<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of inserm-00827220</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-24T06:36:36+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Role of warm ischemia on innate and adaptive responses in a preclinical renal auto-transplanted porcine model.</title>
            <author role="aut">
              <persName>
                <forename type="first">Ludivine</forename>
                <surname>Rossard</surname>
              </persName>
              <email type="md5">a520988eb6d13333def8bfd12242825d</email>
              <email type="domain">hotmail.com</email>
              <idno type="idhal" notation="numeric">941871</idno>
              <idno type="halauthorid" notation="string">713134-941871</idno>
              <affiliation ref="#struct-182187"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Frédéric</forename>
                <surname>Favreau</surname>
              </persName>
              <email type="md5">6dfd59e684c2e71f54c252785e4d6c05</email>
              <email type="domain">gmail.com</email>
              <idno type="idhal" notation="numeric">1079298</idno>
              <idno type="halauthorid" notation="string">413447-1079298</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-3754-0070</idno>
              <idno type="IDREF">https://www.idref.fr/069163855</idno>
              <idno type="VIAF">https://viaf.org/viaf/172552048</idno>
              <idno type="ISNI">http://isni.org/isni/0000000122677432</idno>
              <affiliation ref="#struct-182187"/>
              <affiliation ref="#struct-467918"/>
              <affiliation ref="#struct-108271"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Sebastien</forename>
                <surname>Giraud</surname>
              </persName>
              <email type="md5">63e5426ef858069571b1717783999f39</email>
              <email type="domain">univ-poitiers.fr</email>
              <idno type="idhal" notation="string">sebastien-giraud</idno>
              <idno type="idhal" notation="numeric">941873</idno>
              <idno type="halauthorid" notation="string">713135-941873</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-9015-8968</idno>
              <idno type="IDREF">https://www.idref.fr/185264085</idno>
              <idno type="VIAF">https://viaf.org/viaf/315737234</idno>
              <affiliation ref="#struct-182187"/>
              <affiliation ref="#struct-467918"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Raphael</forename>
                <surname>Thuillier</surname>
              </persName>
              <email type="md5">e4e64c9f897da12ab883a3a1d1a50042</email>
              <email type="domain">gmail.com</email>
              <idno type="idhal" notation="string">raphael-thuillier</idno>
              <idno type="idhal" notation="numeric">10250</idno>
              <idno type="halauthorid" notation="string">16897-10250</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/P-5709-2016</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-7482-0031</idno>
              <idno type="IDREF">https://www.idref.fr/174952384</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/P-5709-2016</idno>
              <idno type="VIAF">https://viaf.org/viaf/2148874543249622387</idno>
              <affiliation ref="#struct-182187"/>
              <affiliation ref="#struct-467918"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Sylvain</forename>
                <surname>Le Pape</surname>
              </persName>
              <email type="md5">792b77fa058e0614487e22c78a47de91</email>
              <email type="domain">univ-poitiers.fr</email>
              <idno type="idhal" notation="numeric">941874</idno>
              <idno type="halauthorid" notation="string">713136-941874</idno>
              <idno type="IDREF">https://www.idref.fr/243494211</idno>
              <idno type="VIAF">https://viaf.org/viaf/1602159233959203370213</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-7439-7184</idno>
              <affiliation ref="#struct-182187"/>
              <affiliation ref="#struct-108271"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean</forename>
                <forename type="middle">Michel</forename>
                <surname>Goujon</surname>
              </persName>
              <email type="md5">2d110edb40c9f47491f2ddb20e6434f8</email>
              <email type="domain">chu-poitiers.fr</email>
              <idno type="idhal" notation="numeric">920028</idno>
              <idno type="halauthorid" notation="string">713137-920028</idno>
              <idno type="IDREF">https://www.idref.fr/060946911</idno>
              <idno type="VIAF">https://viaf.org/viaf/216064008</idno>
              <affiliation ref="#struct-182187"/>
              <affiliation ref="#struct-467918"/>
              <affiliation ref="#struct-108271"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Alexandre</forename>
                <surname>Valagier</surname>
              </persName>
              <email type="md5">e7b66a6e8e9bddb9b7665e2ec101e49e</email>
              <email type="domain">chu-poitiers.fr</email>
              <idno type="idhal" notation="numeric">941876</idno>
              <idno type="halauthorid" notation="string">683842-941876</idno>
              <affiliation ref="#struct-182187"/>
            </author>
            <author role="crp">
              <persName>
                <forename type="first">Thierry</forename>
                <surname>Hauet</surname>
              </persName>
              <email type="md5">3d17ae582827ce0561e5ae4dd40734bb</email>
              <email type="domain">univ-poitiers.fr</email>
              <idno type="idhal" notation="numeric">989898</idno>
              <idno type="halauthorid" notation="string">612031-989898</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-0117-071X</idno>
              <idno type="IDREF">https://www.idref.fr/070316767</idno>
              <idno type="VIAF">https://viaf.org/viaf/172823895</idno>
              <affiliation ref="#struct-182187"/>
              <affiliation ref="#struct-467918"/>
              <affiliation ref="#struct-108271"/>
              <affiliation ref="#struct-132921"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Ed.</forename>
                <surname>BMC</surname>
              </persName>
              <email type="md5">7bc004cf734e1645c1468c005ceafbd9</email>
              <email type="domain">biomedcentral.com.invalid</email>
            </editor>
            <funder>This work was supported by grants from the Ministère Français de l'Enseignement Supérieur et de la Recherche, Conseil Régional Poitou-Charentes, University of Poitiers, Banque Tarneaud, University Hospital of Poitiers, Institut National de Recherche Agronomique and French Society of Organ Transplantation</funder>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2013-05-29 09:06:03</date>
              <date type="whenModified">2026-03-31 08:16:03</date>
              <date type="whenReleased">2013-05-29 12:35:41</date>
              <date type="whenProduced">2013-05-24</date>
              <date type="whenEndEmbargoed">2013-05-29</date>
              <ref type="file" target="https://inserm.hal.science/inserm-00827220v1/document">
                <date notBefore="2013-05-29"/>
              </ref>
              <ref type="file" subtype="greenPublisher" n="1" target="https://inserm.hal.science/inserm-00827220v1/file/1479-5876-11-129.pdf" id="file-827220-315843">
                <date notBefore="2013-05-29"/>
              </ref>
              <ref type="annex" subtype="other" n="0" target="https://inserm.hal.science/inserm-00827220v1/file/1479-5876-11-129-S1.PPT" id="file-827220-315842">
                <date notBefore="2013-05-29"/>
              </ref>
              <ref type="annex" subtype="other" n="0" target="https://inserm.hal.science/inserm-00827220v1/file/1479-5876-11-129.xml" id="file-827220-315841">
                <date notBefore="2013-05-29"/>
              </ref>
              <ref type="externalLink" target="https://translational-medicine.biomedcentral.com/track/pdf/10.1186/1479-5876-11-129"/>
              <fs>
                <f name="inra_etatDocument_local" notation="string" n="VE">
                  <string>inra_etatDocument_local_VE</string>
                </f>
                <f name="inra_publicVise_local" notation="string" n="SC">
                  <string>inra_publicVise_local_SC</string>
                </f>
              </fs>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="151596">
                <persName>
                  <forename>Ed.</forename>
                  <surname>BMC</surname>
                </persName>
                <email type="md5">7bc004cf734e1645c1468c005ceafbd9</email>
                <email type="domain">biomedcentral.com.invalid</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">inserm-00827220</idno>
            <idno type="halUri">https://inserm.hal.science/inserm-00827220</idno>
            <idno type="halBibtex">rossard:inserm-00827220</idno>
            <idno type="halRefHtml">&lt;i&gt;Journal of Translational Medicine&lt;/i&gt;, 2013, 11 (1), pp.129. &lt;a target="_blank" href="https://dx.doi.org/10.1186/1479-5876-11-129"&gt;&amp;#x27E8;10.1186/1479-5876-11-129&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Journal of Translational Medicine, 2013, 11 (1), pp.129. &amp;#x27E8;10.1186/1479-5876-11-129&amp;#x27E9;</idno>
            <availability status="restricted">
              <licence target="https://creativecommons.org/licenses/by/4.0/">CC BY 4.0 - Attribution<ref corresp="#file-827220-315843"/><ref corresp="#file-827220-315842"/><ref corresp="#file-827220-315841"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="INSERM">INSERM - Institut national de la santé et de la recherche médicale</idno>
            <idno type="stamp" n="UNIV-POITIERS">Université de Poitiers</idno>
            <idno type="stamp" n="INRA">INRA - Institut national de la recherche agronomique</idno>
            <idno type="stamp" n="AGREENIUM">Archive ouverte en agrobiosciences</idno>
            <idno type="stamp" n="IRTOMIT">Ischémie Reperfusion en Transplantation d’Organes Mécanismes et Innovations Thérapeutiques</idno>
            <idno type="stamp" n="INRAE">Institut National de Recherche en Agriculture, Alimentation et Environnement</idno>
            <idno type="stamp" n="IRMETIST">Ischémie Reperfusion, Métabolisme et Inflammation Stérile en Transplantation</idno>
            <idno type="stamp" n="CHU-POITIERS">CHU-POITIERS</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Role of warm ischemia on innate and adaptive responses in a preclinical renal auto-transplanted porcine model.</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Ludivine</forename>
                    <surname>Rossard</surname>
                  </persName>
                  <email type="md5">a520988eb6d13333def8bfd12242825d</email>
                  <email type="domain">hotmail.com</email>
                  <idno type="idhal" notation="numeric">941871</idno>
                  <idno type="halauthorid" notation="string">713134-941871</idno>
                  <affiliation ref="#struct-182187"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Frédéric</forename>
                    <surname>Favreau</surname>
                  </persName>
                  <email type="md5">6dfd59e684c2e71f54c252785e4d6c05</email>
                  <email type="domain">gmail.com</email>
                  <idno type="idhal" notation="numeric">1079298</idno>
                  <idno type="halauthorid" notation="string">413447-1079298</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-3754-0070</idno>
                  <idno type="IDREF">https://www.idref.fr/069163855</idno>
                  <idno type="VIAF">https://viaf.org/viaf/172552048</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000122677432</idno>
                  <affiliation ref="#struct-182187"/>
                  <affiliation ref="#struct-467918"/>
                  <affiliation ref="#struct-108271"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Sebastien</forename>
                    <surname>Giraud</surname>
                  </persName>
                  <email type="md5">63e5426ef858069571b1717783999f39</email>
                  <email type="domain">univ-poitiers.fr</email>
                  <idno type="idhal" notation="string">sebastien-giraud</idno>
                  <idno type="idhal" notation="numeric">941873</idno>
                  <idno type="halauthorid" notation="string">713135-941873</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-9015-8968</idno>
                  <idno type="IDREF">https://www.idref.fr/185264085</idno>
                  <idno type="VIAF">https://viaf.org/viaf/315737234</idno>
                  <affiliation ref="#struct-182187"/>
                  <affiliation ref="#struct-467918"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Raphael</forename>
                    <surname>Thuillier</surname>
                  </persName>
                  <email type="md5">e4e64c9f897da12ab883a3a1d1a50042</email>
                  <email type="domain">gmail.com</email>
                  <idno type="idhal" notation="string">raphael-thuillier</idno>
                  <idno type="idhal" notation="numeric">10250</idno>
                  <idno type="halauthorid" notation="string">16897-10250</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/P-5709-2016</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-7482-0031</idno>
                  <idno type="IDREF">https://www.idref.fr/174952384</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/P-5709-2016</idno>
                  <idno type="VIAF">https://viaf.org/viaf/2148874543249622387</idno>
                  <affiliation ref="#struct-182187"/>
                  <affiliation ref="#struct-467918"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Sylvain</forename>
                    <surname>Le Pape</surname>
                  </persName>
                  <email type="md5">792b77fa058e0614487e22c78a47de91</email>
                  <email type="domain">univ-poitiers.fr</email>
                  <idno type="idhal" notation="numeric">941874</idno>
                  <idno type="halauthorid" notation="string">713136-941874</idno>
                  <idno type="IDREF">https://www.idref.fr/243494211</idno>
                  <idno type="VIAF">https://viaf.org/viaf/1602159233959203370213</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-7439-7184</idno>
                  <affiliation ref="#struct-182187"/>
                  <affiliation ref="#struct-108271"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean</forename>
                    <forename type="middle">Michel</forename>
                    <surname>Goujon</surname>
                  </persName>
                  <email type="md5">2d110edb40c9f47491f2ddb20e6434f8</email>
                  <email type="domain">chu-poitiers.fr</email>
                  <idno type="idhal" notation="numeric">920028</idno>
                  <idno type="halauthorid" notation="string">713137-920028</idno>
                  <idno type="IDREF">https://www.idref.fr/060946911</idno>
                  <idno type="VIAF">https://viaf.org/viaf/216064008</idno>
                  <affiliation ref="#struct-182187"/>
                  <affiliation ref="#struct-467918"/>
                  <affiliation ref="#struct-108271"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Alexandre</forename>
                    <surname>Valagier</surname>
                  </persName>
                  <email type="md5">e7b66a6e8e9bddb9b7665e2ec101e49e</email>
                  <email type="domain">chu-poitiers.fr</email>
                  <idno type="idhal" notation="numeric">941876</idno>
                  <idno type="halauthorid" notation="string">683842-941876</idno>
                  <affiliation ref="#struct-182187"/>
                </author>
                <author role="crp">
                  <persName>
                    <forename type="first">Thierry</forename>
                    <surname>Hauet</surname>
                  </persName>
                  <email type="md5">3d17ae582827ce0561e5ae4dd40734bb</email>
                  <email type="domain">univ-poitiers.fr</email>
                  <idno type="idhal" notation="numeric">989898</idno>
                  <idno type="halauthorid" notation="string">612031-989898</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-0117-071X</idno>
                  <idno type="IDREF">https://www.idref.fr/070316767</idno>
                  <idno type="VIAF">https://viaf.org/viaf/172823895</idno>
                  <affiliation ref="#struct-182187"/>
                  <affiliation ref="#struct-467918"/>
                  <affiliation ref="#struct-108271"/>
                  <affiliation ref="#struct-132921"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">1598</idno>
                <idno type="eissn">1479-5876</idno>
                <title level="j">Journal of Translational Medicine</title>
                <imprint>
                  <publisher>BioMed Central</publisher>
                  <biblScope unit="volume">11</biblScope>
                  <biblScope unit="issue">1</biblScope>
                  <biblScope unit="pp">129</biblScope>
                  <date type="datePub">2013-05-24</date>
                  <date type="dateEpub">2013-05-24</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1186/1479-5876-11-129</idno>
              <idno type="prodinra">208542</idno>
              <idno type="pubmed">23706041</idno>
              <idno type="wos">000319662800001</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="it">Ischemia-reperfusion</term>
                <term xml:lang="it">Adaptive immune response</term>
                <term xml:lang="it">Innate immune response</term>
                <term xml:lang="it">Kidney transplantation</term>
                <term xml:lang="it">Preclinical porcine model</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv.mhep">Life Sciences [q-bio]/Human health and pathology</classCode>
              <classCode scheme="halDomain" n="sdv.mhep.chi">Life Sciences [q-bio]/Human health and pathology/Surgery</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>BACKGROUND: Deceased after cardiac arrest donor are an additional source of kidney graft to overcome graft shortage. Deciphering the respective role of renal warm and cold ischemia is of pivotal interest in the transplantation process. METHODS: Using a preclinical pig model of renal auto-transplantation, we investigated the consequences of warm and cold ischemia on early innate and adaptive responses as well as graft outcome. Kidneys were subjected to either 60 min-warm ischemia (WI) or auto-transplanted after cold storage for 24 h at 4[degree sign]C (CS), or both conditions combined (WI + CS). Renal function, immune response and cytokine expression, oxidative stress and cell death were investigated at 3 h, 3 and 7 days (H3, D3 and D7) after reperfusion. At 3 months, we focused on cell infiltration and tissue remodelling. RESULTS: WI + CS induced a delayed graft function linked to higher tubular damage. Innate response occurred at D3 associated to a pro-oxidative milieu with a level dependent on the severity of ischemic injury whereas adaptive immune response occurred only at D7 mainly due to CS injuries and aggravated by WI. Graft cellular death was an early event detected at H3 and seems to be one of the first ischemia reperfusion injuries. These early injuries affect graft outcome on renal function, cells infiltration and fibrosis development. CONCLUSIONS: The results indicate that the severe ischemic insult found in kidneys from deceased after cardiac arrest donor affects kidney outcome and promotes an uncontrolled deleterious innate and adaptive response not inhibited 3 months after reperfusion.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-182187" status="OLD">
          <idno type="IdRef">168442019</idno>
          <idno type="RNSR">201220164V</idno>
          <idno type="Wikidata">Q51781141</idno>
          <orgName>Ischémie Reperfusion en Transplantation d’Organes Mécanismes et Innovations Thérapeutiques [U 1082]</orgName>
          <orgName type="acronym">IRTOMIT [Poitiers]</orgName>
          <date type="start">2012-01-01</date>
          <date type="end">2021-12-31</date>
          <desc>
            <address>
              <addrLine>Facultés de Médecine et Pharmacie  -  Campus CHU Poitiers -  CS 90577. 2 rue de la Milétrie. 86021 Poitiers Cedex</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation name="UMR-S 1082" active="#struct-54493" type="direct"/>
            <relation name="U1082" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-467918" status="VALID">
          <orgName>Service de Biochimie [CHU Poitiers]</orgName>
          <desc>
            <address>
              <addrLine>Pôle UBM, Poitiers, 86021</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-520300" type="direct"/>
            <relation active="#struct-300170" type="indirect"/>
          </listRelation>
        </org>
        <org type="regrouplaboratory" xml:id="struct-108271" status="VALID">
          <idno type="IdRef">034799990</idno>
          <idno type="ISNI">0000000121696383</idno>
          <orgName>Université de Poitiers – UFR Santé [Faculté de Médecine et de Pharmacie]</orgName>
          <orgName type="acronym">UFR Santé [Poitiers]</orgName>
          <date type="start">1968-10-01</date>
          <desc>
            <address>
              <addrLine>Bâtiment D1 – 6 rue de la Milétrie – TSA 51 115 – 86073 Poitiers Cedex 9 – France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://medphar.univ-poitiers.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-54493" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-132921" status="OLD">
          <orgName>Groupement Scientifique - Ibisa</orgName>
          <orgName type="acronym">IBISA</orgName>
          <date type="start">2008-01-01</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>INRA - Centre-Siège</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation name="UAR1311" active="#struct-92114" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-54493" status="VALID">
          <idno type="IdRef">026403765</idno>
          <idno type="ISNI">0000000121606368</idno>
          <idno type="ROR">https://ror.org/04xhy8q59</idno>
          <idno type="Wikidata">Q661056</idno>
          <orgName>Université de Poitiers =  University of Poitiers</orgName>
          <orgName type="acronym">UP</orgName>
          <desc>
            <address>
              <addrLine>15, rue de l'Hôtel Dieu - 86034 Poitiers Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-poitiers.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-520300" status="VALID">
          <orgName>Pôle Biospharm (biologie pharmacie santé publique) [CHU de Poitiers] = Biology, Pharmacy, Public Health Department [Poitiers University Hospital]</orgName>
          <orgName type="acronym">Pôle Biospharm [CHU Poitiers]</orgName>
          <desc>
            <address>
              <addrLine>CHU de Poitiers – 2 rue de la Milétrie – CS 90577 – 86000 Poitiers</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-poitiers.fr/specialites/biologie-medicale/equipe-medicale-et-paramedicale/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300170" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300170" status="VALID">
          <idno type="ROR">https://ror.org/029s6hd13</idno>
          <orgName>Centre hospitalier universitaire de Poitiers = Poitiers University Hospital</orgName>
          <orgName type="acronym">CHU de Poitiers [La Milétrie]</orgName>
          <desc>
            <address>
              <addrLine>2 rue de la Milétrie – 86000 Poitiers – France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-poitiers.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-92114" status="OLD">
          <idno type="ROR">https://ror.org/01x3gbx83</idno>
          <orgName>Institut National de la Recherche Agronomique</orgName>
          <orgName type="acronym">INRA</orgName>
          <date type="start">1946-05-18</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inra.fr</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>