%0 Journal Article %T Trans-cranial focused ultrasound without hair shaving: feasibility study in an ex vivo cadaver model %+ Extramural Research %+ Department of Radiation Oncology %+ Department of Neurosurgery %+ Physique des ondes pour la médecine %A Eames, Matthew %A Hananel, Arik %A Snell, John %A Kassell, Neal %A Aubry, Jean-Francois %< avec comité de lecture %J Journal of Therapeutic Ultrasound %I BioMed Central %V 1 %N 1 %P 24 %8 2013 %D 2013 %K tcMRgFUS %K Brain %K Hair %K MR thermometry %Z Life Sciences [q-bio]/Bioengineering/Nuclear medicineJournal articles %X In preparing a patient for a trans-cranial magnetic resonance (MR)-guided focused ultrasound procedure, current practice is to shave the patient's head on treatment day. Here we present an initial attempt to evaluate the feasibility of trans-cranial focused ultrasound in an unshaved, ex vivo human head model. A human skull filled with tissue-mimicking phantom and covered with a wig made of human hair was sonicated using 220- and 710-kHz head transducers to evaluate the feasibility of acoustic energy transfer. Heating at the focal point was measured by MR proton resonance shift thermometry. Results showed that the hair had a negligible effect on focal spot thermal rise at 220 kHz and a 17% drop in temperature elevation when using 710 kHz. %G English %2 https://inserm.hal.science/inserm-00923402/document %2 https://inserm.hal.science/inserm-00923402/file/2050-5736-1-24.pdf %L inserm-00923402 %U https://inserm.hal.science/inserm-00923402 %~ INSERM %~ ESPCI %~ CNRS %~ PARISTECH %~ PSL %~ UP-SCIENCES %~ ESPCI-PSL