00601","Glycosphingolipid biosynthesis - lacto and neolacto series",1,1]
["KEGG:00604","Glycosphingolipid biosynthesis - ganglio series",1,1]
["KEGG:00620","Pyruvate metabolism",1,1]
["KEGG:00630","Glyoxylate and dicarboxylate metabolism",1,1]
["KEGG:00640","Propanoate metabolism",1,1]
["KEGG:00650","Butanoate metabolism",1,1]
["KEGG:00670","One carbon pool by folate",1,1]
["KEGG:00760","Nicotinate and nicotinamide metabolism",1,1]
["KEGG:00770","Pantothenate and CoA biosynthesis",1,1]
["KEGG:00830","Retinol metabolism",1,1]
["KEGG:00860","Porphyrin and chlorophyll metabolism",1,1]
["KEGG:00900","Terpenoid backbone biosynthesis",1,1]
["KEGG:00970","Aminoacyl-tRNA biosynthesis",1,1]
["KEGG:00980","Metabolism of xenobiotics by cytochrome P450",1,1]
["KEGG:00982","Drug metabolism - cytochrome P450",1,1]
["KEGG:00983","Drug metabolism - other enzymes",1,1]
["KEGG:01040","Biosynthesis of unsaturated fatty acids",1,1]
["KEGG:03008","Ribosome biogenesis in eukaryotes",1,1]
["KEGG:03018","RNA degradation",1,1]
["KEGG:03020","RNA polymerase",1,1]
["KEGG:03030","DNA replication",1,1]
["KEGG:03040","Spliceosome",1,1]
["KEGG:03060","Protein export",1,1]
["KEGG:03410","Base excision repair",1,1]
["KEGG:03430","Mismatch repair",1,1]
["KEGG:03440","Homologous recombination",1,1]
["KEGG:03460","Fanconi anemia pathway",1,1]
["KEGG:04060","Cytokine-cytokine receptor interaction",1,1]
["KEGG:04130","SNARE interactions in vesicular transport",1,1]
["KEGG:04140","Regulation of autophagy",1,1]
["KEGG:04142","Lysosome",1,1]
["KEGG:04260","Cardiac muscle contraction",1,1]
["KEGG:04512","ECM-receptor interaction",1,1]
["KEGG:04610","Complement and coagulation cascades",1,1]
["KEGG:04612","Antigen processing and presentation",1,1]
["KEGG:04614","Renin-angiotensin system",1,1]
["KEGG:04640","Hematopoietic cell lineage",1,1]
["KEGG:04672","Intestinal immune network for IgA production",1,1]
["KEGG:04744","Phototransduction",1,1]
["KEGG:04940","Type I diabetes mellitus",1,1]
["KEGG:04950","Maturity onset diabetes of the young",1,1]
["KEGG:04964","Proximal tubule bicarbonate reclamation",1,1]
["KEGG:04966","Collecting duct acid secretion",1,1]
["KEGG:04974","Protein digestion and absorption",1,1]
["KEGG:04976","Bile secretion",1,1]
["KEGG:04977","Vitamin digestion and absorption",1,1]
["KEGG:04978","Mineral absorption",1,1]
["KEGG:05030","Cocaine addiction",1,1]
["KEGG:05110","Vibrio cholerae infection",1,1]
["KEGG:05134","Legionellosis",1,1]
["KEGG:05144","Malaria",1,1]
["KEGG:05150","Staphylococcus aureus infection",1,1]
["KEGG:05217","Basal cell carcinoma",1,1]
["KEGG:05310","Asthma",1,1]
["KEGG:05320","Autoimmune thyroid disease",1,1]
["KEGG:05322","Systemic lupus erythematosus",1,1]
["KEGG:05323","Rheumatoid arthritis",1,1]
["KEGG:05330","Allograft rejection",1,1]
["KEGG:05332","Graft-versus-host disease",1,1]
["KEGG:05412","Arrhythmogenic right ventricular cardiomyopathy (ARVC)",1,1]
["KEGG:05414","Dilated cardiomyopathy",1,1]
["NCI:2","NCI:A6B1_A6B4_INTEGRIN_PATHWAY",1,1]
["NCI:8","NCI:AMB2_NEUTROPHILS_PATHWAY",1,1]
["NCI:12","NCI:ARF_3PATHWAY",1,1]
["NCI:14","NCI:ARF6_PATHWAY",1,1]
["NCI:15","NCI:ARF6_TRAFFICKINGPATHWAY",1,1]
["NCI:22","NCI:AURORA_A_PATHWAY",1,1]
["NCI:31","NCI:BETACATENIN_NUC_PATHWAY",1,1]
["NCI:41","NCI:CIRCADIANPATHWAY",1,1]
["NCI:43","NCI:CONE_PATHWAY",1,1]
["NCI:46","NCI:DELTANP63PATHWAY",1,1]
["NCI:47","NCI:DNAPK_PATHWAY",1,1]
["NCI:50","NCI:ECADHERIN_KERATINOCYTE_PATHWAY",1,1]
["NCI:51","NCI:ECADHERIN_NASCENTAJ_PATHWAY",1,1]
["NCI:52","NCI:ECADHERIN_STABILIZATION_PATHWAY",1,1]
["NCI:54","NCI:EPHA2_FWDPATHWAY",1,1]
["NCI:73","NCI:FANCONI_PATHWAY",1,1]
["NCI:79","NCI:FRA_PATHWAY",1,1]
["NCI:80","NCI:GLYPICAN_1PATHWAY",1,1]
["NCI:86","NCI:HDAC_CLASSII_PATHWAY",1,1]
["NCI:88","NCI:HEDGEHOG_2PATHWAY",1,1]
["NCI:90","NCI:HES_HEYPATHWAY",1,1]
["NCI:95","NCI:HNF3APATHWAY",1,1]
["NCI:96","NCI:HNF3BPATHWAY",1,1]
["NCI:104","NCI:IL23PATHWAY",1,1]
["NCI:105","NCI:IL27PATHWAY",1,1]
["NCI:106","NCI:IL2_PI3KPATHWAY",1,1]
["NCI:107","NCI:IL2_STAT5PATHWAY",1,1]
["NCI:108","NCI:IL3_PATHWAY",1,1]
["NCI:115","NCI:ILK_PATHWAY",1,1]
["NCI:116","NCI:INSULIN_GLUCOSE_PATHWAY",1,1]
["NCI:117","NCI:INSULIN_PATHWAY",1,1]
["NCI:118","NCI:INTEGRIN1_PATHWAY",1,1]
["NCI:119","NCI:INTEGRIN2_PATHWAY",1,1]
["NCI:120","NCI:INTEGRIN3_PATHWAY",1,1]
["NCI:122","NCI:INTEGRIN5_PATHWAY",1,1]
["NCI:124","NCI:INTEGRIN_A4B1_PATHWAY",1,1]
["NCI:125","NCI:INTEGRIN_A9B1_PATHWAY",1,1]
["NCI:126","NCI:INTEGRIN_CS_PATHWAY",1,1]
["NCI:129","NCI:LKB1_PATHWAY",1,1]
["NCI:130","NCI:LPA4_PATHWAY",1,1]
["NCI:140","NCI:NECTIN_PATHWAY",1,1]
["NCI:146","NCI:NFKAPPABATYPICALPATHWAY",1,1]
["NCI:148","NCI:NOTCH_PATHWAY",1,1]
["NCI:162","NCI:PI3KCIAKTPATHWAY",1,1]
["NCI:165","NCI:PI3KPLCTRKPATHWAY",1,1]
["NCI:166","NCI:PLEXIND1_PATHWAY",1,1]
["NCI:167","NCI:PLK1_PATHWAY",1,1]
["NCI:173","NCI:PTP1BPATHWAY",1,1]
["NCI:186","NCI:RHODOPSIN_PATHWAY",1,1]
["NCI:188","NCI:S1P_META_PATHWAY",1,1]
["NCI:194","NCI:SHP2_PATHWAY",1,1]
["NCI:199","NCI:SYNDECAN_3_PATHWAY",1,1]
["NCI:200","NCI:SYNDECAN_4_PATHWAY",1,1]
["NCI:209","NCI:TGFBRPATHWAY",1,1]
["NCI:211","NCI:THROMBIN_PAR4_PATHWAY",1,1]
["NCI:218","NCI:UPA_UPAR_PATHWAY",1,1]
["NCI:222","NCI:WNT_CANONICAL_PATHWAY",1,1]
["NCI:224","NCI:WNT_SIGNALING_PATHWAY",1,1]

{"sheet":"Table S14E. BrainDevExpr. Enr","index":5,"n_rows":16,"n_cols":6,"rows_kept":16,"cut":false,"hidden":false,"merged":[]}
["Contingency Table"]
["Functional groups","prenatally","postnatally","unbiased","others","(total)"]
["synaptic signalling+satellite synaptic",4,13,16,0,33]
["MAPK & other signalling",5,6,10,1,22]
["chromatin remodeling & transcription regulation",22,7,17,2,48]
["others",1,3,6,0,10]
["(total)",32,29,49,3,113]
[]
[]
[]
["One-tail Fisher exact test (enrichment), P value"]
["Functional groups","prenatally","postnatally","unbiased","others"]
["synaptic signalling+satellite synaptic",0.99769943077776602,3.00755626216338E-2,0.3087874528054817,"NA"]
["MAPK & other signalling",0.81790175878020488,0.52051894837029411,0.50495103781238648,0.48113489595790504]
["chromatin remodeling & transcription regulation",4.1559044466066286E-4,0.99525510580106902,0.95168717151298987,0.38702292684593553]
["others",0.96974656498661371,0.49851279242282942,0.21763778041388493,"NS"]