Dengue epidemics and adverse obstetrical outcomes in French Guiana: a semi-ecological study. - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Tropical Medicine and International Health Year : 2014

Dengue epidemics and adverse obstetrical outcomes in French Guiana: a semi-ecological study.

Abstract

OBJECTIVE: To determine whether dengue epidemics are associated with an increase in adverse obstetrical outcomes. METHODS: Semi-ecological study combining individual data on obstetrical events from the perinatal registry and aggregated exposure data from the epidemiologic surveillance of dengue in Cayenne, French Guiana between 2004 and 2007. RESULTS: After adjustment for individual risk factors, analysis showed that an epidemic level of dengue transmission during the first trimester was associated with an increased risk of post-partum haemorrhage and preterm birth. The associated risks seemed to depend on the epidemic level. CONCLUSIONS: Despite its limitations, this study suggests that dengue in the first trimester may be related to preterm birth and to post-partum bleeding, thus leading to specific hypotheses that should be tested in prospective studies.
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Dates and versions

inserm-00922102 , version 1 (23-12-2013)

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Matthieu Hanf, Eleanor Friedman, Celia Basurko, Amaury Roger, Pascal Bruncher, et al.. Dengue epidemics and adverse obstetrical outcomes in French Guiana: a semi-ecological study.: Dengue and adverse obstetrical outcomes. Tropical Medicine and International Health, 2014, 19 (2), pp.153-8. ⟨10.1111/tmi.12240⟩. ⟨inserm-00922102⟩
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